LOCUS       DAVEHY010000001       106415 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVEHY010000001 DAVEHY010000000
VERSION     DAVEHY010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 106415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.001"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            74..397
                     /gene="tnpB"
                     /locus_tag="VUZ44_000001"
     CDS             74..397
                     /gene="tnpB"
                     /locus_tag="VUZ44_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU0318993.1"
                     /translation="MTIHLSSLGQVYLVCGKTGMRQGIDSLAYLVKTHFELNSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(552..859)
                     /locus_tag="VUZ44_000002"
                     /pseudo
     CDS             complement(552..859)
                     /locus_tag="VUZ44_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            979..1290
                     /locus_tag="VUZ44_000003"
     CDS             979..1290
                     /locus_tag="VUZ44_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0318994.1"
                     /translation="MGLPITRKEISNWHIKASQYYLESLYNLLREKLLEQALLHADET
                     SYRVLESDSQLTYYWTFLSGKAEKQGITLYHHDQRRSGSVVQEFLGNYSGYMHCDMLR
                     Q"
     gene            1366..1907
                     /locus_tag="VUZ44_000004"
                     /pseudo
     CDS             1366..1907
                     /locus_tag="VUZ44_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2590..3954)
                     /locus_tag="VUZ44_000005"
     CDS             complement(2590..3954)
                     /locus_tag="VUZ44_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0318995.1"
                     /translation="MVEIKNLSLDYGEERILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRVAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(3942..4637)
                     /locus_tag="VUZ44_000006"
     CDS             complement(3942..4637)
                     /locus_tag="VUZ44_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU0318996.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFIA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            complement(4637..5221)
                     /locus_tag="VUZ44_000007"
     CDS             complement(4637..5221)
                     /locus_tag="VUZ44_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU0318997.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            complement(5232..6953)
                     /locus_tag="VUZ44_000008"
     CDS             complement(5232..6953)
                     /locus_tag="VUZ44_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0318998.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            complement(6937..8691)
                     /locus_tag="VUZ44_000009"
     CDS             complement(6937..8691)
                     /locus_tag="VUZ44_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0318999.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVAFANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            8851..9843
                     /locus_tag="VUZ44_000010"
     CDS             8851..9843
                     /locus_tag="VUZ44_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319000.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            complement(10358..11548)
                     /locus_tag="VUZ44_000011"
     CDS             complement(10358..11548)
                     /locus_tag="VUZ44_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU0319001.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(11545..11910)
                     /locus_tag="VUZ44_000012"
     CDS             complement(11545..11910)
                     /locus_tag="VUZ44_000012"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU0319002.1"
                     /translation="MPNSESTKPKTFEIDCLVGKKHAYEIKWWDATTDGDHITKKHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            complement(11920..12102)
                     /locus_tag="VUZ44_000013"
     CDS             complement(11920..12102)
                     /locus_tag="VUZ44_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU0319003.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            12726..14012
                     /locus_tag="VUZ44_000014"
     CDS             12726..14012
                     /locus_tag="VUZ44_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU0319004.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            14027..14338
                     /locus_tag="VUZ44_000015"
     CDS             14027..14338
                     /locus_tag="VUZ44_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319005.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            14584..15312
                     /locus_tag="VUZ44_000016"
                     /pseudo
     CDS             14584..15312
                     /locus_tag="VUZ44_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            15747..16538
                     /locus_tag="VUZ44_000017"
     CDS             15747..16538
                     /locus_tag="VUZ44_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319006.1"
                     /translation="MNFALNKGEIVGQVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKEMLKDIYLNRSK"
     gene            16554..17282
                     /locus_tag="VUZ44_000018"
     CDS             16554..17282
                     /locus_tag="VUZ44_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0319007.1"
                     /translation="MKLNKFNFIKENIRDLYSSGVIYLGLIISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRIISRDFSHNTISLFYNQQKNRMIYLLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            17668..17877
                     /locus_tag="VUZ44_000019"
     CDS             17668..17877
                     /locus_tag="VUZ44_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319008.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            17867..18355
                     /locus_tag="VUZ44_000020"
     CDS             17867..18355
                     /locus_tag="VUZ44_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319009.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            18471..19931
                     /locus_tag="VUZ44_000021"
     CDS             18471..19931
                     /locus_tag="VUZ44_000021"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU0319010.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDGDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGNQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            19928..20752
                     /gene="nadE"
                     /locus_tag="VUZ44_000022"
     CDS             19928..20752
                     /gene="nadE"
                     /locus_tag="VUZ44_000022"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU0319011.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            21102..21653
                     /locus_tag="VUZ44_000023"
     CDS             21102..21653
                     /locus_tag="VUZ44_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0319012.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKVYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            22368..23060
                     /locus_tag="VUZ44_000024"
                     /pseudo
     CDS             22368..23060
                     /locus_tag="VUZ44_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            23114..23503
                     /locus_tag="VUZ44_000025"
     CDS             23114..23503
                     /locus_tag="VUZ44_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU0319013.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(24164..25192)
                     /gene="queA"
                     /locus_tag="VUZ44_000026"
     CDS             complement(24164..25192)
                     /gene="queA"
                     /locus_tag="VUZ44_000026"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU0319014.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            25344..26051
                     /locus_tag="VUZ44_000027"
     CDS             25344..26051
                     /locus_tag="VUZ44_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU0319015.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            26191..26367
                     /locus_tag="VUZ44_000028"
     CDS             26191..26367
                     /locus_tag="VUZ44_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU0319016.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            26497..27432
                     /locus_tag="VUZ44_000029"
     CDS             26497..27432
                     /locus_tag="VUZ44_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU0319017.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            27425..28213
                     /locus_tag="VUZ44_000030"
     CDS             27425..28213
                     /locus_tag="VUZ44_000030"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU0319018.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            28214..28597
                     /locus_tag="VUZ44_000031"
     CDS             28214..28597
                     /locus_tag="VUZ44_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU0319019.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            28613..29002
                     /locus_tag="VUZ44_000032"
     CDS             28613..29002
                     /locus_tag="VUZ44_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU0319020.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            29086..30216
                     /locus_tag="VUZ44_000033"
     CDS             29086..30216
                     /locus_tag="VUZ44_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU0319021.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            30221..30958
                     /locus_tag="VUZ44_000034"
     CDS             30221..30958
                     /locus_tag="VUZ44_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU0319022.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRCFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEELISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            30969..31742
                     /locus_tag="VUZ44_000035"
     CDS             30969..31742
                     /locus_tag="VUZ44_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU0319023.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEVIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            31732..32349
                     /locus_tag="VUZ44_000036"
     CDS             31732..32349
                     /locus_tag="VUZ44_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU0319024.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            32559..32960
                     /locus_tag="VUZ44_000037"
     CDS             32559..32960
                     /locus_tag="VUZ44_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU0319025.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            32960..33238
                     /locus_tag="VUZ44_000038"
     CDS             32960..33238
                     /locus_tag="VUZ44_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU0319026.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            33228..34001
                     /locus_tag="VUZ44_000039"
     CDS             33228..34001
                     /locus_tag="VUZ44_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU0319027.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            34002..35306
                     /locus_tag="VUZ44_000040"
     CDS             34002..35306
                     /locus_tag="VUZ44_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU0319028.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADCLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            35880..36758
                     /gene="pstS"
                     /locus_tag="VUZ44_000041"
     CDS             35880..36758
                     /gene="pstS"
                     /locus_tag="VUZ44_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU0319029.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            36758..37675
                     /gene="pstC"
                     /locus_tag="VUZ44_000042"
     CDS             36758..37675
                     /gene="pstC"
                     /locus_tag="VUZ44_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU0319030.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            37665..38549
                     /gene="pstA"
                     /locus_tag="VUZ44_000043"
     CDS             37665..38549
                     /gene="pstA"
                     /locus_tag="VUZ44_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU0319031.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVIHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            38560..39363
                     /gene="pstB"
                     /locus_tag="VUZ44_000044"
     CDS             38560..39363
                     /gene="pstB"
                     /locus_tag="VUZ44_000044"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU0319032.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            39376..40134
                     /gene="pstB"
                     /locus_tag="VUZ44_000045"
     CDS             39376..40134
                     /gene="pstB"
                     /locus_tag="VUZ44_000045"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU0319033.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            40146..40799
                     /gene="phoU"
                     /locus_tag="VUZ44_000046"
     CDS             40146..40799
                     /gene="phoU"
                     /locus_tag="VUZ44_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU0319034.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            40956..41771
                     /locus_tag="VUZ44_000047"
     CDS             40956..41771
                     /locus_tag="VUZ44_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU0319035.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(41791..43062)
                     /locus_tag="VUZ44_000048"
     CDS             complement(41791..43062)
                     /locus_tag="VUZ44_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU0319036.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            43204..43935
                     /gene="budA"
                     /locus_tag="VUZ44_000049"
     CDS             43204..43935
                     /gene="budA"
                     /locus_tag="VUZ44_000049"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU0319037.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            43945..44697
                     /locus_tag="VUZ44_000050"
     CDS             43945..44697
                     /locus_tag="VUZ44_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU0319038.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            44809..45714
                     /gene="murB"
                     /locus_tag="VUZ44_000051"
     CDS             44809..45714
                     /gene="murB"
                     /locus_tag="VUZ44_000051"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU0319039.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            45874..47031
                     /locus_tag="VUZ44_000052"
     CDS             45874..47031
                     /locus_tag="VUZ44_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319040.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            47012..47818
                     /locus_tag="VUZ44_000053"
     CDS             47012..47818
                     /locus_tag="VUZ44_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0319041.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            47815..48588
                     /locus_tag="VUZ44_000054"
     CDS             47815..48588
                     /locus_tag="VUZ44_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0319042.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSGHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            48585..49655
                     /locus_tag="VUZ44_000055"
     CDS             48585..49655
                     /locus_tag="VUZ44_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU0319043.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEVPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            49916..50155
                     /locus_tag="VUZ44_000056"
     CDS             49916..50155
                     /locus_tag="VUZ44_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319044.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            50430..50915
                     /locus_tag="VUZ44_000057"
     CDS             50430..50915
                     /locus_tag="VUZ44_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU0319045.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            50937..53555
                     /gene="alaS"
                     /locus_tag="VUZ44_000058"
     CDS             50937..53555
                     /gene="alaS"
                     /locus_tag="VUZ44_000058"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU0319046.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYQELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGRRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(53645..55099)
                     /locus_tag="VUZ44_000059"
     CDS             complement(53645..55099)
                     /locus_tag="VUZ44_000059"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU0319047.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            55278..56027
                     /locus_tag="VUZ44_000060"
     CDS             55278..56027
                     /locus_tag="VUZ44_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319048.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGDIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            56008..57642
                     /locus_tag="VUZ44_000061"
     CDS             56008..57642
                     /locus_tag="VUZ44_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319049.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSSMIAILLVIAFSTSLTAFYNVFYESK
                     DLVSYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            58329..59492
                     /locus_tag="VUZ44_000062"
     CDS             58329..59492
                     /locus_tag="VUZ44_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU0319050.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFNVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASHTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            59489..60166
                     /locus_tag="VUZ44_000063"
     CDS             59489..60166
                     /locus_tag="VUZ44_000063"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU0319051.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            60156..61010
                     /locus_tag="VUZ44_000064"
     CDS             60156..61010
                     /locus_tag="VUZ44_000064"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU0319052.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            61029..62096
                     /locus_tag="VUZ44_000065"
     CDS             61029..62096
                     /locus_tag="VUZ44_000065"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU0319053.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            62106..63272
                     /gene="aroC"
                     /locus_tag="VUZ44_000066"
     CDS             62106..63272
                     /gene="aroC"
                     /locus_tag="VUZ44_000066"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU0319054.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            63282..64385
                     /locus_tag="VUZ44_000067"
     CDS             63282..64385
                     /locus_tag="VUZ44_000067"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU0319055.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            64396..64734
                     /locus_tag="VUZ44_000068"
     CDS             64396..64734
                     /locus_tag="VUZ44_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU0319056.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            64826..66109
                     /gene="aroA"
                     /locus_tag="VUZ44_000069"
     CDS             64826..66109
                     /gene="aroA"
                     /locus_tag="VUZ44_000069"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU0319057.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            66102..66578
                     /locus_tag="VUZ44_000070"
     CDS             66102..66578
                     /locus_tag="VUZ44_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU0319058.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEETFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            66575..67423
                     /gene="pheA"
                     /locus_tag="VUZ44_000071"
     CDS             66575..67423
                     /gene="pheA"
                     /locus_tag="VUZ44_000071"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU0319059.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYTEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            67420..68694
                     /gene="psr"
                     /locus_tag="VUZ44_000072"
     CDS             67420..68694
                     /gene="psr"
                     /locus_tag="VUZ44_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU0319060.1"
                     /translation="MSKENLLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            68973..69818
                     /locus_tag="VUZ44_000073"
     CDS             68973..69818
                     /locus_tag="VUZ44_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU0319061.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            69808..70911
                     /locus_tag="VUZ44_000074"
     CDS             69808..70911
                     /locus_tag="VUZ44_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU0319062.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            70913..71899
                     /locus_tag="VUZ44_000075"
     CDS             70913..71899
                     /locus_tag="VUZ44_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0319063.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            71915..73348
                     /locus_tag="VUZ44_000076"
     CDS             71915..73348
                     /locus_tag="VUZ44_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU0319064.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMI
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            73377..74411
                     /locus_tag="VUZ44_000077"
     CDS             73377..74411
                     /locus_tag="VUZ44_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU0319065.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            74611..75348
                     /gene="mecA"
                     /locus_tag="VUZ44_000078"
     CDS             74611..75348
                     /gene="mecA"
                     /locus_tag="VUZ44_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU0319066.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            75499..76785
                     /locus_tag="VUZ44_000079"
     CDS             75499..76785
                     /locus_tag="VUZ44_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU0319067.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            76787..77656
                     /locus_tag="VUZ44_000080"
     CDS             76787..77656
                     /locus_tag="VUZ44_000080"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU0319068.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            77732..77803
                     /locus_tag="VUZ44_000081"
                     /pseudo
     CDS             77732..77803
                     /locus_tag="VUZ44_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            77951..78889
                     /gene="msrB"
                     /locus_tag="VUZ44_000082"
     CDS             77951..78889
                     /gene="msrB"
                     /locus_tag="VUZ44_000082"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU0319069.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            78949..80673
                     /locus_tag="VUZ44_000083"
     CDS             78949..80673
                     /locus_tag="VUZ44_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319070.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLIQLILGLYPVNKGRIDL
                     YLDGLSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            80675..82423
                     /locus_tag="VUZ44_000084"
     CDS             80675..82423
                     /locus_tag="VUZ44_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319071.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSLVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFVKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            82680..83939
                     /locus_tag="VUZ44_000085"
     CDS             82680..83939
                     /locus_tag="VUZ44_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU0319072.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIMDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    84015..84150
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            84189..84689
                     /locus_tag="VUZ44_000086"
     CDS             84189..84689
                     /locus_tag="VUZ44_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU0319073.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            84765..85133
                     /gene="rplL"
                     /locus_tag="VUZ44_000087"
     CDS             84765..85133
                     /gene="rplL"
                     /locus_tag="VUZ44_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU0319074.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            85333..85506
                     /locus_tag="VUZ44_000088"
     CDS             85333..85506
                     /locus_tag="VUZ44_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319075.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQS"
     gene            85503..85751
                     /locus_tag="VUZ44_000089"
                     /pseudo
     CDS             85503..85751
                     /locus_tag="VUZ44_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            85765..86088
                     /locus_tag="VUZ44_000090"
     CDS             85765..86088
                     /locus_tag="VUZ44_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319076.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSHD"
     gene            86081..86461
                     /locus_tag="VUZ44_000091"
     CDS             86081..86461
                     /locus_tag="VUZ44_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU0319077.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            86474..86707
                     /locus_tag="VUZ44_000092"
     CDS             86474..86707
                     /locus_tag="VUZ44_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU0319078.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQILDLDYEDLFRR"
     gene            86710..87297
                     /locus_tag="VUZ44_000093"
     CDS             86710..87297
                     /locus_tag="VUZ44_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0319079.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
     gene            87697..88506
                     /locus_tag="VUZ44_000094"
     CDS             87697..88506
                     /locus_tag="VUZ44_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU0319080.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            88511..89212
                     /locus_tag="VUZ44_000095"
     CDS             88511..89212
                     /locus_tag="VUZ44_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU0319081.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            89237..90154
                     /locus_tag="VUZ44_000096"
     CDS             89237..90154
                     /locus_tag="VUZ44_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU0319082.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            90182..91723
                     /locus_tag="VUZ44_000097"
     CDS             90182..91723
                     /locus_tag="VUZ44_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEU0319083.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            91742..92200
                     /locus_tag="VUZ44_000098"
     CDS             91742..92200
                     /locus_tag="VUZ44_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU0319084.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            92202..94424
                     /locus_tag="VUZ44_000099"
     CDS             92202..94424
                     /locus_tag="VUZ44_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEU0319085.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            94464..95573
                     /locus_tag="VUZ44_000100"
     CDS             94464..95573
                     /locus_tag="VUZ44_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU0319086.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            95730..96620
                     /locus_tag="VUZ44_000101"
     CDS             95730..96620
                     /locus_tag="VUZ44_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU0319087.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            96645..96968
                     /locus_tag="VUZ44_000102"
     CDS             96645..96968
                     /locus_tag="VUZ44_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319088.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            96958..98949
                     /locus_tag="VUZ44_000103"
     CDS             96958..98949
                     /locus_tag="VUZ44_000103"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEU0319089.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            98965..99441
                     /locus_tag="VUZ44_000104"
     CDS             98965..99441
                     /locus_tag="VUZ44_000104"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEU0319090.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            99475..100056
                     /locus_tag="VUZ44_000105"
     CDS             99475..100056
                     /locus_tag="VUZ44_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319091.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            100121..101128
                     /locus_tag="VUZ44_000106"
     CDS             100121..101128
                     /locus_tag="VUZ44_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEU0319092.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILES
                     TPYHLSIDILEDPSQTEISLMTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYG
                     S"
     gene            101118..101438
                     /locus_tag="VUZ44_000107"
     CDS             101118..101438
                     /locus_tag="VUZ44_000107"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEU0319093.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            101501..103276
                     /locus_tag="VUZ44_000108"
     CDS             101501..103276
                     /locus_tag="VUZ44_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEU0319094.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            103277..104662
                     /locus_tag="VUZ44_000109"
     CDS             103277..104662
                     /locus_tag="VUZ44_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEU0319095.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            104685..105296
                     /locus_tag="VUZ44_000110"
     CDS             104685..105296
                     /locus_tag="VUZ44_000110"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEU0319096.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            105374..105493
                     /locus_tag="VUZ44_000111"
                     /pseudo
     CDS             105374..105493
                     /locus_tag="VUZ44_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218559.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATPase"
     gene            105569..105754
                     /locus_tag="VUZ44_000112"
     CDS             105569..105754
                     /locus_tag="VUZ44_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319097.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            105735..106058
                     /gene="tnpB"
                     /locus_tag="VUZ44_000113"
     CDS             105735..106058
                     /gene="tnpB"
                     /locus_tag="VUZ44_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU0319098.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(106213..106415)
                     /locus_tag="VUZ44_000114"
                     /pseudo
     CDS             complement(106213..106415)
                     /locus_tag="VUZ44_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        32398 a        18666 c        22350 g        33001 t
ORIGIN      
        1 aagcttgaag taagtttttt tcaatctctc aatctcgaaa tgatagaaca gcttttggat
       61 aaggtgttgc tctatgacaa ttcatctatc tagcctaggg caggtctatc tcgtatgtgg
      121 gaaaacgggt atgagacaag gaatcgattc actggcttat ctggttaaaa cccactttga
      181 attgaattct ttctcaggtc aagtttttct cttttgtggt ggacgtaaag accgctttaa
      241 agtcctttac tgggatggtc aaggattttg gctattatat aaacgctttg agaacggcag
      301 actgacttgg cccagtacag aaaaggatgt caaagctctc gcacctgaac aagtagattg
      361 gctgatgaaa ggcttttcta tcactccaaa aatatagtag attgaaacta gaatagtaca
      421 cctttgcttc taaaacattg ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt
      481 attatttcat tttactataa atccatcaga aagtcgtgat ttctattgaa atgaggactt
      541 tctttttata ctcatctgct ttcaaaaagc attctagtcc atctccgatt aacgatggac
      601 tttatcacct ccttctccag tccttgtata acatcttgaa gttgattcat gacatcttcc
      661 aaagtttgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca cacttgttca
      721 atgggttcat ctctggtgtg tatggaggaa taaatgcaaa gccaatatta gtcggaatct
      781 ttaaggtact tgatttatgc catatagcat tgttcataac gagtaaaaga taatcatctg
      841 gataagcttg tgaaagctcc tattcctaaa gcccctttgg cgcatagcct tggctcagct
      901 tctattatcg ctcacaccat ccatcagaag tttaatctga aggtacctaa ttatcgctaa
      961 gaagaagatt gggctaagat gggtttacca atcacacgta aggaaatttc taattggcat
     1021 atcaaggcga gtcaatacta tttagagtcc ctttataacc ttttacgaga aaagttgtta
     1081 gaacaagctc ttcttcatgc agatgaaacc tcttatcggg tcttagaaag tgatagtcag
     1141 ctgacttact attggacttt tttgtctggg aaagctgaga aacaagggat tacgctgtac
     1201 caccatgatc agcgtcggag tggttcggta gtgcaagaat tcctaggaaa ttattctggc
     1261 tatatgcatt gtgatatgtt gcggcagtaa cttagaactt tagtcctcta gttctgccta
     1321 tgcgatagca gtctaaggtt taggagcaag gcgacgctaa gcttggtaaa ctgcgaaccg
     1381 ctagaagctt atcgtcaact ggaagaagct gaacttgttg gatgttgggc gcatgtgaga
     1441 aggaaatttt ttgaagcgac ccccaagcaa gcagataaat catccttagg agctaaaggt
     1501 ttagcctatc gtgaccagtt atttgccttg gaaagagact gggaggcttt gccagctgat
     1561 gaacgactac agaaacgtcc agcccctaat ggaagacttc tttgcttggt gccgccgtca
     1621 gtcagtttta gcaggttcaa aactaggaag ggcaattgaa tacagcctca agtataaaga
     1681 aacctttaag accattttaa aagacggaca tctggtcctt tccaataatc tagctgaacg
     1741 cgccattaaa tcattggtta tgggacggag taaaagagtc cagtggactc ttttagcctg
     1801 agctcagttt aaaaaagcga gggtggttat tttctcaaag ttttgaagga gctaaagcaa
     1861 gagctattat tatgagtttg ttggaaacag ctaaacgtca tcaattatag tgcgttgaat
     1921 ctataacagt acgcatcgac tgctaaaata tttctataaa tcaattttcc tttcctaatc
     1981 gatttgttca tatcttattt caatccatta taaatagtga gaaatatcta tcctatcttc
     2041 tagaatgtct tccaaacgag gaaactctcg taaacaaaga ggttttagag gcctatttac
     2101 cgtggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta ggaactatat
     2161 atgagttctc tagtctggag atttttcaat atacttcgtt attgggcggt tacaatttat
     2221 tatatgaaaa tcccatatca ttctccaatt ctatatttta cctttctaaa tgtatagatt
     2281 aactacctaa ttatatcata taacgcagat tcctttcaat cgtatgattt actgcattaa
     2341 attaagtaaa aaaataaagg cagtccgaag actgccgata tttatctctc atctctttaa
     2401 ttatggtaag taaataaata atttccctaa agatatggaa attattaata ctataaatac
     2461 atattataaa gtttataaat actgtaaaaa tcctgaagtt aattttctaa taaatatcaa
     2521 tatgtgttag tatcttttaa atttttagac aatttaccag ttctatagac atgtttaaca
     2581 gactctattt tacaattcaa aaatttcatc tgccacttca tttaaaaatt ctatatcatg
     2641 ggaaacaata aaaattattt tatccatggt tttatactta ttaatcagtt cagatatttt
     2701 tatcatattg gaataatcca taccacttga aggttcgtca aaaaagacaa atggagaatt
     2761 cttgcacata acagatgcta ttgcaaccct ttgcttttgc cctcctgata aactcatcgg
     2821 atgcctttca ataaattcgt ccaggcctaa atcttttaaa atgattttcg ccttttcttc
     2881 atcaaaattc tttactccta atctaagctc gttgaatact tcatctgtga ataattgatg
     2941 atttacatct tgcataacaa gtgaagagtt tttgagtctt tcttttttag atagcttctc
     3001 tcccttaaaa taaatttctt cttttgattt tttctcaaga cctattaaac atcttaaaag
     3061 cgttgatttt cctcgtccgt tggatcctat tatgccataa attttcccaa gcttgaacga
     3121 aatatctttt aagcttaaac actcatcatc agtaaatttg tagctaagat tttttatctg
     3181 atactctcca ccttctttta aataaggaac ttttaattta cttaattctt tatctcttaa
     3241 acttaaagca tttaattcat ttttatctag ctttaaaaat tcacttctag tataagtttt
     3301 tttaagcttt cctttatcta ttaaaaatac acggtcaact atgtccatca aataataaat
     3361 tctatgctct gcaacaatta tgcttatgcc tttctctttt aatatcttta gcatctttgc
     3421 caaaacactt atgcttttaa tatctaaatt cgatgaaggc tcatccataa ctataatctt
     3481 tgtacctgct atataagaag ctgcaatgca aagaatttgt ttttcaccgc cggatagatt
     3541 aaatatattt ctgttcaaaa gattttttat cgggaatatc tcaagcatat ccttcaaacg
     3601 cctgtccatc tcttctcttg caagaccgat attttccaaa taaaataata attctaatgt
     3661 cgtattgaca ttaaaaaaat aggtcttagg attttgaaaa acagttgaaa caagcattga
     3721 gatttgataa agttccaaat tttttatatt cttaccatca ataattattt cgccctttgt
     3781 ctttgcgtta tcatacctta cagctagtcc attgattgaa tttattaaag atgacttacc
     3841 atttccactt tttcctgtaa atagcacgca ctctccctcg gctatggata gtgatatatc
     3901 atctaatata cgctcttcac cataatcaag acttaaattt tttatttcaa ccatattaag
     3961 cctcccacaa taagtccagc aaccgctaaa acataaacaa aatcaattag ctgtatcttt
     4021 acgcgaatgt atctggtctt ggcaattgga ttttctattg cctttgtttc tgccgctttt
     4081 gcaatgtcat ctgatatatt agatgatata atgagtagtg gcatagaaac atattcaaga
     4141 tatttgactg ggtttttaaa acttatccct cttactctca tagccatttt gatgtttttc
     4201 ttctcctcct taaaagatgg gaagaatcta aacataaccg caataggtat ggatacattc
     4261 tttgaaatct taagcttatc catcgatgaa attattgcgc ctacatccga ggtctttatc
     4321 ataaagcttg ctgctataaa tggtaaaata aacattctaa taacaatagg tatactcaaa
     4381 aacatcttaa ctatagggtt taattcagat aacaccataa aattaggcaa ggagtaaagt
     4441 atcccacaca atataatcca tttgaaaagt gtttttttgt atccattcaa ataaagcaaa
     4501 ataccaataa gacaaacaat tgccagctca aaacggatgt ttatgctatg cataacagtt
     4561 aagcctgtga taaatacgac taatatctta gagatcggat tgggattaaa gggagcattt
     4621 gaagaaaaag taggcattat acaatgcctg ctttttcaaa gtgttttttc aatagagcct
     4681 tgcctatata tgctccaaga attcctccta agaaagcacc taaggctact aaagccatat
     4741 gaggataagt tattaacttt tctaacacat caacataatc ttttcccatc gtcatcaaag
     4801 accactccat atatttttct tttgctaaaa gcatttgcat taaagagcta catatccatg
     4861 tgctgaagat tgcataagaa agcatattgt atttaaatga attataatta ccaatctttc
     4921 taattaattc tgctattatc attactataa gtgataaaac cacaactacg taggtatgac
     4981 cagctgcaaa catcacaagt ggtgatatca taccaaatat aaatagtgcc catggctttt
     5041 gaaccttagc cataaataac ataacaacag ttcctgcaac tatggctaat actgtcgggt
     5101 atattaagaa caatattgga atcaagccca tcataccaac tccaaacatg aaggcaaaat
     5161 aaattacgcc aaaaacaccg atgcttacta aatcttttac ttttaatttt ttattatcca
     5221 ttgtagtcct cctaataaat aaattcttct gccatttttg tcttttctat taaatttttg
     5281 taaatttttg atttttgtaa aagctcttca tgcttacctt cgctttctac tcttccgttt
     5341 tgaagaacta ctatcttgtc tgcattttct atggatttca ttctatgtga aatgattaca
     5401 acagttttat ctttaactaa attatttaaa gactcttgaa tctttttctc gttgttaaca
     5461 tcaaggcttg ctgttatctc atctaagatc aatatcggcg catcttttaa gaaggctctg
     5521 gctattgata atctttgtct ttctcctcct gatagctcag ctccgttctc accaataact
     5581 gtatcgaaac ctttatccat tttttctata aaatctgtgc aatttgcaag ttttgctgct
     5641 cttttaacct cttcgtcact tgcatcttgc tttccgattc taatattttc cataacgctt
     5701 tgattaaaga gaaccacatc ttggaaaact atagagacct tatcaaaaag agattctgtt
     5761 gatatttctt ttatatcttt gccatcgatt aagatttgtc ccttgtcata atcataaagt
     5821 cttgatataa gtttcaagat agttgtttta ccgcagccac ttgcacctac caaagcagtg
     5881 acctctccct gcttagcttt aaaacttaca ccatttaaaa cttttgcgtc tttattgtag
     5941 gcaaactcaa catcttttag atcaatatca aattttttta agctatagtc atcgccttct
     6001 tgtaaatctt gattttgaat ttcttttaat ctttctattt tgggcgataa ataaaatatt
     6061 tccatcaagc cctctttaga tgcatctaaa gagtctttta tcttcatagc agctagtaaa
     6121 tatcctataa ggtagagaga atttatctct ttattaataa ttagatttac gccgacaaat
     6181 atcacaacag caagagatat aaagctaaat attgaagata tagacaaagt taaaattgta
     6241 gttacttccg cctttaagtg tactctctca ctatcttcca tttttttata taagtcatct
     6301 ttaatatcct tcgataaatt atatgcttta atctccattt gcatttcgat attttcttga
     6361 aagctttctg agttttttct taagacatca taatatctat tctgtccatt aacctgatat
     6421 tttttagata aaggtataaa tataaagctt aaaatagatg gaataattac agctaaaccc
     6481 atcttgacat tgcccgctag catcattaca gatattaatg ggaaaaacag taccatgccg
     6541 cccacctttg gtattgagtg gctcattgca tgctctatgc cttcaatatc agccatgatt
     6601 gtttgtgaaa tgtcggaaat gtcatgttta gaaaagtaag atagaggtaa ttttgataaa
     6661 ttctccgctg tccttattct taaatctgca ctttcttgat aggttgtgtt atataattta
     6721 tcgtattcga tagaaagcaa aatatacatt gctatcaaag tcaaaactga gaatactata
     6781 taaaagccat tgcttttgcc catattttcc aaaacttcct gagcaaaaat cataagtaat
     6841 atggcaggaa gcatgtttat acaataaacg aaaaatgaag ccagtgttgc tttacttaaa
     6901 tttcttgctc ctccatctgt aagagcaaat ctttttttat aaaactcttt catttgaaac
     6961 cctccattca ttcgcactgt taaacatctc ttgcaggctc ttataccttg tatcttttga
     7021 cattaattct ttgtcagacc ctctttctat aatttttcca ctatccatga caataatttc
     7081 atcaaggtct ttaattgtag atagcctgtg tgcaatcatg ataactgttt tatccttcat
     7141 aagattttta aaagcttttt gcaattcaaa ctcgttatct gggtcaatag atgctgatgc
     7201 ttcatccata ataataattt tggaatcctt taaaattgct ctagcaattg caattctttg
     7261 tttttctcca ccggataaat aaacaccttt tgagcctatg attgtatttt ctctttctgg
     7321 gaatttgtct aatattaaat cgcatcctgc taattttaag gctctcataa cgtcatcttt
     7381 cgtcgcatct ttattagcga aagctacatt atcataaatg ctcttcttga ataattttga
     7441 atcttgaaaa acaaaggaaa tggctttaat taaggcttcg tcagaatatt cacttattgc
     7501 tatcccgcct atctttatgc ttcctttatt aacattataa aaacctgata taagttttgc
     7561 tactgttgat ttgcctgatc cagatgaacc gacaagtgcg taggactttc cttcttctaa
     7621 attaaaggat aaattttcaa tgacagcttt atcattataa gcaaagctaa cattctcaaa
     7681 ttctatatta tagtttttaa aattattgac attaccatgc actaatttgt ctttttgcat
     7741 atcttcgtaa agcgcctcta aagtatctac tgcataattt ccttgagaaa tatacatgga
     7801 gtaccacatc attctcatga atgaaacaaa gagaactcct gataaaaata aaatcatgat
     7861 aagctcaagt aaaatcacct ttgcgctagc taagctagtc ataaaataaa ctataggaat
     7921 aattaaaatt gcaatcagtc caaaaaataa ccattgatac aaaacataag gccttttaca
     7981 agatagggaa taatcataag catactttga gtaatctttt atagccttgt aaaagctttt
     8041 aaatgactct acatttgctt taaatatttt tacaacttgc attcctctca cgtactcaac
     8101 agtttcagca cttagtttag atagggattc ttggtatatc ttcataaatt cttgctcgcc
     8161 catcatcgcc cctaaaatta agccaccaat tatagtaaga gcaagcaaaa ttatgccaac
     8221 tcttatactt actataaagc caagtgcaag tacaagtacg ggtgtgatta ttgcctgaga
     8281 actatcggga atcatgtgtg ctaccacctg atgagtttgt gctgcattat catctatgat
     8341 ctttcttatt tgaccagatg gatttaagtc aaagaaccta aaacttgctt tttccagacc
     8401 atcgattccc ctttttctta aatttgtttc aagcctgaat cccaagatat gtgaaaacat
     8461 tcctgagaca aaataaaata tcgctccact tgttagtgta ataacagatt ttaatgctat
     8521 actctctgca ccggataaat ttgaattaat tattaactta tctagaaatt tgtagattaa
     8581 ataatatcca tatactgtaa gtagagcaga tatagcagaa aaaattatgg ccaaaacccc
     8641 aagatatttc ttatcttgga cataagcaaa tagttttttg taaatcttca taagcatatc
     8701 tcctttcttt aatatccctt ttagatataa attcgcttaa ttgataatat ctatcattgc
     8761 ttttctatta tacatctgtt ataattacta atacaatagt tttgaattaa taaggctaat
     8821 tggaatattg tctaaaaggg atagtgtgtt atgtcatatt atgattttgt aaaagattat
     8881 atgaaagtag atgaatgtaa aaacaatgag aagtattcaa gtgcaggtca tacattttgt
     8941 tggaaaaaag agaattcaac ttatgcagaa ggcctatatt ggttttatga aggaggcagc
     9001 ttcattatcg atatacatga tttttatatc aaagaggaag tagttcaaaa tagcacttat
     9061 agtatgtcag actatgtttc aatttattca agttacattg tcagtgcaaa cggagaaaag
     9121 tttaatccgt atcaaactat taccgcaaac tctctatgta cttttgattt tgataatata
     9181 aaagatgatt ttgttttttt attacacgag aattgttgtt atcttgctgt ttccattggt
     9241 tttaaaaaag agctaataga aaaacattta gcatctatta acattaatcc agaatctttt
     9301 tattcaacct tgcttcaacc gaatcaaata atacttacaa aggccttaga aagagtggca
     9361 atggaaatat taaattgtaa gatggacgct cctgccgctg attttttctt taaagcaaag
     9421 gcaaatgaat ggataagtat agtaattgac acatacttaa atagaaaaaa atataaaatt
     9481 gaaattgatg atgataaagc acttgaagat gtagcaagat tcttagatga tcattttgca
     9541 acgaatgtaa atcaaggcac gcttgaaaaa atatctaaaa tgagtggtac taaattaaaa
     9601 aatttattta aggaaaaata ttgtcaaagc attacagagt acactcaaag aaaaagaatg
     9661 aatgtagctg aaactcttct tttaaacact gaactaccta taaaagagat agcagaatct
     9721 gttggatatt catctgccag caaattttct atctattata aaagatacaa gggaaaactt
     9781 ccaagtgaag tccgtaattt agcttgcaaa catcacaatt ttaaatgcga ttattgtgat
     9841 taaagtaatt ttttacaagc catgttttta tatgaattta agtgtatatg tgcatatata
     9901 gtctgaataa atttgatttg aaaaatggat aaaaaaataa aggcagtccg aagaccgcca
     9961 atatttatct ctctgcacct ttgctatggt ctttcttatt tgacttagat ttgtcatctg
    10021 tcttaaagct ttttatttgc cctaatatgg actttttatc cttgtcttga ctctttactt
    10081 gttcttttgc ttttaagagc ttagaagaca aaaagagata ttatattaaa acaatatttc
    10141 tccggtactg ggactgggac gggactaaaa atctgaaaac gtcctataat taggtggatt
    10201 tagtgatatt ataaaaaata gaatctagta ttttgaatgg ttttggatat attgtacgtt
    10261 tggaaaagaa gaatgggagt aattttaaac taacaaaaaa atgctttgaa atcagtgttt
    10321 cagagcattt ttgttctttc tgtaaataat ttgcaaacta tagtaactgt tgacttttac
    10381 ttaaccattt ttcgattgta agttcaaaat ggtcaactac tattatattt tcaggaatcg
    10441 tatcaaaatc aaataataaa ttatctgaat gagtttttat aactactcca aaatcaagtt
    10501 ttttggagtt tatagcattc tgtaataaag agatactctc attcagacat tcattatttt
    10561 tttgaatttt tataggtatc ggtttttttt gaaaatgttt aggtaaaaaa ccatcaattc
    10621 ctttatttct ttgaacaatt tttgcctgta ataatttaag aatgttttcc tcttcctcag
    10681 ttttggttct atatgcttcg attcctttat tcaataaatt tgaacttgtt tttataacat
    10741 tttccagacg ttgctgagtt atattgatag cttcctcaga taaatcaatc cccatataat
    10801 ttctattcaa aatcttggag gctactaaag tagttccact tccacagaac gggtctaaaa
    10861 ctatatcatt tttatcagta gcaatcttta taatttgttc taataacaga ataggttttt
    10921 gtgtaggata acctactctt tctttagctt ttggattaag aaatggtata ttccaaacat
    10981 ctgaaagggg aactccattt ttctcttttg ctagaatata gttaccatta ttatcaacct
    11041 tatatatagt tttagagttt ccatctcgtt ttcgttccac tagtatttgg tcgatatttg
    11101 tagtagaaga atactctgta aaaattgtat taaatttaaa atcttttgac tttgaataaa
    11161 agtaaatgtt ttgatgattg ttcaataatc ccttttttga attagaccac cgtttatagt
    11221 tccatataat ttcgctttga aacatatctg ctccaaagat attatctaaa attaatctaa
    11281 tatgatgatt tgcaatttta tcacaatgaa cgaaaatact gccactattt tttagcactc
    11341 ttttgcattc ttctaatctt acagacaaaa attctttgta atcctcaatc gaagtccacg
    11401 tatcttcgaa tgaatacata atatttttgt tattagataa tttttgggtt ttctgtgtaa
    11461 agaaaggagg gtccatatag attaaatcaa tacttgagga ttcaatagtt tttaatattt
    11521 ctaagttatc tccttttaat actgtcattt tgattttacc cctgtttttt tatttgcaat
    11581 atctgttaga atactaagta aatcaatacc ggtcactgct cttaaatgtt cccaggcaga
    11641 atctccataa taatatttcc ctccaatacc gttatacaat gtttctaaag tttgctgaat
    11701 ttttatagct tgagttctat ttggatagta gaacattaac cgaattggta tatatccttt
    11761 gttatgaata acttttattc tagtgtgttt tttagttata tggtctccat ctgtagttgc
    11821 atcccaccat tttatttcgt atgcgtgttt ttttccgact aaacaatcaa tttcaaaagt
    11881 cttaggtttt gtactttcag aattaggaat gttaactttt taagtatttt ctgtaccaaa
    11941 tttttcgtta aagcatagta ctgcagcttc ttctaaaaat gaaccagcat atttgtataa
    12001 aaaacgacct ttattttgat acaaatcgat attttctcct tcttcaaatg aaatacctaa
    12061 aactctgtat atcaaataat ggctcttatt atcatttgcc atttcacgaa ctctctcttg
    12121 aactttgatg tttaagttat cagaatattt cttagctaat ttttcgattt tttctttcta
    12181 attcggtcat ttctatcctc ttgttataaa taaaattata gctatatcta ttataacatg
    12241 gtttaataaa ttctttgagc ttttttcttt ttaaatattg attgtttcta aaaattctag
    12301 taatattgct atttctcatt tttccaaata tgttattcaa cttattagct acgtctctat
    12361 tcatatttgg gtataaaaca aaaaatcaat tctaacagtt ttatatcaga ataataaata
    12421 aaaaagcgat attctagact gtatcaatcc ttttccatta taggagcaac agagtgggag
    12481 tagtcatcta aggactaatt tatgtatttt tacgagtcag tatctttgga tactggtttt
    12541 tacttttcta gactttttga ctacttgtta aaactgggat aattttcgac tgtttaacag
    12601 ttattatgca aagtctaaaa gattagaatt gtcaaaacaa tccgtctagg cttgatttta
    12661 tcctttattt actataaaat gagaaggaaa aatgtcaaac ttttatattg caaataggag
    12721 aaatcatgac aaaaacatta aaacgtcctg aggttttatc acctgcaggg actttagaga
    12781 agctaaaggt agctgttcag tatggagcag atgctgtctt tatcggtggt caggcctatg
    12841 gtcttcgtag ccgtgcggga aactttactt tcgaacagat ggaagaaggc gtgcagtttg
    12901 cggccaagta tggtgccaag gtctatgtag cggctaatat ggttatgcac gaaggaaatg
    12961 aagctggtgc tggtgagtgg ttccgtaaac tgcgtgatat cgggattgca gcagttatcg
    13021 tatctgaccc agccttgatt atgattgcag cgactgaagc accaggcctt gaaatccacc
    13081 tttctaccca agccagtgcc actaactatg aaacccttga gttctggaaa gagctaggct
    13141 tgactcgtgt cgttttagca cgtgaggttt caatgaaaga attagctgaa atccgcaaac
    13201 gtacagatgt tgaaattgaa gcctttgtcc atggagctat gtgtatttca tactctggac
    13261 gttgtactct ttcaaaccac atgagtatgc gtgatgccaa ccgtggtggg tgttctcagt
    13321 catgccgttg gaaatacgac ctttacgata tgccatttgg gaaagaacgt aagagtttga
    13381 agggtgagat tctagaagaa ttttcaatgt cagccgttga tatgtctatg attgaccaca
    13441 ttccagatat gattgaaaat ggtgtggaca gtctaaaaat cgaaggacgt atgaagtcta
    13501 ttcactacgt atcaacagta accaactgct acaaggcggc tgtggatgcc tatcttgaaa
    13561 gttctgaaaa gtttgaagcc atcaaacaaa acttagtgga cgagatgtgg aaggttgccc
    13621 aacgtgaact ggctacagga ttttactatg gtacaccatc tgaaaatgag cagttgtttg
    13681 gtgctcgtcg taaaattcct gagtacaagt ttgtcgctga agtggtttct tatgatgatg
    13741 cgacacaaac agcaactatt cgtcaacgaa acgtcattaa cgaaggggac caagttgagt
    13801 tttatggtcc aggtttccgt cattttgaaa cctatattga agatttgcat gatgccaaag
    13861 gcaataaaat cgaccgcgct ccaaatccaa tggaactatt gactattaag gtgcctcaac
    13921 ctgttcaagc tggagacatg gttcgtgcat taaaagaagg actcatcaat ctttataagg
    13981 aagatggaac cagcgtcaca gttcgagctt aagaaaggaa aaggaaatga tagaggcaca
    14041 gggtttctta gtggataagc aaacaagatg cattcattac catagcaagc tggatattat
    14101 tgctttacaa tgctatgatt gtaaaaagta ctatgcttgt tatcggtgtc atgattcatt
    14161 agaaaatcac ccttttgagc cgtatccctt atctttgata caggataagc ctattttatg
    14221 tggtgtttgt ctaaaactac taacgtataa gcaatataaa gaaagcttaa gttgcccctt
    14281 ttgtttttct cgctttaatc caggttgcca aaatcataag gaacgctatt ttaaatagca
    14341 aatcatctag ttttgaagta ggagaaaact caattccaag agaaaatgaa gtaaatcttc
    14401 ccacaataaa acgcataata tcaagattgt tcaatacctg atactatgcg tttttaagat
    14461 tttaaagact tttttccttt atctggtatt ttgactactt gttaaaactg ggttaatttt
    14521 caactgttta acagttatta tgcaaagtct aaaaggttag aattgtcaaa acaatccgtc
    14581 tagagtatgc gtgatgccaa ccgtggtgga tgttctcagt catgccgttg gaagtacgac
    14641 ctttacgata tgccatttgg gaaagaacgt aagagtttgc agggtgagat tccagaagaa
    14701 ttttcaatgt cagccgttga tatgtctatg attgaccata tctcagatat gattgaaaat
    14761 ggtgtggaca gtctaaaaat cgaaggacgt atggagtcta ttcactatgt atcaacagta
    14821 accaactgct acaaggcggc tgtggatgcc tatcttgaaa gtcctgaaaa gtttgaagct
    14881 atcaaacaag acttggtgga cgagatgtgg aaggttgccc aacgtgaact ggctacagga
    14941 ttttactatg gtacaccatc tgaaaatgag cagttgtttg gtgctcgtcg taaaattcct
    15001 gagtacaagt ttgtcgctga agtggtttct tatgatgatg cggcacaaac agcaactatt
    15061 cgtcaacgaa atgtcattaa cgaaggggac caagttgagt tttatggtcc aggtttccgt
    15121 cattttgaaa cctatattga agatttgcat gatgccaaag gaaataaaat cgaccgcgct
    15181 ccaaatccaa tggaactatt gactattaaa gtcccacaac ctgttcaagc tggagacatg
    15241 gttcgagctc ttaaagaggg gcttatcaat ctttataagg aagatggaac cagcgtcaca
    15301 gttcgtgctt aatgtagttg tttagtttta aaaaattatg caaagctcca tatacaacac
    15361 ttaaacgaga ttaaagaatg gcgaaatccc ctgatgcgca agagattagc tgtctttttt
    15421 attttttaag tgataaagtc ggagcttagg tatcaaagcc tatcaaatta aacaaagaag
    15481 cgatgtctta gatattttga aaaaaattaa taagcagaaa actctctatt attttgttgt
    15541 atagagtttt ttgttaatca aatttcacaa aatgacattt atatattgca ttaagttaga
    15601 tatatgatat aatattgtta aaaagaggcg caacttttta aaattaatga gaatcaaaga
    15661 gaaaaccaat aatattaatg gaggaataaa aaatgtaagt tataaatgta agtaagcatt
    15721 atggtcattc aatcattctc aaagacataa attttgcact taacaagggt gaaattgttg
    15781 gtcaagtagg gagaaatgga gttggtaaga gtacgttgat gaaaattctt gttcagaata
    15841 atcaaccgac ttcaggtaat attataagca gtgataatgt tgggtattta atcgaagaac
    15901 caaaattatt tttatctaaa acaggtttag agaatttaaa atatttgtca aatttatatg
    15961 gtgttgacta caatcaagaa agatttagaa gtttgatcca agagttagat ttgactcagt
    16021 ctattaataa aaaagtaaag acctattctt tgggtacaaa acaaaaatta gctttgcttc
    16081 taactctcgt tacggaacct gatatattga ttttagatga accgactaat ggtttagata
    16141 ttgaatcatc acaaatagtt ttatcggttc taaaaaattt agctttacat gaaaatgtgg
    16201 gaattttaat atcgagtcat aaattagaag atattgaaga aatttgtgag agggttcttt
    16261 tcttggagaa cgggcttttg acatttcaaa aagtaggaaa agatagtcat aatttcttgt
    16321 ttgagatagc tttttcatca gctacagata gagacatttt cattaccaaa caagaatttg
    16381 gggatattgt tcaggaagag ggactgagaa ttactatgtc tgggaatatt caaagtagtg
    16441 agctttttaa attttttaac gaaaactcta ttaaagtagt tgattttgaa actaaaaaag
    16501 agatgcttaa agatatttat ctaaatcgtt caaaataaag gaaggttata atcatgaaat
    16561 taaataaatt taattttatt aaggaaaata taagggattt atattcatca ggcgtaatat
    16621 atctcggttt gattatctcg tttataccgc cgatattgct tacattcttt attctaaaga
    16681 ctcaagggac atcgcttggt attaagcata tttcaaactt ttatgctatg ctcggtatgt
    16741 taatggctgt tatacatgct aaccgaatta ttagcaggga tttttcccac aatacgatca
    16801 gtttatttta taatcaacag aaaaatcgga tgatttacct cttgtctaat tttctatatg
    16861 ccatctcagt ttccattatt tatgctttga atggcattgt gttactagtc atagtaagta
    16921 aattgggtat tccaggtgat ttaggattag attttatagt agctattgta gtcaatacaa
    16981 ttttgttagt cctgttttat tttctattat cttacatttt ctatttatac aaattgaaaa
    17041 gtggcttggt atttggtatt ttagtagctt tactactctt tatccctaat atattaaata
    17101 cgatgatgat gaatactagt aatgatttgt ttatcaaagc aattgaactt cttccttttt
    17161 attctttacc tgtatttgtg acttcaaata cgatgtctat tagtcagtat cttgtggtaa
    17221 tcactacaat cattttattg tactttttca ctctcaagaa aagcaagaag tattcatttt
    17281 agtttcattt agtattattt tgcataccta aaatacaata aaaaaatcag tcatcttggt
    17341 atgctcctgc tttcactatt caacacgttt ttgacttata ctaggctcat ttccaaaagc
    17401 attatataat agtgatatga aaccaactaa actaaacaag aaatataagc aataaaaact
    17461 cgtttaaaag attctactaa agctaatact aaataaaaat aaaagagtaa actaggaagt
    17521 ttatttcaaa caacctaaaa tactgatttt cggctgaaga taatactgga gtgcaaatta
    17581 atggggttat aataaatagc tgatagcttg tgttggtttt ggatttttta agagtagatg
    17641 agtattaaaa ctataaggag gacgaaggtg gctaaaaatt taaaattaaa attagctcgg
    17701 gtagagcgtg atttaacaca aggtcaactg gcagaggctg tcggggtgac acgccagact
    17761 attggtttga tagaggcggg aaaatacaat cccagtctct cgctctgcca gtctatttgc
    17821 agatgtttag ggaaaaccct agaccaacta ttttgggagg aagaagatga aaaatagatt
    17881 ttattattat caattactag acgaaagaga agaacaactg ttcaataaag cgggctctga
    17941 aagtttctat atctgcattg ctttgtcgct cctatcttat atcatttcag tattagcacc
    18001 aagccttttt aattctaata tgctgctaat cgttatcatc atagggacat tttacttttt
    18061 caatcgtgcc cgttatctgg gagtgaccta ctatagtcgt tttcatttta cgattttggg
    18121 ttgttttttc ctaaccttgg ctattacggc tcttttgatg ttgcagaatt atcaattcaa
    18181 catagaaatt tatcagcaca atcctttgaa ttttaaatac ctgtctgctt gggtcattac
    18241 ttatgtcatt taccttccgt gggtctttat tggcaatctt ggtcttaaga gctatggcga
    18301 atgggctcag aaaaaatttg aacaagatat ggatgaattg gagagtggag aatagcttgt
    18361 tactcttttc tcaatccagc taaaatgtga tataatagta ctaatttatt ggaatacatg
    18421 aaagttcttg aaaattttca tgggtttcta gctaaggaag taggaaaagt atgtatccag
    18481 atgatagttt gacattgcac acggacttgt accagatcaa catgatgcag gtttactttg
    18541 accaagggat tcacaataag aaggcggtct ttgaggtgta tttccgccaa cagcctttta
    18601 agaacggcta tgcggttttt gcaggtttgg aaagaattgt gaattatctt gaagacttgc
    18661 gtttttcaga tggtgatata gcctatttgg agtcgcttgg ttatcatggg gcgttcttgg
    18721 attaccttcg caatttcaag ttggagttga ccgttcgttc tgcccaagaa ggggatttgg
    18781 tttttgctaa tgaaccgatt gtgcaggtgg aaggacctct agcccaatgt cagttggtcg
    18841 aaacggctct tttgaacatc gtcaactacc agaccttggt ggcgacgaag gcagctcgta
    18901 ttcgttcggt tatcgaagat gaacccttga tggagtttgg gacacgtcgg gctcaagaaa
    18961 tggatgcggc catctgggga acacgcgcag ctgtgattgg tggcgccaat ggaaccagca
    19021 atgtgcgtgc gggtaagctc tttgacattc ctgttttggg aacccatgcc catgccttgg
    19081 tacaggttta tggcaatgac tatgaagctt tcaaggctta cgctgcgacc cacaaaaatt
    19141 gtgtctttct tgtggatacc tatgacaccc ttcgcatcgg tgtaccagct gccattcagg
    19201 tggcgcgtga gctgggtaat cagattaact ttatgggtgt gcggattgac tctggggata
    19261 ttgcctacat ttctaagaaa gtccgtcagc aactggatga ggctggattt acagaggcta
    19321 agatttatgc ttctaatgat ttggacgaaa atactatcct caacctcaag atgcaaaagg
    19381 ccaagattga tgtctggggc gtgggtacca agctgattac agcctatgac cagccagctc
    19441 ttggggcggt ttacaagatt gttgcaatcg aagatgaaac tggtcagatg cgcaatacga
    19501 ttaagctgtc taataatgcg gaaaaagtgt cgacgccagg taagaagcag gtgtggcgca
    19561 ttaccagtcg tgaaaaaggc aagtcagaag gtgactacat cacttatgat ggtgtggata
    19621 ttagcgacat gacagaaatc aagatgttcc atccgaccta tacatacatc aagaagacgg
    19681 ttcgtaattt tgatgccgtt cctctcttgg tggatatctt caaagaagga atattagttt
    19741 acaacttgcc tagtttgact gacattcagg attatgcccg taaagaattt gacaagttgt
    19801 gggatgagta taagcgtgtg ctcaatccgc agcactatcc agtggatttg gcgcgtgatg
    19861 tatggcaaga taagatggac ttgattgata agatgcgcaa ggaagccctt ggtgaaggag
    19921 aagaagaatg agtttgcaag aaacgattat ccaagagctg ggtgtcaaac cagtgattga
    19981 tgcccaggaa gaaatccgtc gttctattga tttcttaaaa agatatctga aaaaacatcc
    20041 cttcctaaaa acctttgtac tagggatttc tgggggacaa gactcaacct tggcagggcg
    20101 tttggcgcaa ttagctatgg aagaactgcg agctgaaacg ggagacgaca gctacaaatt
    20161 tatcgctgtc cgcctgccat acggagtgca agctgatgaa gcagatgctc aaaaagccct
    20221 agccttcatc cagccagatg tcagcttggt tgtgaatatc aaggaatcag ctgatgccat
    20281 gacagctgca gttgaagcga caggtagtcc tgtttcagac ttcaacaagg ggaatatcaa
    20341 ggcacgttgc cgtatgattg ctcagtatgc ccttgctggt tcccatagcg gagcggtcat
    20401 tggaacagac cacgccgcgg aaaatatcac aggtttcttt accaagtttg gtgacggcgg
    20461 tgcggatatt ctccctcttt accgcctcaa taaacgccaa ggaaaacagc tcttgcagaa
    20521 acttggcgca gagccagccc tttatgaaaa aatcccaacg gcagacctag aagaagataa
    20581 accaggccta gctgacgaag tcgcacttgg agtcacctac gcagagattg acgactacct
    20641 agaaggcaaa acaatcagcc cagaagctca agcgaccatt gaaaactggt ggcacaaagg
    20701 ccaacacaaa cgccacttac ccatcaccgt atttgatgac ttttgggagt aaaaaggtcc
    20761 gggggacctt tttagcttct tgccctgaaa ttaaaaagca agaaaaacct ccactggagg
    20821 ttttcagcct ctcatcttga aataagaaag tgagagaagg tccgggggat cttgaacccc
    20881 gagtttagaa ataagaaaat gaggcagatt cggtaactcg aagagttcga tttcatcgtc
    20941 ttacccctgc aacgatgact aggtttgaaa aagattgcta gagcgcattt caaaccaggc
    21001 agcgactgcg tcaagaaatt agaagacaaa ctcgttttct agctgttact gagttgagtc
    21061 tttttactac gagcatagaa ataaggaagt gaggtagcat catgaaatct atcggtacgc
    21121 aaatattaca gacagaacgt ttgattttaa gaagatttgt ggagagtgat gcagaagcta
    21181 tgtttcaaaa ttgggcttca tccgctgaga atttgaccta tgttacctgg gatccccatc
    21241 ctgatgtcga aatcactcga aactcgattc gcaattgggt tgcttcctat actaatctca
    21301 actattacaa atgggccatt tgtctaaaag aaaacccaga gcaagtgata ggagatatca
    21361 gcatcgttaa gatagacgag gctgatttaa gctgtgaaat cggctatgtg ctaggcaagg
    21421 tttactgggg acatggtatg atgacagagg ccttgaaagc tgtcttggac ttttgtttta
    21481 ctcaagcagg ttttcaaaag gtcagagcac gttatgccag tctcaatcca gcttcaggtc
    21541 gtgtcatgga aaaggctgga atgtcctatc tacaaaccat tgttaatggt gtagagagaa
    21601 aaggctatct tgcggatctt atttattatg gtataagtag ggaagaatgt tgaattctat
    21661 tttctgtttc tatcgaagtc aactatttat tgtaaatata ataattagca ttccaagttt
    21721 atttgaaact ttaaaatagc atattgatta gtacaagaca gatgttctag ttccttcttt
    21781 aatctggttt agtattagtt aaaaaatcgc tttaagcttg taactaagag ggagctaatc
    21841 gactagattc tccagccgaa caggtggtaa tgtacttttt atagtgtaat cctagctgtt
    21901 gttaaattta aaatagaatc ctctatcgag ttagggaatt aaattcaacc aattttattc
    21961 atgttttttc tatcaaatta tctaatatta aaatagtctc attctgatga gaaaactatt
    22021 ctatttatac tgcatagttg tataaggaat gatgaaagat gagtgaaagt tatcaagttg
    22081 gaatgtttgt atctaaatat attagcatgt atttagataa gatgtctgca atcctttata
    22141 tatgagattg attacgatat agttaaagtg ttagttcaat agtaaatata tcattctaag
    22201 tctattttat atataaagta tattgtttaa cgtttgatag aaaagatgct atactagaag
    22261 taggatgtaa tggcaaaatc taatactaat aagcgctatg caatacgtaa actcggaaag
    22321 atttttggtt ctgcggtaat cgggctaact ttatttttag gaggaatctg aatacaagtt
    22381 ttgttcatgc tgctgatggg attcaatatg tcagagatga tactagagat aaagaagagg
    22441 gaatagagta tgatgacgct gacaatgggg atattattgt aaaagtagcg actaaaccta
    22501 aggtagtaac caagaaaatt tcaagtacgc gaattcgtta tgaaaaagat gaaacaaaag
    22561 accgtagtga aaatcctgtt acaattgatg gagaggatgg ctatgtaact acgacaagga
    22621 cctacgatgt taatccagag actggttatg ttaccgaaca ggttactgtt gatagaaaag
    22681 aagccacgga tacagttatc aaagttccag ctaaaagcaa ggttgaagaa gttcttgttc
    22741 catttgctac taaatatgaa gcagacaatg acctttctgc aggacaggag caagagatta
    22801 ctctaggaaa gaatgggaaa acagttacaa cgataactta tgatgtagat ggaaagagtg
    22861 gacaagtaac tgagagtact ttaagttaaa aagaagactc tcaaacaaga gttgttaaaa
    22921 aaggaaccaa gccccaagtt cttgtccaag aaattccaat cgaaacagaa tatctcgatg
    22981 gcccaactct tgataaaagt caagaagtag aagaagtagg agaaattggt aaattactct
    23041 tactacaatc tatattgtag atgaacgtga tggaacaatt gaagaaacta cttctcgtca
    23101 aattactaaa gagatggtaa aaagacgtat aaggagaggg acgagagaac ctgaaaaagt
    23161 tgttgttcct gagcaatcat ctattccttc gtatcctgta tctgttacat ctaaccaagg
    23221 aacggatgta gcagtagaac cagctaaagc agttgctcca acaacaggct ggaaacaaga
    23281 aaatggtatg tggtattttt ataatactga tggttccatg gcaacaggtt gggtacaagt
    23341 taatggttca tggtactacc tcaacagcaa cggttctatg aaagtcaatc aatggttcca
    23401 agttggtggt aaatggtatt atgtaaatac atcgggtgag ttagcggtca atacaagtat
    23461 agatggctat agagtcaatg ataatggtga atgggtgcgt taacagattc ctccctgcga
    23521 caaaattgat aatagtatgt ctgaatatat aattatatat aaaaagctat agataaggtc
    23581 atcttatagc gactataaaa aagtgaacaa gcctagtctt ctgtacatta gaattcagat
    23641 ttgttcactt tttgtttaat actcaatgaa aatcaaagag caaactagaa aactagtcgc
    23701 aggttgctca aagtactgct ttgaggttgt agatagaact gacgaagtca gtcacatata
    23761 taatccaagg tgacgttgac gcggtttgaa gagatttttg aagagtataa gtctttgatt
    23821 ttgagactaa ggagagtcag ggtcaaagta gtgaatgatt ctgaaataac tcataatagt
    23881 ctcttgagag gacagataag agtaacaaat atggtgctac tcatgtgtct tgcattttga
    23941 tttacaaaca gcgaagaaaa tataggaagc tgaaataaaa tatagatgaa tcaatttgga
    24001 gagtcaacgc aatctatggc aatattttcg aagctagggg gaagcatttt aatttcaatg
    24061 tactaggcgt cttctacagc tagctagagt ttcaattgta gatgttcttt gaaataatat
    24121 cttagcgatt tattggtatt agaagaatta gagaaattct ttctcaataa ataaacatgg
    24181 cgtcaccaaa actgaagaag cggtagtgtt cttggatggc atggtggtag gcatctaaga
    24241 ctaattcacg gcctgcaaag gcagaaacca acatgaccag agttgatttt ggcagatgga
    24301 agttggttga gaaggcatcc acgaccttcc actcataccc aggtttgata aagatattgg
    24361 tccaaccaga atctgcttgg atttgcccat caaacttgga accaatagtt tccaaggtgc
    24421 ggatagaagt ggttccgaca gcgatgacgc gaccaccatt ttctttgaca gagcgaaggg
    24481 tggcagcagc ttcctcagaa agttgataga actctgagtg catttcgtgt tcgtccagat
    24541 tatccacaga aacaggtcta aaggttccga gtccgacatg gagagtcaga tagactagat
    24601 gaacaccctt agcttggatt tctgccagca gttctttggt gaagtgaaga ccagcagtcg
    24661 gtgctgcagc agagccgctt tccttggcgt agacggtttg ataacgttca cggtcatcta
    24721 atttttcgtg gatataaggt ggcagaggca tttctcccag actttccaag acttctagga
    24781 aaattccttg gtattcaaag cggacaatgc gtcccccgtg ggtcaattct tctgtaacga
    24841 cagcgctgag gcggccatca ccaaagctga tacgagtacc gaccttgagg cgtttggcag
    24901 gtttagccag aacttcccac tcgtctccac tagtgttctt aaggaggaga agttccacat
    24961 gacctcctgt ctccactttt tgaccataga ggcgggcagg gagaactcgg gtgtcgttca
    25021 tgacaagggc atcaccaggt tccagcatat caataataga gtggaagtgt ttatcttgca
    25081 tttctcctgt ctcacggttg acgatgagga gtttggaggc atcacgtttt tcaaggggcg
    25141 tttgggcaat caattcctct ggcaagtgga aatcaaaatc agctgtattc atatatttgt
    25201 tcattctttc taagttctaa tcctatccat tataacacgt ttcaagtttg gacgctcttt
    25261 tttttagaaa ttaaatcgtt ttcacttgac aaaaattggt ctataccata taatagatat
    25321 agacagaaat ggaggatgaa aagatgaaag ttattaaagt tgaaaaccaa gttcaaggtg
    25381 gaaaagttgc ttttgagatt ttgaaggaaa aattggctaa tggagctcaa actctaggac
    25441 ttgcgacagg aagtagccca cttgaatttt acaaggaaat tgttgagagt gaccttgatt
    25501 tttcaaatct aaccagtgtc aaccttgatg agtatgtggg ccttgatggg gacaatccac
    25561 agtcttatcg ttacttcatg caagaaaact tgttcaacca aaaaccattt aaagaaagtt
    25621 tcttgcctcg tggtgttaag gacaatgctg aagctgaagt tgaacgctac aaccaaattt
    25681 tggctgacca tccagttgac ctccaaatct tgggaatcgg tcgcaatggg catatcggct
    25741 ttaatgagcc tggtactcca tttgacagtc aaacgcatct agtagaactt gaccagtcta
    25801 ctatcgaagc caatgcacgc ttctttgcca agattgaaga cgtcccaacc caagctattt
    25861 caatggggat taaaaacatt ttggatgcca agtctattat tctttttgct tacggtgagt
    25921 cgaaagcaga agccattgcc ggaacagtat ctggcccagt gactgagaac ctacctgcaa
    25981 gtagccttca aaatcaccct gatgtaacca tcatcgcaga tgctgaagcg cttagcttac
    26041 tcgaaaaata aaaaagcaat gttctattga acgctttcaa ctcttgtata aatggaagaa
    26101 aaaatcaaaa ttaaaccgca tttttgcttg acaattattc cttttacgtg tagaatggaa
    26161 tagatattga acttgaaggg agtgaaaaaa atgtctaaaa cagtagtacg taagaatgaa
    26221 tctcttgacg acgcacttcg ccgtttcaaa cgtgcggtta ctaaagctgg tactcttcaa
    26281 gaaacacgca aacgtgaatt ctatgaaaaa ccttctgtaa aacgtaaacg taaatcagaa
    26341 gtagctcgta aacgtaaaaa attctaattg aaatgaaagg ctagagaaat ctagtccttt
    26401 ttcttttaaa taaatactcc aaagcctgca aaaatctgaa acttcctcct acaatttgat
    26461 ataatagaga gaagaactca tttgaaggag gaaatgatgt cggttttagt aaaagaagtg
    26521 attgaaaagc ttagactaga cattgtctat ggtgaaccag aattgcttga aaaggaaatc
    26581 aatacagcgg atattacgcg acctggtctt gaaatgacag gctattttga ctactataca
    26641 ccagagcgga ttcaactttt ggggatgaag gagtggtctt atctgatcag catgccttcc
    26701 aacagccgtt atgaagtttt gaaaaaaatg tttctacctg agacaccagc agtcattgtt
    26761 gcccgtggtt tggtggttcc agaggagatg ttaaaggctg ctagagaatg taagattgct
    26821 attttaacca gccgtgcagc taccagtcgt ttatctggag agttatctag ctatctggat
    26881 tctcgtttgg cagaacgtac cagtgtgcac ggtgtcttga tggatattta tgggatgggc
    26941 gtcttgattc agggagatag tggaattggt aagagcgaga caggtcttga gcttgtcaaa
    27001 cgtggtcacc gtttggtagc cgatgaccgt gtcgatatct ttgccaagga tgagattact
    27061 ctctggggtg aaccagctga aattttgaaa cacttgattg aaattcgtgg ggttggtatt
    27121 atcgatgtta tgagtctcta cggtgcgagt gctgtcaagg attcttcaca ggttcagctt
    27181 gctgtctatt tggaaaatta cgatacacat aagacctttg atcgtcttgg aaacaatgca
    27241 gaggaacttg aagtttctgg cgtagccatt cctcgtattc gtattccagt taaaacaggt
    27301 cgtaatatct ctgttgtgat tgaggcagct gccatgaatt atcgtgccaa ggaaatgggc
    27361 tttgatgcga cccgtttgtt cgacgaacga ctgacaagtc tcatcgctcg aaatgaggtg
    27421 caaaatgctt gatccaattg ctattcaact aggaccccta gccattcgtt ggtatgcctt
    27481 atgtattgtg acaggcttga ttcttgcggt ttatttgacc atgaaagaag cacctagaaa
    27541 gaagatcata ccagacgata ttttagattt tatcttagta gcctttccct tggctatttt
    27601 aggagctcgt ctctactatg ttattttccg atttgattac tatagtcaga atttaggaga
    27661 gatttttgcc atttggaatg gtggtttggc catttacggt ggtttgataa ctggggctct
    27721 tgtgctctat atctttgctg accgtaaact catcaatact tgggactttc tagatattgc
    27781 ggcgcctagc gttatgattg ctcaaagttt ggggcgttgg ggtaatttct ttaaccaaga
    27841 agcttatggt gcaacagtgg ataatctgga ttatctacct ggctttatcc gtgaccagat
    27901 gtatattgag gggagctacc gtcaaccgac tttcctttat gagtctctat ggaatctgct
    27961 tggctttgcc ttgattctga tttttagacg gaaatggaag agtctcagac gaggtcatat
    28021 cacggccttt tacttgattt ggtatggttt cggtcgtatg gtcatcgaag gtatgcgaac
    28081 agatagtctc atgttcttcg gacttcgagt gtcccaatgg ctgtcagttg tccttatcgg
    28141 tctcggtata atgatcgtta tttatcaaaa tcgaaagaag gccccttact atattacaga
    28201 ggaggaaaac taaatgttag aagttgcata tattcttgtt gccctagctt tgattgtctt
    28261 tttggtctat ctgatcatta ctgtacaaaa gcttggtcgt gtcatcgatg aaacagaaaa
    28321 gacgattaaa accttgactt cagatgtgga tgtgaccttg catcacacca atgagttgtt
    28381 ggctaaggtc aatgtcttgg cagatgatat caatgtcaag gtggctacga ttgatccact
    28441 cttcagtgct gttgcagatt tatctctatc tgtttcagac ctcaatgacc atgcgcgtgt
    28501 cttgagcaag aaagcttcat cagctggttc aaaaacactc aagactggtg caagtctgtc
    28561 agctcttcgt cttgcaagta aatttttcaa aaaataaaaa aggagaatcc ttatgggtaa
    28621 attatcctca atccttttag gaaccgtttc aggtgcagct cttgccttgt ttttaacaag
    28681 tgataagggc aaacaagttt gcagtcaggc tcaagatttt ctagatgatt tgagagaaga
    28741 tccggagtat gccaaggagc aagtctgtga aaaactgaca gaagttaagg agcaggctac
    28801 agattttgtt ctgaaaacaa aagaacaggt tgagtcaggt gaaatcactg tggacagtat
    28861 acttgctcaa gctaaatcct atgcttttca agcgacagaa gcatcaaaaa atcaattaaa
    28921 taatctcaag gaacaatggc aagaaaaagc cgaagctctt gatgactcag aagagattgt
    28981 gattgatata acagaagaat aaaccatcac catctccgaa cggactatgt atctggggat
    29041 ggtgattttt atctggaatc tagtctttgt ggtataataa ttactatgca gaaaaaacca
    29101 acgtcagcct atgtgcacat cccattttgt acccagattt gttattattg tgatttttca
    29161 aaggtcttca tcaaaaatca gccagtcgac agctatttag agcatctgct ggaagagttt
    29221 cgttcttatg atattgaaaa gttgtcaacc ctttatatcg gtggtggaac accgacagcc
    29281 ctgtcggctc cgcaactgga ggttttactg aatggcttga ctaaaaactt ggacttgtct
    29341 gtcttagaag agttgaccat tgaagccaat ccaggcgatt tggatgcgga taagatagct
    29401 gttttgaaaa attcggctgt caatcgtgtt tcgctaggtg tccagacctt tgatgataag
    29461 atgttgaaaa agattgggcg cagtcatttg gagaaggata tttatgaaaa tatcgatcgc
    29521 ctgaaactgg ctggttttga caacatctcc attgatttga tttatgctct gcctggtcag
    29581 accatggagc aagtaaagga aaatgtggct aaagccattg gactggatat tccccacatg
    29641 agtttgtata gtttgatttt agaaaaccat acggtcttta tgaaccggat gcgacgtggg
    29701 aaattgcctc tgcctaagga ggaactagaa gcggagatgt ttgagtacat cattgcagag
    29761 ctggagcgag cgggttttga gcattatgag atttctaatt tctccaaacc cggctttgaa
    29821 agtcgtcaca atctcatgta ctgggacaat gctgaatact atggtattgg tgcaggggca
    29881 tctggttatg tcaatggagt acgctataaa aatcatggtc ccattcgtca ttatctcagt
    29941 gcggttgagg aaggcaatgc ttgtattaca gaagatcacc tgagtcaaaa ggagcaaatg
    30001 gaagaagaaa tgttcttggg actccgcaag aaatccgggg tttccatggc gcgatttgag
    30061 gaaaaatttg gacagtcttt tgctggactt tatggagaaa ttgtcagaga tttggttcaa
    30121 caaggcctca tgcagattga gggtgaccac gttcgcatga caaagagagg tctctttttg
    30181 ggagatactg tagcagaacg atttattttg gagtaggatc atgggcttaa cttatcaaat
    30241 gaaaatgaaa attccttttg atatggctga tatgaacggt catatcaaac ttccagatgt
    30301 gattttgctg tcactgcaag tttcagggat gcagtcgatt gaactgggag ttagtgataa
    30361 ggccattttg gaagactata atctggtctg gattatcgca gaatatgata ttgaggtggt
    30421 tcgtttgcct cgttttgcgg aagaaattac catcgaaacg gaagccttga gctacaatcg
    30481 acttttttgc taccgttgct ttactattta taatgaagcg gggcaggagc tcatccatat
    30541 gatggcgacc tttgttctca tggaccgcga cagtcgaaaa gtccatgctg ttgaacctga
    30601 gattgtggct ccttaccagt ctgattttga taaaaaactt atccgtggac cgaagtatga
    30661 gtccttggaa gagctgatca gcaaggatta ccatgttcgt ttttacgact tggatatgaa
    30721 tggtcatgtc aataacagta aatacttgga ctggattttt gaggtcatgg gagcggattt
    30781 tttgacccac tatattccca agaaaatcaa cctcaagtat gtcaaggaag ttcgaccagg
    30841 tggggtgatt acatcggctg ttgaacggac tggactggaa agcaagcatg aaattacaag
    30901 tgatggggtt atcaatgccc aagcaatcat tacttggcaa gaaataaaaa aggcttaggg
    30961 agaaatagat gaaatataaa ggctatttaa ttgatttaga cggaaccatt tataagggga
    31021 aagaccgaat ccctgctgga gagacttttg ttcatgaatt gcaaaagcgg ggcattccct
    31081 atctctttgt aaccaacaat acaactcgca ctccagagag tgttaaggag atgttggctc
    31141 agaattttaa tatcgatacg cccctatcga ctgtctacac agcgactttg gcaaccatcg
    31201 actatatgaa tgatttgggg cttgaaaaga ccgtctatgt cgtcggagaa gcaggactca
    31261 aggaagtcat caaggcggct ggttatgtgg aagacaagga aaaccctgcc tacgtggtag
    31321 ttggtctgga ttggcaagtc gactatgaaa aatttgccac agcaactctt gctattcaaa
    31381 agggtgccca ttttatcgga accaatcctg acctcaacat cccgacggaa cgtggtcttt
    31441 tgccaggtgc tggctcactg attacgctgc ttgaagtagc gacacgagtg aagccggttt
    31501 atatcggaaa accaaatgcc atcattatgg acaaggcggt tgagcactta ggtttggaac
    31561 gtgaagagtt aatcatggtt ggggacaatt atttgactga tatccgggct gggattgaca
    31621 atggcattcc aacactcttg gtgacgacag gttttaccaa ggcagaagaa gtagctggcc
    31681 tgccaatcgc accgacacat gtggtttcta gccttgcgga gtgggatttt gatgaaaact
    31741 aaattgacct tttggggctc tatgctcttt ctcctctccc tctcaatcct tctgaccatt
    31801 tatctggctt ggattttcta tcctatggag attcagtggc taaacttaac gaatcgagtc
    31861 tatctaaaac cagaaaccat tcaatacaat tttcatatct tgatgaatta tctgaccaat
    31921 ccttttagtc aggtcttaca gatgcctgat tttcgttcgt cagcagctgg tctgcaccat
    31981 ttcgcagtgg tcaagaatct ctttcatttg gttcagctag tagctctagt gacactgcca
    32041 agtttctatg tctttgtcaa taggattgtg aaaaaggact ttttgtctct ttatcgaaaa
    32101 agtctcctga ctctagtagt cttacctgtg atgattggac ttgggggagt tttgattggt
    32161 tttgaccaat tctttactct tttccatcaa attctctttg tgggagatga tacatggctt
    32221 tttgatccag ccaaggatcc tgttattatg attttgccag agaccttctt tcttcatgcc
    32281 ttcctcctct tttttgccct ctatgaaagc ttctttgggt atctgtgtct gaaaagtcgt
    32341 aggaagtgaa atgaaagatg tttttaattt gcatatataa aaatatatat cgtttaaaac
    32401 catcgttaag agtgaattaa ccaaatccaa ttgtgtcaat cgttcgcaaa cagcctattt
    32461 ttcttgaaaa aataggcttt ttttctaaaa atccctagtc aagcgcctta tttttttgta
    32521 taatagaagt agcaaagtat agataagaag agaaaagcat gattacacta tttctatcac
    32581 cgagctgtac atcatgtcgt aaggctaagg cctggttaga aaaacataag gttccctttg
    32641 tggaacacaa tattatgacc agtcctttaa caagaaaaga attgcaacac atcctttcct
    32701 tgaccgaaaa tggtactgat gacatcattt caactcgttc aaaaattttt caaaaattga
    32761 atattgatgt agagagtatt tcggtatcgg aattgcttca tttgattgag cagtatccta
    32821 gtcttttgcg tcgtccaatt attattgatg ccaagcgtat gcaaatcggt tttaatgaag
    32881 atgagattcg tgcttttctc cctcgtagtt atcgtaagca agaactaaaa gaagcaagaa
    32941 tgagagctgg tattagttaa tgaacaaaca gtatagttac ccactagatt tgtcgtggag
    33001 cactgaagaa cttgcttcag tgctttcttt ttttaatgat gttgaagctg cctatgaagg
    33061 caaagtagag gctaaaaagt tactggactc ctataaggga ttcaaagcgg tcgtgccaag
    33121 caagagcgaa gagaaacgtt tgggacgaga atttgaaacg gttagtggct attcacttta
    33181 ccgagcagtt caggctgcca aagaaaaagg ggaaggaaag atttctcttg gaaagtaaat
    33241 ttgaatttgc taaagagctt gttaagaaag caggccagta cattcttgac catatgcagg
    33301 aagacttgcg tgttgaaacc aagtcctctc caacagattt ggtgaccaga ctggacaaag
    33361 aagttcagga actcttggtt ggtgagattt tgtcccgtta tcctgaggat aagatttgtg
    33421 ctgaagaagg ttgtctgcga gcctcggttc aagagggcaa ggtttgggtc attgatccca
    33481 ttgatggtac caataatttt gtagcccagc aggaagattt tgctgttatg atggcttatt
    33541 ttgaaaatgg tcagggacag tttggtctga tttatgatgt ggtcaaaggg gattgttacc
    33601 acggtggtgg ggaatttcca gtttgtctaa atgataggcc cctagctcct tttaaaacta
    33661 aaccacttgg agattttctc attgcaggga atagtggtat gctggaaacc aatgaatggg
    33721 ggctggctga tttgagccga tcggttcttg gtgttcgtgt ctatggaagt gcggccatta
    33781 gttttgccaa gattttgtca gggcgtttgt tgacctatct cacttatctg caaccatggg
    33841 attatgccgc agctagtatt ttaggggaaa gtctgggcta tcgggttgtg accctttttg
    33901 gtgaagctcc tgattttcaa accagacagc cggtcatgat ggtgcctctt gagatgcagg
    33961 aggaaattca gtcctatatt tacgaaagga aaagaactta aatgcaattt ccagaaggat
    34021 ttgttgaaaa atataaagag atactaggag atgaggcaag agattttctt gcctcttttg
    34081 aggaggaagc ggtttcggcc tttcgggtca atcccttaaa agaagagcaa ctttcctttt
    34141 ctgatgccat tactcaaacc ccttggggcc actatgggaa ggtttcaggg aaatcgcctg
    34201 agcatgctac aggtttagtt tattcgcaag aacctgctgc tcaaatggtg gctcaagtag
    34261 cccaacccag tcctggtatg aaggtcttgg acttggctgc tgcaccgggg ggcaaatcaa
    34321 ctcaactggc agcctatcta gcaggggagg ggctacttgt ttccaatgaa atttcaagca
    34381 aacgggctaa gattttggtt gaaaacatgg agcgttttgg agcgacaaat gtcgtggtga
    34441 ccaatgaatc tgccgactgc ttggtcaagg tctttaaagg ctattttgac ttaatcgttc
    34501 ttgatgcccc ttgctctggt gaaggaatgt ttcgtaagca acctgatgct atggactatt
    34561 ggagcttaga ttatccgagt caatgtgcta gcttgcaaag agaaattctg gaggatgcag
    34621 tgaccatgtt agctgaaggt ggtcgtctgg tttattcgac ctgtacctgg gcacccgagg
    34681 aaaacgaaga gattgtcaat tggttgctgg aagagtatga ttttgacttg ttgccagtag
    34741 agcatatcaa tggaatggta gctggtattg acctgccaga aacggctcgg atgtaccctc
    34801 atcagtttaa gggagagggt cagtttgttg cccatctaca gtttaagggt aacaatccag
    34861 ctcctaaatt taaggcaagt aagagtaacc tcagccgtga acaagttgcc ttgtggcagg
    34921 aatttgccca aaaccatttg aaggtcaatc taccgggtat cttgcagact tttggagacc
    34981 agctttatct cttgccagaa cttttgccag atttagggaa gctcaagatt gctcgcaatg
    35041 gactgcatct gggcactttt aagaagaaac gctttgagcc cagtttcgct cttggtttag
    35101 ccttgaaacc gagtcaggtc gaacagtcgg ttgaaattgg ccaagaagcg tttgtcaagt
    35161 atgcggctgg agaaatcgtt cagctggcag aaagtctgcc aaatggttgg taccaagttt
    35221 tggttaaagg caatggcttg ggctttgcaa aggttactgg aaatgttttg aaaaattatt
    35281 ttccaaaagg cctcagattc aaatgaaaat gctagtcaaa tatcttattc tatgttatag
    35341 tgaaagtatg gattttttta gtaggatgat tcttgatatc ttgattgcca ttacatgtag
    35401 ttttactact caatgaaaat caaagagcaa actaggaagc tagccataga tagctcaaaa
    35461 cactggtttg aagagatttt caaagagtac aagaagttta gttattagcg ttcttaccgc
    35521 ttgtaaacta gatttctcat aaaatagaat cttttccttt tagttgtaaa ctagtctggg
    35581 agagtagaga ggtttgagat acctttctag cttttggatt atcatctaag gagagtaatt
    35641 tcccttgcat taaaaagggg aaaaagagac acgaaatgac tataatgggt gacaatgggg
    35701 gaagggatag acaagagatt ttatccacat atgaaaaaag gaggttagga aagagtaata
    35761 tagcctatat tatataaata atcaattgcg cagaaatttg gtaagaattc atgcgtcaac
    35821 tcataaagaa ctacttaaaa aattcacagt attcataatt attttcgagg agaaaaacag
    35881 tgaaaaaaag aaaaaagctt gctctgtctc ttatcgcttt ttggctgacg gcttgtttag
    35941 taggctgtgc tagctggatt gatcgtggag aatccataac ggctgttggc tcaactgcct
    36001 tgcaaccctt ggttgaagta gcggcagatg aatttggcac gatccatgtt ggaaaaacgg
    36061 tcaatgtcca agggggaggt tctggtacag gcttgtccca ggttcagtct ggggcagttg
    36121 atataggaaa ctcagatgta tttgctgagg aaaaagacgg aattgatgct tctgctcttg
    36181 ttgaccacaa ggtcgcggta gctggcttgg ctctgattgt caataaggag gttgatgttg
    36241 ataacctaac gacagagcaa cttcgtcaaa tcttcatagg tgaggtaacc aattggaaag
    36301 aggttggtgg taaggactta cccatctctg ttatcaatcg ggcagccggc tctggctctc
    36361 gtgctacctt tgatactgtc attatggaag gtcagtctgc catgcaaagt caggagcagg
    36421 attcaaatgg agcggtaaaa tcaatcgtat caaaaagtcc aggagctatc tcttatttat
    36481 ctcttaccta tatagatgat tcggtcaaaa gcatgaagtt gaatggctat gacttaagtc
    36541 cagaaaatat aagtagcaat aattggcctt tgtggtctta tgagcatatg tatacattgg
    36601 ggcagcccaa tgagttggct gcagaatttc tcaattttgt tctctcggat gagacccaag
    36661 aagggattgt caaaggattg aagtatattc cgattaagga aatgaaggtt gaaaaagatg
    36721 ctgccggaac tgtgacagtg ttggaaggga gacaataatg aatcaagaag aattagctaa
    36781 gaaaatgttg cttccatcaa agaattctcg tctggagaaa ttaggaaaag gtttgacctt
    36841 tgcctgtctt tctttgatag tcatccttgt ggccatgatt ttggttttcg tagcgcaaaa
    36901 aggcttgtcg accttctttg tcaatggtgt gaatatcttt gactttcttt tgggaggaac
    36961 ttggaatcct tctagtaaag aatttggtgc ccttcctatg attttgggtt cctttatcgt
    37021 taccattctc tcagccctta tcgcaacacc ctttgctatt ggtgcagcag tttttatgac
    37081 cgaagtatca ccaaaagggg cgaagatttt acaaccagct attgaactcc tggttgggat
    37141 tccttcagta gtgtacggat ttattggctt gcaagtcgtc gttccctttg ttcgcagtgt
    37201 ctttggtggg actggttttg ggattttgtc agggatttcc gtcctctttg tcatgatttt
    37261 gccgaccgta acctttatga caacggatag cttgcgtgcg gttcctcgtt attatcgtga
    37321 ggccagtttc gctatgggag ccactcgctg gcagactatc tggcgtgtaa tcttgaaggc
    37381 ggcccgttct ggtattttca ctgcagtggt ctttgggatg gcgcgtgcct ttggtgaggc
    37441 tttagctatc cagatggttg tcggaaactc agctgttatc ccaacttcct tgaccacacc
    37501 agctgcaact ttaacttcta tattaactat gggaattggg aacactgtca tgggaactgt
    37561 aaataataat gttctctggt cactggcctt ggtactgctc ttgatgagtt tagtttttaa
    37621 cagtgtgatt aaattgatta cgaaagaaag aggaaagaaa aattatgcgc gctaagaaat
    37681 tagataaact tgcaacagct gtcctctata cgattgctag catcattgtg acaatcttgg
    37741 cttccttgat tctctatatc ttggttcggg gcttgcccca tatctcttgg tctttcttga
    37801 ctggaaggtc ttctgctttt caagcaggtg gtgggattgg cattcagctt tacaattcct
    37861 ttttcctatt ggtcattacc ttgattattt ctgtacctct ttctatggga gctgggattt
    37921 acttggctga atatgctaaa aaaggtcctg ttaccaactt tgtgcggact tgtattgaaa
    37981 tcttgtcctc tttaccatca gtggtggtgg gtctctttgg ttacttgatc tttgtagtcc
    38041 agtttgagta tggattttca atcatttcag gtgccttggc cttgacagtc tttaacttgc
    38101 ctcagatgac gcgtaatgta gaagatagtt tgaaacacgt tcaccatacc caacgtgagg
    38161 ctggtctggc tcttgggatt tctcgctggg agacagtgat tcatgttgtt attccagaag
    38221 cgcttccagg tattgtaacg ggtgtcgtct tggcatctgg tcgtatcttt ggcgaagctg
    38281 cagctctgat ctatacagca gggcaatcgg cgccagctct tgactggtct aactggaata
    38341 tcctcagtgt gactagcccc atctctatct tccgtcaagc agaaaccttg gctgtccata
    38401 tctggaaagt caatagtgaa ggcactattc cagatggaac cattgtatca gcaggttctg
    38461 ccgctgtgct cctgatcttt atcctgattt ttaactttgg agctcgtaag ttcggaagct
    38521 atctacacaa gaaattaacc gctgcctaaa ggagaagcca tgtcaacata taattgggat
    38581 gagaagcata tccttacctt tcctgaagaa aaagtagccc tttctactaa ggatgtccat
    38641 gtttactatg gtaaaaatga atccattaag gggattgata tgcaatttga aagaaataaa
    38701 attacagctt tgattggtcc gtcgggatcg gggaaatcta cctacttacg cagtctcaat
    38761 cgcatgaatg atactattga tattgctaaa gtaactgggc agattctcta tcgtggaatt
    38821 gatgtcaacc gtccagaaat caacgtttat gaaatgcgta aacacattgg aatggttttt
    38881 caacgcccca atccatttgc taagtcaatt taccgtaata ttacctttgc gcatgaacgt
    38941 gctggagtta aggataagca agtcctagat gaaatcgtag aaacctccct tcgtcaggct
    39001 gccctctggg atcaggttaa agacgatctc cacaagtcag ccttgacctt atcaggtggt
    39061 cagcaacaac gtctctgtat cgctcgtgcc atctctgtta agccagatat cctcttaatg
    39121 gatgagccag cctcagcctt ggatccgatt gcgaccatgc aactagaaga gaccatgttt
    39181 gagctcaaga aaaactttac catcatcatt gtaacgcata atatgcagca ggctgctcgt
    39241 gcaagtgact atacaggctt cttttacttg ggtgatttga ttgagtatga caagactgca
    39301 actattttcc aaaatgccaa gctacagtcc accaatgact atgtatctgg tcactttggt
    39361 tagaaaggaa accgtatgac agatgcgatt ttacaggtat cagacctgtc cgtttattat
    39421 aataaaaaga aggctttgaa tagtgtttcc ctatctttcc aacctaagga aattacagcc
    39481 ttgattggtc catctggatc agggaagtca accctcctca agtctctcaa ccgcatggga
    39541 gatctcaatc cagaggtgac cacaactgga tccgtggtgt acaatggtca caacatctac
    39601 agtccgcgta cagatacggt tgaattacgt aaggaaatcg gaatggtttt ccaacaacct
    39661 aatcctttcc ctatgactat ctatgagaat gttgtctacg ggcttcgtat caatggaatt
    39721 aaggataagc aggttctgga tgaagccgta gaaaaagcct tgcaaggtgc ctctatctgg
    39781 gatgaggtca aggatcgtct atatgattca gctattggat tgtcaggtgg tcaacagcag
    39841 cgtgtctgcg tggcccgtgt cttggcaact agtcctaaaa tcatcctctt ggatgagcca
    39901 acttcggctt tggatccgat ttcagctggt aaaattgagg aaaccttgta tggtctaaaa
    39961 gacaagtaca ccatgcttct ggtaacccgt tccatgcagc aagcttcacg tatctctgat
    40021 aagacaggat ttttcctaga tggagatttg attgaattta atgataccaa gcagatgttc
    40081 cttgatcccc aacacaagga aacggaagac tatattacag gaaaatttgg ataaggagat
    40141 gaaagatgtt acgatctcaa tttgaagaag atttagagaa attacataac cagttctacg
    40201 ctatgggaca agaagtgctc tcacaaatca atcgtacggt acgtgctttt gtcacgcatg
    40261 accgtgacct ggcaaaagag gtcatcgaag atgatgcaga agtaaatgaa tacgaagtga
    40321 aactggaaaa gaaatcattt gaaatgatcg cactccaaca accagtctct caagatttgc
    40381 gtacagtctt gactgtcctt aaggctgtat cagatgtgga gcgtatgggg gatcacgctg
    40441 tagccattgc ccaggcaacc atccgtatga agggggaaga acgtattcca gctgtagagg
    40501 aagaaattaa aaaaatggga cgtgaagtta aaagcgttgt tgaagcagca cttgatcttt
    40561 atcttaatgg ttctgttgac gacgcatacc gggtggcctc catggatgag caaattaacc
    40621 actattttga aactatccgt gaccttgcga ctgaagagat taagaaaaat ccagaagcca
    40681 ttgttacggg tcgtgattat ttccaagtta tttcctactt ggagcgtatc ggtgactatg
    40741 ctaaaaatat ctgtgaatgg gttgtctact ttgaaacagg taagattgtc gaactataaa
    40801 atagtttaat tctgtataaa aaggagcttg aaatcaactg atggctcctt tttttgaacg
    40861 aaaaaatatt tttgagataa aaatttaaaa aacacttgac aagtaacttg gatatcgtta
    40921 taattataca aaattaacag agaggttgtt tatttatgaa atcaaaaaaa tggatatttg
    40981 ttttatgtaa ttttcttgca agtttcttct tagtagcttg ccagtcaggt tctaatggtt
    41041 ctcagtcagc tgttgaggcc attaagcaaa aggggaaatt agttgtggca accagtcctg
    41101 actatgcacc ctttgaattt caatcattgg ttgatggaaa gaaccaggta gtcggtgcag
    41161 acatcgacat ggctcaggct atcgctgatg aacttggggt taagttggaa atctcaagca
    41221 tgagttttga caatgttttg accagtcttc aaactggtaa ggctgaccta gcagttgcag
    41281 gaattagtgc tactgacgag agaaaagaag tctttgattt ttcaatccca tactatgaaa
    41341 acaagattag tttcttggtt cgtaaggctg atgtggaaaa atacaaggat ttaactagcc
    41401 tagaaagtgc taatattgca gcccaaaaag ggactgttcc agaatcaatg gtcaaggaac
    41461 aattgccaaa agctcaatta acttccctaa ctaatatggg tgaagcagtc aatgaattgc
    41521 aggctggaaa agtagatgct gttcatatgg atgagcctgt tgcacttagt tatgctgcta
    41581 aaaacgctgg cttagctgtc gcaactgtca gcttgaagat gaaggacggc gacgccaatg
    41641 ccgttgctct tagaaaaaat agtgatgatt tgaaagaagt ggtagacaag gtcatccaaa
    41701 aacttaagga tgaaggaatt taccaaagct atcttgaaaa agcagcaagt ctaactgaag
    41761 ttgaagaata agaaaaagca gagttggatg tcattccaat tctgctttta aatagtttaa
    41821 aacattttcc agattgtcta gggacacctt ggcaaattga taaggacagg tacttaaata
    41881 ggcctcttca aagaagtcca agcccggttg actgtgtttg agactggcga ttttaggata
    41941 ctgtctcagg tctagcaata aaccatcgtg taggggataa tgaggaaggg gacaaggtgt
    42001 tttagttatc ctttcctcga tttgtttttg gtaagattca tgattggtca agcgagccaa
    42061 acgatttttt tcaaacaatt gactgtcaat atagagtgac agggcctttt gcataatgag
    42121 gttgctgtcg tagtctagga tatttttgta ggccacaaat gcttctttga tagcatttgg
    42181 aagaatgagt gctgtaatac gaagggcagg aaaaaggctg gtcgagaagg acttgatata
    42241 aatgacatgc tcctctgtat caagatagtg gaaggtttgg cccttcttgg agtccaaatc
    42301 acccagataa tcgtcttcta cgatatagac atcatacttg gcagctaagt taagaatgga
    42361 tcgtttgtct tgctcagaat aggaatgtcc cagaggatag tgaaatcggg gaatggtgta
    42421 gaaaaactta atttttcctg ttttgaagtg gccttccagc tcctccaagt caatcccatc
    42481 aatgcctcgt tcaatcgttt gatagtccag cccctgtgca atcaagaggc gattcatccg
    42541 atggtaggtt ggctgttcca ccaagatttc cttggcttgt ctaggaaagg atatttgaga
    42601 gaggataaat aaggcttgtt gggttccaga agtcagtact agttggttag ccttgcagta
    42661 gagagcttgc tcaaagagga gtttgtgaat ggactgtctt aggtcttcta atccttcttg
    42721 attgtcatag tagttgaaga ggtagttttc tcgtccaatc aaggtttcat tgacacagag
    42781 tcggaaatcg tcataggcac tggcatgttc gtcggtaacc tcgatttcta ggtcttgatg
    42841 ttgcccttgt tctaggacat agtagccgct ctggggcttg gcatagaggt attgttcgtg
    42901 ccgtaattcc agcagggctc gttgaatggt gtccttgctg cagtgaaagt caaggctcag
    42961 ttgacggata gaaggcaggc gactacccgt cggaaatcgt tcagactcga taccattttt
    43021 cagataggaa acgacctctt tgtacttgct ttgtttcttc attccagacc tcccttgatt
    43081 ttgttacatt gtaccctttt ttttccttct tggcaatgtc tagagcgttt ctctcgttca
    43141 catctagggg caaatgtggt atacttagga gtaagattta tagaataaca gacaagaaag
    43201 tgaatggata agaacgtgca ggaaccagtg aaattatttc aatacaatac tcttggagcc
    43261 ttgatggctg gcctttatgg tggtactatg acagtaggag aattgctaga acatggtgac
    43321 cttggtttgg gaaccttgga ttccattgat ggggaattga ttgtcttgga tggcaaggct
    43381 tatcaggcca aagggtcagg agaccagcca gaaattgtgg aagtgtcacc agatgccctt
    43441 attccttacg ctgcagtggt accgcatcag gcagaggtca ttttccgcca gcgctttgag
    43501 atgacagaca aggaattgaa agaacgaatt gagtcttatt atgatgggga aaatcttttc
    43561 cgctctatca agattcgggg ggaattttca catatgcatg tgcgtatgat tcctaagtca
    43621 acacccgata ccaagtttgc tgatgtcgca acccatcaac cggaatatag tcgtgacaat
    43681 gttgcgggga ctattgttgg tttctggacg cctgagattt tccatggggt cagtgtggca
    43741 ggctaccatc tgcacttcat atcagatgat ttgaccttcg gtggacatgt catggatttt
    43801 gtcatcaagg aaggcattat cgaggtggga gcagttgacc agttggacca acgtttccca
    43861 gtccaagacc gtcaatactt gtttgctaag ttcaatgttg acgagatgaa aaaagatatt
    43921 gaaaaggcag aataggagaa gaaaatgacc attcatatca ttattaccat gttgctgttg
    43981 ctagcttttc tgataggaag catttggttt gccaaaaaga aataccagat taatctagct
    44041 gtcttgggct tgggtgcagt cgctttcttt gtctcttcgc agattttgga aaaactggtg
    44101 catatcttga ttttgcaccc tcaaaaagac ggtagtattg ccctcttgca agatcatccg
    44161 cttatctata ttatctatgg cctagccatg gcagcatttt ttgaggaaac ggctcgtctt
    44221 gttttcttca aatggttgga gaaaaagaga agtttggaaa aggcagacgc cttggcctat
    44281 ggactggggc atggtggctt ggagttgatt tttctaggcc ttactagttt actcaatctt
    44341 tacattgttc tttcggcagt tcaaactcag aatccacagg ttatgcaatt actgtctgaa
    44401 aatatgttaa aaaccattca gtcactttcg gtctggcaga tttatttgct tggttttgag
    44461 cgaatcttgg cgcttggttt ccaattactt ttgacagttt gggtttacca agctgttcgc
    44521 cagaagaaat ggatttatct cctagcagcc tatggcttgc atgccttctt tgatctggca
    44581 ccatctcttt tccaagtagg ctggttgaca aatccagtct tggttgaagt gattctagca
    44641 ctggagctcg ttctggttgc ctatggaacc aaggaaatct tttgtaaaaa atcataaaaa
    44701 ggggggaacc tctttttatt atgcaaaatc caaacaaggt atttttatgg tcgtcaaatg
    44761 tctctaaaaa tggtataatg gaatgaattt tgtaaaagga agagtgacat gtctgtaaga
    44821 gaaaaaatgc ttgaaatctt agaaggaatt gatatccgtt ttaaggaacc cttgcatagc
    44881 tatagttata caaaagtagg tggagaggct gattatttgg tctttccacg aaatcgtttt
    44941 gagttggcgc gccttgtgaa atttgccaac caagaaaata tcccttggat ggttcttggc
    45001 aatgcaagca atatcatcgt tcgtgatggt gggattcgtg gatttgtcat cttgtgtgac
    45061 aagctcaata acgtttctgt tgatggctat accattgaag cagaagctgg ggctaacttg
    45121 attgaaacaa ctcgcattgc cctccgtcat agtttgactg gctttgagtt tgcttgtggt
    45181 attccaggaa gcgttggcgg tgctgtcttt atgaatgcgg gtgcctatgg tggcgagatt
    45241 gctcacatct tgcagtcttg taaggtcttg accaaggatg gagaaatcga aaccctgtct
    45301 gctaaagact tggcttttgg ttaccgccat tcagctattc aggagtctgg tgcagttgtc
    45361 ttgtcagtta aatttgccct agccccagga acccatcagg ttatcaagca ggaaatggac
    45421 cgcttgacgc acctacgtga actcaagcaa cctttggaat acccatcttg tggctcggtc
    45481 tttaagcgtc cagtcgggca ttttgcaggt cagttaattt cagaagctgg cttgaaaggc
    45541 tatcgtatcg gtggcgtaga agtgtcagaa aagcatgcag gatttatgat caatgtcgca
    45601 gatggaacgg ccaaagacta cgaggacttg atccaatcgg ttatcgaaaa agtcaaggaa
    45661 cactcaggta ttacgcttga aagagaagtc cggatcttgg gtgaaagcaa gtaggaagct
    45721 gtatttgaaa agctgctgct atgtcatgga aagggggtga aagcctatcg gtagcgaaga
    45781 tgtatgcagg tggttttact ccctgcaaga ggtagtgggg acctgacaga gccccgatcg
    45841 gttaatctat gaaaaagaag gaatttatgc caattgaaaa aaccaattat cgaattcaaa
    45901 aacgtctcta aagtttttga agacagcaac accaaggttc tcaaagacat caactttgag
    45961 ttggaagaag ggaaattcta cacccttcta ggtgcatctg gttcggggaa atcaactatc
    46021 ctaaacatta ttgcaggttt actggatgcg acgacaggag atatcatgct agacggtgtt
    46081 cgtatcaatg atattccaac caacaagcgc gacgtacata ccgtcttcca atcctatgcc
    46141 ttgttcccac atatgaatgt gtttgaaaat gttgcctttc cacttcgctt gcgtaaaatt
    46201 gataagaaag aaatcgagca gcgtgtagcg gaagttctca agatggttca gttggaaggt
    46261 tatgaaaaac gttccatccg caaactttct ggaggacaac gtcagcgtgt tgccatcgcc
    46321 cgtgctatca tcaaccaacc ccgtgtggtc ttgttggacg agcctttatc agcgctggac
    46381 ttgaaattga gaacagacat gcagtacgaa ttgcgtgaat tacaacaacg attgggcatt
    46441 acctttgtct ttgtcactca cgatcaggaa gaagctcttg ccatgagtga ctggattttc
    46501 gttatgaatg atggcgagat tgtccagtct ggaacccctg tggacatcta cgatgagcca
    46561 atcaaccact ttgttgccac ctttatcggg gagtcaaaca tcttgccagg taccatgatt
    46621 gaggactact tggtcgaatt taacggcaaa cgctttgaag cggttgatgg tgggatgaag
    46681 ccaaatgaac ctgttgaggt cgttattcgt ccagaggact tgcgcattac ccttcctgaa
    46741 gaaggcaagc tccaagttaa ggtcgatacc cagcttttcc gtggagttca ttatgaaatt
    46801 atcgcctatg acgaacttgg aaatgaatgg atgatccact caacccgtaa ggctatcgtg
    46861 ggtgaggaaa tcggtctgga ctttgaacca gaagacatcc acatcatgcg tctcaatgaa
    46921 accgaagaag agttcgatgc tcgtattgag gagtacgtag aaatcgaaga gcaagaagca
    46981 ggtttgatca atgcaatcga ggaggaaaga gatgaagaaa acaagctcta aactctttgt
    47041 agtaccctac atgctttgga ttgcgctctt tgtattggca cccttggtct tgattttcgg
    47101 tcaatccttt ttcaacatcg aaggccagtt tagtttagaa aattataaat cttactttgc
    47161 gtcacaaaac ttgacctacc tcaaaatgag tttcaactca gtgctttatg cagggattgt
    47221 gacctttgtg accttgctta tcagctatcc aacagccctc tttttgaccc gtctcaagca
    47281 ccgtcaactc tggctcatgc tgattatcct tcctacctgg atcaatttgc tccttaaagc
    47341 ctatgctttt atcgggattt ttggtcaaaa tggctctatt aaccaattct tggaatttat
    47401 cggaattggt tcacaacagt tgctttttac cgatttttcc tttatctttg tcgcaagcta
    47461 catcgagctc ccctttatga ttttgccgat tttcaatgtc ttagacgaca tggataataa
    47521 tctcatcaat gctagttatg accttggtgc aactaagtgg gagaccttcc gtcatgtcat
    47581 cttccctcta tctatgaacg gtgtgcgaag tggggttcag tcggtcttta tcccaagttt
    47641 gagtctcttc atgctgaccc gtttgattgg tgggaaccgc gttatcacct tggggacggc
    47701 tattgagcag aattttctaa ccaatgacaa ctatggtatg ggttcaacca tcggtgtgat
    47761 tctcatcctg accatgttca tcaccatgtg ggtgactaag gaaaggagag aacgatgaaa
    47821 aaatttgcca acctttatct gggactggtc tttctggtcc tctacctgcc tatcttttac
    47881 ttgattggct atgcctttaa tgctggtgat gatatgaata gctttacagg ttttagctgg
    47941 actcactttg aaaccatgtt tggagatggg agactcatgc tgattttggc tcagacattt
    48001 ttcttggcct tcctatcagc cttgatagcg accattatcg ggacttttgg tgccatttac
    48061 atctaccagt ctcgtaagaa ataccaagaa gcctttctat cactcaataa tatcctcatg
    48121 gttgcgcctg acgttatgat tggtgctagc ttcttgattc tctttaccca actcaagttt
    48181 tcacttggct ttttgaccgt tctatctggt cacgtggcct tctccattcc tatcgtggtc
    48241 ttgatggtct tgcctcgact caaggaaatg aatggcgaca tgattcatgc ggcctatgac
    48301 ttgggagcta gtcaatttca gatgttcaag gaaatcatgc ttccttacct gactccgtct
    48361 atcattactg gttatttcat ggccttcacc tattcgttag atgactttgc cgtgaccttc
    48421 tttgtaacag gaaatggctt ttcaacccta tcagtcgaga tttactctcg tgctcgcaag
    48481 gggatttcct tagaaatcaa tgccctgtct gctctagtct ttctctttag tattatccta
    48541 gttgtaggtt attactttat ctctcgtgag aaggaggagc aagcatgaaa aaaatctatt
    48601 catttttagc aggaattgca gcgattatcc ttgtcttgtg gggaattgcg actcatttag
    48661 atagtaaaat caatagtcga gatagtcaaa aattggttat ctataactgg ggagactata
    48721 tcgatcctga actcttgact cagtttacag aagaaacagg aattcaagtt cagtacgaga
    48781 cttttgactc caacgaagcc atgtacacta agataaagca gggtggaacg acctacgata
    48841 ttgccattcc aagtgaatac atgattaaca agatgaagga cgaagacctc ttggttccgc
    48901 ttgattattc aaaaattgaa ggaatcgaaa atatcggacc agagtttctc aaccagtcct
    48961 ttgacccagg taataaattc tccatccctt acttctgggg aaccttagga attgtctaca
    49021 acgaaaccat ggtagatgaa gtgcctgagc attgggatga cctttggaag ccggagtata
    49081 agaattctat catgctcttt gatggggcgc gtgaggtgct gggactagga ctcaattccc
    49141 tcggctacag cctcaactcc aaggatctgc agcagttgga agagacagtg gataagctct
    49201 acaaactgac tccaaatatc aaggctatcg ttgcggacga gatgaagggc tatatgattc
    49261 agaataatgt tgcaatcggc gtgaccttct ctggtgaagc cagccaaatg ttagaaaaaa
    49321 atgaaaatct acgttatgtg gtaccgacag aggccagcaa tctttggttt gacaatatgg
    49381 tcattcccaa aacagttaaa aaccaaaact cagcttatgc ctttatcaac tttatgttga
    49441 aacctgaaaa tgctctccaa aatgcggagt atgtcggcta ttcaacacca aacctaccag
    49501 cgaaggaatt gctcccagag gaaacaaagg aagataaggc cttctatccc gatgttgaaa
    49561 ccatgaaaca cctagaagtt tatgagaaat ttgaccataa atggacaggg aaatatagcg
    49621 acctcttcct acagtttaaa atgtatcgga agtaggagat aaacgtaaga agacgaatca
    49681 gtcaagctgg ttcgttttta aggaatagaa gtcagttttt agaaccctat ctttttctat
    49741 tctagttgtt tatttgttta tttgcttatt tgcttgccta gtagtatact aagcctatac
    49801 tcttcaaacc acgtcagcgt tgccttgccg tactcaagta cagcttgagg ctagcttcct
    49861 agtttgcttt ttgattttta ttgagtatta accttacaga aagcggcaac aaataatgaa
    49921 aatgtctact tttttcaaaa aaagtttctg gccaaccttt atgattgtta accaaactgc
    49981 tatactattc catttaaagg atggcttgga tcgacaatac ctaacaactg agtccatata
    50041 ttgggtgata ggcaccttta tatttggaaa tattctagta gctgtgttta gtaatatgaa
    50101 aatttgggat aaaaagaaaa atggcagtaa gaaaaaatat atcctgaaaa agtaatcaga
    50161 gatgtaggga attggtctaa ttcaacggag atcatttcca gttgacgcaa gattaaaaaa
    50221 acgatataat aagaaagttg agaattgatt ttcacttgtc ttagtccaga gaaatggcgg
    50281 tgctgcgagc catctaagct aggaagtcat gctactcaat catacaattg cataagaaca
    50341 agagaatgac aagttcattg aatgaaggtg gtaccgcggt ttttcgccct tcgtgatatg
    50401 agcttgtctt ttgatttttg gaggtgttga tgaaaacatt tcttgtcaaa caaaagtttc
    50461 gtcttggagg cgaacgcttc gctatcaaga atgacagggg agaaattgcc tatcaggtgg
    50521 agggatcatt ttttaagatt cctaaaacct ttaccatcta tgatgcggct ggtgaacaag
    50581 tcagtgagat tagtaaagaa atcttgacct tgcttcctcg ttttgagatt cagcttcggg
    50641 atggctcgag ttttgtcatt cgtaagaagt tgaccttctg gcgagataag tatgagtttg
    50701 ataatctagg tcttcgtatc gagggcaata tctgggattt gaatttcaaa ttgctggatg
    50761 atcgcgatca gctgattgcg gaaattaaga aggaactctt ccatctgacc tctacctata
    50821 ccgtaacggt tcttgaggac gcttatgcag acctagtcat ttccctctgt gtcgcgattg
    50881 actatgtgga aatgctggaa agccaatcac attaaacaag taaataagga gacaatatga
    50941 aacaactatc tagtgcacaa gtacgccaaa tgtggcttga tttctgggcg accaaagctc
    51001 actcagtaga accatcagta agtttggttc ctgtaaatga cccaactctt ttgtggatca
    51061 actctggggt agcaaccctt aagaaatact ttgacgggac cattatccct gaaaatccac
    51121 gtattaccaa tgcccaaaag gctatccgta ccaacgacat cgaaaacgta gggaagactg
    51181 cgcgtcacca taccatgttt gaaatgctgg ggaacttctc tatcggggat tacttccgtg
    51241 acgaagctat cacttgggct tatgagcttt tgacaagccc tgaatggttt gatttccctg
    51301 ctgaaaaact ttacatgacc tactatccag acgataaaga ttcttacaac cgctggattg
    51361 aagtgggagt ggatccaagt cacttgattc caattgagga caacttctgg gaaatcggtg
    51421 cgggaccttc tggaccagat acagaaatct tctttgaccg tggggaagcc tttgacccag
    51481 aaaatatcgg tcttcgcctg cttgcagaag atattgaaaa cgaccgttat attgaaatct
    51541 ggaacatcgt tttgtcacaa tttaacgcag accctgctgt tcctcgtagc gaataccagg
    51601 aattgccaca taagaacatt gatacgggcg ctggtttgga gcgtttggtg gctgttatcc
    51661 aaggggctaa gaccaacttt gaaacggacc tcttcatgcc gattatccgt gaagtcgaga
    51721 aattgtctgg taaggtttat gaccaagatg gcgacaacat gagcttcaag gttatcgcag
    51781 accacattcg ttctctttca tttgctatcg gtgatggtgc ccttccagga aatgaaggtc
    51841 gtggttatgt tcttcgtcgt cttctccgtc gtgcttctat gcatggtcaa aaattgggta
    51901 tcaacgagcc tttcctttac aaacttgttc caactgttgg aaaaatcatg gaaagctact
    51961 acccagaagt gcttgagaaa cgtgacttta ttgagaaaat cgttaagagc gaagaagaat
    52021 catttgcccg tacccttcac tcgggtcaac actttgccca aggcattgta gcagacttga
    52081 aagaaaaagg tcaatctgtt atcgctggtc aagatgtctt taaactctat gatacatacg
    52141 gattcccagt tgaattgact gaagaaattg ctgaagaagc tggtatgact gtagaccgtg
    52201 aaggttttga agcagccatg aaagaacagc aagaacgcgc gcgtgcgtca gctgtcaagg
    52261 gtggctcaat gggtatgcaa aatgaaactc ttcaaaacat cactgtagaa agtgtcttca
    52321 actacaatac tagccaattg tcttctaaat tggtagctat cgttgctgac aatgcagaag
    52381 taggagctgt ttcagaagga actgcctctc ttatctttgc ggaaacgtca ttttatgctg
    52441 aaatgggtgg acaggtagct gactacggac aaatcttgga tgagtcaggt aagattgtgg
    52501 ctactgtgac caatgttcag aaagccccaa atggtcaagc ccttcataca gttgaagtcc
    52561 ttgcaccgct tgccttgaac caagaatata ccttggcaat tgatagcaat cgccgtcacc
    52621 gtgtcatgaa aaaccacact gcgactcatt tgcttcacgc tgcccttcac aatatccttg
    52681 gaaaccacgc aacacaggca ggatctctta acgaagttga attccttcgc tttgacttta
    52741 cccacttcca agcagtaact gctgaggaac ttcgtgcgat tgaacagcaa gttaacgaga
    52801 aaatttggga agcacttgaa gtgaagacag ttgaaacgga tattgacact gctaaagaaa
    52861 tgggagctat ggccctcttt ggtgagaaat acggcaagga agttcgtgtc gtgactatcg
    52921 gtgactactc tattgaactt tgtggtggta ctcatgttgg caacacttct gagattggtc
    52981 tcttcaaaat tgtcaaagaa gaaggaatcg gttcaggaac tcgccgtatc ttggcagtga
    53041 ctggtaagga agcctttgaa gcctatcgtg aacaagagga tgctcttaaa gctgtcgcag
    53101 caaccttgaa agcacctcaa gtcaaggaag tacctcacaa ggtagaagga cttcaagaac
    53161 aacttcgtca acttcaaaaa gaaaatgctg agttgaaaga aaaagccgca gctgcagccg
    53221 caggcgatat cttcaaagat gctaaggaag tcaacggtcg tcgttacatt gctagtcaag
    53281 tgtctgtatc cgatgccggt gcccttcgta cttttgcaga taactggaaa caaaaagact
    53341 actctgatct tcttgtccta gttgccgcta tcggtgacaa agtcaatgtc cttgtagcaa
    53401 gcaagacaaa agaccttcat gcaggaaacc ttgtcaaaga attagcacca atcatcgatg
    53461 gacgtggtgg tggtaaacca gacatggcca tggcaggagg aagcaaccaa gctaagatcc
    53521 aagaattgtt ggatgcagta gcaggtaaat tgtaatcaag taaagatcta tccatttggg
    53581 taggtctttt tgtgaataca aaaaagccaa atccgcttgg acctagcttg gttattatga
    53641 gctattagat ggtattgact gcccagacac ttacggatct agctgagaca gggaattgtc
    53701 cataaccttc ctcatcaatt gtaacttgac cttggtggtt accaagtaaa tctacaaagg
    53761 tttgattagt ccattcttga ccgacaaaca ttgacttgct gttttcttgg tcatttgaga
    53821 taaggactgc gattggggat tgattttcag cacctgaacg tacccaaccg atacagttag
    53881 catggtcaaa gtagtcattt tgttctccat aggccaagtc ttttcggatg gctaggaggc
    53941 ggtcaaggat ttctttgaaa tcttcttgag catactggcc tgaaatccca tagtagtctc
    54001 cgtaaaagac acatggaagg ccgtcttggc gtaacaaaat gagggcatag gctgctggct
    54061 tgaaccattc ttcaacggta gactcaaggg cttgtcctcg ttgggtatcg tggttgtcga
    54121 caaaagtcac agccttgtca ggcttgagtt caaccaggct atctgtgaaa atgccacgaa
    54181 ggtcatagtt tgcgccagct tgactggctt caaagagatt ctggtggaga cgaacatcga
    54241 caaggtcaaa gtgttcttcc gttttttcga gatagtccag attggcttcc ttgtctgggt
    54301 tccaaaattc accaaaaaca tagaaatcgt caccgtattt ttccttcata tcgcggatga
    54361 agttgcgcat aaagaaagag tcaatatgct taacggcatc caaacggaaa ccagctacac
    54421 cagtcgtttc catgaaccaa tcagcccagt catagatgtt ttggatgact tcaggatgtt
    54481 taaagtctag gtcggcatac atgaggtagt cgtagtttcc gttttcgtta tcgaccaatt
    54541 cctcgttggc ccagcccttg ttgtcccctt ggatcagata aatcccagat ttactgcgtt
    54601 tggcatcgta gtctgtaccg gtgaagtggt accaatgcca gtggaagcca ttataggtat
    54661 cttggcgacc atcgaaggta aaactagtcc agccattgat ggtgaagggt tctccaagtt
    54721 caactgtacg gtctacagga tcaacttcga taacctgaaa ggcttccctg tgatcggcag
    54781 cagccttgtg gttgagaact acatcggcca taggttgaat tccctgtgct ttaagggctt
    54841 gaatggcttg aagatagtct tctttgaaac catacttggt gcggacagtc cctttttggt
    54901 tgaactctcc taagtcaaat aagtcataga ccccatagcc gacatctttt tcgttggttg
    54961 ccttgaaggc tggtggcatc cagacgtgac tgatccccag atgagctagg tgtggagcat
    55021 tttcagccag acgcgtccag tgttgaccgt cgtggggcag ataccattca aagtattgca
    55081 tgagtgtttg attttgcata atgtttcctc ttacttgtca atcttgttct ttattctatc
    55141 ataaagtatc tattagcgca aacgtttgcg taagatagaa ggaaactatt ttaactactt
    55201 aaaataaagt attgattttt ttgtatcaaa gtgctagtat agcgatatat aatacagata
    55261 aagataggag ttgtcccatg attgaatttc aaaatgttag taagttgtat ggtgataaag
    55321 aggccttgag taatctcaat ttgcagattg aaaatggaga tattatgggc ttgattggtc
    55381 ataatggggc tggaaaatcg accactataa aatccctagt cagtatcatt tcacccagca
    55441 gtggtcgtat tttggtagac ggtcaggagt tatcggaaaa tcgcttggct attaaacgaa
    55501 agattggcta cgtagcagac tcgcctgact tatttttacg cttaacggcc aatgaatttt
    55561 gggaattgat cgcctcatcc tatgatctga gtagatctga cttggaggct agtctagcta
    55621 ggctattgaa cgtttttgat tttgctgaaa atcgctatca ggttattgaa actctttctc
    55681 acggaatgcg tcagaaagtc tttgtcatcg gagcactctt gtctgatccc gatatttggg
    55741 tcttggatga acccttgact ggtttggatc cccaggctgc ctttgatttg aaacagatga
    55801 tgaaggaaca tgcacaaaaa gggaagacag tcttgttttc aactcatgtc ctagaggtgg
    55861 cagagcaagt ctgtgatcgg attgccattt tgaaaaaggg gcatttgatt tattgtggta
    55921 gtgtagagga cttgagaaaa gattacccag accagtcttt ggaaagtatc taccttagtc
    55981 ttgctggtag aaaagaggag gttgcggatg cgtctcaagg tcattaaaaa attagttgat
    56041 atcaatatcc tttattcatc tcaagaagct aatctggcta atctacgaaa gaagcaggct
    56101 aagaatcctg ggaaaaaagt aaatgtttcc gctagagtct taagttctta cattttttcc
    56161 agtctcttga tgatcatctg ttttagtaat atagccattc attttccttt tgaggaaata
    56221 cctatttatt ttagctcgat gattgctatt ttactagtga ttgccttttc aacttcttta
    56281 acggcctttt acaatgtctt ttatgagagt aaggatttgg tatcgtatag gccctatgcc
    56341 tttaaagaat cagagattat aattgctaaa ggactgtctg tccttttgcc agctctaact
    56401 ggaattgtac caatcctagc ttattttctg gtcctctaca ttaggctagc tccttctcta
    56461 tggctgggtt tgcctttgat gctactgtcc ttgaccttat tatttgtctc tgtggctcta
    56521 gtgatggtag tggcagtgca tttcttggct caaactaggg tcttcagaaa gtatcagtct
    56581 attttttcga atgtgatgat tgggatagga gttctcatac ctttaatatt tatcttcttt
    56641 cttcagtcga cttttggaag tattgttgac aaagttagag acattccatt tctcctttat
    56701 cctcttcata tcttttacaa aatagcagtg gagccttttt cgacagaagc cttagtgggt
    56761 ctgctcgctt ggataggact aactctcttc ctgctttatc tgaccaaaaa gaaggtcctt
    56821 cctcgttttt atgacgtgat cctgcttaat agtgaggaga aggtcaaaaa agaacgtcgc
    56881 agcaaggaga gaatttcaac cactaaaaag ggattttttc gcatggtttt acgctaccac
    56941 ctcaccctct tgggacaggg gactggcgtg attacagtgc tttttacaag tgctttcctt
    57001 ccttatctca tgatgatcgg tctgatttcc aaaatccgag attctcagat agttccagac
    57061 attcatcctc catactggtt acccttgttt tttatagctc tctttatagc agttgtcaat
    57121 aacaatatca ccagcctgca ttcaattgcc ttgtccttgg agagggaaaa tgttgatttt
    57181 cttaagagtt taccctttga ctttgctcgt tatgtgaaag tgaaattttg gattatatat
    57241 gctgtccagt cctttttacc agttctgact ttgcttggtc tttctctata tctaggcttg
    57301 cccatcattt cgatgattta ccttcttgta gtctggatca ttgccagtgt catcctttct
    57361 tgccaccatt actttaagga cgttaaaaat ctgtcaacca attggagtag cattacggac
    57421 ctggtgaatc gttcaaatgg catagtcgcc atagttttat tgtttattta tagtgcaatc
    57481 ctgatggccc ttgtaattgg gagcatattc ttggttcagt ctctctcccc tatccttgcc
    57541 atcagcttgg gagtaggagc tcttatcgtc ttgcttgctc ttgctatttt tggctatcat
    57601 tattacctgt cacgcatatt ggcagaaata gaaaaaagat gaactggttg gtcgcttgct
    57661 tgataaattc aattcgacaa acgcttttat agtttgttag aatgtagttg taaatgatta
    57721 agattggtaa tcaaaaatat atagggagga atgttttgaa taagaaatat aacatagttc
    57781 tatttttgtt gtttatagtt tatttatttg gatatttttc aatttcaaaa acgttaattc
    57841 ctataatgtg tgtgttccaa gtatttttga tagaacatat atttagagtt cgaaatagaa
    57901 tgatgcagat aggtgaaatt ataattattg ttgcttctat aatattattt attgatagta
    57961 tattgagttt gtaacaaaag gcttctctat aaaatcaaat tttccagata cctactgaag
    58021 ctgatttatt tctttatctt tcttctacta cctttgtcac taaatttgac agacacatat
    58081 tgctgataca acctctctac ctataatctc acagttaacc tgaggctagt ttcatagttt
    58141 gctatttgat tttcgttgat aaaaagaaat gctcctccaa gacggaagag cattttttac
    58201 tgtgattctt acacatttac ttcctagttt tgcaggaagt ctagtatacc attttttaaa
    58261 agaagagtaa aaaagcaagg gtagtttctt ttttgagaat tgtctaaaag tttgatataa
    58321 tggtagttat gaatagaata agagtcagca aaagggttga aaagaagctt gctaaggggc
    58381 tagttttact agaagccagt gatcttgaga atgtcaatct taaggatcag gaagtagagg
    58441 tgcagggtca ggaaggaaac tttcttggga ctgcctacct ttctcagcaa aacaagggct
    58501 tgggctggtt tatcagcaaa gacaaggtgg ccttcaatca agctttcttt gaaacgttgt
    58561 ttagaaaagc caaagaaaag agaaacgcct actatcaaga tgatttgaca actgcctttc
    58621 gtctctttaa tcaagaggga gatggctttg ggggtctgac agtggacctt tatggcgact
    58681 acgccgtctt ttcttggtat aactcttatg tttatcagat tcgtcagact atatcagaag
    58741 cctttagaca ggttttccct gaggttttag gagcttatga gaaaatccgc tttaagggtt
    58801 tggactatga atctgcccat gtttatggtc aagaagcacc tgactttttc aatgttttag
    58861 aaaatggtgt cctgtatcaa gtctttatga atgatggctt gatgacagga attttcctag
    58921 accagcatga ggttcgcggt agtttagttg acggcttggc tatgggtaaa tccttactca
    58981 atatgttttc ctacacagcg gctttttcag tagctgcggc catgggagga gctagccata
    59041 caacttctgt tgatctagcc aaacgttcac gagaattgtc tcaagcgcat tttcaggcaa
    59101 atgggctcag cacagacgag catcgtttta tagtcatgga tgtctttgag tatttcaaat
    59161 atgccaaacg caaagacttg acctacgatg tgattgtcct agatccgcct agctttgctc
    59221 ggaataaaaa acaaactttc tctgtggcca aggattatca caagttgatt tcccagagtc
    59281 ttgagatttt aaatccggga gggattatca ttgccagtac caatgctgcc aatgtttccc
    59341 gtcagaaatt tacagaacaa attgataaag gttttgcagg aagaagttac cagattttaa
    59401 acaaatatgg tcttccagca gattttgcct ataataaaaa agatgaaagt agtaattacc
    59461 tcaaggtgat tagtatgaag gttagtaaat gaaattaatc gtttcagtaa tgccaagaag
    59521 tttagaggag gctcaggctc tggatgccac gaggtacctg gatgccgaca tcattgaatg
    59581 gcgtgccgac tatctgccta aagaagcgat tttgcaggta gctccagcca tttttgaaaa
    59641 attcgcaggc cgtgagttgg ttttcacgct acgaactcgc tccgaaggtg gagaaatcga
    59701 cctttctcca gaagagtata tccatctaat caaggaagtt gcgcaactct atcaaccaga
    59761 ctatattgat tttgagtact atagctacaa ggatgttttt gaggaaatgc tggacttccc
    59821 aaatcttgtt ttgagttacc ataatttcca agaaacacct gagaacatga tggaaatctt
    59881 gtcagagttg acgatcctaa atccaaaact tgttaaggtt gcggtgatgg ctcacacgga
    59941 gcaggatgtc ttagacttga tgaactatac acgaggcttt aaaaccctca atcctgaaca
    60001 ggaatatgtg accatttcta tgggtaaggt gggcaaggtc tctcgtatca ctgcggatgt
    60061 gactggttcg agttggtctt ttgccagtct ggatgaggtt agtgcccctg ggcagatttc
    60121 tctagctagc atgaaaaaaa tcagggagat tttggatgaa gcttgatggc tatacacgtt
    60181 tagctgcagt tgttgccaat cctattaagc attctatttc tcccttcatc cacaatagag
    60241 cctttgaggc gacagctacc aacggtgctt atgtggcttg ggagattgaa gcgagtgact
    60301 tggtagaaac agtggccaat attcgtcgct accagatgtt tggcatcaat ctgtccatgc
    60361 cctataagga gcaggtgatt ccttatttgg ataagctgag cgatgaagcg cgcttgattg
    60421 gtgcggttaa tacggttgtc aatgagaatg gcaatttaat tggatataat acagatggca
    60481 agggattttt taagtgcttg ccttctttta caatttcagg taaaaagatg accctgctgg
    60541 gtgcaggtgg tgcggctaaa tcaatcttgg cacaggctat tttggatggc gtcagtcaga
    60601 tttcggtctt tgttcgttcc gtttctatgg aaaaaacaag accttaccta gacaagttac
    60661 aggagcagac aggttttaaa gtggatttgt gtgctttaga atatgtttct gaactgcaag
    60721 caaggattgc cgagtcggat ttgctagtta atgccaccag tgtgggcatg gatggccaat
    60781 cctctcctgt tcctgaaaac atagtcttac cagaaactct tttagttgca gatatcatat
    60841 accaaccctt tgaaacaccg tttttgaaat gggctagaag tcagggcaat ccagcagtca
    60901 atggtctggg aatgttactc tatcaagctg cagaagcttt tcaactgtgg acaggcaagg
    60961 aaatgccgac agaagagatt tggcagtctt taacagaaaa ataccaataa agaaagggag
    61021 actctcctat gaaaatcaga atcgatattc ctcaccatcc ttatgatatt cagattgaaa
    61081 aaggttgtat ggcccaggct ggtcagtggt tgcgagaact ctggcaaccg caaaaggtag
    61141 tcattgtgac agataaccat gtagcctctc tctatgcaga gaaggtcaag ctcagcctag
    61201 aagatgctgg ttttcaggta gctgtttttg atttcttaga aggtgaagaa agaaagaatt
    61261 taactactgt tcagaaagtc tatgaatttc tagtcaagca aggtctgact cgtagcgatg
    61321 gaatcgttgc tcttggtggt ggcgttgttg gggacctggc tggatttgta gcctctacct
    61381 atatgcgggg tattcacttt gttcagattc cgactagttt gacagctcag gttgattctt
    61441 ctatcggtgg aaagacaggc gttaatacac catttgctaa aaatatggtg gggacctttg
    61501 cccaaccaga tggggttctg attgatccac ttgttcttga aaccctcgga aaaagagagt
    61561 tgattgaagg gatgggtgaa gttatcaagt atggcttgat tgaggatcca gaactgtggg
    61621 ctctcttgac gggactgaat ggttctgttg agagtatttt ggaacatgca gagaccttga
    61681 ttgaacattc ttgtcaggtg aagcgcaaga tggtggttga agatgagttg gacaatggta
    61741 ttcgtcttta cctcaatttt ggccacacta ttggccatgc catcgaagcg actgccggtt
    61801 atggcaaggt catgcatgga gaggctgttg ccatgggaat ggtacagatt tccaaggttg
    61861 ctgaggaaaa aggcctcatg ccagctggca ttacccaatc tatcacagag atgtgtcaga
    61921 aattcggttt gcctgttgac tatgaaaatt gggaagttga caagctttat caggctctta
    61981 ctcatgacaa gaaagcgcgt ggtaacacct tgaaattggt cttggtgcca gagcttggtt
    62041 cagcgaccat tcacccagtt tctctggaag agatgaaaga ctacttggta aaataaggag
    62101 agtgtatgag atatttaact gcaggagaat cacacggccc ccgtctaaca gctattattg
    62161 agggaattcc agctggactt ccattgacag ctgaggatat caatgaggac cttagacgcc
    62221 gtcagggtgg ctacggtcgt ggtggtcgta tgaagattga gaatgaccag gttgtcttta
    62281 cttcgggcgt tcgccacggg aagacgacag gggcgcctat tactatggat gtcatcaata
    62341 aggaccacca gaaatggctg gacatcatgt ctgcggagga cattgaagac cgccttaaaa
    62401 gcaagcggaa aattactcat cctcgcccag gtcatgccga tttggttggg gggattaagt
    62461 accgttttga tgatttgcga aattctttgg agcgttcatc agctcgtgaa accaccatgc
    62521 gggtggcagt tggtgcagta gccaaacgcc tcttggctga gctggatatg gagattgcca
    62581 accatgtcgt ggtctttggt ggcaaggaaa tcgatgttcc tgaaaatctg acagtcgctg
    62641 aaattaagca aagagctgcc cagtctgaag tttctattgt caaccaagaa cgagaacagg
    62701 aaatcaagga ctatattgac caaatcaaac gtgatggtga taccatcggt ggggttgtgg
    62761 agacagtcgt cggaggcgtt ccagttggtc ttggttccta tgtccaatgg gatagaaaat
    62821 tggatgcaag attggctcaa gctgttgtct ctatcaatgc ctttaaaggg gtggaatttg
    62881 gtcttggctt tgaggctggt tatcgtaaag gcagccaagt tatggatgaa attctctggt
    62941 ctaaagaaga cggttatact cgccgtacca ataatctagg tggttttgaa ggtggtatga
    63001 ctaatgggca acccatcgtt gttcgtgggg tcatgaaacc cattcctact ctttataaac
    63061 ctcttatgag tgtggatatc gaaacccacg aaccttacaa ggcaaccgtg gagagaagtg
    63121 atccgactgc tcttccagct gcaggaatgg tcatggaagc agttgtagca acggttctgg
    63181 cgcaagaaat cctcgaaaaa ttctcatcag ataatcttga ggaactaaaa gaagcggtag
    63241 ccaaacaccg agactataca aagaactatt aaggagttcc tatggcaaaa acaatctata
    63301 tcgcaggtct tgggttgatt ggagcctcta tggcacttgg tatcaaacgc gatcatccag
    63361 attatgaaat tttaggttat aatcgtagtc aagcttcgag agatatcgcc ttgaaagaag
    63421 gtatgattga ccgtgcaacg gatgattttg ctagttttgc tcctttggca gatgtcatta
    63481 tcctcagctt gccaatcaaa caaactattg ctttcattaa ggagttggcc aatttggatt
    63541 tgcgagaagg cgttattatt tcagatgctg gttcgaccaa gtcaaccatt gtggatgcgg
    63601 cggagcagta tttggctggc aagtctgttc gctttgtcgg ggcccatccc atggctggta
    63661 gtcacaagac aggggctgct tcggcagatg tcaatctttt tgaaaatgcc tattatatct
    63721 ttacaccttc aagcctgaca agtcaggaca cgcttaagga aatgaaggat ctgctttcag
    63781 gtcttcatgc tcgttttatc gagattgatg ccaaggagca tgatcgtgtc acttctcaga
    63841 ttagccattt tcctcatatt ttggcttcta gtctcatgga gcagactgcg gtctatgctc
    63901 aagagcatga gatggcaagg cgctttgcgg caggtggttt tcgagatatg acccgaattg
    63961 cggaaagcga gccaggaatg tggacctcca ttctcttgtc caatagcgag atcattctgg
    64021 atagaattga ggatttcaag gaacgtttgg aagcgattgg tcaggccatt agtaagggag
    64081 atgaagagca aatttggaac ttttttaacc aagcgcgtga acaacgccag accatggaaa
    64141 tccataagcg tggtggtgtg gatagctctt acgacctcta tgttgacgtt cctgatgaag
    64201 aagatgtcat cctgcggatt ttggaactgc tacgtggaac ttccttggtt aatatccaca
    64261 tcaacgagga aaatcgtgag gatattcacg gaatcctaca aatttcattt aaaaatgctc
    64321 aagacttgga aagagctgag catctcataa cagaaaatac tgactataca gtcgtcatca
    64381 aataaggaga agaacatgtc aaatatttac gatagtgcaa acgaactcag tcgcggtcta
    64441 cgcggattac cagaatacaa ggctgttaaa gcagctaaag atgcgattgc agcagatgct
    64501 gaggcaagca aaatctttac agattatctt gcctttcaag aggaaattca aaaactagca
    64561 cagacaggtc aaatgccaga tgcgtccttc caagctaaga tggaaggctt tggtaaacag
    64621 attcaaggaa atagcctctt gtcagaattc tttaccaagc aacaacaatt ggccatttac
    64681 ctttctgata ttgaaaaaat tgtttttgaa ccagtttcag aattgctgaa ataagaaaag
    64741 aactatccta aagtcaggaa tttttaagga atttctggct ttttatgata aaataggtaa
    64801 aagtattgca agtatgaggt ccagtatgaa actaaaaaca aacattcgcc atttacatgg
    64861 tagtatccgc gtcccaggtg acaagtctat cagccaccgt tccattatct ttggaagttt
    64921 ggctgagggt gagaccaagg tttatgatat tctgcgaggt gaagacgttc tttcgaccat
    64981 gcaggttttt cgtgaccttg gtgttgaaat tgaggataaa gatggggtta ttaccattca
    65041 aggtgtaggc atggctggct taaaagcgcc acaaaatgcc cttaatatgg gaaattctgg
    65101 cacctcgatt cgcctgattt caggtgtcct tgctggtgca gatttcgaag tagagatgtt
    65161 tggagatgat agtctttcca aacgtcctat ggaccgtgtg acccttccac tgaaaaaaat
    65221 gggcgtcagc atttcagggc aaactgaacg agacttgcct ccccttcgct taaaagggac
    65281 gaaaaaccta agacctattc attatgagtt gccaattgcc tctgcccaag tcaagtcagc
    65341 cttgatgttt gcagccttac aagctaaggg ggagtcagtt attatcgaaa aagagtacac
    65401 ccgtaatcat actgaagata tgttgcaaca atttggtggt catttaagtg tggatggtaa
    65461 gaaaatcaca gtccaggggc cacaaaaatt gacaggacag aaggtggtcg taccaggaga
    65521 tatttccagt gcagcctttt ggttagtcgc aggtttgatt gctccaaatt ctcgtctagt
    65581 gctgcagaat gtggggatca acgaaactcg caccggtatt attgatgtca ttcgtgccat
    65641 gggtggaaaa ttggaaataa ctgaaatcga tccagtcgct aaatctgcta ccttgattgt
    65701 tgagtcttct gacttgaaag gaacagagat tggtggcgct ttgattccac gattgattga
    65761 tgaattgccc attattgccc tgcttgcgac ccaagcccaa ggtgtaacag ttatcaagga
    65821 tgctgaggag ctcaaggtca aggaaacaga ccgtattcag gttgtggcag acgccttaaa
    65881 tagtatggga gcagatatta ctcctacggc agatgggatg attatcaaag gaaaatcagc
    65941 tcttcacggt gctagagtca atacgtttgg tgaccaccgt atcggcatga tgacagctat
    66001 cgcagccctc ttggttgcag atggagaggt ggagcttgac cgtgcagaag ctatcaatac
    66061 cagctatcct agtttctttg atgatttgga gagcttgatt catggctaag gtgttattag
    66121 ggtttatggg ggctggaaaa tcgactattg caagaggatt ggaccctaat taccttgata
    66181 tggatgctct gattgagaag cgcctaggta tgtccattgc gaattttttc gctgaaaagg
    66241 gagaagagac ctttcgtcag gtagaatcag aagtcctagc tgatttacta caaacagatc
    66301 aagtcgtgtc aactggagga ggagtggtta tttctcagag aaatcgtgac ttactcaaga
    66361 ctaatacaga taacatctac ctgaaagcag attttgaaac cctctaccta cgtatcgcag
    66421 ctgataagga caatcagcga ccgctttttc taaataatag caaggaagaa ctagtagcta
    66481 tttttcaaga aagacaggct tggtatgagg aagtggctag tcgggttttg gatgtgacca
    66541 agctaagccc agaggaaatt atagaggaac taagatgaaa attgcttatc taggtcccaa
    66601 gggatcattt tcacaccacg ttgtgcagac agcttttcct catgaggaat tgcaggcttt
    66661 tgccaacatt acagatgtca tcaaggctta tgagcaagga ttagtggact attctgtggt
    66721 gccagttgaa aattctattg agggtagtgt tcatgaaacc ttggactatc tttttcatca
    66781 ggctcacatc caagcagtag cagaaatcgt tcagcctatt catcagcagt tgatggtggt
    66841 tccaggccat actaagattg aaaagatttt ttcacatcca caggccttgg ctcaaggaaa
    66901 gaaattcatc gatgaacaat atacagaggc tcaaatcgag gtaacagcta gtacagctta
    66961 tgcagcccgt tttatttccg aacatccaga tcagcccttt gcagcaattg cacctagaag
    67021 ttctgctgaa gaatatggat tggaactgat tgccgaggat attcaggaaa tggaagccaa
    67081 tttcacacgt ttctgggttc taggagctga aaagcctagt attcccttgc aagcacaaac
    67141 tgaaaagatg agtttggcct tgacattacc tgacaacctt ccaggtgcac tttataaggc
    67201 cctgtcgacc tttgcttggc gaggaattga cttgacaaaa attgaaagtc gtccactcaa
    67261 gacagcactg ggtgaatact ttttcattat cgatgtggat tataccgata aggacttggt
    67321 ccactttgcc caaaaagaat tagaagcgat tggaatccag tataaaattc tgggtgccta
    67381 tcctatttat ccaatatcag accatggaaa ggagagaaga tgagtaaaga aaatctctta
    67441 agtcatcatg agcagttgcg ttatgattat ttgctaaaaa atattcacta tctcaatgag
    67501 agagaaaaaa atgagtttgc ctatttgcaa gaaaagctaa ctcttgctag gggaaatagt
    67561 agctctagct tggaacaaga aagagaagag caggttgact taccaagcta tgcgaaccgg
    67621 agtcgctcac aatccaaatc acaagcactc tctttccctc caaaaaagaa aagacggaag
    67681 ctccgtctta aacgaatttt tatggtgatt ttttcacttt tggtctgtgt ggctttggcc
    67741 atggtattca tgtttttgcg tggttaccaa gatgctagcg caaagaaaac tgctgatgcc
    67801 cgggcagctc aagtagaagt ctttaatggt caggacacta gagatggagt taatatttta
    67861 atcatgggta ctgatggtcg aatcggccag aacagtgttg agacacgaac tgactctatt
    67921 atggtattaa atgtcggggg ctcagataag aaaatgaagc tagtcagttt catgcgtgat
    67981 aatttggtct atatagatgg ttatagtcaa gtgattaacg gtagaaaaca gacagataac
    68041 aagttaaacg tagcctacga gttaggagaa caagaggggc aaaaaggggc agaaatggtt
    68101 cgccaagtct tgaaagataa ttttgacttg gacattaagt actacgcctt ggttgatttc
    68161 caggcctttg ccacagcgat tgacacgctt ttccctgatg gggtgacgat tgatgctcaa
    68221 ttttcaacat tgaatggtcg tcccctaaca gaagctacag tcggagatga tttatacgct
    68281 accgagactg agtctccaac ccaaaccatt aaagtcggaa aacagcagat gaatggctcg
    68341 accctgctca attatgctcg tttccgtgat gatgatgagg cggattacgg ccgtacaaaa
    68401 agacagcaac aagttttaac agcaatttta gagcaaatta aagatcccac taaacttttc
    68461 actggttctg aagctcttgg aaaggttttt gctatgacct caaccaacgt accctatact
    68521 ttcctcctaa caaacggttt atctgttttg gatggagcaa aaaatggtat tgaaaaattg
    68581 acgattccag aactgggtga ctgggtagat gcctatgatg tttatggagg cttgggcttg
    68641 ctggttgatc aaaacaaata tcaaaccaag ctcgctcaaa tgggcttgag ataagataat
    68701 actcaatgaa aatcaaagtg caaactagga agctagccgc aggctgctaa aaacacagtt
    68761 ttgaggttgt agataagact gacgaagtca gttacctata cctacggcaa ggtgaagctg
    68821 acgtggtttg aagagatttt cgaagagtat aagacagaaa aatcaaagtt tgatagctat
    68881 ttggatagca gtcaggcttt gattttttac agtctgcaat agattttcac cccttgtttg
    68941 tggtataatg aaacgatacg atagaaagaa taatgaacaa tatgactgat ttaaaagcaa
    69001 ttcaggctcg tagtctggag atggctgaat attttgtggc cttttgtaaa gaacatgatt
    69061 tgctctgtta tctctgtggc ggaggcgcta ttggtgccct tcgaaacaag ggatttattc
    69121 cttgggacga cgacctagac ttttttatgc ctcgtaaaga ttatgagaaa ttagcagaat
    69181 tatggcctcg ttatgcagat gaacgttatt tcttgtcaaa gagtcacaag gattttgttg
    69241 atcgtaatct ttttattacc attcgtgaca agaaaaccac ctgtatcaag ccttatcagc
    69301 aggatttgga tttgccacat ggtctggcct tggatgtttt gcctttggat tattatccga
    69361 aaaatccagc tgagcggaaa aaacaggttc gttgggcctt gatttattca ctcttttgtg
    69421 cgcaaactat tccagaaaag catggtgctc tcatgaaatg gggaagtcgc attttactgg
    69481 gtttgactcc aaaatctctc tgttatcgca tctggaaaaa agctgagaaa gaaatgacta
    69541 agtatgattt ggctgattgt gatggcatta cagaattatg ctcaggtcct ggctacatga
    69601 gaaacaagta cccaatcaca tcttttgaag acaatctttt cttgccattt gaaggaacag
    69661 agatgcctat tccaatcggc tatgatgtct atctcagaac tgcttttggg gattatatga
    69721 cgcctccacc agcagacaag caggtaccgc atcatgatgc tgtcatcgct gatatggata
    69781 agtcttatac agaatacaag ggagaatatg gtggctaaga aaaaaatctt attttttatg
    69841 tggtcttttt ctcttggagg tggtgcagag aagattctat caaccattgt ttcaaatctg
    69901 gatccagaaa agtatgatat tgatattctt gaaatggagc actttgacaa gggatatgaa
    69961 tctgttccaa agcatgtacg cattttaaaa tcccttcaag attatcgcca aaccagatgg
    70021 ttacgagctt ttttgtggag aatgagaatt tattttccaa gactggctcg tcgtttgctt
    70081 gtaaaagatg attatgatgt tgaagtttct tttaccatta tgaatccacc actgttgttc
    70141 tctaaaagaa gagaagtcaa gaagatatct tggattcatg gaagtattga agaacttctt
    70201 aaggatagct ctaaaagaga atcacataga agccagttgg atgctgcgaa tacaattgta
    70261 gggatttcaa aaaagaccag caattctatc aaggaagttt atccagatta tgcttctaaa
    70321 ttacagacaa tctacaatgg atatgatttt cagactattc tagaaaaatc tcaagagaag
    70381 atcgatatcg agattgctcc tcaaagtatc tgtactatcg gacggattga ggaaaataag
    70441 ggttctgacc gtgtagtgga agtgatacga ttattacacc aagagggaaa aaactatcat
    70501 ctctatttta tcggggctgg tgatatggaa gaggaactga aaaaacgagt caaagagtat
    70561 gggattgagg actatgtaca tttccttggt tatcaaaaaa atccttatca gtatctatct
    70621 cagacgaaag ttcttttgtc tatgtctaaa caagaaggtt ttcctggagt gtatgtggag
    70681 gccttgagtc tgggactccc ttttatctct acgaacgttg gaggggctga ggaattatcc
    70741 caagaaggac gatttggaca aatcattgag agcaatcaag aggcagctca ggcgattact
    70801 aattacatga cttctgcctc aaactttgat gtcgatgagg ctagccaatt cattcaacaa
    70861 tttacaatta caaaacaaat cgaacaagta gaaaaactat tagaggagta gcatggaaac
    70921 tgcattaatt agtgtgattg tgccagtcta taatgtggcg cagtacctag aaaaatcgat
    70981 agcttccatt cagaagcaga cctatcaaaa tctggaaatt attcttgttg atgatggtgc
    71041 aacagatgaa agtggtcgct tgtgtgattc aatcgctgaa caagatgaca gggtgtcagt
    71101 gcttcataaa aagaacgaag gattgtcgca agcacgaaat gatgggatga agcaggctca
    71161 cggggattat ctgattttta ttgactcaga tgattatatc catccagaaa tgattcagag
    71221 cttatatgag caattagttc aagaagatgc ggatgtttcg agctgtggtg tcatgaatgt
    71281 ctatgctaat gatgaaagcc cacagtcagc caatcaggat gactattttg tctgtgattc
    71341 tcaaacattt ctaaaggaat acctcatagg tgaaaaaata cctgggacga tttgcaataa
    71401 gctaatcaag agacagattg caactgccct atcctttcct aaggggttga tttacgaaga
    71461 tgcctattac cattttgatt taatcaagtt ggccaagaag tatgtggtta atactaaacc
    71521 ctattattac tatttccata gaggggatag tattacgacc aaaccctatg cagagaagga
    71581 tttagcctat attgatatct accaaaagtt ttataatgaa gttgtgaaaa actatcctga
    71641 cttgaaagag gtcgcttttt tcagattggc ctatgcccac ttctttattc tggataagat
    71701 gttgctagat gatcagtata aacagtttga agcctattct cagattcatc gttttttaaa
    71761 aggccatgcc tttgctattt ctaggaatcc aattttccgt aaggggagaa gaattagtgc
    71821 tttggcccta ttcataaata tttccttata tcgattctta ttactgaaaa atattgaaaa
    71881 atctaaaaaa ttacattaga acgggggtga ccaagtgatt gatgggaaac gattattatt
    71941 tagtttgacc atagtcagtt atgccttgac gctagtaagt ggaattgtgt atctgtttaa
    72001 taataataat gttagcttac tttctacttt attgttcttg ttggttagta gcttaattgc
    72061 ttgttggaat gatatcaagt attacttaat ccattttatt ttctatttaa ccatttttgt
    72121 atttctggta tcaagaccga ccattgatta ttttagggat ggtgctttgg atacctatca
    72181 tccaatagcc tatcgttttg cctttatagt tgtcatgatt tcgattctgg gcttgaccac
    72241 aggaggcatt ctggctcgtt acttcatagc taggaagaaa ataaaagtag caaatatagg
    72301 aaattctcta aaagaggttt atatcaagcg gttacgcttt gtatcactag gagtttttct
    72361 tctaacctat cctttctatt tcattcggtt atttgaacgg ctcttgtatc gtttgcagac
    72421 ttcctactat gcctactatg caaattttga aagtaaactg ccttatttta cctacatttt
    72481 gtctaccttt acggtctatg caatgtgtat gtatctggca accaagccaa agaaattgca
    72541 ggccacagca gtgcttgtct cctttattgc agctaatact attcatttgg caattgggac
    72601 acgaaatccc tttattttaa gtattttatt tgcttttgtt tattacttta tgcgggagca
    72661 aactgaaaaa ggaaaatgga ttgggtttaa agaaaagtta gcgatttttg taggttctcc
    72721 tattctcatg ttagcgatgg gagtactcaa ttatgtacgg gataatgtcc aagtttccca
    72781 tacaggtttc tgggatatct tacttgactt tatctataaa caagggacta gttttggtgt
    72841 tctggctcga ggttttctat ttaacagtag cctcccttac cgagatttcc gtaattttac
    72901 ttttggtcct gttcttgatt attttgcaag ggggagtttg ggagccattt tcggaggaaa
    72961 agcctttgaa catacaacca atagtgtgga actagctatt gatagtaata gttatgccca
    73021 caatctatcc tatcttgtct tgaacaagga atacttgaaa gggcatggta tcggaagtag
    73081 ttatatcatg gagttgtata ccgactatgg tatgattgga gtctttctgc ttagtttctt
    73141 actcggcgta ttatttatag ccatgctgca agtagcctat cgctcaagga caatcctatt
    73201 tgctttatcc ctactcatct tgaataatct attctttatg ccaagaagca gcttttcaga
    73261 aagtttcttc aatttattta caatgcaatt ctggggaatt gttcttgtga ttatatttgt
    73321 agcaaaaatg cttacaaagg aaaactagta tctactaaac aaaggagaaa aaaatcatgt
    73381 ttgaacatta ttcagtagct gatttgtttg caaatcttta taaaaaacga aaagcaaata
    73441 ttttagctct catcgcttta tttgctctca ttgctgtacc atttacaatt aaagcagtta
    73501 ggaataaaaa cactgtcaaa gatacaacaa gttattcaac ttatcttatc tataaaatca
    73561 ctcctccaga agattcggcc aaaacgattt tgaatcatca aattggtggt tatagtgatt
    73621 tttatgggaa attgattgat ggtaatttga atggagctta tcttttcaat gatgtagaac
    73681 ccagtgagtt gaaaaaaatt gccagtgaat tagacacgac ggaaacaacc ttgaaaaatt
    73741 caacgaatga ctattggtgg aaaaaattga ccgtctacta tatgattgac gatgcagggg
    73801 ttggtgtgaa aattttgaca tcaagtaaag atgccaatga cttgttagag aaaaaaattg
    73861 atgggttgat tgagaaattt aaacatgctt atgcaaatgt gaaaattgaa aaactggaaa
    73921 ccatcaactc taaagaattg aacgcaaatg gtgaaacagc gcttggctta aatgtgaaaa
    73981 atctgattct tcgtttagtt gttattggag tggtttgtgt gattttggtt gtgatgggaa
    74041 atgtgttagt ttatctcttt aatccaacaa tcaatagagt aggtgatttt tctcagtatc
    74101 aaattgattt tgtaacagag attacaacaa ttgctaacct agcagatgtt ttgtcataca
    74161 aaaatactgg acaggaattg accatcgtta gctcaaataa agctatccta gataaattga
    74221 aacagagtca agaagcttta aaaggaatgc attttgtaga tttgcaggat gtatcatctc
    74281 ttttggaaag agatacagtc cttcttgttg aagagtacgg agtgactcgt tataagaaat
    74341 ttgagcaaag tcttcaaatt ctcagaaact taaatcgttc tatcctcggt gtagcaacct
    74401 ttaaattata agtattctga tgtataaggt cttcaaaatc ggctcttagc cgattttgaa
    74461 ggctttttct atctgtctgc agaaattttc tcttggagtc tcctatagaa agaccctagg
    74521 gaaaatctat ccgtatagag gagccttctt ttgataaaat cgtaaaaatc tagtataata
    74581 gatagaactg aaagtatgag gttactagca atgaaaatga aacaaattag tgatacaact
    74641 ttaaaaatca cgatgtcttt agaggatttg atggatcgtg gaatggagat tgctgacttt
    74701 ctcgttcctc aagaaaaaac agaagagttc ttttatgcta tcttggatga gctagagatg
    74761 cctgatagct ttctggatac aggcatgttg agcttccgtg tgactccaaa acctgataag
    74821 gtagatgtct ttgtgaccaa gtcaaagatt gaccaaaatc tagattttga agacttatcg
    74881 gatttgccag atatggaaga attggctcaa atgtctccag atgaatttat caaaaccctg
    74941 gaaaaaagca tcgcagacaa aaccaaggat gatatcgaag ccattcaatc tcttgagcaa
    75001 gttgaagcca aggaagaaga gcaagagcag gctgaacaag aagctgagag taagaaagaa
    75061 ccttacatct actacatcct ttcttttgct aagttggctg acttggtagc ttttgccaag
    75121 acagtgactt ttgaaatgga aacttctgaa ctctacaaaa tgaacgagcg ctattatttg
    75181 accattttag tggatattga aaatcatcca agcccatatc cagcttggct gttggcccgt
    75241 atgcgcgagt ttgcagacga tagtgatatc agtcgctcag tcttacaaga gtatggtcaa
    75301 gtcttgatga gtcacgatgc agtgctcaat ctgcaaaaaa tcggctaatc ctttctggaa
    75361 agctattttc agattttaag aagagcgaat cgtctgattc gttttttctt tttatactga
    75421 aatagtgatt tactataata ggaattttca caaaattctg ttataatggc tatattagaa
    75481 aatttcgagg agataaagat gacagttaaa attgctttac taggatttgg taccgttgca
    75541 agtggtgtgc ctttcctcct aaaggaaaat ggaggaaaaa tcaatcaatc agcacattca
    75601 gatatcaaag ttgctaaggt attggtcaag gatgaagatg aaaaaaatcg cttgcttgca
    75661 gcagggaatg actttaactt tgtaaccaat gtggatgata ttttatcaga ccaggatatt
    75721 actatcgtag tggaattgat ggggcgtatt gagcctgcta aaacctttat cactcgtgcc
    75781 ttggaagctg gaaaacacgt tgttactgct aacaaggacc ttttagctgt ccatggcgca
    75841 gaattgctag aaatcgctca agctaacaag gtagcacttt actacgaagc agcagttgct
    75901 ggtgggattc caattcttcg tactttagca aattccttgg cttctgataa aattacgcgc
    75961 gtgcttggag tagtcaacgg aacttccaac ttcatggtga ccaagatggt ggaagaaggc
    76021 tggtcttacg atgatgctct tgcggaagca caacgtctag gatttgcaga aagcgatccg
    76081 acgaatgacg tagatgggat tgatgcagcc tacaagatgg ttattttgag ccaatttgcc
    76141 tttggcatga agattgcctt tgatgatgta gcccacaagg gaatccgcaa tatcacacca
    76201 gaagacgtag ctgtagctca agagcttggt tacgtagtga aattggttgg ttctattgag
    76261 gaaacttctt caggtattgc tgcagaagtg actccaacct tcctacctaa agcgcaccca
    76321 cttgctagtg tgaatggcgt aatgaacgct gtctttgtag aatctatcgg tattggtgag
    76381 tctatgtact acggaccagg tgcgggtcaa aaaccaactg caacaagtgt tgtagctgat
    76441 attgtccgta tcgttcgtcg tttgaatgat ggtaccattg gcaaagactt caacgaatat
    76501 agccgtgact tggtcttggc aaatcctgaa gatgtcaaag caaactacta tttctcaatc
    76561 ttggctccag actcaaaagg tcaggtcttg aagttggctg aaatcttcaa tgctcaagat
    76621 atttccttta agcaaatcct tcaagatggc aaagagggtg acaaggcgcg tgtcgttatc
    76681 atcacacaca agattaataa agcccagctt gaaaatgtct cagctgaatt gaagaaggtt
    76741 tcagaattcg acctcttgaa taccttcaag gtgctaggag aataagatga agattattgt
    76801 acctgcaacc agtgccaata tcgggccagg ttttgactcg gtcggtgtag ctgtaaccaa
    76861 gtatcttcaa attgaggtct gcgaagaacg agatgagtgg ctgattgaac accagattgg
    76921 caaatggatt ccacatgatg agcgtaatct cttgctcaaa atcgctttgc aaattgtacc
    76981 agacttgcaa ccaagacgct tgaaaatgac cagtgatgtc cctttggcgc gcggtttggg
    77041 ttcttccagc tcggttatcg ttgctgggat tgaactagcc aaccaactgg gtcaactcaa
    77101 cttatcagac catgaaaaat tgcagttagc gaccaagatt gaagggcatc ctgacaatgt
    77161 ggctccagcc atttatggta atctcgttat tgcaagttct gttgaagggc aagtctctgc
    77221 tatcgtagca gactttccag agtgtgattt tctagcttac attccaaact atgaattacg
    77281 tactcgcgac agccgtagtg tcttgcctaa aaaattgtct tataaggaag ctgttgctgc
    77341 aagttctatc gccaatgtag cggttgctgc cttgttggca ggagacatgg tgaccgctgg
    77401 gcaagcaatc gagggagacc tcttccatga gcgctatcgt caggacttgg taagagaatt
    77461 tgcgatgatt aagcaagtaa ccaaagaaaa tggggcctat gcaacctacc tttctggtgc
    77521 tgggccaaca gttatggttc tggcttctca tgacaagatg ccaacaatta aggcagaatt
    77581 ggaaaagcaa cctttcaaag gaaaactgca tgacttgaga gttgataccc aaggtgtccg
    77641 tgtagaagca aaataaagaa tagaagatag gatggggaaa ctcttgacca gagggtttca
    77701 tatccttttt gtgaaaagaa gtttatactc aatgaaaatc aaagagcaaa ctaggaagct
    77761 agccgcaggc tgctcaaaac agtgttttga ggttgtggat agaactgaag aagtcagctc
    77821 aagacactgt tttgaggttg cagatagaac tgacgaagtc agtaacatat atacggtaag
    77881 gtgacgctga cgtggtttga agagattttc gaagagtatt agttaaaaac gtgataaagg
    77941 agaaataaag atggcagaaa tttatctagc aggtggttgt ttttggggcc tagaggaata
    78001 tttttcacgc atttctggag tgctagaaac cagtgttggc tacgctaatg gtcaagtcga
    78061 aacgaccaat taccagttga tcaaggaaac agaccatgca gaaacggtcc aagtgattta
    78121 cgatgagaag gaagtgtcac tcagagagat tttactttat tatttccgag ttatcgatcc
    78181 tctatctatc aatcaacaag ggaatgaccg tggtcgccaa tatcgaactg ggatttatta
    78241 tcaggatgaa gcagatttgc cagctatcta cacagtggta caggagcagg aacgcatgct
    78301 gggtcgaaag attgcagtag aagtggagca attacgccac tacattctgg ctgaagacta
    78361 ccaccaagac tatctcagga agaatccttc aggttactgt catatcgatg tgaccgatgc
    78421 tgataagcca ttgattgatg cagcaaacta tgaaaagcct agtcaagagg tgttgaaggc
    78481 cagtctatct gaagagtctt atcgtgtcac acaagaagct gctacagagg ctccatttac
    78541 caatgcctat gaccaaacct ttgaagaggg gatttatgta gatattacga caggtgagcc
    78601 actctttttt gccaaggata agtttgcttc aggttgtggt tggccaagtt ttagccgtcc
    78661 gatttccaaa gagttgattc attattacaa ggatctgagc catggaatgg agcgaattga
    78721 agttcgttct cgttcaggca gtgctcactt gggtcatgtt ttcacagatg gaccgcggga
    78781 gttaggcggc ctccgttact gtatcaattc tgcttcttta cgctttgtgg ccaaggatga
    78841 gatggaaaaa gcaggatatg gctatctatt gccttactta aacaaataaa acagagaggg
    78901 tggggtttcc cactttcttc atttctagaa tatgaataga agggatttat gaaacaccta
    78961 ttatcttact tcaaacccta catcaaggaa tcaattttag cccccttgtt caagctgtta
    79021 gaagctgttt ttgagctctt ggttcccatg gtgattgctg ggattgttga ccaatcttta
    79081 cctcagggag atcaaggtca tctctggatg cagattggcc tgctccttat ctttgcagta
    79141 attggcgttt tagtggcctt gatagctcaa ttttactcag caaaggcagc agtaggtttt
    79201 gctaaggaat tgacaaacga tctttatcgt catattcttt ccttgcccaa ggacagcaga
    79261 gaccgtctga caacttctag tttggtcact cgcttgactt cggataccta ccagattcag
    79321 actggtatca atcaattcct gcgtctcttt ttacgagcgc ccattatcgt ctttggtgcc
    79381 atttttatgg cttatcgaat ctcagctgag ttgactttct ggttcttagt catggttgcc
    79441 attttgacca ttgtcattgt agggttatct cgattggtca atcctctcta cagtagtctc
    79501 agaaagaaaa cggaccaact ggttcaggaa acgcgccagc aattgcaagg gatgcgggtt
    79561 attcgtgctt ttggtcaaga aaaacgagag ttacagattt ttcaaaccct taaccaagtt
    79621 tatgctagat tacaagaaaa gacaggtttc tggtctagtt tattaacacc tctgacctat
    79681 ctgattgtca atggaactct tctcgttatt atctggcaag gctatatttc aattcaagga
    79741 ggagtgctca gtcaaggtgc tctcattgct cttatcaatt acctcttaca gattttggtg
    79801 gaattggtca agctagccat gttgatcaat tccctcaacc agtcctatat ctcagccaag
    79861 cgaatcgagg aagtctttgt tgaggctcca gaggatatcc attcagagtt agaacaaaag
    79921 caagctacca gagataaggt tttacaagtc caagaattga cctttaccta tcctgatgca
    79981 gcccagcctt ctctgagaga catttccttt gatatgactc aaggacaaat tctaggtatc
    80041 atcgggggaa ctggttctgg taaatcaagc ttgattcaac tcatacttgg actttatcca
    80101 gtaaacaagg gaagaattga cctttatcta gatggattga gtcctcttaa tttggagcaa
    80161 tggagatctt ggattgccta tgtgccacaa aaggtcgaac tctttaaggg aactattcgt
    80221 tccaacttga ctttaggttt aaatcaagaa gtgactgatc aagaactctg gcaagccttg
    80281 gaaattgctc aagctaagga ttttgtcagt gataaggaag gactcttgga tgctctagtt
    80341 gaagcaggag ggcgaaattt ctcaggtgga caaaaacaaa ggctgtctat cgcacgagca
    80401 gtcttgcgcc aggctccgtt tctcatccta gatgatgcga cctcagcact ggacaccatt
    80461 acagagtcca agctcttgaa agctattaga gaaaattttc caaacatgag cttaattttg
    80521 atctctcaac gaacctcgac tttacagatg gcggaccaga ttctcctctt ggaaaaaggt
    80581 gagttgctag ctgttggcaa gcacgatgac ttgatgaaat ccagtcaagt ctatcgtgaa
    80641 atcaatgcat cccaacatgg aaaggaggac tagaatgaaa cgacaaactg taaaccagac
    80701 gctcaaacgt ttagtcgtag atttagcaaa ccatcccttc ctccttttcc tagcctttct
    80761 aggaactatt gcccaagttg gcttatcaat ttacctacct attctgattg ggcaggtcat
    80821 tgaccaagtc ctagtggctg gttcatcact agttttttgg cagatttttc tccagatgct
    80881 cttggtggta ataggaaata ctctggtaca atgggccaat cctctcctct ataatcgtct
    80941 aatcttctct tataccagag atttacggga gcgaatcatc cataagctcc atcgtttacc
    81001 gattgccttt gtagataggc aaggtagtgg agagatggtt agtcgtgtaa ccacggacat
    81061 cgaacagttg gcagctggct tgaccatgat ttttaaccaa tttttcattg gtgttttgat
    81121 gattttggtt agtattctag ccatgctcca aattcatctc ctcatgactc tcttagtctt
    81181 gctgttgacg ccactgtcca tggtgatttc acgctttatt gccaagagat cctatcatct
    81241 cttccagaag caaacagaga cgaggggaat tcagactcag ttgattgaag aatcgcttag
    81301 ccagcagact ataatccagt ccttcaatgc tcaaacagaa tttatccaaa gattgcgtga
    81361 ggctcatgac aactactcag gctattctca gtcagccatc ttttattctt caacggtcaa
    81421 tccttcgact cgctttgtaa atgcactcat ttatgccctt ttagctggag taggagctta
    81481 tcgtatcatg atgggttcaa ccttgaccgt cggtcgttta gtgacttttt tgaactatgt
    81541 tcagcaatac accaagccct ttaacgatat ttcttcagtg ctagctgagt tgcaaagtgc
    81601 tctggcttgc gtagagcgta tctatggagt cttagatagc cctgaagtgg ctgaaacagg
    81661 taaggaagtc ttgaccagtg accaagttaa gggagctatt tcctttaaac atgtctcttt
    81721 tggctaccat cctgaaaaaa ttttgattaa ggacttgtct atcgatattc cagctggtag
    81781 taaggtagcc atcgttggtc cgacaggtgc tggaaaatca actcttatca atctccttat
    81841 gcgtttttat cccattagct cgggagatat cttgctggat gggcaatcca tttatgatta
    81901 tacacgagca tcattgagac agcagtttgg catggtgctt caagaaacct ggctcacaca
    81961 agggaccatt catgataata ttgcctttgg caatcctgaa gccagtcgag agcaagtaat
    82021 tgctgctgcc aaagcagcta atgcagactt tttcatccaa cagttgccac agggatacga
    82081 taccaagttg gaaaatgctg gagaatctct ctctgtcggc caagctcagc tcttgaccat
    82141 agcccgagtc tttctggcta ttccaaagat tcttatctta gacgaggcaa cttcttccat
    82201 tgatacacgg acagaagtgc tggtacagga tgcctttgta aaactcatga agggccgcac
    82261 aagtttcatc attgctcacc gtttgtcaac cattcaggat gcggatttaa ttcttgtctt
    82321 agtagatggt gatattgttg aatatggtaa ccatcaagaa ctcatggata gaaagggtaa
    82381 gtattaccaa atgcaaaaag ctgcggcttt tagttctgaa taagccattc tcttttgaaa
    82441 gtttatggac gaaaaaagtt gccttcgagt gacttttttg ttacaatagc tagaaaaatt
    82501 gttcactgta atactcaatg aaaatcaaag agcaaactag gaaactagcc gtaggttgct
    82561 caaagcacag ctttgaggtt gcagatagaa ctgacgaagt cagtaaccac acctacggca
    82621 aagtgaatct gaagtggttt gaagagagta caacttgtct tttagaaaag gagcctataa
    82681 tgaaagtctt tcagcatgta aatatcgtga cttgtgatca agatttccat gtttatcttg
    82741 atggaatctt agcagtcaag gattctcaaa tcgtctatgt cggtcaagat aagccagcgt
    82801 ttttagagca agctgagcag attatggact atcagggagc ttggattatg cctggtttgg
    82861 tcaattgtca cacccattct gcaatgacag gtctgagagg gatccgagat gacagcaatc
    82921 tccatgaatg gctcaatgac tatatctggc cagcagaatc tgagtttact cccgacatga
    82981 ctaccaatgc ggtcaaagaa gccctgacag agatgctcca gtcaggaaca acaaccttta
    83041 acgatatgta taatcccaat ggtgtggata tccagcaaat ttatcaggtg gtgaaaactt
    83101 ccaagatgcg ttgttatttt tctccgactc tcttttcttc agagacagaa acaactgctg
    83161 agactataag cagaactcga tccatcatag atgaaatctt aaaatataaa aatccaaatt
    83221 tcaaggttat ggtagcacct cattctccgt atagctgcag tagagacttg ctggaagcga
    83281 gtttggaaat ggcaaaagag ctaaatattc cgctccatgt ccatgtggcg gagaccaagg
    83341 aggaatcagg aattatcctc aaacggtacg gcaaacgccc ccttgctttt cttgaagaac
    83401 tgggttattt agatcatccg tccgtatttg ctcacggggt cgaattaaac gagagagaaa
    83461 ttgaacgctt ggcatcttct caagtggcta tcgcccacaa tcctatcagt aacctcaaac
    83521 tggcatcagg aattgctcca attatccagc tccaaaaagc gggagtagca gtcggaattg
    83581 cgactgactc ggttgcttcc aataacaatc tagatatgtt tgaggaagga aggactgcag
    83641 ctcttcttca gaagatgaaa agtggggatg ccagccagtt tccaatcgaa acagctctca
    83701 aggtactgac aatcgaaggg gctaaggtcc ttggaatgga aaatcagata ggaagtctgg
    83761 aagtcggcaa gcaagcagat tttctggtca ttcaaccaca agggaaaatt catctccaac
    83821 ctcaggaaaa tatgctgtct cacctggttt atgcagttaa atctagtgat gtagatgatg
    83881 tttatatcgc cggagaacag gttgttaagc aaggtcaagt cctgacagta gaactttaaa
    83941 agaaaaatca cgaaaaattt taaaaaaagt ttgcaaaaat cttgcattct ttttttgact
    84001 atgctatact tgtatacggt ttaaaaaaac tgcctaagac agtaggggag ctcgactcat
    84061 aaatatccta ccgaggacaa aacgtatcat gtaaaaagaa gcgtattgta ctttcgtgtc
    84121 taggtttggg cgcgtttttc tttttgaaaa attccccaag caaaataatt acggaggtga
    84181 acacactaat gagtgaagca attattgcta aaaaagcgga actagttgac gtagtagctg
    84241 aaaaaatgaa agctgctgca tctatcgtcg ttgtagacgc tcgtggtttg acagttgagc
    84301 aagatacagt tcttcgtcgt gagcttcgtg gaagcgaagt tgagtataaa gttattaaaa
    84361 actcaatctt gcgtcgtgca gctgaaaaag ctggtcttga agatcttgca tctgtatttg
    84421 ttggaccatc tgcagtagca ttttctaatg aagatgttat cgcaccagcg aaaatcttga
    84481 acgacttttc taaaaacgct gaagcacttg aaattaaagg tggtgcaatc gaaggcgctg
    84541 tcgcatctaa agaagagatt cttgcacttg caactcttcc aaaccgcgaa ggacttcttt
    84601 ctatgctcct ttctgtactt caagcgccag tgcgcaacgt tgctcttgca gtcaaagcgg
    84661 ttgcagaaag caaagaagac gcggcttaat cttaagctac acagcgtagc ctagctacga
    84721 aaaaaactat tataaaattt aaaacttatt tggaggaaat aacaatggca ttgaacattg
    84781 aaaacattat tgctgaaatt aaagaagctt caatccttga attgaacgac cttgtaaaag
    84841 ctatcgaaga agaatttggt gtaactgcag ctgctcctgt agctgttgct gcagctgatg
    84901 cagctgatgc tggtgctgct aaagattcat tcgacgttga attgacatct gcaggcgaca
    84961 aaaaagttgg cgttatcaaa gttgtacgtg aaatcactgg tcttggtctt aaagaagcta
    85021 aagaacttgt tgacggtgca ccagcacttg ttaaagaagg cgttgcaact gcagaagctg
    85081 aagaaatcaa agctaaattg gaagaagctg gagcttcagt tactcttaaa taatagagta
    85141 tcgcaatttg attgcggaat ccctatttac cagtctttga gagcgataag cgattgatag
    85201 aaactgataa atttatttag tttcctacca aaaaccctac caaaaattct ttggcagggt
    85261 ttttcttttt aataaatttt cggaggtaga cactagattg tctacccctt tttttgtgtt
    85321 tcggaggtaa ttatgcaaaa ggaaggacag tcatcacgtc aattcgtgaa gagtcatctc
    85381 atgactatca tgggagttga tattgtaaaa gcaactcagt tagttgatga aatggaacaa
    85441 gtaggtttaa tccgatttga tgaatttgga aatgttggaa ttttagtctt ggagggacaa
    85501 tcatgaagcg tattaccgct agtcaatatc agacatcaga gcgttattat aagctcccca
    85561 aacttttatt tgagagtgaa cggtataaga atatgaaact ggaggttaag gtggtttact
    85621 cagttttaaa agatcggttg gagttgtctt tgagcaaagc ttggattgat gaggatgggg
    85681 ctatttattt gatttattcc aattcaaatt tgatggcact tttaggctgt tcaaagtcaa
    85741 aattactctc catgtgagtt tgaggtgaca tttttagatg attaccataa aaaacataat
    85801 tacccactat tttacgaatc ctatcttcaa aacgttatgg aattccttga aagtcaagac
    85861 ataaagaatg gggttgatgc ctttgtagat gatcatcaaa atctcgtttt tgttttatat
    85921 ggacaaggct atcgagccga gggaaaagag ggaatactta caacccaagt aactgtaaaa
    85981 gcttatgatg aagacaagaa accgattaac ttcgcaaatt tattagattc cttaatcgtc
    86041 tcagaatatc aaatggaacc gaatctttgg gaggtctccc atgattgatc tctatctaag
    86101 taaaaataga caaagaaatc aacttctttt agatttcttc caaaactatg gcatagaggt
    86161 atcttgtcat tcagtttctg aaatgacaaa ggacaaatta attgagatga tgagctattc
    86221 ttcagattgt tttgagtttt tatctcccaa tttattacga tttaagaacc gtgacaatct
    86281 aagattaacg gatttcgttg agataatttt aaaaaatcct gaactaacca tcagacttcc
    86341 tcttgcggtt tcaaataagc gagtttatcc aagtctgaat ttggaagagg ctagagctct
    86401 attgccaaga gatacgaaac aattgattta catggcgcaa acacattatt tatctaacta
    86461 aaggagaagt aatatggctg aacgattttg ggagaacttg tccattattt tggctgaaag
    86521 aaatatcagc tggattgagt taaccagaaa aatgtttgcg ggagagtttc actatccaag
    86581 tgaattgaat cgtttatatc aaaagattcg ccactacaag atggaacaac gaatgcctca
    86641 aagtccatgg gtagaaagga ttgtgcagat attagattta gattatgaag atttatttcg
    86701 gaggtaacta tgaaaagaat aattccagtt tatatattcc aacaagtaaa tgtcctattg
    86761 gtatctctat acttattgaa atttctttgt atcggtgagt taactatact acaggttctc
    86821 tatggtgcgt ctcttttttc ttttttatgg atgtatggtc aacgaaaaca agtggtcaag
    86881 gtcaatatga aaactaggat gaaatgcctt ggtattggac tagctagtct actgattata
    86941 agtctatgtt ttagcctgat tcatgctcaa ggaagcacga atcaaacaaa tttaattggc
    87001 cttcaacatc aagttccttg gttttcattt ttattgttct taatcaatgc gagtatggtt
    87061 gaagaatttc tgtatcgtga aattttatgg aacttggtta gaaaattaga tattcgagtt
    87121 gctttgacaa gtgttttatt tgccttagta catcatccag gaaccattct agcttggtgt
    87181 ctgtacgttt cacttggaat gtttttaggt atggtgcgct ataaatctga cttatgggga
    87241 agtatggggt tacatttggt gtggaacttt ttagtttata gtttgctgct tttttaaaat
    87301 aggtgacctg atttatctca taaatctgta gtttttatgg gattctcttt taatttagaa
    87361 ataaaatata ttacctatat aaaataaaga aactagaaat attttttcaa tttttttaga
    87421 aataaaatat tatatagaaa ttccgaaaag aaataataaa accaaaataa aatattacta
    87481 aaatatttta acatgaacat attattagtg ataaacgttc ttacaataca tataattacg
    87541 ataaaaagaa taaaaactat tatattttta tgtttgttgt tctgttatga aacgaaagaa
    87601 attggaaact agtttctaat ttatgaaaaa tattgaaaaa aaaaaaaaag tgttaaaata
    87661 aagaatgtaa acgtttactt caactaagga gctcatatgt tactgcaaaa agaactaatt
    87721 ccaatgatag aagctaactt accaaatatg gcatatgctg aaaaagacat tgctaaattc
    87781 ttcttaaaac agcaacctct gaatgattat tcatctaaag cattgtgcga ataccttaat
    87841 gtatccaaag caacattgac tcgatttgcg aaaaaatgtg gttttaaagg ttttagacaa
    87901 ttcattttca aataccaaga gatgattcat gagaaagaaa agttggcatt atatacagag
    87961 gcaacagaaa aagttttatc cgactatgag gaaatgttga gaaaaactta cacggttctt
    88021 gatgaagttc aacttgagcg tattgctgag atgatagaaa ctgctgagcg tgtatatctc
    88081 tacggtaaag gaagttctgt tcttgcttta caagaaatga agatgagatt tatgcgtctc
    88141 ggagtgattg gtgaagtatt atcagacgag gatatgattt tgtggagtag cttactactt
    88201 aatgaaaatt gccttgtcat tggagcatcc atttcaggtc aaactgatat tgtactagaa
    88261 ggtctacaaa aagctgcaga taaaggcgct aaaacagttt taatgactac aagaaaattt
    88321 gacgaagaag attgtttctt tgatgaacta ttgttattag cttcgaccga tcatctctcg
    88381 tatggcaatc gcatatcacc tcagtttcca atacttttaa ttacagactg cttattctct
    88441 aattatctgg aaagtccaga gagacaatat tattacaatc aaactattat ccataaggag
    88501 gaataataaa atgagccaaa tttggactaa agaaaaattt ataagccaag ttcaaggtgg
    88561 agtcattgtt tcttgtcaag ctttacctgg tgaagccctt tataatgaag aatttagctt
    88621 gatgcctttt atggctaaag cagctttaga ggcaggagca gtgggcattc gcgcaaattc
    88681 tgtgcgtgat attaaagcaa ttcagaaagt agtagattta ccaataattg gaattatcaa
    88741 aagggattat ccacctcaag aaccatatat tactgctacg atgaaagaag tagatgaact
    88801 tgtagaatgc ggaacaacag tcattgcatt tgatgcaact ttaagaccaa gatatgatgg
    88861 cttagttgtc agtgaattta tcaaaaaaat aaaagaaaaa tatccgaatc aattgctgat
    88921 ggcggatgta agtaatttag atgaaggtct ctatgcattt aaatcaggcg ttgattttgt
    88981 tggtacaaca ttatcaggtt acacaagtac aagtgtacaa tcagatgagc ctgattttga
    89041 actaatgaaa aaattggctg attttaatat tccggtaatt gccgaaggaa aaattcatta
    89101 tccagaacaa ttaaaaaaag cttatagttt aggtgttacc agtgtagtca ttggtggagc
    89161 gattacacgt ccaaaagaaa ttgctcagcg atttattaat gtcatcaaat aaaaaacaat
    89221 ataaaggaga aatctgatga aagatttaac taaatacaaa ggcgttatcc ctgcatttta
    89281 tgcttgctat gatgaaaatg gtgaaattag ccaagatcgt gtaaaatctc tggtacaata
    89341 tttcattgac aaaggtgtaa aaggtatcta tgtaaatggt tcttcaggtg aatgtattta
    89401 ccaaagtgta gaagatcgta aacaaattat tgaagctgtt atggaagttg ctaaaggtaa
    89461 attaacagtt atcaaccata ttgcatgtaa taacacgaaa gatagtatcg aattggcaaa
    89521 acattcagaa agtgttggag tcgatgctat tgcagctatc ccacctattt atttcaaatt
    89581 gccagagtat tcaatcgcag catattggaa tgcaatgagt gaagctgcgt caaatacaga
    89641 ttttattatc tataatattc cacaattggc aggggttgcg ttgactggta gtttgtatgc
    89701 aacaatgcgt caaaatcctc gtgtgattgg agttaaaaat tcttctatgc ctgtacaaga
    89761 tattcaaatg tttgtagctg caggtggaga agattacatt gtattcaatg gtccagatga
    89821 acaatatctt ggtggtcgct tgatgggagc agaagctggt attggtggta cttatggcgt
    89881 tatgccagat ttgttcttga aattggaaag tttgattcaa gaacgagatt tagatacagc
    89941 taaaaaactt caatatgcta tcaatgaagt tatctataag atgatatcag gtaaggcaaa
    90001 tatgtatgct gtagcaaaag aagttttgcg tctaaatgaa aaacttgatt taggttctgt
    90061 tcgtcaacct ttagaagcat tggcagaagg tgacttggaa gttgcaaaac aagcagcaga
    90121 acttattcaa caagcacgaa aagaattttt ataataaata aaatcaatat ggagatatgt
    90181 tatgggcaca acaggattta caataattga cttaattatc ttgattgttt atttacttgc
    90241 ggtgttggtt gcaggtatct atttctctaa aaaagagatg aaaggaaaag agttctttaa
    90301 aggagatggt tcggttcctt ggtatgttac ttcggtatcc atttttgcca caatgctcag
    90361 tccgatttcc ttcttgggac tcgctggtag ctcttatgca ggtagctgga ttttatggtt
    90421 tgctcaatta gggatggtag tagctattcc actgacaatt cgttttatct tacctatctt
    90481 tgcacggata gacatcgata cggcatatga ttacttggat aaacgtttta attctaaagc
    90541 acttcgtatt atttcagcac tcttgtttat tatttatcaa ttgggacgta tgtctatcat
    90601 tatgtacctc ccatcagctg gtttatcagt attgacagga attgacatca atattttgat
    90661 tattttgatg ggtgtagttg caattgttta ttcttatact ggtggtctaa aatccgtatt
    90721 atggacagac tttattcaag gtgtgattct gattagtggt gtcgttttag ctttatttgt
    90781 actgattgct aatattaaag gtggctttgg tgcagtagca gaaacattag caaacgggaa
    90841 attccttgct gcaaatgaaa aacttttcga tcctaacttg ctttcaaact ccatcttttt
    90901 aattgtgatg ggttcaggct ttacaatctt gtcttcctat gcttcatctc aagatttggt
    90961 tcaacgtttt actacaacac aaaatattaa gaaacttaat aagatgttgt tcacaaacgg
    91021 tgttttgtca cttgcaactg caacagtctt ttacttgatt ggtacaggct tgtacgtatt
    91081 ctatcaagta caaaatgcag atagtgcagc tagcaatatc cctcaagacc aaatctttat
    91141 gtactttatt gcataccagt taccagtagg tatcacaggt ttgatcttgg cagcgattta
    91201 tgcagcatct caatcaacta tttcaacagg tttgaactct gttgcaactt catggacatt
    91261 ggatattcaa gatgtcattt ctaaaaatat gtcagacaat cgtcgtacga aaattgcaca
    91321 attcgtatct ctagcagtag gtttattctc aattggtgtt tccattgtca tggctcactc
    91381 agatattaaa tctgcatacg aatggttcaa tagtttcatg ggacttgtac ttggtctact
    91441 tggtggtgta tttattcttg gatttgtttc taaaaaagca aataaacaag gtgcttatgc
    91501 agcgctgatt gtatcaacca tcgtcatggt atttattaaa tacttccttc ctccaacagc
    91561 tgttagctac tgggcatatt cattgatttc aatctctgta tcagtagttt caggttatat
    91621 tgtatctgtt cttactggaa ataaagtatc tgcacctaaa tatacaacga ttcatgatat
    91681 tacagaaatt aaagcggatt caagttggga agttcgtcac taatagaaaa gagaaaataa
    91741 tatgattatt tctgaacaat ctgattttaa acgatatgct tctgtcaata aatatttttc
    91801 aaaagtctgt gattttttag aaaatacaaa tttgacagat ttagttgatg gaaaaattga
    91861 tattgacggg gaaaatgttt ttgcaaattg tatgacttat ctagctgatg gagttccagg
    91921 agatattttt gaaactcata agaaatattt agatattcat attgttgttg aaaatactga
    91981 aaaaatggca gtaacttccc cagttcgtgc ccagtcacgt gtacctttta gcgaagagaa
    92041 ggatattgct ttttacgata gcaaagacta tcaaattgtt gaattgcttc cagggaatat
    92101 gttggtgact tttgaagaag atcttcacca accaaagatt cattgcaatg atgaaactgt
    92161 taaaaaactt gttatcaaag ttttaaacga ggaaaaataa aatgaaaaaa aatattaaac
    92221 aatatgtaac cttaggtact gtagtggtat tatcagcatt tgttgctaac tcagttgcag
    92281 ctcaggagac tgaaacttct gaagtatcaa caccaaagtt ggtgcaacct gttgcaccaa
    92341 cgactccgat ttcggaagta caacctacat cggataactc ttcggaagtt actgtacaac
    92401 ctcgaacagt tgaaactact gttaaggatc catcttctac agcggaagaa actcctgtct
    92461 tagaaaaaaa taatgttact ttaacagggg gcggagaaaa tgttactaaa gagttaaagg
    92521 ataaatttac tagcggtgac tttactgtag tgattaagta caatcagtca agtgagaaag
    92581 gcttacaagc tctgtttgga atatctaatt ccaaacccgg tcaacaaaat agttatgtag
    92641 atgtgttcct tagagacaat ggtgagttgg ggatggaagc gcgtgatact tcttccaata
    92701 aaaataacct agtatccaga cctgcttcag tttggggtaa gtacaaacaa gaggctgtga
    92761 ctaacactgt tgcagtagta gcagattcag tcaaaaaaac atattcttta tacgcaaatg
    92821 gtacaaaagt agtagaaaag aaagtggata atttcctaaa catcaaggat attaaaggta
    92881 ttgattacta tatgcttggg ggagtgaaac gtgcaggaaa aacggcgttt ggttttaacg
    92941 gaacactaga aaatatcaaa ttctttaata gtgcattgga tgaagaaact gttaaaaaga
    93001 tgacaacaaa cgctgttact ggacatttaa tttatacggc taatgataca acaggttcta
    93061 actatttccg tattccagtt ctgtatactt ttagcaatgg tcgggtattt tcaagcattg
    93121 acgctcgtta cggtggaact catgatttct tgaataaaat taatattgct acaagttata
    93181 gtgatgataa tggtaagaca tggactaaac caaaattaac attggcattc gatgattttg
    93241 cgccagtacc attagaatgg cctcgtgaag ttggtggacg tgacttacaa atcagcggtg
    93301 gtgcaaccta tattgactct gttattgttg aaaaaaagaa caaacaagta ctcatgtttg
    93361 ctgatgtgat gcctgctgga gtaagtttta gagaagcaac tagaaaagat tcaggttata
    93421 aacaaattga tggtaattat taccttaaat taaggaaaca aggtgatact gattacaatt
    93481 atactattcg tgagaatggt actgtatacg acgatcgtac caacagacca actgaatttt
    93541 cagtagataa aaatttcggt attaaacaaa atggtaatta tttgacggta gagcaatatt
    93601 cggtttcatt tgaaaataat aaaaagactg aatatcgtaa tgggactaaa gtccatatga
    93661 atatcttcta caaagatgca ttgtttaaag tagtgccaac gaactatatt gcatatattt
    93721 ctagcaatga tcatggcgaa tcttggtctg caccaacttt attacctcct ataatgggac
    93781 ttaatcggaa tgcgccatat ttaggtcctg gacgtggaat cattgaaagc tcaactggac
    93841 gtattcttat tccgtcttac actggtaaag agtctgcgtt catttatagt gacgataatg
    93901 gagcatcttg gaaagttaaa gtagtgccac ttccttctag ttggtcagca gaagcacaat
    93961 ttgtagaatt gagtccagga gtaattcaag catatatgcg tacaaataat ggtaaaattg
    94021 catatttaac aagtaaagac gcaggtacta cttggagtgc accggaatat ttgaaatttg
    94081 tttcaaatcc aagttatgga acacaattat caatcatcaa ttatagccaa ttgattgatg
    94141 gtaaaaaggc tgtcatttta agtactccaa actccacaaa tggtcgtaaa cacggacaaa
    94201 tttggattgg tctaattaat gatgataata caattgattg gcgttatcat cacgacgttg
    94261 attatagtaa ctatggatac tcatattcaa cattgacaga gttaccaaat catgaaattg
    94321 gattgatgtt tgaaaaattt gattcatggt ctcgtaatga acttcatatg aaaaatgttg
    94381 taccatatat aacatttaag attgaagatc tgaaaaagaa ttaaagctga aatttgaaaa
    94441 tatataaaaa gaggataaaa attatggtaa attacggtat tgttggagct ggatattttg
    94501 gagctgattt agctcgctca atgaacaaaa ttgaagatgc aaaagtggtt gcggtatttg
    94561 acccaaatca tggagaagaa gttgctcaag agttgggatc agatgtttgt gcaagtttag
    94621 atgaacttgt agcacgtgaa gatattgatt gtgtgatcgt agcttcacct agctaccttc
    94681 accgtgaacc agttgtgaaa gctgctcaac atggcaaaca cgtattttgt gaaaagccaa
    94741 ttgcattgtc ttatgaagat tgtaaagcca tggttgacgc atgtaaagaa aataatgtca
    94801 tctttatggc tggtcacatc atgaacttct ttaacggtgt acaccatgct aaagaattga
    94861 ttactcaagg taaaatcggt aaagttcttt attgccatgc tgctcgtaca ggttgggaag
    94921 aacaacaacc aactgtatca tggaagaaac ttcgttctca atctggagga catttgtacc
    94981 accatattca tgaattagat tgcattcagt ttatcatggg aggacttcct gaaaaagcga
    95041 caatggtagg aggcaatgta tatcataaag gtgaaaactt tggtgatgaa gatgatatgc
    95101 tcattgtaaa cttagaatac tctgatgatc gttatgctgt tttggaatat ggtaatgctt
    95161 tccgttgggg tgaacactac gtcttgattc aaggaactga aggagctatc aaacttgact
    95221 tgttcaatac tggcggtact cttcgtgtta aaggtgaagg agaatcacac ttcttagttc
    95281 atgaaactca agaggaagat gatgatcgta cagctatcta taccggtcgt ggtatggatg
    95341 gagcaattgc gtacggtaaa ccaggagtac gttgcccatt atggttgcaa acatgtattg
    95401 ataaagaaat ggaatatcta catgacatca ttaaaggtgg agaaattaca gaagaatttg
    95461 aaaaacttct caatggtgta gctgctttag aatcaatcgc taccgctgat gcatgtactt
    95521 tatcagttaa agaagatcga aaagtaagtc tttcagaaat cacaaatgct taacttttgt
    95581 aaaacagaat agtaaattct tgtcattata taatttctaa agttctgtga tacaactcat
    95641 tgaataaaga aatagagatg ggactgggat aatgcccagt cccatttttt atcaaaaagt
    95701 aatgagatca aaaatgtggg agtgttgaaa tgaagattat aggtatcgat attggcggaa
    95761 caacaattaa ggcagattta tacgatgagt ttggaacgag tttgaatcat ttcaaagaga
    95821 tagaaacaat tattgactat gatttgggaa cgaatcagat attaaatcag gtctgtgatt
    95881 taattggtga gtatacttta aatcattcaa ttgatggtgt tgggatttcc actgctggag
    95941 ttgttaatgc taatactgga gaaatcatct atgcaggcta tacaatacca gggtatatcg
    96001 gagtaaattt tactgccgaa atagaaaaac gttttgggtt gtatactttt gttgaaaatg
    96061 atgttaattg tgctgcatta ggtgaattgt ggaagggaca agccaaagat aagaaaaatg
    96121 tagtaatggt tactattgga acaggtatag gaggcagtat tattgtcaac ggacaaattg
    96181 ttaacggatt taactatact gctggtgaag taggttatat tcctgtaggt aattcggatt
    96241 ggcaaagtaa agcctcaaca accgcattga ttcatttata tcaaaaaaag agcttgaaaa
    96301 ctaatcaaac tggacgtact ttcttcactg atttaagatc tggagataaa gttgctgaag
    96361 aaacttttga aatttttgta gaaaatctaa caaaaggttt attaacgatt tcttatctac
    96421 ttaatccaga aattctcata ttaggaggtg ggattctgga tagtaaggat attttgttac
    96481 ctgaaattca aagttcttta gctaaaaatg caatggataa taggttttta cctaaaaatc
    96541 ttgtggcagc tacattagga aatgaagctg gtcgtatagg agctgtaaaa aatttcttag
    96601 atagaatttc taataaatag tatgtaagat aaggaggtgt cacaatgact aactctgtat
    96661 tttcgacaat gcaagatatt gagaatgttg caaccgatat tataaaatca tatgataatg
    96721 agatttatac ttataaagct gtttcccaag aagaattgga aaaactagaa aaaagttatg
    96781 atgaaaaaag tcacgaagaa ttagtttcaa tagaaagcaa tttagaaatg aaacaacaga
    96841 accttattga tgaggttaat aaaacaatca aggaaaatga tgcaaatatt cagtatattt
    96901 catcaagtag gagaggagaa tttgtagaaa aaattattgg tagggtggta gaaaaatatg
    96961 gccattagtc agatgaaaag aatctctcta ctattttcta aaagtagtct tgatgatgtt
    97021 ttaaaaacta ttcaagaact agagtcagtg cagttccgtg atttaaaggt tcaggataac
    97081 tggtcagaag ctctagaaaa agatgaagtt gtatttccaa ctattcaaat ttttcatact
    97141 tctaattcca atcatggggt tattgaggga aatgatgcct tgacttattt gatgaatcaa
    97201 caacaacatt tagaagcaac tgtagagaaa ttacaagaat acctaccgaa agaaaacacg
    97261 tttaaattat tgcagcaacc tccgataact acctcttatg aagaattaga gaaatttggt
    97321 aaagctaatg ttgctgaggg tgttcttaaa aaagtgaatc atcaaattaa cagagttcat
    97381 gaattagaaa gacacattca aagtaataat gaggaaatag agcgattaat aaagtgggaa
    97441 aaattagaaa ttgttcctgc gaatttagaa caattttctt tctgtaaagg aaaagtcgga
    97501 acaattccaa ggactgaaga taatcgctta tacaatagtc ttttagaaaa caatattgaa
    97561 gttcaagaaa tattttctaa tgatagagag tacggtgttg ttgttttcta tcagtctagt
    97621 tactctatag attttgatga atacttattt gaaccatttg attattctag aaaggaatta
    97681 ccgaagcagc gagtagtaga tttagatcaa gaaaacatgc agttaataac tgaaaaagag
    97741 aatattatcg catcgttgca agattcaaag aaatatttga tagatttaca atggcaaata
    97801 gactatattt tatctatcta tgctcgtcaa atctctaaga ataacttttt gtgcactccg
    97861 catctagttg cattagaagg atggatagaa gaaactcgta ttttatattt tataaaagtt
    97921 atggatgagc attttggaca ttctatttat atttatgaat cggaaacatt gacggataat
    97981 caagatgaaa tacctatcaa attaacgaat cattctttaa ttgaaccatt tgaattattg
    98041 acagaaatgt atgctctgcc caaatattat gagaaagatc ctacacctgt attagcacca
    98101 ttttacttta cattttttgg aatgatggtt gctgatttag gctatggttt actattgttt
    98161 ttaggaacaa tgttagcatt aaaaattttt catctacctt cagcaactaa gagattttta
    98221 aaattcttta atatattagg ggtagccgtt gcaatttggg gtggaatcta tggctcattt
    98281 tttggatatg agttgccatt tcatctgata tctacaacct ctgatgtcat gactatatta
    98341 gtagtgtcag ttgtgtttgg gtttattaca gtatttgcag gtttgttagc ttcaggacta
    98401 caaaaagtaa gaatgaagaa atatgcagaa gcatataatt caggatttgc gtggtgtgtt
    98461 attctgcttg gcttgttatt tattgctgtt ggaatgttga tgcctgatat gagaccgtta
    98521 tttgtattag ggaaatgggt atctattttt aatgctgtgg ggattttgat tgtttctatt
    98581 attcaaacca aaagcttgtc aggtattgga gcaggattgt ttaatctata taacatttca
    98641 tcttatatag gtgatttagt tagtttcact cgattgatgg cattaggatt atctggagca
    98701 agtatagcat cagctttcaa tttaattgtt ggtttgtttc cgggaatatt ggctaaactg
    98761 acaattggat tagtattatt cattctttta catgcgatca atatttttct atcgttacta
    98821 tcaggatatg ttcatggagc acgtctgata tttgttgaat tttttggtaa gttttatgag
    98881 ggtggaggaa aaccatttca acctttgaag gcttctgaga aatatattaa ggttattaca
    98941 aagaattaat ggaggatata tataatggaa catttagcaa cttatttttc aacctatgga
    99001 ggagctttct tcgctgcatt gggaattgta ttggcggttg gattaagcgg tatggggtct
    99061 gcttatggag ttggtaaggc tgggcaatct gccgcagctt tactgaaaga acagcctgaa
    99121 aagtttgcct cagctttgat attgcaatta ttgcccggaa cacaaggatt atatggtttt
    99181 gttattggaa ttttaatttg gttgcaatta actccagaac ttcctttaga aaaaggcgtt
    99241 gcttatttct ttgtagctct tccaattgct attgtaggat acttttcagc taagcatcaa
    99301 ggaaatgtag cagtagcggg aatgcaaatc ttggctaaaa gaccaaaaga attcatgaag
    99361 ggagcaattt tagctgccat ggtagaaacc tatgcaattc ttgcttttgt cgtatcattc
    99421 attttgaccc ttcgtgtata agaaataaat ttgcaattca aaggaggtgt ctaaatgagc
    99481 aatttagaaa acttacgaga gtctgttatt gaacaagctc atgaaaaagg gcgtatgaaa
    99541 ttattggatt ccaaaaagaa gattgatgat gaatttgaaa tgcaaaagtc gctcattata
    99601 aagaaaaaag aagctgaaca tgaacgaaag ttaaaagaat tgcaacagaa atatcaaata
    99661 atttttcaac aattaaaaaa taaggaacgc caatcaacgt tagtatcaaa acagaaaata
    99721 ttaaaagaac tttttcaatc tgctttacta gaaatggaat cttggagtgc agataaagaa
    99781 atggagttca tctatcgaat tctggaacga tattcacaac aagaggtcat agtaaccttt
    99841 ggggaacgga ctttagctaa attcaatttg gaacaattag agaaattgaa attctctttt
    99901 ccaaattatt tatttagtga acaacctatc tcaaatgaat caggcttact tatttcaata
    99961 ggtaaaattg atgataacta tttgtataaa acattaattg gatcgatttc taaggaagaa
   100021 agttcaagta tcgcaaatca aatttttatc aattaaggat gaaattggtt aatccttctt
   100081 agaaatttgg agtattccaa taaaattaga aaggtatttt atggatacta atcttttttc
   100141 aaaaataaat acgacgattt cggtaaaaga aaacgatttt attacagaag aaaaatttca
   100201 aaaaattata caatccaaag atacggagac attggcattt atcttagaat caactcccta
   100261 tcatttatcg attgacatct tagaagatcc tagtcagaca gagatttcgc taatgacaaa
   100321 attagtcaat gattatagat gggcctatgc tgaaagtccg tctgatataa ttgtgacttt
   100381 atttgcttta cgatatgttt atcataatat caaagtttta ttaaaatcta aggcggcaat
   100441 taagaaagat ttttctaaat tattaattcc aatagggatt tttgatatag aaagtttaaa
   100501 acatttagtt tcttccttac attcagatac acttcctgat tttatggttc gtgaagtaga
   100561 atcaatttgg aatgagtatg aaacttttaa taatattcgt gtacttgatg tcggagctga
   100621 tctagcatat tttaaacatc tgaaactttt atctaatgag ttagatgagg tactgtctca
   100681 ggttattgtc gaaatgattg acttttataa tattattact gtaaaacgtg gtttatctca
   100741 aaataagagt catggggata ttttacaatt actttcagat gaaggaagta tttctgctaa
   100801 agaatttata tacattgtag aaaatcaaga aatatttgtg tggttcaata aaataaatcc
   100861 aagcttagat tcaatctttt caacttatga attgaagatg caggacgcaa caatttcatc
   100921 ttctgagtta gaatttttat gtgatttact attgtataaa actttagatc aaggaaggta
   100981 caatgtagag gggccgttag ttcttgctag atatttattg ggatgtgagt ttgaagtaaa
   101041 gaatctcaga atgatcatat cagctcttca aaatacaatt ccctttgaat caataaaaga
   101101 aaggatacgc ccacattatg gaagctaata agtataaaat tggcataatt ggtagccgtg
   101161 atattatttt accatttagc atgattgggt ttgatatatt tcctgcctac caagaacaag
   101221 aagctataaa tacactaaga aaattagctc aatctgatta tggtgtcatt tatatcactg
   101281 aagacattgc ttcaatgata ttagatacaa ttcgccatta tgattcccaa gttgtgcctg
   101341 ctattatttt attaccgact cataaacaag gtttaaattt aggattaaaa cgtatagagg
   101401 ataatgtaga gaaagcagta ggacacaata ttttataata atgtacaaaa ttgtctgtaa
   101461 tattattcta taatttttgg acttagtaag gagaataact ttgactcaag ggaagattat
   101521 aaaagtatcg ggacctctag ttattgcatc aggtatgcag gaggctaata ttcaagatat
   101581 ttgccgtgta ggtaagctag ggttaatcgg tgaaattatt gaaatgagaa gagatcaggc
   101641 atctatccaa gtctatgaag aaacatctgg tcttggtccg ggagaacctg ttgttacaac
   101701 tggagaacct ctctcggttg aattagggcc aggattgatt tctcaaatgt ttgatggcat
   101761 acaacgccca ttagatcgat ttaaattggc tactcataat gattttctag ttcgtggggt
   101821 agaagttcca agtttggata gagatattaa gtggcatttt gattccacta tagcaattgg
   101881 tcaaaaagtg agtacgggtg atattcttgg aactgtcaag gaaaccgagg tagttaatca
   101941 taaaattatg gttccttatg gagtatctgg agaagtcgtt tctattgcat ctggcgattt
   102001 tacaattgat gaagttgtat atgaaataaa aaaattggac ggtagtttct ataaaggaac
   102061 gcttatgcaa aaatggcctg tccgcaaggc gcgtcctgtt tctaaacgtt taattccaga
   102121 agaaccatta atcacaggtc aacgagttat tgatgcattc tttccagtaa ccaaaggggg
   102181 agctgcagca gttcctggac cgtttggagc aggaaagaca gttgtacaac accaagtagc
   102241 taaatttgcc aatgttgata ttgttattta tgtcggttgt ggagaacgtg gaaatgaaat
   102301 gacggatgta ctgaatgagt ttcctgagtt gattgaccct aataccggac aatcaattat
   102361 gcaacggaca gttctgattg ctaatacttc aaatatgcct gttgctgctc gtgaggcttc
   102421 aatttataca ggaattacca tggctgagta ttttcgtgat atgggctact ctgtcgccat
   102481 tatggctgat tcaacttcac gttgggcaga agcgctacgt gaaatgtcag gacgtctaga
   102541 agaaatgcct ggtgatgagg gttatcctgc ttatctggga agtcgtatcg ctgaatatta
   102601 tgaaagagca ggacgttctc aggttctagg gcttccagaa cgtgaaggaa cgattactgc
   102661 tattggagct gtatcgccac ctggtggaga tatttcagaa ccagttactc aaaacacttt
   102721 acggattgtg aaagtttttt gggggcttga tgctccgttg gcacagcgac gtcattttcc
   102781 tgcaattaac tggcttacat cttattcact atataaagac agtgtgggca cttatataga
   102841 tggtaaagag aagacagatt ggaatagtaa aataactcgt gcgatgaact acttacaacg
   102901 ggaatctagt ttagaggaaa ttgttcgtct tgttggaatt gattctctgt ctgataatga
   102961 acgactaacg atggaaattg ctaaacaaat tcgagaagat tatttgcaac agaacgcttt
   103021 tgattcggta gatacattca cttcgtttgc aaaacaagaa gcaatgctaa gtaatattct
   103081 cacttttgct gatcaggcaa atcatgcttt agagttgggt tcttacttta cagagattat
   103141 ggaaggtacc gtggcagttc gagaccgtat ggcgagaagt aaatatgttt cagaagatag
   103201 attagatgaa atcaaaatta tatcaaatga gattacacat caaattcatt tgatattaga
   103261 aacaggaggt ctataaatga gtgttataaa agaatacaga actgctagtg aagttgttgg
   103321 gcctcttatg attgttgaac aagtaaataa tgtgtcttac aatgagttag ttgaaattca
   103381 acttcataat ggagaaattc gtcgtggaca agttttagag atccacgaag ataaagcaat
   103441 ggttcagctt tttgaaggat ctagtggaat aaatttagaa aagtctaaaa ttcgttttgc
   103501 tggtcatgca ttagaattgg ctgtatctga ggatatggtt ggtcgtattt ttaatgggat
   103561 gggaaaacca attgatggtg gaccagattt aattccagag aaatatttag atattgatgg
   103621 tcaagctatt aatcctgtat ctagagatta tccagatgaa tttattcaga cagggatctc
   103681 ctctattgat catttgaata ctcttgtacg tggtcaaaaa ttaccagtat tttcaggttc
   103741 gggcttacct cataatgaat tagctgctca gatagcaaga caagcgactg ttttaaattc
   103801 tgatgaaaat tttgcggttg tatttgcagc aatgggtatt acttttgaag aagctgagtt
   103861 ttttatggaa gaactcagaa aaacaggagc gatcgatcgt tcggttttat ttatgaactt
   103921 ggcaaatgat cctgcaattg agcgtattgc aactccccgc attgctttaa ctgcggcaga
   103981 gtatctagct tttgaaaaag atatgcacgt tctagttatc atgacggata tgactaacta
   104041 ttgtgaagcg ttacgtgaag tctcggcagc tcgccgtgaa gttccaggga gacgaggcta
   104101 tccgggatat ttatatacaa atttatcaac tctatacgaa agggctggtc gcttagttgg
   104161 taaaaaaggt tcggtgacac agattcctat tttaacaatg ccagaagatg acataacaca
   104221 tccaattcct gatttaactg gatacattac tgaagggcaa attattttgt cgcatgagtt
   104281 gtataatcaa ggttatcgtc caccaatcaa tgttttacct tctctctctc gattaaaaga
   104341 taagggatct ggagaaggta aaactcgtgg agatcatgct ccaactatga atcaactgtt
   104401 tgcagcctat gcccaaggga aaaaggtgga agagttagca gtagtattag gagaatcggc
   104461 tttatctgat gtagataaat tgtatgtgag gtttacaaag cgttttgaag aagagtacat
   104521 aaaccaagga ttttataaaa atcgaaatat agaagatacg ttgaatcttg ggtgggaatt
   104581 actatcaatt cttcctagaa cagagttaaa acgtatcaaa gatgatttgc ttgataaata
   104641 cttacctttg gtagaagttt aatccggaaa tggagtgatt atctatggta cgtttgaatg
   104701 taaaaccaac tcgtatggaa ttgaataact taaaggaacg tttgacaaca gctgaacgtg
   104761 gacataagtt attaaaggat aaaagagatg aattgatgag gcgatttatt tctttgattc
   104821 gtgagaataa tcaacttcgg aaagaagtgg aaagttatct aattgataat ctaaaatcct
   104881 ttgcagttgc taaatcatta aagaattctc aaatggtgga ggaattattt tcaattccat
   104941 cgaaagaaat tgaattattt gttgagaaag aaaatatcat gagtgtaaca gttcctagaa
   105001 tgcatatgaa tattacttct caaaatgaga acagtgaata cagctattta tcttctaata
   105061 gtgaaatgga tgatgtattt gctacaatga atagtttaat ttataaatta ctaagactgg
   105121 cagaagttga aaaaacgtgt cagttaatgg ctgatgaaat agaaaaaaca cgtagacgtg
   105181 taaatggttt agaatactcg attattccaa acttgtcgga aactattcat tatatagaat
   105241 tgaaactaga ggaggcagaa agagccaatt tagttcgtat tatgaaagtg aagtagatcc
   105301 tttatttaga ttattaatta gatgaacaaa tatcagcttg gataaggctt taagcctttc
   105361 taagcttttt ttattgacag tatcaggata tctttttcaa aattttggtt tgttagataa
   105421 tgaaaatgtt tctactaatc tagatttagg attagtaaat cgtaaatgta attatataga
   105481 aagtaagcgc gtcataacaa ggtatctatc attcatggag ctcctcctgt atactattag
   105541 taaagtaaaa ctattggagg atattttaat gccacaacct attgttcctg tagagattcc
   105601 acaatctcgt cgttttgatt ctaaaaagag aaatgatatt ctgcttaaaa ttcgtattgg
   105661 caagcttgaa gtaagttttt ttcaatctct caatctcgaa atggtagaac agcttttgga
   105721 taaggtgttg ctctatgaca attcatctat ctagcctagg ggaggtctat ctcgtgtgtg
   105781 ggaaaactga tatgagacaa ggaatcgatt cactggctta tctggttaaa acccactttg
   105841 aattggatcc tttctccggt caagtctttc tcttttgtgg tggacgtaaa gaccgcttta
   105901 aagtccttta ctgggatggt caaggatttt ggctactata taaacgcttt gagaacggca
   105961 gattgatttg gctaagtaca gaaaaggatg tcaaagctct cacaccagaa caagtagact
   106021 ggcttatgaa gggcttttct atcactccaa aaatatagta gattgaaact agaatagtac
   106081 acctctgctt ctaaaacatt gttagaaatc gattttactg tcctgatcga tttgtcctgt
   106141 tcttatttca ttttactata aatccatcag aaagtcgtga tttctattga aatgaggact
   106201 ttctttttat actcatctgc tttcaaaaag cattctagtc catctccgat taacgatgga
   106261 ctttatcacc tccttctcca gtccttgtat aacatcttgg agttgattca tgacatcttc
   106321 caaagtttaa aaggctttat tcttaaatcc acgtttacga atctctttcc acacttgttc
   106381 aatggggttc atctctggtg tgtatggagg aataa
//
LOCUS       DAVEHY010000002        90625 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVEHY010000002 DAVEHY010000000
VERSION     DAVEHY010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 90625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.002"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..2072)
                     /locus_tag="VUZ44_000115"
     CDS             complement(<1..2072)
                     /locus_tag="VUZ44_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU0319099.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKEIMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEYNDHLEITAYHISDDVMQRSITPVS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSILLDGKHSIVGT
                     WECELVRDNFAITVKKSRGENRGVVITTHKNLKNYQRTKNSQNVVTRIHAKSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKTVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRASGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAK
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRQAGASSSLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKQTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQASGRNLFLNSLFKQDISKTGIWTTSTYTAAIDSESKYLGHKALKIIGLNPSG
                     RDGGNPKVT"
     gene            complement(2073..2795)
                     /locus_tag="VUZ44_000116"
     CDS             complement(2073..2795)
                     /locus_tag="VUZ44_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU0319100.1"
                     /translation="MIKHNELVIDGVRTSSFPFKVIVHDSPSIALGESKTALLEHGGI
                     SGAIVQTNKHRELVKKSYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVTDLEEVQPGLYMTKATFTCHPTKYFKGSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSAVETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            complement(2792..5551)
                     /locus_tag="VUZ44_000117"
     CDS             complement(2792..5551)
                     /locus_tag="VUZ44_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEU0319101.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANRM
                     EAELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAEALDLTSRATRAAADGAAFYDKSIESVTESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFSSLPAPVKDFVVILGTV
                     VTAVGVIAPIFLSLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILEVINAVVSEISNFVMSIFGTVVAWWTENQELIRASAETVWN
                     AIYTVISTILEILGPLIQAGWDNIQLVITTAWEIIKTVVETAINVVLGIIQAVMQIIN
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRKTQL
                     RGGVT"
     gene            complement(5828..6247)
                     /locus_tag="VUZ44_000118"
     CDS             complement(5828..6247)
                     /locus_tag="VUZ44_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319102.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATDIDISMLSDFDMTFFNRLFWIFAKSANPHIKPYEQFFMEME
                     VFPIQEVGPVLMEMLNASMTTKKHQMNQNQLAKKSSQ"
     gene            complement(6259..6837)
                     /locus_tag="VUZ44_000119"
     CDS             complement(6259..6837)
                     /locus_tag="VUZ44_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU0319103.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            complement(6849..7172)
                     /locus_tag="VUZ44_000120"
     CDS             complement(6849..7172)
                     /locus_tag="VUZ44_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319104.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            complement(7169..7516)
                     /locus_tag="VUZ44_000121"
     CDS             complement(7169..7516)
                     /locus_tag="VUZ44_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU0319105.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            complement(7513..7812)
                     /locus_tag="VUZ44_000122"
     CDS             complement(7513..7812)
                     /locus_tag="VUZ44_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEU0319106.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            complement(7799..8080)
                     /locus_tag="VUZ44_000123"
     CDS             complement(7799..8080)
                     /locus_tag="VUZ44_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEU0319107.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            complement(8083..8373)
                     /locus_tag="VUZ44_000124"
     CDS             complement(8083..8373)
                     /locus_tag="VUZ44_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319108.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            complement(8385..9557)
                     /locus_tag="VUZ44_000125"
     CDS             complement(8385..9557)
                     /locus_tag="VUZ44_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEU0319109.1"
                     /translation="MNKALIFGARMRAKATKVVELEETIEELNKRSVVELEKLDRAKN
                     DEEVSAVEKTVDGLQREIEEKEAEKVQLENEIDELDKQIKEQNRKAPTYPSQEKRGGQ
                     KLEQRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTDGVMVSTDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGENTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            complement(9554..10129)
                     /locus_tag="VUZ44_000126"
     CDS             complement(9554..10129)
                     /locus_tag="VUZ44_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEU0319110.1"
                     /translation="MQKRNSYRATQFQTREEESGDLVLSGYFIKFDEETELWRGYHEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFKL"
     gene            complement(10113..11315)
                     /locus_tag="VUZ44_000127"
     CDS             complement(10113..11315)
                     /locus_tag="VUZ44_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU0319111.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDDVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            complement(11333..11551)
                     /locus_tag="VUZ44_000128"
     CDS             complement(11333..11551)
                     /locus_tag="VUZ44_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319112.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            complement(11559..13289)
                     /locus_tag="VUZ44_000129"
     CDS             complement(11559..13289)
                     /locus_tag="VUZ44_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEU0319113.1"
                     /translation="MGNLDKAKEYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVDYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYN
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     SMRERGFKIQAVGMDRKFGREFLAKMKKAKFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQVLANLG
                     KGGDVMRFFD"
     gene            complement(13282..13674)
                     /locus_tag="VUZ44_000130"
     CDS             complement(13282..13674)
                     /locus_tag="VUZ44_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HEU0319114.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYANLGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEILKFKNEIKKKRVPGNG"
     gene            complement(13812..14132)
                     /locus_tag="VUZ44_000131"
     CDS             complement(13812..14132)
                     /locus_tag="VUZ44_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEU0319115.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            complement(14252..14443)
                     /locus_tag="VUZ44_000132"
     CDS             complement(14252..14443)
                     /locus_tag="VUZ44_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319116.1"
                     /translation="MIKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKRGNFFKESE"
     gene            complement(14608..15150)
                     /locus_tag="VUZ44_000133"
     CDS             complement(14608..15150)
                     /locus_tag="VUZ44_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU0319117.1"
                     /translation="MEFVSPIKDNDDIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            complement(15341..15742)
                     /locus_tag="VUZ44_000134"
     CDS             complement(15341..15742)
                     /locus_tag="VUZ44_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU0319118.1"
                     /translation="MKKLSDEDLKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     SVGISKPTETIAVRIADDPTLKFLEGFKAIINKLLINLVDEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAILKGEL"
     gene            complement(15879..16277)
                     /locus_tag="VUZ44_000135"
     CDS             complement(15879..16277)
                     /locus_tag="VUZ44_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319119.1"
                     /translation="MIPKFRVWDRARNEMNYKVMVGNCDTDDENWTCPIIWIEEEKDW
                     LHFDDYECIMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTYIGGMPAVYL
                     KGFGDGYAWTEYEEIIGNVYENPELLEVNE"
     gene            complement(16274..16759)
                     /locus_tag="VUZ44_000136"
     CDS             complement(16274..16759)
                     /locus_tag="VUZ44_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEU0319120.1"
                     /translation="MNLEEKVQQWFVDRDLENGGRLDKQSLKLSEEFGELCAGYLKKN
                     EQLTKDSIGDCAVVIVGLALLIKKDVHKIFKTSGNDRDVMTCFVFLNQNISEFQLCQD
                     FGDNGILELYLSRTIYWLKSLSIALGYNFEECFELAYQEIKDRKGRWIDGTFVKEEDL
                     A"
     gene            complement(17040..17501)
                     /locus_tag="VUZ44_000137"
     CDS             complement(17040..17501)
                     /locus_tag="VUZ44_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU0319121.1"
                     /translation="MGDIRILDACCGSRMFWFDKNESHTIFMDIRQETFEIHDKKVNV
                     DPDIIGDFRDMPFDDEIFNLVVFDPPHLLWAGQKSFMRAQYGQLDLLTWRLDLQQGFE
                     ECFRVLKSGGTLIFKWSDAQVNVKEILELVPHQPLFGQQRGTTHWMAFMKF"
     gene            complement(17501..17788)
                     /locus_tag="VUZ44_000138"
     CDS             complement(17501..17788)
                     /locus_tag="VUZ44_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319122.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEEVE"
     gene            complement(17788..18291)
                     /locus_tag="VUZ44_000139"
     CDS             complement(17788..18291)
                     /locus_tag="VUZ44_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU0319123.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELARQIFLQDLEQLDKPKPVKV
                     PQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLNGYEVEKE
                     KRYLVKIKGNIKENMLVYGELLERYFFTKSFSLDDAIYSHTRKELENAKIGWVFDCEG
                     FEIEEVE"
     gene            complement(18281..18610)
                     /locus_tag="VUZ44_000140"
     CDS             complement(18281..18610)
                     /locus_tag="VUZ44_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319124.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGSTKDWLPKSKEFDDWIGYSPSMAQVVIAVYLIY
                     RGSEDET"
     gene            complement(18582..18791)
                     /locus_tag="VUZ44_000141"
     CDS             complement(18582..18791)
                     /locus_tag="VUZ44_000141"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319125.1"
                     /translation="MNYDKRTVIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKAEELEDDGRVKAKS"
     gene            complement(18781..18945)
                     /locus_tag="VUZ44_000142"
     CDS             complement(18781..18945)
                     /locus_tag="VUZ44_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319126.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEL"
     gene            complement(19225..19419)
                     /locus_tag="VUZ44_000143"
     CDS             complement(19225..19419)
                     /locus_tag="VUZ44_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319127.1"
                     /translation="MFILKHGTREDKPFLMSAVIGVTGLDISCSEEKKAMRFVSRGAA
                     VQVGKALRGSFGNFYPIEVE"
     gene            complement(19434..20204)
                     /locus_tag="VUZ44_000144"
     CDS             complement(19434..20204)
                     /locus_tag="VUZ44_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU0319128.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLTS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(20198..20356)
                     /locus_tag="VUZ44_000145"
     CDS             complement(20198..20356)
                     /locus_tag="VUZ44_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319129.1"
                     /translation="MGVLELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            complement(20344..21150)
                     /locus_tag="VUZ44_000146"
     CDS             complement(20344..21150)
                     /locus_tag="VUZ44_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU0319130.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALEEDKDKNKNRLDK
                     DKNKKRITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENDVDLVKEALKTAI
                     NSGKPNIKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            complement(21143..21439)
                     /locus_tag="VUZ44_000147"
     CDS             complement(21143..21439)
                     /locus_tag="VUZ44_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319131.1"
                     /translation="MEELIEWLDNLIMIVKELEGRESTSRHFITIWENDYKNLLLVKE
                     YLTDYEKLAKDYRYVTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            complement(21455..21775)
                     /locus_tag="VUZ44_000148"
     CDS             complement(21455..21775)
                     /locus_tag="VUZ44_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319132.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIRGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRFL"
     gene            complement(21861..22118)
                     /locus_tag="VUZ44_000149"
     CDS             complement(21861..22118)
                     /locus_tag="VUZ44_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU0319133.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(22131..22841)
                     /locus_tag="VUZ44_000150"
     CDS             complement(22131..22841)
                     /locus_tag="VUZ44_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEU0319134.1"
                     /translation="MNEIFNFHGQEVRTLTIDNEPWFVGKDVADILGYSKARNAIALH
                     VDEEDALKQGIPTSGGTQDMLIINESGLYSLILSSKLLQAKEFKRWVTSEVLPAIRKQ
                     GGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKAR
                     VVACLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTWE
                     PSTNTKMKIMELNSFDEG"
     gene            22895..23320
                     /locus_tag="VUZ44_000151"
     CDS             22895..23320
                     /locus_tag="VUZ44_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319135.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            complement(23315..23476)
                     /locus_tag="VUZ44_000152"
     CDS             complement(23315..23476)
                     /locus_tag="VUZ44_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319136.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(23487..23684)
                     /locus_tag="VUZ44_000153"
     CDS             complement(23487..23684)
                     /locus_tag="VUZ44_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319137.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            complement(23701..23904)
                     /locus_tag="VUZ44_000154"
     CDS             complement(23701..23904)
                     /locus_tag="VUZ44_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU0319138.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVTSSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            23959..24441
                     /locus_tag="VUZ44_000155"
     CDS             23959..24441
                     /locus_tag="VUZ44_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319139.1"
                     /translation="MKSSFFHYLKEIILYGVLVPILTVIVGFHLFTTFYPISDSLLTD
                     FLKAFTEQRILAIVFVLILCFIFFGSIYYCISCGRNRKLIPDKVYTQITTYISSVGLG
                     TAVIAVATLTLTELQFSILTGWIAFIALLLPLLKFKVQYSTYQSSDNVAQKTTENKAN
                     "
     gene            24747..25115
                     /locus_tag="VUZ44_000156"
     CDS             24747..25115
                     /locus_tag="VUZ44_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319140.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            25115..25348
                     /locus_tag="VUZ44_000157"
     CDS             25115..25348
                     /locus_tag="VUZ44_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319141.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            25348..25611
                     /locus_tag="VUZ44_000158"
     CDS             25348..25611
                     /locus_tag="VUZ44_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU0319142.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            25624..26004
                     /locus_tag="VUZ44_000159"
     CDS             25624..26004
                     /locus_tag="VUZ44_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEU0319143.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLAPE
                     QQIQVALHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEVMVKEEYLALVN"
     gene            26042..26869
                     /locus_tag="VUZ44_000160"
     CDS             26042..26869
                     /locus_tag="VUZ44_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU0319144.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETEAIETKTTETEHIEQNIVSDSVADIVNEI
                     NLSETSPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            27044..28192
                     /locus_tag="VUZ44_000161"
     CDS             27044..28192
                     /locus_tag="VUZ44_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU0319145.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(28630..29046)
                     /locus_tag="VUZ44_000162"
     CDS             complement(28630..29046)
                     /locus_tag="VUZ44_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0319146.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(29058..29743)
                     /locus_tag="VUZ44_000163"
                     /pseudo
     CDS             complement(29058..29743)
                     /locus_tag="VUZ44_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(29937..32438)
                     /locus_tag="VUZ44_000164"
     CDS             complement(29937..32438)
                     /locus_tag="VUZ44_000164"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU0319147.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            complement(32893..33981)
                     /locus_tag="VUZ44_000165"
     CDS             complement(32893..33981)
                     /locus_tag="VUZ44_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU0319148.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(33999..34667)
                     /locus_tag="VUZ44_000166"
     CDS             complement(33999..34667)
                     /locus_tag="VUZ44_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU0319149.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SSSI"
     gene            complement(34686..37124)
                     /locus_tag="VUZ44_000167"
     CDS             complement(34686..37124)
                     /locus_tag="VUZ44_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU0319150.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(37275..38573)
                     /locus_tag="VUZ44_000168"
     CDS             complement(37275..38573)
                     /locus_tag="VUZ44_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU0319151.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            complement(38590..38898)
                     /locus_tag="VUZ44_000169"
     CDS             complement(38590..38898)
                     /locus_tag="VUZ44_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU0319152.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(38944..39264)
                     /locus_tag="VUZ44_000170"
     CDS             complement(38944..39264)
                     /locus_tag="VUZ44_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU0319153.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(39459..40439)
                     /locus_tag="VUZ44_000171"
     CDS             complement(39459..40439)
                     /locus_tag="VUZ44_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU0319154.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKESSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(40452..41198)
                     /locus_tag="VUZ44_000172"
     CDS             complement(40452..41198)
                     /locus_tag="VUZ44_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU0319155.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNMATLENAGIMVKVVS"
     gene            41320..42096
                     /locus_tag="VUZ44_000173"
     CDS             41320..42096
                     /locus_tag="VUZ44_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU0319156.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            42171..42368
                     /locus_tag="VUZ44_000174"
     CDS             42171..42368
                     /locus_tag="VUZ44_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU0319157.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSSLSDISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            42585..43181
                     /locus_tag="VUZ44_000175"
                     /pseudo
     CDS             42585..43181
                     /locus_tag="VUZ44_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            43257..43706
                     /locus_tag="VUZ44_000176"
                     /pseudo
     CDS             43257..43706
                     /locus_tag="VUZ44_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            43719..44810
                     /locus_tag="VUZ44_000177"
     CDS             43719..44810
                     /locus_tag="VUZ44_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319158.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQTIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            44800..46435
                     /locus_tag="VUZ44_000178"
                     /pseudo
     CDS             44800..46435
                     /locus_tag="VUZ44_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(46538..47230)
                     /locus_tag="VUZ44_000179"
     CDS             complement(46538..47230)
                     /locus_tag="VUZ44_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU0319159.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(47474..48811)
                     /locus_tag="VUZ44_000180"
     CDS             complement(47474..48811)
                     /locus_tag="VUZ44_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU0319160.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(48821..49087)
                     /locus_tag="VUZ44_000181"
     CDS             complement(48821..49087)
                     /locus_tag="VUZ44_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU0319161.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAIVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(49352..49738)
                     /gene="rplQ"
                     /locus_tag="VUZ44_000182"
     CDS             complement(49352..49738)
                     /gene="rplQ"
                     /locus_tag="VUZ44_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU0319162.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(49750..50685)
                     /locus_tag="VUZ44_000183"
     CDS             complement(49750..50685)
                     /locus_tag="VUZ44_000183"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU0319163.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(50728..51111)
                     /gene="rpsK"
                     /locus_tag="VUZ44_000184"
     CDS             complement(50728..51111)
                     /gene="rpsK"
                     /locus_tag="VUZ44_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU0319164.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(51129..51494)
                     /gene="rpsM"
                     /locus_tag="VUZ44_000185"
     CDS             complement(51129..51494)
                     /gene="rpsM"
                     /locus_tag="VUZ44_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU0319165.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(51512..51628)
                     /gene="rpmJ"
                     /locus_tag="VUZ44_000186"
     CDS             complement(51512..51628)
                     /gene="rpmJ"
                     /locus_tag="VUZ44_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU0319166.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(51653..51871)
                     /gene="infA"
                     /locus_tag="VUZ44_000187"
     CDS             complement(51653..51871)
                     /gene="infA"
                     /locus_tag="VUZ44_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU0319167.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(51988..52626)
                     /locus_tag="VUZ44_000188"
     CDS             complement(51988..52626)
                     /locus_tag="VUZ44_000188"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU0319168.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAQALDKTLA
                     ELGIELEGVINIEVNPNSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(52777..54087)
                     /gene="secY"
                     /locus_tag="VUZ44_000189"
     CDS             complement(52777..54087)
                     /gene="secY"
                     /locus_tag="VUZ44_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU0319169.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(54100..54540)
                     /gene="rplO"
                     /locus_tag="VUZ44_000190"
     CDS             complement(54100..54540)
                     /gene="rplO"
                     /locus_tag="VUZ44_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU0319170.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(54685..54909)
                     /gene="rpmD"
                     /locus_tag="VUZ44_000191"
     CDS             complement(54685..54909)
                     /gene="rpmD"
                     /locus_tag="VUZ44_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU0319171.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(54881..55375)
                     /gene="rpsE"
                     /locus_tag="VUZ44_000192"
     CDS             complement(54881..55375)
                     /gene="rpsE"
                     /locus_tag="VUZ44_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU0319172.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(55393..55749)
                     /gene="rplR"
                     /locus_tag="VUZ44_000193"
     CDS             complement(55393..55749)
                     /gene="rplR"
                     /locus_tag="VUZ44_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU0319173.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(55833..56369)
                     /gene="rplF"
                     /locus_tag="VUZ44_000194"
     CDS             complement(55833..56369)
                     /gene="rplF"
                     /locus_tag="VUZ44_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU0319174.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(56561..56959)
                     /gene="rpsH"
                     /locus_tag="VUZ44_000195"
     CDS             complement(56561..56959)
                     /gene="rpsH"
                     /locus_tag="VUZ44_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU0319175.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(57244..57513)
                     /gene="rpsN"
                     /locus_tag="VUZ44_000196"
     CDS             complement(57244..57513)
                     /gene="rpsN"
                     /locus_tag="VUZ44_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU0319176.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(57531..58073)
                     /gene="rplE"
                     /locus_tag="VUZ44_000197"
     CDS             complement(57531..58073)
                     /gene="rplE"
                     /locus_tag="VUZ44_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU0319177.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(58097..58402)
                     /gene="rplX"
                     /locus_tag="VUZ44_000198"
     CDS             complement(58097..58402)
                     /gene="rplX"
                     /locus_tag="VUZ44_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU0319178.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIVEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(58480..58848)
                     /gene="rplN"
                     /locus_tag="VUZ44_000199"
     CDS             complement(58480..58848)
                     /gene="rplN"
                     /locus_tag="VUZ44_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU0319179.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(58874..59134)
                     /gene="rpsQ"
                     /locus_tag="VUZ44_000200"
     CDS             complement(58874..59134)
                     /gene="rpsQ"
                     /locus_tag="VUZ44_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU0319180.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(59159..59365)
                     /locus_tag="VUZ44_000201"
     CDS             complement(59159..59365)
                     /locus_tag="VUZ44_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU0319181.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(59375..59788)
                     /gene="rplP"
                     /locus_tag="VUZ44_000202"
     CDS             complement(59375..59788)
                     /gene="rplP"
                     /locus_tag="VUZ44_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU0319182.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(59792..60445)
                     /gene="rpsC"
                     /locus_tag="VUZ44_000203"
     CDS             complement(59792..60445)
                     /gene="rpsC"
                     /locus_tag="VUZ44_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU0319183.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(60458..60802)
                     /gene="rplV"
                     /locus_tag="VUZ44_000204"
     CDS             complement(60458..60802)
                     /gene="rplV"
                     /locus_tag="VUZ44_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU0319184.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(60814..61095)
                     /gene="rpsS"
                     /locus_tag="VUZ44_000205"
     CDS             complement(60814..61095)
                     /gene="rpsS"
                     /locus_tag="VUZ44_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU0319185.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(61199..62032)
                     /gene="rplB"
                     /locus_tag="VUZ44_000206"
     CDS             complement(61199..62032)
                     /gene="rplB"
                     /locus_tag="VUZ44_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU0319186.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(62050..62346)
                     /locus_tag="VUZ44_000207"
     CDS             complement(62050..62346)
                     /locus_tag="VUZ44_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU0319187.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(62346..62969)
                     /gene="rplD"
                     /locus_tag="VUZ44_000208"
     CDS             complement(62346..62969)
                     /gene="rplD"
                     /locus_tag="VUZ44_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU0319188.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(62994..63620)
                     /gene="rplC"
                     /locus_tag="VUZ44_000209"
     CDS             complement(62994..63620)
                     /gene="rplC"
                     /locus_tag="VUZ44_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU0319189.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(63837..64145)
                     /gene="rpsJ"
                     /locus_tag="VUZ44_000210"
     CDS             complement(63837..64145)
                     /gene="rpsJ"
                     /locus_tag="VUZ44_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU0319190.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(64412..65029)
                     /locus_tag="VUZ44_000211"
     CDS             complement(64412..65029)
                     /locus_tag="VUZ44_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU0319191.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(65026..65616)
                     /gene="nrdG"
                     /locus_tag="VUZ44_000212"
     CDS             complement(65026..65616)
                     /gene="nrdG"
                     /locus_tag="VUZ44_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU0319192.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            complement(65609..66067)
                     /locus_tag="VUZ44_000213"
     CDS             complement(65609..66067)
                     /locus_tag="VUZ44_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0319193.1"
                     /translation="MMTEFEKSQSAHDGGFWDTENFVYEEWLETNIQKEMGINLPENR
                     VPSIQFVLFGESGCALRFLNLRLRLNERLLNYAGHIGYSIRPSEKGKGYAKETLRQGL
                     QVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVERYWIEVANE"
     gene            complement(66160..66300)
                     /locus_tag="VUZ44_000214"
     CDS             complement(66160..66300)
                     /locus_tag="VUZ44_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319194.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(66312..68519)
                     /gene="nrdD"
                     /locus_tag="VUZ44_000215"
     CDS             complement(66312..68519)
                     /gene="nrdD"
                     /locus_tag="VUZ44_000215"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU0319195.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLDDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(68639..70177)
                     /locus_tag="VUZ44_000216"
     CDS             complement(68639..70177)
                     /locus_tag="VUZ44_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU0319196.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQTKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDTIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(70214..70357)
                     /locus_tag="VUZ44_000217"
     CDS             complement(70214..70357)
                     /locus_tag="VUZ44_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319197.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(70435..71967)
                     /gene="cls"
                     /locus_tag="VUZ44_000218"
     CDS             complement(70435..71967)
                     /gene="cls"
                     /locus_tag="VUZ44_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU0319198.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(72113..72643)
                     /locus_tag="VUZ44_000219"
     CDS             complement(72113..72643)
                     /locus_tag="VUZ44_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU0319199.1"
                     /translation="MTPLFELVILGKLLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTG
                     QDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIV
                     VDDMDRDPSDQIVLTK"
     gene            complement(72640..73890)
                     /locus_tag="VUZ44_000220"
     CDS             complement(72640..73890)
                     /locus_tag="VUZ44_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU0319200.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLHPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(74302..74607)
                     /locus_tag="VUZ44_000221"
     CDS             complement(74302..74607)
                     /locus_tag="VUZ44_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU0319201.1"
                     /translation="MSHDHNHDHEERELITLVDEEGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(74623..75042)
                     /gene="ruvX"
                     /locus_tag="VUZ44_000222"
     CDS             complement(74623..75042)
                     /gene="ruvX"
                     /locus_tag="VUZ44_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU0319202.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGKFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(75046..75312)
                     /locus_tag="VUZ44_000223"
     CDS             complement(75046..75312)
                     /locus_tag="VUZ44_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU0319203.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(75399..75968)
                     /locus_tag="VUZ44_000224"
     CDS             complement(75399..75968)
                     /locus_tag="VUZ44_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU0319204.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(76034..76432)
                     /gene="spx"
                     /locus_tag="VUZ44_000225"
     CDS             complement(76034..76432)
                     /gene="spx"
                     /locus_tag="VUZ44_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU0319205.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            complement(76564..77625)
                     /locus_tag="VUZ44_000226"
     CDS             complement(76564..77625)
                     /locus_tag="VUZ44_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU0319206.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            complement(77618..80449)
                     /gene="uvrA"
                     /locus_tag="VUZ44_000227"
     CDS             complement(77618..80449)
                     /gene="uvrA"
                     /locus_tag="VUZ44_000227"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU0319207.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKNVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVTNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            complement(81001..81210)
                     /locus_tag="VUZ44_000228"
     CDS             complement(81001..81210)
                     /locus_tag="VUZ44_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319208.1"
                     /translation="MAKVKEKWNPTISHIVPKGTKLSDGTILDKETTLTQEEFTKNPP
                     VIPAGHPYYNLLARISREEIEKEDL"
     gene            complement(81958..82377)
                     /locus_tag="VUZ44_000229"
     CDS             complement(81958..82377)
                     /locus_tag="VUZ44_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU0319209.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELEALEGGIIQKPTLSHSR
                     VQTSRENKTENNFISVLKLKEDTLQRIERITEERMEISGLIDKLANPLERSVLRLFYL
                     NDLDIWGVAEEIGKSKASIYRAKKAAIEHLACMVNGN"
     gene            complement(83524..84054)
                     /locus_tag="VUZ44_000230"
     CDS             complement(83524..84054)
                     /locus_tag="VUZ44_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319210.1"
                     /translation="MTLKTFSDKAKTFTFTYEFKDLDTAMVAGHALLGYMTGTYEVPS
                     ISITHKDKGTLVAEYVEDHKLNKTFKRICDSFKDYYNQLVDDEAFEERYKRERVLQLK
                     ESEDFESLLEKVTDYELELLDYADRLLSDKPIPMDSMTAFGTLEMLGDESISLIQKLD
                     VEGEYKGLAVYTEHLK"
     gene            complement(84417..85892)
                     /locus_tag="VUZ44_000231"
     CDS             complement(84417..85892)
                     /locus_tag="VUZ44_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEU0319211.1"
                     /translation="MEVREQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVT
                     EKVAMPQTFTVAKILSEIVTFTFISKINIPDYSLLYIYDLDEGIYTASNDLFNLLCKT
                     FDVRIKPREWPQIKLMVRTLVKIRKPLESANLIPVQNGIINLETKELLPFSPKYVITS
                     KISTAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAI
                     FYGDGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYL
                     KNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVP
                     FNADFNGEKEKPWIKNEFLANDEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDN
                     DYLLSWVKHEYMEKGWHELDVVPVFILTRSLKHYAEDMGIPKPNVYGAGKETIRHLQQ
                     LTPNHYKLKRARVKVEDYDKLDPLEFERTKLSKTNHAVVKD"
     gene            complement(85936..86802)
                     /locus_tag="VUZ44_000232"
     CDS             complement(85936..86802)
                     /locus_tag="VUZ44_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEU0319212.1"
                     /translation="MTIYETRGFQGNLVYPFDKIEPFQYIERFKPLVVPEGANIEEFK
                     RTQAPYCISGKVTPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTSEGFIKDVSSTLFGY
                     SYILYPTIKHNLEKPRFRLVVKPDNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDLASYQKIVEHGLDYPVPQTTAEPVKQNATSLPYTPRPSGQKSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTF
                     SSIARAEYRKRG"
     gene            complement(86943..87218)
                     /locus_tag="VUZ44_000233"
     CDS             complement(86943..87218)
                     /locus_tag="VUZ44_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU0319213.1"
                     /translation="MFSLSRESEQDLAQGILEVVERYLEARDRLKPRLTGLISAQEVM
                     DELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYRISDIWKFMGVENG"
     gene            complement(87211..87552)
                     /locus_tag="VUZ44_000234"
     CDS             complement(87211..87552)
                     /locus_tag="VUZ44_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU0319214.1"
                     /translation="MSLSDNDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LITRYGVPIVGVRHGTFRGYFIPANKEELLDGAKAFYNQVQEEQKRLTILLNADLESY
                     KETLKEVGGYV"
     gene            complement(87549..87764)
                     /locus_tag="VUZ44_000235"
     CDS             complement(87549..87764)
                     /locus_tag="VUZ44_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319215.1"
                     /translation="MNELDLTNTQSVIFMVVLIGLLLYLNHRDRKKSTQFERENQRTI
                     ETPSEDLNPDYGRYIQLAGVNVWGGTE"
     gene            complement(87766..87966)
                     /locus_tag="VUZ44_000236"
     CDS             complement(87766..87966)
                     /locus_tag="VUZ44_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319216.1"
                     /translation="MTLDLDNMTQAEFDEVMAEIKAKRPNLFQFIADFVDRKVSTEEV
                     DEYLKMKHEKQVEFIKSYQARA"
     gene            complement(87963..88415)
                     /locus_tag="VUZ44_000237"
     CDS             complement(87963..88415)
                     /locus_tag="VUZ44_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319217.1"
                     /translation="MTETTYENLTRHIDRISAEMREIGEKNGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSHKIEAVSKSTTGMFFHAGIFEMDAMRQAFFKRQAMHFFDNEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            complement(88849..89425)
                     /locus_tag="VUZ44_000238"
                     /pseudo
     CDS             complement(88849..89425)
                     /locus_tag="VUZ44_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424669.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(89440..89640)
                     /locus_tag="VUZ44_000239"
     CDS             complement(89440..89640)
                     /locus_tag="VUZ44_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU0319218.1"
                     /translation="MSKLRGYRVMLGLTQQQMADKLKISLQSYNNKELGKTPFNDKER
                     LAIKSMVAEIKSDITIDELFYS"
     gene            89846..90361
                     /locus_tag="VUZ44_000240"
     CDS             89846..90361
                     /locus_tag="VUZ44_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319219.1"
                     /translation="MNRLKELRQEKKLSQKELAENIGVHYRTLQNWENGESQIKPEKA
                     QQLADYFGVSVGYLLGYSEYRELEKALDKTIFSNYPDVETFLTQEIKELIGERTKDFY
                     EYIDKQFYESYKNTTVPPEIVVKHREDFYSSFLFLPARLQKFIALWSILTETEQENIG
                     KTIELLAMRGR"
BASE COUNT        26001 a        20041 c        15847 g        28736 t
ORIGIN      
        1 gtaaccttgg gattacctcc atcacggcca gatggattca gacctataat tttaagagcc
       61 ttgtgtccaa gatacttact ttcgctatcg atagcagccg tatatgtact cgttgtccaa
      121 attcctgttt ttgaaatatc ctgcttgaat agtgagttca agaatagatt tcgaccggat
      181 gcctgcacac tcgcaatccg actagctagc tcctcagctg tctgcgtaag ttctgacttg
      241 ctggctttac cattggccaa gttggtcagt tctgacagtc tacgagtcgt cgtctcctta
      301 tacgtcgctt gcgctgactt cacgccagcc agttcattct tagtccggct aagtgcttca
      361 acttgcttgg caatctcagc ttcagcctgt gcttgcttcg gtcgaatatc gtttgcgata
      421 gtttgtttta gaacatccaa gtcacctgac aaagccgtct gagcgctcgt agtctgcgac
      481 ttaaacgctt caagtctagc aacagaatcc agctcaatcc gcttagcttc ctgtgcaagt
      541 agggtacttg cgccagccag ttcattttta gtccggctaa gtgcttcagc ttgcttggca
      601 atctcagctt cagcctgtgc ttgcttcggt cgaatatcat tcgcgatagt ccgtttcaga
      661 gcgtccaagt cacctgacag agccgtttgt gcgctcgtag tctgcgactt aaacgcttca
      721 agtctagcaa cagaatccag cccaatccgc ttggcttcct gagcaagaga gctacttgcg
      781 ccagcttgtc tcaaagcttc ctcagccttg cgcttagttt ctttcaatgg cccgttgtca
      841 aagctattaa agcgctgatt gatagtgtca gacagttctc gcttgacttc ttccgccttg
      901 gccttggcaa gttcaatatc gtcagaaatt tcctgtctaa gcaatccagc cttatgatca
      961 aagtctaagt cagcattttg aagagccttt tcaagggcga tttcttgtgc agattctgtc
     1021 actccaagaa ttgcatcggc tgcgctagat aggccaccag aagctctaga accaccaata
     1081 cctgccttat catcgaaagt cagagagatg tattcttctt ttaaggcatc gaactcataa
     1141 gcaatagctt tcttgaatgc atcgacatta tgtttccagc tcttgagatt gaccgtgtcg
     1201 cccatatgga ccacttgccc atcaagttca taagcttcaa tcttgatagc atcagagacc
     1261 ttgtcaattc cctcatttga gaacttagac tgtgcccact tctgcaactc ttcaacagtt
     1321 ttagcattgt tgttctcata ctctttttca ttgatataag ggtatgagtt gataagagga
     1381 ctatcaacag tcactctgat agtcgtttct ttttcagcac cttcaggttt aaaagtcgac
     1441 tttgcgtgaa ttcttgtgac aacattctga ctgttttttg tgcgttggta gttcttcaga
     1501 tttttgtgcg ttgtaataac aacaccacga ttctccccac gactcttctt gacagttatc
     1561 gcaaagttat cacgaaccag ctcgcattcc catgtaccaa caatgctgtg cttaccgtcc
     1621 agcaatatag agtatagggt ttctgtttca gtcgtattga aggtcctacg gtcctggata
     1681 tcactgttga atgagaagtc tccaagagcc gttttggtgt tttgtaccat gcgagaaaga
     1741 gccatgccac aactctgact agtcacactt actggtgtga tagaacgttg catcacatcg
     1801 tctgaaatgt gataggctgt gatttccaga tgatcattgt attcaacagg tttcttaatg
     1861 cgaaatagct gcgcaccaag aacaggagtc ggcgctttta tcaacatatc ttcttggatg
     1921 agctgataaa taccagagtc ggaaatggga tatttcacag ttaaggtgaa atcaccattc
     1981 atgatctctt taacaatcgc cgaagtcgct tcatgaagtg gctccccgtt ccatcgaacg
     2041 gttcttacat ctttattaag tagataaagc aattatgccc acccccaaac cgtttcgatt
     2101 tcaatcgatt gaatacctgg gcctaaaaca accccaatat tcttaacttt cgctggatca
     2161 actgtgataa aatcccctga ccatttgact ggcttccctg ttgtcgtttt aaagctagga
     2221 ttgtcaggat tattaaccat cacaagcgat tctgagagtt tttcaagcct aatgacctga
     2281 ccagcgattg taaatgaagt ctcaacagcg ctctgaccaa cgattgtgat tttaggaaaa
     2341 gcaagagcag aaccttgaac ggtcaaggtt ccacttcttg tcaatctctg tgtatcggag
     2401 cctttaaagt attttgtagg atggcaagtg aaggtcgctt tggtcatgta aagaccaggt
     2461 tgtacttctt caaggtcagt cacattgacc ttatagcacc agagacgagt tgttttgact
     2521 cgctcgctct ctaaccagaa cttctcacgg ataaacagac tcataaattg gttcatctgc
     2581 tcctcagtcg gtttgactaa gtaaatcgta taagatttct tgaccagttc cctgtgcttg
     2641 ttcgtctgaa caattgcccc actgatacca ccatgctcca aaagagctgt cttgctctct
     2701 cccagagcaa ttgaaggaga atcatggaca atgactttaa acggaaaaga cgatgttctc
     2761 acaccgtcaa tcacaagctc attatgcttt atcatgtaac ccctcctctc aattgtgtct
     2821 tacgttgcaa ctcgtcagca atacgctgag ccacctcatc agcaatacga ctgatgtcgg
     2881 cttcttctct gacagtgttg ccagtaatgg taatgttaat ggttggtgaa gttccaccca
     2941 tagtttgagc gatacctcga ccgatggctc caagcgtttt gtcgttaagt ggcaatactg
     3001 cttcattccc agcttcacca ccaaccatta tgttattacc attcattcca aagatagttg
     3061 gtttcgtcat gataccgcct ttggcatacc attcgattcc aatacttgga acaccttgac
     3121 tcaaccaatc taatggattg gccgaaccac tcacgtaaaa gtgaggtagt gggatatgtg
     3181 gccagctgat gttgaagtta aacaatcctt tgatggcttc aatagctgaa gaaacagcat
     3241 cccttgcacc attgatagca cttgaaatgg tactcttgat accttcccaa acacttgata
     3301 cagtactaga tatagcattt aacacatttg agacagtgtc cttgatgctg ttccagatat
     3361 ttgatacagt tcctgaaatg ccgttgagaa tatttgaaat ataactctgg atagctgaaa
     3421 aaatggtctg tacaatgctt tggatagctt gccatacagt agagaatacc cccttaatag
     3481 tttcccaagc gcctgaccaa tcaccattga tgatctgcat aactgcttga atgataccaa
     3541 ggacaacgtt tattgcagtc tcaacaacag tcttaatgat ttcccaagct gttgtaatga
     3601 caagttggat attatcccaa ccagcttgaa tgagtggacc taaaatttcc agaattgtgc
     3661 ttataaccgt atagatagca ttccagacag tctcagcact tgctcgaata agttcctggt
     3721 tctccgtcca ccaagcaaca accgttccaa agatactcat gacaaaatta gaaatctctg
     3781 atacgactgc attgataact tcaagaatcg cattccaaac ggtcgtgacc gcatctcgaa
     3841 aaccttcgtt agtttcccag agatatttta caataacaat aattgcagca actgcagcag
     3901 caattgcaat agctgttcca ataattggca atgcggcaat tatcatttct ccaatagata
     3961 tttttaaaaa ctcagcaagg gcttgcaacg ataagaatat gggggctatg acccctacag
     4021 cagtcacaac tgttcctaaa ataacaacaa aatcttttac tggagcaggt aaggaactga
     4081 acagctcagc tacacctttc acaatcgttg ccaaggtttg aaaaacagga atcatcattt
     4141 ctagaagagg ttgaccaata gcagataatg cattggtccc agcttgtttc agattcccca
     4201 tcacgttttc caggccgtct gattctcttg cagcctgtcc aagagctcct gagagtttat
     4261 ttccgtcttc gaccatctga agcaaggtca attgcttctg cgcttcgctc aagtccttga
     4321 atgactttcc gtacaattta tttgcagcgg cattcctggt cgtttctgtt gcagaaatgc
     4381 caagagccgc atcgttagca aagtttccct tcaaaaaaga ttgtaagctc tctgtcacgc
     4441 tctcaataga tttgtcatag aaggctgcac cgtctgctgc tgccctagtt gcacgagaag
     4501 taagatccaa agcttctgct gtatccaatc ctgaagtttt tgcaaatgaa gccatctgag
     4561 tgaatgatcc ttgcaatcgc tctgggacaa tatccatttc ctgaccaata gcattcaacg
     4621 cttctcttgc ttgggtttcc atatctccga aaacggtagt aaattgagca ttactagctt
     4681 gcatttgagc agctgcttct aacgcttctt ttcctacttc cacaagcttt tctgaaatag
     4741 cactcaactt ctcactaaac tgttgaagta gttctgctct taaatttctt gagatttcac
     4801 ttaaactttc ttgagtgcta tcagcagcag actttgttcc tttcatctca tcattgagat
     4861 gattgaatgc tgtcttagcc tgatttagct ctgcttccat cctgttggct tgtgtggagt
     4921 tctcaccaaa ttctttttta gtgatttcca attgctgttc tagatttgaa atctgtttac
     4981 ttacaatctc agactgagca ccaatctttt tctgagcaag agcatttctc tcggcttcac
     5041 tagcatttga acccaaagcg ctttcttgca gtttgaatga acttgtcacc ttactcatct
     5101 ctgaagcaag ttgactctgc tcattttgca actcttttaa ttggttcttg ttgttctgag
     5161 tagcactccc attctcatta agcgcctgat tcacatttgc aagcttaccc tcatatcctt
     5221 ttaggacgtt ttgagtcact tctacttcac gttggaaagc acggtactgg tcagcaccga
     5281 tatcgccatt tttgaattgc tgttccacct gagactgagc ttgtctcaag gtttctagtt
     5341 tctctttggt cgtcgaaact tgcttttgta agacctcttg tttctgagtc aggagcgtta
     5401 cgttccctgt atcaaatttc aaggccttgt caatctgtct caactcctga cttgcatcag
     5461 tagcggcctt attgacattt ttcagcgcct tctgcaaggg ttgcgtgtcg ccatcgattt
     5521 caattttgat acctttgata tttcctgcca tatttcctcc tttctcaaaa aatagaaaag
     5581 cgctgagaga acttctacca ctgataatgc agccagacca aggaacttgg tctcagaatc
     5641 gctctctcag cactcatttt tctttaaaaa ctgtcaaaat cagcttgcgt ggctttccgt
     5701 tcgccaccct tatcctcgct ccgtagattc acataatccg tctgataatc cagagccatt
     5761 ccgattgaaa tgtgctttag atcatcaata gaaagaccag tttctttaca gcaagataag
     5821 taggattcta ctgtgaagat ttcttcgcta gctgattctg attcatctgg tgcttttttg
     5881 tcgtcatgct cgcattcagc atttccatca atacaggccc aacttcctga atcggaaaga
     5941 cttccatttc catgaagaat tgttcataag gcttgatgtg aggatttgca gatttagcaa
     6001 agatccaaaa aagacggttg aaaaatgtca tatcaaaatc tgacagcatc gaaatgtcaa
     6061 tatcagttgc agtcaactct ttgtcagttt ccagcttgtt caattcattc atgaatgatt
     6121 gatttttcaa cattgaaaac aaatcttgaa aataatcttt cccaaattgt tgcttgtaag
     6181 caataggagt atagccgttg gtccccaact catactcctg atcaccaacc aaaacgattt
     6241 tacgcataga ttttctcctt aagctgcaac cgcagtaggt tcatagactt tcttgaacca
     6301 gttgtcatac gcatccttgt catcagctga tgtgatagaa cgcttgacaa ctgtatccaa
     6361 tggacgcggg ctagctttga aactaagttc acgttcgttg gttgatgtcc cgttcttagt
     6421 ttttgagcca agagatgggc gactggcaaa acagtagtac atcacatagc gagtcttgtt
     6481 tttgtcgcct tcaaactgga acatcattgc gaactctgtc aagctcgcat ctgctttttc
     6541 agtcataaca ccagtttgag ggtccttgat ttcaccaaga atttttgtcg caaattcatc
     6601 aatgatgtgt gggattttaa gtttaccctc atatccttcg tttgaattca tgaaatggta
     6661 atccttgttg tctgctttga taggggttgt ttccccttta gtatcaagta tcagctctat
     6721 tgctccagga aaacgaaaaa catcgccgta agtgataact ccatctgctg caagtgtctt
     6781 gataggtgcg atatgtacat tttctaggcc aaaggttact ttattttctt gagtcatgtc
     6841 attcctcctt agtatagata gactgtgtaa gacttgacat agagtctttc agtctcgata
     6901 aatgtttctt cttgaacttc aaaaaagagc ttgtggtttg cccacagctc ttccagacgt
     6961 tcttccaaat cttcatcctt actctcaaaa gccagctcaa ctgtcacgct cttaatctga
     7021 tgattaaccg tgttgtcagc tgaattgatg actggacttg attcataata gaccaggtaa
     7081 ggtaggtcag gagcgtttcc aattttaaac gctcgataag tgacaggcaa gtttgcctgt
     7141 tccaaaatag cagcaaagtc tgatagcttc atttcccaat ctccttgatt cgcttctcaa
     7201 agttctgaat tgctttttct tcagctggct tgatgtggac gataccagcg acacgaccac
     7261 catttcttga aaggtgcccg ttttcaagta tgtgagtaag acttgcaact gcgttgaaca
     7321 caacaaaaga gccattggcc aacttcttct ttttccaact tctacgatac tttccgtacc
     7381 gtttcggact tgtctctttc aactcatcca cagtctcatc agtcacttgc tctgcaatct
     7441 tatccacttc ttcagtaacc tcatcagagt aagctgcaag ctctttcgct atcaaatcag
     7501 caaggtcatt actcatttca acacctctga caaagtcaac tctaaaattt cagaatcaat
     7561 aggataggtt ttcaagatat gatattgctt gccttcgaac ttcgcaagct cttgattctc
     7621 atactcaaaa tttcgaatct caacgaccaa gctcggttta agccctacct gattcgcctg
     7681 ataaaattca gagcgagtga ccctcttttt gcgacataag agagtaactt caacatcttc
     7741 agagattggt tgtagtaact tatccttacc tgttactttc ttggagatca gtgtgatttc
     7801 atgattccac attcttgacc tctttctttg atgctatctg taaattatgc agtcgccact
     7861 gaaggtgacg tggcatatcc accccaccct cataacgata agcggcatag tcaacgataa
     7921 acatttcatg gtcagcacgc tcaccaacaa gctcgatacc gagattatcg gtcaattcag
     7981 tgatgacact tgaaatgatt ttttttaacg gcttgtctct caagtcggtt gaaataccca
     8041 acttaagctt cagcaactct aaaagctgac cttggtccat gtctattcct caacttcctc
     8101 agcagactct tcagcagttt cctcaactgt ttcttcctgc tcaactgcgg gctcttcctt
     8161 cacttctttt gtttcaggcg ctggtttctt aggttcatca tctcccaaaa cctcaaggaa
     8221 gatagagcca gcagtgttag cgccagtcaa aaggccattg gtaaagctat ctgttggctc
     8281 atatccctca cgaggaaaga tatcgccaac agcgtagtca tgattttcag gatcagccaa
     8341 gtccttgaaa ggacggatta ctttatagct catacgctac ctccttaagc tacaacatca
     8401 gtatatgttc cgaagaatcc agcttcttca tctgctttct taatatccaa acggataaaa
     8461 agcccaagca attgtccgta aatgtcattg ttcacccatt taacggatac ttgagaacgg
     8521 tcaaactctt tgacgaactc agtaacatct ccgatgaaga atttcatatc tccttcgttt
     8581 ccaaacactg tgtcatctac tttgtagatt gttttcccac caaatgaata gccagtaggt
     8641 gaagccacat cagtttgaag catgtagcgc ccatctttgt ccttcacttt gtcaagcgca
     8701 gcaaacattg acttagttac aacgatgctt gctttataaa ttgatttaag cttcttgttg
     8761 tagatatctt taataccatc aaatccagcc gcatctgctt gggtagctgt tttgaggaca
     8821 gctgtaacta atgacaattc agtgttttca ccttgattga acacttcgtc ttcaacaatg
     8881 gacatgatgt catagtctgc gtcgtcaatc atttcttgtg acacagggac atatccacgg
     8941 taagtcttga ttgaataatc aatctcgctg attgctggtt ttccgagttc tggatttgat
     9001 ttcaattcat ctgttgaaac cattacacca tccgttttct tgataactgg atatttacca
     9061 gatccactat taactttcac acgttccaca agatccaaaa gtggattacg tgttttatta
     9121 acaaaatgag gtttcaaaac ttcagtaggg attaaagctg cgcttcctga atcagtagtt
     9181 ttcaagccta caatgtcacg agtttgacca gtacgaatgt atttagcgat tgcgtcacgt
     9241 tgttccaatt tctgtcctcc acgtttttct tgacttgggt aagttggtgc tttacgattt
     9301 tgctctttga tttgtttatc taactcatcg atctcatttt caagctgtac tttttcagct
     9361 tctttttctt caatttccct ttgaagaccg tctacagtct tttcaactgc tgaaacttct
     9421 tcatcatttt tagcacgatc caacttttct aactcaacaa ccgaacgttt gttcaattct
     9481 tcgatagttt cttccaactc aactacctta gttgcttttg ctcgcatacg agcaccaaag
     9541 attaatgcct tattcatagc ttaaatttct ccttaatttc tttcttgcgc ttgtctagcg
     9601 cttcacgatt agcacgcttc tgactttcga agtctttttg tcgtgcagca atttccgttt
     9661 gtggataggc tgggaaagta catggactca cttcaaagat ttctagctct aagacagtgt
     9721 ccaaatatga accatcttca cgttcttccg tttcgatttt taccggtata aagccaaagc
     9781 tacaccctat aacatctcca cgcttgacac gggcataggc cccaacagct tgaggatcat
     9841 ccttgttaat gatgatatct ccaaaaagac caacatcatc aacacccagt gtcagagttc
     9901 cgttacctgt tcgaccgaga acaaggctat catcatggtt aaataaagct ctgatatcag
     9961 cgtctgtgac agctttctca acaccagcac gcttgattac ttcatgataa ccacgccaca
    10021 actccgtctc ttcatcaaat tttataaaat agccactcaa caccaagtct ccagattctt
    10081 cttctctcgt ttgaaattga gtggcacgat agctatttcg cttttgcatt ctcttcctca
    10141 cctcccttca gtttattttg atctcctagt ttctcctgag ggagaaagtt ttcaagaaca
    10201 atcaactctt ccatctcagg atcaggagcc atccctagcc aatccctcca ctcattacga
    10261 cgcattgcag cactgtttgc catttgttga gcaacagcag acaactccgt aatgttgtaa
    10321 gagaagagtg aacgaggatt tagcttgaag taacgattgc tagacaaaag taagtccctg
    10381 gttagtgttt gagtaatagt ggtagcaata ctcatgacag tcgtatttac aaagttgtta
    10441 tactctgtct tgttgaactc tcctacaccc aaaataaaag caggtactcc taatagacct
    10501 gcaactgttc ttttatccaa ttccacagac tcgtttaaag cgatgtccgt tagactaagc
    10561 ggttttacct gctgaatgtc cagcaatgcc tctggaacaa tccatggagc gccaaccctg
    10621 ctagtactca aatacttctc agcgatacgc tcacgccctt gctccgaatc tagttcagca
    10681 ctagacgagt ctactttaac gataagacta ggaatattct tcccgttcat aaagcttttt
    10741 ttagtcttgg tagccatgtt caaactttga accacatctg tcaacgtcac cctaaaacca
    10801 gtaccaatgt atggaatatc tggatctgga ttgatgacga agtggactac gtcatcaggg
    10861 gaatattctt cacccctaaa tgagattaca taggaatcct tatctgtttg gaatgaaacc
    10921 tctctcatcg gaaatggtct tagattagaa atataatccg taacaggttc atattccaca
    10981 tgtaggacag agttcccatc gccatataaa agcaaatcgc gcacaatctt gaaaatccat
    11041 gacttccttg tcatgtgttt acacggattg atatcaatct ttctagcaag cccatcacgg
    11101 attctgatat cacctttatc tgtattctcc atcaagtgga tggtcatatt agagaccaaa
    11161 tcagcaatct tattaaccgc tgtcaccaca tctggatttc tggccaaagg tacatacgag
    11221 tccatcaggt ttgacaaccc taaatctgaa tgactcagca tgttgattga cttacttggc
    11281 ttgtttcgtt tccaaaactt ttcaaaaata cccatgtttc ctcacctcct ttctaacgaa
    11341 aagtattttg aaaaagtgaa tcaaagtgtt tatttcttac gatattctga ctgacatcaa
    11401 ttacctgttt ttcccatttt actgtttcag ccatcaaatt tttcatatgt ctttgacgaa
    11461 tagttactac ttccccgttt aaaattactt taactcgccc tttgttgatc agcaagttaa
    11521 tttcatgttc tgataatact atttcattca taattcacct aatcaaagaa tctcatcaca
    11581 tcaccaccct tgccaagatt agcaagaacc tgtatacaag caaagacgct ggcatcaaac
    11641 aagtcaatcc ttgcagtccc accgtctcca tctaattttt catattgcac agcgtcatcc
    11701 accttttcaa ttgctctaac gttgctcaca cagtattcat aagcatcaga atgaagatag
    11761 taaaattcct tgttcttgac tttgaactca atccgtctga acccctcaga tttcagatag
    11821 aataactgag gctggtcaat catcttgaac ttagcctttt tcatcttagc taaaaactcg
    11881 cgaccaaact tcctatccat ccccacagct tggattttaa atccacgctc acgcatactg
    11941 atgaaccatt tgacgatatc gtcatagagt accgttggag tgttgctcat cgtcaaccaa
    12001 ccatcagact gccagccaaa aagtggaatc ccatcatcgt tagccttctt ctgagcatta
    12061 atccgaggaa agaaagcatg tgtgatacag atatcaacgt ctttctcacc atcattatag
    12121 acaccataga gagcagctgc tgttaagtcg tgcaatcttg acaagtccgc accaccatac
    12181 caacgaattg gcaagcgtgc cagctcttct agactccaat cgtaacaact atccgacgca
    12241 ataaactcat ccggattgaa ataagcgttc atagagtttg taaagatatt caaggtctta
    12301 ttgaaaaact catttcttgt ctgaggatca ttcatagcct gctctgcttc ttccttgaga
    12361 gccttgagcg aaaccgtgac cccccatgac ggattagcca tcttgaggat gttctcgtcc
    12421 agatagtcca ctacatcccc atcagcagat tgattagcct tgcagatgaa gatgaaaaat
    12481 gaatcatcag tgaccaattg cttgagcacc ttttgacagt atttcaaacg attagcaagg
    12541 aacccggtag gaatatcccc agctgtagag ataacaaaaa gcatactgtt acggtatgct
    12601 gacattgttt ttttcataag accatgtttc ttactgttcc tcattgtgtg agcttcgtcc
    12661 aagatgataa catttccgtt caaagagtcc agacggctct catcattcgc taaagcctgg
    12721 ataaagaaag aaccttcatc accaaaattg gcggtgatag agtgttcttg gttattatcc
    12781 ttgatacgaa tgttcttatc gttccagcgt tcaacgttga atcttaaaaa accaaaagct
    12841 tccatcgctt gcttgactga gttagcaacg atatagcatt tggaaccgct atctgtatct
    12901 aatatctgat aagcaagtgc gattgcagca gtaaacgagg tcttcccatt cttccgagca
    12961 agcatgataa gcgcttcttt gaacctgcgc tcattcgtac ccttgtagta aaaaccaaac
    13021 agattaacta caacgaaatg ttgccacggt tgcaaaagca atggcttgtt acggatagat
    13081 accgcaaaca tatcatcgcc ctgctgatga actatcacgt tctcgataaa gtgaataaca
    13141 aaatccacca tatcctcatc catctcaaag gttggatttt ctaaatcacg gaaaaaacgt
    13201 tcagcagcaa ggatgttttc ttcgcaatgt tcttctcggt gagttaagac gtgttgagcg
    13261 tattctttag ctttatcaag attacccatt gccaggcact cgcttcttct tgatttcgtt
    13321 cttgaacttc agtatctcag taagaactga ctcaccctct tgttctacta cctcaccgag
    13381 cgacttagga ttcatcatca actgattaga gtagctgaga atgtctttcc tcaaaatttc
    13441 catagctgtc aagattggaa ctttgcgctc attttcagca ccagccttat tgacgtaggt
    13501 gtctgttact ggataaccca agttagcata atcttgagca agtttctgat actggtataa
    13561 catacctgcg aaaatgtcaa tgatcatttc gaactctttc cgataagtgc ccaagtcttt
    13621 catctgcttg accacttttg acttaatcga ctttgctgta attggtttag ccaaaaacta
    13681 cctcctttcg tcaaaattgc ttagttttta cccccttttt gtttgaaggc ccccgacttg
    13741 gaaaaagttc ccttcaccgg taccctactg gccaaaatga tttttcaaaa agaggggggg
    13801 attaaaaatt ttcatttttc atttttgaaa aaatttaaaa attctttttt tctttttttc
    13861 tgccaataca atccttggtt gattactcta tcgttcactc tatcatgaaa cgtattatgt
    13921 ttcttattcg tcaatggcaa gcaattccat tcaacaaatt caagctcagg atattcagac
    13981 acaggaaaga tatgatgtac catttctgct tgaacagaaa ttccgtaacg caaactttct
    14041 tggcaaagat aatcatgctt acgcattatc ctatcacgga acttctccca cttcttagat
    14101 ttcaaggatg gtctgatagg tttgttatac atctcaaacc tcctttctca acgctaaaag
    14161 ggacaggcct ttgacctatc ccctcctcat acaagaaatc tatgctacca taataaacct
    14221 ttttttgtga gacttcaaga cgtcttttgt ctcattctga ttctttaaaa aaattacccc
    14281 gttttactag tatggctgtt agcggtatgt gcattccatt tacaaatgct gtttgagtat
    14341 atccaacaat ttcaaagcca acttcaggat tggcatcaat atctttattt aatttctcga
    14401 aggccttttc tccaagaaaa tcatcacgat attcttttat cattttctac ctcctgtaac
    14461 tataccaatt ttacccatca ctttcacata tcttatattt tgttaaactc actctaaatc
    14521 tcaaaccctt actaagcatg ggttttaaag agtttcattt tttcagttta tgcttaactc
    14581 attatgtgaa agtaatatct aaaaaaatta aatgacaaag ttccgtaaag catcatcgag
    14641 ctctgcttgt tctatcccta tgtatctcag ggtaattgca ggtgatgagt gattgaacat
    14701 tttctgtaat gtccctacgt cctttgtctt gttgtaatat ttatagccga atgtcttgcg
    14761 cattgtatgt gtgccaacat tatcaatgcc aagttcttca gctgcttcat gtatgatttg
    14821 ataggctcgc tcacgagtga ttgctttatt ctgaccttgc ctactcttga ataagaaatg
    14881 atgaaatggt ttgccctcga catatctcct catttctttc ttgagttctt ttgtcatccg
    14941 tcttgttatc tgcttgccag tcttccgttc tctcagtttg atgtgccagc cttgaacatc
    15001 tttaactttc aaggtaagta tatctccgac tcgcaaacca gtattcaggc ctgtaatgaa
    15061 tagcatataa tacatctcat tccactctct aagataatct ttcattgcct gaatgtcgtc
    15121 attatctttt atcggtgata caaattccat attctacctc ctttccaaaa acaaaaagcc
    15181 agcatttgct gactcttgac gatacttctg ttggacaact ttttgactag aattaaggat
    15241 gactcctcaa gtgtgatgtg tgtttttgtt tcagaagttc atgctatcat aatagacctt
    15301 tttttgtgag acttcaagat gtcttttgtc tcaatcttat ttacaactca cctttcagta
    15361 tagcgtactg ttctaagata atccttctac gtcgatagat tgtagctttg ctcatgaatt
    15421 tctgttctgc tatttcttcc catctcagtt gaggatatct ccagcgcaga ttaaagattt
    15481 ccttatcttc atcaactaga ttgatcaaga gtttgttaat aatagctttg aacccttcga
    15541 gaaattttaa ggttggatca tctgcgattc tgactgcgat agtttcggta ggtttgctta
    15601 ttcctacgct gggaccactc tgagcatctg ggtttcgagt ttctaattct agccttctca
    15661 aatctattgt acgttgaatg ttttgaaatt tgaaaagttc tctgtctaat gttttgaggt
    15721 cttcgtcgct caattttttc aatttccacc tccaagtttt tcaaaaatgt aaacaagtta
    15781 tcaaaattgt cgagatcgga tatctattcc tacttgtctt cgttccataa aatctaactg
    15841 tttgttcagt aataccaaac ataggatttt aaaatatctc actcgttgac ctccaaaagc
    15901 tccggatttt cgtagacatt gccgatgatt tcctcatatt ccgtccacgc atatccatct
    15961 ccaaatcctt ttaggtatac agcaggcatt ccacctatgt atgtgccacc gtattctttt
    16021 tctaaatata cttcatggag acatcctctt gtacatttaa cgatgtcacc gatgaatacc
    16081 tccttgccgt tcttgtcctt gagtcctgtt gattgcatga tacattcata atcatcaaaa
    16141 tgtaaccaat ctttttcctc ttcgatccaa atgataggac aagtccagtt ttcgtcatct
    16201 gtatcacaat tgcctaccat gactttgtag ttcatttcgt ttcgcgctct atcccacact
    16261 ctaaatttcg gtatcatgcc aaatcctcct ctttgacgaa agtaccgtca atccaacgac
    16321 cttttcggtc tttgatttct tggtatgcca gttcaaaaca ttcctcgaag ttataaccaa
    16381 gggcgatact taacgatttt aaccagtaga ttgtacgtga cagatataat tcaagaatgc
    16441 cattgtcacc aaaatcttga cataactgaa attcgcttat attttgattt aaaaaaacaa
    16501 aacatgtcat tacatctcta tcatttcctg atgttttaaa aatcttatgc acatcctttt
    16561 ttatcagcaa ggccagaccg acaatcacga ctgcgcaatc tccgatgctg tcttttgtca
    16621 gttgctcatt cttcttgaga tagcctgcgc ataactcacc gaactcttcg ctaagtttta
    16681 atgactgctt atccagtcgt ccaccgtttt ctaaatcacg gtcaacaaac cactgttgaa
    16741 ccttttcttc caaattcatt tttgtattca tcttattttt cctccgtttt tctatttttt
    16801 tataacaatt ccagaaatca tctagatttt tagaaattgg catttcccca taggttatat
    16861 aacactgaat agcttcttct aaattattgc tattatcagc ttcaaaatga acaagttcaa
    16921 aatcattttc gtcaaaaatt tcattcaatc ttcgttcaat taatagttga ctagcacgag
    16981 cttctttcaa ttttttatga attcagactt tgtcaacatt ttcatttcct taatacctcc
    17041 taaaatttca taaaagccat ccagtgagtt gtcccacgtt gctgaccgaa aagcggttga
    17101 tgcggaacca attccaaaat ttctttaaca tttacttgag catcagacca cttgaaaata
    17161 agtgttcccc ctgatttcaa gaccctaaaa cattcttcaa aaccttgttg taaatctaac
    17221 ctccaagtca gtaaatctaa ttgtccatat tgagcacgca tgaatgattt ctggccagcc
    17281 catagaagat gaggtgggtc gaacacaaca agattaaata tttcatcatc gaatggcatg
    17341 tcacgaaaat caccgataat atcagggtct acattgacct ttttgtcatg tatctcaaat
    17401 gtttcttgcc taatatccat aaaaattgtg tgactttcgt ttttatcaaa ccaaaacata
    17461 cgactgccac aacaagcgtc tagtattcgt atatctccca ttattccacc tcctcaaaat
    17521 aactatgaaa tttacttaaa ttgacaatag cgacctcttc aacagaatgc tttccgatgt
    17581 caaagtctgg atcattcttc ccaaattctt tttctatagc tttttcagcc agaaaaggca
    17641 aatcgaatat acttgcccca tttcttaaag cgagcgcttg accgtatttg ttcactattc
    17701 gataccctat atcaaacggt ctgatttccc ttgggacttt tatgcattta ctttgattct
    17761 tcattccttc ttcaagtgtt tgtgtcatca ctccacctcc tcaatctcaa acccttcaca
    17821 atcaaacacc cagccgattt ttgcattttc tagttcttta cgggtgtggg aatatatagc
    17881 atcgtctaaa ctaaagcttt ttgtaaagaa gtacctttcc aaaagttctc cataaaccaa
    17941 catattttct ttaatattcc ctttaatctt taccagatac cgcttctctt tttcgacctc
    18001 atagccgtta agccaagcaa gacagaattt ttcgatgtta ttttcgtaaa accaatcagg
    18061 aactttctta tcataatgat cttcaattac tctcattgca ccgtaaacat gaaaattgtt
    18121 tttcttttta aattctatat attccgccac acactgcgga actttgactg gttttggttt
    18181 atctagttgt tccaagtctt gcagaaaaat ttgacgagct agttctgctc cttcagcatt
    18241 ccatacaccc tcaagttttt tatatttctt aatcaattca ttaagtttca tcttcgcttc
    18301 ctctgtaaat caaataaact gcaataacta cctgagccat gcttggcgaa tagccaatcc
    18361 aatcatcaaa ctccttagat tttggcaacc aatccttagt agatcccaaa tcatagtctg
    18421 taggcttttc atcagcgaag atgcattcca tcgctcccat aaacgtcata ccatcttctg
    18481 ccatttccca aaaatagtcc gcccggtctt tcaccgcttg tggtaaatct tgcttgggag
    18541 gttgcggctt cccgtcttct accgtccagt tgtatacttc attaactttt tgctttaact
    18601 cttccatcat cttccaactc ctccgctttc cgtcttaatt ctttattctt tttcctcaac
    18661 aaatcgcgct ccagcgctct aatccgtctc ttgcgtgcat cgcacggctt cgaatactcg
    18721 attatcttct cttcgttttg ctcgattgtg cgtttcagtc catcaatgac tgttcgttta
    18781 tcataattca tcttctaaaa atctttcaat agcttctctg taggagactt ccaccagacc
    18841 gtctaagtcg ttcagggctt caatatagtc tggacgacct tgcccgtact gctctttcaa
    18901 aaattcaaca aagagatgaa tttcctgata ggttactcca accatgtttc ttacctccca
    18961 ctaaaacaga atagccattc caaattcttt aataagttca atcattttct tctcctcctg
    19021 aaaaagtcgc taaatagtaa caatccttag aaccgtagtc aaaccgtgtc gtccgctgac
    19081 caatgtgctt ctgaaacctt ggatgagtga tagccgagaa cacccattga tggtcctcca
    19141 tctgctcaat gagatcatcg acattgtcaa acctcccaag gaaaaacttg cagtgcccat
    19201 tgtagacgaa gtaaagttct aacatcactc cacctcaatt gggtaaaagt tcccaaagga
    19261 acccctcaat gccttaccaa cctgtacggc tgccccacga gaaacaaacc gcatggcttt
    19321 cttctcctca gaacatgaaa tgtccaagcc agtcacaccg ataacagcgg acatcagaaa
    19381 cggcttatcc tctcgtgtcc catgctttaa aataaacatc agccacctcc gttctaaaaa
    19441 tattgcttcc gcttgtttgt caagtcgttg aaaaccatca aatggtcttt atccaccccc
    19501 ttcatcagtc tggacataaa gggtctgcca tatcttttct gaatatcagc agaagtcaaa
    19561 ttggtggtaa tgattgtatt tgaacgctta ttcaggatat tgtagagaat agtaaacgac
    19621 cattcgctat ccttctccat gcccaaatca tccaaaacca agaacttagc gctagcaatc
    19681 ttattgacca gaaactcttc ctgactaaaa tcagctttaa tcttcatcag taagtccgtc
    19741 acattgataa atatagcaat ctctttcgtg tactcagata aagcctttac catagcaaag
    19801 gccaaatggc tcttgccagt tccagcttct ccttgtagca cgatgttgtt cctagcaccc
    19861 tcagaccact cacgacaaat cctctttgca aaagctagct tttccgcttc tttttcggtt
    19921 ggcgtctcaa aattgtccaa agtcgcattt ttcaaaacct catcataaag agagaacttt
    19981 tcaagatagt atttcctctc tcgctcattc tcagcattag ccagttcatt cactctttcc
    20041 tgattttctt catgaatccg ctcagattca cacatgcgac atacaacact ctcggtcctc
    20101 aatatcttta tcaaagggat gttatgcttt tcgcagaact cttcttgttg ttctgtattc
    20161 ctacgataag ataaggcgat ttcctcaaac acattgtcta ccatactagc cgacctccgc
    20221 attcatgcca gctagccatt tcagacaagc aggcaaccac ttgatgaatt ggttggtctg
    20281 ctaaaagagt tttcttctcg tagcttaacg gataatagtc aatctcgaat tgttcaatta
    20341 gttctagtac ccccattcgt ccttggcctc ctgttcttct ttcttatcct tgttcttctt
    20401 ttccgattga cgaacctgtt caacagtggt aacattgttc atctgccaat ttcttaaaat
    20461 cccaccaata tatttgatgt tcggctttcc tgagttaata gcagtcttca atgcttcttt
    20521 caccaaatcc acatcattct catttagtag atggttgatt tcttcaattt caaatccaga
    20581 taagagtcta cgaaactcag attgaaaaag ttctaagata ttttcttcac taccactact
    20641 agtagtagtt attcttttct tattcttatc tttatctaat ctattcttat tcttatcttt
    20701 atcttcttct agtgcgttac cgtccgttac tgtaacgtta cctgtaacgt taccaagagc
    20761 aagatttttc tgttttttac ggtatttggc tacacggtta cgtgtctgtt ccttgatttt
    20821 ctccattccg tcaacgtttt gatgtttttc ccaatttggc aagctaataa taccatcgat
    20881 aatctcaatc atcccaaact gttcaaaaac tccaatagcc attcttactg tattcaatgg
    20941 tctacgaaaa atagtagcta acatttcatc tgtatagtga accttatcag tcatcatcaa
    21001 caaaccatta ctgttatgtt ttccagcaag tgtcaaaatc ttgaaccata tcactaagat
    21061 ggcatcagga tcaggcaagg catcaatcag gcaaatcttt tcatcgtcaa aaatatcggt
    21121 tgtgattttt atccacttaa tttcagacat acctagcacc ccacttccta cggttagcgc
    21181 gatacttcat ccgcatatct tcatagatgt acctgccttc cagctccatt ttttcaatct
    21241 ttagcagctt atttttaagg gtcacataac gatagtcctt tgctagtttt tcatagtcgg
    21301 ttaggtattc tttgactagt aatagatttt tataatcgtt ttcccatatc gtaataaaat
    21361 gtcttgaagt tgattccctt ccttccagtt ctttaacaat cataatcagg ttatccagcc
    21421 attcaatcaa ttcttccatt tcctgacctc ctcattacaa aaatctgatt gcagactgtt
    21481 taggttctgg caaagctaac ggctcaggac gcaagcctac aggcggttca ttgtcgtagg
    21541 taaagccctt gaacggacga cgaatattct tgcggatttc ttgacgttca gcctctctac
    21601 cacgttcgta agcatggtta tagcctcgaa taatcataga cgcaaattct tgctcttctc
    21661 gtctttcttc ttccttgcgt tgttcctgca atttgatatg acggcaagcc cctgcaaatc
    21721 caagcagtaa ggctccaacc cccatcagct ggtctaaaat cggtggttca aacattttta
    21781 tctccttatc ctctttttgt gctataatat agtcaaataa ttttgctaag accttgtcca
    21841 gaagcctttt agtaaagtta ttatatttga ttagagagcc attctttgat ggctcttttt
    21901 gaccatttct taccaggtaa ttcctttgga aatcccttta agtaacgata attatctgaa
    21961 aatgtggcat acttaattcc tagaaaatca caggtagtgt tcacatccat cagctctgga
    22021 tagtggtcac tatctttttc tatttcgact agccttgtga ttgtgtcctt gataatggat
    22081 ttaatccatt cagacagtga aagtagaaca ttgtccatct tcttcccctc ctacccttcg
    22141 tcaaatgagt tcaattccat gattttcatc ttggtattgg tgcttggctc ccaagtcatc
    22201 caataggcca aggctgcatc tgcgaatttt ttcggtagca agtcatagcg attaatgttg
    22261 aagtggtctt taaagtcaat ctcagcttgt ctaaagactg actgagcgaa agtcttatcc
    22321 gcataagccg gactatcaat gccacctaag caagccacga cccgagcctt acgcttcttc
    22381 aggagcgatt tagcatagct tgggtgaatc ggttgctcac tcttgaggta gtcaatatct
    22441 tccagcatag tcgcttgttg ctcacgcaac ttcttctgtc cagtaaacag agcgatgaaa
    22501 gcatcttcat ccaagtcctc tcggataaat ccgccttgtt ttctaatagc tggcaagacc
    22561 tctgatgtca cccaacgctt gaactctttt gcttgaagca atttgctgga taaaatgaga
    22621 gagtagagac cagattcatt gatgatcaac atatcctgtg ttccaccact agtagggatg
    22681 ccctgtttta gggcgtcctc ttcatcaaca tgaagagcaa tcgcatttct agccttacta
    22741 tatcctagga tgtctgcgac atctttcccg acgaaccaag gctcgttatc aattgtcaaa
    22801 gtacggactt cctgtccgtg aaaattaaaa atttcgttca taaagttcct ttctaaattt
    22861 ggtataatta aaataaaacg attggagaaa tcttatggaa tatcaagctc ttattcaacc
    22921 tgtgattagt attattcttg caataatatc agggttatgg tcatatgtcg catcaaaagc
    22981 taacaataaa gctgagattg aaaaacaagc caaagaacat tcacatactg ttgaaaaact
    23041 cgaaagagaa tttcatcatc agatagatac tctaaaacag caacatgcct ttgaacttga
    23101 aaaaatcaaa caagctcatg aattacggtt gcaagaactt gagaaggtat ctcagcttga
    23161 tactgaaacc gacaagtcta tgaagatgaa tgatcttacc tacaaagttt ttacaggcga
    23221 ggttgatttt gacaaagctt taaaaatagc taataaagca agcaatagca aacaaaactt
    23281 aaataaaaga tttattcaaa agacttctaa aaaatcataa attaaattta tttctaactc
    23341 tttcaagctc atcatcttgt atttttttaa acccgttgat gcgcttttct ctatctcttt
    23401 tgctagcgta gtatgtagca aaaccaatga taagattgat tatgacaaca aagtaaaacc
    23461 atactagttc attcatctcc accctcctac tccagcacct tactgccgac taccaatcgt
    23521 ttaacgacaa cgtccatctc cttaaattcg gcattctctg cacagtagcg gacgctctca
    23581 ctgatgatgt gacaaataga taccccgtac tcgttcgcca actccgtagc aatctcccag
    23641 gcatctttgt caatccgtgt tactttttgc gctgcgttgt tcatactatt tcctcatgct
    23701 ctaactattt tcccaagggt tttcaatacc caaaatatct acgacttttt ctttcacata
    23761 atcacttcct tttccatact tcagcagttc tgaaataact gatgatgtta cagatacttg
    23821 ttttgccaat tcggcttgag tcatatccag ctcaatcaaa cgagttttga ttttagcctt
    23881 gattatcttt agttctttac tcatattttt cctttctaaa tttgatataa ttaaaataaa
    23941 aacgattgga ggagaataat gaaatcttca ttttttcact atctaaagga aatcatctta
    24001 tatggtgtcc tagttccgat tttgacagtt atcgtaggat ttcacctttt tactaccttc
    24061 tatcctattt ctgattcact gttaacagat ttcttgaaag cttttacaga acaaagaatc
    24121 cttgctattg tattcgttct tattctttgc tttatatttt tcggttcaat ttattactgt
    24181 atttcatgtg gacgaaatag aaaattgata cctgataaag tttatacaca aatcacaact
    24241 tacatttcat ctgtaggttt agggactgca gtgatagctg tcgctacctt gactctcaca
    24301 gaattacagt tttcaatcct tacaggttgg attgctttta tcgctttgtt gttgccactt
    24361 ctgaagttta aagtccaata cagcacctat caaagtagcg acaatgtagc acagaaaact
    24421 accgaaaaca aagccaatta agaaaggctc taccattctc ctctccccct ttcttttaaa
    24481 aaattatcta aaaagttagc gaacttcttg acaactctag tcaaatgttt taaaataaaa
    24541 acatagagaa aagacctact aaaagtaagt tttacctaca gtaaacggac gccaatcagt
    24601 tttgtaaggc tttatttttt agttgtctag ttcgctaact ctttagctta cgaatattat
    24661 tttaaaacat ttgactaaat aagtcaacta ttttctacaa atattttaaa attatttttc
    24721 gtttgcttag aaaggttgaa aaattaatgt ttgtagcatt cgataaaata aaagaattag
    24781 ctgataaaca ggggatttct ataaatattt tagaagaaaa acttggttat ggaactaata
    24841 ctttatatcg attaaaaaga agtaatccta gttcaaaagt tttaaaagaa atagctgatt
    24901 attttaatgt aagtgctgac tacctactcg gacggacaga taatcctgct atcgctggaa
    24961 gtgatgaatt tgctcaagta aatggacaaa tcatagactt acgcaaagca gcagccaaca
    25021 ccatgttatt tgacggaaaa ccactaaatg aagatgatat cgacttcatc acatccgttc
    25081 tatccgccca cttcaaaagc aaaggagaac gctaatgact atcacgatca atttcacaga
    25141 aaaaaactcc tacatcacgg actacctaac caaacacggt atcgacacaa caaccatgga
    25201 ttttgacgac ttcatggtac tcatggaaga tatcgaagac gcacgagcag ccgaccaagc
    25261 ctatatggag tatttagccg acccagctac ttataccatg gatgaggtct tggatgaact
    25321 aggactatct cgagaggata ttgcttaatg tatcggctag atattgataa aaaagctctc
    25381 aagcaactta aaaaactaga taccccaacc agaaaacaaa tcctatcctg gcttgctaaa
    25441 aacattgaaa acacgaccaa tccacgacaa cacggaaaag cactaaaagc caaccttgca
    25501 ggttactggc gatacagagt agagaattac cgcatcatct gtgatatcca agacgataaa
    25561 ctagtcgtcc tagccgtgga aatcgcccac cgcagagatg tttataaata acgaaggaga
    25621 actatgacac tcgctaaact ctgcgaagaa tatcaagtag agctttgtct cttcgacggt
    25681 tcaaactggc acagtagcgg tttctacaat ccagacacaa acgtactcgc tattgaccac
    25741 aacttagctc ctgaacaaca aatccaagtc gccctacacg aactcggaca caaagaccat
    25801 acacgctcag agtaccaaaa cgctcgccta cgctgtgaaa acgaagctga taggaatatg
    25861 atccatcatc tcgtgaaaga cgcactagaa agcttagacg accccacaga gtttgattac
    25921 ctcaaattca tgtcttacta caatctaaaa actatgacta atgaagtcat ggtcaaggaa
    25981 gagtacttgg cattagtaaa ttaaaaattg cattgaagat atttatatag aggggaaata
    26041 tatgcaaaag actgttgaaa aaatattatt cagagtcgct ggagtgacaa aatataaaaa
    26101 agcagtaaaa gaagcttgca atatgattgc tgaagataac ggaatcccag aatatgcaaa
    26161 gtactatagc aatttatcaa ctaaggaact tagagaagaa cttgaagaat atggtctgaa
    26221 agttttcaaa tatcaagatt tagacttttt caatattgag ctcgttccag aagtagataa
    26281 tagatatgat cctaatgcta taaaagtttt gatatttgat aatcatgtag gatatgttcc
    26341 tgcaaccatt gctaaaacaa tacgaaaata ttttgataat aaaaaatata actttgtaat
    26401 agagggagag ataaaaggtg gcccatataa agaatgggac gagtatgaag aaaaagttgt
    26461 cacaaataat gatttggatg ttggttttga aatttacctt accattgttg attcttcaca
    26521 aaaagaagta attcagagcg aatcatctga gataattgat gataacattt ccaataaaga
    26581 agttacggaa actgaagcta ttgaaactga agctattgaa actaaaacaa ctgaaactga
    26641 acatattgaa caaaatattg ttagtgacag tgtcgctgat atagtaaacg agattaatct
    26701 ttcagaaaca tctcctaaga aaaaacttcc tgccaataaa atcatatttt cagcactgta
    26761 tcttttctta gtcttttttg gagttgttgg tattccaatc gctccattcc ttgcagtccc
    26821 tttgacagct tggagtttgt ataaactata caaactattc agaaaataaa aaaaaagccc
    26881 cacaatcgcc ctcgccaaag tttgattgtg aagcttaccc ttataaaaaa tcagccatta
    26941 aaaaggcctc ttttctatac cctattttac accatgaaag gggtgatgtc aatattctca
    27001 atgtttagac cttgtccaga agccgataaa caaggagaat acaatgaaat ataataaaac
    27061 aaaataccca aatatctatt actatgagac tgctaaaggc aagcgttact atgtcagacg
    27121 ttcttttttc ttccgaggta aaaaaagaga aaaaagtaaa agtggtttca caactctccc
    27181 tcaagctcgt gcagccttgg tagagcttga gcaacaaatc caagaacaag aattaggtat
    27241 caatacgaat ctaacgcttg atcaatattg ggatatctat tccgaaaaga gattgtcaac
    27301 agggcgctgg aatgacactt cctactacct caatgacaat ctctataaga accatatcaa
    27361 ggcaaagttt ggttctatcc tgcttaaaaa tttggataga aatgagtatg aactatttat
    27421 cgctgaaaag ttgcagaacc ataccagata cactgttcaa accctcaatt ccagcttcat
    27481 ggcattgctg aatgatgccg tgaaaaatgg taatctgctc tcaaatcgct tgaaaggtgt
    27541 tttcatcggc cagagtgata tccctgctgc aaacaagaaa gtgactctca aagagttcaa
    27601 gacttggata gcaaaggcag aagagattat gccaaaacaa ttctacgctc tgacctatct
    27661 gacaattttt ggattgagaa gaggagaagt ctttggattg cgtccaatgg acatcactca
    27721 gaacgacagc ggacgggcta tactgcatct tagagacagt cgaagcaacc agaccttaaa
    27781 agggaaagga gggcttaaaa cgaaggattc agagcgatat gtctgccttg atgatatcgg
    27841 aacagacctg atctattatc tgatagctga agcttctaag attaagcgaa agttaggaat
    27901 tatcaaggaa cagcacaagg attatataac tatcaacgag aaaggtggtc tcatcaatcc
    27961 aaatcagcta aatagaaact tcaatctagt gaatgaagca acaggattgc atgtaacacc
    28021 tcacatgatg cgccacttct tcacgactca aagcattatt gcaggggttc cgcttgaaca
    28081 attaagccag gcgctggggc atacaaaggt ttatatgacg gatcgttaca atcaagtaga
    28141 ggacgaactt gctgaagcga ccacagacct atttcttagt catattcgct aaaaaaagtc
    28201 cccgccaatt ccccgaccaa aaaccgaaaa ataccgaaaa atatcgaaaa attattttta
    28261 gaatagtccc caaaagcctg aaatagagct aaaaaactcc acctgattcg gtggagttaa
    28321 gggagattat tatgaaaaag aaaagtttag gattttatta aataaagtta ggaggtcttt
    28381 atttaataac tacatgatac aagacgaaac ttaaaactag cttaactttt ctaaaatttt
    28441 actattttgc aaaaaatttc tatcaccagc acctcaccac gcaaaaaagc cacctgattg
    28501 ggtggcttca ttaggagatt gtgatgaaaa aagtttagga ttttattaaa taaagttagg
    28561 aggtctttat ttaatgatta tataatacta gaccatcctt aaattttgct taagaaaaaa
    28621 caagttttgt tatttttctc gattcgccca agtcatccct atacaattat aggtggataa
    28681 gatttcaaag cccatagaac gataaaatcc cacgtttttt tctgtctctt ctgtcaccag
    28741 ctggacttga taggcatctt tgtaatcctc taaagcctct ttcatcaagg cactaccaat
    28801 tccttgacgc tgatagattg gtaaaacgat taaatcctga accaatactg atgagaatcc
    28861 atctccaacc aaacgaatca agcccaccac agcatcacca tcaagtgcca gataaattac
    28921 taatgaatga gataaggcct gctccagcat ctctggttga tgggtataat ttgtccaacc
    28981 gacagcctga tagagatgta aaacatcctc tagcttgaca atttcttgct ttttaatagt
    29041 aatcatgtca acacctctta aaattctctc aagctcttgt actgctgtcc atttttatca
    29101 aaattttcag gacgcaacca tgtttccaaa cgatctttga cttgaggcca gtccttatca
    29161 atcatagaca accaatccgt atctctcgta cgtcccactg cctgacggaa ggttccttca
    29221 taaataaagc tcaaacgctc cgcagctcgt ctggatggca gatttaagca tcgcatttcc
    29281 actcgtagcg acgatagttt agctcctcaa aaacatagcg agctaggaga tactgagctt
    29341 cagttcctat ccgtgtaccc cttagctctg gagaaaaagt gactgctccg acttctatta
    29401 ctcggttatt ctggtcaatg cgcatgagag aaaaagatcc caaagcctta ccagtcgcct
    29461 tgtctatgat tgcatagtaa aaacggtcct tacgagccaa catctgatgt aaaaggctaa
    29521 ccagctcccc catatctgct actggctact gaaaaaggta ggtccacatc tcctgaggcg
    29581 tatcaggccc ataaacagct agcaaatcct ccgcatgctt ttccactgaa agagcctcta
    29641 tcctagcata acgcccttct aagaaatcaa tagaaggcag ttcacctggt gtataacctt
    29701 ccattgactc cccaatcatt tgaccatatt catttactgg catagctttc tccttttttc
    29761 acttttcaaa ctttatagtt gcccatagta taccatactt tcataagaag attcaaaaaa
    29821 tcctccagat tctactctga aggattccta ccttatttca caacgatatt aacgagttta
    29881 gttggctcaa acagtttggg aaactgtttg aggttggaaa tcagcaaata aattggttat
    29941 tttacaacaa tattaaccaa tttatttggt acactaatca ctttcacgat ttccttaccg
    30001 tcaatttctg ctttgacttt ttcatccgct agagcaattt cttgcaattc ttcacgtgat
    30061 aggtctttag cgaccatgag tttggcacgg actttacctt tgatttggac aacgatttcg
    30121 atttcgtctt caaccagttt actttcgtcc caagttggcc aagctacata agagattgac
    30181 tcacctgttt ctgcgactgt ttgccagagt tcttctgcca agtgaggtgc aaatggtgca
    30241 atcaattgaa taaagccttt ggcatagtca acataaagct tatcttcctt gttagcagca
    30301 ttgacaaaga ccataagttg ggcaatagct gtgttgaatt tgagagactc aatttgctca
    30361 gtaacagctt tgactgtttc gttgtaagcc ttgtcaagag caccattgtt ttccgcaagg
    30421 atttctttac ttgtaatcaa acggtaaact cggtcaagga acttacggct tccttccaaa
    30481 ccttcttctg accaagcaat cgaagcatcg agtggtccca taaacatttc ataaacacga
    30541 agggtatcgg caccgtattg ttccaccaca tcatctgggt taacaacgtt cttgagcgat
    30601 ttagacatct tggctggcgc ttgctccaac tcttcccctg tttctatatg aaagaaggaa
    30661 ccatcacgtt tttcaacctt gtcggttgcc acaagagcac cacggtggtc acggtagctt
    30721 gttcccaaaa tcatcccttg gttaaagagt ttttggaatg gttccttagt cggaacaaca
    30781 ccgaggtcat agaggaattt atgccagaaa cgagcataaa gcaagtgaag tacagcatgt
    30841 tccgcaccac ccacgtagat atctactggc aaccattgtt tgaggaggtc ctcatcagcc
    30901 aatttctcag tattgtgcgg gtcaatatag cggaggtagt accagcttga accagcccat
    30961 tgtggcatgg tgttagtttc acgacgacct ttgacaccat cttcacgagt cacttcaagc
    31021 caatctgtca agttagctag tggactttca ccagtacctg aaggacggat atccttggtt
    31081 acaggcaaga caagcggcaa ttcagtttca ggaacagctg ttgaagttcc atcttcccaa
    31141 tgaatgattg gaattggctc accccagtaa cgttgacggc taaagagcca gtcgcggagg
    31201 cggtaggtaa ccttctcctg accacagcct ttttcttcca agcaagccac aatcttggca
    31261 atagcgtctt ctttgttcaa tccatctagg aagtctgaat tgacatgcag gccatcctct
    31321 gtgtaggcag cttcttcgac atttccacct tcaagtactt cgacgattgg aaggtcaaat
    31381 tgtttggcaa attcccagtc acgttggtcg tgggcaggca cagccataac cgcacctgtt
    31441 ccataactag caagaacata gtccgcaatc cagattggca tttccttacc attgacaggg
    31501 ttgatggcat aggcacctgt ccaaacacca gttttttcct tagcaaggtc tgtacgaacc
    31561 aagtcagact taaggctggc ttggtgttta tagtctgcta cagcttctgc ttgctctgaa
    31621 cttgtgatag cgtctactaa ttcatgttca ggagccaaga cagtgaaagt cgcaccgaaa
    31681 agtgtgtccg gacgagtagt aaagactgta aattccttgt ctgttccttt tactttgaaa
    31741 gttacattgg caccagttga tttaccaatc cagttgcgtt gcatatcctt gatagactct
    31801 gaccaatcta gttcatctaa gtcattgagc aagcgctctg cgtaagccgt gattttgagc
    31861 atccattggc gcattggttt gcggacaact ggatagcctc cacgctcaga agttccgtca
    31921 ggaagcactt cttcattggc aatggcagtt cccaattcct caacccagtt tactggcact
    31981 tcagcttcat aggccaagcc tttttcgtaa agcttggtga aaatccattg agtccacttg
    32041 tagtagtttg gatctgttgt gttgacttca cgatcccagt cataagaaaa tccaagcgca
    32101 ttgatttgac gtttgaagtt ggcaatgttt tccgctgtaa attctgctgg gtcattacca
    32161 gtatccatag cgtattgctc tgcaggcaaa ccaaaagcat cccaacccat tgggtgaaga
    32221 acattgtagc cttgcgcacg tttgtaacga ctgaggatat cggttgcagt ataaccttct
    32281 gggtgtccta cgtgcagacc agctccagac ggataaggga acatatcaag cgcataaaac
    32341 ttaggttttg atgcatctgt tcctgtctta aatgtatgat gttctgccca gtagccctgc
    32401 cacttaggct caatttcttt atgattataa aaactcatgg tctctctcca attttgtgat
    32461 gttactatta taccattttt gagggaattt gaaatgtgtt taaaggaaaa actgtatact
    32521 gtatctcatt aattttgatg actatgaatt gctctatctc ccacttttta tcccattgtt
    32581 atgcagtaaa tcaaggagta agtcaagaag cttatctcgt atagcacaaa atacttattt
    32641 tagaccgaag ataaaactgg aatgctaatt aatgtattca caataaatag ccgacaacct
    32701 atgtcgcttt ttgatttatg aagaacgtat agtgcactga atctgaaata gtacgaaaca
    32761 attgctaaaa cattgttaga aattaatttt actttcccaa tcgatttgtt ctcatcttat
    32821 ttcaatctgc tatagaattc aatacgagga tcaataaaag actaccattt ggaaaacagt
    32881 agtccttatt gtttattttg aatttacata ggcatctaca gcgataatag cttgagcaac
    32941 atctgaaggc gaaatcttaa acggcatctg atgaattgtc tcaccctcca tagttgcttg
    33001 tttaccaact tttattaaat catcatatcc aacttgatcc aaatgcattt cttttagagt
    33061 tgttggcata ccaatttttt tgtaaaactc aatatactta tcaagttctt ctttaggtct
    33121 attttccaat aatagttgta ctaaagttcc ataagctact ttttcaccat gtgttaaatg
    33181 atgaatgtca cctgtcaatg cagtaaaacc attatgaatt gcatgcgccg cagctaatcc
    33241 tccactttca aaacctagac cactcaataa agtattagct tcaacaatat tttctaatgc
    33301 tggtgtcacc actttagctt cacaagctgc catagcctgt aaaccatctg caaacagcgt
    33361 ttcttcacat ttcttcgcaa ttgcaactcc agccaatgtt tgctgttgtc ccaacatagt
    33421 ttttccattt gcctgcataa ccgcacgcgc ctcaacccaa gttgctaaac catctgcaat
    33481 accagacgct aataaacgct taggggcttg tgaaataact tttgtatcaa ccaaaactaa
    33541 atctggattt ttagaataaa atagataatg atcaaatgca ccttcatctg tataaataac
    33601 agataaagca gatacaggtg cgtcggtcga tgcaattgtt ggagcaataa taacaggttt
    33661 ttcaatcaaa tctgcaatag cttttgcgct atcaatcgtc tttcccccac caagaccgat
    33721 aatactatca caattttctt tctcagccaa ggcaacaact cgattgattt cattgtcaga
    33781 agcttcacca ttaaatagcg ccagaacaat atggaaacca tacctatgta gataatcttc
    33841 aaatcgtttt ccaacaatat cataaaccaa ctgatcgcat aatagaatcg ggtaatttcc
    33901 caaatccaaa attgatttgg cattttcaaa caaggcattt tccccctgaa tatatctaga
    33961 aggactagca aaaattctca tatgtatttc ctctctatct aaatggaact actattttga
    34021 gtaacaaacc aatcgtcaga aaaatcatca accgcctttt ggatagatgg catggcgaaa
    34081 gctgattcaa aaacatctgc tcctgctgta acagcatgcg cacctgcagc taaagcatta
    34141 tttacttgtg ctacattttt aaaggatgca gctaaaatct tactaggaga gttctgtcta
    34201 tcaatagcaa gagctaattg acgaatgaca gaatttgaat caatgttcag attttccatt
    34261 ctattataat atggagctag gtaatccgct cctgcttcga tagctaataa tccctgaata
    34321 actgtataaa tagctgttgc agtgatatgg tagccctctt tttttagcac ctttattgca
    34381 cgtaatccag ctggagtaac aggtactttg ataaatatat catctcctgc ttgtcttcga
    34441 atttcatgag catcctttaa gatgccttca aaatcttgag aaatcacctg aacatgaata
    34501 gagggtgtag agccaatcaa ttctcttaca tctttgattc gttcaaaaaa attaatagaa
    34561 ccctctcttt ttgcaatagt gggatttgaa gttaccccag ctagcggcaa aatttcagac
    34621 cactttttaa tctcatctaa atttaatgtg tcaagcataa attccataaa aagaacctct
    34681 ttattttaca aagtatgctc agtacgtcct ataatgtcat cttgggttgc cttagaaaga
    34741 acattgaaga atgcagagta tcctgcaaca cgaacaatta agtctctgtg tttttcagga
    34801 tgtttctgag cgtcaatcag cgtctctctg gaaacaacat tgtattgaat atggtaccca
    34861 tgtaaacgat taaagaatgt tcgtaacaaa gcaattagtt ttaatttatc ttcttctttg
    34921 gctaacgttt gaggatttac tttctgattt aagagaaccc cacctacgat ttcatctgtt
    34981 ggtaattttg aaacagattt taaaacagat gtagggccgt gttgatccat attatgtgat
    35041 ggtgaacaac cctctgctaa cggtgtaccc gcgttgcgtc catctggagt tgctaatgtt
    35101 ccacgtccct gccctacgtt ggctgagata gaagatgttc ctgaataacg aattcctcca
    35161 attggacctc ttccataacg tgtattagga tatttagcaa tttcatcaac ataaatgtca
    35221 taagcagcag taaccaattt gtcagcataa tcatcatcat taccatactt aggtgcatca
    35281 tgaatcaaca tttcttgaat gaccttacct tcttctccgg cataatctgt ttccagtgca
    35341 tgccaaagct gacttgggct tatacgttct tcctcaaaca ccaatttttt aattgcagct
    35401 aatgaatccg acaaatttgc aattccaact tgcaatcctg atatataatc atatactgct
    35461 ccaccttctt taaggtgttt tccacgacca atacaatcat cagtcaatgc tgaacataga
    35521 atatcaggaa cttctcgttc caatgataaa tcaatagaat tttcaacaat aacactcatt
    35581 cgtgtcaaat atcttagtgt tttatcccaa gcattttcta attcagaaaa gttcttcata
    35641 tccttaaaat gaccaaagct tggtgcaaac cgtttacccg aagccggatc aattccatca
    35701 ttcatcgtga taagtagaac cttagggaag ttcatataac tcatacctgt gcaacgatag
    35761 ccccatttcc ctggaactgc cgtttcaaca catccaatgg cactgtaatc ataagcatca
    35821 tcttccaata ctccttttgc aataaaagaa ggaataataa tctcatcatt attaaatgca
    35881 ggcataccaa aaccaagttt catcacttca atacactcat tcatgaaacg agcatctaaa
    35941 cctgcatggt aacgtacagt tagattaggt tgcggtagat gggtttgtgc aactgatttt
    36001 aataccaaat aagataatgg gttaacagca tccttcttat ctcgagtctg tccaccaatt
    36061 gtaacatttt gatataaagg acttcctgct gaagaaaatg tatgtgattg actgcgaacc
    36121 ttattaattg taattgtctt aatccaaaga tttgtcagac gttcaacaat gctatcttct
    36181 gtttctttac cactttctaa atcagccttc atatatggat acatatattg atcaaaacgg
    36241 ccatatgaaa gagagtggcc attagattca atttgtaaaa tacattgaat aaaccaaact
    36301 gattgaatag cttctgcaaa agtagttgcc ggttcatatg ggactctaga gcaaatatct
    36361 gcaatctcaa gtaattcttt cttacgttta ggatttgcat tttcggctaa acttttagca
    36421 agagcaacaa agcgctttgc atatacttta atagcatcga ttacgataaa tatagagtcg
    36481 taaaaatgat atttatcaat acttgctgga tctgttaaat ctagagctac ttttgcttta
    36541 cgagcccgct cttcaaaacc tcttaaacca aattgcaaaa gtttctgata gttaactgct
    36601 aagtgagcat ctccagaatt catcttacct tccataccga agaatcctgt ttccatataa
    36661 actgacactt cttcaggtaa taaggcacca gctctagcac gtaaattatt attttcccaa
    36721 aacggagcaa tacttctaag ttgttctttt gtttcttctg taatatagaa aacatctcca
    36781 tcacgctttt caaaaagatc caactcatta agaacaaatt ctagcgtata ttccggaaaa
    36841 ataggagcat ctttattgga agaagcttga tttcccgcaa tcatagattc ttcttcaata
    36901 tagatagaca tattttccaa aatttctttc agcatatatg cacgttttag gacattaggt
    36961 tgttccttgt atcgttcata ggcgcgtgtt gctagaactg ctctctcagc atcaatataa
    37021 ggttttttat ttaaaacatc ttctcgatat ttgttcatcc tttcagtaag gctgccaaaa
    37081 tattctgtct tgattgttgt tcttgctact tctgtattta ccatcgtaag cacctttctt
    37141 tcgaaaatat ttttatttct ttcgaaaata taataccgat ttttatagaa attttcaagc
    37201 ttttaactag aaaaatttta actctctaat ttttagcaca aatgtgtgag tttaacagta
    37261 acacacaaat acctctaaga ttgtttgatt tcattttggt aagctaaacg atcttgtatc
    37321 ttaaagaatg gaaagtaaac cactgtagat atcaccaata ctaataactg agtcacaaca
    37381 ccttgccatc cacccaccaa aaatcctgat agaatagctg gtgtactcca aggcaatgtt
    37441 acccctgaga atggctgcat gaaacctgtt gcaatagctc catatactat cacagctgca
    37501 agtacaggaa caagaatgaa aggtacaaac ataactggat tcatgacaat cggaaatcca
    37561 aatacaactg gctcatttac gttaaatatt gctggaaaag ctgcaacttt tcctaaggct
    37621 tggtattgtt ttgattttgc tgcaaaaagc atggcaacta caagaccaaa cgtaatccct
    37681 gaacctgata gaattaaaaa tgaatctaaa aattgttgag taacaatatg tgcaccattt
    37741 tctaatgata gattaccaga ggctaacata gctttattag catcaagatt agataaaagc
    37801 agagctgtca ctactccatt tactaccgat tgcccatgaa caccaaacca ccacaaaaat
    37861 gatataaaga atgcaattcc aatagcacca tacaaagatc cagttaaacc ttgcaacgga
    37921 acttgaatag cagaataaat catttctatg aatgttccgc cattagtcaa tgacttcgct
    37981 aaaatatata caatcataga agataagaaa attacaaatg ctggaatcat tgcttcaaac
    38041 tgtttggcaa tagcttgtgg aacttgttct ggcatcttaa taacaatttt tctctttata
    38101 aagaaggtat aaatacttcc tactaccaaa cctataatga tagcaccgat aattccttgg
    38161 cctccaaacc aaactttact aatagcgtcc ccaatcgcct caccttgttt agggatataa
    38221 gatgatctta gcaaaataaa gaatgcagat acagatagaa ctccagctgg taaagcctct
    38281 actccgctat tcttagcata agaataggca attgaaaaac aagaaattag acccataata
    38341 gcaaaagttc ctgaatatac ttgcataaac ggctctgtcc aattagctcc aaaaacacta
    38401 gcaatgctct tatttaatcc ttcgaacggc aattgtccca taatcaagaa caaactgcca
    38461 actactgtca atggcaaaat tgctaacatc ccatctttta gagctataat gccacgcata
    38521 ttcacaaact tcatcatcgg tgcaatgatt ttctgaacat ccatctttga cataataaat
    38581 ctccttttct tacccactaa tcaaagatag ggccaaatct aatacttttt tcccatctaa
    38641 cataccatag tccatcatcg gaataacagc tatcggaaca tcacacttat cacaaatttc
    38701 ttttgattta tctaatgtat aagcaacttg tggacccaat agtgcaacat ctatatttgg
    38761 cgcataatcc gctaatttag actgagaaaa cgcctctatt tctgcctcaa ctccactaga
    38821 ttgcgctgca attttcatat tatttacaag cataccagta gaaaaacctg ctgcacaaaa
    38881 caaaccaatc ttcaccatta tgttttcctc ctctatgtta ataacaatga taatactcta
    38941 gtattatttt ttatgaagtt cttttctcaa actaataatt tctttgatta aattaatctc
    39001 cgtcatacta gtcatgagat gatcttgtga atgaacaaag agagctgtaa tttctgtctt
    39061 tgtaccagac gcttcctgtg ccaagaattt tgtttgtaga ttatgagctt ctaataaggc
    39121 tgcatcagct aactggattt cttcttcaca ccgttcacat gtaccatttt ttatgtaatc
    39181 taacgcttta taaatatgtt gtttcgcatc accagcatat aaaattaaac ccatgataat
    39241 ttgatctgga acaataattt ccataaattc ctcctcattt cactatgtaa aaagcttttt
    39301 tcatttgaaa ttttaaaatt ttcttttgta actatagaat acaactacat aataaagttg
    39361 tcaatccaaa aacaacagat aaactatttt tgtttatata agcacaaatg tgcaatcaac
    39421 taaaaagaaa aacgataaac tgaatcagtc tatcattttc actcacctag aatctctcta
    39481 aaagtcaaat ccccatcttc ttccaaaact tttaaaattg tatttttgtc tgtaatcaaa
    39541 tgatttacta aattagcacg caagacagaa agaatcgaag attctttcgt atcaccgtaa
    39601 gcaacagcta aactttgagg aatatttttt aaatcttcca aagagattgc tatcgttctt
    39661 tcctgtaagt tttcatagac ttctttacct tttgaatcaa aaaatcgaca acaaatttct
    39721 cctacagttt taactttggt caattcttta aagtcatcct ctgtaagcat gtctaaccat
    39781 tgatgctttc ctttattgct aaaatcacca attccgacta cagctatatc taaatctttc
    39841 caactatttt tcaaattttc aaaatatctt gattgcaaaa taccatctgc taacaattta
    39901 ttttcttgca caatcgttgc attcataaat gtacactctc catgaaattt tctagacatt
    39961 tcataaatca gtgtattcac atggtattta gcgtgtatgt gactaggacc acctgctaga
    40021 ggatagaagt gaacatttcg gacactttta ctgtgaatta aatctactaa attacttaaa
    40081 cttttccccc aagaaaagcc aattttcata ttatcatcaa ttagattcct aaggacacct
    40141 gctgcaactt gagaaattct ttcagataaa attgttggat tatcatcaaa ttcatttgga
    40201 ataatttcta aactttccag accatatttt tcttttacat aattttccaa cttaaacata
    40261 ttggtatcaa aattctctat ttcaatttta acaattcctg cattccttgc ttctgttaac
    40321 attctactaa tagaggttct ataaattcct aattttgctg ctatttgtga ctgatttaag
    40381 ttttcaatat aatacagata agcaatttta gagagcagtt tattcctatc ttgattcata
    40441 cacttaacct cttacgaaac taccttaacc attatcccag cattttctaa tgtagccata
    40501 ttttgtttag aaagtttttc gtctgttatt acttcataga cttgacttaa agcaaatctt
    40561 cttactgtac cccttttatc aaatttactt gagtcagtta gcacaatgac tttatccgac
    40621 gctgctgaaa tatattgaac tacctcactg cgcattaaat cttttcctgt aaagcccatc
    40681 tctttatcgt agccatctgt cccaacaaaa gcttgacgca catgaaaagt ctgtatcatt
    40741 tcttttaata aaggtcccac agtaacctgt gaatccttct gaaactctcc accaagaaca
    40801 ataatacgac atgaatcata agctctcaca aaatttgcta taaaaaatga atttgttaca
    40861 atcgtaacat ttcttttttg cttgcaaatt tcctcagcaa gtaaagcaca ggtcgatcca
    40921 gattctatca ttattgtttc attatctgac accaatttta ctgcttcctg aacaattttt
    40981 ctcttaattt catagttaat tgacaaacgt acatttaagt catctccact atttaataca
    41041 gcatatccat gctctctgtg taataaacct tttgactcta atttatctaa atcttttcta
    41101 atcgttactt tcgatacatt taatttttcc gataatgtat taacgtcgat cttttcatat
    41161 tctgatacta atttaataat ttgttccaat cttttcattt tacacctccg ttttattcta
    41221 ccaaaataaa aagcaaaaaa caacaaatta acctttcgtt cgtaattgtt tttctttcgt
    41281 ttttgtgata ggatagactt atgaagagga ggaactctta tggaaatatc taaaggaatt
    41341 atttttaata ttcaacactt ttcaattcat gacggtccgg gtattcgtac aactgttttt
    41401 ttaaaaggat gtcctctgcg ctgtccatgg tgttctaatc ctgaatctca aagaatgaaa
    41461 cctgaaaaaa tgaaagatgc tcaacgagag aaattcacct tagtcggtga agaaaagact
    41521 gtagaagaaa ttattacaga ggtattaaaa gacaaagaat tttacgaaga atccggtgga
    41581 ggtttaactt tatcaggagg tgaaatattt gctcagtttg aatttgctaa agccatctta
    41641 aaatcagcta aagaacatca catacacact gccattgaaa ctactgcctt tgttgatcat
    41701 gaaaaattta ttgatttaat tcaatatgtg gattttatct acacagacct aaaacattat
    41761 aattctataa aacataaaaa agtgactggg gtttttaatc aaatgattat taaaaacatt
    41821 cattatgctt tttctcaaaa taaaactatc gttttaagaa tcccagttat tcctaatttt
    41881 aacaatagtt tagaggatgc agaaaaattc gctactctat ttaactcatt aaatatcgac
    41941 caagttcaac tactcccttt tcatcaattt ggtgaaaaca aatatcgttt attaaatcgg
    42001 aaatatgaaa tggatggagt caacgcactt catcctgaag atcttattga ttatcaaaag
    42061 gtatttctga accaccatat taattgttat ttctagttta tttccttgaa atgctctagc
    42121 tatttgcaga taacaagcat ctatataagg ttatcaaaga agacttcccc atgactctaa
    42181 atgaatatat cttacaatat cgcctgaaac aagctataga taagatggct gaatctccca
    42241 actcctcttt aagcgatatc tctgaccaag ttggattttc agactataaa tattttgcca
    42301 aagtatttaa aaagtatctc catatttccc caaagaaatt gaaatcactc ggaagaatag
    42361 taaaataggc tattcttctt tttgtagaga attttactct aatatagtga attgaaataa
    42421 gatgtgaaca tctctatcag gaaagtcaaa ttaatttata gaaatatttt agcagtcaaa
    42481 gtgtactgtt atagattcaa tacactatag aatagaattg taggttttaa aaacgcttac
    42541 attgttttaa aataaactta aataacacaa cggaggtatc catcatgaaa aagaaatgga
    42601 tgtattatgc tgcttgttct tctaatgaat ctgccgatga cagttcatct gataaaggag
    42661 acggtggttc gctagtcgtt tattgaccaa actcagaagg cttaattgga gcaactattc
    42721 ctgcctttga agaaaaatat ggtatcaaaa tagaactgat tcaagctggt actggagaac
    42781 ttttcaaaaa actagagtca gaaaaagaag ttcctgtagc tgatgttatc tttggtggtt
    42841 cttatacaca atatgctacc cacggagaac tctttgaaaa ctatatttca aaagaaaatg
    42901 ataatgttat caaagaatat caaaacacaa ctggcttctc tactccttat acactagatg
    42961 gtaatgtttt aatcgtccac cctgatttaa ctaaaggcat gaacatcgaa ggatatagcg
    43021 accttctcaa acctgaacta aaaggaaaaa tcgcaactgc tgacccagca aactcttcta
    43081 gcgcctttgc tcaattaaca aatatgctac aagctcaagg tggttacaaa gatgataagg
    43141 cttggtctta tgtaaaagat cttttcacac ttattgatgg tatagtaaaa tgaaataaga
    43201 acaggacaaa ttaatcagga cagtcaaatc gatttctaac aatgttttag aagtagatgt
    43261 gtactattct agtttcaata tactataaaa tcggttcaag ttcatctggt gtctataaag
    43321 cagtcgctga tggagaaatg actgttggtc tctcttatga agatccagca gttaaactct
    43381 taaatgacgg agctaacatt aaggtagtct atccaaaaga aggaaccgtc ttcctacctt
    43441 ctagtgctgc tatcgttaaa aaatctaaaa atatggaaaa tgccaagaaa tttatcgatt
    43501 ttattatctc tcaagaagta caagatacac ttggtacaac cactactaac cgtcctgttc
    43561 gtaaaaatgc taaaacaagc gaaaacatga aaccaattga caaaatcaaa acactcactt
    43621 aagattatga ttatgtcatc aagaataaat cagatatcgt taagaaatac aacgaagtct
    43681 ttacagatat ccaatctaaa cagtaaaaga ggttcactat gagtgagatc gaaattatta
    43741 acgccaaaaa aatctaccac gatgtccctg ttattgagaa tttgaacatt acaattccaa
    43801 aaggaagtct ctttaccctt cttggagctt caggatgtgg gaaaacgacc cttcttcgta
    43861 tgattgcagg tttcaacagt atcaaagatg gagaatttta cttcgatgat acaaaaatca
    43921 ataatatgga acccagcaaa cgcaatatcg ggctggtttt ccaaaactac gctattttcc
    43981 cacatttgac tgtccgagac aacgttgctt ttggtcttat gcaaaagaag gttccaaaag
    44041 aagaattgat tcaacagacc aacaagtatc ttgaactcat gcaaattgct caatatgcgg
    44101 atcgaaagcc cgataaactc agtggtggac aacaacaacg tgtcaccttg gcatgcgcct
    44161 tagcggttaa tccaagtgtt ctcctcatgg acgagccact tagtaatctg gaggccaaac
    44221 ttcgcttgga tatgcgtcaa accatccgag aaatccaaca cgaagtggga attacaactg
    44281 tttatgtaac ccacgaccaa gaagaagcca tggctatttc agaccaaatt gctgttatga
    44341 aagatggggt gatccaacaa atcggccgac caaaagaact ctatcataaa ccagctaatg
    44401 agtttgtggc aacctttatc ggacgcacaa atattatccc tgccaatctt gaaaaacgga
    44461 gcgacggcgc ttatatcgtc ttttcagatg gctatgccct tcgaatgcta gctcttgatc
    44521 aggttgagga gcaagctatt catgtaagca ttcgtcccga agagtttatc aaagatgaat
    44581 ctggagatat cgaaggaact attagcgata gcgtctatct tggactaaat acggagtatt
    44641 tcattgagac aggttttgcc tcaaaaattc aagttagtga agaatcaact tttgaagaag
    44701 atctacaaaa aggcaatcgt attcgtctac gaatcaatac gcaaaaatta aacatctttt
    44761 ctgcagatgg ttcccaaaac ctgataaaag gagtcaacca tggaatgtaa aaaactaaat
    44821 atttggacag cctcctcttt cttcctcttt cttacctatc ttgtctttct cgtttatcct
    44881 atcgttaccg tgctcaagca agcacttata catgaaggac aattctcact agctaatttt
    44941 gtcactttct ttagtaaagc ctactactct gagacactag tcaacagttt cagggtttcc
    45001 attaccgcta ctgtcacttc cttagttgta ggaaccctat tagcttatct cttctctatg
    45061 tatgacttca aggggaagaa atttctacaa atattgatta tcattgcttc catgtcagct
    45121 cctttcgtag gagcctactc ctggattctc ttgctgggac gaaatgaggt catcactaaa
    45181 tttttgacaa atgcccttta tcttccagct atcgatattt atggattcaa aggaattgta
    45241 cttgtcttta cactgcaact attcccactg gtatttctat atgttgctgg aacaatgaac
    45301 agtattgaca attctctact tgaagcagct gaaagcatgg ggtccttcgg atttaaacct
    45361 atcgtaacgg ttgttttacc tctcctagtt ccaaccttac tagcagctcc ttgcttgtat
    45421 ttatgagagc attctcagac tttggaacgc ctatgttgat tggcgaaggg tatcggactt
    45481 tccctgtcct gatttatacc caatttatta gcgaggttgg aggaaattct gcttttgcaa
    45541 ttatggcgat tatcattgcc ttggcaattt tccttatcca aaaacacatt gcaaaccgct
    45601 acagtttcag catgaatctg ctccatccaa ttgagcctaa aaaaactaca aaaggaaaaa
    45661 tggctgccat ttatgcaaca gtctacggaa ttatctttat ctctgtttta cctcaaatct
    45721 acttaattta tacctctttc ctaaaaacat caggtatggt atttgttaaa ggttattctc
    45781 caaacagtta caagctagct ttcaatcgta tgggatctgc tattttcaat accattcgta
    45841 tccctttgat tgccttagtt ctagttgttc tatttacgac atttatctcc tacctagccg
    45901 ttagaaaacg gaatttgttt acaaacttaa ttgacagcct cagtatggta ccttatattg
    45961 taccaggaac cgttctaggg attgccttca tttctctggt ctatttggaa gtggatttct
    46021 tatgattaca gggactgctt tcatcttgat tatgtctcta tctgccagaa aattacctta
    46081 tactattcgc tcatctgttg ctagcttaca acaaatagca ccaagtattg aagaagctgc
    46141 tgaaagctta ggaagtagtc gtctcaatat ctttgctaag attacaactc caatgatgct
    46201 atcggatatt atttctggag ccatcctatc ttgggtcaca ctgatttcag aactctctac
    46261 ttctatcctc ctctacaatg tcaaaacaag aacaatgact gtagctattt atacagaggt
    46321 tctcagagga aattacggtg tagctgcagc cttgtcaact atcctgactg ttctaacagt
    46381 aggttccttg ctcttgttta tgaaaatctc taaaagcaat agcattacac tttagttttc
    46441 cacatcaaaa acagccgaaa ggagtaccct cggctgtttt ttcttatctt gatattctta
    46501 tcaaatccct agctcatggc aagcaagtct agactgatta aatagagcct tcttccatct
    46561 tctcacgtcc tagctctcgg taactacggt caccgacaac ttcaacccta aactgaccgt
    46621 cctcatattc aagaatcgtc acgctaccat tatctagacc atgcggatgc atgccattaa
    46681 tcagataaac aatggttcca atagtcattc catggctgac aacaagggcg ttacctccac
    46741 cttgatcttc catttctttt gcaatcattt caaagccttc cttgattcgg ccactgagtt
    46801 tttcccagcc ttcagcccaa ccagctgtat cgacctctac caagccctca gccagttcag
    46861 cataagacaa ttggtgaacg tggtccacat taaagatacg aggaataatg cccatgaaaa
    46921 gatcgccatc ataggctcca tcaaaactac cgaaacacca ttctctgata cgcttgtcca
    46981 tgcgataagg gattttcccc tgcaagccaa gttcttcaag gataattccc atggtctgaa
    47041 tggtacgacc agaatcactc gaataagcgc gctcaaactg tagatcagat tctcgcaaac
    47101 cgattcctaa ctcttgaatc cctcgttcac cttcagcagt taagggagta tcgctccaac
    47161 cttgcgcgcg accaatcgtg ttaaacatgg tcttgccatg acgtaccaaa tacaatcgta
    47221 cttttaccat tttccgtcct ccgtttgctt ctattatatc atgaatgata aaataaaagc
    47281 cacccataca ggcgactttt gaaggagatt attatgaaaa agtttaggag ttcattaaat
    47341 aaagatatta gatgaaaatc aaattcaaac taattcagtg ttatctgttt caaataatat
    47401 taggaggtct ttatttaatg attatagtat acacatctaa tcttaaatag aacttaaaat
    47461 ttctcctatt ttcttaattt ttaaaactat gaattggtgc tgggatttgt ccaccgcgag
    47521 agatgaagtc gacagacgaa gccccattaa ccctcataac gggtgcagtt cctaatagac
    47581 caccaaactc aatcatatcg ccttcttttc ctttgggaat gatacgaaca gctgttgttt
    47641 tcatgttgat aacaccgatt gctgcttcat ccgcaatcat agccgcaata gtttcagcag
    47701 gcgtatcttc tgggatggca atcatatcca atccaacaga acagatagcc gtcatagctt
    47761 ctagtttttc taaattaaga gagccatttt gcactgcagc aatcattcct tcatcctcag
    47821 aaacagggat aaaggcacca gataaaccac cgacctggtt acaggccatc actccaccct
    47881 ttttaacttg gtcgttcaag agggccaagg cagccgtcgt tccatgcgtg ccaactgttt
    47941 ctagccccat ttcctcaagg acacgtgcca cagagtctcc aaccgcaggg gttggtgcca
    48001 aactcaagtc cacaatacca aactccacac ccagtctctc actggccatt tgaccaacca
    48061 attgaccgat acgagtgatt ttaaaggcag ttttcttaac tgtttcggct actacatcaa
    48121 agctctgtcc acgaactttt tccaaagcac gtttcacaac accaggacca gaaactccga
    48181 cattgatgat aacatctgct tccccaacac catgaaaggc acccgccata aatggattgt
    48241 cctcaacagc attagcgaat acaaccaact tggccactcc catatctgaa agatttgctg
    48301 tttccttgat aattcgtccc atatctgcca cagccgtcat attaatacca gacttggttg
    48361 agccgatatt gactgacgag cagaccttat ccgtctcagc caaagcgcga ggaatggaat
    48421 tgatgagaat ctcatctccc ttttgataac ctttttgtac taaggcagaa aaaccaccaa
    48481 taaagtccac accaatctct ttcgcagcct tatcaagcgc ttttgccaga accacgtagt
    48541 ccgtcgcatc tgtcgctgcc ccaatcagag aaataggtgt caccgataca cgcttattaa
    48601 cgataggaat tcccaactca gccgcaattt catcaccaac agctactaaa ttagccgcct
    48661 ttgtcgtaat tttttgatag attttctccg cagcacgatt gatatctgga tcgatacagt
    48721 ccaaaagaga aatccccatg gtaatggttc tgatatcgaa attttgctcc tcaatcatgg
    48781 cgatggtttc agtaacttgt ctaatatcca tgataacctc ctagatatta tacatagctt
    48841 cgaaaatcgc tgcactctga atattgattt ttacattcaa agtttgccca aaagcttcaa
    48901 attcattacg aagataggta aaatcttgct tttcatcact agatacaata gccatcatcg
    48961 taaaatattc atccaagaca gtttgagaga tatcgtcaat attcaatcct aattctgcaa
    49021 ttttaccaga aacacctgca acaattccag atttatcttt accaacaaca gttataatcg
    49081 ctttcataag caaactccaa ttcttcttaa aataagaaac cttaacatta aacaggattc
    49141 ttttcaaata gtatagcata attctaacga aaatactcaa aaacgcctgc ttacgaagtt
    49201 gttcttaaga aaaaaacaat ttcgtaaaca agcgtctact atcccaactt atgatgagtg
    49261 ttcccgctag gaccgaaatc ctagcggtag accagagcta gactaagagc acaagactcc
    49321 atcatcataa cactcaacaa aattgatgat tttatactaa ttcgatgatc gccattggcg
    49381 ctgcatcacc acgacgtggt tcagttttaa ggatacgagt gtatccaccg ttacgttcag
    49441 cataacgagg tgcgatttct gagaacaatt tttgaagtgc tgtagtagaa gtgtacttat
    49501 cagttgcttc atcatagttt tcagatgcga tttcattacg tacgaaagca gctgcttgac
    49561 gacgtgcatg caaatcacca cgtttaccta gagtaatcat tttttcaaca gttttacgga
    49621 tttctttagc acgagcttca gttgtcacga ttgattcgtt gatcaaaagg tcagttgtca
    49681 aatcgcgaag cattgcttta cgttgtgagc tagtgcgtcc tagtttacgg taagccatgt
    49741 attcctcctt tatttatctt ttaatccaag acccaaatca atgagtttga gtttcacttc
    49801 ttccaaactc ttgcgtccaa gatttcgtac tttcatcatc tctgcttcag atttttctgt
    49861 caaatcatgc acagtattga taccggcacg ttttaaacag ttgtatgaac gcacagacaa
    49921 gtccagttcc tcaatcgtac gatctaaaat acggtcgtca gattcagtat cagcttcttt
    49981 catcacttca gttgacttag caatctcagt aagatttgta aacaaatcaa gatgttctgt
    50041 caaaatacgt gctgaaagcc ctaaagcatc ttctggaata attgttccat ttgtcaagat
    50101 ttcaagggtt aatttgtcga aaccatcatt gctacctaca cgagcaggtt ccacttgata
    50161 gttgactttt gtaactggtg tataaataga atctacagca agtgttccaa ctggtgcatt
    50221 atccttttta ttttcatcag caggtacata tccacgacca ctgttaacag tcatagtcgc
    50281 ttttagagaa gaaccttcac cgattgtaaa gagataatga tctggattta caatttcaat
    50341 atcgctatct gtcaaaatgt caccagctgt tacttcagca ggaccttcaa catccagttc
    50401 gatgattttt tcgtcttcaa cgtacgattt cactgcaatt cctttaatgt tcagaatgat
    50461 ttgcatcacg tcttcacgaa cacctggaac tgtgtcaaac tcatgtaaca caccatcaat
    50521 gttgatagat gtcacagctg ctcctggtag agaagctaga agtacacgac gaagagagtt
    50581 accaagagtt gtaccgtagc cacgttcaag tggttcgatt acaaacttgc cataatcttt
    50641 attttcatca atttttgtta tatttggttt ttcaaactcg atcatttagt tactccctct
    50701 taaacgaaaa gcagtgtaat gcgatgatta tacacggcga cgttttggag gacgagcacc
    50761 attgtgtggc actggagtca catcacgaat tgctgttact tcaagaccag cggcagcaag
    50821 cgcacgaata gctgactcac gaccagaacc tggacctttt acagtaactt caactgattt
    50881 aagaccgtgt tcttgtgcag atttagcagc agcttcagaa gccatttgag cagcgaatgg
    50941 tgtagattta cgagaacctt tgaaaccaag agcaccagct gatgaccaag caattgcatt
    51001 accatgcaca tcagtaatca taacaatagt gttattaaat gtagcgtgaa tatgagcaat
    51061 accagattcg atattctttt tcacacgacg tttacgtgtt ggtttagcca agacttttac
    51121 ctcctatatt attttttctt accagcaatc gcaacagctt tacctttacg agtgcgagcg
    51181 ttgtttttag tgttttgtcc acggacagga agtccacgac ggtgacggat accacggtat
    51241 gaaccgattt ccatcaaacg tttgatgttc aagtttactt cacgacgaag gtcaccttca
    51301 actttgattg catccacttc acgacggata gcatcttctt gatctgatgt aagatcacgt
    51361 acacgaacat cttctgagat tccagcagca gccaaaattt tcttagatgt tgcaagtccg
    51421 ataccataaa cataagtcaa tgagattact acgcgtttgt catttggaat atcaactcca
    51481 gcaatacgag ccatgttttc tcctttctat cttatccttg acgttgtttg tgttttggat
    51541 ttgctgggca aattaccata acacgaccat tacgacgaat aactttacag tattcgcaaa
    51601 ttggtttgac cgatggtctt actttcattt cttatccctc caagtttttc gattatttaa
    51661 agcggtaagt gatacgtcca cgtgtcaagt catatggact catttcgaca gtaacacgat
    51721 ctcccgctaa aatacgaata tagtttttac gaattttacc agaaactgtt gctaaaatct
    51781 gatgtccatt ttcaagttca accgtaaaca ttgcattcgg cattgtatca actactttgc
    51841 cttcaacttc aatcacatcg tcttttgcca cgcaaaagca cctccataaa tttcgattcg
    51901 atgcctctag acacagagac aacaattata agtcagacta tctcagtata acatttgtag
    51961 cggattttgg caagtgtgaa aaacgcttta tttcaaattt gtcaatactt tttcaatatc
    52021 tgagaagaca tcattgatat cttgattacc ttcgatgtca tgaaccaaac ctttggcacg
    52081 gtagtgagca atgattggtt ctccttgagc aatattaaca tccaaacgac gttttactgt
    52141 ctcaggctta tcatcttcac gttggtagta atcttcttct ttatagtcaa ctggtgggtt
    52201 aaagaccttg tggaaagttt ctccagttac gcggtggatg atacggccac tcaaacgttc
    52261 caaaaggctg ttagggttca cttcaatatt gataacacct tctagttcaa tgccaagttc
    52321 agccaatgtt ttgtccaagg cctgagcttg ttcaattgta cgtgggtaac catccaataa
    52381 gaatcctgtt tctttaatat catcttgtga aagacgttct tttacgattc catttgtaac
    52441 ttcgtcagga accaattcac ccttgtcaat atatgactta gcaagaacac ccatttcagt
    52501 ttgatttgcc attgcagcgc ggaacatatc acctgttgag atatgtgcaa catggaattg
    52561 ttctacgatt tttgctgctt gagttccctt acctgcacca ggtaagccca taatcaaaag
    52621 attcatgatt tgatctcctt attttatttt taaatagaag caaaaagtct tttcacccct
    52681 atttaaaaac aaaatagaag aggggagatc caactcttac aaatgtcaga gtttaaacct
    52741 ccactccctc agtatttact gattcagtaa atacttttat tctgttctgt ccatgaaacc
    52801 aacatactta cgtttcaata ggtaaccttc caattgcttg attccttcga tacctgtaga
    52861 gataatgatc aagagacttg ttccaccaaa ggcaacaaca tcagaaagac caaatacatc
    52921 tttagctgca atcggtaaaa tggaaatcac accaaggaag agggaaccaa cagttgcaag
    52981 acgacgaaga agtttagaca tatattcttc tgtaccttta ccaggacgaa ctccatggat
    53041 ataggcacca ctcttttgta ggctctctgc tgctttttca ggattaatct gtacaaacgt
    53101 atagaagaat gtaaagagaa taatcaacaa agcatacatg gcaataccag ttggagaagt
    53161 agttgccaac atctcttgtg ctacccttac ccaagcccaa tcatgacctg tggcactcaa
    53221 aaactgaaga atagccgcag gcgctgcagt aatcgaactg gcaaagataa cagggataac
    53281 tccagcagga tttaccttta acggaaggta agagctagat ggagcacctt gtgcaacctt
    53341 agtatattgg attggaattt tgtattctgc ttgttgaaca taagttgtaa agtaaataat
    53401 caacaataca gtaataatca aaatgattac gaaaatgata gatgaagtga tacggctact
    53461 tgggacgttc acaaagtagt ccacatagat gccctgaatc atctctggaa ttgaggaaac
    53521 aatcccggca aagataatca tggaaacacc gtttccgtat cccttatctg taatttgctc
    53581 acccaaccaa gtgacaatca tactaccagc tgttaagatg ataccaatcg tcagaaaaac
    53641 ttgtggagtt aaagcagttt taatcaattg agctccagcc aaggtattaa aaccagctgt
    53701 aatcccgata gattgcacaa aagcgagaac tagagcaata taacgagtag cttgattcaa
    53761 ttttcttcga cctacttccc cttgtttacc ccactctaca aacttgggta aaatatccat
    53821 ttgcaagagt tggacaacaa tagaagcggt gatataggga ctaactccta gggcaaaaat
    53881 cgaaaagttt tttagggcat tccccgacac caagctcaac atgtttaaga aggataatcc
    53941 acttaaagca ttcaagctat tggcattcac accaggaact gtaatgctag ttccgatacg
    54001 aaagaccaaa acgataaaaa ttgtaaataa aatttttgat cgaacctgct tgactttaag
    54061 agcttctctt aataatttaa aaaacatagg tcacctctct tagatgactt ctactgaacc
    54121 acctttagca gtgatagctt cttcagctga tttagagaat ttagctgctt tcacagtcaa
    54181 tttcttagtc aactcaccgt taccaagaat tttaatacct gacttttcag ctttaacaat
    54241 tcctgcttcg ataagaacaa ctggagttac ttcagcacca tcttcaaaga cgttcaattg
    54301 gtcaaggttc acaattgcgt attctttagc gttgatgtta gtgaatccac gttttggaag
    54361 acgacggaac aatggagttt gtccaccttc aaaaccaagg cgaactccgc caccgctacg
    54421 agctttttga cctttttgac cacgaccaga tgttttaccg ttacctgatg aagtaccacg
    54481 accaacgcgg ttacgtactt tacgagaacc ttctgcaggt ttcaattcat gaagtttcat
    54541 ttttattttc tcctcttttg taaaatgcta gcgccgataa gggagaaaag gttgtctccc
    54601 ccatcaactc gcctatacga tgtcatcata gatgactata tctagtttta ggggatggta
    54661 cagtgcacat cccctaaaac ttcattagtt tacttcttca actgttacta agtgagatac
    54721 tgctgtgatc ataccacgga tagcagcgtt atcttcttta ataacagagc tgttcaattt
    54781 gccaagtcca agtgctacaa cagttttacg ttgtgatgga atgcgtccga ttggagactt
    54841 agtcaaagta attttaattt gagccatttt atcccctttc ttatgccaaa tcagaaactg
    54901 aaataccacg aagggcagca atttcttcag cgcgtttcaa ttgtttcaaa ccttcaacag
    54961 ttgcacgaac aatgttgatt ggagtgttag aaccaagtga tttagatgta atatctgcca
    55021 cacctgccaa ttccacaacg gcacgaactg caccaccagc ggcaactcca gaaccttcta
    55081 cagcaggttt caacaatact ttagctccac cgaattctga aagaacttcg tgtgggattg
    55141 ttgttccaac cataggaact tcgatcaagt ttttcttagc atcatctact gctttacgga
    55201 ttgcttctgg aacttcttga gctttaccag taccaaatcc tacgcgacca ttgtggtcac
    55261 caacaacaac aagagctgcg aaacgaagac gacgtccacc tttaacaact tttgtaacac
    55321 ggttgacagc aactacgcgt tcttctaatt caactgcatt gtctttaaat gccattttct
    55381 agtgtcctcc tattagaatt tcaatccgtt ttcacgagct gcatcagcca aagctttcac
    55441 acgtccgtga tatagatatc caccgcggtc gaacaccact tctgaaatac ctttagcgtt
    55501 tgcacgttct gcaacgagtt taccgacagc aacggcttgt tcagttttag ttccttttga
    55561 aacttcttta tcaagagttg aagcacttgc gagcgttaca cccgctacgt catcaatcac
    55621 ttgagcgtag atgcctgtat tagaacggaa tacgttcaaa cgtgggcgat cagcagttcc
    55681 agagagtttt ccgcgaacgc gacggtggcg tttttggcgg agtttgtttt tatctggttt
    55741 tgaaatcaca gttttcacct ctttagtttt aaatcgtgtg ctatgcacaa agttggaaaa
    55801 taggttggtg gttgatgatc aaccactcaa cattatttac ctgttttacc ttctttacgg
    55861 cgaacgaatt caccaacgta acggatacct ttacctttat atggttctgg tgaacgaagg
    55921 ctacgtacgt aagcagctgt ttgaccaact acttcttttg aaattccgct aacaacgatt
    55981 gttgttgggt ttggaagttc aaaagtaatt ccttctggag cttcaacttc gtctggatga
    56041 gatttaccaa cagccaaaac aagtttagat ccttgaagct gtgcacggta accaacccca
    56101 cgcatttcaa gttctttctt gaatccttct gatacaccaa caaccatgtt gttcaaaagg
    56161 gcacgagtag ttccgtggat agttttcatt tcttttgaat cgtttggacg gtgaagagtt
    56221 atttcagtac cttccacacg gatttcaata tcttttgaga actcacgagt aagttctcct
    56281 ttaggtcctt ttacagttac aacgttgtca ttgttagcga gttcaacacc agcaggcaac
    56341 acgataactt tattaccaat acgtgacatg tttattttct cctgttaaat tgtcaggcca
    56401 gaacggccag ttttcacggg gttcagatac ttatttagtt caagagctga actgaacacg
    56461 ctctaagaac tgtgcaaaat agataagttg gcttgtttgt aaacaaactt ctccaacttc
    56521 ctaattttgc tttgttcttt acgagctttg tatcttgatt ttaccaaacg taagcgataa
    56581 cctcaccacc aacattcttt tggcgtgctt ctttatcagt aagcaaacct tcagaagttg
    56641 aaaggatggc aattccaagt ccgttaagaa cttttggaag gtcttcacgt tttttgtaga
    56701 cacgaagtcc tggtttagaa acacgtttca agttagtgat aactttctca ccatttggtc
    56761 cgtatttaag aaatacacgg atgacgcctt gtttgtcatc ttcaatgatt tcaacgtttt
    56821 ttacaaaacc ttcgcgttta aggatttcag caatcccttt tttgatgttt gatgcaggta
    56881 cttcaagtac ttcgtgttta gcttggttag cattacgaat acgagttagg aagtctgcga
    56941 ttgggtcagt cataaccatt ttgtttttct cctcttacta gtagtttgca agttgcactt
    57001 gctagttaat acatgataca aagagcgtaa cagcacgagc aaaaatagac aatttaatgc
    57061 agaagcaatg ctccaaagca aattggtctt ttttgccaaa gctgtagctc gtgttcaaat
    57121 tggcaagccc aattgaaccc gggctaaact ctgtgtgaaa aagataaact ttcctagaaa
    57181 ctttagtttc ttcgtcaagt ttcctatttt tacttggagt tttgacgctc ttgatatctt
    57241 aaattaccaa gatgcttttg ttacaccagg aatttgacct ttatgcgcaa gttcgcgaaa
    57301 agcgatacga ctcagaccaa atttgcggta aactgaatgt gggcgccccg taactctaca
    57361 acgattatgt aaacgagtcg gtgaggcgtt gcgaggtaat ttagataaac cttcgtagtc
    57421 ccctgccgcc tttaatgcag cacgtttttc agcataacgg tcaacaattt tttggcgttt
    57481 agcctctcta gctaccattg attttttagc cattagattt acctcctata ttattttgca
    57541 aaaggcattc caaggcctgt aagcaatgca cgtgactctt cgtcagtgtt agcagttgtt
    57601 acgataacga tgtcaagacc acgagttttg tcaacgtcat cgaagttgat ttctgggaag
    57661 attaattgtt ctttcacacc aagtgtgtag ttcccgcgtc catcaaatga ttttgttgga
    57721 acaccgtgga agtcacgtac acgcggaagt gaaactgata ccaatttatc caagaattcg
    57781 tacatacgtt caccacgaag ggtaactttt gcaccgatcg caacaccttc acgaagacgg
    57841 aagccggcga ttgatttttt agctttagtg ataagtggtt tttgacctga gataagtgcc
    57901 aattcttcag cagctttttc aaggctttta gcgtttgata cagcttcacc aacacccatg
    57961 ttcaaaacaa tcttatctac tttaggcaca gccatcactg atgagtagtt gaattgttct
    58021 gtcaaagcag gaactacttc attaagatat ttttctttta aacgatttgc cattatactt
    58081 ctcctttcct tcgtgattaa tcaagcactt cgcctgattt tttgttgtag cgaacttttt
    58141 taccgtctac aaatttgtat ccaacacgac cagctacacc atttttgtcc aaaacttgaa
    58201 cgtttgatac gtggatagct gcttctttct cgacgatacc accttgagga agctcgttag
    58261 ttggacgttg gtgtttctta acaatgttaa caccttcaac gataactttg tttacttttg
    58321 gaagggcagt aaggacaaca gcttctgttc ccttatcttt accagcgatt acgcgaactt
    58381 tgtcgccttt ttttacaaac attaggtttc tccttgattt ttcttacgcc cataagggca
    58441 ccctagcttg aagctagggg actagtttgt tcctaaaaat taaagtactt ctggagcaag
    58501 tgacacgatc ttcatgaagc caccttcacg caattcacgt gcaactgggc caaagatacg
    58561 tgttccgcga ggagttttgt cttcacggat gataactgct gcgttttcgt caaatttgat
    58621 gtatgaacca tcagcacgac gagcacctga tttagtacga acgataactg ctttaacaac
    58681 gtcacctttt ttaaccgcac caccaggagt agcttgtttt acagatgcca cgataacatc
    58741 accgatgttt gcaaatttac gtcctgaacc accaagaact ttgatagtca agatttcgcg
    58801 agcaccgctg ttgtctgcga ctttcaaacg agtttctgtt tgaatcattt cagttttctc
    58861 ctttcaggtt tgattagatg atgaccgctt cttcaacaac ttctacaaga cggaaacgtt
    58921 ttgtagctga aagcgggcga gtttccatga tacgtacgat atcgccttct ttggcaacat
    58981 tgttttcatc atgagctttg tattttttag agtagttaat acgtttacca tagactgggt
    59041 ggttacgttt tgtttcaact acaactgtga ttgtcttgtc cattttgtca gatacaacac
    59101 gtccaacaag aactttacga ttattgcgtt ccattgaaat ttctccttcc ctagtctatt
    59161 atttcgcttc agattgaact gttttgatac gagcgatttg ttttttaact tctttcaagc
    59221 gagctgtttg ttccaattga ccagtagcag cttggaaacg aagttcaaac aattcttttt
    59281 tcaattcgtt ttcgcgcttc gcgagttctt cttgagaaag accacgaagt tctttaacaa
    59341 attcttttac ttcattaagt ttcatgcctt ctccttattc tgcttcacgt tttacgaatt
    59401 tacatttaac tggcaatttg tggctagcaa gtcgaagcgc ttcacgtgca atctcttcag
    59461 atacaccagc gatttcgaac atcactttac cacgtttaac tggtgctacc caaccttcag
    59521 gtgccccttt accagatccc atacgcacac cgatagcttt agcagtgtat gatttgtgtg
    59581 ggaagatttt aatccaaact ttaccaccac gtttcatgta acgagtcatg gcgatacgag
    59641 cagcttcgat ttggcggtta gtgatccagt ggctagttgt agcttgaaga ccgtattcac
    59701 cgaatgctac ttcttttcca ccttttgctt caccgcgcat ttttccacgg aattcacgac
    59761 ggtgtttaac acgtttaggt actaacattg gttatttacc tcctttagtg tttttacgag
    59821 ctggaagaac ttcaccacgg tagatccata ctttaacacc aagtttaccg tatgtagtat
    59881 ctgcttcttc ccaagcgtaa tcgatatctg cacgaagtgt gtgaagcgga acagttcctt
    59941 cagagtatcc ttcagcacgg gcgatatctg caccgttcaa acgacctgat acttgagttt
    60001 tgattccttt agctccagca cgcattgcac gttggattgc ttgtttttgt gcacgacgga
    60061 aagcaacacg ttgctccaat tgacgagcaa ttccttcacc tacaaggtga gcatccaaat
    60121 caggttgttt gatttcgatg atgttgatgt gtacttgttt tccagtcaat ttgttaagtt
    60181 ttgcacggag tgcatcaacg ttagcaccac ctttaccgat aaccatacct ggtttagcag
    60241 tgtgaagtga aacgttaact ttgtttactg cgcgttcgat ttcaatagtt gaaactgctg
    60301 cgtcagcaag ttctttttga acgaatttac ggattgcaag atcttcatga aggtaatccg
    60361 cgtattcttt ttcagcatac catttggcat cccaatcacg gatgatgccg acacgcatac
    60421 caattggatg tactttttga cccacgattt tacctcctta tttttctgca acagctacag
    60481 tgatgtgagc tgtacgtttg ttgattggtg aagctgaacc tttcgcacgt ggacggaaac
    60541 gtttcatagt tggtccttcg tttgcgaatg cttcagatac taccaagtta gctttatcca
    60601 aaccaaagtt gttttcagcg ttagctacag ctgagttcaa aactttcaag atgatttcag
    60661 cagctttgtt tggagtgaat gtcaagattg cgattgcatc ggctacgctt ttaccacgga
    60721 tgttatcaag aacaagacgt gatttacgag gtgaaacacg tactgtacga gccattgctt
    60781 tagctgaagt aatttctgcc atttatgttc tccttatttt ctacgtgttt tcttgtcgtc
    60841 tgcagcgtga cctttgtaag tacgagttgg tgcaaattca ccaagtttgt ggcctaccat
    60901 gtcttcttgg atgtaaacag gcacgtgttt acgtccgtca taaactgcaa tagtgtaacc
    60961 aatgaaactt gggaagatcg ttgaacgacg tgaccaagtt ttaataactt ttttcttttc
    61021 gtcgttagct tgagcttcaa cttttttcat caaatgctca tcgacgaaag gtcctttttt
    61081 aagactgcgt cccattttta tattttctcc tttaaatgtt gtaccacagc ggtttgcgct
    61141 cctatggagc actaccgagc tggcggattt actagttgct taagcgacta gtttaatatt
    61201 atttctcgtt gcgacgacga acgataagtt tgtcagattt cgctttcttg ttacgagttt
    61261 taagaccaag agcaggtttg ccccatggag tagatggtgc tttacgacca actggtgctt
    61321 taccttcacc accaccgtgt gggtgatcgt tagggttcat tacagaacca cgaactgttg
    61381 ggcggatacc tttccaacgg ctacgtcctg ctttaccaag gtttacaagt ccatgttgtt
    61441 cgtttccgac aacaccaact gtagcacggc aagttccaag aatcatacga acttcacctg
    61501 attgaagacg aacaagaacg tatttacctt cagaacccaa tacttgagca gatgcaccag
    61561 cagcacgtac caattcacca ccacgacctg gtttcaactc gatgttgtga atcaaagtac
    61621 caactgggat gttagcaagt ggaagagcgt ttccgacttt gatatctgct tctggacctg
    61681 aaacgatacg ttgacctact tcaagacctt ttggagcgat gatgtatgct ttcacaccgt
    61741 cagtgtagtg tacaagagcg atgtttgcag aacggtttgg atcgtactcg attgttttaa
    61801 caactgcttc aacgttatct ttattacgtt tgaagtcaac caaacggtag aaacgtttgt
    61861 gtccaccacc ttggtgacga actgtgatac gaccgttgtt gttacgacca gccttgctct
    61921 tcaatgcaac aagcaatgat ttttcaggag tgcttgttgt gatttcagcg aaatccaaag
    61981 aagtcatatt acggcgaccg tttgttgttg gtttataaac acgaattccc acgatatttc
    62041 ctccttagat tattcagctt cagcagcaaa caactcgatt gctttagaat cagctgtaag
    62101 tgtgatgata gcttttttag ttttgttagt aaaaccagtg taacgtccaa cacgtttagc
    62161 ttttggtttt acgttgattg tgttaacatt ggcaacttta acaccttcga aagcagcttc
    62221 aacagcttgc ttgatcaaaa gtttgtgtgc acgagtgtca acttcaaata catatttccc
    62281 tgcttcaagt tgagccattg agctttcagt gatgacaggt tttttgataa catcatacaa
    62341 attcattatg caagaacctc ctcgatttta gagatagctg cttgtgtgac aagaagtttg
    62401 tcgctatttg cgatgtcaag aacacttgca gttgtagcag ttgcaacttt cacgtttgga
    62461 aggttacgag ctgaaagagc tgcgaattca tttccttctt caaggataac aagaacttta
    62521 gaatcgatgc tcaatgctgc aagaactttt gcaaattcag cagtttttgg agctgtaaat
    62581 gaaagagcgt ctacagctac gaatttgttt tcagcaactt tttcagagta aactgattta
    62641 agagctaggc gacgaacttt ttgtggaagt ttgtagccgt atgaacgtgg agttggtccg
    62701 aagacaacac caccaccacg ccattgtggt gagcggatag aaccttgacg agcacgtcca
    62761 gttccttttt gacgccatgg tttgcgtcca ccacctgata ctgcagagcg gtttttaaca
    62821 gcgtgtgttc cttgacgaag gcttgcgcgt tggctgatga ttacatcaaa cacaactgat
    62881 tcatttggtt cgataccaaa tactgcatcg ctaagaacaa cttggccagc ttctttacca
    62941 gtttggtcaa ataatgttac gtttgccatt gtgactgatt tcccctttct ttattattta
    63001 ccagctttaa ctgctgattt gatagtgata agagatttct tagcacctgg tacgttacct
    63061 ttgataagga taacgttctt ttctggaaca acttgtacaa cttcaaggtt ttgaattgtt
    63121 acgcggtcgc cacccatacg tcctgcaagg tttttacctt tgaatacgcg gttaggtgca
    63181 acaggcccca tagaacctgg acgacggtgg taacgagaac cgtgagccat tggtccacgt
    63241 gattgtccgt ggcgtttgat aacaccttgg aaacctttac ctttagaagt acccgttacg
    63301 tcaacaacat ctccagctgc gaatgtttca actgtgattt cagcgccaac ttccaagcct
    63361 tcaacgtttt tgaattcacg aatgaagcgc ttaggagccg tgttagcttt cgctacatgt
    63421 cctttagcag gtttgttgct caatacttcg cgtttgtcat cgaaaccaac ttggatagcg
    63481 ttgtatccgt ctgtttcaac agttttaact tgaagaacaa cgtttggagt tgcttcaata
    63541 actgttacag ggatcaattc gccagcttca gtgaagattt gagtcattcc cacttttttc
    63601 cctaagattc cttttgtcat gagaaaatag ttccttttct atatttttta ttcaaaaagt
    63661 ttttaacgag cgttttttat gctcaagtct aagatacaaa ggacgtcaaa ctcaacgtga
    63721 aaataggaaa ctgacgcagt gtctagcaga cactaggaag tttatctttt tcacaccgag
    63781 tttagcccgt gttcaattag attgaaacac cagcctctgc tcttttatat tttagattaa
    63841 agtttgattt ctacgtttac accacttgga agatccaatt tcatcaaggc atcaactgtt
    63901 ttttgagttg ggttaacgat atcgatcaaa cgtttgtgtg tacgcatttc aaattgttcg
    63961 cgagagtctt tgtatttgtg agtcgcacga atgattgtgt agaggctacg ttcagttgga
    64021 agtgggattg gacccgcaac ttgtgcacct gtacgagtag ctgattctac gatttttgca
    64081 gccgctgtgt caagcgtacg gtgttcgtaa gctttcaaac ggatacggat ttttttgttt
    64141 gccatctttt tctccttttc gtctatttaa gataataggc tagctccaca agaaaaccga
    64201 cgcggtgttg cgtggcaatg caaccgagcg tgtcgcaacc tcttgcatca aaactaaggc
    64261 tgtaatttac agcaccataa tagaataaca caaagcccct gcgattgcaa gggatttgtt
    64321 gctgtttttt cgtttttttg ggatgaaact gttttcctac tttttctttc taaaattagg
    64381 gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca aatttatctt
    64441 ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat cgcagatact
    64501 gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt ctcacagtcg
    64561 tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa cagatggttt
    64621 tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc aaaattggtt
    64681 tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag acatccatac
    64741 ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc actggcagac
    64801 tggctgtcac cttttgattc ggcgcgtcct tgggtactac cagatggcgt cctgaggtga
    64861 tataaggatc tgtctctagc aaatttactg tagtagaatc taaagcttgg tacaattcct
    64921 gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc ctgactttcc
    64981 ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt ctctcttcac
    65041 ctgttcatag ctttcttttc cgtcattgag cttgtcccaa atcactactt gcccactttt
    65101 gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact ggagcataag
    65161 atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg acaagagttc
    65221 cagtttatct ggagtttcca acatcatttc ttcccaagtg tagccggtcc aggaccaaat
    65281 gtccttgtct ggcaattcct ttcggatgcg tttaactaga ggcaagagaa tgccagtatt
    65341 gagaaaaggc tcccctccca gcaaagtcaa gccttgaaca tagggttggg caaggtctgc
    65401 cataatctgc tcttctaatt ctgctgtata gggaatgcca gcattaaaag accaagtcgc
    65461 aacattataa catccctcgc agtgaaacat acagcctgat acatagagag agttacgcac
    65521 gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt gactaagttc
    65581 ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc caataacgct
    65641 cgactccatt gtgagcatcc tcaaatattc caccatttgc tagaatgact gctctgctag
    65701 caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc ttagcaactt
    65761 gcaagccctg acggagagtc tcttttgcat aacccttgcc tttttcagat ggacgaatgg
    65821 agtagccaat gtggccagca taattcagta acctctcatt cagtctcaat cgcagattca
    65881 aaaatcttag agcacaacct gattcaccaa acaatacgaa ctgtatcgat ggaacgcgat
    65941 tttcaggcaa gtttattccc atctcttttt gaatatttgt ttccaaccac tcttcataca
    66001 caaagttctc tgtatcccaa aatcctccat catgggctga ttggctcttt tcaaactctg
    66061 tcatcatatc taaaacagct ttctttatct gctaatcttg gtctgcgtaa ttccatcctt
    66121 acctcccact atgagaaaag cgagagctgg ctctcacttt tattttttct tgttcttgtt
    66181 taaaaattgt tctctgaagc taagcaagcg ttctttctta ccagctccac ctttagagtg
    66241 tttctcgtga taacgggtca cttgtgcgcg ccccttatcg tctagttgat attttcccat
    66301 ttcatttctt tctaatttgt tacttgatgc ccagctattt taatcgttga accattcata
    66361 tgtttgacac gcgcagcgat ttccttgtga cgcccgttga ccatcggtct tgcttgagga
    66421 ttacctaggt agccacaagt tcgcttcacc acatctactg ttttagggtc gctattgcca
    66481 cagtttggac aagcaaaccc tctctcagtt ggttcaaaat ccccttcaaa gtcacacttg
    66541 tagcaacggt caatcggagt attggtgcct agatagccta cacggtcata agcataatcc
    66601 cagacagctt ccaaggcctt tggattttgc tgaaggactg gatactcaca ataatggatg
    66661 aaaccacctg acgcacctgc ttctggatag actttctcaa agtccaattt ttcaaacggt
    66721 gttggatttt tacgaacatc gtagtggaaa gagttggtgt agtattcctt gtctgtgata
    66781 tcaggaatag agccaaactt gtctatatct agtcggcaga aacggtctgt caaactttcg
    66841 gatggtgttg agtagataga gaaatggtag ccatattggt ctgaccactc ttctacacgg
    66901 cgtttcatat cgtgaatgat gtctagcgtg aattccttag catctggatt actttcccag
    66961 ctgttaccaa agaaaactgt cgctacttca tacaagccga tatagcccag cgaaacggtt
    67021 gcccgacgat tcttaaagag ctggtcaaca ctttcttctt tacctagacg atggccaaaa
    67081 gcaccgtact gataaagaat aggagcattc gctggtgtcg cctctttagt gcgttcgaca
    67141 cggtaaacaa gagcatcttc tgcgatattc attcgctcgt tgaagatttc ccagaactta
    67201 ttcatatcac cttcagactc aagagcaata cgaggcagat taaccgtcac aacacccaga
    67261 ttcatgcgac ctgaattgac ttctacacca ttttcatcct tccatccttg gaggaaagaa
    67321 cggcaaccca taggcacctt gaaggatcct gtcaagtcaa caatcttatc gtaagataaa
    67381 acatctggat acatccgttt ggttgcacac tcaagagcca actgcttgat gtcgtagttg
    67441 ggagttcctt cctctaaatt aaggcctctt ttcagagtga aaataagttt aggaaagata
    67501 gccgtacggt gttctgaacc aagacccttg atgcgaatgt ttaaaatagc tttttgaatt
    67561 tctcgttcaa aacgactggt tcccagacca aaacctagcg aagtaaaagg tgtttgtcca
    67621 tttgaagtga agagagtatt gatttcatac tcaagagatt gcatggcatc gtagatgtcc
    67681 ttttgcgttt tcttccaagc gtaatcttcc cgtttttcag gcaataccca ctcttctgca
    67741 tctttgagat gtttttgata gttcttctct gcataaggcg ccaaaatttc atcgatacgg
    67801 tcagctgaac agccaccgta ctggctagaa gcaacgttgg caatgatttg agaaatctgt
    67861 gctgtcgcag tttggataga cttgggactc tctacctctg catttccaat cttaaaacca
    67921 ttttccaaca tacccttaaa atcaatcaaa cagcagttgg tcataggggt atagggactg
    67981 tagtccaaat cgtgatagtg gatatccccc ttttggtggg cattggctac gtgcttagga
    68041 agcatttgca gtccgattga tttcccaaca atccctgctg tcaaatcacg ctgagtgtta
    68101 aagacatcac tgtctttatt agcattttca ttgacaactg tctggtcttt gttgagaagt
    68161 ttatgaatac taaagttgat atccgtcgct tttgagcgct caaaatccct ctgtgtccga
    68221 taagtaatat actcctcagc cagcgcatat tctttggctt caaggagttc atgttctacg
    68281 atattttgaa tttcgtaaat cttaattccc tgtggaaagc gactatgaat ttctgtaata
    68341 attcgctcag tcagatcatc gaggcgtttt tcaaccaggg gtgtcacatc cataaccttg
    68401 tcagccgcct tgtggagagc cttgtcaatc ttgtccacat caaatacaac acgtctccca
    68461 tctcgtttct cgacgaagag agttggcaaa attgtaattt tttcttctag tgcaatcata
    68521 tgcatgctct tttctaaaat gttctttcta aaaagtatta taccactcta aaaagaaaaa
    68581 tcaatatctt gtgttaaaaa tcctaaaatt tttaaaaata cacaagatat tgatttggtt
    68641 atttaatttt atagacttta aactctgagt aatcagtctt tacttgttgg taattttctt
    68701 ttaagagtgt ttccacttca gaccagacta ccaccttgtc atttaccaca atcaccttag
    68761 gttgtttttc tttcaagtca ttaagtaact tattacgatt ttcctcagtt gctgtatagt
    68821 gcaacgggga caaaatcgcc gatggcgaca agcgctcact cttacgataa agagtcgcag
    68881 tatcatccca tgcatagata gtatcttccg tatttgtctc ctcttttacc aaatcagcaa
    68941 gacgattacg ttcttgataa ggtactggat aaaggacaaa cttcatcaaa aaaggaacag
    69001 acaaaagata gacaaaccca aaaactagca gatatagatt tcctttgaag aaacgactcc
    69061 ataggctaac tggcgtttct cttcggcttc ttctagcact acgccccctc tgttgactct
    69121 taatattggt taccaataaa agtaggaaaa cagggaagac gaccatcaaa taagaagcgt
    69181 gcagaggctc ttgtgaaaag aaaagtaaaa tcaaacctaa aattaccaca agacttgcag
    69241 gaaccgaaat gacgtatagt ttaaagggtt tggtttgaaa gagacctaaa aagatacaaa
    69301 ccacaaatcc caaaccaagg gacaacaagc cataaaaaaa catattctct aaaattttag
    69361 aagtaaaatc aaagcgaata ctgtcaatag gataacgaat accactaatc gcatccccaa
    69421 aacttcctgt tgcagcacta tagtaggcag ttggataaaa gacaagtgaa aaacctaaag
    69481 ccactgcaag aaactgataa aacccatgcg caaagcgtct atgcccaagg ttaaagacca
    69541 acaagcctaa actcactaca gcaataaaca ggagcgatga taagggagca aagaaaaatc
    69601 cgcctgccaa agctagccca atccgtacaa atcccttatc atggcttgga ttgcttaggt
    69661 aagccgcaac taaactaaag gctgcgaata agaaaggaag cgctaaaaga gtcgcatagc
    69721 ctccaccaaa agcaagacct gtaactagca tgtaaaaaat agtcaccaga tgtccagctt
    69781 ggtctccttg ctctgtcaag gtgtccgctg atctaaaaag gaaaaatcct cctgctacca
    69841 aggctaacca ctcaaagatg gcaaagaaaa atcctccctg actcacgtaa gtcagcaaat
    69901 aataaagcaa accttgactt ccataatagt cgctgtaaat cttccctgtc tgatgaagcg
    69961 cccaacctgc ataaaaatcc tgcacttctt gtgcactcat taagtcgagt aatagcggta
    70021 ctcctagagt tatccccgtt acaagcgtac tccatagtaa aattttcacc aaaggaagac
    70081 gacttgattc acgatgatgc gattcttgtt cgatttggta ttctagaggt tcacgattct
    70141 ccttatgaac ttcttctact ctaccataca cactcatatc gtttctcctg ttcaatttat
    70201 ctgtcttagt atatcaaaaa gtcctaggat tgtcagcttg cgatggctgt ttgagtgatt
    70261 ttttgcatag tttcacaaag gtttcaattt cccgaaagcg gtgtaaatgt gtctgtttga
    70321 actcaatcat atcattcact tcttccttag ttagcatgaa ttcccctcct ctttctttct
    70381 attcgtaaaa gacaagaaaa ataggtctgg tttgtatcct aagttctaga tttcttataa
    70441 gataggggcg aatagctggg cgatttcttt tacaagcttt tgataccagc tcgttttgat
    70501 agaatgagga tagacttcct gagaatctgc aaatatattt cgaaaatctc gggcgatttc
    70561 ccttatagaa ggagttttat agagtaagac tgcattttca taatggtgta ccaagctccg
    70621 gtagtcgaga ttgattgtcc ccaccaccgc aaaatcttcg tctaccaaca tctgcttact
    70681 atgaataaaa cctggactat actcataaat ccgaacccca gcagaaagaa ggtcgggata
    70741 agctcctctc gtgactaact gaatgaactt cttatctggt atgtaagggg taataattcg
    70801 aacatcgacc cctctcatag ctgcattttt gattgtctct gttaaatcat aatctataat
    70861 caaataaggt gtcgtaatat agaccgattc cgttgcttga ttgattaaac tctgataaac
    70921 ttttttccct acctgcgctc gaaaaattgg cttgggtcca cttccgtatg gaatggttaa
    70981 accgtcactc gggatagaat gattttctaa atgatattga tcaaaatcac taatttctcc
    71041 tcgattaatg taccaagtgg tcaaaaataa gcgtgtcagg gcttttactg ctagtccgtc
    71101 taagcgaatt ccactatcct tccaataacc aaatctctcg acgtggttaa tgtactcatc
    71161 tgccagattg accccaccag tataggctat ctgaccatca acaatcaata tttttctatg
    71221 atctctgtta ttataagcca ctgtcaaacg aggaataact ttattgaatt tatgggcctc
    71281 gatgcccagc tgacgaagtc gatgtgcata atctcctgtt aaagtagcca tacagccgat
    71341 atcatcatag agcatcttaa cctctacacc ctgagctacc ttttgctcta gtatatctag
    71401 tatgcgattc cacatcaaac cttcttctat aatgtaatat tccaagaaaa taaatttctc
    71461 agccttttta agatcttcta ccatcttttt ccacatagct tctccgttag gaaaaaatgt
    71521 agaggcagtt tgatcataga tgtcagcatt ggtatccata ctcaataagg acttgatgac
    71581 tccataagct gccttgtcac tttcttttaa tttctctttt agtagctggc tatttgcttc
    71641 ttggaaatgc atagagccta gcttcttcag ttgtttgatt tcttttttgg acaatcgcct
    71701 ttcaccaaac atcagataga gcaagggacc aaatactggc acaaaggcta ctaacaacca
    71761 ggttacctta ttctcaggag tcgtattacg gttgactatc gaaatgattg tgatgatact
    71821 cagtagaatg aggacagtaa tccataaaat gggagccatg cgtcctaaat aaagaaagag
    71881 accaaaaaca agacaaagtt caagtaacat aatcgaaaga ctaaagccat acttggacat
    71941 caataattga aatttcctat atttcatatc ccctccttga tagtttgaat gctaaaaaca
    72001 agtaattgat actagtataa cgcaggtatt cggtagaagg caagtattta tgattatttt
    72061 ctaggtaaaa gtaaaaaggc tgaaaaatcc agccctttct acttgcatag tcttatttag
    72121 ttaaaacgat ttggtccgat gggtctctat ccatatcatc tacgacgatt tgattaccgt
    72181 ttacagtgta aattttgaca tcatcgccaa taatcatgcg ttgatttgct gaatcaaatg
    72241 taacctgttt gactttctga tccccgtcag attcgagctc agtccatgta ccagtcgttc
    72301 cagttaccac taaagtgata cggtctccgt catcctgacc agtataagtc ccatcaatat
    72361 cggtcggttg agcaacaggt tggttttgta ctggagccgc ttgattttgg ttacctcctg
    72421 catttgcagt attggtattc tgttgagcag gttgttgagc aggctgttga acctgttgag
    72481 ctctttgtga acaagctact aagagactaa aacttgctag agaagcaaga gaaagtgtga
    72541 atctttttaa tttcatgatg aatttccttt ctgctaccaa tttagagaaa ttttctctaa
    72601 ccagcaattt ccctagtata acaagttcaa acaagggggt caatttatct gctcacggtc
    72661 cagcaggtag ccccgtactt ctgagataaa atagagagac cctgtaacga acagcaaatc
    72721 ctgagcatct gctctttctt caaaatcgct gataaattct cggtaagaag aaactatatc
    72781 gtaacctgtc acatcccttt cgtccaaaga cccttgatag tcaaaaccag tcatcttgag
    72841 ttccacttga ggtaaatttt cagtcagata acccaacatc ccttgataat ccttccgttt
    72901 caaggatcca aagaggattt gaggacgata accttcctgc tctttttctt taataaactc
    72961 aaccaagcga gtcaaggcag ggaggttatg agcaccatcc aagtaaatct gtgggcgaat
    73021 acgctccaag cgaccagccc aatgggtctg ttccaaggcc tttcttacag cctgttcatc
    73081 aacagcttcc tttccttctc ccataaaaag aagaaaagtt tgcaacgcca aggctgcatt
    73141 ctcctgctga tagactcctt ctaagcctat gttcagctgt gaaagattta gtaaagagct
    73201 tgaaaaatca ccattcagca ttaaaaaatc ttgacctgcc tgataaaggt taacagctaa
    73261 agattcggct tttttctgac agacaagcct agcttctgga tgcaatttcg caatcactgc
    73321 cttcttacca gccttgaaaa taccagcttt ctgctctgca attgcttcta gactatcacc
    73381 caaggtttct tgatggtcaa gcccaatgga ggtgatgaca gcaagctctc cagttaccac
    73441 attggtcgtg tcaagtaagc caccaattcc cacttctaat aaaaccaaat ccacctcttg
    73501 ctccctaaaa taaagaaaag caaccaaggt cagcaattca aaaaaggaca actggtcagg
    73561 agtttgcaga agcgttttct ccatctcctt gacctgatca gccaaacgga taaagtctgc
    73621 gtctgctata ggttgcccat taatgcagat tcggtcattg atagagacga tatgagggga
    73681 ggtaaaggtc gcaacttttt tgccatgccc cataaataat tccctcataa aagcaatggt
    73741 agatcctttc ccattagtcc ctgttacgtg gataataggg taagactgct caggatttcc
    73801 taacaaatcc accgcttgct gcattcggcc caaacctgat cgaaaattca aaccaatccg
    73861 actatggagc cattcttcta cttcaaacat acacatctcc ttgacaaaag tccaatcaat
    73921 tatcgcatta aagtatggtt actaataaaa acaaggccag gattttcgtc ccgacctctt
    73981 acctggttag ctaataacta gctactatga atgtgaatat gggctaaaaa catccactag
    74041 atgttccaac tcttctcaat ttctaagagt tggggtaaaa atgttcactg gacgttccaa
    74101 ctcttcccca tttctggagt tgggctgata cagtctccca gacttaccag ctctatctta
    74161 tttaaaggag ctgggctaaa aacgtccccc cgaacctacc agttctctct tatttaaagg
    74221 aactgggcta aaaacatcca ctggacgttc caactcttcc ccatttctgg gagttgggct
    74281 gatacagtct cccagactgt atcactcctc cataaagctg ttgaagactt cttcaatcat
    74341 gttccattcg tcttctgagt cttctgggat tggttgcaat tcgccttctg ttccatcttc
    74401 gttttcgatg aatgagtaag cttggatttc aacttgtccg tcttcgtctt cttctgcgtt
    74461 aactggtact agaagaacat agtttttacc aaattcttct tttccatcaa ttgtcaaaag
    74521 gatttcaaac aaggtttcat ttccttcctc atctactagt gtgattagtt cacgttcttc
    74581 gtggtcgtgg ttatgatcgt gtgacatagc ctctccttta tattaaaatt ttctatctaa
    74641 ataattttgt aaaatcagct gagctgctaa cttatcaatg actttcttgc gcttattgcg
    74701 actgatatct gcttgttcaa tcaacatgcg ctcagcagcc actgttgtca agcgttcatc
    74761 ctgatagtct actggtaaac caaaaaactc ttctagcttt gctccgtagg cttgactagc
    74821 ttctacgcgc ggtccacttg tattgttcat gtttttaggc aagcccacta caaatcgttc
    74881 caccttgtaa gtatcaacca attccttaac gcggtcaaaa ccaaatttgc cttgttcttc
    74941 atttatctgg atgatttcaa gcccttgagc tgtaaaacca agcggatcgc taatcgccac
    75001 ccctaccgtt tttgaaccga cgtccaatcc cataattctc ataggttata gatcgactcc
    75061 ttgtcctttg aggtagtagc gaaccaattc ctcaacgatt tcatcacgct catacttacg
    75121 gatttgattt cgtgcattat tataacgagg aacgtaggca gggtctccac tcaatacgta
    75181 acctacgatt tggttaattg ggttgtaacc cttatcgttc aacgaagcat aaacatctgt
    75241 caaagtttcg ctaatttctt ttttattgga atcgtccaat ttaaaacgta ctgtttcttc
    75301 agtaaatccc attctaacac cctctttcct tagaatagta ccattatagc ataattcctt
    75361 accttctaca attcaggcag tctatttatt tggattttct attgttctgt cgcgccattt
    75421 gccaatctat ctgaaatata tttgcttggt tcatttttca aaagattttc caaaccaata
    75481 ttcttcagat gttccaactg ggaagccttc ttgacatcca gaacttgaaa atcaaaacta
    75541 gtcgttgttt gaagttccgt tgcgctcaat agttttgttt caagtttgaa acctgccaat
    75601 ttacgagctt caatgataga cttatccttc tcctccgctt caagaagagc tttttgagtt
    75661 tcctccactc catgttggtc aatataagtc ttcaactcat cagagactgg acgtttttgt
    75721 tggatagcta gactcaaaaa agtcttgtct ttgtaagtaa ttgtttgtgt ctgctggcta
    75781 ccatcatctg acttgggcaa gaccaaagtc ttagttacaa ctgtattctt ctcagcattt
    75841 tcaataactg gcaatgccga ctgaagcgta tctttttctg tttttgtagc tggtccagtt
    75901 tcttttttct gtccgcaacc aaccaggaca aaaaggaaag ctagactaac aagaactatt
    75961 tttttcattt ctttcttctt tctttttgaa attaaaatag aataagactg ggaagtgctc
    76021 ccagccttga tgtttataga gctgcacgca aacgtgcttc tgcattttct acattacgga
    76081 cagagcgtgg taggaaggca cgaatatcgt cttccttgta gccaacttgc aggcgttttt
    76141 catctacaag gattgggctc tttaaaattc tcggtgtttc cataatcaga ttgagaactt
    76201 cattgacact caaatcttca atatccactc caagggcttt ggcatagcga tttttagacg
    76261 aaacgatgct ggctattccg ttatctgttt tggttagaat atccagtaat tcttctctcg
    76321 taattccttc tttaccaagg ttttgttctt tataacttaa ctggtgggca ttgagccagg
    76381 tttttgcttt tttacagcta gtacaacttg agactgtata aattttaatc atgtacctac
    76441 ccctttcgct acatgttact atcagtttag tctattatac cataaaaaac atccgacttg
    76501 cgacctattt ttaatttttt ttgacttttt tcgtcatttt cgtacttttt tcttgacaaa
    76561 caactaaatg actatcaact cttttggagc tagggtcaat aattcacaac ctgtctctgt
    76621 aatcaggata tcatcctcga tacgaacgcc atatttgcct tcgatataga tacctggttc
    76681 atcggtcaag gccatacctg tcttaatagt ttctgtagaa gtctggctaa agtagggttc
    76741 ctcatggata tccagaccaa taccgtggcc aatgccgtga gtaaagtagt cgccataacc
    76801 tgcctcaatg ataatatcac gagggatttt gtcaaagtca cggaaaccta agcctgcctt
    76861 agcttggtca atcaaggctt ggttagcttt tagaaccgta ttgtaaatct ctgcctgctc
    76921 atcgctaaca tgccctagat agatagtccg ggtcatatca ctgacatagt ggtcatagag
    76981 acagccgaag tccatggtaa tggcttctcc caactccact ggtttgtgca ttggatgggc
    77041 atggggttta gaagaattga taccgctagc taggatcgta tcaaaagata agccagatgc
    77101 tcccaactca cgcatgcgga agtcaaggaa gttggcaatc tcaatttcag tttttcctgg
    77161 tttgataaag tcaagcgcat cgcggaaagc ttggtctgag atagaacaag ccttgcgaat
    77221 cgctgcaatc tctgcctcat ccttaatcat acgaagacct tccacaaact gagtttgtgg
    77281 aagcaagttc aaacctgcaa aagctgcctg catacggtgg taataagaca ctgaaatctc
    77341 atcttcaaaa ccgatacgag tcaagcccat gtccttaaca attcctgcaa tgacagccaa
    77401 ttcatcacga tcagccacaa tctcaaaacc actggtttct tgcttagctg cgatgatata
    77461 gcgagagtct gtcactaaga cctgacggtc acgactgata aagactgttc cgtttgagcc
    77521 ccaaaaacca gtcaaataat agacgttttt aagattgttg atgatgatac catctagttc
    77581 tttttcttgc attttagcta gaaatgcttg tacgcgttta ttcatgatgt aactttcctt
    77641 tcaaatagtg tcctgtatag ctggcttcgt tggcagctac ttcttctgga gttcctgtta
    77701 cgatgatggt tccaccaccg acaccgccct caggtcccaa gtcaatgata tggtctgccg
    77761 tcttgataac atccagattg tgctcgatga cgaggactgt attgccggcg tctacaaagc
    77821 gagctaaaac cttgagcagg cgagcaatgt cctctgtatg aagccctgtc gtcggctcat
    77881 ccagaatgta gaaagatttt cctgtcgagc gtttgtggag ttcgctagct aacttcatac
    77941 gttgggcttc tcccccagaa agggtggtag ctggctgtcc caaggtcaca tagcctagac
    78001 ctacatcctt gatggtctgg agtttgcgtt gaattttcgg aatgtgttgg aaaaattcta
    78061 ccgcatcgtt gaccgtcata tccaagacct gcgaaatatt cttttccttg tagtgaactt
    78121 ctagggtttc actgttatag cgggttccgt ggcaaacttc acaagccaca taaacatctg
    78181 gcaagaagtg catctcaatc ttgataatcc cgtcacctga gcaagcttca cagcgacctc
    78241 ccttgacgtt gaaactgaag cgccccttct tgtagcctcg aatcttggct tcatttgtct
    78301 gagcaaaaag gtcacgtata tcgtcaaaaa ctcctgtata ggtagctggg ttagacctcg
    78361 gcgtccgtcc gatagggctc tggtcaatat caatcaaacg gtcgacatgc tcaatccctg
    78421 taatagtctt aaacttacca ggtttgtctg aattacggtt gagcttctgg gcaatggctt
    78481 ttttgagaat gctgttgatt agagtcgatt tccctgaacc cgacacacct gtcactgcga
    78541 taaattttcc tagtggaaag cgagccgtga cattttgcaa gttgttctca cgcgctccta
    78601 tcacttcaat aaaacgacca tttccgacac ggcgctcttc tggtactggg atgacacgtt
    78661 tgcctgacaa gtactgacct gtgatagact tgctgttgcg agccacttgc ttaggtgtac
    78721 ctgctgcaac aatctcacca ccaaaaacac cggcaccagg accaacgtca atcagataat
    78781 cagcttcacg catggtatct tcgtcgtgtt ccaccacgat aagagtattg cccaagtcac
    78841 gcatcttttt cagactggca atcaggcggt cattgtccct ctggtgaaga ccgattgacg
    78901 gctcgtctag gatatagagg acgcctgata ggttggaacc aatctgggtt gccaaacgaa
    78961 tgcgctgact ttccccacct gaaagggttc ctgctgaacg tgacagggtt agatagttaa
    79021 gacccacatt attaaggaag gtcaaacgat ccttgatttc cttgagaatg ggacgagcaa
    79081 tgatggcttc attttcagac aaagttaact ggctcaccaa gtccaagtgg tcagcgatag
    79141 acaggtctga gatttctcca atatgtggcc cttgctggcc gcccacacgg acagacaagg
    79201 cctggtcatt gagacgatag ccttgacagg ttccgcaggt cagctcattc atgtagagac
    79261 gcatctgagt gcgagtgtaa tcgctattgg tttcatggta acgacgtttg atattagtga
    79321 cgactccctc aaacggaatg tcgatatcgc gcacgccacc aaattcattc tcatagtgga
    79381 aatggaattc cttaccatct gacccataga gaatcaagtt cttatcttct tctgacaggt
    79441 cctcaaaagg cttatccata gccactccaa agactttcat ggcctgctct aacatgtttg
    79501 gatagtagtt ggatgagata ggattccaag gtgctagcgc tccttcacgt aaggttttgc
    79561 tggcatctgg cactaccaaa tcagtatcca cctccagctt aatccccaag ccgtcacact
    79621 cactacaaga gccaaaggga gcattgaaag agaagagacg aggctctaac tctgggacag
    79681 taaatccaca aactggacag gcataatgct cagagaagag caactccgaa tcgtccatgg
    79741 tgtcgataat cacataacct tctgcgatac gaagggcagc ttcaatggaa tcaaagagac
    79801 ggctacgaat gccctccttg ataacaatac ggtcaaccac gacatcgata ttgtgttgct
    79861 tgctcttaga caactctggc acttcggtca catcatagac ttccccatcc acacggacac
    79921 gaacatatcc gtctttctga accttctcga taacattctt atgttggcct tttttcttgc
    79981 ggatgacagg agccaagatc tgcaagcgct ggcgttcagg taactccaaa accttatcaa
    80041 cgatttgctc cacagaagaa gcattgatag ctccatgtcc gttgatacag taaggcgtcc
    80101 ccacacgtgc gtagaggaga cgcagatagt cattgatttc agtcgtcgtt cccaccgtcg
    80161 agcgaggatt tttactagtc gttttctggt cgatggaaat agctgggctg agaccatcaa
    80221 tggcatctac atctggtttt tccatatttc ccaagaactg acgagcgtag gcggacaaac
    80281 tctctacata gcgacgttgt ccctccgcat agagggtatc aaaagccaga ctggacttcc
    80341 ctgaacctga caagccagtc acgacaacca acttgtctcg cggaatctcc acatcaatat
    80401 tttttaaatt atgggcacgc gccccatgaa tgacaatttt atcttgcatc tttgttcttt
    80461 ctagtccatt attgcttacc attataccaa aaaaagtgag attctattac ccaaaaggcc
    80521 gattttgtag tataataaaa aacttcttat tttatgtttc cttagggctt cctaaccctt
    80581 atatcacgcg ctttttaaca aaaaacacta atattacttt ttactacttg ctcccccaaa
    80641 gtacgcaaaa aggggagcaa aaaagcccca caaaagggct aagatttgac gagttcagca
    80701 ggcaagaaac tagcgtagtc atcagctacg cttttttagt tgtttttgct tatctgatag
    80761 gtttattata ccaaaaaagg gagtgtgtga catctcggtc taactctccc taatcggcta
    80821 gactgtgcaa gcctccagct gtgaatatat tataccatgt tcatcacgcg tattggttgt
    80881 tttatctatc gaaaaggtga gatagataaa agcgcgtggt tatcgatttt gttgacctta
    80941 acaagtcctt ttcaagcgaa catcacgcgc aaaactatta tattttacta tttctttgta
    81001 ctatagatct tccttttcta tttcctctct gcttattcta gctaaaagat tataataagg
    81061 gtgtcctgct ggaataacag ggggattttt agtaaattct tcttgtgtta aggtggtttc
    81121 tttgtctaat attgtaccgt ctgatagttt ggtaccttta gggacaatat gggatattgt
    81181 tgggttccat ttttctttaa cttttgccat gttaaatact cctttatggt aaaaatagag
    81241 gcgtcccacc tcctaccgcg gaatgaactg tttcaagggg agatggaaaa cctctattcg
    81301 ttaatttaat tatagcctaa ataactaatt gacgcaataa tgttagaggc atatcctttg
    81361 gggtggtcga aacagtaaaa aggaactgac ttaggcgccg acctaaaata agccattggg
    81421 tgccaaacca gttcctttat ttacttaagt atacaacatt tttacaaaaa aagcacgttt
    81481 gattgtgtta gtttcttgct tactgaactc ttcaatttaa gtcccctttt tgttaccctt
    81541 tatgttttct cagcttattt gaatttaata gtttgtgaag aaattaagtt agatttagag
    81601 caggcttagg cctgtttctc tgtatctaac caaaatctta ccgttcttca atagctcact
    81661 agctttgttg ttccaataag tagctagttt tctagtctct tatcctttct tgaaaaactc
    81721 cgcattgtga tttataatta agttaaggta aaggtggtct aacgcccatg aagcagcttg
    81781 ctgtggaggc ggtgggtcac ctttattttt ttatctcaca aaagccccta gatttgtttc
    81841 tgagggcttg tagtttatcc gtggtgattt agttatccag tccaaaacaa aacgaataag
    81901 gggcgaatat aaagcctagt gccccctata cgcactaggc tctgtggtaa ggttaaatca
    81961 attcccattt accatacatg ccaagtgttc tatagctgcc ttctttgccc gatatatcga
    82021 agctttagat ttacctattt cctcagcaac tccccaaata tcgagatcat tcaagtaaaa
    82081 aagtctcaga acagagcgct caagcggatt ggctagctta tcgatcagcc cagatatttc
    82141 cattctttcc tcagtaatgc gctcaatcct ctggagcgta tcctctttta gcttcagaac
    82201 acttataaaa ttgttctctg tcttgttctc tctgcttgtc tgcaccctgc tatggcttag
    82261 tgttggcttt tggataatgc caccttccag ggcttccaat tccaaatata agcctttgat
    82321 ctccttattt atccacttaa cgccctctag tttttctttt acctgctcgg gtgtcatgcc
    82381 tcggcctcct ttgtgatata atagttttag ggaataattc ataaaggagt cagccgtgtg
    82441 ctggcttttt ttcattttct ctagcttcgc tctaggttca agtccattct acgtaccatt
    82501 tgataagcaa ttaaggcaag ttattccttt gctgatctgc ttatcatttg gtaagcaaca
    82561 aatccaaaat aacagacttt taaattgctc ttatctcctt atcatttggt aggaaaataa
    82621 ggagagttat tttagttctt atttccctgt cattttgtaa ggagaaaaac gaaaataaag
    82681 agcttttaaa ttcgtcttaa ctccctatcg ttttgtaagc aattaagaag gcttattgtc
    82741 gtccttatct gcctatcatt ctgcaaggag taaatcggaa ataagagggg taaaaactcc
    82801 gcttatctgc ttgtcgtttc tccgggagtt aaggagggtt attatttctc ttatctgctt
    82861 gataaatgat aggggatata tccactttct cggcgttcgc tcggagttca acacacataa
    82921 ccctgccatt tgtcaggcat atttactgcc actacctaag caaaatctca ccttttctaa
    82981 ccctcggtaa acctctctac cttgtgctaa ccttggggct ttcaaatacg caacctttac
    83041 aaaaccttta cattttttgc tcttacctca ccaaaacctc accattggaa aacttcgata
    83101 ccttaccaaa accttaccgt tctatggttc taaaaaagta gctatacctt agggtaatct
    83161 tagggtcata tcactagaaa aaaagccctg taccttgcta aaaccttagt attttgaagt
    83221 atgtgacatt agcctaatct tagcctattt ttaatatttt taaatacaca accttgtact
    83281 aaccttgtac tttatatata tgtaacctca cccttacctc accctttttt tggaacgatt
    83341 accgcaccct tttttggaac gctctactta cttaaaccct tgatatatct agctttttta
    83401 acattcaaac cgtctaatat gtagtatttg tttgttttgt aaattgcaca ctactacaaa
    83461 ttatcatgta aaaaacctaa atcgattggg ttacatacta aaaggggatt gctcccctgt
    83521 tttctacttc aaatgctctg tataaacagc aaggccttta tattcgccct ctacgtccaa
    83581 cttttggatt aggctaatac tttcatcgcc cagcatttcc aacgtaccaa aagcggtcat
    83641 tgagtccata gggataggct tatcagaaag caagcgatca gcatagtcta acagttccag
    83701 ctcgtagtct gttactttct ccagcaaact ctcaaagtcc tctgactctt tgagttggag
    83761 cacgcgctcc cgtttataac gttcttcaaa tgcttcatcg tccactagtt ggttgtagta
    83821 gtctttaaaa ctgtcacaaa tacgcttgaa ggtcttgttt agtttgtgat cttccacata
    83881 ctcagctaca agcgtccctt tatccttgtg agttattgaa atagatggta cttcataagt
    83941 cccagtcata tatcccagta gcgcgtgtcc tgctaccata gcagtgtcta ggtctttaaa
    84001 ttcgtaagtg aaagtaaatg ttttggcttt atctgaaaat gtttttaatg tcatgttgtt
    84061 tttctccgtt tcttagttta aggtaaatta tgtaatattc gttaatttgt taccttcttt
    84121 agtgattttg ttaccttcta ggtaacatag ttaagcctta cacccccaag ggtttagacc
    84181 cttttgttac catgttacct tcttttgaag tcatagccct tatatataaa aatactattt
    84241 ttccctatat agagagttaa aaacaaggta acaaggtaac attttcccaa aaaagtcagt
    84301 agtatcaagg gtttaacaac gttaccttct ttctaaacaa ggtaacaaga aggtaacatt
    84361 tttgggtaaa aacctagata taccaagggt ttagggcata aaaagaaggt aacattttag
    84421 tctttaacga cagcgtgatt agttttggat agtttggttc tttcaaactc tagcggatct
    84481 agtttgtcat aatcttcaac tttgaccctc gctcttttaa gtttgtaatg attgggtgtt
    84541 aactgttgta agtgtcttat cgtttctttt cctgccccat aaacattggg cttgggtatt
    84601 cccatatctt cagcataatg tttcagcgac ctagttagta taaaaacagg tactacgtcc
    84661 agctcatgcc aacctttttc catgtattca tgcttaaccc atgaaagtaa gtagtcatta
    84721 tcctcctggt attcttctag gagtccttta actgctttag gttcgataaa gtgagtaaat
    84781 ggctcttgat tgatagcttt gtaaagtgca tactctaata cttcatcatt ggccaaaaat
    84841 tcatttttta tccaaggttt ttccttctcc ccgttaaagt cagcattaaa agggacgatc
    84901 ataattctac gataccagcc ttttgtcttg ttgccaccat tggggatata attccctgaa
    84961 aagatattga acaacttgaa agtagcttca aaggctgggc gacctttggg gttgactaga
    85021 acagtgtcgc cactagtaat actcattaaa tcagacggat tttttaagta ttcgtttggg
    85081 gcttcatctc cgatattaca aactttacct accagggttt ctaagttatg cttttcagca
    85141 aactgtgcag gttttaaggc tgatatattg ctttccccta tcaggttgat aaggaagcgc
    85201 tgaaatgttc ccttaccgtt gttaccgtcc ccgtagaaga tagcaaactt atttcgggta
    85261 tggttagggt taatagcttc aaggataatc tgccaaaaca gtgttaccag ttcactatca
    85321 ttacaagcga ttgagtttag ccaatcatca aaagttttgc cctctctatc tgttgggact
    85381 cgtttaggcg cgtggtaggc cgtgcttatc ttacttgtaa ttacatactt aggactaaag
    85441 gggagtagtt ccttagtttc taagttgata atgccgttct gtacgggaat gaggttagca
    85501 ctttctaaag gttttcgtat ctttaccaat gttctaacca ttaacttaat ctgtggccac
    85561 tctctgggtt taattctaac gtcaaaggtc ttacacaaaa gattgaatag atcattacta
    85621 gcggtataga taccctcgtc taaatcgtag atatagagca ggctataatc aggtatattg
    85681 atcttgctga taaaagtaaa tgtgacaatc tcgctcagta ttttagctac tgtgaatgtt
    85741 tggggcatgg ccaccttttc ggtgacgtcc cctgtggtct catttacttt agtttcggta
    85801 tgttctgccc gccattcttc accagcttta aagatacgat tttcaagctc cttcatcgtt
    85861 ctaggagggt gttcttgctc tctgacctcc atgatttcac tttttaggtt tgctaattct
    85921 tctagttcta tggttctaac ctctctttct atattcagcc cgtgctatac tgctaaaagt
    85981 gcggtctagc tcttcaatag gcaatggttc aaccgtcacg ctattggcta tctttgtaag
    86041 ttcataggcg gtctctaggt cacaatcaac ccacttatta aagagtaagc ctacaaagcg
    86101 tgtcaatgct acgttgcgcc ctccctcgtc tccaaagccg ttgaaaagcg tgtcaatgat
    86161 cctcatggtc atagatttct gaccgcttgg ccttggagtg tatggaagac ttgtagcatt
    86221 ctgtttgact ggttcagccg ttgtctgtgg tactggataa tcaagtccat gctccacaat
    86281 cttttgataa cttgctaggt cgcctgttgt tactggtagc ccttgaagtt gtgaccatgt
    86341 aaggctggcc atatcaaagg gtagtccaat cttgtcagca atctctttca ctacctgctt
    86401 ataggttgcc tcattcatca cgttgtcagg cttcactaca aggcgaaaac ggggcttttc
    86461 taagttatgt ttaatagtcg ggtataaaat atatgagtag ccaaacaagg tgctagaaac
    86521 gtcctttata aagccctcag acgtcccctg tatatcgtca taatcaagga aaatcaaatc
    86581 ccgatagatt agactggagt tgtttcgctt gtaactgcca ttcttttctg gtgtcacttt
    86641 cccactgata cagtaaggcg cttgtgtacg tttaaattct tcaatgtttg ccccttcagg
    86701 gactaccaaa ggcttaaagc gttcaatgta ctggaacggc tcaatcttat caaatggata
    86761 gacaagatta ccctgaaagc ctctagtctc gtaaattgtc atactatcgc ccctttttgc
    86821 gtttcttttt taacttcttc agtagctttt gttcttggaa ctgttccaaa gatctgccac
    86881 ggtgcttata caatttaatg tcatgataat gacctccgcc ttgtgctggg tgtgtgttat
    86941 atctagccat tctccacccc cataaacttc cagatgtccg aaattctata atagattttc
    87001 ctagtatctt ctagtggggg ctggtatcgc cttagccctg ctttttccca tttttggagc
    87061 gtcatatact taatatctaa ctcatccatg acttcctggg ctgagattaa acctgtcagc
    87121 cgtggcttga gtctatcacg cgcttccagg tatctttcca ctacctccag aatgccttgc
    87181 gctaggtctt gctcgctttc tcggcttagg ctaaacatat ccgcccacct ccttcaaggt
    87241 ttctttgtaa ctctctaaat cagcatttaa aaggatagtt aggcgtttct gttcttcctg
    87301 tacttggtta tagaatgcct ttgctccgtc cagtaactcc tctttgttag ctgggataaa
    87361 atatcctcta aatgttccgt gtcgaacccc aacgattgga acgccatagc gcgtgattag
    87421 acggctgata atatcttgca cggttctttc tgccagctta gtgatcaggc tgatttctgc
    87481 ccctgttatg gagttctcag cacctacctt gattagtctc aatactcgtt tgtcattatc
    87541 tgatagactc attcagttcc tccccatacg ttgacccctg caagctggat ataacgccca
    87601 taatcagggt ttaaatcctc gctaggtgtt tctatcgtcc gttggttttc tcgctcaaat
    87661 tgggtgcttt ttttgcggtc tcggtggttt aaataaagca gtaagccaat caataccacc
    87721 ataaagatta ccgattgtgt attggtcaaa tctaactcat tcatgttatg ccctcgcttg
    87781 ataactcttg ataaattcca cttgtttttc atgtttcatc ttcaggtatt cgtctacctc
    87841 ctcagtgctt actttccgat ctacaaaatc cgcaataaac tggaagaggt ttgggcgttt
    87901 cgccttgatt tcagccatta cttcatcaaa ttctgcttgt gtcatgttgt ctaggtctag
    87961 tgtcattgca ttgcctcctc aaacttctct ataagacaac ttttatttac tctctgagtt
    88021 ccatttttag agttaaaaag aatatctttt aaggttatag tagcctctaa atactccttt
    88081 tcagcatgtt ctatatacgc ctgttgctct gcttcgttgt caaaaaagtg catagcttgg
    88141 cgtttaaaga atgcttgtcg catagcgtcc atttcaaaaa taccagcgtg gaaaaacatt
    88201 cccgtagtgc ttttagaaac tgcctcgatt ttatgactgt cattcaattc aggaagttca
    88261 atccaaagta aacggtgtaa attttctttg atgaattttg tctgatttgc caataatgaa
    88321 agtctactaa gcccattttt ttcgccaatt tctcgcattt ctgcgctaat tctgtctata
    88381 tgtctagtta aattctcgta tgttgtttct gtcatgtttt tcacctttgt ttctatgttg
    88441 tgtaattgcc ctaagggctt tttaatgcct tttactatac tggatatcct cacactctcc
    88501 tcgaccaaaa tttgagtgtg gggattttga atggttgttt cttatacagt ttttcttgcc
    88561 tacagcctca cgctctctgg gtccaatctt tgagcgtggg gcttttttga gttgtttctt
    88621 ataacgctaa tcctcacgct cagagtcgcc aaattgaaag cgtgagaaag taccagttta
    88681 aagagttggc gctctccgta tggtcaaatt gccctaaata tgctataatc taggtataaa
    88741 tctttactaa aacctctttg ataatagctt gcctgctttg ttaaattcgt tttagtgtta
    88801 gtgtgaaagg ctctgctgat tggtctcggt aagccttttt tgttgctctc acgcgcttct
    88861 ttggcgtgtt tttttatttc tgaatgccat agctttgatt tcctgataac tcatattcaa
    88921 gccaatcatg gctattacca tatcctcaaa tgcctgatat tgctccagct cgtcactggt
    88981 caagctatca ataccgttat agcccccacg ttcttccctt aactgcttag cgttcatgtc
    89041 agttactgct tttagcagca ggttgttcat gcagtgtttt tctttttggc ttttctagcg
    89101 ccctctgcat acgaaactta gaaagttcct cacgcatttc aaagaaagct ttgaccaggt
    89161 tggttttgaa gttggccact tgctcggtgt tctttaagaa tgtaactaac aaggtcgctt
    89221 gttgttcgtt caaaatatag tccttggtat tctggccact ttccatagct tggattttaa
    89281 attcaacctt tccgaactgt tcaaacctta cttgatgttt gcggatcgtc ttggttattg
    89341 tgtgatgttg caatcccgtg cattctgcca caatactgct cagcgtataa ggctcttttt
    89401 taccgtccat atagactagt tccatcggtt tgctcctttc tagctataaa atagttcatc
    89461 tatggttata tctgatttga tttctgcaac cattgactta atcgctaggc gttctttgtc
    89521 attgaatggc gttttaccta attctttgtt gttgtatgac tgcaaagaaa tttttagctt
    89581 gtccgccatt tgttgctgag ttagtcctaa cataactcga tagcctcgta gtttactcat
    89641 agctttcccc ctttctaaaa aatccccctc catgaataga ttgaaagcgt gaaaggtcgg
    89701 aggagtttgc acattttttc tgtgcttgaa ttgtatgata cacaatattt tttctattgt
    89761 caactatttt tttaattttt gcacaaaaaa aatgtacttt ttctaagata tagtatataa
    89821 tcatctgtga aaggtgtgat aaaacatgaa tagattgaaa gaattaagac aagaaaaaaa
    89881 gctatctcaa aaagagttag ctgaaaatat tggggttcat tatcgtactc ttcaaaattg
    89941 ggaaaacgga gaaagccaaa tcaaaccaga aaaagcccaa caactagctg actacttcgg
    90001 agtaagcgtt ggatatctgt tggggtatag tgagtataga gaattagaaa aagcattgga
    90061 taaaacaatt ttttcaaact atcctgatgt tgaaacattc ctcactcaag agataaaaga
    90121 gctaatcgga gaaagaacaa aagattttta tgagtatatt gataaacaat tttatgaaag
    90181 ctataaaaat actaccgtac ctcccgaaat agttgtaaag caccgtgaag acttttatag
    90241 ctcgtttcta tttctccctg ctagattaca aaaatttata gctttatgga gcatactaac
    90301 agaaactgaa caagaaaata taggtaaaac tattgaatta ttagctatga gagggagata
    90361 aaaatccccc catattcgcc aatagcaaac cttagcacta atatttttct tttagggtag
    90421 ccgaaagtgc cgaaaatgcg acctatagca taccacgcgc cacaacgttc aacaatcatg
    90481 aagcgcgtgt tttctcaggg ttcactcttg attcgttatt agattaaata tgtaagcatt
    90541 agttagccct tatccaataa aaaccaacat ttaataaaaa gatataactc attaactttt
    90601 ttaattttta tctttcaaac aaaac
//
LOCUS       DAVEHY010000003        90316 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVEHY010000003 DAVEHY010000000
VERSION     DAVEHY010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 90316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.003"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(19..954)
                     /locus_tag="VUZ44_000241"
     CDS             complement(19..954)
                     /locus_tag="VUZ44_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU0319220.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(951..1811)
                     /locus_tag="VUZ44_000242"
     CDS             complement(951..1811)
                     /locus_tag="VUZ44_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU0319221.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKDKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1919..4081
                     /locus_tag="VUZ44_000243"
     CDS             1919..4081
                     /locus_tag="VUZ44_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU0319222.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4173..5432
                     /locus_tag="VUZ44_000244"
     CDS             4173..5432
                     /locus_tag="VUZ44_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU0319223.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTSFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5446..6312
                     /locus_tag="VUZ44_000245"
     CDS             5446..6312
                     /locus_tag="VUZ44_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU0319224.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6326..7159
                     /locus_tag="VUZ44_000246"
     CDS             6326..7159
                     /locus_tag="VUZ44_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU0319225.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7160..7240
                     /locus_tag="VUZ44_000247"
                     /pseudo
     CDS             7160..7240
                     /locus_tag="VUZ44_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7517..8959
                     /gene="gtfA"
                     /locus_tag="VUZ44_000248"
     CDS             7517..8959
                     /gene="gtfA"
                     /locus_tag="VUZ44_000248"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU0319226.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVTF"
     gene            9097..10290
                     /locus_tag="VUZ44_000249"
     CDS             9097..10290
                     /locus_tag="VUZ44_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU0319227.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10977..12956
                     /locus_tag="VUZ44_000250"
     CDS             10977..12956
                     /locus_tag="VUZ44_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0319228.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13023..14519
                     /locus_tag="VUZ44_000251"
     CDS             13023..14519
                     /locus_tag="VUZ44_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0319229.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPAAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14519..15445
                     /locus_tag="VUZ44_000252"
     CDS             14519..15445
                     /locus_tag="VUZ44_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0319230.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15454..16521
                     /locus_tag="VUZ44_000253"
     CDS             15454..16521
                     /locus_tag="VUZ44_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319231.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16532..17458
                     /locus_tag="VUZ44_000254"
     CDS             16532..17458
                     /locus_tag="VUZ44_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319232.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            17949..18464
                     /locus_tag="VUZ44_000255"
     CDS             17949..18464
                     /locus_tag="VUZ44_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU0319233.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TTPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            18486..18887
                     /locus_tag="VUZ44_000256"
     CDS             18486..18887
                     /locus_tag="VUZ44_000256"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319234.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            18899..19776
                     /locus_tag="VUZ44_000257"
                     /pseudo
     CDS             18899..19776
                     /locus_tag="VUZ44_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            19789..20592
                     /locus_tag="VUZ44_000258"
     CDS             19789..20592
                     /locus_tag="VUZ44_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU0319235.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMTIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20625..21335)
                     /gene="treR"
                     /locus_tag="VUZ44_000259"
     CDS             complement(20625..21335)
                     /gene="treR"
                     /locus_tag="VUZ44_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU0319236.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21520..23487
                     /gene="treP"
                     /locus_tag="VUZ44_000260"
     CDS             21520..23487
                     /gene="treP"
                     /locus_tag="VUZ44_000260"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU0319237.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            23665..25290
                     /gene="treC"
                     /locus_tag="VUZ44_000261"
     CDS             23665..25290
                     /gene="treC"
                     /locus_tag="VUZ44_000261"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU0319238.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25546..25794
                     /locus_tag="VUZ44_000262"
     CDS             25546..25794
                     /locus_tag="VUZ44_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU0319239.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26001..26795
                     /gene="racE"
                     /locus_tag="VUZ44_000263"
     CDS             26001..26795
                     /gene="racE"
                     /locus_tag="VUZ44_000263"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU0319240.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEKIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26792..27763
                     /locus_tag="VUZ44_000264"
     CDS             26792..27763
                     /locus_tag="VUZ44_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU0319241.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27739..28260
                     /locus_tag="VUZ44_000265"
     CDS             27739..28260
                     /locus_tag="VUZ44_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU0319242.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28257..28718
                     /locus_tag="VUZ44_000266"
     CDS             28257..28718
                     /locus_tag="VUZ44_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU0319243.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28709..29449
                     /gene="xerD"
                     /locus_tag="VUZ44_000267"
     CDS             28709..29449
                     /gene="xerD"
                     /locus_tag="VUZ44_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU0319244.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29449..30177
                     /locus_tag="VUZ44_000268"
     CDS             29449..30177
                     /locus_tag="VUZ44_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU0319245.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30196..30765
                     /locus_tag="VUZ44_000269"
     CDS             30196..30765
                     /locus_tag="VUZ44_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU0319246.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30752..31474
                     /locus_tag="VUZ44_000270"
     CDS             30752..31474
                     /locus_tag="VUZ44_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU0319247.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31474..31716
                     /gene="yidD"
                     /locus_tag="VUZ44_000271"
     CDS             31474..31716
                     /gene="yidD"
                     /locus_tag="VUZ44_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU0319248.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(31941..32906)
                     /locus_tag="VUZ44_000272"
     CDS             complement(31941..32906)
                     /locus_tag="VUZ44_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0319249.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEIATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33002..33754)
                     /locus_tag="VUZ44_000273"
     CDS             complement(33002..33754)
                     /locus_tag="VUZ44_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU0319250.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33751..34707)
                     /locus_tag="VUZ44_000274"
     CDS             complement(33751..34707)
                     /locus_tag="VUZ44_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU0319251.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(34697..35656)
                     /locus_tag="VUZ44_000275"
     CDS             complement(34697..35656)
                     /locus_tag="VUZ44_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0319252.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36079..36780)
                     /gene="galE"
                     /locus_tag="VUZ44_000276"
     CDS             complement(36079..36780)
                     /gene="galE"
                     /locus_tag="VUZ44_000276"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU0319253.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHYAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPATEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37181..38245
                     /gene="pepA"
                     /locus_tag="VUZ44_000277"
     CDS             37181..38245
                     /gene="pepA"
                     /locus_tag="VUZ44_000277"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU0319254.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38267..38563
                     /locus_tag="VUZ44_000278"
     CDS             38267..38563
                     /locus_tag="VUZ44_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU0319255.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39245..39688
                     /locus_tag="VUZ44_000279"
     CDS             39245..39688
                     /locus_tag="VUZ44_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU0319256.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            39692..40456
                     /locus_tag="VUZ44_000280"
     CDS             39692..40456
                     /locus_tag="VUZ44_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU0319257.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40471..41199
                     /locus_tag="VUZ44_000281"
     CDS             40471..41199
                     /locus_tag="VUZ44_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319258.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            41192..42712
                     /locus_tag="VUZ44_000282"
     CDS             41192..42712
                     /locus_tag="VUZ44_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU0319259.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKYPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43056..43862
                     /locus_tag="VUZ44_000283"
     CDS             43056..43862
                     /locus_tag="VUZ44_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU0319260.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44028..44564)
                     /locus_tag="VUZ44_000284"
     CDS             complement(44028..44564)
                     /locus_tag="VUZ44_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU0319261.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHIASLLFS
                     KNDYFLRQLQRELEHHVYPMLAADLKQTHPSLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            44697..45587
                     /locus_tag="VUZ44_000285"
     CDS             44697..45587
                     /locus_tag="VUZ44_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU0319262.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     VSLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            45831..46184
                     /locus_tag="VUZ44_000286"
     CDS             45831..46184
                     /locus_tag="VUZ44_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU0319263.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSACVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46185..47222
                     /locus_tag="VUZ44_000287"
     CDS             46185..47222
                     /locus_tag="VUZ44_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU0319264.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(47268..48275)
                     /gene="galR"
                     /locus_tag="VUZ44_000288"
     CDS             complement(47268..48275)
                     /gene="galR"
                     /locus_tag="VUZ44_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU0319265.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTIAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48440..49618
                     /locus_tag="VUZ44_000289"
     CDS             48440..49618
                     /locus_tag="VUZ44_000289"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU0319266.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGSGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49637..51118
                     /locus_tag="VUZ44_000290"
     CDS             49637..51118
                     /locus_tag="VUZ44_000290"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU0319267.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFAHVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            51188..51592
                     /locus_tag="VUZ44_000291"
     CDS             51188..51592
                     /locus_tag="VUZ44_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU0319268.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTFQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            51749..52603
                     /locus_tag="VUZ44_000292"
     CDS             51749..52603
                     /locus_tag="VUZ44_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEU0319269.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            52629..53399
                     /locus_tag="VUZ44_000293"
     CDS             52629..53399
                     /locus_tag="VUZ44_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU0319270.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            53386..54252
                     /locus_tag="VUZ44_000294"
     CDS             53386..54252
                     /locus_tag="VUZ44_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEU0319271.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(54339..55601)
                     /locus_tag="VUZ44_000295"
     CDS             complement(54339..55601)
                     /locus_tag="VUZ44_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU0319272.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(55601..56182)
                     /locus_tag="VUZ44_000296"
     CDS             complement(55601..56182)
                     /locus_tag="VUZ44_000296"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU0319273.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(56582..56677)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(57060..57299)
                     /locus_tag="VUZ44_000297"
     CDS             complement(57060..57299)
                     /locus_tag="VUZ44_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU0319274.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(57299..57442)
                     /locus_tag="VUZ44_000298"
     CDS             complement(57299..57442)
                     /locus_tag="VUZ44_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU0319275.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(57454..58281)
                     /gene="xth"
                     /locus_tag="VUZ44_000299"
     CDS             complement(57454..58281)
                     /gene="xth"
                     /locus_tag="VUZ44_000299"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU0319276.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTITFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            58415..58870
                     /locus_tag="VUZ44_000300"
                     /pseudo
     CDS             58415..58870
                     /locus_tag="VUZ44_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            59023..59319
                     /locus_tag="VUZ44_000301"
     CDS             59023..59319
                     /locus_tag="VUZ44_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU0319277.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            59525..61270
                     /locus_tag="VUZ44_000302"
     CDS             59525..61270
                     /locus_tag="VUZ44_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319278.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQTAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFAPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            61260..63011
                     /locus_tag="VUZ44_000303"
     CDS             61260..63011
                     /locus_tag="VUZ44_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319279.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEDLLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            63184..63876
                     /locus_tag="VUZ44_000304"
     CDS             63184..63876
                     /locus_tag="VUZ44_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU0319280.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            63919..65145
                     /locus_tag="VUZ44_000305"
     CDS             63919..65145
                     /locus_tag="VUZ44_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU0319281.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            66308..68419
                     /gene="pfbA"
                     /locus_tag="VUZ44_000306"
     CDS             66308..68419
                     /gene="pfbA"
                     /locus_tag="VUZ44_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU0319282.1"
                     /translation="MKYFVPNEVFSIRKLKVGTCSVLLAISILGSQGILSDEVVTSSS
                     PMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNSISSNGTIRSNS
                     QLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAI
                     QDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIV
                     FMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNS
                     NNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEP
                     LTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKIL
                     NNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLL
                     DLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNI
                     ELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKE
                     PVIRDSDGNFNIVTENGLYKIVTNNLSDKNKEEKQSNSNNVIDSNQKNGEFNSSKDNR
                     QMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKIMELFL
                     TVTGIGLLLTLKGLKYYGKDK"
     gene            68403..68699
                     /locus_tag="VUZ44_000307"
     CDS             68403..68699
                     /locus_tag="VUZ44_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319283.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            69042..69254
                     /locus_tag="VUZ44_000308"
     CDS             69042..69254
                     /locus_tag="VUZ44_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319284.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            69312..69953
                     /locus_tag="VUZ44_000309"
     CDS             69312..69953
                     /locus_tag="VUZ44_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU0319285.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNIDKKGYELICLQYPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSI
                     NMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            69966..71441
                     /gene="galT"
                     /locus_tag="VUZ44_000310"
     CDS             69966..71441
                     /gene="galT"
                     /locus_tag="VUZ44_000310"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU0319286.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEENAIADYHLEWADQLKEKYPRINKEEVN
                     NVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            71454..72464
                     /gene="galE"
                     /locus_tag="VUZ44_000311"
     CDS             71454..72464
                     /gene="galE"
                     /locus_tag="VUZ44_000311"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU0319287.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            72644..73303
                     /locus_tag="VUZ44_000312"
     CDS             72644..73303
                     /locus_tag="VUZ44_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU0319288.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            73328..74395
                     /locus_tag="VUZ44_000313"
     CDS             73328..74395
                     /locus_tag="VUZ44_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU0319289.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            74499..75509
                     /locus_tag="VUZ44_000314"
     CDS             74499..75509
                     /locus_tag="VUZ44_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319290.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            75521..77212
                     /locus_tag="VUZ44_000315"
     CDS             75521..77212
                     /locus_tag="VUZ44_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU0319291.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            77215..77925
                     /locus_tag="VUZ44_000316"
     CDS             77215..77925
                     /locus_tag="VUZ44_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU0319292.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            78021..78389
                     /locus_tag="VUZ44_000317"
     CDS             78021..78389
                     /locus_tag="VUZ44_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319293.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            78497..79498
                     /locus_tag="VUZ44_000318"
     CDS             78497..79498
                     /locus_tag="VUZ44_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU0319294.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            80106..80183
                     /locus_tag="VUZ44_000319"
                     /pseudo
     CDS             80106..80183
                     /locus_tag="VUZ44_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            80639..82000
                     /gene="trpE"
                     /locus_tag="VUZ44_000320"
     CDS             80639..82000
                     /gene="trpE"
                     /locus_tag="VUZ44_000320"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU0319295.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            81997..82563
                     /locus_tag="VUZ44_000321"
     CDS             81997..82563
                     /locus_tag="VUZ44_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU0319296.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            82574..83578
                     /gene="trpD"
                     /locus_tag="VUZ44_000322"
     CDS             82574..83578
                     /gene="trpD"
                     /locus_tag="VUZ44_000322"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU0319297.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            83575..84342
                     /gene="trpC"
                     /locus_tag="VUZ44_000323"
     CDS             83575..84342
                     /gene="trpC"
                     /locus_tag="VUZ44_000323"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU0319298.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            84329..84928
                     /locus_tag="VUZ44_000324"
     CDS             84329..84928
                     /locus_tag="VUZ44_000324"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU0319299.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            84906..86129
                     /gene="trpB"
                     /locus_tag="VUZ44_000325"
     CDS             84906..86129
                     /gene="trpB"
                     /locus_tag="VUZ44_000325"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU0319300.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            86122..86898
                     /locus_tag="VUZ44_000326"
     CDS             86122..86898
                     /locus_tag="VUZ44_000326"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU0319301.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(86870..86971)
                     /locus_tag="VUZ44_000327"
                     /pseudo
     CDS             complement(86870..86971)
                     /locus_tag="VUZ44_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            87200..87340
                     /locus_tag="VUZ44_000328"
     CDS             87200..87340
                     /locus_tag="VUZ44_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319302.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            87377..87931
                     /locus_tag="VUZ44_000329"
     CDS             87377..87931
                     /locus_tag="VUZ44_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319303.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            87946..89097
                     /locus_tag="VUZ44_000330"
     CDS             87946..89097
                     /locus_tag="VUZ44_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU0319304.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(89149..89808)
                     /locus_tag="VUZ44_000331"
     CDS             complement(89149..89808)
                     /locus_tag="VUZ44_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU0319305.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLSQVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            89878..90276
                     /locus_tag="VUZ44_000332"
     CDS             89878..90276
                     /locus_tag="VUZ44_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0319306.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVALIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NRDIDSISLNVFEANQRAQNLYQKEGFEIV"
BASE COUNT        27331 a        15906 c        19932 g        27147 t
ORIGIN      
        1 tattataatt gtgttatttt acttccaact attgagagaa atttcgccac tatttagcca
       61 gatttctttt ccgttatcac attgaactaa aagttttcca ttttctgaga tgtctttagc
      121 aagtcccttg tagtcttttt gctgtagtgt gaaagtgact tcttttccta gaatgaatga
      181 ctgttttttg tataggtata atagctcttc tgctggtgtt tcgaagaaag cacgccagat
      241 ttctatgatc aattcattcc ttgttatagg agctgtagct ttaaataagc tggcagcttt
      301 ttcttttaat tcctgaggga agtctttaat agtgaaattg atacctactc caataatgat
      361 atctgtgact aagccagttt ctacagaggt cattgcttca gtaaggattc ctccaatttt
      421 atgattgttt agatagatat cattgaccca ttttatgtcg acatctatta aagttaggtt
      481 cttaatagct ttgtagacag ctccagctac aagtagtgtg taggatggta atttgtcata
      541 ggggagattt ggtttaagat ggagtgtcat ataaatacca ccttgtggtg agtagaagga
      601 acgttgaaaa cgtcctcggc ctgctgtttg ataggaagct agatagaggg tatttgcttc
      661 atggcctaaa tcaattgctt cttttgcatc tagttgtgtt gattttgttt cgggtttaaa
      721 gctgacttta attggaagat tttcttctag aatctctgga agaataaggt caccattcat
      781 tagtttatat cctctatttt tgatactatc aatttcaatg ccttcttgtt ctagtcgctt
      841 gatagctttc caaattgatg ttcggcttag ggatagtttt tctgcgattt tttctccgct
      901 gatatagtcg gtttctttag ataggatttg gtagacagct tggtaggatt tcataatgtt
      961 gcctttctca ctagttggta ttgagagtat tcttttcttg tatgacttgg agtctgatta
     1021 aagtattgtt tataagcttt cgaaaaatgg agtggatctg aaaaacctac cgagtatgca
     1081 attaccttga tggactcttg ggtattttcg agaagttgtc tagctcggtg cattcgaacg
     1141 tagagtaggt attctttggg tgataaggta ttaaattctt tgaatacgct tgataagtag
     1201 cttctgtgaa cggatagttc ttttgctaaa tcttgaattg taagtgattg aggatagtgg
     1261 ctatcaatta atcgtttgca ttcaagatag agttggtggg ttgatgaaat attctttttt
     1321 ttctgattgg gagcaatagt tcccagatga aacatcagtt catgaagttg tcccatgata
     1381 tggagttgag ctaattcact tgattttgta atctgagcga agcggacaat gtctgagatg
     1441 agttttgcag tagtctgggt atgacaagtt tcagattgga tgagatagga ttgatcagaa
     1501 atttgagaaa gagcaaaata atcaggggat ttccctccag tgattcctaa ccagtagtag
     1561 gcccaaggtt ctttactatc tgcttgataa aaggttagtt cctctggttt taatagaaag
     1621 aaatctcctt cttttaaatc aacaatttta tccttgtaat gaaattttcc ttgtccttta
     1681 gtaatgtaat gtaggacgta tgtatcacga atggctggac caaaagagta attaggtgtg
     1741 cattcctcat atccataaaa gcttagggca aggtcgattg ttccagtctg gtattctgaa
     1801 aaaactaaca tgtgctacct cctacctaac attttaccat attcttgaga catttttcta
     1861 ttttggaaag cgatttcagg tgataaaata taatcaataa agtgatgagg tgaagtaaat
     1921 gggagttagg atagagaata atctatttta tgttgagagt aaaaatctaa gtttgattat
     1981 tgaaaatcga aatggctact tacttttgaa acatttagga aagactatta agaactataa
     2041 aggttccaat agtgtttatg aacgagacca tgccttttca ggaaatccaa cggctactaa
     2101 tcgaaccttt agtttagata ctcagcgaca gatttttgga caacatggct taggagattt
     2161 taggaaacca actatacagg ttcagcatag tgtaactgaa gtaacagact ttcgatttgt
     2221 agaagcaaag attttaaaag gtcagaatgg tccacagggc ttaccttctc cacatagcat
     2281 ggacgataca gagactcttg tcttaatgtt agaagattct aaggctcaac ttagtctgac
     2341 tttgtattat actactttta ataatgatgc gactattact agctacagta aattagataa
     2401 taatagtaat caggaagttg tcatccataa agatttttct tttatggctg attttccagc
     2461 tgcagattat gaaatagcaa ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg
     2521 tcaacaggta gaacaaggaa tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc
     2581 tcaaacacca gctcttctac tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt
     2641 tgctattcaa ctaatgtata gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa
     2701 tgaagttcgg gtggctattg gcattaatcc agaaaacttt tcttggaagt tagcccctga
     2761 ggaatacttt gaaacaccgg tagctttagt gactcattca gatcagggat taactggtat
     2821 tagtcatgaa agtcagaatt ttgtactgaa gcacattatg ctaagtgaat tttctaaaaa
     2881 agaacgtcca attctaatca ataactggga agctacttac tttgactttc agagagaaaa
     2941 actgttagag ttagcagatg aagctaagaa agttggcatt gaactttttg tattagatga
     3001 tggttggttt ggcaatcgtt ttgatgataa tcgtgcttta ggtgattggg ttgttaatga
     3061 ggaaaaactg ggtggaagtc tagaaagtct gatttcagct atccatgaaa gaggtttgca
     3121 gtttggactt tggttagaac ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca
     3181 tcctgactgg gctattcagg ttcctgatta tgagcatact tattctcgga atcaattagt
     3241 acttaatctt gccaatcctc aggtagtaga atacttgaaa agtgtcttag atcaactcct
     3301 atcttatcat gagattgatt acattaaatg ggatatgaac cgcaatatca ctaagctagg
     3361 gaatggatta acttatctag agacacagat gcaatctcat cagtacatgc tggggcttta
     3421 cgaactcgtt tcttatctga cagagaagca cagccatatt ctctttgagt cctgctctgg
     3481 tggtggtgga cgaaatgatc ttggtatgat acgctatttc ccacaagtct gggctagtga
     3541 taatactgat gccattgcac gtttaccaat tcaatacggt tcatcctatc tctatccaac
     3601 catttctatg ggggctcatg tgtcagcagt accgaatcat cagatgggac gaatgacacc
     3661 attagaaaca cgtggccatg tagcaatgat gggaaatttg ggctatgagc ttgatttgac
     3721 aaatttatca gatgaagaga aagctacgat tgctaatcag gtgaacttgt ataaagaatt
     3781 acgaccagta gttcagttag gacagcagta tagactaatt aatcctgata ctgcatccaa
     3841 tgaagcagct gtacaattta attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt
     3901 atctgttgta gagaccatgg aaacaacttt aaaattaaaa gatttggatg aagagggact
     3961 atataaatta caggaaaatg gcgaagttta ctcaggtgca gaactaatgt atgcgggctt
     4021 aactgttatc ttatcccaag gagatttttt gagtagacag tatattttta gaaaactatg
     4081 atatgtactg accccaaaag ttagatttat tctgtctaac ttttggggtg cagttcaata
     4141 agggtgtata aatttataaa ggaggctttc taatggaatg gtataaaaaa atcggacttc
     4201 ttgcaactac aggtttagct ttgtttgggc tcggcgcttg ctccaactat ggtaaatctg
     4261 cggatggcac agtgaccatc gagtatttca accagaaaaa agaaatgacc aaaaccttgg
     4321 aagaaatcac tcgtgatttt gagaaggaaa accctaagat caaggtcaaa gtcgtcaatg
     4381 taccaaatgc tggtgaagta ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg
     4441 tcaatattta cccacagtcc atcgaactgc aagaatgggc aaaagcaggt gtttttgaag
     4501 atttgagcaa caaagactac ctgaaacgcg tgaaaaatgc ctacgctgaa aaatatgctg
     4561 taaacgaaaa agtttataac gttcctttta cagctaatgc ttatggaatt tactacaaca
     4621 aagataaatt cgaagaactg ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt
     4681 tagtcaaaga tatcgttgct aaaggacaaa catcatttgg aattgcaggt gcagatgctt
     4741 ggacactcaa tggttacaat caattagcct ttgcgacagc aacaggtgga ggaaaagaag
     4801 caaatcaata ccttcgttat tctcaaccaa atgccattaa attgtcggat ccgattatga
     4861 aagatgatat caaggtcatg gacatccttc gcatcaatgg ctctaagcaa aagaactggg
     4921 aaggtgctgg ctataccgat gttatcggag ccttcgcacg tggggatgtc ctcatgacac
     4981 caaatgggtc ttgggcgatc acagcgatta atgaacaaaa accgaacttt aagattggaa
     5041 ccttcatgat tccaggaaaa gaaaaaggac aaagcttaac cgttggtgcg ggagacttgg
     5101 catggtctat ctcagccacc accaaacatc caaaagaagc caatgccttt gtggaatata
     5161 tgacccgtcc agaagtcatg caaaaatact acgatgtgga cggatctcca acagcgatcg
     5221 aaggggtcaa acaagcagga gaagattcac cgcttgctgg tatgaccgaa tatgccttta
     5281 cggatcgtca cttggtctgg ttgcaacaat actggaccag tgaagcagac ttccatacct
     5341 tgaccatgaa ctatgtcttg accggtgata aacaaggcat ggtcaatgat ttgaatgcct
     5401 tctttaaccc gatgaaagcg gatgtggatt aggagtagag agactatgaa aaaagtatta
     5461 caaaaatatt gggcatgggc ttttgtggtc atccccctct tgttacaagc aattttcttc
     5521 tatgtgccga tgtttcaagg agccttttac agttttacca actggacagg attgacttac
     5581 aactacaaat ttgtcggctt aaacaacttt aagctcctct tcatggatcc aaaattcatg
     5641 aatgcgattg gctttaccgc aatcattacg attgccatgg tggttggtga gattgcactc
     5701 gggatcttca ttgcgcgtgt cttgaactct aaaatcaaag gccaaacctt cttccgtgct
     5761 tggttcttct tcccagctgt tttatctggt ttgacagtgg ctttgatctt caagcaagtc
     5821 ttcaactacg gtcttccagc gattgggaat gcccttcata ttgaatttct ccaaaccagt
     5881 cttttaggga ctaagtgggg agcaatcttt gcggctgtct ttgtccttct ttggcaaggg
     5941 gtggctatgc ccatcatcat cttcctagct ggtttgcaat ctattccaac tgagattaca
     6001 gaggcagcaa ggattgatgg tgcgactagc aagcaagttt tctggaacat tgaattgcct
     6061 tacttgctac caagtgtctc tatggtcttt atcctagccc taaaaggtgg gctgactgcc
     6121 tttgaccaag tctttgccat gaccggtggt ggtccaaaca atgccacaac ctcacttggg
     6181 ctcttggttt ataactatgc ctttaaaaac aaccaattcg gttatgccaa tgccattgcc
     6241 gtaatcttgt tcctcttaat tgtagtgatt tcgatcatcc aattgagagt atctaagaaa
     6301 tttgaaattt aagaggagaa gcatgatgaa acaagatgaa agaaaagccc tgattggcaa
     6361 atacattcta ttgattctag gatcggttct gattttagtg ccgctccttg ctaccctctt
     6421 tagttccttc aaacccacta aggatattgt agataatttc tttggctttc caaccaactt
     6481 cacatgggac aactttagcc gtctcttagc tgatgggatt ggaggctatt attggaactc
     6541 tgtcgtcatc actgtcttgt ctttacttgc agtaatgatc tttatcccta tggcagccta
     6601 ctccatcgct cgcaatatga gtaaaagaaa agtctttacc atcatgtata ccctcttaat
     6661 cctcggaatc ttcgtacctt tccaagtcat catgattccg attacggtta tgatgagtaa
     6721 actcggtttg gctaatacct ttggtttgat cttgctctac ttgacctatg cgattccaca
     6781 gaccctcttt ctctatgttg gctatatcaa aatctcgatt ccagaaagtc tggatgaagc
     6841 agcagagatc gatggggcta atcaatttac aacctatttc cgcatcatct tcccaatgat
     6901 gaaaccgatg catgcgacaa ccatgatcat caatgccctt tggttctgga atgacttcat
     6961 gttgccactc cttgtcttga accgggattc caaaatgtgg actctgcctt tgttccaata
     7021 caactacgca ggccaatatt tcaacgacta cggaccaagc tttgcctctt acgtggtcgg
     7081 cattatcagt atcaccattg tctatctctt cttccaacgc catatcattt caggaatgag
     7141 caacggggca gtgaagtaat actcaatgaa aatcaaagag caaactagga agctagccgc
     7201 aggttgctca aaacactgtt ttgaggttgt ggatgaaact gacgaagtca gtaaccatac
     7261 ctacggtaag gtgaagctga cgtggtttga agagattttc gaagagtata agaagagctc
     7321 atggaatcta tagtctttga cacagaggaa gagttcagct tgttgataat tctatgtaga
     7381 aaacaagaaa gtagtacttt gtttatcaca gtctatatta gtacgagttt gatgataaat
     7441 agagatttaa aatgaatttg atttacgaag ccagatcata tgagacttgg cttcaattag
     7501 aaaaaggaga gtaatgatgc cgattcaaaa taaaaccatg ttgattacct attctgatag
     7561 ccttggaaat aatcttaaag acttatatga taatttggaa gagcattttg gagatgctat
     7621 tggaggagtt caccttttac catttttccc atcaacaggt gatcgtggat ttgcgccagt
     7681 tgactacgac gaagtggact cagcttttgg tgattgggag gatgttaagc gtttaggtga
     7741 gagatattat cttatgtttg attttatgat taatcatatt tctcgtcaat ccaagtatta
     7801 taaggactat caagaaaaac atgaagccag tgaatttaaa gctctctttt taaactggga
     7861 taagttttgg ccagaaaacc gtccgacaca gtctgatgta gatttaattt acaagcgtaa
     7921 ggatcgtgca ccaaagcaag agattgtgtt tgaagatggt tcagtggaac atttgtggaa
     7981 tacctttggt gaggagcaga ttgatcttga tgtgaccaaa gaagtaacta tggaatttat
     8041 ccgtaagacc attcagcact tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt
     8101 tgcttatgca gtgaagaaat tggatactaa tgatttcttt gtggaaccag atatttggga
     8161 tttattggac aaagttcgag atatcgctgc tgagtatggg acagagcttt tacctgagat
     8221 tcatgaacac tattcgattc agtttaaaat agcagaccat gattactatg tttatgattt
     8281 tgctcttcca atggtgacac tttatactct ttacagttcc agaacagagc gtttggctaa
     8341 gtggttaaag atgagcccga tgaagcaatt tacgacgcta gatacccatg atgggattgg
     8401 agtagtagat gtcaaggata tcctgaccga tgaggagatt gactatgctt caaatgaact
     8461 ctataaggtt ggagccaatg tcaaacgtaa gtactctagt gccgagtata acaacttaga
     8521 tatctaccaa atcaattcaa cctactattc agcgcttgga gatgatgatg tcaagtattt
     8581 tctcgctcgt ctaattcaag cttttgcccc aggtattcct caggtttact atgtgggtct
     8641 attagcaggc aagaatgact tgaaattatt agaagaaact aaagaaggtc gaaatattaa
     8701 tcgtcattac tatagcaacg aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc
     8761 ccttctcaat ctattttctt tccgtaaccg ttcagaagcc tttgatctag aggggactac
     8821 tgagatagag acaccaacag ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc
     8881 cgtaacagca gtagtagaaa ttgatttgca aaatcagact tatcgggtaa ttgagaatgg
     8941 agttgaagta acattttgaa gccttgatat ggtggataaa atagggtttt tattttggaa
     9001 aacgtttcct ttgttttcaa attgctaaaa aagtggtaca atataggata gcttactatt
     9061 atctgaatca gcagatttgg agagaaagga ttcattttga aatcaatagg ctttattgaa
     9121 aagctgaagg ggttgtctag taaagagctg attttattgg gaattatcct aagtatcttt
     9181 ttaccctttt atctttttgt agttgtactc tgtttatata ttatcagttt gatttttaca
     9241 ggagacatga aaagtattct tcagaaaatg ggggagcatc cgatgctgct tctttttctt
     9301 agctatagta ctgttatatc cattcttgca caaaattgga tgggtcttgt ggcttcagta
     9361 ggaatgtttc tatttactat tttctttttg cactatcagt cgattttatc ccataaattc
     9421 tttcgattga ttttgcagtt cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt
     9481 ttagaacatt tccaaattgt gaagaaattt aactatgctt ttctttcacc caatatgcag
     9541 gtgtggcatc agaaccgggc agaagtgacc ttctttaatc ctaattatta tggaattatt
     9601 tgttgtttct gtattatgat tgctttctat ctgtttacaa cgaccaagtt gaattggttg
     9661 aaagtattct gtgtgattgc aggctttgtt aatctctttg gtttgaactt tactcaaaat
     9721 cgaactgcct ttcctgctat tatcgctgga gcaattatct atctctttac gactattaaa
     9781 aactggaagg ctttttggct tagtattggg gtcttcgcga ttggtttgag tttcctcttt
     9841 tctagtgatt tgggagttcg aatgggtact ttagactctt ctatggaaga acgcatttct
     9901 atctgggatg ctgggatggc cttgtttaag caaaatcctt tttggggtga agggccattg
     9961 acctatatgc actcttatcc tcggatacat gctccttatc atgaacatgc ccacagtctt
    10021 tatattgata cgattctgag ttacggaatt gtgggtacca ttttattagt tctgtcttct
    10081 gttgctcctg ttcgtttgat gatggatatg agtcaggagt cggggaaacg tccgattatc
    10141 ggcctttatc tatctttcct tacagtggtt gctgtgcacg gaatttttga cttggctctc
    10201 ttctggattc agtcaggctt tattttcttg ctagttatgt gcagtattcc attggagcat
    10261 cgaatgttgg tatcggacat gacggattaa gttttataag tttgaaatct tctaccttgg
    10321 gtaggagatt tttttatacg atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg
    10381 gatccactac cggtgaatac aatagcgctc cccaagcctg actatcgtga ggtagcggat
    10441 taaaatggtc tggggataga tcgttttaag tctgacgcag gaaataagaa ttgtcagaga
    10501 aagcaatagt gaaatcgtag gctatgaata gaaacgtgat agcgaggagc atatagtgga
    10561 caaggtagcg agaaatttta aagtataaaa gatagtctta atctatatgt gtaaatcacg
    10621 aaagtaattg aattcggaat aaggttggtg tgaaaagaca tagtaaactg aatcttgaat
    10681 actagaatga tacttctaca atattgttat aatttaattt gaattccaaa atcacattgt
    10741 tccgtccgta tttcatttta ctgtatgtct tcctaagctc caaaatttct gtgtcaaatt
    10801 tcctattttc actgtagtct ttgacacttc gaacgacaat ttgaatcata tattcaaaaa
    10861 aaaatgaaaa atttgtgcca acaagcctaa atattctgaa aatttgtttg atttttaatg
    10921 gataatgtga tataatggtt gtcaatctat aattcacata aacagaggag tagaaaatga
    10981 aaaaaaatcg tgtatttgct acagcaggtc ttgttttatt agcagcaggt gtacttgcag
    11041 catgcagttc ttcaaaatca tctgattcat cagcccctaa agcttatggc tatgtttata
    11101 cagcagaccc agaaaccttg gactacctga tttcaagtaa aaatagtaca acagtagtga
    11161 cttcaaatgg gattgatggt ttattcacta acgataatta cggtaatctt gctcctgcag
    11221 ttgcagagga ttgggaagtc tctaaggatg gtttgaccta cacttataag attcgtaaag
    11281 gggttaaatg gtttacctct gatggagaag aatatgcaga ggtgacggct aaagatttcg
    11341 tgaacggttt aaaacacgca gcagataaaa aatcagaagc tatgtattta gctgaaaatt
    11401 cggttaaagg cttggcagat tatctatcag gaacttcaac agatttttca acagttggtg
    11461 tcaaggcggt tgatgattat acgttacaat acactttgaa ccagcctgaa ccgttctgga
    11521 actctaagtt gacctattct attttctggc ctctgaatga agaattcgaa acatcaaaag
    11581 gaagcgattt tgctaaacca acagatccga catccttgct ttataatggt ccattcttgt
    11641 tgaaagggtt gactgcaaaa tcttctgtag agtttgtaaa aaatgagcaa tattgggata
    11701 aagaaaatgt ccacctagat actatcaatc tagcttacta tgatggatca gatcaggagt
    11761 cgctagagcg taacttcact agtggagctt atagttatgc ccgtctttac cctaccagct
    11821 ccaactattc taaggttgca gaagaataca aggacaatat ctattacaca caatcaggct
    11881 ctgggattgc tggtctgggt gtgaatattg atcgccaaag ttacaactat acttctaaaa
    11941 ctacagattc agagaaagta gctactaaga aggcattgct taacaaagat ttccgtcaag
    12001 ccttgaattt tgctcttgat cgctcagctt actcagctca aatcaatggt aaagatggag
    12061 cagctttagc agttcgtaat ttatttgtaa aaccagactt tgtttcagct ggtgagaaga
    12121 cctttggtga tttagtcgct gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga
    12181 atttagctga tgggcaggat ggtttattca atgctgacaa ggccaaggca gagtttgcga
    12241 aagctaagaa agctttagaa gcagacggcg ttcagtttcc tattcatctg gacgttccag
    12301 tagaccaagc atcaaaaaac tacatatctc gtattcagtc ctttaaacaa tctgtagaaa
    12361 cagttcttgg tgttgaaaat gtcgttgttg atattcaaca aatgacaagt gatgaattcc
    12421 ttaatattac ttactatgct gccaatgctt catctgagga ttgggatgta tcaggaggag
    12481 tttcatgggg gccagactat caagacccat ctacttacct ggatatttta aaaacaacta
    12541 gcagtgaaac tacaaaaaca tatttaggat ttgataatcc aaatagccct tcagtagttc
    12601 aagttggttt gaaagaatac gataaattag ttgatgaagc tgccaaagag acaagcgact
    12661 tgaatgtccg ttatgaaaaa tatgcagcgg ctcaagcatg gttgacagat agttcactct
    12721 ttattcctgc tatggcttct tctggtgcag caccagtgct ttcacgaatt gttccattta
    12781 ctggagcttc tgcgcaaaca ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat
    12841 tacaagataa agcggtgact aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag
    12901 aaaaagctga atcaaatgag aaagctcaaa aagaattggc aagtcatgtg aagtaaataa
    12961 tttctaatag aactttctct ccatgaggag aaggttcttt tgggattttt aaaggaaata
    13021 atatgaaaaa atatattttt atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa
    13081 cgactttgac ctacacgatt atctatacct tggttcctcg aaaattgatt ttcaagcagg
    13141 atcctaacta taataaaatt gcgacaacgg ctgataaacg tgataactat gaaaatactg
    13201 tgtttgagcg tatgggctac attgagtatt acgatactaa agagttgcaa gaaaaggcaa
    13261 gtagcatgga ttcttctgta acagtagaag caaatgcgac caataaagct atttatgaaa
    13321 agtacatcaa tcaattaggt catggttgga ctttgggaga atttactgaa agtggtcaat
    13381 tctatgctac tcgtgaaatt ccaatttttg aacgtgtttt tcacttctat gctaacttga
    13441 ttgacattga ccatacaaat aaaatccaag accctgaaaa tccagacttg aaacgctacc
    13501 ttcgttttga aaatgatcca gctatcggat ggtcattggt cggttcagga actaaacata
    13561 aatatctctt gtactttaac agtcagttcc catttgttca tcaaaacttt gtgaacttga
    13621 atttaggtga ctcttaccca acctatgcta atacaccagt tcttcaggtt attactcaag
    13681 gtcaaggaca aaccaaaact gcccaagttc agttcccaac aggtaagaaa acgtcttctg
    13741 taaatattta ctcaagaacc tacaagtcac ctagtcaggc tgactctcgt gaagtagcta
    13801 gctatgggaa agatgatcct tatacagcga ctgaaagtaa ttaccaatat ccatctatga
    13861 ttgtcagctc tgctattact ggtttgattg gtttggttct tgcctatgct cttgccgtgc
    13921 cacttggttc agccatggct cgtttcaaga acacttggat tgatagcctc tcaacagggg
    13981 ctttgacctt cttgcttgct cttccaacga ttgccttggt ttacatcgtt cgattgattg
    14041 gatcatctat tgcccttcca gattcattcc ctatcttggg agctggagat tggcgttctt
    14101 acgttttacc agcagtcatc cttggtttgt tgggtgctcc tggtacagcc atttggattc
    14161 gtcgttacat gattgacttg caatctcaag actttgttcg tttcgctcgt gcaaaaggtt
    14221 tgtctgaaaa agaaatttca aacaaacaca tctttaaaaa tgccatggtt ccgctggttt
    14281 caggaattcc tgctgccatt attggggtta tcggtggtgc aacccttact gaaacagtct
    14341 tcgccttccc aggtatgggt aaaatgttga ttgactctgt aaaagcatct aataactcta
    14401 tggtcgttgg tcttgtcttc atctttacat gtatttctat cttctcacgt cttttgggag
    14461 atatttggat gactattatt gacccacgta ttaaattgac tgagaaagga ggcaaataat
    14521 gtctacaatc gataaagaaa aatttcagtt tgtaaaacgt gacgattttg cctctgaaac
    14581 tattgatgcg ccagcatatt cttactggaa atcagtgttt aaacaattta tgaagaaaaa
    14641 atcaactgta gtcatgttgg gaatcttggt agccatcatt ttgataagtt tcatctaccc
    14701 aatgttttct aagtttgatt tcaatgatgt cagcaaggta aacgacttta gtgttcgtta
    14761 tatcaagcca aatgcggagc attggttcgg tactgacagt aacggtaaat cgctctttga
    14821 cggtgtctgg ttcggagctc gtaactccat cctcatttct gtgattgcga cagtgattaa
    14881 cttggttatc ggtgtttttg tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt
    14941 catgatggaa gtttacaacg tcatctcaaa catcccacct cttttgattg ttattgtctt
    15001 gacttactca atcggagctg gattctggaa tctgattttt gccatgagcg taacaacatg
    15061 gattggtatt gccttcatga tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa
    15121 cttggcgtca cgtactttgg gaacaccaac cttgaagatt gttgccaaaa atatcatgcc
    15181 tcaattggta tctgttattg tgacaaccat gactcaaatg cttccaagct ttatctcata
    15241 cgaagccttc ttgtctttct tcggtcttgg attaccgatt acagtgccaa gtttgggtcg
    15301 tttgatttcg gattattcac aaaacgtaac aaccaatgct tacttgttct ggattccatt
    15361 gacaaccctt gtcttggtat ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc
    15421 tagtgatcca cgtacacata gataggagta gaaatgacaa aagaaaaaaa tgtaattttg
    15481 actgctcgcg atattgtcgt ggaatttgac gttcgtgaca aagtattgac agccattcgc
    15541 ggcgtttccc ttgaactagt cgaaggagaa gtattagcct tggtaggtga gtcaggatca
    15601 ggtaaatctg ttttgacaaa gaccttcaca ggtatgctcg aagaaaatgg tcgtattgcc
    15661 caaggtagta ttgactaccg tggtcaggac ttgacagctt tatcttctca caaggattgg
    15721 gaacaaattc gtggtgctaa gattgcgact atcttccagg acccaatgac tagtttggac
    15781 cccattaaaa caattggtag tcagattaca gaagttattg taaaacacca aggaaaaaca
    15841 gctaaagaag cgaaagaatt ggccattgac tacatgaata aggttggcat tccagacgca
    15901 gatagacgtt ttaatgaata cccattccaa tattctggag gaatgcgtca acgtatcgtt
    15961 attgcgattg cccttgcctg ccgacctgat gtcttgatct gtgatgagcc aacaactgcc
    16021 ttggatgtaa ctattcaagc tcagattatt gatttgctaa aatctttaca aaacgagtat
    16081 catttcacaa caatctttat tacccacgac cttggtgtgg tggcaagtat tgcggataag
    16141 gtagcggtta tgtatgcagg agaaatcgtt gagtatggaa cggttgagga agtcttctat
    16201 gaccctcgcc atccatatac atggagtctc ttgtctagct tgcctcagct tgctgatgat
    16261 aaaggggatc tttactcaat cccaggaaca cctccgtcac tttatactga cctgaaaggg
    16321 gatgcttttg ccttgcgttc tgactacgca atgcagattg acttcgaaca aaaagctcct
    16381 caattctcag tatcagagac acattgggct aaaacttggc ttcttcatga ggatgctcca
    16441 aaagtagaaa aaccagctgt gattgcaaat ctccatgata agatccgtga aaaaatggga
    16501 tttgcccatc tggctgacta ggaggaagga aatgtctgaa aaattagtag aaatcaaaga
    16561 tttagaaatt tccttcggtg aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt
    16621 ctttatcaac aagggagaaa ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac
    16681 tattggtcgt gctatcatcg gtctaaatga tacaagtaat ggagatatca tttttgatgg
    16741 tcaaaagatt aatggtaaga aatcgcgtga acaagctgcg gaattgattc gtcgaatcca
    16801 gatgattttc caagaccctg ccgcaagttt gaatgaacgt gcgactgttg attatattat
    16861 ttctgaaggt ctttacaatc accgtttatt taaggatgaa gaagaacgta aagagaaagt
    16921 tcaaaatatt atccgtgaag taggtcttct tgctgagcac ttgactcgtt accctcatga
    16981 attctcaggc ggtcaacgtc aacgtatcgg tattgcccgt gccttggtca tgcaaccaga
    17041 ctttgttatt gcagatgagc caatttcagc cttggacgtt tctgtacgtg cccaagtctt
    17101 gaacttgctc aaaaaattcc aaaaagagct cggcctgacc tatctcttca tcgcccatga
    17161 cttgtcggtt gttcgcttta tttcagatcg tatcgcagtt atttacaagg gtgttattgt
    17221 agaggttgca gaaacagaag aattgtttaa caatccaatt cacccatata ctcaagcttt
    17281 gctttcagcg gtaccaatcc cagatccaat cttggaacgt aagaaggtct tgaaggttta
    17341 cgacccaagt caacacgact atgagactga taagccatct atggtagaaa tccgtccagg
    17401 tcactatgtt tgggcgaacc aagccgaatt ggcacgttat caaaaaggac taaactaata
    17461 atggttttat aatttccatg tcaattttta tgggaattat aaaacttttt ttgttggact
    17521 gatttgaaaa actttgaaag cttcctgaaa gaattttcga aaaattttaa aaaattttga
    17581 aatattattg acaggtgatg aaaaaggtgg taggatagga aggatcaaaa aagaaagcag
    17641 aaaaagaaat gaataagaga caagccgtaa ctatgaatca aaacttttac tttagctact
    17701 ttagatagtg tttgtagaca tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta
    17761 tctatgtggc taagattttt gattgtggtc catatagatg aatatctaaa tggactagct
    17821 aagttgtaac ttgttaggtt atttcaagta cccgtttaga tagtatctag gcggtttttt
    17881 gttttatctt ttctgagaag gagtttcatt atgaaagttg ttcgaaaatc actagccccc
    17941 tcttggtagt ggggatcctc ttgacttctc tgatcagttt gcatcagttg aaggcagata
    18001 agaaaagaga tgtctttcgt atcggtattt cgcagtttat tacccaccag tccttagacg
    18061 ctactagaga aggatttgtg gatgagctgg ccaaacaagg ctatgttgag ggggaaaata
    18121 ttgagattga tttgcaaaat gcacagggag aacaaagaaa tctaaaaacg atttcccagc
    18181 aactagcaga atccagcgat gtcgttctag ccatcgcaag gccttctgct cagagcttgg
    18241 ccaatacgac gcaaacgaca ccagttatct tttcagctgt aacagaccca gtcagtgcca
    18301 agttggttga gtcaagagaa catcctgggg gcaatgtaac tgggacaagc gatcagtcat
    18361 cagatgccat ttcaacccaa atcaatttga taaagaaagt gttgccaaag gctaaaacga
    18421 ttggaatcct ctatactcag agcgagccca attcggttgt ttaaaatgat gaagctaagc
    18481 gacttctgaa agaaaaaggc tttaccgttg ttgaaaaaac aatcttggac agtaataacg
    18541 tcaaggcggc agcagagagt ttgatggcag aggtggatat ggtttttgtc ccaactgata
    18601 atatcatttc gtcaaccatg gaaacagtta agcaggtttc tattaaacac aaggttccag
    18661 tattcggtgg ttcaacagaa atgattgctg ttggtgactt gtataactac ggaaccaatt
    18721 atgaagaatt gggaagacag acagctcgca tgctgattcg tgttttaaaa ggtgagaaac
    18781 cagaaaatat agcagttgag ttgcctgaaa aactggaatt gcataccaat caagaaatgg
    18841 cagatgcatt gggaattgat attagtaagt tagaaggcaa ggaataagga ggattaagat
    18901 gaattttgtg ttatctagtt tatcagaagg tttgttgtgg tcgattgtgg cgattggggt
    18961 ctacttgact ttccgtattt tggatattgc ggatataact gctgagggag cctttcctct
    19021 gggggcagca gtcgttgtat cacagataca ggcaggggca aatccttggc ttgcgacttt
    19081 acttgctttg ctggcaggta tggtagcagg tcttgtatca ggaatgctcc acaccaagat
    19141 gaaaatccca gctctcttga cagggattgt gaccttgaca gggctctatt caatcaatat
    19201 taaaattatg ggcagtgtac ccaatctttc cttgggagat tctgcaaccg tctttaaaca
    19261 gttggcgagc ttgggtctga caaatgaagg agctgttttc tcacttagtt tagtctgtct
    19321 cttacttgtt tggtcttgac ccttttgatg aaaacagaga ttggtttggt cttgcgttcg
    19381 actggggata atatcccgat aagtgaggcc aatggagtca atgtagacac catgaagatt
    19441 gttggttaca tgatttcaaa cggtttgatt gccctatgtg gttccttgtt tgcccaaaat
    19501 gatggatttt cagatgtgac ttctgggaca ggaaccattg ttgttggttt gagctcggaa
    19561 gtcttgatac acgacttgac cattggaggc cgcttattat ccatcggaat cggtgctatt
    19621 gtttaccgtt tgattatttt aaatatctat gaaattccaa gtctagatca aaacttggta
    19681 cgtctcttta atgcaatctt gctcgctttg gttttatttg caccagaatt gcaaaagaga
    19741 ttaaagattc gtggtctgaa attgagaaat gaataggagg agaaagttat ggcaagtttg
    19801 ttaacacttg aaaatattca caagacattt gaagcaggga cggtcaatga gaaccatgtc
    19861 ctcaaaggat tagatttaga ggttgaagag ggagatttta tctatgtgat tggtggaaat
    19921 ggagcaggaa aatccacttt gatgaatatc ttggctggca atctatcggt ggacgaaggg
    19981 gaccttctac tggcagggaa atccattaaa aatctgagtg tcagaaagag agccaaggat
    20041 attgcccgtg tttttcaata tcctaagatg ggaacagctt ctcgtttgac gattgaggag
    20101 aatatgacta ttgccttgag acgtgggcaa aagagagggc ttggttgggg tgtgaaggag
    20161 aaggatagaa tccagttcca agaggccttg aaggagttga atattggtct tgaaaaccgc
    20221 ttaaaagtag atactcaata tctctcagga ggacaaagac aggctttgac cctagtcatg
    20281 gcagctctgg tgaaacccaa acttttactt ttggatgaac atactgcggc acttgacccg
    20341 aaaaccagtc aaatggtgat ggacttgacg caaaagattg tggagcacca tcagtggacg
    20401 actttgatga ttacccatga tatgaatcat gcgattgagt acggcaatcg tctcattatg
    20461 ctctatcaag gcaagatagt ggtggatgtc aagggagaag agaaaaagca tctgacagtt
    20521 gaagacctta tgcatctctt ccagaaaaat agtggccaaa gtctggtcag tgatgaatta
    20581 gttttgggat aaagaaaaag gctgagatct ggtgtctcag tcttttattt cttgcgtttt
    20641 gcaaaatcta caaatctaaa tttttctaac ttatggcgac tttcggtaaa ctgaaattgg
    20701 cgtccgtctt ggagatagac ttttgattta atcgaaacga cataagggtc tttgccaatg
    20761 tccatgagaa tcttgtctcg gtcgcttgag tggtcaatgg tgatttcctt ctgagcataa
    20821 tcaataagga gtttgaggcc attttctata taagaataga tagactgctc agcaatttgg
    20881 cgagtgagat ttgggatgag ttccatatcc agatagtccg tatccagaac ggataccaga
    20941 tcatccacca cacgctggcg gaccaccttc caaaccatcc gaaactctgg gaaaccggtt
    21001 atcagtgagg attttttatc aataataatc ttgtccagac tgaccacgtt ggttttagag
    21061 cgcagtccaa gttctttaac tagttcttgg tagctggtta ggttggatac agggaaattg
    21121 acggtttctt ctttgacgac ttgagaacct tgccctctta tctttttgat caatccttcc
    21181 tcttggagga gagacagggc ctttcggacg gtatcacgac tcacttgata ttgctccata
    21241 aggtcgtgct cgctaggaag gaaatctccg acagcgtaag tctcgttttg aatggtttct
    21301 tggatttgct taaataattg ttggtatttc ttcattttgc ctgctttaat aggtttttag
    21361 tctagtttaa tgaacacctg tatctatttt accatacaag tgctagaaaa tttacaaaaa
    21421 aacacccttt ttataccaaa caagttgcag acaagtttgg tatcgtttac aatatactta
    21481 tcaaatcaaa cttgctttga caagtataag gagaatcaaa tgggaaaatt tgaacaagaa
    21541 gccaaagatc tgcttcaggc aattggaggc aaagaaaatg tgactgccgt aactcactgt
    21601 gcgacacgga tgcgctttgt tttaggagat gataagaagg ctaatgttaa agctatcgag
    21661 tcaattccag ctgttaaagg aacttttaca aatgcaggtc aatttcaggt aatcattgga
    21721 aatgacgtgc ccatctttta taatgatttt acagccgttt caggtattga gggtgtttcc
    21781 aaagaagcag ccaagtctgc agctaagagt aatcaaaacg tggtccaacg tgttatgacc
    21841 actctggcgg agatttttac tccgattatt ccagccttga tagtcggagg attgatcctc
    21901 ggtttccgta atgtcttgga aggtgtccat tggtcgatgt tggatggcaa gaccatcaca
    21961 gaatcctctc agttttgggc aggtgtcaat cacttcctct ggttgcctgg tgaagctatc
    22021 ttccagttct taccagtagg gattacttgg tctgtttctc gtaagatggg aaccagccaa
    22081 attttgggaa ttgttctcgg aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg
    22141 gttgcttcaa cgccagcagc tgatatcgcg gcaaactggg tttggaattt tggctatttt
    22201 actgttaatc gtatcggtta ccaagcccaa gttatcccag ccttgcttgc aggtttgagt
    22261 ctgtcttatc ttgaaatctt ctggcgcaag catatcccag aagtcatttc tatgattttt
    22321 gtacctttct tgtcattgat tccagccttg attttggctc atactgtttt gggaccaatc
    22381 ggttggacaa ttggacaagg actttcatca gttgtcttgg caggtttaac tggtccagtt
    22441 aaagggctct tcggtgcaat ttttggtgcc ctctacgctc catttgtcat cacaggtctg
    22501 caccatatga ccaatgccat tgatacacaa ttgattgcgg atgctggtgg cactgcccta
    22561 tggccaatga ttgctctttc taatattgct caaggctcag ccgtgtttgc ctattatttc
    22621 atgcatcgcc atgatgagcg tgaggctcag gtttcacttc ctgcaaccat ttcagcctat
    22681 ctcggtgtta cagaaccagc tctttttggg gttaacgtaa aatatattta tccatttgtt
    22741 gctgggatga ctggttcagc ccttgcaggc atgttatccg ttacttttaa tgtaactgcg
    22801 gcttctattg gtatcggtgg tttgccaggt attctctcta ttcaacctca atacatgctg
    22861 ccatttgcag gaactatgct agttgcgatt gttgttccaa tgctcttgac tttcttcttt
    22921 cgcaaggctg gtctcttcac aaaaatagag ggcgatacga acttgcaggc agaattcgtt
    22981 gctcaagaag aagcagaatt tgtgaaccat gaaccagtag aacttacttc ggtagaaatt
    23041 atcagcccac taactggcca agtgaaagaa ttgagtcaag cgacggatcc tgtttttgca
    23101 tcaggtgtca tggggcaagg tctggtcatt gaaccaagcc aaggtgagtt gacctctcca
    23161 gttaatggaa cagtgacggt tcttttccct accaagcatg ccatcggcat tgtctctgac
    23221 gagggagttg aattgctcat ccacatcggt atggatacag taggtcttga tggcaaaggt
    23281 tttgaaagtc ttgtagtcca aggagatcac gttatagttg gccagcaact gattcgtttt
    23341 gatatggatg tcattaaggc tgcaggtctg gtgacagaaa ctcctgttat catcaccaac
    23401 caagatgctt atacagcgac tattactgga acttatccga caacgatcca agctggagca
    23461 tctctcatgg tcgctacacg aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc
    23521 tctatctgca acctcaaaat agtgttttga gcaacctgtg gctagcttcc tagtttgttc
    23581 tttgattttc attgagtata attgaaatag cacaaatagg gacggaagac tgcttcctcc
    23641 cttttatcag aaaaggagaa acagatgaca cttgataaag gaaaagtagt ctatcaaatc
    23701 tatccaaaat cttacaaaga caccactgaa aacggtattg gggatttccg tgggattatc
    23761 gaaaaaattc cctatttagc caaactaggt gtggatatgg tctggctcaa tccattctat
    23821 ccaagccctc aacgggataa tggttacgat atttcagatt atatggcagt ggatcctctt
    23881 tttggtgata tggctgattt tgaggaaatg gtgtgtatcg gtaaagagca caagattgac
    23941 tttatgctgg acatggtact taatcattgt tcgacagagc atgaatggtt tcagaaagcc
    24001 ctagctggtg ataagtatta tcaagacttt ttcttcatcc aagaccaacc aacagattgg
    24061 cagtctaagt ttggtggttc tgcatgggcg cctttcgggg atactgggaa atactatctt
    24121 cacctatttg atgagaccca ggctgacctt aactggcgca atcccaatgt ccgtaaggag
    24181 cttttcaagg ttgttaattt ctggcgcgac aagggtgtca aaggttttcg atttgatgtg
    24241 atcaatttga ttggtaagga cgaggtttca gtggactgtc ctgaaaatga agggaagcca
    24301 gcttatacag acaaacccat cgttcataac tatttgcgta tgatgaacca agccactttt
    24361 ggatctgacg atagctttat gacagttggg gaaatgtctt ctaccaccat ggaaaactgt
    24421 gtcctctatt cgtcgcctga tcgtcaggaa ttatccatga cctttaattt tcatcacctc
    24481 aaggtggact ataaggatgg acaaaagtgg accttggctc cctttgattt tgaagagttg
    24541 aagagtcttt accatagttg gggtaaggaa atgagtgata aagacggttg gagtgccctc
    24601 ttttggaaca atcacgatca accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc
    24661 cgcaaggaag gagccaccat gctagcagcc agcattcacc tgtcacgtgg gacaccttat
    24721 atctacatgg gtgaggaaat cgggatgatt gacccagact atgattctat ggctgattat
    24781 gtggatgtcg aatcgcttaa tgcctatcag atgctcttag aagaaggaaa gagtcagcaa
    24841 gaagccttcc agattattca agctaagtcg cgtgataatt cacgcattcc catgcagtgg
    24901 gatgcttcgg aaaatgcagg attttcaaca ggcactcctt ggttgaaagc tggtaaatcc
    24961 tataaataca tcaatgtaga aaatgaaatc cagggtccga tttttacctt ctatcaagac
    25021 ttgattcgac tgcgtaagga aatgccaatc atttcagaag gaagttacaa accagccttt
    25081 gaagatagca aacaagtcta cgcttttgaa cgccagtttg aggatcaaaa gttactagtg
    25141 ctcaataact tttatgctaa agaagtggaa atcgacttgc cagcagtcta ccaaaatgga
    25201 cagattttga tatcaaacta tgaagatgca gaagtgtctg agaaaattct actcaaaccc
    25261 tatcaaacac tggctattta tgtaaattaa tactcttcga aaatctcttc aaaccgtgtc
    25321 agttttatct gcaacctcaa agcggtgctt tgagcaacct gtggctagct tcctagtttg
    25381 ctctttgatt ttcattgagt ataaacttag caaggagacc tctttttcag aaaagcaggg
    25441 ttctttttgc tgtctattcc atccctgaaa gtgtagaaca aactggtcag ggtggctagt
    25501 ttgtggtata atgaaaggga ctcaaaaaga aacaggagaa aaatgatgga tttactttta
    25561 gcaattgtat tgattgtgct agcttttcta ggaggagctc ttggaggaat gtacttggtt
    25621 cgtaagcaaa tcgaaaaaga atttgctgac aacccacgtt tgaatgctga agcagttcgt
    25681 actcttttga gtgcaaatgg tcaaaaacca agcgaagcta aggtacaaca agtttaccac
    25741 caaatcatcc gccaacaaaa ggcagccctt gctaacaata aaaagaaaaa ataaataagg
    25801 aaaagtctgg gatgaaagtt ccagacttct cactatgttg gttatggttt agggatgaga
    25861 ctttttcctt gcattctatt gatatttgat tatgattaag agagaggtag ttgacattct
    25921 atcaagctgt cggtcagttc gttcagtaca aggaatcata atgaacgatc aatcagaaaa
    25981 aagactagaa agaagactgt atggataatc gaccaattgg ttttttggat tcgggtgtcg
    26041 ggggcttgac cgttgtgcgc gagctcatgc gccagcttcc ccatgaagaa atcgtctata
    26101 ttggagattc ggcgcgggcg ccctatggcc cccgtcctgc tgagcaaatt cgtgaatata
    26161 cttggcagct ggtcaacttt ctcttgacta aggatgtcaa aatgattgtc attgcttgta
    26221 acactgcgac tgcggtcgtc tgggaaaaaa tcaaggctca actagatatt cctgtcttgg
    26281 gtgtaatttt gccaggagct tcggcagcca tcaagtccag tcaaggtggg aaaatcggag
    26341 tgattggaac gcccatgacg gtacaatcag acatataccg tcagaaaatc catgatctgg
    26401 atcccgactt acaggtggag agcttggcct gtcccaagtt tgctcccttg gttgagtcag
    26461 gtgccctgtc aaccagtgtt accaagaagg tggtctatga aaccctgcgt cccttggttg
    26521 gaaaggtgga tagcctgatt ttgggctgta ctcattatcc actccttcgc cctattatcc
    26581 aaaatgtgat ggggccaaag gttcagctca tcgatagtgg ggcagagtgc gtacgggata
    26641 tctcagtctt actcaattat tttgaaatca atcgtggtcg cgatgctgga ccactccatc
    26701 accgttttta cacaacagcc agtagccaaa gttttgcaca aattggtgaa gaatggctgg
    26761 aaaaagagat tcatgtggag catgtagaat tatgacaaat aaaatttatg aatataagga
    26821 tgaccaggac tggtatgttg ggtcttatag tatttttggt ggcgttaaca gtttgagcga
    26881 ctatcagaca gattttcctc tgtttgaatt ctccaaaata tttggagatg aagagtatgg
    26941 tttcccgctt tcagttactg ttttacgcta tggttctacc taccgtttgt tctcctttgt
    27001 ggtagatatg cttaatcaag aaatgggacg aaacttggaa gttattcaac gtcatggggc
    27061 cctgctcttg gttgaaaatg ggcaactctt gtatgtagaa ttgcctaaag aaggggtcaa
    27121 tgttcatgat ttctttgaga caagcaaggt cagagaaacc ttgttgattg cgactcgtaa
    27181 cgaaggcaaa accaaggaat tccgagctat ctttgataag ttaggctacg atgtggaaaa
    27241 tcttaatgac taccctgacc tgcctgaagt agcagaaaca ggtatgacct ttgaagaaaa
    27301 tgcccgcctt aaggcagaaa ccatttctca attaacgggt aagatggttt tggcagatga
    27361 ttctggtctc aaagtcgatg tccttggtgg cttaccaggc gtctggtcag ctcgtttcgc
    27421 aggtgtggga gcaactgacc gtgaaaataa tgccaaactc ttgcacgaat tggccatggt
    27481 ctttgaactc aaggaccgct cggctcagtt ccacacaacc ctagtcgtag ccagcccaaa
    27541 taaggaaagt ttagttgttg aagcagactg gtcaggttat attaactttg aacctaaggg
    27601 tgaaaatggc tttggctatg atcccctctt ccttgtagga gagacaggtg agtcatcagc
    27661 tgaattaacc ctagaagaaa aaaatagtca atctcaccgt gccttagccg ttaagaaact
    27721 tttggaggta tttccatcat ggcaaagcaa accatcattg taatgagcga ttcccatggc
    27781 gatagcttga ttgtggaaga agtccgtgat cgctatgtgg gcaaagtcga tgccgttttt
    27841 cataacggcg attctgaact acgtccggat tctccacttt gggagggcat ccgcgttgtt
    27901 aaagggaaca tggacttcta cgccggctac ccagaacgtc tggtgactga gcttggttcg
    27961 accaagatta tccaaactca tggtcacttg tttgacatca atttcaactt tcaaaagttg
    28021 gactactggg ctcaggagga agaggccgct atctgcctct atggtcactt gcatgtgcca
    28081 agtgcttggt tggaaggcaa gatcctcttt ctaaatccag gttctatcag tcaaccacga
    28141 ggtaccatca gagaatgtct ctatgctcgt gtggagattg atgatagtta cttcaaagtg
    28201 gactttttga cacgagatca cgaggtgtat ccaggtttgt ccaaggagtt tagccgatga
    28261 ttgccaagga gtttgagact ttcttgttgg ggcaggagga aacttttttg acccctgcta
    28321 aaaatctagc tgtgttgatt gatacccaca atgcggatca tgcgaccctc ttgctcagtc
    28381 agatgaccta tacccgtgtt cccgttgtga cagatgaaaa acagtttgtt gggacgattg
    28441 gactcagaga tattatggct tatcagatgg agcatgactt gagccaagaa atcatggcgg
    28501 atacggatat cgttcatatg acaaaaacgg acgtagcggt tgtttcgcct gatttcacca
    28561 ttacggaggt cttgcacaag ctagtagatg agtccttctt accggttgtg gatgcagagg
    28621 gtattttcca agggattatt acgcgcaagt ccatcctcaa ggccgttaat gccctcttgc
    28681 atgactttag taaggaatat gagattcgat gccaatgaga gacaggattt cagccttttt
    28741 agaggaaaag cagggcttgt ctgtcaattc caaacagtcc tataagtatg atttggagca
    28801 atttttagac atggtaggtg agcggatttc tgagaccagt ctcaagattt accaagccca
    28861 gctagccaat ctaaaaatca gcgcccagaa gcgaaagatt tcggcctgta accaatttct
    28921 atactttctc tatcaaaaag gagaggtgga cagcttttac cgcttggaat tagccaaaca
    28981 agctgaaaag aagacggaaa agccagagat tctataccta gactcttttt ggcaggaaag
    29041 cgaccatcca gagggccgct tgctagcgct cttaatccta gaaatggggc tcttgcccag
    29101 tgagatttta gccatcaagg ttgcggacat caatctggat tttcaggtgt tgcgaatcag
    29161 caaggcttcc caacagagga ttgtcaccat tcccacggcc ttgctttcag aattggaacc
    29221 cttgatgggg cagacctatc tttttgaaag aggagagaaa ccctattctc gtcagtgggc
    29281 ctttcgtcag ttagaatctt ttgtcaagga gaaaggtttt ccatccttat cagctcaagt
    29341 cttacgtgaa cagtttattc taagacaaat agaaaacaag gtcgatttgt acgaaattgc
    29401 aaaaaaatta ggattaaaaa cagtcctgac cttagaaaaa tatagataat ggatattaaa
    29461 ttaaaagatt ttgaaggacc cctggacttg ctcttgcatc tggtttctaa gtaccagatg
    29521 gatatctacg atgtgcccat tacggaagtc atcgaacagt atctagccta tgtctcaacc
    29581 ctgcaggcca tgcgtctgga agtgacgggt gagtacatgg tcatggctag tcagctcatg
    29641 ctgattaaga gtcgtaaact ccttccgaag gtagcagaag tgacagactt gggggatgat
    29701 ctggagcagg acctcctctc tcaaatcgaa gaatatcgca agttcaagct cttgggtgag
    29761 cacttggaag ccaagcacca agaacgggcc cagtattatt ccaaagcgcc gacagagttg
    29821 atttacgaag atgcggagct tgtgcatgac aagacgacca ttgacctctt tttggctttt
    29881 tcaaatatcc tagccaagaa aaaagaggag tttgcacaaa atcacacgac tatcttgcgg
    29941 gatgagtata agattgagga catgatgatt attgtgaaag aatccttgat tggacgagat
    30001 caattgcgct tgcaggattt gttcaaggaa gcccagaatg tccaagaggt catcaccctc
    30061 tttttggcaa ccctagagtt aatcaaaacc caggagctga tcctcgtgca agaggagagt
    30121 tttggagata tctatctcat ggaaaagaag gaagaaagtc aagtgcctca aagctagact
    30181 tgatagagag gaaagatgag tactttagca aaaatagaag cgctcttgtt tgtagcgggt
    30241 gaagatggga ttcgggtccg ccagttagct gaactcctct ctctgccacc gacaggcatc
    30301 cagcaaagtt taggaaaatt agcccagaag tatgaaaagg acccagattc cagtttggct
    30361 ttgattgaga caagtggtgc ttatagattg gtgaccaagc ctcaatttgc agagattttg
    30421 aaggaatact ctaaggcgcc tatcaaccag agcttgtctc gggctgccct tgagaccttg
    30481 tccattattg cctacaaaca gccgattacg cggatagaaa ttgatgccat ccgtggagtt
    30541 aactcgagtg gagccttggc aaagttgcag gcttttgacc tgataaagga agacgggaaa
    30601 aaggaagtat tggggcgccc caacctctat gtgactacgg attatttcct agattacatg
    30661 gggataaacc atttagaaga attaccagtg attgatgagc ttgagattca agcccaagaa
    30721 agccaattat ttggtgaaag gatagaagaa gatgagaatc aataagtata ttgcccacgc
    30781 aggtgtggcc agtaggagaa aagcagaaga gctgatcaag caaggtttgg tgacggttaa
    30841 cggccaagtg gtgcgtgaac tagcaaccac tatcaagtca ggcgacaagg tcgaagttga
    30901 aggtcaacct atctacaacg aagaaaaggt ctattatctg cttaacaaac cacgcggtgt
    30961 catttccagt gtgacagatg ataagggtcg caagacggtt gtcgacctct tgcccaatgt
    31021 caaagagcgt atttaccctg tgggtcgttt ggactgggat acatcaggag tcttgatttt
    31081 gaccaatgat ggggacttta cagacgagat gattcaccct cgtaatgaga ttgacaaggt
    31141 ttatgtcgcg cgtgttaaag gtgtggccaa taaggacaat cttcgcccct tgacccgtgg
    31201 tcttgagatt gatggtaaga aaaccaagcc agctgtttat gaaattctca aagtggaccc
    31261 agtcaaaaat cgctctgtgg tgcagttgac catccatgaa gggcgtaacc atcaggttaa
    31321 aaagatgttt gaagctgttg gtctccaagt agataagttg tctcggactc gtttcggaca
    31381 cctagacttg acaggactcc gtccaggaga atcccgtcgt cttaataaaa aagaaatcag
    31441 ccaactacac accatggctg taactaagaa ataatgaaac gaattttaat agcgcctgtg
    31501 cgcttttacc aacgttttat ctcaccagtc tttccaccct cttgtcgctt tgatctgact
    31561 tgttccaact acatgattca ggctattgaa aaacatggtt ttaagggagt attgatgggc
    31621 ttggctcgga ttttacgttg tcatccctgg tcgaaaacag gtaaggaccc cgttccagac
    31681 cacttttccc ttaaacgaaa tcaagaaggg gaatgaggtg gggtaaatag atttcaaaat
    31741 gataaaaacg catcctatca ggtttgagtg aacttgatag gatgcgtttt agaatgtcaa
    31801 aattttatac tcttagaaaa tctcctcaaa ccgcatcagc tttcatctgc aacctcaaaa
    31861 cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
    31921 taaattgagt ttgaagtggc ttatttcaaa gctttttgta tgtcttcaat catgagtttt
    31981 gttgattcaa gtccgcctcc gcttagatac cagaggtctg gtgttagttg gataatctta
    32041 ccatttttag cagcaggtgt ttcagcgata agggcatttt ctaggacacc gtcgttgcta
    32101 gagttgtccc caccgatggc aagggtacgg ttgatgacaa agaggatgtc agggttgatt
    32161 tctttgacac tttcaaagct gacttcttgt ccgtggcgtg agtcttcaaa tgttgtatca
    32221 gttggtttga atttcaaggt ttggtacaag aaagagaaac gagatttggc accaaaggct
    32281 gccatttttc cttcattaag gaggatcgca agggcttttt tgtcagagct ttcattttta
    32341 gtagcgattt cttggatgct cttgtctagc ttggccaatt cttccttggc tttctgtgta
    32401 ccagtttcgc cgaaggcact tgctaaggat tcgatattag ccttggtaga agtccagtag
    32461 tcgtccttgc ttgcttggaa gagaacggtt ggggcgattt ctttgaattt gtctacgaat
    32521 ttttgtgtac gtggtgaagc gataatcaaa tcaggctcaa gggcggcgat agcttctaaa
    32581 tcaggttctt tcatagaacc aacatttttg acagttccca ctaggtcttt tagataagtc
    32641 ggaacagttt ttgtaggcat tccgacgata tttttttcaa atcctaaagc gcgaatagta
    32701 tccgcagcgc cgaggtcaaa ggtcacaatc ttttcaggaa ctttggaaag tttgacctcg
    32761 tccagtgaac ttttaatggt tacctctgtt ggagcagagc tactggtctc tgtctgacta
    32821 gtgcttgagt ttgtactaca tgcaccaagt aggagcaaga agctggccac tagggcagtg
    32881 aaataaagtt taagggatgt tttcataatt tctccttttt aaaatgtgat aacgatttag
    32941 ggagtctctt aatcttattg actaagagac tgaaggttct ctaacttgag cttttatgtt
    33001 actagctata gatacagatc tttttgtcat tgatatcagc tagcgtgatg ggaatctcat
    33061 aaagttgact gagcaggtca gcctgcatga tttgatcggt tcttcccttg ctaaagacct
    33121 ggccgtcctt gaaggcgaca atttcatctg catactgact ggccatgttg atatcgtgga
    33181 ggacgatgat aatggtcttg ccgagttcct ccaccagtcg tcgaagaatc tgcatcatgc
    33241 tgacgctttg cttgatatcg agattgttga gtggttcgtc cagcaagata aagtccgtat
    33301 cctgggccag taccatagcg ataaagacgc gctggagttg cccccctgac aggctattga
    33361 tgtagcggtc ttttaagttg gtcagttcca aatagttcag agtttctcgg attttttccc
    33421 agtcttctga tctaagtcga cctcggctgt agggaaaacg tccaaaactg accagttctt
    33481 caacagtcaa tttggcttgg taattgattt tctgttttag gatggttagt tcttgggcca
    33541 gttcttgcga attccagctc tcgatttcac gtcctttgat actgagaact ccctgatctt
    33601 tcttggttag tctgctcatg atggagagga gagtcgattt tccagcacca tttggaccaa
    33661 taaaggctgt cagtttttga ggactgactt caagcgaaat gccttgcaaa atatcctgtt
    33721 tttgaatgga tttgtcaatg ttttccagtt tcactgacga gacctcctat atagtaagat
    33781 aaagaataag aagccaccca cactctcaat gatcatactg atacgaattt ccagtgcaaa
    33841 gactcgttca atcaaggctt gccccaaggt taaactaata aatccaacca gaatggccac
    33901 tataaagagt aacttgtgct gatagtcttt gacaatcagg taggtgaggt tggccagcat
    33961 aaagccgaag aaggccatag gtcctaccaa ggcagtggcc gttgaggtca aaagcacgat
    34021 tccccagagg agctctttct gttctttttc aacatcgagt cccaatatct gagccgtttc
    34081 tctttgcagg tgcaagacat ctagaacgac tgcttttcga aagaaaaaga ttgtcaaagc
    34141 gaggatgatc agagaaccga tggctaggat ggaagtgtta agatgttgaa aggaggcaaa
    34201 aagactattt tgcagtttat cgtattcgtt tggatccatt aggacttgaa ggaaggtgct
    34261 gatatttcga aagagacttc tgagcgctag acagatcagc aggatgaaga ccaggtcttg
    34321 cttcatcagt gtcttcaagt aaccttgtaa ggcgagaaag aagagggact ggacaagaag
    34381 taagactagg aattctaaga taggggattt gccaagttga agaaacttgc tttcaaaaac
    34441 cagtagtagg gtttgtagta ggacgtagaa ggattcaatt cccaaaatac taggcgtcag
    34501 gaagcgattt tccgtcaggg tttgaaaact aatggtcgaa atcccagtcg cgatggctac
    34561 caagagataa acgatgatct tttgggaacg caacttccaa gcaaaggctg acaagtgagt
    34621 gatgggccaa aagtagagaa gacaagctcc gatggcaaga ataatgagaa tccagaagag
    34681 cttggtatgt ttgcttttag tctgcatctt ttcgtccccc tctccagaga agtaggataa
    34741 agacgagact accgatgatt cctagcaaga gactgacaga caactcatag ggcctaatca
    34801 gaactcggga taggatatcg caagccagaa ctagattggc accaaccagt gcgaccatga
    34861 gtttggtttg acttagatta tctccatagc gcttgcgaac aagattggga acgataactc
    34921 cgagaaatgg taggccaccc acggtaatca tggtgacgct tgtcgttagc gccaccagaa
    34981 agagggccag tttttcaagt agggagtagg aaatccccaa actctcgctg gtttctttcc
    35041 ctagattcat gatggtgaag gtttgggata atttccaaac ggttatcagg atgatgaggc
    35101 ctaagaagag ccactcatac tgatgggtct gaatcatgga gaaggagccc tgggtccagg
    35161 cagtcatact ctgaaccaga ttgaaacgat aggcgataac ttctgtgact gagccgataa
    35221 tcccgctata gatgatccca atcagaggca acatccacct ttcctttaca gtaaaaatgg
    35281 tcataaaggc taggaagaag agggtgaata cgatggatga aacaaaagcg aagagcatct
    35341 tttgggtcag actagccgat ggaaagacaa aaaggctcag caccattccc agtttggcgg
    35401 cttcagtcgt tccaactgta ctcggtgcag caaactgatt ttgggtaata gtctgcatga
    35461 gaaggcctgc catactcata ctagaggcag tcaggagaat actgatagtt cttgggagac
    35521 gggactcttg aaagaggagc caggtctgct ggtcgaaatc aaatagcttt ccccatgaaa
    35581 aatcactggt cccaatgcta atagagagaa agactaggag tagaagtaag ccaattaaat
    35641 aatgagaaag tttcataccc cgtcctttca tgtagatttg gtatcgaaag atacctgcgg
    35701 atataaatgt aacattattt ttctaatctg tcaataaaat ttctgacaat ttaataaata
    35761 caacaaggag agagcaacaa gactttctcc tttgttatcc tattctaaaa tgtttttacc
    35821 ttaatctgat aaaataatat cttcgaggga gtagctagcc gtccaatcaa gatattgttt
    35881 agcttttgaa gcatctgcta ggacactggc tgggtcacta gcacgtcgag caacaatctc
    35941 gtgtgggatt ttttaattta gtaattcttc agcagtttta aagatttctt tgatagtata
    36001 gcctttttta gttcctaagt taaagatttg agaagaactg tcttcttgaa ataggtagtt
    36061 cattccttta acatgagcct atgcaaggtc caagacataa atgtaatctc gaatacatga
    36121 accgtcacgt gtatcgtagt catctccaaa tatttttaag ctatcatttt gtcccaatgc
    36181 ggtcttgttg atatttggaa tgatgtgagt tggatttttc acacgcagac cgtttgaagc
    36241 atccatttca gccccagcaa cattaaagta acggaaaata acatatttcc agtcgtagcg
    36301 attggccatc cagtaaatca ttcgttcgcc catcagtttt gtctctgcat aagggttgac
    36361 agggtcgagc agggtatctt cagtcgccgg cttgtcaata cagttatttc catagagaga
    36421 agcagtcgaa gagaacatga ttttttgaat gccaacttca gataagactt tgagaacttg
    36481 gttcatacca gcaacgttgg cagtgaagta tttacttgga ttttcaatac tttcgctcac
    36541 aacaatttca cctgcataat ggaggacagc atcaatctga ttttcttcta agtaagcctt
    36601 taaggcgcta gcatcataaa catccagttc tttaaagcta gcacgactat ccacagccgc
    36661 tcgatttcct gtggagagat tatcgaggac atgcacctta taaccagcat ttaaaagagc
    36721 tttaacggta tgggagccaa tgtagctagt cccacctgta acaagaattg ttttggtcat
    36781 gattttttcc ttttctagtt ttgtactata gtaaattgaa ataagatatg aacaactcta
    36841 ttaggaaagt caaattaatt tctagaaatg ttttagcagc tacagcgtac tattccaaac
    36901 tcaaccaact atatatttaa agaaagaaga aagggaagtc aactattttc tgtaaatttc
    36961 atgaaaaatc caaacaactt tgatggtgta ttgttttttt gtttggaaat aaatattcga
    37021 gttaattttg gaatgtttac tagattttgc actacatgca agagaatact atccttttct
    37081 aagatagagc aggactaaga tactaactta gaaatccacc ttcccactat ccttctccta
    37141 taaaaagtgg taaaatggat gaaagaaaga aggaactgaa atgacaacat tattttcaaa
    37201 aattaaagaa gtaacagaac ttgctgcagt ctcaggtcat gaagcgcctg tccgtgctta
    37261 tcttcgtgaa aagttgacac cgcatgtgga tgaagtggtg acagatggct tgggtggtat
    37321 ttttggtatc aaacattcag aagctgtgga tgcaccgcgc gtcttggtcg cttctcatat
    37381 ggacgaagtt ggttttatgg tcagcgaaat caagccagat ggtaccttcc gtgtcgtaga
    37441 aatcggtggc tggaacccca tggtggttag cagccaacgt ttcaaactct tgactcgtga
    37501 tggtcatgaa attcctgtga tttcaggttc tgttcctccg catttgactc gtggaaaggg
    37561 gggaccaacc atgccagcca ttgccgatat cgtttttgat ggtggttttg cggacaaggc
    37621 tgaggcagaa agttttggca tccgtcctgg tgataccatt gtaccagata gttctgcaat
    37681 tttgacagcc aatgaaaaaa atatcatctc aaaagcttgg gataaccgct acggtgtcct
    37741 catggtaagc gagctagctg aagctttatc gggtcaaaaa ctcggcaatg aactctatct
    37801 gggttctaac gtccaagaag aagttggtct gcgtggcgct catacctcta caaccaagtt
    37861 tgacccagaa gtcttcctcg cagttgattg ctcaccagca ggtgatgtct acggtggtca
    37921 aggcaagatt ggagatggaa ccttgattcg tttctatgat ccaggtcact tgcttcttcc
    37981 agggatgaag gatttccttt tgacaacggc tgaagaagct ggtatcaagt accaatacta
    38041 ctgtggtaaa ggcggaacag atgcaggtgc agctcatctg aaaaatggtg gtgtcccatc
    38101 aacaactatc ggtgtctgcg ctcgttatat ccattctcac caaaccctct atgcaatgga
    38161 tgacttccta gaagcgcaag ctttcttaca agccttggtg aagaaattgg atcgttcaac
    38221 ggttgatttg attaaacatt attaaaccat aagggaggtg gtagggatgg cagaaccaaa
    38281 cctagaaagc cttataaaag atctttacaa tcatgctcga catgatttga gtgaagattt
    38341 agttgctgct ctcctagaga ctgctaaaaa actgcctact acaaatgagc aattgcaggc
    38401 agttcgtctc tcaggcctgg tcaatcgtga attgctccta aatcccaaac atccagcacc
    38461 tgagttgctc aacttggctc gctttatcaa aagagaagaa gccaagtaca gaggaactgc
    38521 gacttctgcg cttatgtatg aggaactctt taaaatgctt tgattccatt gtggatcaaa
    38581 gcattttttg taagatctat ctcgtgagcg ttcaaatagt agtaacaagg aatcatgaga
    38641 agtcagccga gcccatagta gtgaagaaac ttctgtaatg gaagtggagc gaagtgagga
    38701 atcgtcaaac ggtaggggat aggctgtttg aagggtgcta cgaaaaagat agggtaaggt
    38761 gaaattatag cggaatgaaa taagatatga acaaattgat tgaggaaatt aaatgaattt
    38821 atagaaatct tttagcagtc atggtgtcct attccagttt cgaaatgcta taaatacgaa
    38881 caaattgatt gggaaattca aatcgctttc tatcaatgtt ttagaagata cagtgctcta
    38941 gtctaacttc aatatactat aaaagaacag atggaagcaa ttatgattta cttctatctt
    39001 taaaataaat ggtctgatag gaaaaatgtg tcccctcata aaatatagga tagtacgaat
    39061 ggaaggcttt tgtagactgg aggacgaagg agtttagaaa ctctcgttaa aagttagttg
    39121 agccggagta tggtggtgtg gataattatc aaaaattatt tctaaatcga aatagttgac
    39181 agttagaacg atgagtgtta caattgtttt attcatttcg atatcgaaat aaattggagg
    39241 tgttatgaaa gatggtcatt tgctagccca tcatattcgt ttgttgaatg ggcggatttt
    39301 tcaaaagtta ctgagtcaag atcctgaggc tctttatagg ggtgaacagg gcaagatttt
    39361 agcggtttta tggaatagtg aaactggctg cgcaactgcg acagatatcg cgcttgcgac
    39421 tgggcttgcg aataatacgc tgacgactat gataaaaaag ctagaggaac aaaagcttgt
    39481 aattgttagt ccgtgtggaa aagacaagcg taagaagtat ttagttttaa cggagttagg
    39541 caagtcccag aaagaagtgg ggcatcgtgt cagtcagaaa ttggatacta tcttttacaa
    39601 aggattttca gaggaagaaa ttcaccaatt tgaaggtttt caagaaagaa ttttggcgaa
    39661 tttgaaagag aagggaaatg aggtttagaa tatgtcacaa caagtgaaaa atgctcacaa
    39721 cctatacatc catgccattc aagacggacg agttgctgag gctcaagccc agtctgtagg
    39781 ggatacctat atccaacatt cgacaggtgt tcctgacggg aaagaaggat ttgcagcctt
    39841 ctttgcagat ttctttgagc gtcatccaga gcgtcagatt aagattgtcc gcaccattga
    39901 ggatggcaat ctggtctttg ttcatgttca tcaatatctg aatggtggag aagctcaatg
    39961 ggtgacgacg gatactttcc gtgcggatga gaatggtcgt attgttgagc attgggatgt
    40021 cattgactac tatcgaacac ctgaaaatga ccaactagat caaatttttg gagattttga
    40081 aatcaaggat ttggataaga aagcagaaaa taaaaagctg gttcgccgtt tcttgacaga
    40141 aattttccaa aatggggagc tagagcagtg gagtgattat gtggcagacg atttgattca
    40201 gcataatcat gagattggac aaggaagtgc tgcttataaa aactatgtgg ctgaatatag
    40261 tgtcactttt gactttgttt tccaactctt aggacaagga aactatgtgg ttagctatgg
    40321 tcagactcag attgatggcg ttgcttatgc ccagtacgat atcttccgtt tagagaacgg
    40381 gaaaattgtg gagcattggg ataataagga agtcatgcct aaggtagaag acttgactaa
    40441 tcgagggaag ttttaaattg aggacaaaga atgattgaat acaaaaatgt agcactgcgc
    40501 tacacagaaa aggatgtctt gagagatgtc aacttacaga ttgaggatgg ggaatttatg
    40561 gttttagtag ggccttctgg gtcaggtaag acgaccatgc tcaagatgat taaccgtctt
    40621 ttggaaccaa ctgatggaaa tatttatatg gatgggaagc gcatcaaaga ctatgatgag
    40681 cgtgaacttc gtctttctac tggttatgtt ttacaggcta ttgctctttt tccaaatcta
    40741 acagttgcgg aaaatattgc tctcattcct gaaatgaagg ggtggagcaa ggaagaaatt
    40801 acgaagaaaa cagaagagct tttggctaag gttggtttac cagtagccga gtatgggcat
    40861 cgcttaccta gtgaattatc tggtggagaa cagcaacggg tcggtattgt ccgagctatg
    40921 attggtcagc ccaagatttt cctcatggat gaaccctttt cggccttgga tgctatttcg
    40981 agaaaacagt tgcaggttct gacaaaagaa ttgcataaag agtttgggat gacaacgatt
    41041 tttgtaaccc atgatacgga tgaagccttg aagttggcgg accgtattgc tgtcttgcag
    41101 gatggagaaa ttcgccaggt agcgaatccc gagacaattt taaaagcgcc tgcaacagac
    41161 tttgtagcag acttgtttgg aggtagtgtt catgactaat ttaattgcaa cttttcagga
    41221 tcgttttagt gattggttga cagctctatc tcaacatttg cagttgtcac ttttgacctt
    41281 gttactagct attttgcttg cgattccctt ggctgttttt cttcgctatc atgagaagct
    41341 ggccgactgg gtcttgcaga ttgcaggtat tttccagacc atcccgtctc tggccttgtt
    41401 ggggctcttt atccctttga tgggaattgg gaccttgccg gctttgacag ctctagtgat
    41461 ttatgcgatt tttccgattt tacaaaatac tattactggg ctgaagggaa ttgatccgag
    41521 tcttcaagag gctgggattg cctttgggat gaccagatgg gagcgtctca agaagtttga
    41581 aattccactt gccatgcctg ttatcatgtc tggaattcgg acggcagcgg tcttgattat
    41641 cggtacggct accttggcga ccttgattgg ggcaggggga ctgggttcct ttatcctgtt
    41701 gggaattgac cgtaataatg ccagtttgat tttgattggg gccctttctt ctgcagtgct
    41761 agctattgcc tttaacttcc tactaaaagt aatggaaaaa gcgaaattgc ggacgatttt
    41821 ctctggtttt gccttggtgg ctttattact gggtctgtct tatagtccag ctcttttggc
    41881 tcaaaaagag aaggaaaact tgattattgc tgggaaaata ggcccagaac cagaaatttt
    41941 ggctaatatg tataagttgc tgattgaaga aaataccagc atgactgcga ctgttaaacc
    42001 gaattttggg acgacaagtt tcctttatga agctctgaaa aaaggtgata ttgacattta
    42061 tcctgaattt accggtacgg tgactgaaag tttgcttcaa ccatcaccca aggtgagtca
    42121 tgagccagag caggtttatc aagtggcgcg tgatggcatt gccaagcagg atcatctagc
    42181 ctatctcaaa cctatgtctt atcaaaatac ctatgctgta gctgttccga aaaagattgc
    42241 tcaagaatat ggcttgaaga ccatttcgga tttgaaaaaa gtggaagggc agctgaaggc
    42301 aggctttacg cttgagttta acgaccgtga agatggaaat aagggcttgc aatcaatgta
    42361 tggtctcaat ctcaatgtgg cgactatgca gccagctctt cgttatcagg caattcagtc
    42421 aggggatatt caaatcacgg atgcctattc gactgatgcg gaattggagc gttatgattt
    42481 acaggtcttg gaagatgaca agcaactctt cccaccttat caaggggctc cactcatgaa
    42541 agaagctctt ctcaagaaat acccagagtt ggaaagagtt cttaatacat tggctggtaa
    42601 gattacagaa agccagatga gccagctcaa ctaccaagtc ggtgttgaag gcaagtcagc
    42661 aaagcaagta gccaaggagt ttctccaaga acaaggtttg ttgaagaaat gatgggacag
    42721 agactttaaa catactgaac tcaacttcct taaacgacta gataaaagaa tgctcagaca
    42781 atttcgtctg ggctttttga tgtgagaatg actgaatgtc acttaaaatg gaaagaaaga
    42841 gaaaattttc atgattttct aaaattttac tgtaaagaca gttgactatt cataaaatag
    42901 gtgtataata ttttgtgaac tacttaacaa ataagaggtt tcagctcatg tcgactaagg
    42961 ttagaaatct tgtgtatagg cagttcatta tctaatagag cgttgcgtcc gaaagtctat
    43021 ccagacacgg ctctttaaaa acaaaaggag aaatgatgca tacttatttg caaaagaaaa
    43081 ttgaaaatat caaaacaacc ctaggtgaaa tgtcaggtgg ttaccgtcgt atggttgcgg
    43141 ctatggctga tttaggattt tcaggaacta tgaaggctat ctgggatgac ctctttgccc
    43201 atcgtagttt tgcccagtgg atttatttgc tggttttagg aagttttcct ctctggctgg
    43261 agttggttta cgaacatcgt attgttgact ggattgggat gatttgtagc ttgacaggga
    43321 ttatctgtgt aatctttgta tcggaaggtc gagcaagtaa ttatcttttt ggcttgatta
    43381 actctgttat ttaccttatt ttggccctac agaaaggctt ttatggtgag gtgctgacga
    43441 cactttactt cacagtcatg cagccaattg gacttctagt ttggatttat caggcacagt
    43501 ttaagaagga aaagcaggag tttgtcgcgc gtaaactgga cggcaagggc tggacaaagt
    43561 atctttccat tagtgtgctt tggtggttgg cctttggctt catttatcag tctattggtg
    43621 ccaatcgtcc ctatcgtgat tcaatcacag atgcaaccaa tggggtaggg caaatcctca
    43681 tgacagctgt ttaccgtgaa cagtggatat tctgggcggc taccaatgtt ttttcaatct
    43741 atctctggtg gggagaaagc ctgcaaattc aagggaaata tctaatttat ctcattaaca
    43801 gtctagttgg ttggtatcaa tggagcaagg cagctaagca gaatactgat ttacttaact
    43861 aggaaaagat gtttgaaagt gctgttttga gatttcgatt aaaacagata tagttgataa
    43921 tcaaggattt atagtatgaa aaagaggatc ggcgggtcct cttttgttgt tgaaaagata
    43981 aaaaactcag taacctagaa ataagacaac tgagctttac tctatattca atttttagga
    44041 atgagaaggt ctagataaaa ttggacaact tcctggtctg tgaaatcttg accttttttg
    44101 agccaccagg tcaatgtctc gataaagttg gacatgacca agtgttggag gtaagaagta
    44161 ggtagacttg ggtgagtttg cttcaaatca gcagccagca tgggatagac gtggtgctca
    44221 agctctctct gtagttgacg gaggaaatag tcatttttgg agaatagtag actggcgata
    44281 tggtcttggt ttttctgaaa atgcagaaag aggtgggcga ggtagtcttc ggttgaaatg
    44341 gcttgctctc tttcaaaaag atgatggaag aggtagcggc agagctgatc cagaagaagc
    44401 tctttactct catagtgaca gtaaaaggtg gatcgtccca catctgcgag atcaatgata
    44461 tcctgaacag tagtggcctc gtagccctta gcattcaaaa gttgtataaa agcttgatag
    44521 atggcttttt tggttttgct gatacggcgg tcaatgttag tcatatggac acttaaggca
    44581 aattgttcag aactgaataa agctgacgtt ttgcttctat cctttctttg agttttagtg
    44641 gataatgata atgaacaaga tgttcataaa tctattataa caaaggaatg agaaatatga
    44701 aggcaaaata tgctgtttgg gtggcttttt tcttaaattt gacttatgcc attgttgagt
    44761 ttattgcagg tggagtattt ggttctagcg ctgttcttgc tgactctgtg catgacttgg
    44821 gagatgcgat tgcaattgga atatcagctt ttctagaaac aatctccaat cgtgaagaag
    44881 acaatcagta caccttgggc tataagcggt ttagcctgct aggagccttg gtaacagctg
    44941 tgattctcgt aacgggctct gttctagtca ttttggaaaa tgtcacgaag attttgcatc
    45001 cgcaaccagt caatgatgag gggattctct ggttaggaat tattgcgatt actatcaatc
    45061 tgttagcgag tctggtggtt ggtaagggaa agacaaagaa tgagtctatt ctgagtctgc
    45121 attttctgga agatacgcta gggtgggtag ctgttatcct gatggcgatt gttcttcgat
    45181 ttacggactg gtatatccta gatcctcttt tgtcccttgt catttctttc tttattcttt
    45241 caaaagccct tccacgtttt tggtctacac tcaagatttt cttggatgct gtgccagaag
    45301 gtcttgatat caagcaagta aagagtggcc tggagcgatt ggacaatgtg gtcagcctta
    45361 atcagcttaa tctctggact atggatgctt tggaaaaaaa tgccattgtc catgtttgtc
    45421 taaaagaaat ggaacatatg gaaacttgta aagagtctat tcgaattttc ctaaaagatt
    45481 gtggttttca aaatattacc attgaaattg atgctgacct agaaactcac caaacccata
    45541 agcgaaaggt gtgtgacttg gaacggagtt atgagcatca acattagaaa aaagtgaaaa
    45601 atacttgggt actatcttat ttggaataga gtaatttctt tattatttaa atatttcaaa
    45661 aattggtaag agaagagcat tgtataaact tcagatatat gattgttaat gataaaaatt
    45721 tttcgattag atacaaaatg cttgacttgg agtcaactca aagttatata ataagataag
    45781 tgagttagaa tagcgtgaat tcagtgaatg aaatgagagg aggttagcgt gtgaatatta
    45841 aatctgccag tgatttgttg ggaatttcag cggatacgat tcggtattat gaacgggttg
    45901 gtcttgtgcc accgattact cgtactgcta ctgggattcg tgattttcaa gatcaggata
    45961 tcgaagcgct ggaatttatt aagtgttttc gttcggcgtg tgtctctgta gatagtttag
    46021 ttgactatat gtcgctctac caaaagggag atgaaacgag agaggagagg cttggtattt
    46081 tagaagagga aaagcaaaaa ttagaggagc gcttgtctca gctacagaca gctttaaatc
    46141 gtttaaatct caaaattaaa ctttataagg aaggaaaatt ttaaatgaaa tcagcagtat
    46201 atacaaaggc aggtcaggtt ggacttgcta gcattgaacg tccgcaaata atagaagcgg
    46261 atgatgtgat tattcgtgtg gttcgtgcgt gcgtttgtgg ttcagattta tggaggtacc
    46321 gtaatccaga aacgaaagct ggacacaaaa atagtggaca cgaagcgatt gggattgttg
    46381 aagaagctgg ggaagccatt acgacggtga aaccaggtga ttttgtgatt gtccctttta
    46441 cacatggatg tggtgagtgt gatgcctgtc ttgctggatt tgacggttct tgcgacaatc
    46501 atattggcaa taatttgggg ggtgattttc aggcagaata tattcgcttc cactatgcaa
    46561 actgggcgct ggttaaaatc cctggtcaac cttctgacta tacagaaggg atgctcaagt
    46621 cccttttgac tcttgcagat gtcatgccga caggctatca tgcggcgcgt gttgcaaatg
    46681 ttcaaaaagg ggacaaggtt gttgttatcg gtgatggggc tgttggtcaa tgtgctgtca
    46741 tcgcggctaa gatgcgtgga gcatcacaaa ttatccttat gagccgtcat gaagaccgtc
    46801 aaaagatggc tatggagtca ggtgcgacag ctgttgttgc agaacgtggt caagaaggaa
    46861 ttaccaaggt gcgtgaaatc ctcggtggag gagcagacgc agcacttgaa tgtgttggta
    46921 cggaggctgc tatagaacag gcgctaggtg ttcttcataa tggagggcgt atgggctttg
    46981 taggagtccc acactataat aatcgtgctc ttggttcgac atttatgcaa aatatctctg
    47041 tagcaggtgg ggcagcttct gctacaacat acgataagca atttttacta aaagccgtcc
    47101 ttgatggtga tatcaatcca ggtcgcgtct ttacttcaag ttataaactg gaagatatcg
    47161 accaagccta caaagatatg gatgaacgta agacaattaa gtctatgatt gtaatcgaat
    47221 aaaaaacgaa taggagtttt agaactctat tcgtttttta tgttatccta ttcttgattt
    47281 agggtacttt ctcttaatgt cagtctggtt cccagcatgg tcaggctagg aattttgcga
    47341 ccgtggagga cttccttgtt aagaatatcc atacctgctc gccccatttc ttcagtataa
    47401 actgtaatac tagagagggg aggatagacc tgtttggtca gactggtgtc gttgaatgaa
    47461 atgaggctga cgcgatctgg caggctgatt ccagcttctt ggagggcacg gagggcaccg
    47521 atagctaaac tatcgctggc tgcgaaaaat gctggcggaa gttggtctcc caagctctga
    47581 atggcctcct tcattaagtc atagccagac tgggcagtaa atcttccttg aaagaccagt
    47641 tcatcatgat agattcccct cgcttgactg tagtttttga agttttctag acgcttgtcc
    47701 tgaatgattt cttcttggtc agttgtttct tcaaggcctg ttagaatccc gatacggtcc
    47761 atcccttgac tgaggaaata atcgacaacc tgtttcatgg cagtgtaaaa gtccgtaata
    47821 atacaggtat gtcccaggga aagtgtatcg ctgtctagaa atacaagagg cttttggtat
    47881 tcttcaaagg cagaaatctg agctcggcta aattttccga tgcagagaat cccaatcact
    47941 tcctcgctta aggtaaaagg atggtcatta aaatagcgca agatatcata gtccaactct
    48001 tgggctcttt tttctattcc taggcgaatc tggtagtagt agaggtcgtc cagctcccct
    48061 tgttcgctga cccattggat aatggcaatc ttttgcttgg gtttgtggga ctcgcctgtc
    48121 ttgaggtgct tggtgtagcc cagctcttca gcaatggtta aaatacggtg tctggtttct
    48181 tctgtaacag ataggctctg gtcgcgattg aggacgcggg atacggtcgc gatagagaca
    48241 gaggctagct gtgcaatgtc ttttaaggta gccataaatc ctccttgatt aggttagtat
    48301 atcatatttt tcttcttttt actgatattt tactaaaatt ttagtaaaaa gtattgacct
    48361 tgggaaattc cttggataca atagaaagaa aacgattaca cgttaagatg gcttaacgga
    48421 cagtcaaagg agaattcata tggcacaaca tcttactact gaagtccttc gcaaagactt
    48481 tcttgctgtt tttggtcaag aagcagacca aaccttcttt tcaccaggcc gtattaattt
    48541 gattggtgaa cacacagact acaacggtgg gcacgttttt ccagctgcta tttccttggg
    48601 aacttatggt gcagctcgca agcgtgacga ccaagtttta cgtttctact cagctaactt
    48661 tgaagacaag ggcataattg aagtgcctct cgctgacctc aagtttgaaa aagagcacaa
    48721 ctggaccaac tatccaaaag gggttcttca tttcttgcaa gaagctgggc acgtgattga
    48781 caaaggtttt gatttttatg tttatgggaa tatcccaaat ggttctggct tgtcttcttc
    48841 agcatccttg gagctcttga caggagtcgt ggcagagcat ctctttgatt taaaactaga
    48901 ccgtctcgat ttggttaaaa tcggaaaaca aacagaaaat aactttatcg gagtcaactc
    48961 tggtatcatg gaccagtttg ctattggtat gggggctgat caacgtgcta tttaccttga
    49021 taccaacacc ttagagtatg atttggtgcc acttgatttg aaggacaatg tcgttgttat
    49081 catgaacacc aacaaacgcc gtgaattggc ggactctaaa tacaatgaac gtcgtgctga
    49141 gtgtgaaaaa gcagtggaag aattgcaagt tgccttggat attcagaccc tgggtgaatt
    49201 ggacgagtgg gccgttgacc aatatagcta tctaattaaa gatgaaaatc gtttgaaacg
    49261 tgctcgccat gctgtgcttg aaaaccaacg tacccttaaa gctcaagcag cccttcaagc
    49321 aggtgatttg gaaacatttg gtcgtttgat gaatgcgtca cacgtttctc tggagcatga
    49381 ttatgaagta actggtttgg aattagatac ccttgttcac acagcttggg cacaagaagg
    49441 agttctcggt gctcgtatga caggggctgg ttttggtggc tgtgccattg ccttggttca
    49501 aaaagatact gttgaggcct ttaaggaagc tgtaggcaaa cactacgagg aagtagttgg
    49561 atacgctcca agcttctata tcgctgaagt tgcaggtggc actcgcgtcc ttgactagtc
    49621 aaaaggaggc tctatagtga ccttagtaga taaatttgta acacatgtca tttctgaaag
    49681 ttcatttgag gaaatggatc gaatctacct gaccaatcgt gttttggcac gagtgggaga
    49741 aggtgttttg gaagttgaga ccaatctgga taaattgatt gacctcaagg accagctagt
    49801 tgaggaagcc gttcgattag agacgattga ggatagtcag actgcgcgtg aaatccttgg
    49861 tactgaactg atggacttgg tgactccttg tccgagtcag gtcaatcgtg acttctggga
    49921 agcctatgcc tactctcctg agcaagcgat agaggatttt tatcaactca gtcagaaaaa
    49981 tgactacatc aaactcaagg ccattgctaa aaatatcgct tatcgtgttc catctgatta
    50041 tggagaactt gaaattacca tcaatctctc taagcctgaa aaggatccga aagagattgc
    50101 ggtagccaag ttggtgcaag ctagtaatta tcctcagtgt caactttgtt tagagaatga
    50161 gggttaccat ggtcgggtca accacccagc tcgcagcaac caccggatta tccgttttga
    50221 aatggttggt caggaatggg ggttccagta ttcgccctat gcttacttta atgagcattg
    50281 tatcttttta gatggccagc atcgtcccat ggccattagt cgtcagagtt ttgaacgtct
    50341 gttggctatc gtagagcagt ttccaggata ttttgctgga tctaatgccg acctgccgat
    50401 tgtggggggc tctattctaa ctcacgatca ttatcaggga ggccgtcacg tatttcctat
    50461 ggaattggct cccttgcaaa agaccttccg atttgctggt tttgagcagg tcaaggctgg
    50521 aattatcaag tggccaatgt ctgtcctacg cttgacttcg gattccaaag aggatttgat
    50581 taacttagct gataagattt tccaggaatg gcgtcagtat tcagattcta gtgtgcagat
    50641 tttagcagag acagacggga caccgcatca caccatcaca ccaatagcgc gtaagcgtga
    50701 tggacagttt gagttggact tggtcttgcg agacaatcag acttcagcag agcatcctga
    50761 tggcatctat catccccaca aggatgtcca acatatcaag aaggaaaata tcggcttgat
    50821 tgaggtcatg ggcttggcaa tcttgccacc acgtctgaaa gaagaagtag agcaagtcgc
    50881 tagctatctt gtaggagaag ctgttacagt tgccgattat catcaggagt gggcagacca
    50941 actcaaatcc caacatccag acctaacgga taaagaaaaa gcccttgcaa tcgtcaagga
    51001 ctctgtgggt gctatctttg cgcatgtact tgaggatgca ggagtctaca agcagacaga
    51061 acaagggcag acagccttta tgcgctttgt ggaacatgtc ggaatttcac tagactagga
    51121 gctttctcct tgcacagtcc tataaaaagt agtatcatag tgtcgtttga aatatcagga
    51181 ggaaacgatg aaagactttc attttgacgc tatatctgcc tttgaaaatt acgaaattga
    51241 aaaaatgaga gatggtcacg ttgtggtgac gaccaaagta gtgaactcgt cgctcaacta
    51301 ctatggcaat gcccatggtg gctatctatt cacgctatgt gaccaaatca gtggtttggt
    51361 ggttatctcg ctgggacttg atggggtgac attccaatcc tctatcaact accttaaggc
    51421 aggaaaactc gacgatgtat tgaccattaa aggagaatgt gtccatcaag gccgtacaac
    51481 ctgtgtgatg gatgtggata tcaccaatca agagggcaga aatgtctgta aagcaacctt
    51541 taccatgttt gtcacaggcc aaaggtctga ggaaagacgg gtaaggatat aaagagtaat
    51601 ttaatagagt gaggtgaatt ttggaattta taagatttgc cttactcatt ttttgatatt
    51661 gatatgattt aattctaaaa tagaaaattt agtaatgtgg tagaaaatac aagagttgtg
    51721 ttttaatttc tatggtataa ttaaaagcat gaagataaaa gaaataaaga aagttacttt
    51781 acaaccgttc acgaaatgga caggtggtaa aagacaatta ttgcctgtta ttagagaatt
    51841 aatgcctaaa acctataaca ggtatttcga accttttgtt ggaggtggag ctttattttt
    51901 tgatttggct cctaaagatg cagttattaa tgattttaac gctgaactaa taaattgcta
    51961 tcaacaaatt aaggacaatc ctcaagaatt gattgaaatt ttgaaagttc atcaggaata
    52021 taattcaaaa gaatattatt tagatttacg ttctgcagat cgtgatgaaa gaatagatat
    52081 gatgtccgaa gtacaaagag ctgcacgtat tctatatatg ttgagagtga actttaatgg
    52141 tctatatcgt gtgaattcta agaaccaatt taatgttcca tatggacgtt ataagaatcc
    52201 taaaattgtt gatgaggaat tgatatctgc tatttcagtt tatctaaata acaatcaact
    52261 agaaattaaa gtgggagatt ttgaaaaggc aattgtagat gttcgaacag gagattttgt
    52321 gtattttgac cctccatata ttccattgtc tgagacgagt gcatttacgt cttatactca
    52381 tgagggattc tcttttgcag atcaagtaag attaagagat gcctttaaga gattgagtga
    52441 tacaggagct tatgttatgt tatcaaattc ttctagtgct ttagtagagg agttgtataa
    52501 ggattttaat atacattatg ttgaagctac ccgaactaat ggagcaaaat cttcaagtcg
    52561 aggaaaaatt tctgaaatta tagtcacaaa ttatgaaaaa taacgaatat aagtatggag
    52621 gtgttcttat gacaaaacca tactacaata aaaataagat gattcttgtt cattcagata
    52681 cgttcaagtt cttatcaaaa atgaaaccag aaagtatgga tatgattttt gctgatccac
    52741 cttatttttt aagtaatggt ggaatatcta attctggggg acaagttgtt tctgttgata
    52801 aaggagattg ggataaaatt tcttcattcg aagaaaaaca tgagtttaat cgtaaatgga
    52861 ttcgcctagc aaaagaagtt ctgaagccta atgggacggt atggatttca ggtagtttgc
    52921 acaacatata ctcagttgga atggcattag aacaagaagg ttttaaaatt ctgaataata
    52981 ttacttggca gaaaacaaac cctgccccca atttatcttg tcgttatttt acccattcta
    53041 ctgaaaccat tttatgggcc agaaaaaatg ataaaaaagc tcgtcattac tacaattatg
    53101 atttaatgaa agaattgaat gatggaaaac aaatgaaaga tgtctggacc ggttctttaa
    53161 caaagaaagt tgaaaaatgg gctgggaaac atccaactca aaaaccagag tatttgttag
    53221 aacgcattat tttagcctct actaaagagg gtgactatat tctagaccca tttgttggta
    53281 gtggcactac gggtgttgtt gcgaagcggt taggtagaag atttataggt atcgatgctg
    53341 aaaaagaata tttaaaaatt gcaaggaaga ggttggaggc agaaaatgaa acaaactaga
    53401 aattttgatg agtggttgtc aacgatgacc gacacagtag ctgactggac ttattataca
    53461 gattttccta aggtttataa aaatgtatct agtataaaag ttgctctaaa tattatgaat
    53521 agtcttattg gtagtaaaaa tatacaagag gattttttag acttatatca aaattatcca
    53581 gaaattttga aagttgtgcc tctacttatt gctaaacgtt tgagagatac gattattgtt
    53641 aaggatccga taaaagattt ctattttgat tttagtaaac gaaactatag tattgaagaa
    53701 tatactatgt ttttggaaaa atcaggtata tttgatttat tgcaaaatca tttagtatca
    53761 aatttagttg actacgttac aggtgttgag gttggtatgg atactaatgg gcgcaaaaat
    53821 cggactggag atgcgatgga aaatattgtt caaagttatc ttgaagctga agggtatatt
    53881 ttaggagaga atttatttaa agagattgaa caaaatgaaa tagaggaaat tttttctgtc
    53941 gatttatctg ctattacgaa tgatgggaat actgtgaaac gttttgattt tgtcataaaa
    54001 aatgaacaag tgctttatct gattgaggtt aatttttatt caggaagtgg ttcaaaatta
    54061 aatgagacgg ctagatctta caaaatgatt gctgaagaaa ttaaagctat tcctaatgtt
    54121 gagtttatgt ggattactga tggacaaggt tggtataagg ctaagaataa tttacgagaa
    54181 acatttgata ttttaccatt cttatataat attaacgatt tggaacataa tattttaaag
    54241 aatttgaaat aggtccaatt caattagatg ggaattggga ttgattgtat ttataatcaa
    54301 tttgtgataa acaaaaaaga ggctcgcacc tctttttctt atttcttttt atgatttaat
    54361 acggcattga ggacaatagc gagtaggctg gctacgacga ttccgtttga gaagaacatt
    54421 tggaaggctg ttggcatgct gacaaagaga ttactgttgt tgagaccgac acctgcagcg
    54481 attgaaacag ctgcgataag gaagttgtgt tcattgttag caaagtcaac tcgggcgagg
    54541 atttgcatcc cttgaataga tacaaaacca aacatcacca gcatggcacc gccgaggacg
    54601 gagcttggaa tgatttgggc aagggcacca aacttaggaa gcagtccaag gagaaccagg
    54661 aaaccagctg cgtagtagat tggcaggcgt tttttgatgc ctgacaattt aaccaaacca
    54721 acgttttgtg aaaatccggt gtaagggaag gtgttaaaga ttcctccgag aagtacggcc
    54781 aaaccttctg cgcggtatcc gttgcgaagg cgcgtgctgt cgattggatc ctttgtgata
    54841 tcagacaagg ctagataaac accagttgac tcaaccatag acaccgttgc gatgatacac
    54901 atcatgacaa tagatgagat ttcaaaggtt ggcatcccaa agtagagtgg aattgggaca
    54961 tggacaagtg gagctaccgc aacaggagag aagtccacca agcccatagt agcagcaatg
    55021 gcagttccaa caaccagacc aatcaaaata gagatagact tgataaatcc tttggtaaag
    55081 atattgatca agaggataat cagaacagta atagctgcaa gcaagagact ttgaccagtt
    55141 ggctctggaa cgttatttcc catatttcca atagcgacag ggatcaaggt taaaccaatc
    55201 gtggtaataa cagatcctgt tacgatagat gggaagagat tggctacttt tgagaagatg
    55261 cctgaaacaa gaaccacgta aatcccagat gcgataaggg caccaaacat agcgccacta
    55321 ccatggcttt gcccaatcat aatcaaggga gcgaccgact ggaatgcaac tccaagaacg
    55381 actgggagtc caatcccaaa gtatttgttg agttggagtt ggaggaaggt tgccacccca
    55441 cacatgaaga tatctgtaga aatcaggtag gtcaactgct cagctgaata gccaagggct
    55501 gtcgcaatca tgatgggaac caggatagat cctgagtaca tggctagtaa gtgctgcaag
    55561 cccagaacgg ctgcttgcga gtgtttttct tgagtttgca ttagagatct gcctccttaa
    55621 atacgacctg accattttca aaacgatcca aacgagcaag tgataggaca gggtagcctg
    55681 ctttttcaag caaatcacga ccatcttgga aggatttctc aatcacgata ccgatagctt
    55741 ggactgtggc accggcctgt tcgatgattt gaatcaagcc tttagcagct tggccattag
    55801 caaggaaatc gtcgataatc aaaaccttgt cctctggtga gaggaatttt ccagcgatag
    55861 aaacagtgct ggtcacctgc ttggtaaagg agtagacttg agcagttaag atgccttcgt
    55921 tcatggtgat gttcttagct tttttggcga aaatcatggg aacgtttaag gcttcagctg
    55981 taaaaacggc tggggcaata cccgacgctt caatggttac gaccttggta atgccagcag
    56041 cagcaaattt ttccgcaaaa accttaccaa tctctcgcat caagctaaag tcaacttggt
    56101 gggttaaaaa ggaatctacc ttgaggatgt tatcacccaa gatatgccca tccttgagga
    56161 tgcgctcttc taataatttc ataagacctc ctaaagtcta aaagttaatt tacttgttgt
    56221 ttaaatgttt ctatagtgat cccttttgct aatattatat atttgataaa actattacga
    56281 gcgaagcgag tcttatcaaa tatttcccgt tgtagtggta tcatagacaa taatcttgtt
    56341 attgtctatg acgggatttt tgagagtaaa atagttcggg gaactatttt agcctaagcc
    56401 tagaaatgaa agagctaggg gctcaaaaat tagggatgaa attccctgga ttcctgaaat
    56461 tattcacagg ataatttcac ctcccgtccg cactaattaa gggaaatatt aaaaatattc
    56521 aaaaaagacc tacttaatct ctaagtaagt cccccaaata ggcatggcaa aaacggccat
    56581 atctcactgc tgacttactt attgttaggt gttccggcac cttgtagaaa cgtcgtgcca
    56641 attcacgaca taaacaagta aaacgatatt caattttaaa taggcttgag ccaatgtttt
    56701 tattttacac taaataactt taaaaatcaa ctattttgtt agtgtttcgg tttaaaaaac
    56761 gaacaaacag aagagagggt gaataaaaac tccattgtaa gctaacattt atactaaatg
    56821 aaaatcaaag agcaaactag gaagctatcc acaacctcaa aacactgttt tgaggttgtg
    56881 gatagaattg acagagtcag tatcatatac ctacggtaag gcgacgttga cgtggcttga
    56941 agagattttc gaagagtatt agaagatttt tccatcataa aaggcatact atcaagtttt
    57001 tagacacctg acaatatgcc tttttctaac tttaaagact tttcccaatt tttattattc
    57061 tactcgctaa atcttaaaaa atagccatct ggatccaaaa ctgcaaattt atgaggatag
    57121 atatagggat cactgacacg aaactttctt ttggtcaagg gacgataaat aggatagttt
    57181 gcctccatca ctttttgata gagttttgga acatccttta tgccaaagga gagattgact
    57241 ccacgaccaa aggggtaggt cagttcagct agttgatcct ttgttccctc ctctaacatt
    57301 agttgacact cttcaagaga aagagaaagt tttcttctgg acgttggtat tcaatcctaa
    57361 aacccagtaa accacagtag aaggaccggg actgttcgat attcgataca agaaactcgg
    57421 gaatgaccgc attgtagtcc atatagaaaa tccttacaag tcaatttcca agacaatcgg
    57481 tgtatggtct tggcgagcac ctgagtcaat catatcagat ttagtgacct tgtcagcgat
    57541 acggttactt gtgagccagt agtcgattct ccagcctgta ttgttgattt tagaagtttt
    57601 gctgcgttgt gcccaccaag tgtagcgttc aggaacatcg ccatgaacat ggcggaaggt
    57661 atcagtaaat ccagttgcca ataggttggt aaatccagca cgttcctcgt cagtaaatcc
    57721 aggtgaacgg cggttgctag caggatttgc aaggtcgatt tcattgtggg ctacgttgta
    57781 gtcaccggtc gcaaggactg gtttttcttt gtctagttca gccaaatact ccgcatattt
    57841 gacatcccag acttggcgtt cttccaagcg tttaagacca tcgccagcat ttggtgtgta
    57901 aacttgggtc acgaaaaatg catcaaattc tagagtgatg atgcggcctt ccaagtccat
    57961 ggtagaaggg gcaccgattt ctgggaaagt gatagtaggt gtaagttctt tcttataaag
    58021 gaacatggtt ccagcatagc ctttacgggc aggctcttgg gaagagcgcc acgtgttttc
    58081 gtagcctggg aagagttctt ctaaaatttc cacgtgtttc tttgtaggtc ctttggcaga
    58141 aagcttggtt tcttggatag caatgatatc agcattttca gcgaccaagg tttgtaggac
    58201 ttcttgggac aatttggcac gagctgagtc actagttagg gcagcgttta gggaatcaat
    58261 attccatgag ataagtttca taaagttacc tttttcattc agattataga ttttattata
    58321 ccaaaaaaag atctatttcc ccaacgtatg gtttgaaaaa ttactctctt tcgtttataa
    58381 ttaagaatga ttttatgaaa gggagtgaaa atacatgaaa ttctactctt atgactatgt
    58441 actcagccaa atcggtcagc aaaatggtat catggttggc tttgggattg ttctattagc
    58501 tgtgacagtt tttttgcttt taaggcatac catgataaaa agggaaccga atttcgtgag
    58561 ttggtcatga tttcagctct agccttattt agctctgctt ttggtcagca tcacgactta
    58621 tcaaaacaat caagtttcta acaataaatt tcaaacttca cttcatttca tcgaggttgt
    58681 ttccaaagat ttgggagtag acaagtcaga agtctatgtt aatacttcca caaacacaga
    58741 tggcgcactt atcaaggtgg gagatcgcta ttatcgtgcc ctaaacggaa gtgagccaga
    58801 caagtacctg ttagagaaag tcgaattgta taagacagac gcaattgaac tggtggatgt
    58861 gaacaaatga cacttaatta tatcgaaatt ttaatcaaac tggtcttgac tctcaaatag
    58921 ttcaacaaca atgttcactt tatgaaacgt ttgattgatg gtaagccaac tctccttatc
    58981 aaaaatggga atattgaccc ataagcctgt cgttcagttg gtttgtctgc atcggatgta
    59041 gccctcaaac ttcgtagcca agggattttc cagatgaagc aagtcaaacg agctgtgcaa
    59101 gagcaaaatg ggcaactcat cgttgtgcaa atgggagatg aaaatcctaa gtatccagtt
    59161 gtgactgacg gtgtgattca agtagatgtc ttggaatcga ttggtcgtag cgaagagtgg
    59221 ttgcttgata acctcagcaa acaagggcat gacaatgtag ccaatatctt tattgctgaa
    59281 tatgacaagg gtgctgttac agtcgtaact tatgaataag aaaaacctgg ggtcttgtac
    59341 tcttcgaaaa tctcttcaaa ccgcgtcaac gtcgccttgc cgtatgtagg ttactgactt
    59401 cgtcagttct atctacaacc tcaaagcagt gctttgagca gcctgcggct agtttcctag
    59461 tttgctcttt gattttcatt gagtattggc ctcaggcttc catttgcaat cagaaaggga
    59521 ttttatgtcc attattcaaa aactttggtg gtttttcaag ttagaaaaac gccgttatct
    59581 agtcgggatt gtggccctgg tcttggtttc cgtcctcaat ctcattcctc ctatggttat
    59641 ggggcgggtc attgatgcca tcacatcggg gcaattaacc cagcaggacc tccttcttag
    59701 cctattttac ttgctacttg cagcctttgg tatgtactat ttgcgctatg tgtggcgtat
    59761 gtatatcctt gggacctctt attgcttggg acagatcatg cggtctcgct tgtttaagca
    59821 tttcacaaaa atgtcgtcag ccttttatca aacctatcgg acgggtgatc tgatggcaca
    59881 cgcaaccaat gatatcaatg ccttgactcg tttagcaggt ggcggtgtca tgtctgcggt
    59941 ggatgcctct atcacggctc tggtgacttt gttgaccatg ctctttagca tctcatggca
    60001 gatgactctt gttgccattc tccccctacc tttcatggcc tatgcgacta gtcgcctagg
    60061 gagaaagact cataaggcct ttggcgaatc ccaaactgct ttttctgaac tcaataacaa
    60121 ggtacaggag tccgtatcag gtatcaaagt gaccaagtct ttcggttatc aggcagacga
    60181 gttgaagtct tttcaggcag tcaatgaatt aaccttccaa aagaacctgc aaaccatgaa
    60241 atatgatagt ctctttgccc ctatggttct cttgtttgtt ggttcgtcct atgttttaac
    60301 gcttttggtt ggctccttga tggttcagga agggcagatt acagttggga atctagtcac
    60361 ctttatcagc tatttggata tgctggtctg gcctcttctg gccatcggtt tcctctttaa
    60421 tactactcag cgagggaagg tttcttacca gcggattgaa aatcttttgt ctcaggaatc
    60481 tcctgtacaa gaccctgagt ttcctctgga tggtattgaa aatgggcgtt tggagtatgc
    60541 cattgacagc tttgcttttg aaaatgagga aacactgacg gatattcact ttagtttggc
    60601 aaaagggcaa accctgggct tggttgggca gacaggctct gggaaaacgt ccttaatcaa
    60661 gctcctcttg cgtgaatacg atgtggataa gggtgccatt tatctaaacg gtcacgatat
    60721 tcgggactat cgtctgacag accttcgcag tctcatgggc tatgttcctc aggaccagtt
    60781 tctctttgcg acttcaatcc tagacaatat ccgctttggc aatcctaact tgcccctttc
    60841 agcggtcgag gaagctacta agctagcccg agtttaccaa gatattgtag acatgcctca
    60901 aggatttgat acgctgattg gtgaaaaagg agtcagtctt tctggtggtc aaaagcaacg
    60961 gttggctatg agtcgggcta tgattttaga ccctgatatc ttgattttgg atgattcctt
    61021 atccgccgta gatgccaaga cagagtatgc gattatcgac aacctcaagg agacgcgaaa
    61081 ggacaagaca accattatca ctgcccatcg cctgagtgca gttgtccatg cagatttgat
    61141 tttagtcctg caaaatggtc aaattatcga acgaggcagg cacgaagact tgctagcttt
    61201 ggatggctgg tatgcccaaa cctaccagtc tcagcagctg gaaatgaagg gagaagaaga
    61261 tgcagaataa acaagaacaa tggactgtat tgaagcgctt gatgtcctat ctcaagcctt
    61321 atagactcct gacctttttg gcactcagct ttctcctagc gacgacggtc attaaaagtg
    61381 tcatacccct cgtggcttcc cactttatcg accagtatct cagcaatctt aaccaactag
    61441 ccgtgaccgt tttgctggtc tactatggtc tctacatcct acaaactgta gttcagtatg
    61501 tcggcaatct tctctttgca cgcgtgtctt acagtattgt tagggatatt cgtcgggatg
    61561 cctttgccaa tatggagaaa ctgggcatgt cttactttga caagacgcca gcaggttcta
    61621 tcgtttctcg tttgaccaac gataccgaga cgattagtga tatgttttct gggattttat
    61681 ccagctttat ctcagcagtt tttatctttc tgacaaccct ttataccatg ttggtgctgg
    61741 attttcgttt gacagcatta gtcttgctct ttctcccctt gattttcctt ttggtcaatc
    61801 tctatcgaaa aaagtcagtg aaaatcatcg agaaaaccag aagtctcttg tcagatatca
    61861 atagtaagct ggcagagaat atcgagggaa tcaggattat tcaggctttt aatcaagaga
    61921 agcgcctgca ggcagaattt gatgaaatca accaagagca cttggcctat gccaaccgtt
    61981 ctgtagcctt ggatgccctc tttttgagac ctgccatgag tttgttgaaa cttctaggtt
    62041 atgctgtctt gatgacctat tttggctacc gtggtctttc tatcgggata acggccggga
    62101 ccatgtatgc ttttatccag tacatcaacc gcctctttga ccctttgatt gaggtgacgc
    62161 aaaacttttc aacactgcaa acgtctatgg tttctgcagg ccgtgtcttt gccttaatcg
    62221 atgagaggac ctatgagccc cttcaagaaa atgggcaagc caaagtcaaa gaaggcaata
    62281 tccgttttga acatgtgtgt ttctcgtatg acggtaaaca tccgattctg gatgacattt
    62341 ctttctctgt taataagggt gaaaccattg cctttgtagg tcatacaggt tcagggaaat
    62401 cgtctattat caatgtcctc atgcgctttt atgaattcca gtcagggaga gttctcttgg
    62461 atgatgtgga tatcagggat ttcagtcaag aagagctgag aaaaaacatc ggtttggttt
    62521 tacaggaacc cttcctctat catggaacta ttaagtccaa tatcgccatg taccaagaaa
    62581 tcagtgatga gcaggttcag gctgcggcag cctttgtgga tgcagattcc tttattcaag
    62641 aacttcctca ggggtacgac tcccctgttt ccgagcgtgg ttcgagcttc tctactgggc
    62701 agcgccagct tcttgccttt gctagaacag tcgccagcca gcctaaaatc ctgattttgg
    62761 atgaagcgac agccaatatt gactctgaaa cagaaagttt ggttcaagct tctctggcga
    62821 agatgagaca gggccgaaca actattgcta tcgctcaccg cctttctact attcaagacg
    62881 ccaactgcat ctatgtcttg gataagggac gcattatcga gagtggaacc catgaggacc
    62941 tcttgactct gggaggaacc tatcacaaga tgtatagttt gcaggcaggg gccatggcct
    63001 atactctttg aaaatctctt taaaccatgt cagctttatc tgcaatctca aagctgtact
    63061 ttgattttca ttgagtacta gaaggaaatc cttcaaatta cagatttctt tcaccgcctt
    63121 ttccattttg tggtataatg aaaaatgttg acaaatagta taataaaaac aaaggagaac
    63181 agcatgctga aatgggaaga cttgcctgtg gaaatgaaat caagcgaggt tgagtcttac
    63241 taccagcttg tctctaaaag gaagggttcg ctgattttca agcgttgctt ggactgggtt
    63301 ttggccttgg tcttactggt tctaacttct cccatctttc tcatcttgag catttggatc
    63361 aagttggata gcaaggggcc agtgatttac aagcaagagc gtgtgaccca gtacaaccgt
    63421 cggttcaaga tttggaagtt ccgtaccatg gtgacggatg cggataaaaa aggaagtctg
    63481 gtgacttctg ctaacgatag ccgtattacc aaggttggaa atttcatccg acgtgtccgt
    63541 ttggacgaac tgcctcagtt ggtcaatgtc cttaaaggtg agatgtcctt tgtcggtaca
    63601 cgacctgaag tgccacgtta tacagagcag tatagccctg aaatgatggc aaccttgctc
    63661 ttgcaagcag gaattacctc tccagccagc atcaactaca aggatgagga caccatcatc
    63721 agtcaaatga cggagaaagg tctgtcagtt gatcaggcct atgtggagca tgttcttcct
    63781 gaaaagatgc gctataacct cgcctatctc cgagagttta gtttctttgg ggacatcaaa
    63841 atcatgtttc aaaccgtgtt tgaggtacta aaataaagta gtcataagaa aatgagtaca
    63901 gataaaagga gcaaatcaat gccaaattac aatattccat tttcaccgcc tgatatcaca
    63961 gaagcagaaa ttgctgaagt agcggatacc ctgcgttctg gttggatcac aacaggtcct
    64021 aaaacaaaag aactggagcg ccgcttgtct ctttacacac agacacctaa gactgtttgt
    64081 ctcaactctg cgacagccgc tctggagttg attttacgcg ttttggaagt gggacctggt
    64141 gatgaagtca tcgttccagc catgacctat acggcttcat gtagtgtcat tacgcacgtg
    64201 ggagcaaccc ctgtcatggt ggatatccaa gcagatacgt ttgagatgga ctatgacctg
    64261 cttgagcaag ctatcactga gaaaactaag gtgattatcc cagtagagct cgcagggatt
    64321 gtttgcgatt atgaccgttt gttccaagtc gtggagaaaa aacgtgactt ctttaccgct
    64381 tcaagcaagt ggcaaaaggc ctttaaccgt attgtcattg tctctgatag tgcccacgct
    64441 ttgggatcta cttataaagg acaaccttct ggttctatcg ctgactttac ttccttctca
    64501 ttccatgccg ttaagaactt tacaacggca gaaggtggaa gtgcgacttg gaaagccaat
    64561 ccagtgattg atgacgaaga gatgtacaag gaattccaaa tcctttccct tcacgggcaa
    64621 actaaggatg ctcttgccaa gatgcaactg gggtcatggg aatacgatat cgttacacca
    64681 gcctataagt gcaacatgac cgatatcatg gcttcacttg gtttggtaca attggaccgc
    64741 tatccaagtt tgttgcaacg ccgtaaggac attgtggacc gctatgatag tggttttgca
    64801 ggttctcgca tccatccttt ggcacacaag actgaaactg tcgaatcttc acgccacctc
    64861 tacatcaccc gtgtagaagg agcaagccta gaagaacgca acctcatcat ccaagaattg
    64921 gctaaagcag gaattgcaag taatgttcac tacaaaccgc ttcctctctt gacagcctat
    64981 aagaatcttg gatttgatat gacgaactat cctaaggcct atgccttctt tgagaatgaa
    65041 attaccctcc ctcttcatac taaattaagc gatgaagaag tagactatat cattgagact
    65101 ttcaaaacag tttctgaaaa agtgctaact ttatcaaaaa aatgacaaac tacagtcaag
    65161 cgaaagtgat cctgtcctta aaaaatctaa ttgagtgtaa aaactgttgt tttcaattga
    65221 taatagttta cacctgtagt tgaggctcct ttctcctcag agagagaatt tttataggat
    65281 tttcctttct tgtgggagtc ccgtggtttg aaataagatg tgagcaattt ggtgtagcat
    65341 ttagaatcct tactagacat catttagaaa atctagtgtc ttgttctagt tttcaattca
    65401 ccctattttt tgaaagacgt gagtttccat gagtgagatt gtggaaactc gcgtcttttt
    65461 ttgttttcag aatattgttc aaagttttgt gcctgtcttt catgttctag tcattctttt
    65521 gcatgataga atttatagca tattgatatt ataataatac aaatattcta tacgtttagt
    65581 gatgcttgct atacatcatt agatctcccg cgagacaatc tataaaacac ttgtctacga
    65641 ttacctatat gccctattcc agtattttag aagcactgca tctattttta tcgaggttaa
    65701 atctagcttt tatagaaggt ctatttaaga aatatattgt agtgttttag tttcaatccg
    65761 ccatatgagc gatattcagg taaatatccc tagcgaatgc ttgtatgaca agatatttgt
    65821 tctttcattt ataatttaca acatatcaac aaatttaaat atagtaaatg ggatatttta
    65881 tattcaagct aagaaagata gcatcacttt tgaatggaag gctaaagagc aaactaggaa
    65941 gttggccata gatagctcaa aaccctgctt tgaggttgta gatataataa aatgaaataa
    66001 gaataggaca aatcgatcgg gacagtcaaa tcgatttcta acaatgtttt agaagtagag
    66061 gtgtactatt atagtttcag tctactatag aactgaccaa gtcagtaacc tagacttagg
    66121 gcaaggcggc actgacctag tttgaagaga tttccgaaga gtataaattt taatattttc
    66181 ttgtgttatt ccttgacaat tcaatttgga aaatatatga taaagataat gacagcggtg
    66241 tcattctatc tattttaaga aaagtaataa tcaattgtta aaaatagtaa aaaaattgga
    66301 ggttctgatg aaatattttg ttcctaatga ggtattcagt attcgtaaat taaaggtggg
    66361 gacttgctcg gtactattgg caatttcaat tttgggaagc caaggtattt tatcggatga
    66421 agttgttact agttcttcac cgatggctac aaaagagtct tctaatgcaa ttactaatga
    66481 tttagataat tcaccaactg ttaatcagaa tcgttctgct gaaatgattg cctctaattc
    66541 aaccactaat ggtttagata attcgttaag tgttaatagt atcagctcta atggtactat
    66601 tcgttccaat tcacaattag acaacagaac agttgaatct acagtaacat ctactaatga
    66661 aaataagagt tataaggaag atgttataag tgacagaatt atcaaaaaag aatttgaaga
    66721 tactgcttta agtgtaaaag attatggtgc agtaggtgat gggattcatg atgatcgaca
    66781 agcaattcaa gatgcaatag atgctgcagc tcaagggcta ggtggaggaa atgtatattt
    66841 tcctgaagga acttatttag taaaagaaat tgttttttta aaaagtcata cacacttaga
    66901 attgaatgag aaagctacaa ttctaaatgg tataaatatt aagaatcacc cttccattgt
    66961 ttttatgaca ggtttattta cggatgatgg tgcgcaagta gaatggggcc caacagaaga
    67021 tattagttat tctggtggta cgattgatat gaacggtgct ttgaatgaag aaggaactaa
    67081 agcaaaaaat ctaccactta taaattcttc aggtgcattt gctattggga attcaaataa
    67141 cgtaactata aaaaatgtaa cattcaagga tagttatcaa gggcatgcta ttcaaattgc
    67201 aggttcgaaa aatgtattag ttgataattc tcgttttctt gggcaagcct tacccaaaac
    67261 gatgaaggat gggcaaatca taagtaagga gagcattcag attgaaccat taactagaaa
    67321 aggttttcct tatgccttga atgatgatgg gaaaaaatct gaaaatgtga ctattcaaaa
    67381 ttcctatttt ggcaaaagtg ataaatctgg ggaattagta acagcaattg gcacacacta
    67441 tcaaacattg tcgacacaga acccctctaa tattaaaatt ttaaataatc attttgataa
    67501 catgatgtat gcaggtgtac gttttacagg attcactgat gtattaatca aaggaaatcg
    67561 ctttgataag aaagttaaag gagagagtgt acattatcga gaaagcggag cagctttagt
    67621 aaatgcttat agctataaaa acactaaaga cctattagat ttaaataaac aggtggttat
    67681 cgccgaaaat atatttaata ttgccgatcc taaaacaaaa gcgatacgag ttgcaaaaga
    67741 tagtgcagaa tatttaggaa aagtatcaga tattactgta acaaaaaatg taattaataa
    67801 taattctaag gaaacagaac aaccaaatat tgaattatta cgagttagtg ataatttagt
    67861 agtgtcagag aatagtatat tcggtggtaa agaaggaatt gttattgagg attcaaaggg
    67921 taaaataacc gttttaaata accaatttta taatttatcc ggtaagtata tatcattcat
    67981 caaatctaat gcaaatggga aagaacctgt tatacgtgat agcgatggta atttcaatat
    68041 tgtaacggag aatgggcttt acaaaattgt aacaaataat ttaagtgata aaaacaaaga
    68101 ggaaaaacaa tctaattcaa ataatgtaat tgatagtaac cagaagaacg gagagtttaa
    68161 ctcaagtaaa gataatagac aaatgaatga caagatcgac aataaacaag ataataagac
    68221 agaagaagta aactataaaa tagttggaga tggcagagaa actgaaaatc atattaataa
    68281 atctaaagaa atagtagatg taaaacaaaa attaccaaag actggttcga acaagattat
    68341 ggaactattc ttaacagtga caggaattgg tttacttttg acactaaaag ggttgaagta
    68401 ttatggtaaa gataaataaa atttgttcga tacaaggaag ttccgtagaa aatgaggata
    68461 ttgtaggttc acaaaatcag tatttttgga ttattggtgg agctacagat ttatataatt
    68521 ctaaagagga gataggttat tcagtctcag aagttgtaca tattttatca gaaagtttgt
    68581 cggttaattg taaagaatca aaaactctta aacaaatatt tgaaactgct ttactcgagg
    68641 ttaaagatga aatcggttta aactcatatg aattaacaga gtataataaa atgaaataat
    68701 aataggacaa atcaatcagg acagtcaaat cgatttctaa caatgtttta gaagtagagg
    68761 tgtactattc tagtttcaat atactatatt atcgcttacc aacatttgct tttatatttg
    68821 ctaaactttc agaaaaaaag ttggagtata tgatgctagg tgactgcgtc atgttagtaa
    68881 acgaaatgga aataacggat catagagtag ataacttatt tgaaaaaggg aaaaatgaga
    68941 taaaagattc aattggtaca aatagtgttt taaataaaaa aattatttta caaaaaatca
    69001 gaaaattatc taatcaaccg agtgggtact ggataggttc gttggatgag agatttttag
    69061 accatgctat tattaatcaa atagatgtta ctagtgaaca aattgtttta atgagcgatg
    69121 gcttttatga attctatcaa aataatcaaa ataaaacttt tgaagagtta attaagatga
    69181 gatttaattc ttctgctatt gatccaatct atggaaagaa ggatgatgca agtattctag
    69241 tcattgatgt ttgatatatt gtttaaaata ttaattgtta ctattgaact ttgttaagaa
    69301 gaggtaccta aatgctaagg ttatatttag aaaatgaaat tatagaatta tcaaataatt
    69361 tagagaccat ttgggtatct gtgcttgata aatatgagaa gttatttgaa tatttatcaa
    69421 atgaagaacg aatagaattg attaaagaag atttaatcat aaatgagtca gttctaaata
    69481 ttgataaaaa aggatatgag ttaatttgtt tacaatatcc tgtttcatat gacttaagaa
    69541 gaattattag tgtaataaaa atatcaactg acattgaacg tattggggat agaattgttg
    69601 aaattttaaa aaatctacag attcttcaaa ataatgaaat tttgaagaaa attatttcag
    69661 aaataaaaat acttcatgaa gttatcggac tgcatatgaa tagggctata tcttgttata
    69721 gagaggaaca atctggatgt ttagatatgg ttgttataca aaaacagaat gagatagaag
    69781 agcttagtat aaatatggaa aagaaaataa tgaattacat atttgaagat gatgggaacg
    69841 tttctgaagt aattagtgct ttagatatta ttcatcacct tgataaaatt gctcatacta
    69901 cgcaagcaat ttataaatgg ataatgtata gaaaatatgg gaacataaat tagaaagaaa
    69961 aatatatgaa aacaattatt gataattttg ttgatagagt aattgaatac ggaatgtata
    70021 atgaaattga caaaatatat gtgaaaaata gagtactagc gttaataggt gaggagggaa
    70081 ttgatcgcat ttccgatgaa aatgacctga aacaaataaa agattactta gtggaaatcg
    70141 ccttaaaaaa cggtaaaatt aaagatttaa tcgaggaaaa ggaatgttta ggagcagagt
    70201 taatgaattt catagttcct ttacctagtc gattaaatga tattttttgg agttcatatg
    70261 atatatcacc tcaagaagca gttgaagagt tttataagtt aagtaaagat agtgattata
    70321 ttaaaacttc tgctattgct aagaatattg agtttcgagc atcaactaaa tacggagagc
    70381 tagagattac gataaatttg tcaaaacccg aaaaagatcc aaaaacaatt gctgctgaaa
    70441 aattagtaaa agcaactaat tatcccaaat gtttactatg tatggaaaat gaaggatatc
    70501 aggggcgaat aaattatcca gcacgttcga atcatagaat tattcggttg aaacttggtg
    70561 acgaagtatg gggattccag tattctccct actcatactt taatgagcat gcgatatttt
    70621 tgaatagtca acatgtacca atggctatta cctctaaaac atttgaacaa ttattggaga
    70681 ttgttgatat tttgccagga tattttgctg gttcaaattc tgatcttcct atctcaggag
    70741 gctccattct tagtcataac cactaccagg gagggaaaca tattttccca atggaaaaag
    70801 caaaatttga gagtgaattt tgttttaaag actttgagga tgttaatgct ggtattgtaa
    70861 aatggccaat gtcagtaatt aggttacaaa gtgaaaataa aaatcgcttg ttagatttag
    70921 ctactaaaat tctaaataag tggagagaat attcagattt agaagtagac atcattgcta
    70981 tgactgaaga tgtcccacac catacggtga ctcctattgc tcgtaaagtg gacgggagat
    71041 atgaattaga tattgttcta agagataatc atactactga acagtaccca gatggtgttt
    71101 tccatcctca tcaagatgta caacatatta aaaaggaaaa tatcgggtta atcgaagtga
    71161 tgggacttgc gatattacca cctcgtttga aaccagagtt agaagaagtg ggaaaatatc
    71221 ttttaggaga ggaaaacgca attgcggatt atcatttaga atgggccgac caattgaaag
    71281 aaaaatatcc tcgcattaat aaagaagagg ttaataacgt agttcaacac gaagcaggac
    71341 aagtgtttgc gagagttctg gaagatgcag gagtttataa gaatacaccg tctgggcatg
    71401 aagcgtttat gagatttgtt aagtcggttg gaattaatta ggaggaaacc caaatggcaa
    71461 tattggtaac aggcggagct ggttatattg gtagccatac cgtagtagaa ttactaaatt
    71521 taggaaagga agtcatcatt gtcgacaacc tttcgaactc tagcatcttg gtgctagacc
    71581 gtattgaagc aattacagga atacgtcccg tgttttacga attagatgtt tgtgataaac
    71641 aagcattgag aaaggtattt gaacaagaat cgattgatgc tgcaattcat tttgcaggtt
    71701 ataaagctgt cggagaatcc gtgcaaaagc ctgtgatgta ctacaaaaat aatattatga
    71761 gtacattggc acttgttgaa gtgatgtcag aatttaatgt taaaaagatt gtcttttctt
    71821 caagtgcgac tgtatatgga attaacaatc agtcacctct aattgagacg atgcaaacaa
    71881 gtgcgacaaa tccttatggg tatacgaaag tgatgcttga gcaaatttta aaagatgttc
    71941 atgtggcaga ttcagaatgg agtattgcgt tgcttcgtta tttcaatcca attggtgctc
    72001 atgagtctgg tttgattggg gaagatccct caggaattcc taacaacttg atgccttata
    72061 ttgcacaagt agcggtaggt aagctatcag agctaagtgt gttcggaaat gattatgata
    72121 cgcttgatgg tactggtgtg cgtgattata tccatgtagt agatttagca ataggacata
    72181 taaaagcttt agaaaaagta tctgaaaaaa cagatgttta tatctataac ctaggctcgg
    72241 gagaaggcac tagtgtatta caacttgtaa atacatttga aagtgttaat aagatcccta
    72301 ttccttataa aatagttcca agacgttcag gagacgttgc aacttgttat gcaaatgcag
    72361 acaaagcata taaggaatta aattggagga caacaaaatc gattgaagac atgtgtagag
    72421 atacatggaa ttggcaatca aaaaatccca atggctataa ttgatgatac tgtctatatg
    72481 agtgctgtat tttgaaaaaa ttacttaacc ttttaatgaa atgcatattt aatgaaagat
    72541 aaatttaaaa aaatgtttgc aagtgcttga caaaggaaac ggtttcattg tataatgtaa
    72601 acatgatgac accgatgtca aatataaaaa agaaggtctt tatatgaaaa acttaacaaa
    72661 aattaagttc aaagagaatg gggaatttaa tcatttccct gggaatacag ttgtagcaaa
    72721 tctttatact aaacaagatt tgatggaagt tgttgatatt attcaatcac gttatagaga
    72781 attaccattt atcgataagt ttactttaac tccaaggaat tctattcaca tgactgtaat
    72841 tgaattgttg tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc ttcctctaga
    72901 tacaccttta caggaaatac atgattactt tgctaaacaa cttgaaattt ttccattgtt
    72961 ggatgaagaa attcatatgc gtataactga aatgggaaaa caaaacatac tagttgaacc
    73021 tgcagatgaa gcttctgcaa agagattaga agaaattcgt acttatgtct cagaaaaagc
    73081 aggtgtttgt ttccctaatc atgatagata tcaattccat atttcaattg ggtatcttcg
    73141 gattcctcta accgaagagg aggaagaaga gtttactaaa gtcagagcag aattaactga
    73201 aattttatta gagaagattc caactattac tgtaaaccgt attgactata ctgtatttga
    73261 agatatgaga caatttgttc catatcacga aaaatttaaa taaaataata aaaaaggaga
    73321 acttatcatg aaaaaaatga aagtttggtc tactgtactt gcaacgggag ttgctcttac
    73381 tacacttgct gcttgctctg gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa
    73441 agctgataaa agtcaagaat tagttatcta ttcgaactca gtctcaaatg gtcgtggtga
    73501 ttggttaact gctaaagcaa aagaagctgg ttttaatata aaaatggttg atatcgctgg
    73561 cgctcaatta gcagaccgtg ttattgctga gaagaataat gcagttgcag atatggtatt
    73621 tggaattggt gctgttgatt caaataaaat tagagatcaa aaattactag tacagtacaa
    73681 gcctaaatgg ttagataaaa ttgatcaatc tttatcagat aaagataatt attataatcc
    73741 tgtgattgtt caaccattag ttttaattgg ggcgcctgat gtaaaagaaa tgcctaaaga
    73801 ttggactgaa ttaggtagta agtataaagg taaatattca atttatggtc ttcaaggtgg
    73861 tacaggacgg gcaattctag caagtatctt agttcgttac cttgatgaaa aaggagattt
    73921 aggcgtatca gaaaaaggat gggaagttgc aaaagaatac tttgcaaatg cctatactct
    73981 tcaaaaaggt gaaagctcag ttgttaaagc gttagataaa gaaagcccaa ttcaatacgg
    74041 tatgatctgg ggttctggag cgttaattgg acaaaaagaa caaaatgttg aattcaaagt
    74101 tatgactcct gagattggtg taccatttgt aactgaacaa actatggttt taagcactag
    74161 taaaaaacaa gcgttagcta aagaatttat tgattggttt ggtcaatcag aaattcaagt
    74221 agaatatagt aaaaaatttg gatctattcc tgccaataaa gatgccctaa aagagttacc
    74281 tgaagatacg aaaaaatttg ttgatcaagt gaaaccacaa aatattgact gggaagctgt
    74341 tggaaagcat ttggatgaat gggtagaaaa agctgaatta gaatacgtaa aataagaaat
    74401 aagagttatt ttttatgtcc aagtctctct attatttcta aatttaagga agaaataaag
    74461 agaggctttt ggttttagta atagagggag ttagtgagat gattaaattt gataatattc
    74521 aaattaaata tggtgatttt gttgcaattg ataatctgaa tttagatata catgaagggg
    74581 aattctttac atttcttggg ccttcaggat gtggtaaatc aactactttg agagcattgg
    74641 taggtttttt agatccatca tcaggaagta ttgaagttaa tggaacagat gtcactcatt
    74701 tggaacctga aaagcgtgga attggtattg tatttcaatc ttatgcgcta tttccaacta
    74761 tgactgtttt tgataatatt gcatttggtt taaaagttaa gaaggtagct ccagatgtta
    74821 ttaaagctaa agtatcagca gtggcagcaa aaattaagat ctctgatcaa cagttacagc
    74881 gtaatgtatc agaattatct gggggtcaac aacaaagggt agcattggct cgtgctctgg
    74941 ttcttgaacc taaaattctt tgtctagatg aaccattgtc aaaccttgac gcaaaattac
    75001 gtgtagattt gagaaaagag ttgaaaagac ttcaaaaaga gttaggtatt actactttat
    75061 atgttactca tgatcaagag gaagccttga ctttatctga tagaattgca gtctttaaca
    75121 atggatacat cgaacaggtc ggtacaccag tagagattta tcataattct caaactgaat
    75181 ttgtatgtga tttcattgga gatattaatg ttttgaccga tgaaacagtc cacgaagtat
    75241 tattgaaaaa tacaagcgtt ttcttagagg ataaaaaagg atacattcga ttagagaaag
    75301 ttcgattcaa tcgtgaaact gaacaagatt ttattctaaa agggacaatt attgatgttg
    75361 agttttctgg agttacaatt cactatacaa taaaagtttc tgaaagtcag attcttaatg
    75421 taacaagtat tgatagtcag gctgctatta gatctgtcgg agaaagtgtg gaattattta
    75481 tcacaccatc agacgttctg caattttaag gaggtgcagt atgcgtcata aattaaattt
    75541 aaaagattgg cttattcgtt tagggttaat ctggttctta gtaacattta ttatttatcc
    75601 aaactttgat ctagtagtga atgtatttgt aaaaggagga gaattttccc ttgatgctgt
    75661 acatcgtgtt ctaaaatctc agagggcact tcagagtatt atgaacagtt ttaagttagc
    75721 attttcactc attattacag ttaatgtcgt aggtattctt tgtgttctat ttacagagta
    75781 ctttgatatt aaaggtgcta aaattttaaa attaggttat atgacctctt taatttatgg
    75841 aggagtggtt ttagcgactg gatataaatt tgtctatggt ccttatggat tgattacaaa
    75901 atttttacaa aatgttatcc cttctttaga ctctaactgg tttattgggt atggtgcagt
    75961 cttattcatt atgacatttt caggaactgc taatcataca ttgtttttaa caaatacaat
    76021 tcgaagcgtt gactatcaca ctattgaggc tgctcgaaat atgggagcaa aaccatttac
    76081 tgttttccga aaagtagtgt taccaacctt aattccaact ctatttgcac ttactattat
    76141 ggtttttctt agtggtttat ctgcagtagc agcacccatg attgttggtg gtaaagaatt
    76201 tcaaactata aatccaatga ttattacatt tgcagggatg gggaattctc gtgatttagc
    76261 tgccttactt gcaattattt taggtattgc aactacaatt ttgcttacta tcatgaataa
    76321 gatagaaaaa ggtggaaatt atatttctat ctctaagact aaagcgcctc ttaaaaaaca
    76381 aaaaattgcg tctaagcctt ggaatatcat tgctcacatt gtagcatatg gattgttcac
    76441 agttttcatg cttccactaa tttttatagt attatactca tttacagatc cagttgcaat
    76501 tcaaacaggt aacttaacat tatcaaactt tactttagaa aattatcgct tattctttag
    76561 taatagtgcg gcattctctc cattcttggt cagctttatt tattctatta ttgctgcgac
    76621 aacagcaaca attctcgcag ttgtatttgc tcgtgttgtc agaaaacata aatctcgttt
    76681 tgatttctta tttgaatatg gtgctctact tccttggtta ctaccaagta cacttttagc
    76741 agtaagttta ttatttactt ttaatcagcc acaatttctt gtcttgaatc agattttggt
    76801 aggtagtttg gtaattctac ttattgcata tatagttgta aaaatcccat tttcttatag
    76861 aatggtacgt gctattttat ttagtgttga tgatgagatg gaagatgcag caagaagtat
    76921 gggtgcttca cctttttata ctatgatgaa ggttatcatt ccatttattt taccggttgt
    76981 tctctctgtt attgctttaa actttaactc tttattaact gacttcgact tatctgtatt
    77041 cctttaccat cccctagctc aaccattagg tattacgatt cgatctgcag gtgatgaaac
    77101 agcaacatct aatgcacaag ctctggtatt tgtttataca attgttctga tgattatttc
    77161 tggaacggta ttatacttca cacaaagacc ggggcgtaaa gtaaggaaat aatcatgaca
    77221 gccactagtc ttgggttatc aaatattgaa atagttgtca ggattgtttt atcagtagtc
    77281 attggtagta taattggttt agagagaggg agcaaatccc agcctgcagg catccgaact
    77341 tatagtattg tttgtctagc tgcatgtttg attatgatga cgaatgaata cgtatcttat
    77401 aaatttggga caggagatcc tacacgatta ggagctcaag ttatatcagg tgtgggtttt
    77461 ctaggcgctg gaacgattct tattacagat aaaaagaaaa ttacaggtct gacaactgca
    77521 gcaggcattt gggcttcggc aggaattgga ttagctattg gagtaggttt ttatgaggga
    77581 gctcttttag tagccatttc tgtttggggt gtgatatcca tgttccaacc actaaaaaaa
    77641 tatctgcaaa atcgttctaa aatgattgaa ttgtatatag tggttaaatc tacagaagcc
    77701 tataatcgtg tattggttta ttgtgcagaa aatggtatca gaatgaccga ttcaagaaca
    77761 gcgtttggag atgttaattc tgacagaatt gaatactttg atgttccgga caaaaaaata
    77821 gcgtcattta ttactctgga attatcaggt agatttgaac atcttcgact gatggaagaa
    77881 attgctaata ttgtaggtgt tatttatgtc gaagaaatta gctgaaattt agtaaacaaa
    77941 gggacagatg tttttgtcct tttgcttttt agatgtttta atcatctaat ttttgagtag
    78001 atttttgctc agaggttttt atgaaagatt ataaaatcaa ttttgattta ggtaaaatag
    78061 aatattttga taataattgt ttgatacaag tatacaaatt tatttctttt tatgatattt
    78121 gtgaaatggt gtttgccttt catttacctc ctgatgagtt gataacaaat gttatcttta
    78181 aagaaaaaat taactctatg ttaaaatgtt acattgacag gctattatat gtttttataa
    78241 atcctacaca ttttactgaa aaagttaatc tacaatttta tggcagtttt ttctcatatg
    78301 aatttatttg tcgtgaagtt ggaaacattc ttaaaaataa aggtgtgaaa tgcaatttaa
    78361 acttttttga aggggaagaa tatttgtaaa attaattttg tgaatttgtg gatcttaaat
    78421 aatttactaa attctcttgt taaaaaaaat taaatattgt atagtaatat tagaatgttt
    78481 gtaatagagg actgaaatga aaaatataaa tgggaaaaag gtaactattt atgatattgc
    78541 acgtttatca ggtttttctc caaaaacagt ttcacgagtt attaatggtg gagtaaatgt
    78601 taaagaagaa acttatcaag cgattcaaaa agttatagag gaattgtcgt atattccaaa
    78661 tgcgtatgca aaaaatttaa ctaaaaaaga agctataaat atattgattt ctgtaaaaaa
    78721 aatcgactct tttcctttaa tttggtttca tacgctgtta gataaagtgt tacggacgtg
    78781 taaagaattt ggtgttaatg ctatagttga gtactttgga gaggaggata caattagtaa
    78841 ttcaattata tcaagcacag gtagcctagt agatggtgtt attgtttttt atgaaagtgt
    78901 agatgatatc agaattcagt atttaaagaa gaaccatatg ccttttcttg ttttcggtga
    78961 atctcaaacg tctggagtag tctatgtatc taataataat tttcaagcta cttatgatat
    79021 gatgaaagct gtaactgaag aaaaatttaa aaatatgtgg ttgcttatgg gaggagaatc
    79081 tcatgttaat aaggatcgtg aaagaggtgt gcgttctttt ctgaatgata aaaattactt
    79141 tatggattta aaagtcattt atggcttatc tacaattgat tcagtttatt cttatgcaat
    79201 gcagcacttg actacccaaa attatccgga cattattttt gtttcaggag atgaaaaggt
    79261 tcagggcttg attcgtgcgt gctatgagaa aggaattctt attccagatg atatttctat
    79321 tattggattt gataatattc ctatttctca gtattatact ccagctttgt ctacaattgc
    79381 tcccaattat gttaaattgg ctaaagaaat gatagaaggt gttttagcaa ttattaaagg
    79441 ggaaagtgtc acatctgttg aagtttctcc taaatttgtt aggagacaga gtttctagta
    79501 ttgtttaatt cttgaaaatc ctagtggaaa agatggagtg ttctaaaata agttctgttt
    79561 agcctccatt cagtttctat tgagttggat ccaatttcta acaagtggga catgttcatg
    79621 ttcgatctaa ggaagacatg gtcatattcg aatgatattt tcaaaaaaat cgtaaaaaag
    79681 tcttgacaaa gaaaaaacaa agtattaaaa taagttcaac aaatcagaaa agtaactatt
    79741 tttgatcttc agggagcctg tggtgattgt gaataggtgg ttggaagtag tgaaagtggg
    79801 ctgattttga aaatgaattt gaaacaatga aaattcggtg cgcacacctt acagtgcagc
    79861 ttgttgttaa acaaggcaga gatgtaaagg gatagtccct ttataattga ggtggcaccg
    79921 cgttaccaac gccctcacac ggaagtatat tctgtgtgtg ggcttttttc tatccgtcgt
    79981 ttggtttatc ttttattagg gccttaagtc gctttgatga acttgagttc tatctacagc
    80041 tccatgccta ctactaaaag caaacaaaaa ggctggacta atacgaaaaa agctagtaat
    80101 actcaatgaa aatcaaagag caaactagga aactagccgc aggctgctca aaacactgtt
    80161 ttgaggttgt ggatagaact gacgaagtca gtaaccatac ctacggcaag gcgacgttga
    80221 cgcggtttga agagattttc gaagagtata aaggtgtacc gagatgaaca tctcttcatc
    80281 aatgtctctg gtcgtggagg caaggaccta gctgcgattg cagattacta gaagctaaaa
    80341 aataatagat ggaaaaatta cagttctttc tctcacagag agcttgtggt tgctgaaaac
    80401 aagcagagaa agctgtaaag ttgggttcat ctgaaacgag agaagaaaac atcattctca
    80461 agggagtgcc ctttatcgca cagcctgtta caggagatat ctgagacagg aatgagagat
    80521 aggagaaatc ctataattga ggtggcaccg cgaatttcgt cctcacgcaa gttattttgc
    80581 gtggggattt ttcatacagt caccacggac tagaagtaga actgaaaggg aaattacaat
    80641 ggaacgaatc attcatggag atgtcttatc accaatcttg gcttatatgc gcttaaaggg
    80701 gcaacataag gttattttag agagtattcc gagagacaag gaaacagctc gtttttctat
    80761 cctagcctat aatccagttt ttgagattaa gtttgaaaat ggggttctct atcaaaatgg
    80821 tcaagtgatt gatcgggatc ccttggattt cctttatgaa gtgattcata agagtcagca
    80881 ccactcagag ctaccttttg gtggtggagc cattggtttt gtgggttacg atatgatttc
    80941 gctttatgaa gaaattggtc aaatccctga ggatacaatt gggacgccag acatgcattt
    81001 ctttgtctat gagagctata tggtctttga ccacaagaag gagaagatac atgtcataga
    81061 ggatgcactt tatagtgagc gcagtcaaga ggccttggaa aaatccttga accaagtgct
    81121 tgaggaatta cgcattcctg ctccaaatga atttgaagat ttggatctat ctccgttaga
    81181 cttcaaaccg catatcgctc cacataagtt tgagggaatg gtagaaacag ctcgtgactt
    81241 gattcgtaac ggagatatgt tccaatgtgt actcagccag cgtttttcag cagaagttac
    81301 tggaaatcca tttgacttct acagaaatct ccgcgtgact aatccttcta attaccttta
    81361 tttctatgat tttggggatt atcaaatcat cggagctagt ccagaaagtt tagtttctgt
    81421 caaaaatggc atcgtgacaa ccaatccgat tgcagggacg cgaccaagag gggctacgga
    81481 tgaagaagac aagaccttgg cgactgacct cctctctgat gagaaggaaa cagcagaaca
    81541 tcgaatgttg gtagacttgg ggcgtaacga tattggccgc atctctgaaa cggccagtgt
    81601 ccaagttact aagtatatga aggtggagct cttccgctac gtcatgcatt tgaccagcgt
    81661 ggtcaagggg cgtttgcttc cagaactcac ggccatggat gccttgaaag ctacacttcc
    81721 tgctggaacc gtttctggag caccaaagat tcgggcgatg agacgcatct atgaactgga
    81781 aacggaaaaa cggggcgtat atgcaggagc aatcggctac ttgtctgcga cgggtgatat
    81841 ggatttggcc attgccatcc gaaccatgat tctcaaaaat caaagagcct atgtgcaggc
    81901 tggggcaggg attgtctacg actctatcgc ccaaaacgaa taccaagaaa ccattaacaa
    81961 agcaaaatct atgactagaa ttggagaact aagaccatga ttttattgat tgacaactat
    82021 gattctttta cctataactt ggcccaatac attgggaatt ttgcagaagt tcaggttctg
    82081 agaaatgatg attccaagct gtatgaagaa gctgaaaaag cagatggtct ggtcttttct
    82141 cctggtcctg gttggccagt tgatgctgga aagatggaag acatgattcg tgattttgca
    82201 ggcaagaagc cgattcttgg gatttgtttg ggccaccaag ccattgcaga agtctttggt
    82261 ggtaagctag gtttggctcc aaaagtcatg catgggaaac agagcaatat caactttgaa
    82321 gcgccatctg ttttgtatca aggtattgag gaaggacgtg cggtcatgcg ttatcacagt
    82381 attttgattg aggaaatgcc agaagacttt gaagtgacag ctcgttcgac tgatgaccaa
    82441 gccatcatgg ggattcaaca taaaaaccta ccgatttatg gcttccagta ccatccagag
    82501 agcattggaa cgccagacgg cttgtcttct attcggaatt ttatcgagaa ggttgtaaag
    82561 tgaggaaact aggatgaaag agattattga aaaactagca aaatttgaaa atttatcagg
    82621 tgtggaaatg acggatgtca ttgagcgtat cgtaactggg cgtgtaactg aagcgcagat
    82681 tgcttctctc ctcttagctc ttaagatgaa gggggaaaca cctgaagaac gcacagccat
    82741 tgcccaagtc atgagaggac atgcccagca tattccaact gagattcatg atgccatgga
    82801 caactgtggt acaggtgggg acaagtcttt cagttttaat atttccacaa ctgcagcctt
    82861 tgtcttggct ggtggcggta ttcacatggc caagcatggt aaccgctcga tttcttctaa
    82921 atctggttcc gcagatgtcc tcgaagcctt gggaatcaat cttgacctca aaccagctga
    82981 actaggtaag gtctttgata aaactggaat cgtctttctc ttcgctaaaa atatgcaccc
    83041 agctatgaaa tacatcatgc cagctcgttt ggaattggga attccaacga ttatgaactt
    83101 gactggtcca ctgattcatc caatggcttt agaaacacag cttcttggaa ttagtcgtcc
    83161 agaactccta gaaagtacag ctcaggtttt gaaaaatatg ggtcgcaaac gtgccatcgt
    83221 ggttgctgga ccagaagggt tggatgaagc tggcttgaac ggaacaacca agattgcact
    83281 tcttgaaaat ggcgaaatca gcttgtcaag ctttactcca gaggatttgg gaatggaagg
    83341 ctatgctatg gaagatattc gtggtgggaa tgctcaggaa aatgcagaaa ttttgcttag
    83401 cgttctgaaa aacgaagcaa gtccattctt ggaaacgaca gtcttgaatg ctggtcttgg
    83461 tttctatgct aatggtaaga ttgatagcat caaggaagga gttgccttgg ctcgtcaagt
    83521 gattgctaga ggcaaggccc ttgaaaaact cagactgtta caggagtacc aaaaatgagt
    83581 caggaatttt tagcacgaat cttagagcag aaggcgcgtg aggtggagca gatgaagctg
    83641 gagcaaatcc agcctctgcg ccagacctat cgcttggcag aatttttgaa gaatcatcag
    83701 gaccgcttgc aggtaatcgc tgaggtcaag aaagctagcc ctagtttggg agatatcaat
    83761 ctcgatgtgg atattgtgca acaggcccag acttatgaag aaaacggagc agtgatgatt
    83821 tcggtgttga cagatgaggt tttctttaaa gggcatttgg attatctacg ggaaatttcc
    83881 agtcaggtag agattccgac gctcaacaaa gactttatca tagatgaaaa gcaaatcatc
    83941 cgcgctcgca atgcaggtgc gacagttatc ttgctcattg tggcagcctt gtccgaagaa
    84001 cgcctcaagg aactgtatga ctacgcgaca gagcttggtc tggaagtctt agtggagact
    84061 cacaatctag ctgaactaga ggtagcccac agacttggtg ctgagattat tggggtcaac
    84121 aaccgcaact tgactacctt tgaggtcgac ttgcagacca gtgtagattt agccccttac
    84181 tttgaggaag gtcgctatta catttctgaa tctgccattt tcacagggca ggatgcggaa
    84241 cgactagccc catactttaa cggaattttg gtagggacag ctcttatgca ggcagaaaat
    84301 gtggcccaga gaatcaagga gttgcagatt gacaaaggtt aaaatttgtg gactatcgac
    84361 caaagaagcg gtggaaacag ccgtttcagc aggagccgac tatatcggtt ttgtctttgc
    84421 acctagtaaa agacaggtga ctttagaaga ggcagctgtg ttggcaaagc ttattcctgc
    84481 agatgtgaaa aaggttggag tatttgtttc accaagtcgg gtagaactgc tggaagcgat
    84541 tgacaaagtt ggcttggact tggttcaagt tcacggtcag gtggcagatg atttatttga
    84601 gaatttgcct tgtgccagta ttcaggctgt gcaggtagat ggaaatgggc atgtccccaa
    84661 ttctcaggca gattatctac tctttgatgc ccctgtggca ggaagtggcc agccctttga
    84721 ttggggtcaa ctggatacga ctggactagc acagcccttc tttatcgcag gtggccttaa
    84781 tgaagataat gtagtaaaag caattcaaca ttttactccc tatgcagtag atgtatcgag
    84841 cggagtggag acagatggac aaaaagatca tgaaaagatt agaagattta tagagagggt
    84901 aaagcatggc atatcaggaa ccaaataaag atggatttta cggaaaattc ggcggacgtt
    84961 ttgtcccaga aacattgatg acagcagttt tggagttgga gaaggcctat cgtgaaagtc
    85021 aggcagaccc aagtttccaa gaggaattaa accaactctt gcgccagtat gtggggcggg
    85081 aaactcctct ttactacgca aaaaacttga cccagcatat tggcggagcc aagatttatc
    85141 tcaaacggga agaccttaac catacaggag cccacaagat taacaatgcc ttaggacaag
    85201 tttggcttgc caaacgcatg ggtaaaaaga aaattatcgc agaaaccggt gctggtcagc
    85261 acggtgtggc aactgcaact gctgcggccc tctttaacat ggaatgtacc atctacatgg
    85321 gtgaggaaga tgtcaaacgc caagccctca atgtcttccg catggagctt ttgggagcca
    85381 aggtcgaggc tgtaacagat ggttcgcgcg tgctcaagga tgcggtcaat gcagcccttc
    85441 gttcatgggt ggctaatatc gacgataccc actatatcct tggttctgcc ttggggcctc
    85501 atccatttcc agaaatcgtt cgtgacttcc aaagtgtcat cggtcgcgaa gctaaacaac
    85561 agtatcgcga tatgacaggt caaaatctgc ccgatgctct agtagcctgt gttggtggtg
    85621 gatctaatgc tattgggctc ttccatccct ttgtagaaga tgagtcagta gctatgtatg
    85681 gaactgaagc agcagggctt ggtgtggata cggagcacca cgctgctacc ttgaccaagg
    85741 gtcgtccggg tgttcttcac ggttctctca tggatgtgct ccaagatgcc catggtcaaa
    85801 ttcttgaagc cttctctatc tcagcaggtt tggactatcc tggtatcggt ccagagcatt
    85861 ctcactacca cgatattaaa cgtgccagct atgtccctgt gacagacgaa gaagccttgg
    85921 aaggattcca actcttgtct cgtgtggaag ggattatccc agctttggaa tctagccatg
    85981 ctatcgcttt tgcggtgaaa ttggccaaag aacttggacc agaaaagtct atgattgtct
    86041 gcctatcagg tcgtggggac aaggatgtgg ttcaagtcaa agaccgcttg gaagcagatg
    86101 cagcaaagaa gggagaagct catgcctaag acactaacag aaaaattgaa tgctattaaa
    86161 gcagctggaa aaggaatttt tgttccctat atcatggctg gtgaccacga gaaaggtttg
    86221 gacggtcttg ctgaaacaat tcacttttta gaagatttgg gtgtctctgc aattgaagtg
    86281 ggtattccct tttcagaccc tgttgcagat ggacctgtta tcgaagaagc tggcttgcgc
    86341 agtttagccc acgggacctc tacccaggct ttagttgaaa ccttgaaaac cattgaaaca
    86401 gagattccac tggtcatcat gacctacttc aaccccctct ttcagtacgg tgtggagaac
    86461 tttgtcaaag atctggctga tacagctgtg aagggcttga ttatcccaga cttgcctcat
    86521 gaacatgcca actttgtaga accatttttg gcagatacag atatcgcctt gattccttta
    86581 gtaagcttga ccacaggaat tgagcgccag aaagagttga ttgaaggggc ggagggattc
    86641 atctatgccg ttgccatcaa tggagtgaca gggaaatcag gcaattaccg tgcagatttg
    86701 gacaagcact tggcgcaact tcatcaagtg gccgacatcc cagtcttgac aggttttggt
    86761 gtatctagtc aagccgatct ggaacgcttc aatgcggtgt cagatggtgt tatcgtcggt
    86821 tcgaaaatag taaaagctct ccaccaagga gagccgattc aggactttat caaacaagca
    86881 gtagcttacc aaaaataatc aaacaagtag caagtaagag gaaaggcacg aaaggaagtc
    86941 tttccttttt cttttgcagg cgaaaggcta gttttatagt gaattgaatc tggaatatta
    87001 cactacggtt cctaaaatat tttaagaaag tgatttgaat ttcccaataa atttgttcag
    87061 tttttaattg attttactat agaagatata attttctaaa ttactctgac acagaacttt
    87121 aagaaaaagc taattattgt agtaatttct ttaagaaaat gatataattc attaaaaagt
    87181 atttggagga ggaagaatta tgttgaatca ggatctcttt gattcgcttg aggcacaaaa
    87241 aattgtagat actttgatga aagggcaaaa agattatgta gatgaacgtc tagaaaaaag
    87301 agagacaatg atagtgtcga atggttatgc atggacgtga cctaatcata ttgatactgc
    87361 atttgcatca gcagatttgt ttgagtataa attacaatta gcaggacaga cttggggata
    87421 tttagaattt gaaacaaata cagaaaaata tgggaaagta ttgttaatta taaagggtaa
    87481 gaagcgactt acgaaccaat ttcctttggt acaaaaaaat aagagtggct acttatttga
    87541 atatgctcag atgaatacac tttatcttaa tcaacattct tcctacaaaa atgatgaaga
    87601 tagtcattcc tttccaattc agatggagtt agtttctgat gaaatgattc aagaaattga
    87661 acaagctact aaaaattcga atatcgaaaa atttatgatt ttaacttatg aggcggactc
    87721 agaaaacaat attatatctg tagatgttgt tatgcctgat gcacgaactg gtcagttaca
    87781 cttgattcaa gatttgtctg agtatattca atcaagttcg taccatttcg aagaagctaa
    87841 atatcaagat attcctaatt tttcagaatt atcggaaaca gaagattttg aaattattcc
    87901 aagaatagaa aaacaagaag gtcaaaagta gtaaggagta tgtaaatgtt taatggtcgg
    87961 gtattgaaag aattacggct gttaaatggt ttaagtagag cagaattagc tcagagaatt
    88021 aatttaacgg aacaagccat ttggcagttt gagtccaacg aaacgaaacc taaattatca
    88081 accaaaatgc atttggccaa ccaatttcat gttgatttaa cttattttga acaggaagaa
    88141 gagagcattc gatttgattc ttctgtaatt gcctttagaa atgcagacct agcaacacgg
    88201 aaaacaatag atattcaaac tatgtattta cataaggtag atagtttgat tgattatttt
    88261 gaaagttttg taattatacc taatattata attcatgacc taagtaatgt agtgagtgaa
    88321 tcttatcata agggagaatc cattgaggaa ttggctcttt atgccaggga aaaattaggt
    88381 atttcaaaag ataatcatga tttgctttat aaattagaac gttcaggcat ctatatcgtg
    88441 gaacgattaa ttaatggcca agctgatgct tatagcgcat ggtcaaaatt gggaagacct
    88501 tatattgtgt tgggaacgaa taaatcatct gtacgtcgaa attttgactt agctcatgag
    88561 ctaggacata ttcttttaca taaatataaa gatatgaatg aagatggcga tcgtttggag
    88621 caagaagcaa attattttgc atcatgtttt ttattgccaa aagaagagtt tttagtcaaa
    88681 tttgaagaga gggttggcaa gcgtgtcagc aatcctgata gttatatttt attgaagtcg
    88741 gatttgaatg tttcgataca ggctttagag tatcgagctt ttaagttagg attattgact
    88801 ccaaagcaac attcttactt ttatcgtcaa attgcgcaaa aaggttacaa aatgattgaa
    88861 cctttggatg atcaaatttt tgttaaaaaa ccaagcaaag taaagagtat tctggacgtt
    88921 gttttgagta atcatctagt cagtctagcg actataatgt ctaaacaaag tattcgttta
    88981 cagtttataa gcgaaatatt ttcagtcgaa atgaaatttt ttgatcagta tcaagaagat
    89041 agaagaacag atcgatttga taacatcatc cctttgtaca aaagaaataa tttataattt
    89101 aactgtgaaa taatttcatg aaggacatat ggcagaaatt ggattttatc agacaagcag
    89161 tagcttacca aaaataatca cacaagcagc aagtaagagg aaaggcacga aaggaagtct
    89221 ttcctttttc ttttgcagga gaaaggccag gatacccgtc gcagaagcga actgaatcaa
    89281 gatcagtaac tccgttacgc taaagacgag agcgcaagaa gctaaaaaaa ggaaatcccc
    89341 tgcacccatg cggatatcga taaaatgagc caaaattcca agtatgagga aggagaccat
    89401 gaccagattc cagccagagg aagctattag gattaggtgg aaagtcatcc agaccagtaa
    89461 gggatattcc tgatggcgaa agtcgtagat gcccaaggtc aaaccagcag tgattaggat
    89521 gacttgactc aaggaaagta attcccaaga gtaaagcaga aagaggagtc ctaagcctag
    89581 ttcaaagagg gcataccaga caggatagcg gaccttgcag tagcgacagc aaaagcgatt
    89641 gaagacctgt gagagaatcg gaatcaaatc taagggacgc aagcgagtct gacaggaatc
    89701 gcagtgactg gctgaactga taatggattg ctctggaaaa cggtcaatga ccaaaccaag
    89761 aaaggaagcg agaatgctcc cgacgagaaa aaaataaaaa tcaatcatac ttatctattc
    89821 gtaaaaaatg ggagaaatag tataatggag aaacatagat aagatggtga ggaaaagatg
    89881 acaattcgtt ttgaagaaaa ggtgagtata gaaaacgctc aatttgtatg ccagtggtcc
    89941 aactccctag gcaaatcctt tcaagaacaa tggatgggac caaggattcc ttttctactg
    90001 acccttcaag ccttggaagg agtcttttca atctttgatg aacaagagtt tgtggcactt
    90061 atccagaaaa tcaggctaga agacagcaat cttcatatcg ggagattttt tatcaacccc
    90121 cagaaacagg agcaagactt aggtagccag gctttaagga aatttgttag tttagcattt
    90181 gaaaatagag atatagacag tatttctcta aatgtcttcg aggcaaatca aagagctcag
    90241 aatctttacc aaaaagaagg atttgaaatc gtttaaatgg ttgaagcacc tgtacgaaaa
    90301 tatagtagat tgaaac
//
LOCUS       DAVEHY010000004        82196 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVEHY010000004 DAVEHY010000000
VERSION     DAVEHY010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82196
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.004"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            371..598
                     /locus_tag="VUZ44_000333"
     CDS             371..598
                     /locus_tag="VUZ44_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319307.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3798
                     /gene="nanA"
                     /locus_tag="VUZ44_000334"
     CDS             886..3798
                     /gene="nanA"
                     /locus_tag="VUZ44_000334"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU0319308.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNDQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGEMGKGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEII
                     GIAKGSIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKG
                     SDSLVTLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4813..5265
                     /locus_tag="VUZ44_000335"
     CDS             4813..5265
                     /locus_tag="VUZ44_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU0319309.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGEVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5284..6621
                     /locus_tag="VUZ44_000336"
     CDS             5284..6621
                     /locus_tag="VUZ44_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU0319310.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDFKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6700..7584
                     /locus_tag="VUZ44_000337"
     CDS             6700..7584
                     /locus_tag="VUZ44_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU0319311.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7584..8417
                     /locus_tag="VUZ44_000338"
     CDS             7584..8417
                     /locus_tag="VUZ44_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU0319312.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8612..9715
                     /locus_tag="VUZ44_000339"
     CDS             8612..9715
                     /locus_tag="VUZ44_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU0319313.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            9889..10587
                     /locus_tag="VUZ44_000340"
     CDS             9889..10587
                     /locus_tag="VUZ44_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU0319314.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            10606..12123
                     /locus_tag="VUZ44_000341"
     CDS             10606..12123
                     /locus_tag="VUZ44_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU0319315.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            12248..13576
                     /locus_tag="VUZ44_000342"
     CDS             12248..13576
                     /locus_tag="VUZ44_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0319316.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            13828..14694
                     /locus_tag="VUZ44_000343"
     CDS             13828..14694
                     /locus_tag="VUZ44_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU0319317.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            14710..15549
                     /locus_tag="VUZ44_000344"
     CDS             14710..15549
                     /locus_tag="VUZ44_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU0319318.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            15821..16273
                     /locus_tag="VUZ44_000345"
     CDS             15821..16273
                     /locus_tag="VUZ44_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU0319319.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            16370..16714
                     /locus_tag="VUZ44_000346"
     CDS             16370..16714
                     /locus_tag="VUZ44_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319320.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            16998..17642
                     /locus_tag="VUZ44_000347"
     CDS             16998..17642
                     /locus_tag="VUZ44_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU0319321.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            17811..18728
                     /locus_tag="VUZ44_000348"
     CDS             17811..18728
                     /locus_tag="VUZ44_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU0319322.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            18746..19630
                     /locus_tag="VUZ44_000349"
     CDS             18746..19630
                     /locus_tag="VUZ44_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU0319323.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(19646..20497)
                     /locus_tag="VUZ44_000350"
     CDS             complement(19646..20497)
                     /locus_tag="VUZ44_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU0319324.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            20697..22754
                     /gene="pbp2b"
                     /locus_tag="VUZ44_000351"
     CDS             20697..22754
                     /gene="pbp2b"
                     /locus_tag="VUZ44_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU0319325.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            22765..23361
                     /gene="recR"
                     /locus_tag="VUZ44_000352"
     CDS             22765..23361
                     /gene="recR"
                     /locus_tag="VUZ44_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU0319326.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            23537..24580
                     /locus_tag="VUZ44_000353"
     CDS             23537..24580
                     /locus_tag="VUZ44_000353"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU0319327.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            24664..26037
                     /locus_tag="VUZ44_000354"
     CDS             24664..26037
                     /locus_tag="VUZ44_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU0319328.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            26024..26635
                     /locus_tag="VUZ44_000355"
     CDS             26024..26635
                     /locus_tag="VUZ44_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU0319329.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            26726..27430
                     /locus_tag="VUZ44_000356"
     CDS             26726..27430
                     /locus_tag="VUZ44_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU0319330.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            27649..29022
                     /gene="ftsA"
                     /locus_tag="VUZ44_000357"
     CDS             27649..29022
                     /gene="ftsA"
                     /locus_tag="VUZ44_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU0319331.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            29039..30298
                     /gene="ftsZ"
                     /locus_tag="VUZ44_000358"
     CDS             29039..30298
                     /gene="ftsZ"
                     /locus_tag="VUZ44_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU0319332.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            30303..30974
                     /locus_tag="VUZ44_000359"
     CDS             30303..30974
                     /locus_tag="VUZ44_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU0319333.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            30984..31523
                     /locus_tag="VUZ44_000360"
     CDS             30984..31523
                     /locus_tag="VUZ44_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU0319334.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            31523..31786
                     /locus_tag="VUZ44_000361"
     CDS             31523..31786
                     /locus_tag="VUZ44_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU0319335.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            31783..32568
                     /locus_tag="VUZ44_000362"
     CDS             31783..32568
                     /locus_tag="VUZ44_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU0319336.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            32577..33365
                     /gene="divIVA"
                     /locus_tag="VUZ44_000363"
     CDS             32577..33365
                     /gene="divIVA"
                     /locus_tag="VUZ44_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU0319337.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            33713..36505
                     /locus_tag="VUZ44_000364"
     CDS             33713..36505
                     /locus_tag="VUZ44_000364"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU0319338.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            36908..37288
                     /locus_tag="VUZ44_000365"
     CDS             36908..37288
                     /locus_tag="VUZ44_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319339.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            37482..37772
                     /locus_tag="VUZ44_000366"
     CDS             37482..37772
                     /locus_tag="VUZ44_000366"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319340.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            37823..38515
                     /locus_tag="VUZ44_000367"
     CDS             37823..38515
                     /locus_tag="VUZ44_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU0319341.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            38568..40979
                     /locus_tag="VUZ44_000368"
     CDS             38568..40979
                     /locus_tag="VUZ44_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU0319342.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAPHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            41229..41930
                     /locus_tag="VUZ44_000369"
     CDS             41229..41930
                     /locus_tag="VUZ44_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319343.1"
                     /translation="MAYIDMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            41932..44640
                     /locus_tag="VUZ44_000370"
     CDS             41932..44640
                     /locus_tag="VUZ44_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU0319344.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVDLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(44736..45227)
                     /gene="tpx"
                     /locus_tag="VUZ44_000371"
     CDS             complement(44736..45227)
                     /gene="tpx"
                     /locus_tag="VUZ44_000371"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU0319345.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLSRAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(45350..46279)
                     /gene="psaA"
                     /locus_tag="VUZ44_000372"
     CDS             complement(45350..46279)
                     /gene="psaA"
                     /locus_tag="VUZ44_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU0319346.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(46311..47159)
                     /locus_tag="VUZ44_000373"
     CDS             complement(46311..47159)
                     /locus_tag="VUZ44_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU0319347.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(47156..47878)
                     /locus_tag="VUZ44_000374"
     CDS             complement(47156..47878)
                     /locus_tag="VUZ44_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU0319348.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            48178..50070
                     /gene="pepO"
                     /locus_tag="VUZ44_000375"
     CDS             48178..50070
                     /gene="pepO"
                     /locus_tag="VUZ44_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU0319349.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPILSLLKEFQELETFADF
                     IAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(50193..50822)
                     /locus_tag="VUZ44_000376"
     CDS             complement(50193..50822)
                     /locus_tag="VUZ44_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU0319350.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            51818..54040
                     /locus_tag="VUZ44_000377"
     CDS             51818..54040
                     /locus_tag="VUZ44_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU0319351.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            54070..54513
                     /locus_tag="VUZ44_000378"
     CDS             54070..54513
                     /locus_tag="VUZ44_000378"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU0319352.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(54552..54966)
                     /locus_tag="VUZ44_000379"
                     /pseudo
     CDS             complement(54552..54966)
                     /locus_tag="VUZ44_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(54985..55398)
                     /locus_tag="VUZ44_000380"
     CDS             complement(54985..55398)
                     /locus_tag="VUZ44_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319353.1"
                     /translation="MKKLYRIHFIAISVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(55529..56041)
                     /locus_tag="VUZ44_000381"
     CDS             complement(55529..56041)
                     /locus_tag="VUZ44_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319354.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGATDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLNAIGA
                     LFVWNDEEVR"
     gene            complement(56218..56868)
                     /locus_tag="VUZ44_000382"
     CDS             complement(56218..56868)
                     /locus_tag="VUZ44_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU0319355.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            56980..57822
                     /locus_tag="VUZ44_000383"
     CDS             56980..57822
                     /locus_tag="VUZ44_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU0319356.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQSLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            57898..58335
                     /locus_tag="VUZ44_000384"
     CDS             57898..58335
                     /locus_tag="VUZ44_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU0319357.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            58403..58705
                     /locus_tag="VUZ44_000385"
     CDS             58403..58705
                     /locus_tag="VUZ44_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319358.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(58796..59869)
                     /locus_tag="VUZ44_000386"
     CDS             complement(58796..59869)
                     /locus_tag="VUZ44_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU0319359.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            60025..60702
                     /locus_tag="VUZ44_000387"
     CDS             60025..60702
                     /locus_tag="VUZ44_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0319360.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            60695..61669
                     /locus_tag="VUZ44_000388"
     CDS             60695..61669
                     /locus_tag="VUZ44_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU0319361.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(61718..63661)
                     /gene="thrS"
                     /locus_tag="VUZ44_000389"
     CDS             complement(61718..63661)
                     /gene="thrS"
                     /locus_tag="VUZ44_000389"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU0319362.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEARKIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(63719..63895)
                     /locus_tag="VUZ44_000390"
                     /pseudo
     CDS             complement(63719..63895)
                     /locus_tag="VUZ44_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(64473..64673)
                     /locus_tag="VUZ44_000391"
     CDS             complement(64473..64673)
                     /locus_tag="VUZ44_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319363.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            64912..65541
                     /locus_tag="VUZ44_000392"
     CDS             64912..65541
                     /locus_tag="VUZ44_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU0319364.1"
                     /translation="MKLAVIAANGQVGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            65682..65951
                     /gene="rpsO"
                     /locus_tag="VUZ44_000393"
     CDS             65682..65951
                     /gene="rpsO"
                     /locus_tag="VUZ44_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU0319365.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            66685..67299
                     /locus_tag="VUZ44_000394"
     CDS             66685..67299
                     /locus_tag="VUZ44_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU0319366.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(67592..68341)
                     /locus_tag="VUZ44_000395"
     CDS             complement(67592..68341)
                     /locus_tag="VUZ44_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU0319367.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            68474..70810
                     /locus_tag="VUZ44_000396"
     CDS             68474..70810
                     /locus_tag="VUZ44_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU0319368.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            70912..71589
                     /locus_tag="VUZ44_000397"
     CDS             70912..71589
                     /locus_tag="VUZ44_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU0319369.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAERILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            71576..72373
                     /locus_tag="VUZ44_000398"
     CDS             71576..72373
                     /locus_tag="VUZ44_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU0319370.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            72390..73493
                     /locus_tag="VUZ44_000399"
     CDS             72390..73493
                     /locus_tag="VUZ44_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU0319371.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSLGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            73749..74768
                     /gene="galE"
                     /locus_tag="VUZ44_000400"
     CDS             73749..74768
                     /gene="galE"
                     /locus_tag="VUZ44_000400"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU0319372.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKVMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            74770..75735
                     /locus_tag="VUZ44_000401"
     CDS             74770..75735
                     /locus_tag="VUZ44_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0319373.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRISREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(75786..75992)
                     /locus_tag="VUZ44_000402"
     CDS             complement(75786..75992)
                     /locus_tag="VUZ44_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU0319374.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            76044..76520
                     /locus_tag="VUZ44_000403"
     CDS             76044..76520
                     /locus_tag="VUZ44_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU0319375.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            76529..77200
                     /locus_tag="VUZ44_000404"
     CDS             76529..77200
                     /locus_tag="VUZ44_000404"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU0319376.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            77331..77669
                     /locus_tag="VUZ44_000405"
     CDS             77331..77669
                     /locus_tag="VUZ44_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU0319377.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            77672..78301
                     /locus_tag="VUZ44_000406"
     CDS             77672..78301
                     /locus_tag="VUZ44_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU0319378.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            78541..79692
                     /locus_tag="VUZ44_000407"
     CDS             78541..79692
                     /locus_tag="VUZ44_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU0319379.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            80005..80754
                     /gene="truA"
                     /locus_tag="VUZ44_000408"
     CDS             80005..80754
                     /gene="truA"
                     /locus_tag="VUZ44_000408"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU0319380.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            80744..81517
                     /locus_tag="VUZ44_000409"
     CDS             80744..81517
                     /locus_tag="VUZ44_000409"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU0319381.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            81495..81956
                     /locus_tag="VUZ44_000410"
     CDS             81495..81956
                     /locus_tag="VUZ44_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU0319382.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        24514 a        15012 c        18430 g        24240 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 attaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaatttggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggaataa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg atcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ccccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagagat gggcaaagga
     3301 gttattggct tggagttcga ctcagaagta ttggtcaaca aggctccaac ccttcaattg
     3361 gcaaatggta aaacagcgac tttcctaacc cagtatgata gcaagacctt gttgtttgca
     3421 gtagataagg aagatatcgg acaggaaatt attggtatag ctaaaggaag catcgaaagt
     3481 atgcataatc ttcctgtaaa tctagcaggt gccagagttc ctggcggagt aaatggtagc
     3541 aaagcagcgg tgcatgaagt tccagaattt acagggggag ttaatggtac agagccagct
     3601 gttcatgaaa tcgcagagta taagggatct gattcgcttg taactcttac tacaaaagaa
     3661 gattatactt acaaagctcc tcttgctcag caggcacttc ctgaaacagg aaacaaggag
     3721 agtgacctcc tagcttcact aggactaaca gctttcttcc ttggtctgtt tacgctaggg
     3781 aaaaagagag aacaataaga gaagaattct aaacatttga ttttgtaaaa atagaaggag
     3841 atagcaggtt ttcaagcctg ctatcttttt ttgatgacat tcaagctgat acgaaatcat
     3901 aagaggtctg aaactacttt cagagtagtc tgttctataa aatatagtag attgaaataa
     3961 gatgtgaaca actctatcag gaaagtcaaa ttaatttata gaaaaatttt agcagtcaag
     4021 gtgtactgtt atagattcaa tatattatgc gactattaac cttatcttct cctaaaattg
     4081 actttcttgt tttcttatct tgtctactcg aaacaagtat tgtaagaatt tgattatttt
     4141 tgaaagtact tttaatatac ttgatatagt taaaaaagat ttgaaactaa attccaaatt
     4201 agaaaaagac ttgaaatact aaaaaaaaaa agtatactct aattgaaaac ggtaacaaaa
     4261 ctaatttaga gaatgaaata tagagtattt ctctcttaaa agtttttggt gaaacgagat
     4321 gtagaaagga gatttagcca aagagtctat tagtgctaga ataatagatt agaattattt
     4381 tagaaaaacg aagtgagcag cttataaatt caagtcccca aatagattca tactagtatc
     4441 ttttgcaaaa aataaagggc gatttccttc atgaatatca atttcatcta taaggaaggt
     4501 agctaattga actaacttat ttattctgtt tgtcgctaga aaaatcagac ctccttgtga
     4561 agattgagga gatactgaat gaaaatcaaa gaagaaacta gcaagctagt agcagattgc
     4621 ccaaaacacc gctttgaggt tgtagataag actgacgtat ataatccaag gtgaagcgac
     4681 tgtggtttga agagattttc aaagagtata ggctagagag tagtgttttt atgtccttct
     4741 agtagaaaat gctagacaga agaatgggga acttggatag gaaaaataga ttgagaaagg
     4801 aggttagaag agatgattat tacaaaaatt agccgtttag gaacttatgt gggagtaaat
     4861 ccacattttg caacattaat agatttttta gaaaaaacag gactagaaaa tttaacagaa
     4921 ggttcgattg ctatcgatgg taatcgattg tttgggaatt gctttactta tctagcagat
     4981 ggtcaagcag gagccttctt tgaaacccac caaaaatatt tggatattca tttagtgctg
     5041 gaaaacgaag aagccatggc tgtgacgtcg ccggaaaatg taagcgttac ccaagagtat
     5101 gatgaagaga aggatattga attatacaca ggggaagtgg aacagttagt tcatttgaga
     5161 gctggcgaat gcctcatcac ttttccagaa gatttacatc aacccaaggt tcgtataaat
     5221 gatgaacctg tgaaaaaagt tgtctttaaa gttgcgattt cttaatgtag aaagagaaga
     5281 acgatgaaaa aaatgagaaa gtttttatgt ctagctggaa ttgcgctagc ggctgttgcc
     5341 ttggtagctt gttcaggaaa aaaagaagct acaactagta ctgaaccacc aacagaatta
     5401 tctggtgaga ttacaatgtg gcactccttt actcaaggac cccgtttaga aagtattcaa
     5461 aaatcagcag atgctttcat gcaaaagcat ccaaaaacga aaatcaagat tgaaacattt
     5521 tcttggaatg acttctatac taaatggact acaggtttag caaatggaaa tgtgccagat
     5581 atcagtacag ctcttcctaa ccaagtaatg gaaatggtca actcagatgc tttggttccg
     5641 ctaaatgatt ctatcaagcg tattggacaa gataaattta acgaaactgc cttaaatgaa
     5701 gcaaaaatcg gagatgatta ctactctgtt cctctttatt cacatgcaca agtcatgtgg
     5761 gttagaacag atttgttaaa agaacataat attgaggttc ctaaaacttg ggatcaactc
     5821 tatgaagctt ctaaaaaatt gaaagaagct ggagtttatg gcttgtctgt tccgtttgga
     5881 acaaatgact taatggcaac acgtttcttg aacttctacg tacgtagtgg tggaggaagc
     5941 ctcttaacaa aagattttaa agcagacttg acaagccaac ttgctcaaga tggtattaaa
     6001 tactgggtta aattgtataa agaaatctca cctcaagatt ctttgaactt taatgtcctt
     6061 caacaagcta ccttgttcta tcaaggaaaa acagcatttg actttaactc tggcttccat
     6121 atcggaggaa ttaatgccaa cagtcctcaa ttgattgatt cgattgatgc ttatcctatt
     6181 ccaaaaatca aagagtctga taaagaccaa ggaattgaaa cctcaaacat tccaatggtt
     6241 gtttggaaaa attcaaaaca tccagaagtt gctaaagcat tcttagaagc actttataat
     6301 gaagaagact acgttaaatt ccttgattca actccagtag gtatgttgcc aactattaag
     6361 gggattagcg attctgcagc ctataaagaa aatgaaactc gtaagaagtt taaacatgct
     6421 gaagaagtaa ttactgaagc tgttaaaaaa ggtactgcta ttggttatga aaatggacca
     6481 agtgtacaag ctggtatgtt gactaaccaa cacattattg aacaaatgtt ccaagatatc
     6541 attacaaatg gaacagatcc tatgaaagca gcaaaagaag cagaaaaaca attaaatgat
     6601 ttatttgagg ctgttcagta gatgtaaaag actagaaaat aggtgggcta gtgagctgaa
     6661 aagctctagc ccaatcttgt aaaagaaggg agaaggagaa tggttaaaga acgtaattta
     6721 actcgctgga tatttgtttt gccagctatg attatcgtag gattactctt tgtttatccg
     6781 tttttctcga gtatttttta tagctttacc aataagcatt tgattatgcc taattataaa
     6841 tttgttggtt tggctaacta taaagctgtg ctatcagatc ccaacttctt taatgcgttc
     6901 tttaattcaa ttaagtggac cgttttctca ttagttggtc aagttttagt agggtttgta
     6961 ttggctttag ctcttcacag agtacgccac ttcaagaaat tatataggac cttattgatt
     7021 gttccttggg catttcctac catcgttatt gccttttctt ggcagtggat tctaaacggg
     7081 gtttatggct acttacctaa tctaatcgta aaattaggtt taatggaaca tacacctgca
     7141 tttttgacag atagtacatg ggcattccta tgtttggtgt ttatcaacat ttggtttgga
     7201 gcaccaatga ttatggttaa tgtgctttca gctttgcaaa cagtaccaga agaacaattt
     7261 gaggctgcta agatagatgg tgcttcaagt tggcaggtgt tcaagtttat cgtctttcca
     7321 catattaaag tggttgtagg acttctagtt gttttgagaa ctgtatggat ctttaataac
     7381 tttgacatta tctacctcat tactggtggt ggaccagcca atgctacaac gacgcttcca
     7441 atttttgctt acaacctggg ttggggaact aaattgttgg gtcgtgcttc agcagttaca
     7501 gtattgctct ttatcttctt ggtggcgatt tgctttatct actttgctat catcagtaag
     7561 tgggaaaagg agggtagaaa ataatgaaga agaaatccag tatttattta gatattctct
     7621 cacatgtact tttagttggt gcgaccatcg ttgcaatttt cccattggta tggattatca
     7681 tatcttctgt caaagggaaa ggggaattaa ctcagtatcc aacacgattt tggcctgaac
     7741 agtttacatt agattatttc actcatgtta tcaacgattt gcacttcatt gataacattc
     7801 gaaacagttt aatcattgcc ttggctacaa ccctcattgc gattattatt tctgctatgg
     7861 cagcctatgg tattgttcga ttctttccta aattgggagc aatcatgtcg agactactcg
     7921 tcattaccta tattttccca ccaattttgt tagcaattcc ctattcaatt gccattgcta
     7981 aagttgggtt aacaaatagt ttatttggct tgatgatggt ttatctatct tttagtgttc
     8041 catatgcagt ttggctctta gttggatttt tccaaacagt tccaattgga attgaagaag
     8101 cggctagaat tgatggtgca aataaatttg ttacgtttta taaagttgtg ctaccgattg
     8161 tagcaccagg tattgtagca acagctattt atacatttat caatgcttgg aatgaattcc
     8221 tgtatgcctt gattttgatt aacaatacag gaaagatgac agtagcagta gcccttcgtt
     8281 cacttaatgg ttcagaaata ctagactggg gagatatgat ggcagcgtct gttattgtag
     8341 ttcttccatc aattattttc ttctctatca tccaaaataa gattgcaagt ggattatcag
     8401 aaggatctgt gaagtaatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
     8461 gctgctcaaa gtacagcttt gaggttgcag ataaaactga cgaagtcagt aaccatacgc
     8521 acagtaaggc gacgttgacg cggtttgaag agattttcga agagtataag ttaaaattag
     8581 aaagtttatt caataataaa ggagaaaaaa catggttaaa tacggtgttg ttggagcagg
     8641 gtattttgga gctgaattgg ctcgctacat gcaaaagaat gatggagcag agattactct
     8701 tctctatgat ccagataatg cagaggcgat tgcagaagaa ttgggagcaa aagtagcaag
     8761 ttccttagat gagttggttt ctagcgatga agtagattgt gttatcgtcg caactccaaa
     8821 taatcttcat aaggaaccgg ttattaaggc tgcacagcat ggtaaaaatg ttttctgtga
     8881 aaaaccaatt gcgctttctt atcaagattg tcgcgagatg gtagatgcgt gtaaagaaaa
     8941 caatgtaacc tttatggcag gacatattat gaatttcttt aatggtgttc atcatgcaaa
     9001 agaactcatt aatcaaggag ttatcggaga cgttctatat tgtcatacag ctcgtaatgg
     9061 ttgggaagaa caacaaccgt cagtgtcatg gaaaaaaatt cgtgaaaaat caggtggtca
     9121 cttgtatcac cacatccatg aattggattg cgttcaattc cttatggggg gcatgcctga
     9181 aactgtaacc atgacaggtg gaaatgtggc ccatgaaggt gaacatttcg gtgatgaaga
     9241 tgatatgatt tttgtcaata tggaattttc taataagcgt tttgccttgt tagaatgggg
     9301 ttcagcttat cgttggggtg aacattatgt cttaatccaa ggaagcaaag gtgccatccg
     9361 cttagactta ttcaactgta aaggaactct taagctagat gggcaagaaa gctatttctt
     9421 gattcacgaa tcgcaagaag aagatgatga tcggactcgt atctatcata gtacagagat
     9481 ggatggagca attgcttatg gtaaaccagg taaacgtact ccattatggc tatcatctgt
     9541 cattgataaa gaaatgcgct atctgcatga gattatggaa ggagccccag tatcagaaga
     9601 atttgcaaaa cttttgacag gtgaagctgc cctagaagca attgctactg cagatgcttg
     9661 tacccagtct atgtttgaag atcgcaaagt aaaattgtca gaaattgtaa aataaatttt
     9721 ggtattctcc tatttatagg tcgacttgct cctctgaaag tacttttaga ggagctgttt
     9781 gactttgcta gtttttgaaa ctgaaatcta ttatactaca aactattgaa agcgttttaa
     9841 ttttaaggta taataatctc atagaaataa agaaaaggag gaaagaggat gccacagatt
     9901 agcaaagaag ccttgattga gcaaatcaaa gatggaatca tcgtttcttg tcaggctctt
     9961 cctcatgaac cgctttatac agaagcggga ggggtgattc ccttgctggt caaagcggct
    10021 gagcaaggtg gagcagtcgg tatccgagca aacagtgttc gcgatatcaa ggaaattaag
    10081 gaagtcacta aacttccaat cattgggatt atcaaacgtg attatccacc tcaggaaccc
    10141 ttcatcacgg ctactatgaa agaagttgat gaattggcag aactggacat cgaggtgatt
    10201 gctctggatt gtaccaagcg tgaacgctac gatggtttgg aaattcaaga gttcattcgt
    10261 caggttaagg agaaatatcc taatcagctt ttgatggctg atactagtat cttcgaagaa
    10321 gggctagcag ctgtagaagc aggaattgac tttgtcggaa caaccttatc aggctacaca
    10381 tcctacagtc caaaagtaga cggtccagat tttgaattga ttaagaaact ctgtgatgcc
    10441 ggtgtagatg tcattgcaga aggaaaaatt catacaccag aacaagccaa acaaatcctt
    10501 gaatatggag tgcgaggcat cgttgttggt ggcgccatta ctagaccaaa agagattaca
    10561 gaacgcttcg ttgctagtct taaataagat gtgagaggga gttttatgtt taaagtttta
    10621 caaaaagttg gaaaagcttt tatgttacct atagctatac ttcctgcagc aggtctactt
    10681 ttggggattg gtggtgcact ttcaaaccca accacgatag caacttatcc aatactagac
    10741 aatagtattt ttcaatcaat attccaagta atgagctctg caggagaggt tgtattcagt
    10801 aatttgtcac tacttctctg tgtgggatta tgtattggct tagcgaaacg agataaagga
    10861 accgctgcgt tagcaggagt aactggttac ttagttatga ctgcaacgat caaagctttg
    10921 gtaaaacttt ttatggcaga aggatctgca attgatactg gagttattgg agcattagtt
    10981 gtcggaatag ttgccgtata tttgcacaac cgatataaca atattcaatt accttccgct
    11041 ttaggattct ttggaggttc acgcttcgtt cctattgtta catcgttctc ttctatcttg
    11101 attggctttg tcttctttgt tatttggcca cctttccaac aacttcttgt ttctacaggt
    11161 ggatatattt ctcaggcggg tccaattgga acttttctat atggattttt aatgagactt
    11221 tctggagcag taggcttaca tcatataatt taccctatgt tttggtatac tgaacttggt
    11281 ggtgttgaaa ctgttgcagg acaaacagtg gttggagctc aaaaaatatt ttttgctcaa
    11341 ttagccgatc cggcccattc tggattattt acagaaggaa caaggttttt tgcaggtcgt
    11401 ttctcaacaa tgatgttcgg tttaccggct gcctgtttag cgatgtacca tagtgttcct
    11461 aaaaatcgtc gtaaaaaata cgcgggtttg ttttttggag ttgctttaac atcttttatt
    11521 accggtatta cagaaccaat tgaatttatg tttctattcg tcagtccggt tctatatgtt
    11581 gttcacgcat tccttgatgg tgttagcttc tttattgcag acgtcttaaa tatttcaata
    11641 ggaaacacat tttcaggagg tgtaatcgat ttcactttat ttggaatttt gcaggggaac
    11701 gctaagacga attgggttct tcagattcca attggactta tttggagtgt tttgtattat
    11761 attattttta gatggttcat tactcaattc aacgttctaa cgccaggacg aggagaagaa
    11821 gtagattcta aagaaatttc tgaatccgca gattcaactt caaatactgc agattattta
    11881 aaacaggata gcctacaaat tatcagagcc ttgggtggat caaataatat agaagatgta
    11941 gatgcttgtg tgacacgttt acgtgtagct gtaaaagaag ttaatcaagt tgataaagca
    12001 cttttaaaac aaattggtgc agttgatgtc ttagaagtga agggtggcat tcaagcaata
    12061 tatggagcaa aagcaatctt atataaaaat agtattaatg aaattttagg tgtagatgat
    12121 taagtactta ctgacttaat aaaaaacaga ggagagtgat ggatgagtag gatgaaatga
    12181 aatcgcatac aagaaataaa gaactcatta tccaagttgg atacgcttat tacataggag
    12241 aatacaaatg aaatttagaa aattagcttg tacagtactt gcgggtgctg cggttcttgg
    12301 tcttgctgct tgtggcaatt ctggcggaag taaagatgct gccaaatcag gtggtgacgg
    12361 tgccaaaaca gaaatcactt ggtgggcatt cccagtattt acccaagaaa aaactggtga
    12421 cggtgttgga acttatgaaa aatcaatcat cgaagcgttt gaaaaagcaa acccagatat
    12481 aaaagtgaaa ttggaaacca tcgacttcaa gtcaggtcct gaaaaaatca caacagccat
    12541 cgaagcagga acagctccag acgtactctt tgatgcacca ggacgtatca tccaatacgg
    12601 taaaaacggt aaattggctg agttgaacga cctcttcaca gatgaatttg ttaaagatgt
    12661 caacaatgaa aacatcgtac aagcaagtaa agctggagac aaggcttata tgtatccgat
    12721 tagttctgcc ccattctaca tggcaatgaa caagaaaatg ttagaagatg ctggagtagc
    12781 aaaccttgta aaagaaggtt ggacaactga tgattttgaa aaagtattga aagcacttaa
    12841 agacaagggt tacacaccag gttcattgtt cagttctggt caagggggag accaaggaac
    12901 acgtgccttt atctctaacc tttatagcgg ttctgtaaca gatgaaaaag ttagcaaata
    12961 tacaactgat gatcctaaat tcgtcaaagg tcttgaaaaa gcaactagct ggattaaaga
    13021 caatttgatc aataatggtt cacaatttga cggtggggca gatatccaaa actttgccaa
    13081 cggtcaaaca tcttacacaa tcctttgggc accagctcaa aatggtatcc aagctaaact
    13141 tttagaagca agtaaggtag aagtggtaga agtaccattc ccatcagacg aaggtaagcc
    13201 agctcttgaa taccttgtaa acggatttgc agtattcaac aataaagacg acaagaaagt
    13261 cgctgcatct aagaaattca tccagtttat cgcagatgac aaagagtggg gacctaaaga
    13321 cgtagttcgt acaggtgctt tcccagtccg tacttcattt ggaaaacttt atgaagacaa
    13381 acgcatggaa acaatcagcg gctggactca atactactca ccatactaca acactattga
    13441 tggttttgct gaaatgagaa cactttggtt cccaatgttg caatctgtat caaatggtga
    13501 cgaaaaacca gcagatgctt tgaaagcctt cactgaaaaa gcgaacgaaa caatcaaaaa
    13561 agctatgaaa caatagtcct tagttattct ataaaaagta gttttttaaa gaacctaaga
    13621 gtgtataccc ccttttccct ctacacagat agtgtaagaa aagggggctt ttgtttaaaa
    13681 tgtaagaaac tgtcacgaaa ttaaaatgaa gttcttacat aagcgaacca taaaaaattt
    13741 cattttgatt ttaaaacagt tcaagaaagt caaaaaatta ttctatttga aagagaggtg
    13801 ccgactgtga aagtcaataa aatccgtatg cgggaaacag tgatttccta cgctttccta
    13861 gcaccagtat tattcttctt tgtcatcttt gtgttggctc cgatggtgat gggcttcatt
    13921 acaagtttct ttaactactc aatgactaaa tttgagtttg tgggcttaga taactatatc
    13981 cgtatgttta aagatcctgt ctttacaaaa tctctgatta acacagttat tttggttatt
    14041 ggatctgtac cagttgttgt tctattctca ctctttgtag catctcagac ctatcatcaa
    14101 aatgtcattg ccagatcctt ctaccgtttc gtcttcttcc ttcctgttgt aacgggtagt
    14161 gttgccgtga cagttgtttg gaaatggatt tatgacccac tatcagggat tctaaacttt
    14221 gtccttaagt caagccacat catcagccaa aacatttctt ggttgggaga taaaaactgg
    14281 gcattgatgg cgattatgat tattctcttg accacttcag ttggtcagcc catcatcctt
    14341 tatatcgctg ccatggggaa tattgacaat tcactggttg aagcggcgcg tgttgatggt
    14401 gcaactgagt ttcaagtttt ttggaagatt aaatggccaa gccttcttcc aacaactctt
    14461 tatattgcaa tcatcacaac aattaactca ttccagtgtt tcgccttgat tcagcttttg
    14521 acatctggtg gtccaaacta ctcaacaagt accttgatgt actaccttta cgaaaaagcc
    14581 ttccaattga cagaatacgg ctatgccaac acaattggtg tcttcttggc agtcatgatt
    14641 gctatcgtaa gctttgttca atttaaagta cttggaaacg acgtagaata ctaaagaaag
    14701 gagacagcta tgcaatctac agaaaaaaaa ccattaacag cctttactgt tatttcaaca
    14761 atcattttgc tcttgttgac tgtgctgttc atctttccat tctactggat tttgacaggg
    14821 gcattcaaat cacaacctga tacaattgtt attcctcctc agtggttccc taaaatgcca
    14881 accatggaaa acttccaaca actcatggtg cagaaccctg ccttgcaatg gatgtggaac
    14941 tcagtattta tctcattggt aaccatgttc ttagtttgtg caacctcatc tctagcaggt
    15001 tatgtattgg ctaaaaaacg tttctatggt caacgcattc tatttgctat ctttatcgct
    15061 gctatggcgc ttccaaaaca agttgtcctt gtaccattgg tacgtatcgt caacttcatg
    15121 ggaatccacg atactctctg ggcagttatc ttgcctttga ttggatggcc attcggtgtc
    15181 ttcctcatga aacaatttag tgaaaatatt cctacagagt tgcttgaatc agctaaaatc
    15241 gacggttgtg gtgagattcg taccttctgg agtgtagcct tcccgattgt gaaaccaggg
    15301 tttgcagccc ttgcaatctt taccttcatc aatacttgga atgactactt catgcaattg
    15361 gtaatgttga cttcacgtaa caatttgacc atctcacttg gggttgcgac catgcaggct
    15421 gaaatggcaa ccaactatgg tttgattatg gcaggagctg cccttgctgc tgttccaatc
    15481 gtcacagtct tcctagtctt ccaaaaatcc ttcacacagg gtattactat gggagcggtc
    15541 aaaggataat actctgagaa aatctcttca aactacgtca gcgtcacctt gccatactta
    15601 agtattgcct gcggttagct tcctagtttg ttcttcaatt ttcattgagt ataggaaaat
    15661 caatctatca agatacagaa gtatatttta tagatttaga gaatatagag gttataagtg
    15721 tctacaaaat ggagggtatg cagttacttt atgaagtttt gtcagacact tataaactta
    15781 agaatggttt tagttaacta tcagaaacga aggaaagagt atgatttttg acgatttgaa
    15841 aaacatcacc ttttacaaag ggattcatcc caatttagac aaggctatcg actatctcta
    15901 ccaacatcgt aaagattcat tcgaattagg aaagtatgag attgatggag ataaagtctt
    15961 tctagttgtt caggaaaatg tcctcaatca agttgagaat aatcaatttg aacaccataa
    16021 gaactatgca gatttgcatt tgctggtaga aggacatgaa tattcgagct acggttcacg
    16081 tatcaaagac gaggcagtag cattcgacga agcgactgac attggctttg ttcattgtca
    16141 tgaacactac ccactcttgt tgggttatca taattttgcg attttcttcc caggtgagcc
    16201 acatcagcca actggctatg caggtatgga agaaaaggtt cgaaaatatc tctttaaaat
    16261 tttgattgat taaaaatagg atgaattgtt tttttgtaaa gctttgacaa tactctacca
    16321 tgaaattgat ctttgtgagg tagagaaatg agaataaaat atttaaaaat tggtatcttc
    16381 taagcatgct gcaagagcta gtttcttaga tggacagggg attacagttg atgagatgtc
    16441 ctggataatt aatggcattg tgaatgcatt gattggtaga tacataaaat taggtactta
    16501 tgcagctaag tatggtatta gtatagcacg ctcgatctta agtagggcag ctgcaactgc
    16561 agcagcaaga gtaggattac tgaccaagat ttctggatgg attttacgag tagctgtgaa
    16621 tgtagctgat gtatatggta attttgccaa caatattgct gcagcttggg atgcatatga
    16681 taaaattcct aacaatggtc gtataaactt ttaaaatgcg agaatgaaag cactttgtat
    16741 ttttttattg aatatgttag cttggacagt gcttgcaatg ataattcgtg gagggctaga
    16801 tggatttgat aggcatactt ggagtactat tttaattgct tcgctgttcg gggtatatga
    16861 ttataagccc atagataaaa atagaaaaaa gtccaaaaga aaaaagaaaa aatagatttg
    16921 ttcatggtag ggacttatga aagctttact gacaaaaaag aaaacagttt acaaagaaaa
    16981 atgatggagg agcaaacatg gcacaaaaag gagtaagcct tatcaaggca gcatttgata
    17041 cagataactt tctcatgcgt tttagtgaga aggtcttgga catcgtgaca gccaatcttc
    17101 tttttgtcgt ctcttgtttg cccatcgtga cgattggagt ggctaaaatc agcctctacg
    17161 agaccatgtt cgaagttaag aagagcagac gggtgcctgt ttttaaaatc tatctaagat
    17221 ctttcaagca aaatctgaaa ctaggtcttc agttaggtct gcttgagttg ggcattgttt
    17281 cattaagcct cctagatctt tatctctttt ggggtcaaac agctctgccc tttcaattgc
    17341 tgaaagctat ttgtctaggc attctgattt tccttacgat tgtgatgttg gctagctatc
    17401 caatcgcggc acgttatgat ttaacttgga aagaaattct tcaaaaagga ttgatgttgg
    17461 ctagttttaa ctttccttgg ttcttcctca tgttagccat tcttgtcctc attgtgatgg
    17521 ttctttatct gtctgccttc agtctactct taggtggctc agtcttcctg ctttttgggt
    17581 ttggactatt ggtctttatc cagactggat tgatggagaa aattttcgca aaataccaat
    17641 aggagcctta tttctgaaac tactttcaaa ggctccaaac gctattctat aagcgagaaa
    17701 ctaaaatcta agtgtctata agatattgaa agccttttcg gtaaagtgta tactaaagaa
    17761 gtaaagaaaa atctgcttta gcagaaaata aaaataatag gagaaaatct atgtcagatt
    17821 tgaaaaaata cgaaggtgtc attccagcct tctacgcatg ttatgatgag caaggagaag
    17881 taagtccaga gcgtacgcgt gccttggttc aatacttcat tgataaaggt gttcaaggtc
    17941 tttatgtcaa tggttcttct ggtgaatgta tctaccaaag cgttgaagat cgcaagttga
    18001 ttttggaaga agtcatggcg gtagccaaag gtaaattgac cattattgcc catgttgctt
    18061 gcaataatac taaagatagt atggaacttg ctcgccatgc tgaaagcttg ggagtagatg
    18121 ctattgcaac gattccacca atttacttcc gcttgccaga atactcagtt gccaaatact
    18181 ggaacgatat tagttctgca gctccaaaca cagactacgt gatttacaac attcctcaat
    18241 tggcaggggt tgctttgact ccaagccttt acacagaaat gttgaaaaat cctcgtgtta
    18301 tcggtgttaa gaactcttct atgccagttc aagatatcca aacctttgtc agccttggcg
    18361 gggaagacca tattgtcttt aacggtccag atgaacagtt cctaggtggc cgcctcatgg
    18421 gtgctaaggc tggtatcggt ggtacttatg gtgctatgcc agaactcttc ttgaaactca
    18481 atcagttgat tgcggataag gacctagaaa cagcgcgtga attgcagtat gctatcaacg
    18541 caatcattgg taaactcact tctgctcatg gaaatatgta cggtgtcatc aaagaagtct
    18601 tgaaaatcaa tgaaggcttg aatattggat ctgttcgttc accattgaca ccagtaactg
    18661 aagaagatcg tccagttgta gaagcggctg cagccttgat tcgtgaaacc aaggagcgct
    18721 tcctctaatc taaaaggagg tatttatgac atactacgtt gcaattgata tcggtggaac
    18781 taacatcaag tatggtttgg ttgatcaaga ggggcaactt cttgaatcgc atgaaatgcc
    18841 aactgaggcg cataagggtg gacctcatat cttacaaaag accaaagata tcgtagctag
    18901 ttatttagaa aaaggcccag tagcaggtgt tgccatatct tctgctggga tggtggatcc
    18961 ggataagggt gagattttct atgctgggcc gcaaatccct aactacgcag gcacccagtt
    19021 caaaaaggaa atcgaagaaa gctttactat tccttgtgag attgaaaatg atgtcaactg
    19081 tgcaggtctt gctgaggcag tatctggttc aggcaaggga gcaagtgtga cactttgctt
    19141 gaccattgga acaggtatcg gtggttgctt gattatggat aggaaagtct tccatggttt
    19201 tagtaattca gcctgtgaag tcgggtatat gcatatgcag gatggagctt ttcaagactt
    19261 ggcttctaca acagctttag tgaaatatgt agctgaagcc catggagaag atgttgatca
    19321 gtggaatggc cgacgtatct ttaaggaagc tactgaagga aacaaaatct gcatggaagg
    19381 tattgaccgt atggttgact atctaggaaa aggtctggca aatatttgct acgttgccaa
    19441 tccagaagtg gttattcttg gtggtggtat catggggcaa gaggctatcc tcaaacctaa
    19501 gatccgcaca gccttgaaag aggctttggt accaagttta gcagaaaaaa cacgattaga
    19561 atttgcccat caccaaaata cagcagggat gttgggtgca tattatcatt ttaagacaaa
    19621 acaatcctag tttggctcag ccaaactagg attttcttac acgtttttgt ctacgatagc
    19681 cgttgagttt tttattttcc cagtagctat taaagatttt ttccttgctt tcgcgattga
    19741 tttccaaaaa gtaggcataa atcaaatcga taaagaagag cataggaagt tgagcggata
    19801 ttcgttggat ataggagggt tggctgtggg tggctacaag aacagtctct gtataggtct
    19861 ggctatcttt attgggaaca cttgtaaaga gtacagtctt tgcccccatc tccttggcat
    19921 ctaatagact atctaaaata gaaggagttg agcctgaaag tgagaagccc agtactagac
    19981 aattttcatc catgatgctg gttgtccagg caaagccgtc ttggtctgtc aaagcttcgc
    20041 agaccacacc tagtcgcata aaacgtaatt tcatttcacg ggcgacgagg ccagaactcc
    20101 ctgttccgaa gaagtagata cgctcagcat cttcgattag ctgggcaatt cgttctagtt
    20161 ggatttcgtc aatcaagtct tgtgtttgtt ccctcatgtt gctataactt ctgaggactc
    20221 gtttggtcag tggactgtgc ttggagactt ggttggcttg attttctgcc tgatgttggt
    20281 attggaaaat aaattctcgg tagccagtaa agccacactt tttagcaaag cgggtcaaag
    20341 cagcttgaga aatatgtaat ttttgggtga cttgttgaga agataaatca tctgtaatcg
    20401 tttcagcttg caaaaaatag cgagcgattt cttgttctag gtctgtcatt tcttcaaaat
    20461 gtgaatcaat gatagttgcg atatctggtt tgtccatagg gaaagctcct ttacatgagt
    20521 catactggaa gactagatca gggaatagtc acacttcatt ataacacata atataaggat
    20581 agataaataa aaacgcatct ctgttttaaa aacgaaaaaa tcgaaaaagc ttctctcttt
    20641 tccataattt tctactcaaa ttgtggtaca attaagagta agattttaag ttagaaatga
    20701 gactgatttg tatgagaaaa tttaacagcc attcgattcc gattcggctt aatttattgt
    20761 tttcaatcgt cattttactc tttatgacca ttattggtcg tttgttgtat atgcaggttt
    20821 tgaacaagga tttttacgaa aaaaagctag cctcagctag tcagaccaag attacaagca
    20881 gttcagcccg tggggaaatt tatgatgcta gtggaaaacc tttggtagaa aatacgttaa
    20941 agcaggttgt ttcctttacg cgtagcaata aaatgacagc tacagactta aaagaaacag
    21001 ctaaaaagtt actgacttat gtgagcatca gttctccaaa tttgacagaa cgccagctgg
    21061 cggattacta tttggctgat cctgaaatct ataaaaaaac agtggaagct ctcccaagcg
    21121 agaaacgctt ggattcagat ggcaatcgtc tatccgaatc agaactgtat aacaatgcgg
    21181 tcgatagtgt acaaacgagt caactaaact atacagagga tgaaaagaaa gaaatctatc
    21241 tttttagtca gttaaatgct gttggaaact ttgcgacagg aaccattgcg acagatcctc
    21301 taaatgattc tcaggtggct gttattgcct ctatttcaaa ggagatgcct ggcattagta
    21361 tttctacttc ttgggataga aaggttttgg aaacttccct ttcttctata gttgggagtg
    21421 tatccagtga aaaagctggt ctcccagcgg aagaagcaga agcctatctt aaaaaaggct
    21481 attctctaaa tgatcgtgta ggaacctcct atttggaaaa gcaatatgaa gagaccttac
    21541 aaggaaaacg ctcggtaaaa gaaatccatc tggataaata tggcaatatg gaaagcgtgg
    21601 atacaattga ggaaggtagt aagggaaaca atatcaaact gaccattgat ttggctttcc
    21661 aagatagcgt ggatgcttta ctgaaaagtt atttcaattc cgagctagaa aatggtggag
    21721 ccaagtattc tgaaggtgtc tatgcagtcg cccttaaccc aaaaacaggt gcggttttgt
    21781 ctatgtcagg gattaaacat gacttgaaaa cgggagagtt gacgcctgat tccttgggaa
    21841 cggtaaccaa tgtctttgtt ccaggttcgg ttgtcaaggc ggcgaccatc agctcaggtt
    21901 gggaaaatgg agtcttgtca ggaaaccaga ccttgacaga ccagtccatt gtcttccaag
    21961 gttcagctcc catcaattct tggtatactc aggcttacgg ttcattccct atcacagcgg
    22021 tccaagctct ggagtattca tcaaatacct atatggtcca aacagcctta ggtcttatgg
    22081 ggcaaaccta tcaacccaat atgtttgtcg gcaccagcaa tctagagtct gctatggaga
    22141 aactgcgttc aacctttggc gaatatggct tgggtactgc gacaggaatt gacctaccag
    22201 atgaatctac tggatttgtt cccaaagagt atagctttgc taattacatt actaatgcct
    22261 ttgggcagtt tgataactat acgccgatgc agttggctca gtatgtagca actattgcaa
    22321 ataatggtgt tcgtgtggct cctcgtattg ttgaaggcat ttatggtaat aatgataagg
    22381 gaggactggg tgacttgatt cagcaactgc aaccgacaga gatgaataag gtcaatatat
    22441 ccgactccga tatgagcatc ttgcaccaag gtttttatca ggttgcccat ggtactagtg
    22501 gattgacaac tggacgtgcc ttttcaaatg gtgccttggt atccattagc ggaaaaacag
    22561 gtacagccga aagctatgtg gcagatggtc agcaagcaac caataccaat gcggtggcct
    22621 atgccccatc tgataatccc caaatcgctg tcgcagtggt ctttcctcat aataccaatc
    22681 taacaaatgg tgtaggacct tccattgcgc gtgacattat caatctgtat caaaaatacc
    22741 atccaatgaa ctagaaagga aattatgctt tatccaacac ctattgccaa gttgattgac
    22801 agttattcta agttaccagg tatcgggatt aagacggcta cgcgtctggc cttttatacg
    22861 attgggatgt ctgctgatga tgtcaatgaa tttgcaaaaa atctcctttc tgctaagaga
    22921 gaattgacat attgttctat ttgtggacgt ttgacagacg acgatccttg ttctatctgt
    22981 actgattcga ctcgtgacca gacaacaatt ttagttcttg aggatagtag agatgtggca
    23041 gccatggaaa atatccaaga ataccatgga ctctatcatg tcctgcatgg cctcatttct
    23101 cctatgaatg gtatcagtcc ggacgatatc aatcttaaga gccttatgac tcgtcttatg
    23161 gatagtgagg tttcagaagt gattgtggcg actaatgcta cagcggatgg tgaagcgacc
    23221 tccatgtatc tttcacgttt gctcaagccg gctggtatca aggttacgcg tctagcacga
    23281 ggtctcgctg tgggagcgga cattgagtat gcggacgaag tgacactctt acgagcgatt
    23341 gaaaatcgga cagagttgta agtgtaggca aatttacgaa ctccattcat ttataaaaaa
    23401 tcaaagaggc tgaaaatcgt tcctatcggc ctctttttgt atagtgtgat gagtagaatc
    23461 aggttcaagt tttaaaaaac caagcaaata tgatatacta aagagcgagt attctagtag
    23521 aattaggaca aataatatga aacaaacgat tattctttta tatggtggac ggagtgcgga
    23581 acgcgaagtc tctgtccttt cagctgagag tgtcatgcgt gcggtcaatt acgaccgttt
    23641 cacagtcaag actttcttta tcagtcagtc aggtgactct atcaaaacgc aggaatttag
    23701 tcatgctccg gggcaagaag accgtctcat gaccaatgaa accattgatt gggataagaa
    23761 agttgcacca agtgctatct acgaagaagg tgcagtggtc tttccagtcc ttcacgggcc
    23821 aatgggagaa gatggctctg ttcaaggatt cttggaagtt ttgaaaatgc cttacgttgg
    23881 ttgcaacatt ttgtcatcaa gtcttgccat ggataaaatc acgactaagc gtgttctgga
    23941 atctgctggt attgcccaag ttccttatgt ggctatcgtt gaaggcgatg atgtgactgc
    24001 taaaatagct gaagtggaag aaaaattggc ttatccagtc ttcactaagc cgtcaaacat
    24061 ggggtctagt gtcggtattt ctaagtctga aaaccaagaa gaactccgtc aagccttaaa
    24121 acttgccttc cgatatgaca gccgtgtctt ggttgagcaa ggagtgaatg cccgtgaaat
    24181 tgaggttggc ctcttgggta actacgatgt caagagcacg ctacctggag aagttgtcaa
    24241 ggacgttgcc ttttatgact acgatgccaa gtatattgat aacaaggtta ctatggatat
    24301 tcctgccaaa atcagtgatg atgtggtggc tgtcatgcgt caaaatgcag aaacagcctt
    24361 ccgtgccatt ggtggccttg gtctatctcg ttgcgatttc ttctatacag ataagggaga
    24421 gatttttctc aacgagctca ataccatgcc aggtttcacc cagtggtcta tgtacccact
    24481 actttgggaa aatatgggga tcagctaccc agaactaatc gagcgtttgg ttgaccttgc
    24541 caaggaaagt tttgacaagc gcgaagcgca tttgatataa aatgaaagag agggtagaag
    24601 ccagaaccat cactgcaagg tgactagagt tctcggactt cagccctttt taaaggagta
    24661 gaaatgaaat taacaatcca tgaaattgcc caagttgttg gagccaaaaa tgatatcagt
    24721 atctttgagg acactcagtt agaaaaagct gagtttgata gtcgtttgat tggaactgga
    24781 gatttatttg tgccacttaa aggtgcgcgt gatggccatg actttattga aacagccttt
    24841 gaaaatggtg cagcagtaac cttgtctgag aaagaggtct caaatcatcc ttacatttta
    24901 gtagatgatg ttttgacagc ctttcaatcc ctagcatcct actatcttga aaaaacgact
    24961 gttgatgtct ttgctgttac aggttcaaat ggcaagacaa cgactaagga tatgttggcg
    25021 catttactgt caacaagata caagacctac aaaacacaag gcaattacaa taatgagatt
    25081 ggccttcctt acacagttct tcatatgcct gaaggaacag aaaagttggt tttggagatg
    25141 ggacaggatc acttgggaga tattcatctc ttgtctgaat tggctcgtcc aaaaacagcc
    25201 atcgtgacct tggttggaga agctcatttg gcctttttca aagatcgttc tgagattgct
    25261 aaaggaaaaa tgcaaattgc agacggaatg gcttcaggtt ccttgctttt agcgccggct
    25321 gaccctatcg tagaggacta tttgccaatt gataaaaagg tggttcgttt tggtcaagga
    25381 gcagagctgg aaattactga cttggttgag cgtaaggaca gtctgacctt taaggctaat
    25441 ttcttggaac aagcccttga tttgccagta actggcaagt acaatgcgac aaatgctatg
    25501 attgcatcct atgttgcctt gcaagaagga gtttcagagg agcaaattcg tttggcattc
    25561 caacatcttg aattgacgcg taaccgtacc gagtggaaga aagcagccaa tggagcagat
    25621 atcctgtcag atgtttacaa tgccaatcca actgctatga aactgatttt agagactttc
    25681 tctgccattc cagccaatga aggtggcaag aaaattgcag tgttggcgga tatgaaggag
    25741 cttggtgacc agtctgttca acttcataat cagatgattt tgagcctctc cccagatgtg
    25801 cttgatatcg ttattttcta tggagaagat attgctcagt tggctcaatt ggccagtcaa
    25861 atgtttccaa tcggccacgt ttactacttc aagaaaacag aagaccagga tcaatttgaa
    25921 gacctagtca agcaggttaa ggaaagcctt ggagcctatg accaaatctt gctaaaaggt
    25981 tctaactcta tgaatctagc caaattggta gaaagtttag aaaatgaatg caagtgattt
    26041 tgctaagtat cttcaaagaa tgattgctct tacagatact ggactaacct ttacaaagga
    26101 tccgtttgac cgtgagcgct acgaagactt gcgaagtctg ttatctgaaa tgttgaatca
    26161 ggtatcagac cttgatgcag acgaagtggc agaactcttg aaaccgacct ccgcttatgc
    26221 gactccttta atggacgtcc gtgcttggat agttgaggat gaaaaaattt gtctggttag
    26281 gggacaagga gagaatgatt gggctttgcc aggtggcttt ggcgaggtcg gttattcacc
    26341 aactgaaaat attctcaagg aaattgaaga agaaaccggt tttaaagcca aagttgaacg
    26401 actactagct gtttttgata ccaatcgttt ccaactacag agcaaacaat atgcaaagtt
    26461 tgtttttgaa tgtaagcttc tcgatggaca atttcaagaa aatcaagaaa tcgctgacct
    26521 tcaatttttt gcaattgacc aactgccgaa tttatctgaa aaacgcatta ccaaggagca
    26581 aatagagctt ctttggcagg tttatcaagg tcataggggg caatatcttg actaagaaga
    26641 tgattatcgt atttctaaat ccatttttaa caactagcat ggtataataa tatgcaggaa
    26701 aattttgaat tatgaggaag actagatgaa tttatgggat attttcttta cgactcaggc
    26761 aaccgagccg cccaaatttg accttttttg gtatgttagc ctatttacgc tcttagcctt
    26821 aaccttttat acagcccatc gctatcgtga aaataaggtt taccaacgat ttttccaaat
    26881 cttgcagact gttcagttaa tccttcttta tggttggtac tgggtcaatc atatgccact
    26941 gtcagaaagc ctaccctttt accattgccg tatggctatg tttgtggtac tcttgcttcc
    27001 tggtcaatcc aaatataaac aatactttgc attattggga acatttggga cattagcagc
    27061 ctttgtttat ccagtgccag atgcttaccc ttttccacat atcaccattc tatcctttat
    27121 ctttggtcat ttagcactct tggggaactc tctagtttat ctattgagac agtataatgc
    27181 gcgattgctg gatgtgaagg gaatttttct catgaccttt gccctaaatg ccttgatttt
    27241 tgtggtcaat ttggtgacag gtggcgatta cggatttttg acaaaaccgc cattggttgg
    27301 ggatcacggt ctagtagcta attatttact tgtttcaatt gtgctggtag ctactatcag
    27361 tttgactaag aaaatcttag aattcttttt agctcaagaa gcagaaaaaa tgattgcaaa
    27421 ggaagcttaa cacagagctt tcttttttgc tcttagagag tttttacaag cagcttataa
    27481 aataagaatt tctgaataga caaactcaaa aaatggctgg gaaatttagg aaaaaagcaa
    27541 gcacgattaa attttttgtg ttataatact ttgtgaatag ctatgcctat gtttagctat
    27601 ggaataatac gaagtgcgaa acttggaaga tagagaggaa gcgatgtaat ggctagagaa
    27661 ggctttttta caggtctaga tattggaaca agctctgtca aggtgcttgt ggccgagcag
    27721 agaaatggtg aattaaatgt aattggcgtg agtaatgcca aaagtaaagg tgtaaaggat
    27781 ggaattattg ttgatattga tgcagcagca actgctatca agtcagccat ttcccaagcg
    27841 gaagaaaagg caggcatttc gattaaatca gtgaatgtcg gcttgcctgg taatcttttg
    27901 caggtagaac caactcaggg gatgattcca gtaacatctg atactaagga aattacggat
    27961 caagatgttg aaaatgttgt caaatcagct ttgacaaaga gtatgacacc tgaccgtgaa
    28021 gtcattacct ttattcctga agaatttatt gtggatggtt tccaagggat tcgtgaccca
    28081 cgtggcatga tgggggttcg ccttgaaatg cgtggtttgc tttatacagg acctcgtact
    28141 atcttgcaca atttgcgtaa gacggttgag cgtgcaggtg ttcaggttga aaatgttatc
    28201 atttcaccac tagcaatggt tcagtctgtt ttgaacgaag gggaacgtga atttggtgct
    28261 acagtgattg atatgggggc aggtcaaacg actgtcgcta caatccgtaa tcaagaactc
    28321 cagttcacac atattctcca agaaggtgga gattatgtaa ctaaagatat ctccaaggtt
    28381 ttgaaaacct ctcgcaaatt agcggaaggc ttgaaactga attacgggga agcctatccg
    28441 cctcttgcaa gcaaagaaac cttccaagta gaggttattg gagaagtaga agcagtcgaa
    28501 gtgacggaag cctacttgtc agaaattatt tctgcacgaa tcaagcacat ccttgaacaa
    28561 atcaagcaag aattagatag aaggcgtcta ttggacctcc ctggtggtat tgtcttaatc
    28621 ggtgggaatg ccattttacc aggtatggtt gagcttgctc aggaagtctt tggcgtccgt
    28681 gtcaagcttt atgtcccaaa tcaagttggt atccgtaatc cagcctttgc gcatgtgatt
    28741 agtttatcag aatttgcggg tcaattaaca gaagttaatc ttttggctca gggagcgata
    28801 aaaggtgaga atgacttaag tcatcagcca attagttttg gtgggatgct gcaaaaaaca
    28861 gctcagtttg tacaatcaac gcctgttcaa ccagctcctg ctccagaagt agagccggtg
    28921 gcgcctacag aaccaatggc ggatttccaa caagcttcac aaaataaacc gaaattagca
    28981 gatcgtttcc gtggcttgat cggaagcatg tttgacgaat aaagaggaaa aataaattat
    29041 gacattttca tttgatacag ctgctgctca aggggcagtg attaaagtaa ttggtgtcgg
    29101 tggaggtggt ggcaatgcca tcaaccgtat ggtcgacgaa ggtgttacag gcgtagaatt
    29161 tatcgcagca aacacagatg tacaagcatt gagtagtaca aaagctgaga ctgttattca
    29221 gttgggacct aaattgactc gtggtttggg tgcaggaggt caacctgagg ttggtcgtaa
    29281 agccgctgaa gaaagcgaag aaacactgac ggaagctatt agtggtgccg atatggtctt
    29341 catcactgct ggtatgggag gaggctctgg aactggagct gctcctgtta ttgctcgtat
    29401 cgccaaagat ttaggtgcgc ttacagttgg tgttgtaaca cgtccctttg gttttgaagg
    29461 aagtaagcgt ggacaatttg ctgtagaagg aatcaatcaa cttcgtgagc atgtagacac
    29521 tctattgatt atctcaaaca acaatttgct tgaaattgtt gataagaaaa caccgctttt
    29581 ggaggctctt agcgaagcgg ataacgttct tcgtcaaggt gttcaaggga ttaccgattt
    29641 gattaccaat ccaggattga ttaaccttga ctttgccgat gtgaaaacgg taatggcaaa
    29701 caaagggaat gctcttatgg gtattggtat cggtagtgga gaagaacgtg tggtagaagc
    29761 ggcacgtaag gcaatctatt caccacttct tgaaacaact attgacggtg ctgaggatgt
    29821 tatcgtcaac gttactggtg gtcttgactt aaccttgatt gaggcagaag aggcttcaca
    29881 aattgtgaac caggcagcag gtcaaggagt gaacatctgg ctcggtactt caattgatga
    29941 aagtatgcgt gatgaaattc gtgtaacagt tgttgcaacg ggtgttcgtc aagaccgcgt
    30001 agaaaaggtt gtggctccac aagctagaac tgctactaac taccgtgaga cagtgaaacc
    30061 agctcattca catggctttg atcgtcattt tgatatggca gaaacagttg aattgccaaa
    30121 acaaaatcca cgtcgtttgg aaccaactca ggcatctgct tttggtgatt gggatcttcg
    30181 ccgtgaatcg attgttcgta caacagattc agtcgtttct ccagtcgagc gctttgaagc
    30241 cccaatttca caagatgaag atgaattgga tacacctcca tttttcaaaa atcgttaagt
    30301 aaatgaatgt aaaagaaaat acagaacttg tttttcgaga agttgcagag gctagtctga
    30361 gtgctaatcg agagagtggt tcggtctctg tcattgcagt taccaagtat gtagatgtac
    30421 cgacagcgga agccttgctt ccgctaggtg ttcatcatat cggtgaaaat cgtgtagata
    30481 agtttctgga aaaatatgaa gctttaaaag atcgagatgt gacttggcat ttgattggta
    30541 ccttgcaaag acgtaaggtg aaagatgtca ttcaatacgt tgattatttc catgcattgg
    30601 actcagtaaa gctagcaggg gaaattcaaa aaagaagtga ccgagtcatc aagtgtttcc
    30661 ttcaagtaaa tatttctaaa gaagaaagca aacacggttt ttcgagagag gaactgctgg
    30721 aaatcttgcc agagttagcc agactagata agattgaata tgttggttta atgacgatgg
    30781 caccttttga ggctagcagt gagcagttga aagagatttt caaggcgacc caagatttac
    30841 aaagagaaat tcaagagaaa caaattccaa atatgcctat gaccgagtta agtatgggaa
    30901 tgagtcgtga ttataaagaa gcgattcaat tcggttccac ttttgttcgt ataggtacat
    30961 cattttttaa gtaggagaga accatgtctt taaaagatag attcgataga tttatagatt
    31021 attttacgga ggatgaggat tcaagtctcc cttatgaaaa aagagatgag cctgtgttta
    31081 ctccagtaaa ttcttcacag gaaccggctc tcccaatgaa tcaaccttca cagtcggctg
    31141 gtacaaaaga gaacaatatc accagacttc atgcaagaca acaggaattg gcaaatcaga
    31201 gtcagcgtgc aacggataag gtcattatag atgttcgtta tcctagaaaa tatgaggatg
    31261 caacagaaat tgttgattta ttggcaggaa acgaaagtat cttgattgat tttcagtata
    31321 tgacagaggt gcaggctcgt cgttgtttgg actatttgga tggagcttgt catgttttag
    31381 ctggaaattt gaaaaaggta gcttctacca tgtatttgtt gacaccagtg aatgttattg
    31441 taaatgttga agatatccgt ttaccagatg aagatcaaca gggtgagttc ggttttgata
    31501 tgaagcgaaa tagagtacga taatgatttt tttaattcgt atgatttata atgcagtgga
    31561 tatttactcc ctgattttgg tagccttcgc tgtcatgtct tggtttccag gtgcctacga
    31621 atccagttta ggtcgttgga ttgtagcgtt ggtgaaacca gtacttgctc ccttgcaacg
    31681 cctgccttta cagatagcgg gtcttgattt atctgtttgg gtcgcgattg ttttggttcg
    31741 atttttagga gaaaacctag tgcgttttct ggcgatgata ggatgaataa agggatttat
    31801 cagcatttct ccatagaaga tcgtccattt cttgacaagg gaatggaatg gataaagaag
    31861 gtagaagata gctatgctcc ttttttaact ccttttatca atcctcatca ggagaagcta
    31921 ttaaagattt tggccaaaac ctatggtctt gcttgtagca gtagtgggga attcgtctcg
    31981 agtgagtatg ttcgagtttt attataccca gattatttcc aaccagagtt ttcagatttt
    32041 gaaatatctc tccaagaaat tgtgtattcc aataaatttg aacatttaac gcatgctaag
    32101 attttaggga cagtcatcaa tcaattaggg attgaacgga aactttttgg agatatccta
    32161 gtagatgaag aacgggcgca gattatgatt aatcagcagt ttcttcttct ctttcaagat
    32221 ggactaaaga aaattggtcg tatacctgtt tcgctggagg aacgtccttt caccgagaaa
    32281 atagataagc tagaacagta tcgagaactg aatttatctg tgtctagttt tcgattagat
    32341 gttcttttat caaatgtttt gaaactatct aggaatcaag caaaccagtt gattgaaaag
    32401 aaacttgtcc aagtaaatta tcatgtggta gacaaatcag attacactgt tcaagttgga
    32461 gacttgatta gtgtgagaaa atttggtcgc ttgagattat ttcaagataa gggacaaacg
    32521 aaaaaagaga agaaaaaaat aaccgtccag ttattattaa gtaagtgagg aatagaatgc
    32581 caattacatc attagaaata aaggacaaga cctttggaac tcgattcaga ggttttgatc
    32641 cagaagaagt cgatgaattt ttagatattg tggttcgtga ttacgaagat cttgtgcgtg
    32701 cgaatcatga taaaaatttg cgtattaaga gtttagaaga gcgtttgtct tactttgatg
    32761 aaataaaaga ttcattgagc cagtctgtat tgattgccca ggatacagct gagagagtga
    32821 aacaggcggc gcatgaacgt tcaaacaata tcattcatca agcagagcaa gatgcgcaac
    32881 gcttgttgga agaagctaaa tataaggcaa acgagattct tcgtcaagca actgataatg
    32941 ctaagaaagt cgctgttgaa acagaagaat tgaagaacaa gagccgtgtc ttccaccaac
    33001 gtctcaaatc tacaattgag agtcagttgg ctattgttga atcttcagat tgggaagata
    33061 ttctccgtcc aacagctact tatcttcaaa ctagtgatga agcctttaaa gaagtggtta
    33121 gcgaagtact tggagaaccg attccagctc caattgaaga agaaccaatt gatatgacac
    33181 gtcagttctc tcaagcagaa atggaagaat tacaagctcg tattgaggta gccgataaag
    33241 aattgtctga atttgaagct cagattaaac aggaagtgga aactccaact cctgtagtga
    33301 gtcctcaagt tgaagaagag cctctgctca tccagttggc ccaatgtatg aagaaccaga
    33361 agtagctcca gtgcatccga caggtccaac accagctaca gaaactgttg attcagcacc
    33421 aggatttgaa gcaccgcaag aatccgttac aattttataa gaaacgatgt gagaacaata
    33481 tcttatcctt atatttccag cgagcaggag atggtgtgag tcctgcattc cctaacgata
    33541 agattatcct ctcaaaaact caagtctgaa gctagtaaga tttgacgttt cccacgttac
    33601 gggataagag ggagaaagac taaatctttt tccgaataaa ggtggtacca cgattttcgt
    33661 cctttttgga agtcgtggtt tttaatttgt tattatttat aaaggagata ccatgaaact
    33721 caaagatacc cttaatcttg ggaaaacagc tttcccaatg cgtgcaggcc ttccgaccaa
    33781 agagccagtt tggcaaaagg aatgggaaga tgcaaaactt taccaacgtc gtcaagaact
    33841 aaatgaaggg aaaccgcatt ttgtcttgca tgatggccct ccatacgcaa acggaaatat
    33901 ccacgttgga catgccatga atcatatctc aaaagatatc atcattcgtt ctaagtctat
    33961 gtcaggtttt aacgcacctt atatcccagg ttgggatact catggtctgc caatcgagca
    34021 agttttggca aagcaaggtg tgaagcgcaa agaaatggac ttggttgagt acttgaaact
    34081 ctgtcgtgag tacgctcttt ctcaagttta taaacaacgt gatgatttca aacgcttggg
    34141 gatgtcaggt gactgggaaa atttatatgt gactttaact ccagactatg aagcagccca
    34201 aatccgtgtc tttggtgaga tggctaataa gggttatatc taccgtggtg ccaagccagt
    34261 ttactggtca tggtcatctg agtcagccct tgccgaagcg gaaattgaat accatgattt
    34321 ggtttcgact tcactttatt atgccaataa ggtaaaagat ggcaaaggta tcctagatac
    34381 agatacttat atcgtagtct ggacaacaac tccatttacc atcacagctt ctcgtggttt
    34441 gactgttggt gcagatattg attacgtttt ggttcaacct gctagtgaaa ctcgtaagtt
    34501 tgtcgttgct gcagaattgt tgactagctt gtctgagaaa tttggctggg ctgatgttca
    34561 agtgttggca acttaccgtg gtcaagaact caaccacatc gtaacagaac acccatggga
    34621 tacagctgta gatgagttgg taatccttgg tgatcacgtt accactgact ctggtacagg
    34681 tatcgtccat acagcccctg gttttggtga ggacgactac aatgttggta ttgctaatgg
    34741 tcttgaagtc gcagtgactg ttgacgaacg cggtatcatg atggcgaatg ctggtcctga
    34801 gtttgaaggt cagttctacg acaaggttgt accaactgtt attgaaaaac ttggtaacct
    34861 ccttctagcc caagaagaaa tctctcactc atacccattt gactggcgta ctaagaaacc
    34921 aatcatctgg cgtgcagttc cacaatggtt tgcctcagtt tcaaaattcc gccaagaaat
    34981 cttggatgct attgataaag ttaaattcca tacagaatgg ggtaaagtac gtctatataa
    35041 tatgattcgt gaccgtggtg actgggttat ctctcgtcaa cgtgcttggg gtgttccact
    35101 tccaatcttc tatgcagaag acggtacagc tatcatgaca gctgagacta ttgaacatgt
    35161 ggcgcaactc tttgaagtac atggttcaag catttggtgg gaacgtgatg ccaaagacct
    35221 cttaccagaa ggatttacac atccaggttc tccaaatggg gagttcaaga aagaaacaga
    35281 tattatggat gtatggtttg actcaggttc atcatggaat ggtgttttgg taaatcgtcc
    35341 aaatctgact tatccagctg acctttacct tgaaggttct gaccaatacc gtggttggtt
    35401 caactcatca ctcattacat ctgttgccaa ccatggcgta gcaccttaca aacaaatctt
    35461 gtcacaaggt tttacccttg atggtaaagg tgagaagatg tctaaatcac ttggaaatac
    35521 cattgctcca agtgatgttg aaaaacaatt tggtgcagaa atcttgcgtc tctgggtaac
    35581 aagtgttgac tcaagcaatg acgtgcgtat ctctatggat attttgagcc aagtttctga
    35641 aacttaccgt aagattcgta acactcttcg tttcttgatt gccaatacat ctgactttaa
    35701 cccagctcaa gatgtagtcg cttacgatga acttcgttca gttgataagt acatgactat
    35761 tcgctttaac cagcttgtca agaccattcg tgatgcctat gcggactttg aattcttgac
    35821 aatctacaag gccttggtga actttatcaa cgttgacttg tcagccttct accttgattt
    35881 tgccaaagat gttgtttaca ttgaaggtgc caaatcattg gaacgccgtc aaatgcagac
    35941 tgttttctat gacattcttg tcaaaatcac caaactcttg acaccaatcc ttcctcacac
    36001 tgcggaagaa atctggtcat atcttgagtt tgaagctgaa gacttcgttc aattgtcaga
    36061 attgccagaa gctcaaactt ttgctaatca agaagaagtc ttggatacat gggcagcctt
    36121 catggacttc cgtggacaag ctcaaaaagc cttggaagaa gctcgtaatg caaaagttat
    36181 cgggaaatcg cttgaagcac acttgacagt ttatccaaat gaagttgtga aaactctact
    36241 cgaagcagta aacagcaatg tggctcaact tttgatcgtg tcagacttga ccatcgcaga
    36301 agggccagct ccagaagctg cccttagctt cgaagatgta gccttcacag ttgaacgcgc
    36361 tgcaggtcaa gtatgtgacc gttgccgtcg tatcgaccca acaacagcag aacgcagcta
    36421 ccaggcagtc atctgtgacc actgtgcaag catcgtagaa gaaaactttg cggaagcagt
    36481 cgcagaagga tttgaagaga aataaggttg aaaagtctag gcaaaattca atttgagaag
    36541 aaaagacaac taattttata gtctattaaa cgcattgtat cacgtttttg aatacctgat
    36601 atgatgcgtt ttttatttat tttaaaaatt tgcgaggtat gactttttat actcaacaag
    36661 aatcaaagag aaacttagca agctaacagt agtaagataa aataggaatt tgatattagg
    36721 gataagattg ctaaatagtg taatattttt acaataataa atttatatag ttatttttgg
    36781 tttctgaaaa gtattatatt ttatttcata ttatacaaat ttttatttta taatatcaga
    36841 aaatactttt tttaaaagca aatatgatac aattttattt gaaaaaaata aaaaaggaga
    36901 ttttattatg aaattaaaaa cacttgcttt aattagtggt atcgtcggtc ttgtgggagg
    36961 aattttactt cttattggtc cttttgtctt gttgggaaca gcggtaaaca cagttgctac
    37021 aactcttaat ggaggagcta ctgcaggggc tttttcaggt gttgccttac tcttgaatgc
    37081 cttgaagatt gcaaatcttg ttcttggtat cattgctatt gtttactata aaggagataa
    37141 tcgtgtaggt gcagctccgt ctgtactaat gattgttttt ggtggagtta gtctcattcc
    37201 attcttagga tgggttgggg ggattcttgt tattatcgga ggatctctat tccttgcaac
    37261 attgaagaaa ttcaaatcag aagaataaaa ggtattttag catgaaaaga acaaaaaagt
    37321 ttatcggtat aggagtagct ctattatctc tttttcttct agttgcatgt ggaacataaa
    37381 gttcaaagga tacttcaaca agtaatgatg agaagacagt agcaacatcc aatagttcaa
    37441 aagaaacaat cactttcgat acaccggttg taacagacga tgtgattgaa tcaatacgca
    37501 cttatgcaga ttatatagat ctttataaaa atatttttga tgattatttt actaaagctg
    37561 aggaaggttt caaaggcaca gctatggaaa ataatgactc gtttactaaa ctaaaagagt
    37621 caactcaaaa attattcgat gcgcagaaaa aaaggttaaa taatgaagat agaatagaaa
    37681 caactaaaaa caatgtgatt gccaaacatt gtcaaacagt cctttccttt ttggttttga
    37741 ctagcttttt tgtgaaaaat tgtgtaaaat agaatagata aacgagggga aacctcggaa
    37801 aatttaaagg agaatccatc taatggtaaa attggttttt gctcgccacg gtgagtctga
    37861 atggaacaaa gctaaccttt tcactggttg ggctgatgtt gatttgtctg aaaaaggtac
    37921 acaacaagcg attgacgctg gtaaattgat caaagaagct ggtatcaaat ttgaccaagc
    37981 ttacacttca gtattgaaac gtgctatcaa aacaactaac ttggctcttg aagcttctga
    38041 ccaattgtgg gttccagttg aaaaatcatg gcgcttgaac gaacgtcact acggtggttt
    38101 gactggtaaa aataaagctg aagctgctga acaatttggt gatgagcaag ttcacatctg
    38161 gcgtcgttca tacgatgtat tgcctccaaa tatggaccgt gatgatgagc actcagctca
    38221 cacagaccgt cgttatgctt cacttgacga ctcagtaatc ccagatgctg aaaacttgaa
    38281 agtgactttg gaacgtgctc ttccattctg ggaagataaa atcgctccag ctcttaaaga
    38341 tggtaaaaac gtattcgtag gagctcacgg taactcaatc cgtgcccttg taaaacacat
    38401 caaaggtttg tcagatgacg agatcatgga cgtggaaatc cctaacttcc caccattggt
    38461 attcgaattc gacgaaaaat tgaacgtcgt ttctgaatac taccttggaa aataaaaaat
    38521 tgtaagtcta gaattgattt ctaggctttt tatgttagta tggaagtatg ataaggaata
    38581 aaaaacaaga ttatgtactg gcctacaagc aaccagtttc aaccacttac atgggttggg
    38641 aagaagaagc tttaccgata ggcaatggtt ctttaggagc aaaagtattt ggccttatag
    38701 gggctgaacg gattcaattt aatgaaaaaa gtctctggtc tggaggtcca cttcctgata
    38761 gttcagatta tcagggtgga aatcttcagg atcagtatgt ttttttagct gagattcggc
    38821 aggctttgga gaagagagat tacaatctgg ctaaggaact ggctgagcag cacctaattg
    38881 ggccaaaaac gagtcaatat gggacctatc tgtcttttgg ggatattcac attgagttca
    38941 gccagcaagg tacgactttg tctcaggtga cggactatca gagacagctg aatattagta
    39001 aggcacttgt gacgacttct tatgtctata agggaacgcg atttgaacgt gaagcttttg
    39061 cgagttttcc agatgatctc ttggttcagc gttttactaa ggaaggggcg gaaactctag
    39121 attttactat agaactatcc ttgacctgtg atttggcttc tgatggaaag tatgagcagg
    39181 aaaaatctga ttacaaggag tgtaagttgg atattactga ttctcatatc ttgatgaagg
    39241 gaagagttaa ggataatgat ctgcggtttg ctagttatct agcttgggaa acggatggag
    39301 atattagagt ttggtcagat agggttcaga tatcaggagc cagttatgcc aatctcttct
    39361 tggccgctaa gacggatttt gcccaaaatc ctgctagcaa ttatcgcaag aaactagatt
    39421 tagagcaaca ggtgatagac ttggtggaca cagctaaaga aaagggctat acccaattga
    39481 aatcaaggca tatcgaggac taccaagcct tattccagcg tgttcaattg gatttggaag
    39541 ctaatgttga cgcattcact acagatgatt tgttaaaaaa ttataagcca caagaagggc
    39601 aggctttgga ggagctgttc ttccagtatg gacggtattt attgattagt tcgtccagag
    39661 actgcccaga tgctctacca gctaacctac agggagtctg gaatgcggtc gacaatcctc
    39721 cttggaattc ggactatcac ttaaatgtca atctgcagat gaattattgg ccagcctatg
    39781 ttaccaatct cctagaggcg gtctttccgg tcatcaacta tgtagatgat ttgcgtgtct
    39841 atggtcgtct agcggctgta aagtatgcag gaatcgtctc tcaaaaaggt gaggaaaatg
    39901 gttggttggt tcatactcaa gcgactccct ttggttggac ggcacctggt tgggattact
    39961 attggggttg gtcaccagct gccaatgcgt ggatgatgca aactgtttat gaagcctatt
    40021 cattttatag ggaccaagac tatctcaggg agaaaattta tcccatgttg agggaaacgg
    40081 ttcgtttttg gaatgccttt ttacataagg atcagcaggc gcagcgttgg gtgtcttctc
    40141 cgtcttattc cccagaacat gggccgattt cgattggcaa tacttatgac caatctctga
    40201 tttggcagtt atttcatgat tttattcagg ctgctcagga attgggactg gatgaggact
    40261 tgttgactga ggttaaggag aagtctgatt tactaaatcc tttgcaaatc actcaatctg
    40321 gtcgaatcag ggagtggtat gaggaggaag agcagtattt tcaaaatgag aaagtggagg
    40381 ccccgcatcg gcacgcttcc catctagtgg gactctatcc tggcaatctc tttagctaca
    40441 agggacaaga gtatattgaa gcggcacgtg ctagcctcaa tgatcgtgga gatggcggca
    40501 caggctggtc caaggctaat aagatcaatc tctgggcgcg tttgggagat ggcaatcgag
    40561 cccataaatt attggcagag cagttaaaaa catccacctt gccaaatctt tggtgtagcc
    40621 atcctccttt tcagatagat ggtaattttg gtgctactag tggcatggca gaaatgttac
    40681 tccagtctca tgcagcttat ctggtacctc tagctgccct acctgatgct tggtcaacag
    40741 gttctgtttc aggcttaatg gcacgtggac attttgaagt gagcatgagc tgggaagata
    40801 aaaaactctt acagttgacc attttatcaa ggagtggagg agatttgcga gtttcttatc
    40861 cagatattga gaagagtgtg attaaaatga atcaagaaaa aataaaagcg aaatgcatgg
    40921 ggaaagattg tatttcggtg gcaacagcag aaggtgatct tgttcaattt tatttttaag
    40981 aagatgttat aaggcagtaa tttgaaactt ccttttaata aggatttaag aatataggca
    41041 gtttccaact agttgaaaaa gcgttataat gataatagga agtaatactc aatgaaaatc
    41101 aaagagcaca aactaggaag ctagccgcag gttgctcaaa acagtgtttt gaggttgtag
    41161 atggaagctg acgtggtttg aagagagatt ttcgaggagt ataatttgtt tgatagaggg
    41221 tgggtctgat ggcttatatt gatatgaaac actgttacaa gcgttatcag gttggggaca
    41281 cggagattgt ggccaatcgt gatgtgaatt ttgagattga aaagggggag ctggttatta
    41341 tccttggtgc ttcaggtgca ggcaagtcaa cagttcttaa ccttcttggg ggaatggata
    41401 ccaatgatga aggggaaatc tggattgatg gtgttaatat tgcggattat agttcccacc
    41461 agcgcaccaa ttaccgtaga aatgatgtgg ggtttgtttt tcagttttat aatctagttt
    41521 ctaatctgac agctaaggaa aatgtggaac tggcttctga aattgtgaca gatgccttga
    41581 atcctgatca ggtcttgaca gatgtaggtc tggctcatcg tctcaataac tttccagccc
    41641 agctttctgg aggggagcaa cagcgagtct ccattgcacg cgcggtagcc aaaaatccta
    41701 aaattctcct ttgtgatgaa ccgactggag ccttggatta tcagacgggc aagcaggttt
    41761 tgaaaattct ccaagacatg tctcgtcaaa agggagcgac ggtgatcatc gtgactcata
    41821 atggagcttt ggcgcccatt gctgatcgcg tgattcatat gcacgatgcc agtgtcaagg
    41881 atgtggtgct caaccagcat cctcaggata ttgacagttt ggagtactag catgatcaag
    41941 cgaaaaactt attggaagga cttaattcag tccttcacag actccaaggg gcgtttttta
    42001 tccatcttga tcctgatgat gttgggatct ctagccttag tagacctcaa agtaaccagt
    42061 cccaacatgg aggcgacagc taatgcttat ttaacaactg ctcaaacctt ggatttggca
    42121 gtcatgtcta actatggctt ggatcaagca gaccaagaag aactaaaaca gacggagggc
    42181 gcagaggtcg agtttggcta tttgacagat gtgactatgg ataatgggca ggatgccatt
    42241 cgactgtact ccaaaccaga gcgaatttca acctttcagc taagaaaggg acgacttcct
    42301 cagtcagaca gggaaatcgc tttggccact catttgcaag gccaatacag cgtgggacag
    42361 gagattagtt ttaaagaaaa agaagagggt cattcctctt taaaagacca tacttatacc
    42421 attactggtt ttgtggattc ggctgaaatc ctctcccagc gagatatggg ctacgcagga
    42481 agtggaagtg ggactctgac agcctatggg gtgattttac ctagtcaatt tgatcagaaa
    42541 gtctacaata tagctcgttt gaaatatcaa gatttagcag gtttaaatgc cttttcatca
    42601 gcttatgaag aaaaatccaa gcaacatcag gaagaccttg aacaaacttt atcagataat
    42661 ggcaaggtac gtctgcaact tttgaaaaaa gaaggacaag agtctctaga caaggggcaa
    42721 gagactcttg acaaggctca gactaatttg caggaaggca agcgtcgttt agcagctgct
    42781 caagctcgta tacaggctca agaaagtcaa ctagccttgt ttcctcaagc tcagagagag
    42841 caggctagtg ctcaacttac ccaagccaag caggaactgg gcaaggaaga ggacaaacta
    42901 aagcaagctg aacaaaatct agcccaagaa aaggaaaaat tagaaaaaca tcagcaagtc
    42961 ttggatgatt tggcggagcc aaggtatcag gtttataatc gtcagaccat gccaggtggt
    43021 cagggctatc ttatgtatag caatgcttca tccagtattc gagcagtggg caatatcttt
    43081 cctgtggtac tttatgccgt agcagccatg gtgaccttta cgaccatgac tcgctttgta
    43141 gacgaagagc gaactcatgc agggattttt aaggccttgg gttatcgtag taaggatatt
    43201 atcgccaagt ttctccttta tggactagta gctgggactg tcggaacggc tctaggtagt
    43261 atacttggtc attatttgct agccagtgta atttcaagtg tcattacaaa aggcatggtg
    43321 gtgggagaaa cccagattca gttctattgg acctatagct tactagctct tgtcttgagc
    43381 tggttggcga gtgtgttacc agcctatctg gtggcttgga gggaacttca tgacgaagca
    43441 gcccagcttc tacttcctaa acctcctgtc aaaggagcta aaatcttatt ggagcgtatc
    43501 ggttttatct ggcgtcgtct cagttttact cataaggtaa cagcccgcaa catctttcgt
    43561 tataagcaga gaatgttgat gacaatcttt ggtgtggcag gttctgtagc tctgctcttt
    43621 gcaggtttgg gaatccaatc ttctgtagca ggagttccgt ctaaacagtt tcaacaaatc
    43681 caacagtatc agatgcttgt ctctgaaaat cctagtgcga ccaatcagga caaggtagag
    43741 ctagcagaag tgttgaaagg gcaggagata ctagcctacc agaaaatcta ttctaaaacg
    43801 ctagacaagg atttcaaggg cagggctggt cttcaaaaca ttactcttat gatgatagag
    43861 aaggaagatt tgactccctt tatccatctt caacatcatc agcaggagct gacattaaaa
    43921 gatggcatcg ttattacagc taaactcgcc cagctggcag gtgtcaaggt tgggcagact
    43981 ttagaaattg aaggtaagga actaaaggtc gctgctatta ctgagaacta cgttggtcac
    44041 tttatttata tgagtcaggc tagctatgag caactttacg gacagctacc ccaagccaac
    44101 acttatctgg tctcattaag ggataccagt gcaactagta tcgaaagtca ggcgggcttg
    44161 cttatgaatc aatctgcggt gtccagtgtt gtccaaaatg cttcagccat tcgactcttc
    44221 gactctatcg ctagctcact caatcagacc atgaccatct tggtcatcgt atcggttcta
    44281 ttagctattg tcatccttta caatctgacc aatatcaacg tagctgagag aatccgtgaa
    44341 ctctccacta tcaaggttct cggttttcat aataatgaag tcaccctcta catttaccgt
    44401 gagacgattg tgctgtccct tgtgggaatc gtacttggtc tggtagctgg tttctattta
    44461 caccaatttt tgattcaaat gatttcgcct gcgactattc tcttttatcc gcaggtaggc
    44521 tgggaagtct atgtaatccc agtggcagca gtaagcatca ttttgacctt gcttggtttc
    44581 ttcgtcaatt attatctgag aaaggttgac atgttagaag ccctgaaatc tgtagagtaa
    44641 ggtagttatt tttagctgat tgaacttcta tttactaata ttcaaaaatc ctccgtttca
    44701 aagagcaggg aactctttgt gacagaggat tttttctata gggctttagc agctgcaatt
    44761 gcggcttcga agtttggctc agaattgata ttatccacgt attcaacgta gcgaatcgta
    44821 ttgtcagtat cgaggacaaa gactgcgcgt gataataggt gccattcgtt gatcaagagg
    44881 gcataatcgc gtccgaaaga atggtcaaag tagtctgaaa gcataatggc attgtcaagg
    44941 ccttcagcac cgcaccaacg tttttgagca aaaggtaggt ccattgaaac agtcaatacg
    45001 accgtgttgt ccagtccagc caattcttca ttaaaacgac gtgtttgagt tgagcagatg
    45061 cctgtatcga tagaaggaac gacactcaag acttttttct tgccatcaaa atcagccaga
    45121 gattttttag aaagatctgt tgtagtaaga gaaaaatcaa gcgccttgtc gccgacttgt
    45181 agttgtttac ctgtaaagct cacaggattt ccgagaaaag ttaccatagg atactccaat
    45241 cttttttctt ccattgtatc tgaaacagtc agaattttcc aatgatttga ccggaaatgt
    45301 gtgcatagaa aaaacgccag ctcacatgag aatgacgttt ttcagaggct tattttgcca
    45361 atccttcagc aatcttgtca aggttgtatt tcatcatgct gtagtagctg tcgccttctt
    45421 taccttgttc tgcgatagag tcagtaaaga tttgtgcgta gattgggatg tttgtgtctt
    45481 gagaaacagt tttcattgga cggtcatcca cacttgattc tacaaagagt gatggaactt
    45541 ttgtttggcg aagtttttca accaaggtct tgatttgttc aggagttcct tcttcttcag
    45601 tattgatttc ccagatgtag gcacttggga caccataggc tttagagaag tatttgaatg
    45661 ctccttcgct ggttacaatg agtttctttt cagcagggat cttattaaat ttatccttac
    45721 tttctttatc aagtttgtct aacttatcag tatattcttt gagatttttt tcatagaatt
    45781 ctttattgtt agggtctttg gcgctcaatt gtttggcgat atttttagca aaaataatac
    45841 cgttttcaag gttaagccaa gcgtgtgggt cttcttttcc tttttcattt tgaccttcaa
    45901 ggtagataac atcaacgccg tcgctgactg cgaagtagtc tttgttttca gttttcttgg
    45961 cattttctac caattttgta aaccaagcat tgccacctgt ttcaaggttg ataccgttat
    46021 agaaaatcaa atcagcctca gaagttttct taacgtcttc aggaagtggt tcgtattcgt
    46081 gtgggtcttg cccaatcgga acgatactat gaaggtcaat tttgtcacca gcaatatttt
    46141 tagtaatatc agcgatgatt gagtttgtag caacaacttt tagtttttga ccagaagttg
    46201 tatctttttt tccgctagca catgctacaa gaatgattgc agaaagaaag agaacgagta
    46261 atgtacctaa ttttttcatt agatcctcca atttattagg gctttgcccc ttattttaac
    46321 aaatgtttat ttttcagttt caaatatcgt tgtttgggag cgataaagaa gctaatgaga
    46381 aagaaactag cagctgtaag cacgatacta gaacctgccg caacattaaa actatagcca
    46441 ataaagagtc ccaaaactga agcagtagct ccgaaggttg aggaaaggaa aatcatgctt
    46501 ttcagactat tagcatacag ataagcagtt gcagctgggg taatcagcat ggctacaatc
    46561 aggatagttc cgacactttg catggctgtc acagacacga gagtcaggag taccatgaga
    46621 aggtagtgat agaaattgac aggcattccc atggctttag ccaagagttc atcaaaggaa
    46681 gttatcaaga gttgcttgaa gaaaatccag attaacaaga ggatggctgc ccccacaccc
    46741 atagtaataa acatatccgt atcttggacg gccagaatat taccaaaaag gatatggaaa
    46801 aggtcagttg aacttttagc gacaccaatc aagatgatac cgagggctaa gaaagaagaa
    46861 aaggtaatgc cgatggcggt atcgcttttg ataatcgagt ttcctttgat gtaggtaatg
    46921 atgatggcag ctagcaatcc aaagacaatg gctccgataa agaagtcaag gcccaagatg
    46981 aaggagaggg ctacacctgg taagacagca tgtgaaatgg catctcccat gagtgacatc
    47041 ccgcgtagaa taatgaaaca tcccacggct ccagctacaa tcccgacgac aatagctgtt
    47101 atcaaggcat tttgtaggaa atggaatttt tgcaatccat cgataaattc tgcaatcata
    47161 ggtcacctcc attgaaaaag agttgattac cgtaagcttc ttttagattg gtttcggtaa
    47221 aagtttcttt tgttggacca aaggcaatca cttctcgatt gacaagtaag acttgatcga
    47281 agtagtgggg aatcttgctg aggtcgtggt gaacgatgag aaccgtcttc ccagcttttt
    47341 tcaaatctct cagcgtattc atgatgattt cctcactgac agagtcaatc ccagcaaagg
    47401 gttcatccaa gaggatatag tcggcttcct gcaccaaaca tctggcaatc aagacccgct
    47461 ggaattgacc tccagacagt tgactaattt gacgttcagc gtagtcagct aggccgacga
    47521 tttcaagggc ctcttgcact ttcttccaat gtttagcctt taaacttcga aagagaggaa
    47581 tagagggaaa tagtcctaac gagacgcatt ccttgacctt gatgggaaag ttgtagtcga
    47641 tattgatttt ttgttcgaca taggcaattc ggtgtaagga ttttttaact tccttgtcat
    47701 cgagaaatgc ctgaccttga tgtgggataa ttcccagcat accttttaat agtgttgatt
    47761 tcccagcgcc gtttggacca atgatgccgg taattgttgg tccatggagc actagtgaaa
    47821 tatccttaag tgccaacgtt tctttgtagg agacactgag gttttcgata cgtatcataa
    47881 acttgtattc ctcctgtctc ttaatataca ttaaaaaaaa aattaagtca agttaatttt
    47941 tgaaaaaatt aaaataataa ctgaaaaata gattctaaag ataactttca ggataaattt
    48001 ctaaattata aaacgcatag tatgcatagt atcaagtgta aaaaacttgg aattatgcgt
    48061 tttatcatgg aaagattctt tataatagct aaaaaataat agttaaatgg ttactaattg
    48121 cattccctag tgatttttgt taagataaag gcaaatacaa atgaaagcga gaacaagatg
    48181 acacgttatc aagatgattt ttatgatgct atcaatggag aatggcaaca gacagctgaa
    48241 atcccagcag ataagtctca aacaggaggt tttgttgatt tagaccagga aattgaagac
    48301 ttgatgctgg cgacaacaga caagtggtta gcaggtgaag aagtgcctga ggatgctatc
    48361 ttggaaaact ttgtcaaata ccaccgccta gttcgtgatt ttgacaagag agaagctgac
    48421 ggtatcacac ctatcttatc actccttaaa gaatttcaag aattggagac ttttgcggat
    48481 tttatagcta aactagcaga gtttgagctt gcaggaaaac caaacttcct tccttttggt
    48541 gtatcgccag actttatgga tgctagaatc aatgttctat gggctagcgc tccaagcaca
    48601 atcttgccag atacgaccta ctatgcagaa gaacatcctc agcgcgaaga gctcttgact
    48661 ctttggaaag aaagcagcgc aaatctcctc aaggcttatg atttctctga tgaagaaatt
    48721 gaagacttgc tagaaaaaag acttgaattg gaccgccgag ttgcggcagt ggtgctctct
    48781 aatgaagaaa gttcagaata tgctaaactc tatcatccat attcttacga agatttcaag
    48841 aaattcgcgc ctgccctacc tttggatgac ttcttcaaag cagttattgg gcaattacca
    48901 gacaaggtta ttgtagacga ggaacgtttc tggcaagcag cagagcaatt ctacagtgag
    48961 gaagcctggt ctctccttaa agcaaccttg attttgagtg ttgtcaatct ttcaaccagc
    49021 tatttaacag aggatatccg tgttttgtct ggtgcctaca gccgtgccct ttctggagtt
    49081 ccagaggcaa aagataaggt caaagcagct tatcatctag cacaagaacc tttcaagcaa
    49141 gccctgggtc tttggtacgc ccgtgagaag ttctctccag aagccaaggc ggatgtggag
    49201 aaaaaagtgg caaccatgat tgatgtctat aaggagcgtc tgcttaagaa tgactggctc
    49261 actccagaaa cctgtaaaca ggctatcgtg aagctcaatg tgatcaaacc ttatattggc
    49321 tatccagaag aattgcctgc acgttacaag gataaggtag tgaatgaaac tgccagtctt
    49381 tttgagaatg ctctagcctt tgcgcgtgtg gaaatcaagc acagttggag taagtggaac
    49441 cagcctgtag attataagga atggggcatg cctgctcata tggtcaatgc ctactacaat
    49501 cctcagaaga acctgattgt ctttccagcg gccattttac aggcgccttt ctatgacttg
    49561 catcagtcat cttctgctaa ctacggtggt attggggcag tgattgccca tgaaatttcc
    49621 cacgcctttg atactaacgg ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg
    49681 acagagagcg actatgctgc cttcaaggag aaaacacaaa aagtcattga ccaatttgat
    49741 ggacaggatt cttatggagc aaccattaac ggtaaattga ctgtatcaga aaacgtggct
    49801 gacttgggag gaatcgcagc agcgcttgaa gcagctaaga gagaagcaga cttctcagca
    49861 gaagagttct tctacaactt cggtcgcatc tggcgcatga aaggtcgacc agaatttatg
    49921 aaacttttgg ctagcgtcga tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta
    49981 ccaaacttcg acgatttctt tacaacctat gatgtcaaag aaggagacgg aatgtggcgt
    50041 tcaccagagg agcgcgtgat tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc
    50101 atccaatcac gtgtgaaaac cttgatagga tgccttttgt aatagaaaga tttgctggat
    50161 agtttactta aatttcgatt gtcatcatct tgctagaaaa agggattgaa ggccttttcg
    50221 tgagcgatag tagtagctgg accatgtcct ggatagacat cgtagtttgg tagggtgaag
    50281 agttgggtct ggatactatg aaggagttgc tccatgctac cagtcggaag gtcggtccgt
    50341 ccgatagttt cgcggaatag agcatctccc gtcaagacta ggtgagcatc aggaaagact
    50401 agggaaacac caccgataga gtgccctggg gtcggtagaa ccttaaaacg aaattcctct
    50461 agttggtatt cttcgtgaaa gacaaaggtg tgttctgcag gttttgtgac cacatctgcc
    50521 atatcatcgt ggcgagggag accggagaga ttatcgacag gagtgtagag ccagctggct
    50581 tcgctctctg cgatatagac aggaggattg ccaaacgtct cgcgaaccaa gtccagactc
    50641 atgatatggt cataatgggc gtgggtcaag agaatagcac agatcggttt gttgatcttc
    50701 tcgattgtct gacgaatggc ttcccaatga ctaccaggat cgacgacgat gaggtgcttt
    50761 tcgccttcta gataataggt attttcatag gcaacaggat tcacggtttt atggattttc
    50821 atactagctc caatctcaaa gaatgtacta atactcttcg aaaatctctt caaaccgcgt
    50881 caactttatc tgcaatctca aagcagtgct ttgaacagcc tgcggctagc tttctagttt
    50941 gctctttgat tttcattgag tataaattaa gtatagcaca gttagggaga ataggtaagg
    51001 atttaaaatg aacttaaaaa ccagcatgac tagatgaaga caggctggtt atcaatttat
    51061 caatattgga aaggtgtcaa ttgcccttca taggttgcat aaactccgtc attagcttgt
    51121 ttgatagacg tgatgtttag agtgctaccg tagttggctt ctcatttgtc gctatattca
    51181 ctataagtta tcctactggg caggttctgg tcgttagcat agtattgaac gactgttttt
    51241 tatagttttg ctggctgaat aggaacaggc agcaaactcc taacattagg agagcaaaga
    51301 tagaaatagc agtttttttc ataggtattc tccttataaa ctaaaggata gaagaaagta
    51361 tcttgaggat ttttatactc ttcaaaaatc tcttcaaacc gcgtcaacgt cgccttgccg
    51421 tatatatgtg actgactttg tcagtcttat ctacaacctc aaagcagtgc tttgaacagc
    51481 ctgcggctag tttcctagtt tgctcttgga ttttcattga gtattaattc caaaatccag
    51541 tcaaggtacc agtgtatgtg atacgagttc caccgtttat ctttcgtatc ttcaatggaa
    51601 ttggggaagt cagaaagtct ttgggttaca atatggtttc cgttcttcta tctctccttc
    51661 tatcacctaa gtttaaaatc taacttcgta gtatattatg gaccaatagt tcagaattat
    51721 caagcaattt tgaattattt ttttcttatt ctgttccaat ctagttttca tattcttcaa
    51781 aaagtgataa aatggtagga agaattggag agtagagatg ccgaaagaag tgaatttaac
    51841 aggcgaagaa gttgtcgctt taaccaaaga atatttaacg gaagaggatg ttcattttgt
    51901 ccataaggcc ttggtctatg ctgttgaatg ccacagtggt caatatcgca aatcaggcga
    51961 gccttatatc attcacccta tccaagtggc aggtatttta gctaagctaa agctggatgc
    52021 tgtaacagta gcttgtggat tcttgcatga tgtggtggaa gatacagatg cgaccttgga
    52081 cgatttggaa agagagtttg gtcctgatgt gcgggtgatt gttgacggag ttaccaagct
    52141 tggcaaggtc gagtacaaat cgatcgagga gcaattagcg gaaaatcatc gcaagatgct
    52201 catggccatg tctgaggaca tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa
    52261 tatgcggacc ctgaaacatc ttcgaaaaga caagcaggag cgtatttcca aagaaaccat
    52321 ggaaatctat gccccacttg cccatcgttt ggggatttcc agtgtcaaat gggaattaga
    52381 agacttgtct ttccgttatc tcaatccaac ggagttttac aagattaccc atatgatgaa
    52441 ggaaaagcgc agggagcgtg aggccttggt ggatgaggta gtcacaaaat tagaggagta
    52501 tacgacagaa cgtcacttga aagggaagat ttatggtcgt cccaagcata tttactcaat
    52561 tttccgcaaa atgcaggaca agagaaaacg gtttgaggaa atctatgatc tgattgctat
    52621 tcgttgtatt ttagataccc aaagtgatgt ttatgccatg cttggttacg tgcatgaatt
    52681 ttggaaaccg atgccaggtc gcttcaaaga ctatattgcc aaccgcaagg ccaatggtta
    52741 tcagtctatc catacgactg tttatggacc aaaagggccg attgaattcc agattcgaac
    52801 caaggaaatg cacgaggtgg ctgagtacgg ggttgcggct cactgggctt ataagaaagg
    52861 tataaagggg caagttaaca gcaaggaatc agctattgga atgaactgga tcaaggagat
    52921 gatggagctc caagaccagg ctgatgatgc taaggaattt gtggactctg ttaaggaaaa
    52981 ctatttggct gaggagattt acgtttttac cccagatgga gctgtccgtt cccttcccaa
    53041 agattcagga ccgattgatt ttgcctacga aatccatacc aaggtcggtg aaaaagcaac
    53101 tggtgccaag gtcaatggcc gcatggttcc actgacaacc aagttaaaga caggggatca
    53161 ggttgaaatt atcgccaacc cgaactcctt tggacctagc cgtgactggc tcaatatggt
    53221 caagactagc aaggcgcgca ataagattcg ccagttcttt aaaaaccaag ataaggaatt
    53281 gtctgtcaac aagggtcgtg agatgctgat ggctcagttc caagaaaatg gctatgtggc
    53341 aaataaattt atggacaagc gccacatgga tcaagttctg caaaagacca gttacaagac
    53401 agaagactcc ctctttgcgg ccattggttt tggggaaatc ggtgcgatta ccgtctttaa
    53461 ccgtctgact gaaaaggaac gccgtgagga agagcgtgcc aaggccaagg ctgaggcaga
    53521 ggagcttgtc aaaggtggcg aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca
    53581 tgagggggga gtggttattg aaggtgcttc tggtctccta gtgcggattg ctaagtgttg
    53641 taaccccgtg cctggtgacg atattgttgg ctacattacc aagggtcgtg gtgtggctat
    53701 tcaccgtgtg gactgtatga acctgcgtgc ccaagaaaac tacgagcaac gtctccttga
    53761 tgtggaatgg gaagaccagt actctagctc aaataaggag tatatggccc atatcgatat
    53821 ctacggtctc aaccgtacag gactgttgaa cgatgtactg caagttcttt caaatacaac
    53881 caagaatatt tcaacggtca atgcccaacc aaccaaggat atgaagtttg ctaatatcca
    53941 tgtgtccttc ggtattgcca acctctctac actgaccacg gttgtcgata aaattaagag
    54001 tgtgccagaa gtttactctg tcaaacggac caacggctag ttgtcctagc tcttactaga
    54061 aaggctatta tgaaaatcat tatccaacgg gttaaaaaag cccaagtgag tatagaaggc
    54121 cagattcagg gaaaaatcaa tcagggactt ttattgctgg ttggtgttgg accagaggac
    54181 caagaggaag atttggacta tgctgtgaga aaactggtca atatgcggat tttttcagac
    54241 gcagaaggca agatgaacct gtctgtcaaa gatattgaag gagaaatcct ctctatttct
    54301 cagtttaccc tctttgcgga tactaagaaa ggcaatcgtc cagcctttac aggggcagct
    54361 aaacctgata tggcatcaga cttctatgat gctttcaatc aaaaattagc gcaagaagtg
    54421 cccgttcaga caggtatctt tggagcagat atgcaggttg agctggttaa taacggacct
    54481 gttaccatta tcctagatac taaaaagaga taagaaagac caagcccagt cggcttggtc
    54541 tttctcatcg atcataaaat actccaaaaa gaaatcggtt cttgatatgc ttgggggaag
    54601 tctcttttca ggctttggca gatgcgatag gaagggatga gatgtcctag gatgaggaga
    54661 gttccctgaa ggaaaagtgg aatatcactt aaagacacca aggagagaat catcaggcta
    54721 tcccatagga gaatttgtaa agcaaaacgc cagaatctcg gtctaatctg ggaatagagt
    54781 tgactaaagt ggtcacaaag ttggtttgaa agataggtca atagcacagg atgaaagaaa
    54841 atgagccaac cactataaat caaaatccag tcccaagtaa gccccccttt taaatgtcaa
    54901 aaatgccagc atgattccat caatgacaag gagttgaatg gttttgatga agatgatttt
    54961 tttcatgcta aaacctcctt ttccttagag acactcccat aaagagatgt gtttgtcgta
    55021 aaagtctgga tagttttctc ttaggtagtc agctgtcata taataaaaag tagaatggca
    55081 agcagtgata attgacataa gagatgaaaa acgctgagaa ctaatgaagg ctaagagaac
    55141 aaaaaataga aaatcaatgg tgagaacccc taaatagtag aagcgaatct ttttattgat
    55201 ttgaggataa atctcagcga attgatgttt gagtcggacg atcaagagaa atagcaggag
    55261 tccttgagca aggaagaaaa ttaaaccaga gagcaagagc cactcaaaag atgtctcgag
    55321 tctaatgata aaaaatgcaa atagtagcaa atcaataact gaaattgcta taaaatggat
    55381 tctatagagt tttttcatga caagacctcc ctcttttatc taacttcatt ctactctaaa
    55441 agaatgggag ttacaactaa aatgataaaa atagcagagg ggagattctc ttaagttggc
    55501 tagtattctt tatttgagtt ttcttctatt atctaacttc ttcatcattc cagacaaata
    55561 aagctccgat tgcattgagg gacagtgcaa aggcaatagt tgttacgtag gcaaggagat
    55621 tcatcttgcc cccatatccg atatagttgg tcacaaaggc aaagaggaag gcgatgatgg
    55681 aaatgatgat ggccgccaat tttacctgtt tttggctcat ttggttgggt ctgccttctt
    55741 gcgaagcttt ccatttcttt atagcaaagg tataaatgag gaaggtgacg ggataggtaa
    55801 tgatggccgc cttatttcca aggatataat cagtagcacc ggacaaaatg gtattaacaa
    55861 taccaaagta atttccccat ttgcttaatt tccccgtgaa acgagtggac aacatggaaa
    55921 tcccaacgtt ggttacggaa atcaatccaa agggtacaag agctgtccat agtccccagt
    55981 ctacaaattt atcgaggcgt gagttgagat aaccagatgc aatcgcaatc ccaacgacca
    56041 aagcaacccc gaagaggtca aatcatttag atgtagcaaa aatttttagt gattttttca
    56101 taggttaaac tacctttctt tttttcaaat attctaccac caaatgaaag taaaataaaa
    56161 tgatagaaat aaaaccctga aaataaaact ttcagggttg gtaggggact tgagaaatta
    56221 gttgattttc tcgacataga gttgttttgc aatgtccata ttcacttgta aatcctcgtc
    56281 gttactgagg atagtgaagg tattgctgaa gccatcaaac tgcttgactt ggagctggtc
    56341 accgatgtga agtgagtgct tgtccagata atggagaatg tcaaaattat cgtgcacccg
    56401 agtcaggcgg taggcgccag cttccttgat atcagctagt gggaggttat tgatttcaac
    56461 gaggagttct cccttggcag gaatagttcc tccgtggggg caggttttag ggaaacctag
    56521 cagtttatct agtctttcca cgaacaggtc agagacagtg tgttccaaga cctcagcttc
    56581 ctcgtgaatc tggtcacttg tatagtctaa atgatgaact agaaaaactt caatcaagcg
    56641 gtgcttacga tagagctcag agactagttt gagaccgagg tcagtcagta gatagccaca
    56701 ttccttgtcc tttaggatga ggttttcact tttcattcgt ttgatcattt cagttacggc
    56761 agggggagag acttgcatgc gagctgcaat ttccttgttg gtaatcttat gcaggtctat
    56821 gccaatttca taaatacatt ttagatagtc ttctttgttt ggggtcattc gtttcctctt
    56881 gtctaatatc tttatctagt atatcaaaaa aagctagatt tctctagctg tgacttttta
    56941 tgttatactt attgcaagag aaaaaacgag gagatggata tgacgaaaat agctcttctt
    57001 tcagatattc atggaaatac caccgccttg gaggctgttt tggcagatgc tcggcagata
    57061 ggagtggatg aatactggct tttgggagat attctcatgc cagggacagg gcgtagaagg
    57121 attttggact tgttggatca actaccgatt acggctagag ttttgggaaa ctgggaagac
    57181 agtctttggc atggtgtccg taaggaattg gacagtactc gccccagtca acgctatctc
    57241 ttgcgccagt gccagtatgt tttagaggaa atttccctag aagaaattga agtgctccac
    57301 aatcaatctc ttcaaattca tcgtcagttt ggggatttga cggtgggaat tagccatcat
    57361 ctgcctgata agaactgggg gcgagagttg attcatactg gcaaacaaga ggagtttgac
    57421 cgcttggtga ctcatcctcc ctgtgatatt gctgtttatg gacatattca ccagcagttg
    57481 cttcgttacg ggactggtgg gcaattgatt gtcaatccgg gttcgattgg ccaacctttc
    57541 tttttggacg ctcagctacg gaaggacttg cgggcccagt atatgatttt ggagtttgat
    57601 gacaaaggcc tggtagatat ggacttccga cgggtagact acgatgtagc agctgaattg
    57661 cagctggcta aagacctgag acttccctat tttgaggttt actatgaaag tctggtcaat
    57721 gggatccacc atactcatca tcaggaattt ttgagagaat tggctcagaa agagggctgc
    57781 gatcgggagt tagacgactg gttgaaaagt ggtaacgatt gacattacaa ctaaaaaggg
    57841 tataataata gaaaaagaag agtagaggca gggtagcctc gtaaaaagga gaagaggatg
    57901 caaattccaa gtagatttac cattgcgact catatgctga taatcattgc cctcgagggg
    57961 aaggaaagca aggtgaccag tgattttctg gctgctagtg tcggggtcaa tcctgtcatt
    58021 atcagaaaga tcttgtccca gttgaagaag gcagagctga tttcagtagc gcgtggaacg
    58081 ggcggaacag agattgtcaa ggaccttaag gatattagtc ttttagatgt ttatcaggcg
    58141 gtcgaatgtc ttggtaagac aggtcaactc ttcagtttcc atgacaatcc gaatccaaat
    58201 tgccctgtag gagctcatat tcatgatgtt ttggatcaaa aattggagag aattcagttg
    58261 actatggagg cagaacttgg tcaaaccagt ctagaaaaag tcgtggccga tgcagagagt
    58321 cagatgaagg attaagaggg ataaatgccc tcttttttct ttggataatt atgataaaat
    58381 gtagctatta aaggagtaag aaatgtatct cgttatagaa attgtattag cctttatagt
    58441 gtcattttgg aaggataata gaagtttgtg gaatccagta ttatttttat tatccctcat
    58501 ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga atgttcagtt
    58561 agctttttat gtatttgcct ttgtcttact tccttttttg ctttttctaa gtggcatctt
    58621 tttaatctat aatggggtca ttttgttgaa acgagaggga cgttccaagc cccattatct
    58681 ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact tagaatgcac
    58741 atgaaagtat gtattctagg tcttttgttt tgtatacatt taattttcaa gagtattatc
    58801 tatttttcca tgcatggtaa cgagtatcaa tcaataactg ggtaaggcga cccaaggttt
    58861 ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg tattcaagcg
    58921 cctttaagga agccaagtca ttgatagagc taataccagc atcaagaata gtgccaaaga
    58981 agaggtcgaa gtagagctga agttcttcgt cagggactgt ggccacccat tctttaaagg
    59041 ttgtgtctac ttgccggcta tcactgttgg tcttatccag ttgaacgaag tgcttgtcct
    59101 caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta ctctgaacga
    59161 tgatttggtg agcaggaatt tccagcatca taccgataat ggaaccttgt ggaatgaata
    59221 tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct tgatggagac
    59281 caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc tcaatttggc
    59341 tagcagcata gatagcgaga tttcctccct tggaatgccc agccagaata accttttgct
    59401 taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga gcaggaattt
    59461 ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca tctgtcccac
    59521 gaaagacaat cagataggta tcgaggctga cacgataagt catagccgca aattgctttt
    59581 gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg aagcgcttgt
    59641 gttgagccaa ttcatctaat aattgaaggc gatttttgct agtaagcatg gtgggctctc
    59701 ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc agattatcaa
    59761 aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag ggaaggtcgt
    59821 aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata agagctcctt
    59881 tctttttatt tatcttagca aatttccctc aaattagcta gtagcattgc ctgtttgtac
    59941 tggctaaaaa caggctattt caaattcagt ttcagaccat ctggcatgga aaaatctgtt
    60001 ataataatag aaaaggagaa gcgcatgcac aagattttat taatagaaga tgatcaggtc
    60061 attcgtcaac aggtcgggaa aatgctctct gaatggggat ttgaagtggt cctggtagaa
    60121 gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt cctcatggat
    60181 attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa gatttccaag
    60241 gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat ggcaatcaat
    60301 atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt agctaaggtt
    60361 cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct ggaatatgct
    60421 ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt cttgaatttg
    60481 accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa catcgtagca
    60541 cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga taataccctc
    60601 tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt aggatttatc
    60661 gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac aattttttct
    60721 agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttctttgg catttcttgt
    60781 cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact ttttcttctt
    60841 gtgttgcttt gtaaccatct tatttttcac ttgggacata ttggtggaaa cgcaggtcta
    60901 tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa tagctttagc
    60961 agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag cagaaagaaa
    61021 actgacggat ttgctggatt actatacctt gtgggtccat cagataaaga cccccattgc
    61081 agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc agctagaaca
    61141 ggaaattttc aaaatcgact cctataccaa cctagtttta cagtacctgc gtttagaaag
    61201 tttccatgat gatttgctct taaagcaggt tcaaattgag gacttggtca aggaaataat
    61261 tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac atgaccttga
    61321 taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa tcatctcaaa
    61381 cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc aagagctttg
    61441 tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat ttgaacgtgg
    61501 cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc tttatctatc
    61561 taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg tcggaaaagg
    61621 aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa aatagatgag
    61681 aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg cgtgatttgt
    61741 tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt tgtgtttctt
    61801 tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct ccaacaatta
    61861 attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt ttttcattgc
    61921 gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggccact tcccaagcgt
    61981 agtccacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt gccagccatg
    62041 ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc atagttgaga
    62101 taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg atgtatttga
    62161 ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt tcttcttttc
    62221 caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct tcaccttcgg
    62281 cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt tgggcatttt
    62341 cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga agagagaggc
    62401 ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac tgaagggcac
    62461 gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg ttgagtgaca
    62521 tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg tgcatcatac
    62581 cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt ttgaaaactt
    62641 ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtcc cccatgtcca
    62701 tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg taaagctcaa
    62761 cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct ttgtttacga
    62821 tgtagcgttc caattcacga cggatagtcg caccatttgg caaccagaat ggcaaacctt
    62881 gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta cggtggtcac
    62941 gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg tcaaaccaag
    63001 ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag tacgcaccag
    63061 ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga ggtccacggc
    63121 agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct tctgagtgtt
    63181 cttcaatcaa ttccaacttg taagggtcat ttttgaagat tttacgtgcc tcgtctttag
    63241 tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt tcttcttcga
    63301 tacgaggaag gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg tagtagaaac
    63361 catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga cgagctgctt
    63421 gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatcttcg tgatcaggtg
    63481 tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg agtttgccgt
    63541 tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg gcaatttcaa
    63601 aagttgttac gccagattcg aattcacgaa cagcgccatc tgggaaagta atgttaatca
    63661 tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta tcatcagact
    63721 acttccaagt cctaacgttc aattgctttt ctttatcaga gaggaagttt tccatttccg
    63781 tcagaatgtt tatatccaaa cgttgagaaa gttctaatag ccaccagata ttttctgaaa
    63841 gtttttattc cagtgtgtag ggtgtttcat catagtagcg tccttgcttt gtcatcacca
    63901 gtcgttggaa atttccaata tcattagata aagccaagag gtcttcttct accgtccact
    63961 tggaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc caactgcgct
    64021 ccactaattc ttgcaactcc ataattagta tcataataaa aaaatgcgac atcctcgaaa
    64081 ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg acacctctga
    64141 ttggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt agtatcagtt
    64201 tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga ctaagtgact
    64261 tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg tgaaagtttt
    64321 ttgtttttca ttttttgtag aatatgcttg atgctaatac cagaatccat gcccaccaga
    64381 gcaactgttt catagattag caagtaaatt agtataaact caccaaaggt tatgatagta
    64441 aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa acggtagcta
    64501 tagagtaacg atacaatcaa gattaccaga ggtgtaaaga agagaagatt gtttatatag
    64561 agtcccttga gtgtaagggg gtcagaaaca actagtaaga acaactcata aagtggccaa
    64621 taaaagaata atatgaccag atagtagggg agatgggaat agaatctacg catgataatc
    64681 acctcgttta aaaaaaacag acaacttaga tctcttgcta tgattattat agcatgttta
    64741 aaacaagaaa gtaaatttgt tgacaaagaa gatttttctt ttcactagaa tcatggttag
    64801 ttttcttggt agaaatattt tgataataat taagcaagac tattgacatt gattattaag
    64861 agtgtcacaa ttgttgtaac taaaataatt acaacaagag aggtataaaa aatgaaacta
    64921 gcagttattg cagcaaatgg acaagtgggg aaggcaattg ttgaagaagc agtcaaacga
    64981 ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaagctga gtctattatt
    65041 aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc tgttatttca
    65101 gcgtttggtg cttatacacc agatacgcta ccgctccata gcaaatcaat cgaactattt
    65161 aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggagc aggaagtctt
    65221 tatatagatg aaacaaaaac gacacgactt ttagatacgc ctgattttcc tgaagaattt
    65281 aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa aaataatctc
    65341 aactggactt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa aacaggaaac
    65401 tacattctag caggagaaat ttttactact aatgaaaaag gaataagcca gattagttat
    65461 gcagattatg ctattggatt ggtagatgaa cttgaaaaag gtcatcatat aaaagaacgt
    65521 atctctttac ttgaaaaata ataactatga gagtattaat gtttgacaga aaatttaaat
    65581 cttggtaaaa tagggattgt cgtaaagaca aataacttct tcttggttac aggcatgcca
    65641 acctgtcact cggatgaagc caaataaaaa ggagaaacat catggcaatc tcaaaagaga
    65701 aaaaaaatga aatcattgca caatatgcac gtcacgaagg tgatacaggt tcagtagagg
    65761 ttcaagttgc tgtccttact tgggaaatca accaccttaa cgaacacatc aaacaacaca
    65821 aaaaagacca tgctacttac cgtggattga tgaaaaaaat cggtcgccgt cgtaacttgc
    65881 ttgcatactt gcgtaaaaac gacgttaacc gttaccgtga gttgatcaac tctctaggac
    65941 ttcgtcgcta attcaagata caagtgctta ggccgtgttc aattgagcat atcttgataa
    66001 tgaagctact ctaaattggg tagctttttt gcgttgtcac cttacctcgc tatactcaag
    66061 tataatcttt ggttacggtt cctagcactg taaggtaaaa taaaccagct tttctccctt
    66121 cggggagatt ttttttgttt cactgaaagt ttcgtacgat cttcgcctcg tcgcctagtc
    66181 tataaacgat ttatctagca agaatcatga tgctaagggc gtcaaaaatc cgtatgaaaa
    66241 tagggaaatg acacagtgtt cgatgagcac aaggagtttc atctttttca ctaggatttt
    66301 agcccgggct caaatcagct ctctgacttc agagggcttt tttattgagg ttttatcggt
    66361 aacaattttg gagactacaa aaacctcaaa cggtatcagc taattacacc ataaaggtgc
    66421 gcagttactc ggcttttcaa gccgagtagc tgtatgcaag ccccctagaa gagcccactc
    66481 tttacaaagt aaagtatagt atgttatact ttacatggaa gtagtcactg aattccagtt
    66541 agaaattact ttgtaactac gttttgagga ggagtaaaat gctttcctac gttcgacatt
    66601 acccactagc gatagctaaa ttaatgtgtc tgtgctctcc taaaatctgc tgatttatta
    66661 ctgactaata caggagtttt ttttatggga cagacaatca tatctgctat tggtgtttat
    66721 atttccacca gtatcgatta tttaattatt ttaattattt tatttgcaca gctatcacag
    66781 aataaacaga aatggcatat ttatgcgggg caatatctag gcacaggctt acttgtaggg
    66841 gcgagtttag ttgctgctta tgtcgttaat ttcgtgcctg aagaatggat ggttggattg
    66901 cttggtttaa tccctatcta tttagggatt cgctttgcaa ttgttggaga agatgcggaa
    66961 gaagaagagg aagaaattat tgaaagatta gaacaaagca aggcaaatca actgttttgg
    67021 acagttacat tgctgacaat tgcgtctggc ggagataatt taggtatcta tataccttat
    67081 tttgcttcgt tagattggtc acagaccctc gtggccttgc ttgtgtttgt aatcggcata
    67141 attatctttt gcgagattag tcgggtgtta tcctctattc cgttaatatt cgagacaatt
    67201 gaaaaatacg agcgaatcat tgtgccctta gtattcattc tacttggact atacatcatg
    67261 tatgaaaatg gcacgataga gacttttctg atcgtgtaga tttttttgtt tcactaggat
    67321 tttagcccga gctcaaatca gctctctgat tttcagaggg ctttttcatt gagtataaat
    67381 ggacaatctt aaagttactc tattgtagag tggcttttga tttgattagg agattcttat
    67441 aaatatagta aaatgaaaca aaaacaggac aaatcgatca ggacagtcaa atcgatttct
    67501 aaaaatgttt taagaagtag aggtgtacta ttctagtttc aatttgatat ataaatgaaa
    67561 accttagctg tttggccaag gttcatttct tctatgcaag ttcttctctt ttcttatctg
    67621 ggttccagat gaagcttgcg ataaagctaa agatgatggt taggatagcg aggataatag
    67681 caaggatgag ggcagggatg cggataaacc accagagtgg atttggtttt ttatcattgt
    67741 gccattgttt cgtttcttcg tccagacgtt ggaattctgt ttgaatacga ttggcgactg
    67801 tttcaatgcc ttcatcattc attttcttga tatctgagat atcgattgga tttccaaagt
    67861 tcatatcgac acgttcacgg ctaatcaagc ccttcaaagt catgggaccg gtgtaggtaa
    67921 ccggcatgat acggaccttg gccattttgg caatcagtgc tgcgcccccc ttgacatcgt
    67981 ttgagtggcg gctaccactt ggaaacatga tgagagagcg gtcacttttt ttgagaacgt
    68041 tgataggata tttgatggct gaggcgctgg gattttcacg gtcgatggga aaggcgccac
    68101 acatacgaat ccaccaacca aagatacggt tggtaaagag ttcttttttt gccataaaga
    68161 tgaactgttt tggcttggtc gcaaaggcca tataaacagg atcccaccag gtacggtgag
    68221 gcgcaactaa aatataattt tcatcttgat taggaatttt atcagtatta tgatagtgag
    68281 cattgccatt gatggaccat aagagcaata caactaatcc acgcaaataa gtataaaaca
    68341 tgcgatctcc ttcgattgtt ttcttgttat tattatacct tatcaaagga gggctggcaa
    68401 acttttccct tgactagatg catatttggg atgaaattag aattctgtta aaaaaaatga
    68461 tataatagaa tttatggata aaaataagat tatgggatta acccaaagag aagtcaagga
    68521 aagacaggct gagggtttgg tcaatgactt taccgcatca gccagtacca gcacttggca
    68581 aatcgttaaa cgaaatgtct ttaccctttt taacgctttg aactttgcca ttgctttggc
    68641 ccttgccttt gtgcaggctt ggagcaatct ggtcttcttt gctgttatct gctttaacgc
    68701 tttttctggg attgtgaccg agctacgagc caaacacatg gtggacaagc tcaatctcat
    68761 gaccaaggaa aaggtcaaaa ccatccgtga tggtcaggaa gttgctctta atcctgaaga
    68821 attagtgcta ggagatgtca ttcgtttgtc tgcaggagag cagattccta gtgatgcctt
    68881 ggttttggaa ggctttgcgg aagtcaatga agccatgtta acgggagaaa gtgatttggt
    68941 gcaaaaggaa gttgacggct tacttttgtc aggaagtttc ctagccagtg ggtcagtttt
    69001 atctcaagtt caccatgtcg gtgcagacaa ctatgctgcc aaactcatgc ttgaggctaa
    69061 gaccgttaaa cccatcaact cccgtatcat gaaatcgctg gacaagttgg ctggttttac
    69121 tgggaagatt atcattccct ttggtctggc tctcttgctg gaagccttgc ttttaaaagg
    69181 cctgcctctc aagtcatccg ttgtaaactc gtcgacagct cttttgggaa tgttgcctaa
    69241 gggaattgcc cttttgacca ttacttcgct cttgactgca gtgattaagt tgggcttgaa
    69301 aaaggtcttg gtgcaggaga tgtactctgt tgagaccttg gcgcgcgtgg atatgctctg
    69361 tctggacaag acgggcacca tcacccaagg aaagatgcag gtggaggctg ttcttccact
    69421 gacggaaact tacggtgaag aggctattgc cagcatcttg actagctaca tggcccatag
    69481 tgaggataag aatccaactg cccaagccat tcgccagcgt tttgtgggag atgttgctta
    69541 tcctatgatt tccaatcttc ccttctccag cgaccgcaag tggggggcta tggagttaga
    69601 aggcttgggg acagttttct taggggcacc tgagatgttg ctggattctg aagtcccaga
    69661 agccagggag gccttggaga gaggatcacg tgtcttggtc ttagctctca gtcaggagaa
    69721 attagaccat cacaaaccac agaaaccatc tgatattcag gctctagcct tgctggaaat
    69781 cttggaccct attcgagagg gagcagcaga gacgctggac tatctccgtt ctcaggaggt
    69841 gggactcaag attatctctg gtgacaatcc agttacggtg tccagcattg cccagaaggc
    69901 tggttttgcg gactatcaca gctatgtaga ttgctcaaaa atcaccgatg aggaattgat
    69961 ggccatggcg gaggagacag ctattttcgg acgtgtttcc ccccatcaaa agaaactcat
    70021 catccaaacg ttgaaaaaag cgggtcatac aacggctatg acaggggacg gggttaatga
    70081 tatcttggcc cttcgtgagg cggattgttc tatcgtgatg gcggaggggg atccagcaac
    70141 ccgtcagatt gccaatctgg ttctcttgaa ctcagacttt aatgatgttc ctgagattct
    70201 cttcgagggt cgtcgcgtgg tcaataacat tgcccacatc gccccgattt tcttgataaa
    70261 gaccatctat tccttcctgt tagcagtcat ctgtattgcc agtgctttac taggtcggtc
    70321 tgaatggatc ttgattttcc ccttcattcc aatccagatt accatgattg accagtttgt
    70381 ggaaggtttc ccaccattcg ttctgacttt tgagcgaaat atcaaacctg ttgagcagaa
    70441 tttcctcaga aaatccatgc ttcgtgccct accaagcgct ctcatggtcg tctttagcgt
    70501 cctgtttgtg aaaatatttg ggagtagcca aggttggtct gagttagaaa tctcaactct
    70561 cctctattat ctcttggggt caattggttt cttatccgta tttagagcct gcatgccatt
    70621 taccctatgg cgtgtcctct tgattgtttg gtcagtagga ggtttcctag ccacagctct
    70681 cttcccaaga atccaaaaac tgcttgaaat ttcaacctta acaggacaaa cattacctgt
    70741 ttatggtgtc atgatgttgg tctttaccgt gattttcatc ctgaccagtc gctatcaagc
    70801 cagaaaataa agaaaggctg caatctgtgg attgcagtct ttttaggtac aagattgcca
    70861 gccgaaatgt ggtataataa gaggtaatag agttttggaa agtgagagaa gatgatttca
    70921 aagagattag aattggtagc ttcctttgtg tcacaggggg ctattttact agatgtggga
    70981 agtgaccatg cttatctgcc tatcgagttg gttgagagag gccaaatcaa aagcgctatt
    71041 gcaggtgagg tggtggaagg tccctatcag tctgcggtta aaaatgttga ggctcacggc
    71101 ctaaaggaga aaatccaagt ccgtttagcc aatggcttgg cagcttttga agagactgac
    71161 caagtgtctg tcattaccat tgctggcatg ggtggtcgtt tgattgctag gattttagaa
    71221 gaaggtttgg ggaagttagc taatgtagag cgtttgatcc tccagcccaa taatcgtgaa
    71281 gacgacttgc gtatctggct acaggatcat ggattccaga ttgtagcaga aagaatctta
    71341 gaagaagctg gaaagtttta tgagattttg gtggtggaag caggacaaat gaagctatca
    71401 gccagtgatg ttcgctttgg tcccttcttg tccaaagaag tcagtccagt atttgtccaa
    71461 aaatggcaaa aagaagctga gaagctagag ttcgccctcg gacaaatccc agaaaaaaat
    71521 ctggaagaac gtcaagttct agtagataag attcaagcta tcaaggaggt gctccatgtt
    71581 agcaagtgaa gtgatccaag cttatgaagc cttttgccct caggaatttt ctatggaggg
    71641 agacagccgt ggtctgcaaa ttggcacttt agacaagggt atccaaaggg tcatggttgc
    71701 cctcgatatt cgtgaagaga cggtggcaga ggccattgaa aagggtgtgg acttgattat
    71761 cgtcaagcac gcgcctatct ttcgtcctat caaggacttg cttgccagcc gtccgcaaaa
    71821 tcagatttac atcgacctga ttaagcatga tatcgcagtt tatgtcagcc ataccaatat
    71881 tgatatcgtt gaaaatgggc tcaatgactg gttttgtcag atgctaggaa tcgaggagac
    71941 gacttatctg caggaaacag gtccagaacg tggaattgga cgtattggga atattcagcc
    72001 tcagacattt tgggaattgg cccaacaggt caagcaagtc tttgacctag atagccttcg
    72061 aatggtgcat tatcaagaga atgatttgca gaagcctatt tcaagagtag caatttgtgg
    72121 tggaagcggg cagtctttct ataaggatgc tttggcaaag ggggcagatg tctatatcac
    72181 tggcgacatc tactaccata ctgctcagga tatgctgtct gatggcttgt tagcattgga
    72241 tccaggtcac tatatcgaag tgctttttgt ggaaaaaatc gcagcactcc ttactcaatg
    72301 gaaagagaaa aaaggctggg aactagagat tttacctagt caagcatcga ccaatccttt
    72361 ccgtcatatc tagttagaaa gtgaagacaa tgaaaaaagt tgccattatt ggagcaggaa
    72421 ttgtgggagc aacagctgcc tactacctct cgagagaaag tgacctagag gtgaccgttt
    72481 ttgaccatga gcaaggtcaa gccaccaagg ccgcagcagg aattatcagt ccttggtttt
    72541 ccaaacgccg taataaagcc tggtacaaga tggcgcgctt gggggctgat ttttatgtgg
    72601 atttattagc tgatttagag aaatcaggac aagaaatcga cttttaccag cgttcgggag
    72661 tctttctctt gaaaaaggat gaatccaagt tggaagaact ctatcaactg gctctccagc
    72721 gcagagaaga atctcccttg ataggccagt tagccattct ggatcaagca tcagctaatg
    72781 aattattccc tggcttgcag ggattcgaca acttgctcta tgcttctggt ggagcgagag
    72841 tagatggtca cctcttagta actcgtttgc tggaagccag tcaggtcaag ttggtcaaag
    72901 aaaaagtgac tctgacactc ttatcattag gctaccagat tggcgaagag gtgtttgatc
    72961 aggttatttt ggcaacggga gcttggttgg gggacatgtt agaaccttta ggttatgaag
    73021 tggatgtccg tcctcaaaaa ggacaactac gagattatca gcttgcccaa gacatggaag
    73081 attaccctgt tgtcatgcca gaaggggagt gggatttgat tccctttgca ggtgggaaat
    73141 tatccttggg cgctacccat gaaaatgaca tgggatttga cttgacggta gatgaaccct
    73201 tgctccaaca aatggaggag gcggccttgc ctcattaccc agttttagct agagtgactt
    73261 caaaatctga gcgtgttgga atccgtgcct acaccagtga tttctctcct ttctttgggc
    73321 aggtgcctga cttaactggt gtctatgcag ccagtggact aggttcatca ggcctcacaa
    73381 ctggtcctat tattggttac catttagctc aactgatcca agacaaggag ttgaccttgg
    73441 accctgaaaa ctacccaatt gaaaactatg tcaaacgagt aaaaagcgaa taatactcaa
    73501 tgaaaatcaa agaacaaact aggtaactag ccgcgggtta ctcaaagcac tgctttgagg
    73561 ttgtggatag aactgatgaa gtcagtaacc atacccatgg caaggcgacg ttgacgtggt
    73621 ttgaattgga ttttcgaaga gtataagcat tttactgaaa ttttatcagg tagtttagga
    73681 tggcaaatga cattccctgt caaaaatggt aaaataagaa aaaataatct gagaatcgag
    73741 gaaaaaagat gcaagaaaag attttggtaa ctggtggtgc cggttttatt ggaacccaca
    73801 ctgttattga attgatccaa gcaggccatc aagttgttgt ggtggataat cttgtcaata
    73861 gcaatcgtaa gagtttagaa gttgttgaaa gaatcacagg agttgagatt cctttctatg
    73921 aggcagatat tcgtgacaca gataccctca gagatatttt caagcaggaa gaaccgactg
    73981 gtgtcattca ctttgctggt ttgaaggctg ttggcgaatc aacacgtatc cctcttgcct
    74041 actatgacaa caatatcgct ggaactgtca gccttttgaa agtcatggaa gaaaacaact
    74101 gtaaaaacat catcttcagt tcttctgcga cagtttacgg ggatccgcac acagtgccca
    74161 tcttggaaga tttcccactt tcagtgacca acccatacgg tcgtactaag ctcatgctag
    74221 aggaaatttt gactgatatt tacaaagcag actcagaatg gaatgttgtc ttgcttcgtt
    74281 actttaaccc aatcggagcc catgagagtg gtgatttggg agaaaatcca aacggtattc
    74341 caaacaatct cttgccatat gtgactcaag tagccgttgg aaaattagag caagtgcaag
    74401 tgtttggaga cgattacgat acggaagatg gaacaggtgt tcgtgactat atccacgttg
    74461 tcgatttggc taagggtcac gttgcagctt tgaaaaaaat ccaaaaaggt tcaggactaa
    74521 acgtttataa ccttggaact ggtaaaggtt actcagttct tgaaattatc caaaacatgg
    74581 aaaaagcggt gggacgtcct attccttacc gcatcgtaga acgtcgccca ggtgatatcg
    74641 ctgcctgcta ctcagaccca gcaaaagcta aagcagaact cggttgggaa gcagaactcg
    74701 acatcaccca aatgtgtgaa gacgcatggc gttggcaaag caagcatcca aatggatttg
    74761 aagactaaga tgatgatttc aatcatcgtc ccttgtttaa acgaagagga agtacttcct
    74821 cttttttatc aggctctgga agctttactt ccagatttgg aaacagaaat cgagtatgtc
    74881 tttgtcgatg atggatcaag tgatgggacc ttggaactct taaaggccta tcgggagcaa
    74941 aatccggcag tccattatat ttctttctct cgaaattttg gcaaagaagc agccctttat
    75001 gcaggcttgc aatatgcgac aggagatttg gtggtggtga tggatgcaga cctccaagat
    75061 cctcctagta tgttgtttga gatgaaaaat gtactagaca aaaatgtaga cttggactgc
    75121 gttgggacac ggagaattag tcgggaggga gaacccttct ttcgcagttt ctgtgctgtt
    75181 ctcttttatc gcctcatgca aaaaatcagc ccagtagctc tgccgtcggg tgtccgtgat
    75241 tttcgtatga tgagaaggtc tgtggtcgat gccattttaa gtttgactga gtccaatcgt
    75301 ttttctaagg gactctttgc ctgggtcggc tttaaaaccc actatctgga ctatccaaat
    75361 gtcgaaaggc aggctggcaa gaccagttgg agttttaggc aactcttttt ctactccatt
    75421 gaagggatta ttaatttttc agattttccc ttgattatag cctttgtagc tggtctccta
    75481 tcttgttttc tttctctgct gatgaccttt tttgttgtgg ttcggaccct cattttgggc
    75541 aatccgacat cgggttggac ctctctgatg gctgtcattc tctttcttgg aggcattcaa
    75601 ctcttgacca ttgggattct cggcaagtat atcagtaaga tttatttaga gactaaaaaa
    75661 agaccacttt atcttatcaa agaaaaaagt gaccttcctg attttacaga aaaaaataaa
    75721 gtgaaaagac tataatttta catggaaatg tgctaaacta gagggagtgg attatcgcca
    75781 ttgatttagg cttcctggtt tccaatcagg gcgcgagttg ggcaattttt aacagcctct
    75841 aagacatcct gactaggaga aatttctttt tccagttggt cagggtcatc gtaaaaacgc
    75901 acgattccat tatcgtggta atcaaataaa tcagaataag tttggcaaag cccacaggcg
    75961 atacatcgtt caggtataag tgtgattttc atgttcatat ttatattgta ataagaaaag
    76021 taaaaaaaaa caaggagtaa ggtatggcaa aagaaccgtg gcaagaagat atctatgatc
    76081 aagaagaatc aagagcagag cgtcggcatc gaaaccacgg aggggctgat aggatggcta
    76141 atcgtatttt gacgatccta gctagtattt tctttgtaat tgtggtggtg atggtcatcg
    76201 ttctcatcta tctatcatcg gggggaagta atcgcacagc agccttaaaa gactttcatg
    76261 attctgatgc aagtgtagta caaatctcat cttcaagcag ttctcagcct gagcagagtt
    76321 cagagccaga atctacttct agtagttcag aagaagctgc taatcctgaa ggaacgatta
    76381 aagttctcgc aggagaaggg gaagcagcta ttgccgctcg tgcaggaatc tccattgctc
    76441 agttagaggc cttgaatcct gggcacatgg ctacaggatc ttggtttgct aatccaggtg
    76501 atgttataaa aataaaatag gagccgatat gaaaacaatt caaattgcta ttgatggtcc
    76561 tgcttccagc ggtaagagta cggtcgcaaa gattattgct aaggattttg gattcaccta
    76621 ccttgataca ggagctatgt atcgtgcagc gacctatatg gctcttaaga accaattagg
    76681 agttgaagaa gtcgaagccc ttctagcctt gttggaccag catccaatca gctttggacg
    76741 ttcagaaact ggagaccagc ttgtttttgt aggagatgtg gatattaccc atcctatccg
    76801 tgaaaatgaa gtgaccaatc atgtttctgc tattgcagca attcctgaag tgcgtgagaa
    76861 actggtttct ctccaacaag aaattgccca gcaaggcggg attgtcatgg atggtcgcga
    76921 tattggaact gttgtattgc cacaagcaga attgaaaatt ttcctagtag cttctgttga
    76981 tgagagagca gagcgtcgtt acaaggaaaa tattgccaag ggaattgaaa cagaccttga
    77041 aaccctaaaa aaggaaattg ctgcgcgtga ctacaaggat agtcatcgtg agacttctcc
    77101 tctcaaacaa gcagaggatg ctgtctacct tgatacaact ggtttgaaca ttcaagaagt
    77161 agttgaaaaa atcaaagcag aagctgaaaa aagaatgtaa atgtagaaaa gccgatagat
    77221 tgatatcggt ttttttctaa atttgtcaaa atgctgattt tagggtataa tagttgctgt
    77281 tcgagaaatt ttgattttca aagaatagtg aatgatgata aggagaaatc atgaacaatt
    77341 taccaaattg tccaaaatgt aactcagagt atgtctacga agacggtgct ctactggttt
    77401 gcccagagtg tgctcatgag tggaatcctg ctgaagttgc agaagtagaa gaaggtcttg
    77461 tcgctatcga tgccaacgga aataaattga ctgatggtga tacagtaact ctcatcaagg
    77521 acttgaaagt aaaaggtgcg ccaaaagatt tgaaacaagg gacgcgcgtg aaaaatatcc
    77581 gcatcgtaga aggcgatcac aatatcgact gtaagattga tggttttggt gccatgaaac
    77641 ttaaatcaga gtttgtgagg aagatttaag catgtcaaaa cactataaac ttgtatttta
    77701 tagccgtatc ttcttgtttc tagcggcttt tacgggagtt tatcttgaaa ttactaggca
    77761 tggtggtttt gggatgcttc tctattacac ggttctgtcc aacctcttgg taactatttt
    77821 taccctttat cttctaaagg ttatgagccg tgtaggtgaa aattggcaaa ggccaagtct
    77881 cttgcgctta aaaggtgggg tcaccatgag tatcatgatt acctgtgtga tttaccattt
    77941 cctcttggcg cccattgcga ctaatttcta taccctagaa aatttccttt gccactatat
    78001 cgttcccatc tggtttttag cggataccct cttttttgac aaacagggtc aatacaagat
    78061 ttgggatcca gcagtgtgga ccattttacc ctttctgtat atgatgtttg ctctttttaa
    78121 tggcttggtt ctaaaactca atattccaaa tgccaaggat aatcctttcc cttacttctt
    78181 tttgaatgtg aacaagggtt ggaatgttgt gtttaagtgg tgtctgatta tctttgttgc
    78241 ctatatggta gcaggattta ttttctactt tatcaagcaa atcaagagaa agtcatccta
    78301 atactcttcg aaaatctctt caaaccacgt cagtttccat ctgcaacctc aaaacactgt
    78361 tttgaacaac ctgcggctag cttcctagtt tgctctttga ttttcattga gtataagata
    78421 caagggattc attttcgaat ttaagaagga gtctacaaac caatgaggct tcttcttttc
    78481 ttgcttattt gataactatc aaaaaagtag aagattaaga gaaatataga aagagatttc
    78541 atgaaacaat ttttagaacg ggccagcatt ttggctctct ccctcgtttt gattacctcc
    78601 ttttccattt cgagtgccct accagccatg tttgactatt atcagggtta ttctaaggaa
    78661 caaattgagc tcttggtgag cttgccttcc tttggaatca tgatgatgtt actgctaaat
    78721 ggtttcttag aaaaaatatt tcctgagcgc ttacagatta gtttgggctt gctgatttta
    78781 tcattgagcg gtacagctcc cttctggtac caagcctatc cctttgtctt tggaacacgg
    78841 cttctctttg gtttgggtct tgggatgatc aatgccaagg ccatttctat tatcagtgaa
    78901 cgctaccaag gaaaaaggcg aattcagatg ttagggctac gcgcttctgc agaggtcgtt
    78961 ggagcttctc tcattacctt ggccgtcggt cagttgttgg cctttggttg gacagctatc
    79021 tttctagcct atagtgctgg atttttggtg ctgccccttt atctgctctt tgtcccttat
    79081 ggaaaatcaa agaaagaagt caagaaaaga gcgaaggaag caagtcgttt aactcgagaa
    79141 atgaaaggct tgatttttac cttagctatc gaagcggcag ttgtagtttg taccaataca
    79201 gctattacca tccgtattcc aagtttgatg gtggaaagag gattggggga tgcccagtta
    79261 tctagttttg ttcttagtat catgcagttg atcgggattg tggctggggt gagtttttct
    79321 ttcttgattt ctatctttaa agagaaactg ctcctctggt ctggtattac ctttggcttg
    79381 gggcaaattg tgattgcctt gtcttcatcc ttgtgggtgg tagtagcagg aagtgttctg
    79441 gctggatttg cctatagtgt agtcttgacg acggtctttc aacttgtctc tgaacgaatt
    79501 ccagctaaac tcctcaatca agcaacttca tttgctgtat taggctgtag tttcggagcc
    79561 tttacgaccc catttgttct aggtgcaatt ggcttactaa ctcacaatgg gatgttggtc
    79621 tttagtatct taggaggttg gttgattgta atctctatct ttgtcatgta cctacttcag
    79681 aagagagctt aggattgatt cctaagtttt tcttttgata ctcaatgaaa atcaaagagc
    79741 atggttgatt gagtttggaa tagtacgctg tagttgctaa aatatttcta gaaattaatt
    79801 tgacttttct aatagagtta ttcatatctt atttcaatct actatagaaa gctagccgca
    79861 ggttgctcaa aatagtgttt tgaggttgca gatggaaact gacgtggttt gaagagattt
    79921 tcgaagagta tgagattttt atacccatac aatatttgtt ttaggtcctt gtttacagac
    79981 taatttcttg ataaaataga ggttatgacg agatataaag caactatttc ctatgatggt
    80041 tatgcctttg ctggctttca gcgccagtct catgcgcgta gcgttcagga agaaattgaa
    80101 aaaaccttga ccagattaaa taaagggcaa accattactg ttcacggtgc tggtaggaca
    80161 gatagtgggg ttcatgccct gggacaggtc attcattttg acctgcctta tcagatggat
    80221 gaggagaaac tccgttttgc cttggatacc cagtctcctg aagatattga tgtgatttcg
    80281 attgagcttg tggcagatga ttttcattgc cgttatgcca aacatagcaa gacctatgag
    80341 tttattgtgg atagaggacg tcccaaaaat cctatgcgcc gtcactatgc cacccacttt
    80401 ccctacccac tcgatgtgga acgaatgcag attgcaatca aaaagctaga gggaacccat
    80461 gattttaccg gttttacagc ctctgggact agtgtagagg ataaggttcg caccatcaca
    80521 gaagctagtt taatagtcga tgagacagga caatttttga cctttacctt ttcaggaaat
    80581 ggtttcttgt ataaacagat tcgcaatatg gtggggactc ttctcaaaat cggtaacaac
    80641 cgcatgccag tagagcagat tgatctcatc ttggagaaga aggacaggca acttgcaggt
    80701 cccactgcag caccaaatgg tttgtattta aaggagattc gttatgaaga ataatcgtat
    80761 tttagcactt tctggaaatg atatttttag tggtggtgga ctgtcagctg atttggctac
    80821 ctataccttg aacggcttgc atgggtttgt agcagtgact tgtttgacag ccttgacaga
    80881 aaaaggattt gaagtctttc caactgatga taccattttt caacatgaat tagatagctt
    80941 gcgtgatgtg gaatttgggg gaattaagat tggtcttctc cctactgtca gtgtggctga
    81001 gaaggccttg gactttatca aacaacgccc aggagtacct gtggtgttgg atcctgtctt
    81061 ggtctgcaag gaaacgcatg atgtagctgt cagtgagctc tgccaagagt tgattcgctt
    81121 tttcccttat gtcagtgtga ttacgcctaa tctcccagaa gcagaattat tatccggtca
    81181 ggaaattaaa accttggaag acatgaaaac tgcagcgcag aaattgcatg atttaggagc
    81241 gccagcagtc attatcaagg gaggcaatcg tcttagtcag gacaaggctg tggatgtctt
    81301 ttatgatgga cagaccttta ctatcctaga aaatccagtt atccaaggcc aaaatgctgg
    81361 tgcaggttgt acctttgcct ctagcattgc cagtcacttg attaaaggtg ataaactttt
    81421 gccagcagta gaaagctcta aggctttcgt ttatcgtgct attgcacaag cagatcagta
    81481 tggagtaaga caatatgaag caaacaaaaa caactaaaat cgcccttgta tccctattaa
    81541 ccgccctttc tgtggttcta ggttatttct taaaaatccc aacacctaca ggaattctaa
    81601 ctcttttaga tgctggtgtc ttctttgcgg ccttttactt tggtagtcgt gaaggagcgg
    81661 tagtcggagg actagcaagt ttcttgattg acctcttatc aggctaccct cagtggatgt
    81721 tctttagctt ggtcaaccat ggcttgcagg gatttttcgc aggatttaaa ggaaaaagtc
    81781 agtggttagg ccttatttta gcaactattg ccatggtagg aggctacgcc ttgggttcta
    81841 ctttgatgaa tggctgggca gcagccctcc cagaaattct accaaatttc atgcaaaata
    81901 tggtagggat gattgtagga tttattctta gtcaaagtat caagaagatt aagtaatact
    81961 cttcgaaaat ctcttcaaac cacgtcagtt tccatctgca acctcaaaac actgttttga
    82021 gcagcctgcg gctagctttc tagtctgatt ttcattgagc ataaagaggt tgagtaaaaa
    82081 gtctttcaaa taagaaaaac gcatagtatc aggtgttgaa tgaacacctg atactatgcg
    82141 ttttattgtg ggaagatttt cctcattttc tagtgaaatt gaactttttc taacat
//
LOCUS       DAVEHY010000005        80563 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVEHY010000005 DAVEHY010000000
VERSION     DAVEHY010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80563
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.005"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(48..1067)
                     /gene="adhP"
                     /locus_tag="VUZ44_000411"
     CDS             complement(48..1067)
                     /gene="adhP"
                     /locus_tag="VUZ44_000411"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU0319383.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(1406..2218)
                     /locus_tag="VUZ44_000412"
     CDS             complement(1406..2218)
                     /locus_tag="VUZ44_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU0319384.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            2408..3826
                     /locus_tag="VUZ44_000413"
     CDS             2408..3826
                     /locus_tag="VUZ44_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU0319385.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            3879..4586
                     /locus_tag="VUZ44_000414"
     CDS             3879..4586
                     /locus_tag="VUZ44_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0319386.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLAFVVIMSRTLGISV"
     gene            4681..5655
                     /gene="folP"
                     /locus_tag="VUZ44_000415"
     CDS             4681..5655
                     /gene="folP"
                     /locus_tag="VUZ44_000415"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU0319387.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            5657..6979
                     /locus_tag="VUZ44_000416"
     CDS             5657..6979
                     /locus_tag="VUZ44_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU0319388.1"
                     /translation="MKEIENNQWIANYWTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYFIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            6960..7514
                     /gene="folE"
                     /locus_tag="VUZ44_000417"
     CDS             6960..7514
                     /gene="folE"
                     /locus_tag="VUZ44_000417"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU0319389.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            7557..8369
                     /gene="folK"
                     /locus_tag="VUZ44_000418"
     CDS             7557..8369
                     /gene="folK"
                     /locus_tag="VUZ44_000418"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU0319390.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLET
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(8414..8731)
                     /locus_tag="VUZ44_000419"
     CDS             complement(8414..8731)
                     /locus_tag="VUZ44_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU0319391.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            9087..9533
                     /gene="rplM"
                     /locus_tag="VUZ44_000420"
     CDS             9087..9533
                     /gene="rplM"
                     /locus_tag="VUZ44_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU0319392.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            9552..9944
                     /gene="rpsI"
                     /locus_tag="VUZ44_000421"
     CDS             9552..9944
                     /gene="rpsI"
                     /locus_tag="VUZ44_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU0319393.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(10207..11427)
                     /locus_tag="VUZ44_000422"
     CDS             complement(10207..11427)
                     /locus_tag="VUZ44_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014619928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU0319394.1"
                     /translation="MSVTKTNSNTYNLKVYIPKEIRPKMGIKGNHFVKRYKTRKEAKE
                     AELEILTKIHQLENGEDIPLPKTSDILFSEFFNNIWWDSYKAGQTTSTTKPPTQATID
                     NTETVFRKHILPMFGNYSINFLNQNKQVVLNLMTAKAEEYANFKVIRSYVNSIFDWAE
                     ELEYIESNRLSKTIKRIKATKKLKLQESKNEEDLYLSSEELQDWFDAFREDLENDKLS
                     LKDYVLFFTTFILSDRKSESYALHWKNIDLANAQIDLRHALDKYKNVKSTKGNKKTIF
                     SIPSYLVSLLSEWKKQQKYELAKFGIMQTSDQLVFTYIDTKGNVNSPLHVDYLNNKMN
                     SVKRRHPKLKHATPHKLRHTGATLAKKAGMSLEAISEALTHSDTITTKTYVNTSNIVP
                     LSAGQVAYQHLKNK"
     gene            complement(11469..11738)
                     /locus_tag="VUZ44_000423"
     CDS             complement(11469..11738)
                     /locus_tag="VUZ44_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0319395.1"
                     /translation="MQVILPTEQVQEIQSMITNLLQNEISHFKEDLGLDSPYLNKGQT
                     CKYLGISNNTLDGWIQKGLPVIKIGKTVRFNKNEIDKWLCRKAML"
     gene            complement(11746..12540)
                     /locus_tag="VUZ44_000424"
     CDS             complement(11746..12540)
                     /locus_tag="VUZ44_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEU0319396.1"
                     /translation="MSYNRKIIRTSSYLEIWEYESPIFSNDTTQIDEEHISLKEKKKR
                     RTFEELTTAEQDERIKRISNTRKNSKWKLQRLIDTNFDDRTSFLTLTTKENIQNRYEF
                     NLLFDKFIKRLNYHIYHSKKRLIKYIAVLERQKRGAWHAHILLFSFPFIPHKELLTIW
                     GLGAVRINKLNDLDDSSNAGRYVAKYMEKGIGQELLESLGKKAFYSSRNLQKPEEIKL
                     FTSESLDNLVKNEDILYESNYISKVFRKGHLIDNKVKYKKIKLNKE"
     gene            complement(12712..13485)
                     /locus_tag="VUZ44_000425"
     CDS             complement(12712..13485)
                     /locus_tag="VUZ44_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU0319397.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYDWKIEKELNSIEVINLMGNHDVYYLLGEQVPFSIQNLEVFFAV
                     QQLLQDLNLQVAYQLDDYLVSHAGFNLLFDPKEWHFKPFTEEYEEELEILANAVGYMR
                     GGGDMAGSPLWAHFRELELIPNNNYPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTDWATDQTLKQLPKPQI"
     gene            complement(13561..14289)
                     /locus_tag="VUZ44_000426"
     CDS             complement(13561..14289)
                     /locus_tag="VUZ44_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU0319398.1"
                     /translation="MAKLFAISDIHGHYNEFIKSLNKIDLSDKQSKLILLGDYIDNGH
                     QSFQVISKIIELEELHPNQIITLLGNHEEWFYDWLILENPTSSSFSETIKSFFSPEEL
                     TYILKSNVNNFEAGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GKLWKDLTSSEMFTNKFPLTTGEFFKDIVSGHVASWEVAKDKAYQGKIYHDSKSHYFI
                     DGDVKNSKTIPVICYDTVTKSYQY"
     gene            complement(14306..14620)
                     /locus_tag="VUZ44_000427"
     CDS             complement(14306..14620)
                     /locus_tag="VUZ44_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319399.1"
                     /translation="MKINDFLKPELLGNKFVAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQIKVNTLSPTATPQLLSDKKTCPIKLSNLTVGQFNGNLWFSCNDVVPI
                     SK"
     gene            complement(14717..16036)
                     /locus_tag="VUZ44_000428"
     CDS             complement(14717..16036)
                     /locus_tag="VUZ44_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="otitis media-associated H10"
                     /protein_id="HEU0319400.1"
                     /translation="MFKLKKEANLKRNYFITSSRLKLLHLIIIIFSIFVLLGLIVSIR
                     APAFIQILCIVFGVLAIYKINNKLKDFRYELDFDLIIRESLLFGLYTNHLYTSEKDNS
                     GYEEIIRSAILKYELDNQNGRIIIKALIRGDEFSKKVQTLDDVLAGVLELELEEKITH
                     PNIVEYHFYYKKPDRLILSPHDHKKEIDSLDIDLGYDITYNPIKCPHILVSGGTGSGK
                     SIFISFLIIELLKRNSTLYIADPKNSDLGSLSHYLSDKYVATTPNSIARIVRLVVEQM
                     QARYQTMRDNFHYGSNFADHGFKPVWLIFDEMGAFQASATDKKSKEVITEVMDGIKQI
                     ILLGRQAGVFILISAQQMRAETLNTDLRDNLGLRIALGANSIEGYRMVFGTATPDKFK
                     SIEEKGAGYLYMQGSGKEKAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            complement(16113..16583)
                     /locus_tag="VUZ44_000429"
     CDS             complement(16113..16583)
                     /locus_tag="VUZ44_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319401.1"
                     /translation="MVRVYKSVRLAYEAKVWIDELIQNKERKIKELSQNNFLSTLEQT
                     LLSNHYDELNGVSFNIVLKASIGSVIEESYRNTKHYSIDEWQKLRQEMEKDIKNVNPS
                     LETSVTPRLYLDENVLNGLDEFRYHLMKEDGATRLPRLSYIIKLVVYSYWKTQQ"
     gene            complement(16596..17396)
                     /locus_tag="VUZ44_000430"
     CDS             complement(16596..17396)
                     /locus_tag="VUZ44_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319402.1"
                     /translation="MKYCDENNIKPWEWDFKNHSLSPLPNDSITAFLKYRQLPENEGI
                     DCDKAAFFLYKCLGWQESQDSTIRGETMNSFITIFKEAIGNSSNFDEESTKLGITKKK
                     IPISVLCEHQNYLKFETIQNNLENFKLFARTTHTIGNFTVFPNWMNCGRGLRLGDYWD
                     ITLISLQEFLNILSPEAWENFIKMYHLQPYVNSDYSVELFWDNHNNNAIRPTKEENFQ
                     IFLKKVNERIEERGKFIIKQICDQLDQKDFNFYKEIENMDKIKFSNEF"
     gene            complement(17741..18352)
                     /locus_tag="VUZ44_000431"
     CDS             complement(17741..18352)
                     /locus_tag="VUZ44_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319403.1"
                     /translation="MGTWKPSREERVKIGIETFKNHPIDKSFNEYYLEVRKHVETCLK
                     PLSELPGYEASNIKYHILNVDLSKQKDFTTKVGECLFVQFTEDGHIVVIGAGHDYGMP
                     TSNKYIGANIINKLGNKWSKNAILIFITGIRQVGSYGKGSGIGGLEHKFQSRNMIEMY
                     IGEYILKQGIAILDKYSHKNYKLTPDEWDDETDKIFNYYNINN"
     gene            complement(18399..18794)
                     /locus_tag="VUZ44_000432"
     CDS             complement(18399..18794)
                     /locus_tag="VUZ44_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319404.1"
                     /translation="MEIYTYSDFLKDKTALTFEEAGEIYNNLVSSLNTKDPDFLENWT
                     TLIELAAQYTELRVRSETIPLPKREQNDISRKSTHKAFISQLKVIKYFSENDGKNTNW
                     FDQITNDRQRQGDFANYLAYIYSVNTRKK"
     gene            19540..19692
                     /locus_tag="VUZ44_000433"
                     /pseudo
     CDS             19540..19692
                     /locus_tag="VUZ44_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            19848..20186
                     /locus_tag="VUZ44_000434"
     CDS             19848..20186
                     /locus_tag="VUZ44_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU0319405.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            20376..21860
                     /locus_tag="VUZ44_000435"
     CDS             20376..21860
                     /locus_tag="VUZ44_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU0319406.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFAAQDKEDLLGGTVDYIDFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVEYAKQTEIILSLFSILG"
     gene            21864..22103
                     /locus_tag="VUZ44_000436"
     CDS             21864..22103
                     /locus_tag="VUZ44_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU0319407.1"
                     /translation="MIGSIAAILTTFAFLPQVFRIVKTKDTGSIALGMYVMQVIDIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            22233..22547
                     /locus_tag="VUZ44_000437"
     CDS             22233..22547
                     /locus_tag="VUZ44_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU0319408.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            22665..24644
                     /locus_tag="VUZ44_000438"
     CDS             22665..24644
                     /locus_tag="VUZ44_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU0319409.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDATERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            24654..24968
                     /locus_tag="VUZ44_000439"
     CDS             24654..24968
                     /locus_tag="VUZ44_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU0319410.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            24999..25520
                     /locus_tag="VUZ44_000440"
     CDS             24999..25520
                     /locus_tag="VUZ44_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319411.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFISPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKSGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKFINEQIRLINNLSN
                     WKRTHLVYNPDLV"
     gene            25584..26930
                     /gene="celB"
                     /locus_tag="VUZ44_000441"
     CDS             25584..26930
                     /gene="celB"
                     /locus_tag="VUZ44_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU0319412.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVF
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            27310..27486
                     /locus_tag="VUZ44_000442"
     CDS             27310..27486
                     /locus_tag="VUZ44_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319413.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            27887..30100
                     /locus_tag="VUZ44_000443"
     CDS             27887..30100
                     /locus_tag="VUZ44_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU0319414.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(30322..30798)
                     /locus_tag="VUZ44_000444"
     CDS             complement(30322..30798)
                     /locus_tag="VUZ44_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU0319415.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            31021..34224
                     /locus_tag="VUZ44_000445"
     CDS             31021..34224
                     /locus_tag="VUZ44_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU0319416.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKHGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            34605..34990
                     /gene="tnpA"
                     /locus_tag="VUZ44_000446"
                     /pseudo
     CDS             34605..34990
                     /gene="tnpA"
                     /locus_tag="VUZ44_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(35369..35998)
                     /locus_tag="VUZ44_000447"
     CDS             complement(35369..35998)
                     /locus_tag="VUZ44_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU0319417.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(36008..37009)
                     /locus_tag="VUZ44_000448"
     CDS             complement(36008..37009)
                     /locus_tag="VUZ44_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU0319418.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSIDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(37040..37681)
                     /locus_tag="VUZ44_000449"
     CDS             complement(37040..37681)
                     /locus_tag="VUZ44_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU0319419.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVICGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(37700..38515)
                     /locus_tag="VUZ44_000450"
     CDS             complement(37700..38515)
                     /locus_tag="VUZ44_000450"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU0319420.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            38787..39221
                     /locus_tag="VUZ44_000451"
     CDS             38787..39221
                     /locus_tag="VUZ44_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU0319421.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFELGI"
     gene            39233..40423
                     /locus_tag="VUZ44_000452"
     CDS             39233..40423
                     /locus_tag="VUZ44_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEU0319422.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            40434..40925
                     /locus_tag="VUZ44_000453"
     CDS             40434..40925
                     /locus_tag="VUZ44_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU0319423.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            40940..41719
                     /locus_tag="VUZ44_000454"
     CDS             40940..41719
                     /locus_tag="VUZ44_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU0319424.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            41706..42524
                     /locus_tag="VUZ44_000455"
     CDS             41706..42524
                     /locus_tag="VUZ44_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU0319425.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            42524..42817
                     /gene="yajC"
                     /locus_tag="VUZ44_000456"
     CDS             42524..42817
                     /gene="yajC"
                     /locus_tag="VUZ44_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU0319426.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHYIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            42839..44740
                     /locus_tag="VUZ44_000457"
     CDS             42839..44740
                     /locus_tag="VUZ44_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU0319427.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNQEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEVLTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            44800..45801
                     /locus_tag="VUZ44_000458"
     CDS             44800..45801
                     /locus_tag="VUZ44_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU0319428.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(45911..46246)
                     /locus_tag="VUZ44_000459"
     CDS             complement(45911..46246)
                     /locus_tag="VUZ44_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319429.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLTYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(46257..46499)
                     /locus_tag="VUZ44_000460"
     CDS             complement(46257..46499)
                     /locus_tag="VUZ44_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319430.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(46510..47052)
                     /locus_tag="VUZ44_000461"
     CDS             complement(46510..47052)
                     /locus_tag="VUZ44_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU0319431.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIRNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(47068..47262)
                     /locus_tag="VUZ44_000462"
     CDS             complement(47068..47262)
                     /locus_tag="VUZ44_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319432.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            47428..48378
                     /gene="rsmH"
                     /locus_tag="VUZ44_000463"
     CDS             47428..48378
                     /gene="rsmH"
                     /locus_tag="VUZ44_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU0319433.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            48390..48707
                     /gene="ftsL"
                     /locus_tag="VUZ44_000464"
     CDS             48390..48707
                     /gene="ftsL"
                     /locus_tag="VUZ44_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU0319434.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            48711..50963
                     /gene="pbpX"
                     /locus_tag="VUZ44_000465"
     CDS             48711..50963
                     /gene="pbpX"
                     /locus_tag="VUZ44_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU0319435.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSIFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            50965..51945
                     /locus_tag="VUZ44_000466"
     CDS             50965..51945
                     /locus_tag="VUZ44_000466"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU0319436.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            52085..52273
                     /locus_tag="VUZ44_000467"
     CDS             52085..52273
                     /locus_tag="VUZ44_000467"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319437.1"
                     /translation="MLEIDLTVLIDLSCSYFILLYSFEMVDRTDEVSSKHGFEVVDKE
                     KLMWFEEVFEECKKILVS"
     gene            52554..54659
                     /locus_tag="VUZ44_000468"
     CDS             52554..54659
                     /locus_tag="VUZ44_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU0319438.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            55111..55446
                     /locus_tag="VUZ44_000469"
                     /pseudo
     CDS             55111..55446
                     /locus_tag="VUZ44_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(55513..55995)
                     /locus_tag="VUZ44_000470"
     CDS             complement(55513..55995)
                     /locus_tag="VUZ44_000470"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU0319439.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(56090..57574)
                     /locus_tag="VUZ44_000471"
     CDS             complement(56090..57574)
                     /locus_tag="VUZ44_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU0319440.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDNEAAVEASKQEIIRRYYQTILDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            57727..59334
                     /locus_tag="VUZ44_000472"
     CDS             57727..59334
                     /locus_tag="VUZ44_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU0319441.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            59493..59666
                     /locus_tag="VUZ44_000473"
     CDS             59493..59666
                     /locus_tag="VUZ44_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU0319442.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFGGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(59659..60505)
                     /locus_tag="VUZ44_000474"
                     /pseudo
     CDS             complement(59659..60505)
                     /locus_tag="VUZ44_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            60756..62201
                     /gene="cps4A"
                     /locus_tag="VUZ44_000475"
     CDS             60756..62201
                     /gene="cps4A"
                     /locus_tag="VUZ44_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU0319443.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILASSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            62203..62934
                     /gene="cps4B"
                     /locus_tag="VUZ44_000476"
     CDS             62203..62934
                     /gene="cps4B"
                     /locus_tag="VUZ44_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEU0319444.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLIIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDKGCYT
                     QVNSSHILKSKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            62943..63635
                     /locus_tag="VUZ44_000477"
     CDS             62943..63635
                     /locus_tag="VUZ44_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEU0319445.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKRRLMILLVALVTGAGAFAYSTFVV
                     KPEYTSTTRIYVVNRNQEDKPGLTNQDLQAGTYLVKDYREIILSHDVLEKVATNLKLD
                     MPARALASKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFSFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLRIP
                     LLGLVPDLDKMK"
     gene            63645..64334
                     /locus_tag="VUZ44_000478"
     CDS             63645..64334
                     /locus_tag="VUZ44_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU0319446.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDNLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMSGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            64350..65717
                     /locus_tag="VUZ44_000479"
     CDS             64350..65717
                     /locus_tag="VUZ44_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU0319447.1"
                     /translation="MNGKIVKSSLVIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQAFFKRGYLIELVQTLKYILFFALAIGISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDATVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSVVLVPLIRKDGGSAIFAQTRIGKNGRYFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            65749..66921
                     /locus_tag="VUZ44_000480"
     CDS             65749..66921
                     /locus_tag="VUZ44_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEU0319448.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVTCMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELAKENKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDISELDEKSSQRIADAFTWEKIVSDYEEVFKG"
     gene            66925..68082
                     /locus_tag="VUZ44_000481"
     CDS             66925..68082
                     /locus_tag="VUZ44_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU0319449.1"
                     /translation="MKRILYLHAGAEMYGADKVLLELIKGLDSKEFETHVILPNDGVL
                     VEALRQVGAQVSVLDYPILRRKYFNPKGIFEYLKSYHRYSQKIAQYVRENGIVLVHNN
                     TTAVLEGIYLKRKVKLPLIWHVHEIIVKPKAISDFINFLMGRYANKIVTVSQAVASHV
                     NQSPFIKEGQVQVIYNGVDNAVYHPMPASTVREQFSIPEEALVIGMVGRVNAWKGQGD
                     FLEAVTPILEQNPNAIAFLAGSAFAGEEWRVEELESKIAKSSVVSQIKRIDYYEHTTE
                     LYNMFDIFVLPSTNPDPLPTVVLEAMACGKPVVGYRHGGVCEMVDEGTNGLLATPNQP
                     AELSKVIQELVENPEKRNQFGQASVERQRELFSLDSYIKNFSELYKTDRKD"
     gene            68085..69083
                     /locus_tag="VUZ44_000482"
     CDS             68085..69083
                     /locus_tag="VUZ44_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide phosphotransferase WcwK"
                     /protein_id="HEU0319450.1"
                     /translation="MNKIDFVVTWVDGNDPVWKEKKSRYDGSVSTSKQSMNSVKAYRE
                     WGTFKYWFRGVERFAPWVNKVYLVTDQQRPSWLDINSEKLVLVDHTEIICNDCLPVFS
                     ANPIESNIHRIPGLSEHFVFFNDDMYLTAPVEPTDFFSEDGLPKYNTALSPIIPERYG
                     TGNFQINDMEIVTSYFSRNEILKNGQFFDPKQGLKSIVKSLLYRNSQFICGFWESHLP
                     YPLLKSTMDLIWEKEKAVLGRTSASRFRNPSDTNVWLFKYWQIASGQYAVGNPKLGRL
                     FSLDNAGPDFWNLLNSGKYKIMCINDVYDIKDEEKVMQEFIAAMKNLLPDKSTFEL"
     gene            69099..70076
                     /locus_tag="VUZ44_000483"
     CDS             69099..70076
                     /locus_tag="VUZ44_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009731846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0319451.1"
                     /translation="MPSVCALVVTYNRSKYLQKALEGILNQQQEISGILIYNNNATDN
                     TEEILMKFGYVDSKGDKIKENYLYSTEKDGKHFYYYHNDENLGGAGGFANGIRLISEL
                     DYDYVWIMDDDVYPEPNCLSEIMKQMSVQNVQVGIPNRTDENFDDRAIIGFDFDDYHK
                     FWTEMRKTVTYGPFDEEAIKVVDMPFEGPVVEMALLRKVGIPDSGFFIEYDDSDFAQR
                     LQQYSDIIFATKAQLHRQLAVKVDPSEVKKVEPYNWRNYYKIRNNIIFDKRYGKNWKV
                     RQLSPLILIAHHIVIAIRHQHLKHNLPIIWKGFWDGVFQRMGKRVDPNY"
     gene            70089..71117
                     /locus_tag="VUZ44_000484"
     CDS             70089..71117
                     /locus_tag="VUZ44_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0319452.1"
                     /translation="MSDLLLSFIMPTYNSAEYLADTMDSLVASIGDYNHLVEIICVDD
                     GSWDNTVTILEGYKSIYDNLIIIRNEHGGVSQARNTALDIVSGKYISFVDSDDLYEKD
                     FLNTFISLDKNFDFLFTDVGGLKDEISFQEINEKEKLKIFKNNFNLGEYTIHPGIAGK
                     FFRTSLINDIQLRFNTQLSFAEDILFNFTLLTASRHVILSPVNFYHVNGTHSLMYYNE
                     KNLKGQIVFVDRIRQILKGYSESSEIVLIENFIILKAMTVYIDRYFGPLWLNGTYSLN
                     EASKLMKSTIEDNDFSKAFNSNRLDYSIGNRYVVFRKLLRFRQYKLCLLYNRIMDKIK
                     GYERFRKQ"
     gene            71537..72334
                     /locus_tag="VUZ44_000485"
     CDS             71537..72334
                     /locus_tag="VUZ44_000485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319453.1"
                     /translation="MSYNYAGLNIAPGIIEERGVNWTRYGAVRLQALFLDGYVLAYLL
                     CKLLISDSKNKVSYSLLLLITLFYEGVIYASRSQLIGFSIMFIAIYLLKNKNLLNKLL
                     SFLSLSLASFAILLSPYYEKFIDSFSVSNSDYGAGTMVRIVGRRYYQEIWNQNKLLGF
                     GPISDGNIFAGWKYYLSDLGIIRMLYQFGIIGFIICLLPILYGCLVGFKNRLHFKGML
                     LFCLSLFVLVTSFASQNLYDYNRIMLLPLLLGLANAVSSTQADKDMV"
     gene            72331..73755
                     /locus_tag="VUZ44_000486"
     CDS             72331..73755
                     /locus_tag="VUZ44_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEU0319454.1"
                     /translation="MKVLKNYAYNLSYQLLLIILPVITTPYITRVFSSDDLGTYGYFN
                     SIVTYFILLATLGVANYGTKEISGHRKEIRRNFWGIYTLQLGATILSGTLYAILCLSL
                     PSMQDSVAYILGFSLLSKGLDISWLFQGLEDFRKIIVRNITVKLVGVISIFLFVKSAK
                     DLYLYVFLLTIFELLGQLSMWVPAREFIGKPHIDINHAKKHLKPVILLFLPQIAISLY
                     VTLDRTMLGALASKTDVGIYDQALKLVNILLTLVTSLGSVMLPRVSSLLSQSDYKSVK
                     KMYQMSFLIYNSVIFPIIAGMLIVNDDFVQFFLGRDFQDARYAIAIMMFRMFFIGWTN
                     IMGIQILIPHNKNKEFMISTTVPAIVSVGLNLIFLPNLGFIGAAIVSVLTEALVWGIQ
                     LHFTWSYLKEVPIIGSMIKIVIASGIMYAFLVSMKSVVHVSPAINVALYALLGGVIYV
                     ALILLFKVVNLKELKQELLKNREI"
     gene            73757..74857
                     /gene="glf"
                     /locus_tag="VUZ44_000487"
     CDS             73757..74857
                     /gene="glf"
                     /locus_tag="VUZ44_000487"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEU0319455.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTADTKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEVSAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQPKTVITREYPADWKRGDEPYYPINDEKNNAMFAKYQEEASKNDK
                     VIFCGRLADYKYYDMHVVIERALSVVEEEFSN"
     gene            74885..75754
                     /gene="rfbA"
                     /locus_tag="VUZ44_000488"
     CDS             74885..75754
                     /gene="rfbA"
                     /locus_tag="VUZ44_000488"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEU0319456.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFIIGEKFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAQKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PKDPRSNYAVTGLYFYDNDVVEIAKGIKPSARGELEITDINKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLELAQPLKKN
                     EYGRYLLRLIGEV"
     gene            75755..76351
                     /locus_tag="VUZ44_000489"
     CDS             75755..76351
                     /locus_tag="VUZ44_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEU0319457.1"
                     /translation="MTDNFFGKTLAVRKIDAISGMLEFDIPVHGDNRGWFKENFQKEK
                     MVPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADNGKVLGTWVDLREG
                     ETFGNIYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYS
                     DPELGIEWENLEEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            76361..77410
                     /gene="rfbB"
                     /locus_tag="VUZ44_000490"
     CDS             76361..77410
                     /gene="rfbB"
                     /locus_tag="VUZ44_000490"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEU0319458.1"
                     /translation="MTKYKNIIVTGGAGFIGSNFVHYVYNNFPDVYVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDLRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQTAD
                     AYDHVTDRAGHDLRYAIDASKLCDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            77476..78327
                     /gene="rfbD"
                     /locus_tag="VUZ44_000491"
     CDS             77476..78327
                     /gene="rfbD"
                     /locus_tag="VUZ44_000491"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEU0319459.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATKDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            78390..79285
                     /gene="glf"
                     /locus_tag="VUZ44_000492"
                     /pseudo
     CDS             78390..79285
                     /gene="glf"
                     /locus_tag="VUZ44_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272499.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            79351..80409
                     /locus_tag="VUZ44_000493"
     CDS             79351..80409
                     /locus_tag="VUZ44_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEU0319460.1"
                     /translation="MKKIKEYEILKVIAIILVVVGHSTYYNIYTGYGGIDYQQYINNH
                     LSLAVYKLLSKLTEIIYYFHMPLFMAISGAFFSIQVKNNRWHGIGSLLTNKFRRLMIP
                     FLVFTLVYTIPIKYISNYFDGISFWKAVSGQLFLFGNSHLWYLYALFIVFIVGFYILK
                     KRTLFYVYLLLYILHILSYSVHLTLVSAPLQYLFWFSMGFLFEFKREQYNHYLKNNKW
                     LSFLLVLLFIACVALKFVLKDNHEVLNRIIMDLAAVLGSLICYNISYYLSDKRELTEN
                     RLFNVILINGLGIYIFSDTLNYLILNISYSISNRFMFTSFGILALFLIRIFFTLFIGL
                     GLTLLFKKIFKKHSWLVN"
BASE COUNT        24868 a        13562 c        16838 g        25295 t
ORIGIN      
        1 aaaaagttgg aagaagcttc caacttttaa aataggtttc tattagatta gtgggtgaag
       61 tcgagtacca tacgtccttg gatttggcct ttttccattt cgtcgaaaat ggcaacagca
      121 tcttctactg gacgtttttg aacaactggg actaccagac cttctgcacc aaattggaag
      181 gcttcttcta agtctttacg agttccgaca agagaaccga tgacttggat tccatcgagg
      241 actgttttaa cgatgctgag ttccatcatt tcagaaggaa gaccaacagc gacgacgcga
      301 ccaccagcac gaatggagtc aacagcctgg ttgaaggcaa ctttagacac agcagttacg
      361 acagctgaat gagctcctcc atcagttttt tctttaatga gtccagctac atcttcaact
      421 tcgaggccgt taatcacaat gtcagcgcct acttcttttg caagggcaag tttgtcattg
      481 ttgatatcga ctgcgataac atgagcattg aatacttttt tagcgtattg aacagcgagg
      541 ttaccaagtc caccagcacc gtaaagaaca acccattggc ctggttcaac ttttgcttct
      601 ttgatagctt tataggttgt tactccagca catgtgatag aagaagcttg ggctggatca
      661 agtccgtcag gaactttgac agcatagtca gcagttacga tacattgttc agccatacca
      721 ccgtctactg agtagccagc atttttcact gtacggcaaa gggtttcgcg accagttgta
      781 cagtattcgc aagtgccaca tccttcaaag aaccaagcaa cgctgacgcg gtcaccgact
      841 ttaaggcttt tcacatctgg agcaatctct ttaacgatac cgataccttc gtgcccaaga
      901 acacgtcctg ggacttgacc aaagtcacca tgagcaacgt ggaggtcggt gtggcaaaca
      961 ccacagtatt caacttctac aagtgcttcc ccagtttcaa gtggacggag tactttttct
     1021 tcaatagcaa caccagtgct ttctggattt acaacaacag ctttcatagc tatcctcctt
     1081 gatattgacc gagaacaggg acaacgggac tggattgatt ttttgtcaac agagtcgagt
     1141 gtgacgagct ctcttgtatt tatatgtgaa gtatatcaca aaagaaagcc ttttccaagg
     1201 ttttggagac aaaaagtaga acaatcgatt aactggttga tgagactgtg aaaagagcac
     1261 aaagaccagc ttgcaagctg gtcatactct tcgaaaatct cttcaaacca cgtcagcttc
     1321 atctacaacc tcaaagcagt gctttgagca acctacggct agcttcctag tttgctcttt
     1381 gattctcatt gagtatcagt ataggttata agaataagtc ttgtagggtt ttggcaaccc
     1441 catcttggtc gttggtaagg gaaatttgct catctgcata agggagtagc tctggattgg
     1501 catttttcat ggcataaccc ttcccagcaa aagcgagcat ttcggtatca ttgtgttcat
     1561 ctccaaaggc aatcaaatct tttttgtcac gattcattat cttgagcaag tagtccaaag
     1621 caaaggcctt gttgacacct tttggggtac attcaaggat attgagcgga cctccccagg
     1681 tattgataga aagttgatgc tggtagaagg cgttcatttc ttttgccaag gcatatttgt
     1741 cactggctct ggtctgcaag aggatacagt tagggtcctt ggtcaccaat tcaggctgga
     1801 attgatcttc aggctggaaa gcttctacac caaatagttt gggattggca atttcttcat
     1861 tgggatttgt aatgtagaat tttttacgat attctccagc gataaaatcg gcttgaatgt
     1921 cctctgaacg ttgaaccata tctagcagat attttttgtc tacagtcaaa cacttttcaa
     1981 aatcccaaac ttggtctggt aaatgagtaa gggatccgtt gaagttaatc ataggagtgt
     2041 ctaagcccag ttcacggtaa aaatcttttg acatacggta agggcgacct gtcgtaataa
     2101 taacctgatg gcctttttca gcaacttttt tgatggttct tttggtaaag tcagaaattt
     2161 gactgtctga gttgagcagg gttccatcca ggtcaactgc aataattttt ttcgtcatat
     2221 ggacctttct agtgtgtttt cagataagat gtcttctatt ataacagaaa gcaggcagaa
     2281 aagcagattc caaacaaaaa atgaaattgg attaatttct taaacaaatc aaacaaagac
     2341 attgaaaaag tgaatgataa atgatataat tctattattg ttcgtaaaaa ttaaaaggag
     2401 attgatgatg gacaaattat ttaaactaaa agagaacggt acagacgttc gtacagaggt
     2461 tctcgctggt ttaacaactt tctttgcaat gagctatatt ctctttgtaa acccacaaat
     2521 actttcacaa acaggaatgc ctgctcaggg cgtcttccta gcgacgatta ttggtgcagt
     2581 agcgggtacc ttgatgatgg ctttttatgc taacttacct tatgcccaag cgccaggtat
     2641 gggactcaat gccttcttta cctttacagt tgtattcggg cttggttatt cttggcaaga
     2701 agccctagct atggtcttca tctgtgggat tatttcattg attattacct tgacaaatgt
     2761 tcgtaaaatg atcattgaat cgattcccaa tgctcttcgc tcagctattt cagctggtat
     2821 cggtgtcttc cttgcctatg tagggattaa gaatgctgga cttttgaaat tcacgattga
     2881 tccaggcaac tatactgttg taggagaagg ggctgacaaa gctcaagcaa cgattgcagc
     2941 aaactcttca gcagttccag gattggtcag ctttaataat ccagctgttt tagtggctct
     3001 tgcaggactt gccattacta tcttctttgt catcaaaggg attaaagggg gaattattct
     3061 ctctatcttg acaacaactg ttcttgctat tgcagttggt ttggttgatt tgtctagtat
     3121 cgattttgct aataaccatg ttggtgcagc ttttgaagat ttgaagacaa tctttggtgc
     3181 agctcttggt tcagaaggat tgggagcttt ggtttcagat acagctcgct tgcctgaaac
     3241 tctgatggcc attcttgcct tctcattgac agatattttt gacacaattg gtaccttgat
     3301 cggtacaggt gaaaaagttg gtattgtagc gacaaatggt gaaaatcacc aatcagccaa
     3361 attggataag gctctttact ctgatttgat tggaacgaca gtcggtgcca ttgcaggtac
     3421 ttcaaacgta acgacttatg ttgagtctgc tgctggtatc ggtgcaggtg gacgtactgg
     3481 tttgacagcc ttggttgtag ctatctgttt tgcgatttca agcttcttta gcccacttct
     3541 agcgatcgta ccaacagcgg ctacagctcc aatcttgatt atcgttggga ttatgatgct
     3601 tggtagcttg aaaaatatcc attgggatga tatgtctgaa gcagttcctg ccttcttcac
     3661 atctatcttt atgggattca gctactctat cactcaaggg attgcagttg gtttcttgac
     3721 ttacactttg actaagcttg tcaaaggtca agttaaagat gttcatgcca tgatttggat
     3781 tttggatgcc ttgtttatcc ttaactacat cagcatggcc ttataataga atgacccagg
     3841 gggatttccc ccctttttta atacaaagga gataggtgat gaaagagaaa aatatgtgga
     3901 aagaattgtt gaatcgtgca ggctggattt tggtcttttt acttgccgtc cttttatatc
     3961 aggttcccct agtggttacc tctattttga ctttaaaaga agtagccctg ctacagtcag
     4021 ggctgatagt tgctggcctt tcaattgtgg ttctggctct atttattatg ggagctcgta
     4081 aaaccaagtt agctagtttt aatttttctt tttttagagc taaagatttg gcacgtttgg
     4141 gcttgagtta tttagttatt gtcgggtcaa atatacttgg ttctatcttg ttgcaactgt
     4201 caaatgagac gacaacagct aaccagtctc agattaacga tatggttcaa aatagttcgt
     4261 tgatttccag tttcttcttg ctagccttgc ttgctccgat ttgtgaggaa atcttgtgcc
     4321 gtgggattgt tcctaaaaag attttccgag gcaaggagaa cttgggattt gtagtcggta
     4381 cgattgtgtt tgctttattg catcaaccaa gtaatttacc ttctttattg atttatggag
     4441 gtatgtcgac agttctatct tggacagcct acaagaccca acgtttggaa atgtcgatct
     4501 tacttcacat gattgttaat gggattgctt tctgtttgtt ggcttttgtg gtgattatga
     4561 gtcggacatt aggaatttct gtttaaaagt ttttatgtag gaaccgacct ctttctacta
     4621 gggaaagatg aatgcaatcg tgtccatctt tttcttttta tggtaaaata gaaaaataat
     4681 atgatgaaaa tccttgaggg agtgaccgat atgtcaagta aagccaatca tgcaaagaca
     4741 gttatttgcg gaattatcaa tgtaacccca gactcctttt cggacggtgg tcaatttttt
     4801 gctcttgagc aggcgctcca gcaggctcgt aaattgatag cagaaggagc cagtatgctc
     4861 gatatcggcg gagaatcgac tcggccggga agtagctatg ttgagataga agaggaaatc
     4921 cagcgtgttg ttccagtgat caaagcgatt cgcaaggaaa gcgatgtcct tatttctatc
     4981 gatacttgga aaagtcaggt ggcagaggct gctttggctg cgggtgccaa tctagttaat
     5041 gatatcactg gtctcatggg tgatgaaaaa atggcccatg tggttgctaa agctggagcg
     5101 aaagtggtca tcatgtttaa cccagttatg gctcgacctc agcatcctag ttcgcttatc
     5161 ttccctcatt ttggttttgg tcaaaccttt acagaaaaag agttagctga ctttgaaaca
     5221 ttgccaatcg aagacttgat ggtggctttc tttgaacgag cactagcgag agcggcagaa
     5281 gctggtattg caccagaaaa tatcctgttg gatccaggaa ttggctttgg tctgaccaag
     5341 aaagaaaatc tcctcctttt acgggacctg gataaactac atcagaaggg ctatccaatc
     5401 tttctcggag tgtcgcgcaa gcgatttgtc atcaatatcc ttgaagaaag tgggtttgaa
     5461 gtcaatcctg agacagagct tggtttccga aatcgggaca cggcttcggc tcatgtaacc
     5521 agtatcgctg cgagacaggg tgtagaagtg gtgcgcgtgc atgacgtagc tagtcacagg
     5581 atggcagttg aaattgcctc tgccattcgt ctggctgatg aagcggaaaa tttagattta
     5641 aaacaatata aataagatga aagaaattga aaacaatcag tggattgcta actactggac
     5701 ggatcaaccg cattttggat tggaacgaat ggtggaactg ttagctttgc gtggcaatcc
     5761 ccatctcaaa ctcaaggtcc tccatatcgg agggactaac ggcaagggct cgactattgc
     5821 ttttttgaaa aagatgctag aaaagctagg gctgagagtt ggcgtgttta gctcgcccta
     5881 tttcattcat tacacagacc agattagcat caatggggaa tcgatctcag aagcgaggct
     5941 agaagctctc atggcagact atcagtcttt gctggaggga gaagcggtcg ccaatttaca
     6001 gggcacaacc gagtttgaga ttatcacagc cctggcctat gactactttg cctcagagca
     6061 agtagatgtg gccatcatgg aagttggcat gggtggactt ttggatagta ccaatgtctg
     6121 tcagcccatt ttgacaggaa ttacaactat tggcttggat catgtggctc tacttggtga
     6181 caccttggag gccatagcag agcagaaggc aggtattatc aaacaaggga tacccttggt
     6241 aacagggcgt attgctccag aagccttggc tgtgattgac cgcattgcgg aagggaaaga
     6301 tgcgccgaga cttgcctacg ggacagatta tcaggttcgt catcaagaaa gtgtggtgac
     6361 aggggaagtc tttgactata caagtgctgt cagacaaggt cgcttccaga ctagcctgct
     6421 tggtttgtac caaatagaga atgctgggat ggccatagct ttacttgata ctttttgtca
     6481 agaagatggt cgagagctag caagcaatga ttttcttggt caagccttgg aagaaacaag
     6541 ttggccaggg cgtttggaaa tcgtgtcaag agatcccttg atgattttgg atggagccca
     6601 caatccccat gctatcaagg ccttgttggt aaccttgcaa gaacgttttg cggattatca
     6661 taaggaaatc ctcttcactt gtatcaaaac caaggccttg gaggatatgt tggacttgct
     6721 gggagccatg ccagataccg agcttactct aacacatttt gcggatagtc gggcgacgga
     6781 tgaaagcgtg ctgaaagagg cagctaagtc tagaaatctc agctaccaag attggcatga
     6841 ttttctagag cagaatttga cagataaaaa agaagagaaa caaacagtta ggattgtcac
     6901 aggttccttg tatttcttga gccaagtgag ggcctatctg atggagagga agaacgagaa
     6961 tggatacaca aaagattgaa gcagctgtaa aaatgattat cgaggctgta ggagaggacg
     7021 ctaatcgcga gggcttgcag gaaacacctg ctcgtgtagc ccgtatgtat caagaaattt
     7081 tttcaggtct tggtcaaaca gcagaggaac atttgtcaaa atcctttgaa attattgacg
     7141 ataatatggt ggtagaaaag gatatctttt tccataccat gtgtgaacac cacttcttgc
     7201 cattttatgg tagagcgcac attgcctaca ttccagatgg tcgtgtggca ggcttgtcta
     7261 agctagcccg tacggttgaa gtttattcga aaaaaccaca aattcaagaa cgtttgaata
     7321 tcgaagtggc cgatgccttg atggactatc taggtgctaa aggagccttt gttgtcattg
     7381 aggcggaaca tatgtgtatg agtatgcgtg gtgttagaaa accaggcact gcaaccttga
     7441 cgacagtagc tcgtggtcta tttgaaacag ataaggacct ccgcgaccaa gcttatcgtt
     7501 taatggggct ataaaaagaa tccgcttcaa gcggattttt ctagaaagga atcattatgg
     7561 atcaactgca gattaaggat ttggaaatgt ttgcctatca tggtcttttt cctagtgaga
     7621 aagaattggg gcagaaattt gtcgtttcag ccatcctatc ctatgatatg accaaggcag
     7681 ctacagactt ggatttaaca gcctctgtcc attacggaga attgtgtcag cagtggacga
     7741 cttggtttca ggaaacgagt gaagatttga ttgaaacggt agcctataaa ctggtggaac
     7801 gtacctttga gtcttatcct cttgtccaag aaatgaagtt ggaactgaaa aaaccttggg
     7861 caccggtgca tttgtcacta gatacttgct cggtaaccat tcatcgccgc aagcaacgag
     7921 cctttatcgc cctaggaagc aatatgggag ataaacaagt aaacttgaag caagccattg
     7981 acaaactgcg agctcgtggc atccatattc tcaaagagtc cagtgtctta gagacggagc
     8041 cttggggtgg agtggagcag gatagctttg ccaatcaagt ggttgaggtg gaaacctggc
     8101 taccagcaca agacttgtta gaaaccttgt tagccattga gtcagagctg ggacgggtga
     8161 gagaagtgca ttggggacct cgtttgattg atttggactt gctctttgtg gaggaccaga
     8221 tcctttatac agacgacctc atattgcctc atccttacat agcggaacgc ctttttgtcc
     8281 ttgagtcctt acaggaaatt gcgcctcatt ttatccatcc gatattaaaa caaccgatcc
     8341 gcaacttgta tgatgctttg aaaaaataga aaaactctag ttttcagtta cttgcaactg
     8401 aaggctagag tttttaaaat aggtcatttt cttctgggag gaggatagtt tctctaccgt
     8461 ccatgtctaa aaccagtact cttgggggat aacgagggtc gaaaggatgg ttaaagtcaa
     8521 aatcaatggc tgtagggagg tgttgacttg aaaagtggaa ggtaatcttt ccttggttat
     8581 taagcaattg aaactcgagt tcttcttcca attcaaagac attttttaag aaatggtcga
     8641 tgatatacca aaaagagtca atgatgtcat caggcaagct ggtaacaatg ccaaaactag
     8701 cagatcgcat gtgggtattg gtaaaagcca tatctctgtc ccctttcttt tcccttatca
     8761 tacagcaaat aggattaaaa atcaagaaaa ggtgattttt tgaaaaggat tttagttaca
     8821 gggagaaata gggaaaaaat tcctaaaaat ctaccgaagt taataggtaa attcccaaat
     8881 taacttgatt atataacttt cagttacttt gagaagttac cgaaaaatat ttttcatatc
     8941 tattgacttt taggggtaaa atttggtatg atagtaggcg gtattgttta ccccatttga
     9001 aaggccccgg aaccttccaa atacttttcg atgggaagga acacccatca ccgtaaacaa
     9061 aaatcgaact atatatagga gaaatcatga acaaaacaac atttatggct aaaccaggcc
     9121 aagttgaacg taaatggtac gtagttgacg caactgatgt accacttgga cgtctttctg
     9181 cagtagttgc tagcgtactt cgcggaaaaa acaaaccaac atttacacca cacactgata
     9241 caggtgactt cgtgattgtt atcaatgctg aaaaagttaa attgactggt aaaaaagcaa
     9301 ctgataaaat ctactacact cactcaaacc acccaggtgg attgaaacaa atctctgcag
     9361 gtgaacttcg ttctaaaaat gcagtacgtt tgattgagaa atcagttaaa ggtatgcttc
     9421 cacacaatac acttggacgc gctcaaggta tgaagttgaa agtatttgtt ggagctgagc
     9481 acactcacgc tgcacaacaa ccagaagttc ttgacatttc aggacttatc taaggaaagg
     9541 aacaataaag tatgtcacaa gcacaatatg caggtactgg acgtcgtaaa aacgctgttg
     9601 cacgcgttcg ccttgttcca ggaactggta aaatcactgt taacaaaaaa gatgttgaag
     9661 agtacatccc acacgctgac cttcgtcttg tcatcaacca accattcgca gttacttcaa
     9721 ctgtaggttc atacgacgtt ttcgttaacg ttataggtgg tggatacgct ggtcaatcag
     9781 gagctatccg tcacggtatc gctcgtgccc ttcttcaagt agacccagac ttccgcgatt
     9841 cattgaaacg cgcaggactt cttacacgtg actcacgtaa agttgaacgt aagaaaccag
     9901 gtcttaagaa agctcgtaaa gcatcacaat ttagtaaacg ttaattcgaa agaattacta
     9961 tacttataca gagcaccttt cggggtgttc tttttttata ctttcttact aaattggtgc
    10021 aattgacaca gttgttgcga ctttagtcgc ttacaaatgt ggctgcaacc tgacatggtc
    10081 agttgcctca aaacgttaat caactcgatt atatcaacgt ttcgaagcac tcacaggttt
    10141 gccctatggg tgcttttttc tatactttct acaaaagttt gccctaaaat ttgccctaaa
    10201 ttttctctac ttgtttttaa gatgttggta ggcaacttgt ccagcagata atggaactat
    10261 gtttgaagta ttaacataag tcttcgttgt aattgtatcg ctatgagtta atgcttcaga
    10321 aatggcttct aagctcattc ctgctttttt agcaagtgtc gctcctgtat gtcgtaattt
    10381 atgaggtgta gcgtgtttta actttgggtg tcgtcttttt acggagttca ttttgttatt
    10441 gagataatca acgtgtagag ggctatttac attacctttc gtatctatat aggtaaagac
    10501 tagttgatcg gatgtttgca ttataccaaa tttcgctaac tcatatttct gttgtttttt
    10561 ccattctgaa agaagtgata caaggtaact aggaattgaa aaaatcgttt tcttatttcc
    10621 ttttgttgac tttacattct tatatttgtc aagtgcatgc cttaagtcaa tttgagcatt
    10681 tgccaagtct atgtttttcc aatgtaaagc ataggattct gattttctat cgctcaaaat
    10741 aaaggttgta aagaatagga cataatcttt tagtgataat ttatcgttct ccaaatcttc
    10801 tctaaaagca tcaaaccaat cttgtaattc ttcactagat agatacaagt cttcctcatt
    10861 tttggattct tggagtttta gctttttggt agctttaatt cgtttaattg tcttggataa
    10921 tcgatttgat tctatgtact ccaattcctc agcccaatcg aaaattgagt ttacatagct
    10981 tcgaataact ttgaaattag catactcttc agctttagca gtcattaagt ttagtacgac
    11041 ttgcttattc tgattcagaa aattgattga ataattaccg aacattggta aaatatgctt
    11101 tctgaaaaca gtttcagtat tatcgatagt agcctgtgtt ggaggcttag ttgttgaagt
    11161 tgtttgacca gctttgtatg aatcccacca aatattatta aagaactcag agaaaagaat
    11221 atcactagtt ttagggagtg ggatatcctc tccattttca agttgatgta tctttgttag
    11281 aatttctaat tcagcttctt tagcctcctt tcttgtttta tagcgtttaa caaagtgatt
    11341 tcctttaatc cccattttag gtcggatttc tttaggtata tacactttaa gattgtaagt
    11401 gttactattt gtttttgtaa ctgacatgat gttttccttt tacgagtcag gatatatcat
    11461 tagagatatt atagcatagc ttttctacaa agccatttat caatctcatt tttattgaaa
    11521 cggacagtct taccaatttt aataacgggt agcccctttt gtatccagcc atctaatgta
    11581 ttgttagata tccctagata tttgcaagtt tgccccttgt taaggtaagg actatctaaa
    11641 cctaaatctt ctttgaaatg agaaatttca ttttgcaaga gattagtgat catcgactgt
    11701 atttcttgaa cttgttctgt tggtagaata acttgcattt tttccttact ccttatttaa
    11761 ctttattttt ttgtatttta ctttattgtc aattaagtgt ccttttcgaa atactttgct
    11821 aatatagttg ctttcatata ggatatcttc attcttaaca aggttatcta aggattcact
    11881 tgtaaataat tttatttctt caggcttttg taaattacga gaagaataaa aagccttctt
    11941 tcctagactc tctaataatt cctgtcctat gcctttttcc atatattttg caacataacg
    12001 accagcatta gaagaatcat ctaagtcatt tagtttgttt atccgaactg cacctaaccc
    12061 ccaaattgtt agtaattctt tatgagggat aaaaggaaat gaaaaaagga gaatgtgtgc
    12121 atgccacgct cccctttttt gtcgttctaa tactgcaata tatttaataa gtcttttttt
    12181 ggaatggtat atgtgatagt ttaaacgttt aataaattta tcaaaaagta aattaaattc
    12241 atatctgttt tgtatatttt ctttggttgt aagggtaagg aaactagttc tgtcatcaaa
    12301 atttgtatct attaggcgtt gaagtttcca tttagaattt ttacgagtgt tagaaattct
    12361 ttttattcgt tcatcttgtt cagcagttgt gagttcttca aaagttctac gtttcttctt
    12421 ttcttttagt gaaatgtgtt cttcatcaat ttgagtagta tcatttgaaa aaattggaga
    12481 ttcgtattcc catatttcaa ggtacgaaga agttcggata attttgcgat tgtaactcac
    12541 aaaatcatct ccttttctcg taatgtttgc ttatataata aataaactag gagaagcaaa
    12601 gctcctccat acttctatca tgtgtttcta agcatcgcta tgctaaacac gcttccagct
    12661 tgccgacttc cagtcggcag tttcgcttag tcacatgatg agaagtagta gttaaatttg
    12721 aggtttaggt aattgtttta atgtttggtc tgtagcccag tcagttgaaa tgatttcaag
    12781 atgtccttgg tcataaacga gcaaatctcc gttaccaata aattgatatt tattatcttt
    12841 gtcaatatat aatgaaaaag tatctatacc aataacattt ttagaaatat cgatagattc
    12901 tttaggggta tgtccaacaa tttgtttagg gtagttgtta ttagggatta gctctagttc
    12961 tctaaaatga gcccataaag gagaaccagc catatctcct cctccacgca tatatcctac
    13021 tgcattagca aggatttcta attcttcttc atattcttca gtaaaaggtt taaagtgcca
    13081 ttcttttggg tcaaatagca aattgaaacc agcatggcta actaaataat catctagttg
    13141 ataagctact tgtaaattca aatcttgtaa taattgttga actgcgaaaa agacctctag
    13201 attttgaatt gagaaaggaa cttgttctcc aagtaaataa taaacatcgt gattgcccat
    13261 aaggttaata acttctattg aatttaattc tttttctatt ttccaatcgt atagaaaagt
    13321 gagatctttg gcatatagtt ggatattgtt agtttgtcca tgtaaatcaa cataatcacc
    13381 aagaaaaatg attcttttaa tattatgtgt ttgtataatc ttgtcaacaa taggtaaaat
    13441 tagttgagat tttaaatgta agtcgccaat taataatgtc ttcatataga ttcccctctt
    13501 tatttttgat attagtctaa gaatagagtt aaattctgcc aatttttttt aggatgttat
    13561 ttaatattga taggattttg taactgtatc atagcagata acaggtattg ttttgctatt
    13621 ctttacatct ccatcgataa agtaatgact tttactatca tggtaaatct taccttggta
    13681 agctttatct ttagctactt cccaagaagc aacatgacca gaaacaatat ctttaaaaaa
    13741 ttcaccagtg gtaagaggaa atttatttgt aaacatctct gaactcgtta ggtctttcca
    13801 aagcttgcca gcttcttcat caataccagc atgaacaaaa atttgggtat cagtttcata
    13861 atagcgttta tccctatatc gttttttaaa ccagtttatg aatgggttga acttgatatt
    13921 atttttaatt tcatttctaa cacctgcttc aaagttgtta acattagatt ttaaaatata
    13981 ggtcaattcc tctggagaga agaaactttt tattgtttcc gaaaatgaag aagaagtagg
    14041 attttctaaa atcaaccaat cataaaacca ttcttcgtga tttcctaaaa gagtaataat
    14101 ttgattagga tgaagttcct caagttcaat tattttggaa ataacttgaa aagattgatg
    14161 tccattgtca atatagtctc caagtaagat aagtttactt tgtttatcag ataaatctat
    14221 tttattgaga gatttaataa actcattgta gtgcccatgt atatcagata ttgcaaaaag
    14281 tttagccata aatagtatca ccgaattatt tagaaatagg gactacatcg ttacaagaaa
    14341 accataaatt tccgttaaat tgtccaactg ttaaattaga taatttaatg gggcatgttt
    14401 ttttatctga taataattga ggagtagccg taggagataa cgtattaact tttatctgga
    14461 tcatttccat aaagaaatca gaatcctcat cttgaattga aacattaaga cgtagtgcta
    14521 caggtttatt tgtttctctg tccaaaactt ctgtatatcc ttttactgcc acgaatttat
    14581 ttcccaataa ttctggttta agaaaatcgt taattttcat aataatacct cgtttctttt
    14641 tgtcatcgct taagcgatga ggaatagata tttttgctga aaatctattg aatttaagca
    14701 aaaatatcta ttgaaattat tttgactttg ttacgtataa ttgtagttct tttataaaat
    14761 cgaattgcgt tgtatcaaga taaggacttt cccaatattg agctttttct ttccctgagc
    14821 cctgcatata aagatatcct gctccttttt cttcaataga tttaaactta tcaggtgtgg
    14881 ccgtgccaaa taccatgcgg tatccctcta ttgagtttgc tcctaaagct attctcagtc
    14941 ctaaattatc tctaagatca gtgtttagag tttcagctct catttgttga gcagatataa
    15001 gaataaatac tcctgcttgt cgccctagta ggataatttg tttgataccg tccattactt
    15061 cggtgataac ttctttagat tttttatctg ttgctgaagc ttgaaatgct cccatttcat
    15121 caaatataag ccatactggt ttaaagccat ggtcggcaaa atttgatccg taatgaaagt
    15181 tatcacgcat ggtttgatat cgtgcctgca tttgttcaac tactaaacgt acaatacgag
    15241 caatactatt gggggttgta gctacatatt tatcgcttaa ataatgagat aaactaccta
    15301 aatcactgtt cttaggatct gcaatatata gtgttgaatt tcttttaaga agttcaataa
    15361 ttaagaaaga tataaatata gattttccgc tacctgtacc acctgaaact aaaatatgag
    15421 ggcattttat aggattataa gttatatcat atcctaagtc tatatcaaga ctatctatct
    15481 cttttttatg atcatggggt gataatatta gtctatcagg tttcttgtaa taaaagtgat
    15541 attccacaat attaggatga gtaatttttt cttctagttc aagttctaga actccagcta
    15601 atacatcgtc aagtgtctga acctttttac taaattcgtc acctctgata agcgctttaa
    15661 tgataatacg accgttttga ttatctaatt catattttaa aatcgcactt ctaataattt
    15721 cttcgtaacc tgaattatcc ttttccgaag tgtagagatg atttgtatat aaaccaaata
    15781 gtaagctttc cctgataatt aaatcaaaat ctagttcgta tctaaaatct tttaatttat
    15841 tatttatttt atagattgct agaacaccaa agacaataca taagatttga ataaaagcag
    15901 gagctctaat acttactatt aaacctaata aaacaaagat agaaaagata attattatca
    15961 gatgtaacaa ttttaaacgt gaacttgtaa taaaataatt tctttttaag ttagcttctt
    16021 tttttagttt aaacataaac aacaaacctc tttaagtggt aaaacaacta tacaattatt
    16081 tatatagaga acctaagcaa accctgctta ggttattgtt gtgtcttcca ataggaatat
    16141 acaacaagtt taatgatgta actaagcctt ggtaatctag tagcaccatc ttctttcatt
    16201 aaatgatatc gaaattcatc aagaccattt agaacatttt catctaaata gagtctagga
    16261 gttacggatg tttctagact aggattgaca tttttgatgt ctttttccat ttcttgacgt
    16321 agtttttgcc attcatcaat ggagtaatgt tttgtatttc tatatgattc ttcaatgaca
    16381 cttccgatag aagcttttaa aactatattg aaagagacac catttaattc atcgtaatga
    16441 tttgatagaa gtgtttgttc taatgtactt agaaaattat tctgacttag ttctttgatt
    16501 ttacgttctt tattttgaat aagttcatct atccatactt tggcttcata tgcgagacga
    16561 acacttttat atactctgac cacaaatcct cctttttaaa attcattaga aaattttatt
    16621 ttatccatat tttcaatttc tttatagaaa ttgaaatctt tttgatctaa ttgatcacaa
    16681 atttgtttaa tgataaattt accacgttct tcaattcgtt cattgacttt tttgaggaaa
    16741 atttgaaaat tctcttcttt tgtgggcctg atggcattat tattatgatt atcccaaaat
    16801 aactctacac tataatcaga attaacatat ggttgaaggt ggtacatttt tatgaagttt
    16861 tcccatgctt caggagatag aatgtttaaa aattcttgaa gtgatattaa agtgatatcc
    16921 cagtaatcac ctagtctaag acctctacca caattcatcc aattaggaaa tactgtaaaa
    16981 tttccgattg tatgagttgt tcttgcaaat aatttaaagt tctctaaatt attttgaata
    17041 gtttcaaatt ttaaataatt ctgatgttca caaagaacag aaattgggat tttcttcttt
    17101 gttatgccta attttgttga ctcttcatca aaatttgaac tatttccaat ggcctcctta
    17161 aagatggtaa taaaggagtt cattgtttct cctctaatgg tactatcttg tgattcttgc
    17221 catcccaaac atttatatag aaagaatgca gctttatcac aatctatacc ctcattttca
    17281 gggagctgtc tgtattttaa aaaagcagta atactatcat tgggtagtgg agaaagtgag
    17341 tggtttttaa aatcccattc ccatggtttg atattatttt catcacaata tttcaaccaa
    17401 tcaataactt cttgatgttt cataagaatc ctcctgtttt tttgattgtt gtattaggac
    17461 aacttataca aattattata acactttaaa aaagaattgc aagagttttt ttaaaaaaac
    17521 tccaattttt taagctgtct attgtttcgt tgtttcccac ttgttaagtt aagtattaaa
    17581 aaattaatta aagactgatg tggaaaaaca taaatctcaa tttgagtaga aaaatgtcca
    17641 tgataaaacg cacaatatca agttttaccg aaatattatg cgttgttata attttaaatc
    17701 ttttcatcag ttgtactatt agtgaatgaa atctatatct ttaattatta atgttataat
    17761 aattaaagat tttatcagtt tcgtcgtccc attcatctgg tgttagctta tagtttttat
    17821 gagaatattt atcaagtatt gctattcctt gctttaaaat gtattctcct atgtacattt
    17881 cgatcatatt tctactttgg aatttgtgct ctaatccccc tatcccactt ccttttccgt
    17941 atgaacctac ttgtctaatt ccagttataa aaattaaaat ggcattttta ctccatttat
    18001 tacctaattt atttataata tttgcaccaa tatatttatt agatgttggc attccgtaat
    18061 catggcctgc gccgataact acaatatgcc catcttctgt aaattgtaca aataagcact
    18121 ccccaacttt agttgtaaag tctttttgtt tagatagatc cacatttaaa atgtgatatt
    18181 taatatttga tgcttcataa ccaggtagtt cacttaaagg ttttaagcaa gtttcgacgt
    18241 gttttctaac ctctaaatag tattcattga aacttttatc tattggatga tttttaaatg
    18301 tctcaatacc aatttttact cgttcttctc ggcttggttt ccatgttccc ataaaatcct
    18361 cccattgaaa atatataatc aattaaaatt ttttatattt atttttttct agtatttaca
    18421 gagtaaatat atgctaaata atttgcaaaa tctccctgac gttgtctatc atttgtgatt
    18481 tgatcaaacc aattagtatt ttttccgtca ttttcagaga aatatttaat aacttttaat
    18541 tgacttataa aagctttatg agtagatttt ctggaaatat cattttgctc tctctttggc
    18601 agtggaattg tttcagacct gactcgaagt tctgtatatt gcgctgctaa ttcgattaac
    18661 gttgtccagt tttcaagaaa atcaggatct tttgtattca aagagctcac tagattgtta
    18721 tatatttccc cagcttcttc aaaagttaat gcagttttat ctttcagaaa gtctgaataa
    18781 gtgtaaattt ccataaaggg cctccacaaa aaaaatattt tttgtctaaa tacgactata
    18841 cttttattat aattctatct aaaaataatg tcaaggattt tcgtaaaaaa attttaatta
    18901 gttttacaaa agtattgcgc aataggatgt taagttttga tatttgtagt ataattagta
    18961 ctgactgatt tcatcaatta gggcaaattt ctgagatatc tgactcgtat ttttttattg
    19021 gataaaaaat ttgccctatt tgaatgaaat tatttaaaaa tagataaaat ttaattgata
    19081 attgattgta aaaaagtccg tgtttataac tatttgtgat attttaattt aatagttagc
    19141 caaaccaggt cttaagaaag ctcgtaaagc atcacaattt agtaaacgtt aattcgaaag
    19201 aattactata cttatacaga gcacctttcg gggtgttctt ttttatactt tcttactaaa
    19261 ttggtgcaat tgacacagtt gttgcgactt tagtcgctta caaatgtggc tgcaacctga
    19321 caaggtcagt tgcctcaaaa cgttaatcaa tacgattata tcaacgtttc aaagcactca
    19381 aaagtttacc ttatgggtgc ttttttcgtg tttttttgaa aagtttacct tatttttata
    19441 gtaatgtgaa ataagaatag gacaaactga ggatagtcaa atcgaattct aacaatgttt
    19501 tagaagtaga ggtgtactat tctagtttca atctactata ttatggataa tgcaagattc
    19561 catagaatgg gtaagttaga actcttgtgt gaagagtttg ggcataaact tttacctctt
    19621 cctccctact cacctgagta caatcctatt gagaaaacat gggctctttt gtcctgctct
    19681 tgtttcaatt gactataaat cgctataaga aaaaatcatt ttattggtat aaagaagtga
    19741 ttgaaagtaa tggcgaaacg ttagataatt agttcataaa aaacaagttt agatcctcat
    19801 ctaaacttgt ttttttaaaa ttgaaggatg attttgaagg atataagatg acattgacta
    19861 ttcatgtata ttataaaggt gatggagata gtgcaataaa gtttgcaaga gaaatgcttg
    19921 atagtggcct tgttgaagaa attagaaatc aaaaaggtaa cttgaaatac gaatattttt
    19981 taccaattga aaaagaggga actattctcc ttattgatca gtggataaat caagaagctt
    20041 tagatgaaca tcatcaatca aagacaatgc agaaaatctt agatttaaga aaaaaatatc
    20101 acttgcagat gcaagttgaa cgttatatag aagatgattc tgggatgcca gaaagcgata
    20161 agtcgtttat agacacaggg aattagaatt attgtgagag tttttgtagt ttgaaagtat
    20221 tgaaaatcgt aaagatatca ttacgagaat acaagaagat attgttctat ttccattaaa
    20281 aattacttct ttccttaaca ataaggaaaa agaatgcgtt ttcatctttt ggtttgaggt
    20341 ttataataag agtatcaaag tcaggaggaa aaaagatgac tacttttaaa gatggatttt
    20401 tatggggtgg tgctgttgct gctcatcaac ttgaaggtgg atggcaagaa ggtggcaagg
    20461 gaattagtgt tgctgatgtt atgactgctg gtcgtcatgg agtagctcgt gaaattactt
    20521 cgggagtttt agagggtaaa tattatccaa atcatgaggc gatagatttt tatcatcgtt
    20581 ataaagaaga catagcactt tttgctgaaa tgggattcaa gtgcttccgt acctctattg
    20641 catggacgcg tatctttcca aaaggtgatg agttagagcc gaatgaagaa ggattacagt
    20701 tttatgataa tctttttgat gaatgcttaa agaatggtat tgaacctgtc atcactctat
    20761 ctcattttga aatgccttat cacttagtga ccgaatatgg tggttggaaa aataggaaat
    20821 tgattgattt ctttgctcgt tttgcagaag tcgtatttaa acgttacaaa gataaggtta
    20881 aatattggat gactttcaat gaaatcaata atcaagcgaa ttatcaggaa gattttgcac
    20941 catttactaa ctcaggtatt gtatatgagg aaggtgataa tagagaagca attatgtatc
    21001 aagcagcaca ttacgaatta gttgcttctg cacgagctgt aaaaattggt catgagatta
    21061 atccagattt tcaaataggt tgtatgattg cgatgtgtcc aatttatcca gctacttgca
    21121 atcctaagga tatcttaatg gcaatgaaag ctatgcagaa gcgttattat tttgctgatg
    21181 tgcatgtttt aggtaaatat cctgagcata ttttcaagta ttgggaacga aaaggtattt
    21241 cagttgattt tgctgcccag gataaagaag atttacttgg tgggactgta gattacattg
    21301 atttcagtta ctatatgtcc tttgctatcg actctcatcg tgaaaataat ccttattttg
    21361 attatcttga aacagaagat ttagtgaaaa ataattatgt taaggcttct gaatgggagt
    21421 ggcaaattga tccagaaggt ttacgttatg cgttaaattg gtttacagac cactatcact
    21481 taccactctt tattgttgaa aatggttttg gagctataga tcaagttgca gcagatggta
    21541 tggtacatga tgattataga attgaatatc taggtgccca tattcgtgaa atgaaaaagg
    21601 ctgtagttga agatggtgtt gatttaatgg gttatactcc atggggatgt attgatttgg
    21661 tttcagctgg taccggtgaa atgcggaaac gttatggttt tatttatgta gataaagatg
    21721 acaatgggaa gggaagttat aatcgttccc cgaaaaaatc ttttggctgg tataaggaag
    21781 ttatttcatc taacggtgaa tcagtagaat atgctaaaca aactgagatt attctcagtt
    21841 tgtttagcat attgggatga catatgattg gaagtattgc agcaatttta acaacatttg
    21901 catttttacc acaagttttt cgtatagtta agacaaagga cacaggatct attgctctag
    21961 gtatgtatgt tatgcaagtt attgatattg cattgtggct tgctcatggt attcgtatag
    22021 gagacttgcc tttgatttta gcaaatagtg tttcatttct actctcagga ataattttat
    22081 tttataaatt gaagtataaa taattttttt ccatatcatt taggaaaatg agggaattgt
    22141 cattggaaac gctttatttt ataataaaaa tagataacag ataagtcaac ttagcacagc
    22201 tttgattgga tttaagaaaa ggagaaaata ttatggcaaa agctttaatt atttgtgcag
    22261 caggaatgtc ttcatcactt atggcacaga aaacaacaga gtttctaaaa ggaaaaggga
    22321 aagatattgt agttgatgct attagtgcta ctgaaggagg gaaagctatc gcagcagcag
    22381 cttttgattt gtatcttgtc agccctcaaa caaaaatgta ctttaagcaa tttgaagagg
    22441 ctggttctaa agcaggaaaa ccagttgtac aaatacctcc tcaagcctat attcctattc
    22501 caatgggaat tgaaaaaatg gctaatttga ttcttgagaa tatttgatga acacatgaaa
    22561 tgtcaataaa tatttaagtt aagataaatt gttttgagtt tgatataaat tgatttaagt
    22621 gtataatatg cttcaatata tgaaaacata cgttttagga gggaatgaat gtgttaaaca
    22681 ttaaagagaa agatatcctt caatttttaa taaaaaataa ggaacgtttt gttacaagca
    22741 aagaactggc agaatattta tcctgttcag atagaactgt ccgtaatgta ctgaaattaa
    22801 ttgagaagac aatgattatt caaggagtcc ggttgatttc aaaacaaggt caagggtatc
    22861 aaatattttt tgagaatcaa ggcgcttacc aggagtttag acaaacttat gaactggaag
    22921 aagactatac gaaaactgcg gtttcaaaag gtgatgatcg tttagtattt atcttaaata
    22981 aattattatt tgagcaagtt ccagttcttt ttgatgattt agctgatgaa ctttacgtta
    23041 gccgttcaac attatctcat gatttcagaa agatacgagt gatgttatca gagtataatt
    23101 tgtccattga gagtagggcg aataaaggag tttatgtctc aggcgaggaa cgtgataaac
    23161 gacgttttat cataaattat ttcctagaga atcaattttt taaaacaata cattgctatg
    23221 taaaatttaa cttttttgat caaactgttc cattagaaga atttgctaga attgttttgg
    23281 atgaatgcca agaggccaac ctaaaactat ctgattttgt actacagaac ttagtagttc
    23341 acatagcatt gtctgtgatt cgtttaaaat ccggatttga aataaaaaat atagactgtc
    23401 agatgactga tgatgcaaca gagagaaagg ttgcccaaag aattctttct aaagtaagag
    23461 aagtaacaaa tcaggaattt ccagttcagg aaatagacta cattactttg catttgttag
    23521 ctaagagtca acaatgtcaa aaaaatcaga agaatatttc tgaagaagtt ttaaaaaaat
    23581 ctttatttaa aacatttcag aatttaggat tagatgatat gtataacttt tcttcagatt
    23641 tccaactaat tgaaggattg ataactcatc taatgacact acaagtacgt ttagaaagcc
    23701 ggattacctt aaataaccct ttagtagatg aaattaaaca gaattatagt gatatattct
    23761 ttatgactag agaaattctt gcaaatatgg acaagttctt ggagtggaca atatcagatg
    23821 atgaagtagc atatgtaagt cttcactttt tagctgctat ggaacgtagc aaagagagta
    23881 ctaagtttaa tattcttgct atttgtgcaa caggatttgg tgcagcccaa atgttaagaa
    23941 atcgtttgga aacggagttt gggaagcgag tagaagttgt tgatgtaata ggctattatg
    24001 aattgaatca agaaaaactt aaaggaatag attttatagt gtcagctgtt gatttatcaa
    24061 atctatattt tcaaatccca gtttttaaag ttagtgtgtt tcttaagagt gatgagatgg
    24121 aaatgattag aaaagctatg gatcagatgc aagtttctag ttatgtacaa tcatcaaaga
    24181 ttaataaatt tgaaaacaac agctttagac agtattttag taaagaaaat tttttaatat
    24241 gtactgaatc agacaaggta aatttacttg aaaagatggt tgagagttta tctgttggtg
    24301 aatcaaatga gtttgaacaa tctttacttt atggaattaa acagcgcgaa gaattaagtt
    24361 cagttgtttt ttctgaaaaa attgcagttc cgcatcctat tcagcccttt ggtacagagg
    24421 gaaaggtttc ggttgcaatt tgtaaagatt cgttactctg ggataatcaa agttcacatg
    24481 tccagctagt atttcttcta tctccatcaa tatatgggaa cgaaggtttg gcaactgtga
    24541 ctaaaaagat agtctctctg acagagaatg atgaattgca aaatcagcta atatcttgca
    24601 ataactttga agattttatt aacatatttg agaagataaa ataggaggtt catatgaatc
    24661 aagaggaact gcaggttgca gcatttgaaa ttatcctgca ttcgggaaat gcaaggtcag
    24721 aaatacatga agcatttgca aaaatgagag aaggtagttt tgatgatgca gaaagtaaat
    24781 taaatcaatc aaatgagata attcttgaag cgcatcatgc acaaaccaaa ctcttgcaag
    24841 aatacgcaag tggagtggaa attaaaattg aaattatcat ggtacatgct caagatcatt
    24901 taatgaccac tatgacatta ttagaagtag caaaggaaat gttagctctt tataagaaag
    24961 ttaactaaat atgtgttgtt atataaggag gaaatgatat ggataaaaaa gaacgacaaa
    25021 agattgaaca acaacgtcga gagatggctc taactaatac tttttttaat cgatatcttc
    25081 ttctacgtta ttcaatagca ctcttctttt ttgggaatat ttattggctt ttgaatcagt
    25141 ttattagtcc ctcgcctatt attattttcc ccattatgct catagtattt tctattttag
    25201 caactattga acaatttaaa ctttatggaa ataggaaaga aaagtcggga ataacactaa
    25261 tgtttgttag aatacaaata cttatttcaa taggattact tgttttaact tggacaagtt
    25321 ggtttaagaa tctttttccg atttttgaaa ataaccaagt agcacgttta tttgtttttg
    25381 tagttcttct attaggttta gttctgagtt tgttagacat tagaagaatt aaaaaattta
    25441 taaacgaaca gataaggctt atcaacaatt tgtccaattg gaaaagaact cacttagttt
    25501 ataatcctga tctagtataa tttgtatttg aaactagtct ttagaaagta aaaattatta
    25561 tgttttatta aggaggtcta tttatggatc aacaaaacgg gttgtttggt tttcttgaaa
    25621 accatgttat gggaccaatg ggcaaacttg ctcagtttaa agtagtgcgt gctatcacgg
    25681 ctgcaggtat ggctgctgta ccatttacta ttgtaggatc aatgtttttg gtattcagta
    25741 ttttgccaca agctttctca ttttggccaa ttgtggcaga tattttctct gcttcatttg
    25801 ataaattcac atcactttac atggttgcaa actatgcgac tatgggttct ctatctcttt
    25861 atttcgttct atcacttgca tatgaattga caaaaattta tgcagaggaa gaagaactca
    25921 atatgaatcc tcttaatggt gccttgcttg ccttgatggc ttttgtcatg acagtaccgc
    25981 aaatcatttt tgatggtgga atgatgaaga ctgtgacaag tctaaaagaa ggtgcagtaa
    26041 ttgcagatgg atgggcaatg ggaaatggag tcgcacgttt tgggacaaca gggattttta
    26101 ccgcaatcat tatggcaatt gtgactgttc ttatttatcg tatgtgtgtt aaacataatt
    26161 gggttattaa aatgcctgaa gctgttccag aaggagtttc tcgtggattt accgctttgg
    26221 ttccgggatt tgtttttgca tttgttgtta tctttatcaa cggtcttctt gtagcaatgg
    26281 gaacagatat ttttaaagtc attgcaattc catttggttt tgtatccaat ctgactaatt
    26341 cgtggattgg tttaatgatt atttatctat tgactcaact actttggatt gtaggtatcc
    26401 acggtgcgaa cattgttttt gcatttgtta gtccaattgc tcttgctaac atggctgaaa
    26461 atgctgctgg cgggcacttc gctgttgcag gtgaattttc taatatgttt gtaattgcag
    26521 gtggttctgg tgcaacttta ggactatgtt tatatattgc ttttgcctct aaatctgaac
    26581 agcttaaagc aataggacga gcatctgtag ttccggcctt atttaatatt aatgaaccat
    26641 taatttttgg attacctatt atctataatc cagccttggc tataccattt attttagcac
    26701 caatggttac tgctactatt tattacgtag cgaattctct aaactttatt aagccaatta
    26761 tcgcacaggt tccatggcca actccagtag ggattggagc tttcttaggg acagcagatc
    26821 ttcgagctgt attagttgct ctagtatgtg catttgcagc attcctagtc tatcttccat
    26881 tcatccgtgt atatgatcaa aaattggtga aagaagagca aggtatctaa taagtaaaaa
    26941 agtatactcg atgatagaat ccatatagtt taaataatga gtgttaatat tagcagtgaa
    27001 gaggtctttt taagatattc ttctcttctt tttcatattt tttcgctatg tagggtatga
    27061 agcaaaatag aaagtagttc gaatagttga taaacaggaa actgctgtta tttaaaaaaa
    27121 acaataaagt aaagtatgtt atcgtagaat acgatacaat agtaaaaaag caaaaagaat
    27181 gcgttttata tttgggtttg aggtttataa aataggataa gcgtgctgaa aacttagata
    27241 tgacaaacaa aataaaattt ttaaaagcta catagaaaca tggtataatg tatctaaagg
    27301 aggtagcata tgtccttaga tatagataaa gaaaagatga caatcatggg aatagctttt
    27361 gaaaacagat ccgtttttaa gagtgtttgg tatgctttaa gtacaaatat gattgaagga
    27421 tggcgaccta cggttagtga tgttgaaaaa ttacgagatg aagctcttgc tctggggatg
    27481 acttaatgaa gcgcaactgt tatgagtctt atgactatgt tgatccggat aatttatata
    27541 ccgatccggg ttcttcagtt ctaagaaata agcaggaagg aaaaaagcac gcgagcttga
    27601 atatcgtatg attgctagta agagtttgaa attatttatc aatcctatct tagttaatag
    27661 tttaaaagta gtttgtttca caactgcata agcttagaaa agttgaaaag tgataactct
    27721 ttaataaact cttggtttgt taaaagatat tttgtccact acattttttc aattgactat
    27781 tatttgtcat agatataaca gatagaacat tgcattcaga ataatgaaaa acgcatcaaa
    27841 aatggtgcgt tctgttttta tgctaccata aaaggaggaa aacaaattga aaatttttaa
    27901 gggagagttt tatcgaatct ctgtattaac agacaagcta gtaaggttag aatactctca
    27961 aactggaagt tttgaggata gaacgacaca acttatctat aatagagatt ttggccaagt
    28021 ttcgttagat tatatcgaga catcaaacgt actagatatt atgacggact attttcatct
    28081 gcactttaat aaaggagaat ttaacgccga aaatttattt atagaattaa aaggaaattt
    28141 tgccgtatat ggtagtcgct ggtattttgg tgaatctatt gaaacgttaa aaggaacagc
    28201 tcggactctg gataaggcag atggagcaat ctcgttagaa gatggaatta ttagccgaaa
    28261 tggtatagcc ttattggatg attctcaagg atttatttgg gatgaacaat ctggttatat
    28321 tgagagagaa aatcaaattg acctgtattt ctttgcctat gggcatgatt atagaggagc
    28381 aatcagagac ttttaccatt tgactggttc aacacccttg ttgccaagat atgctttagg
    28441 caattggtgg agtagatatt ggccttatac gtcggatgaa tatttggatt taatagacag
    28501 atttgaaaca gagaaaattc cattatctat cggtgtgtta gatatggatt ggcatataac
    28561 tgacattcca gctcgttttg gaagtggctg gacaggatat agttggaata gaaacttaat
    28621 accaaatcca gaacagttat tgcaacaact tcatgataga aagttaaaac tctccttaaa
    28681 tgtccatcct gctgatggga tacgggctta tgaagaagct tatcctcaaa tcgcaaaacg
    28741 gttggggtta aatgtagaac tagaagaacc tgctattttt gattttttta atccctcttt
    28801 tagggaagcc tactttaaag atgttcatta tgagctagaa aagcagggag tagatttttg
    28861 gtggattgac tggcaacaag ggacacaagg tatgctagat ccactttggc ttttaaacca
    28921 ttatcactat caggatagtt gtaaaaatgc agaaggtggt ttgattttat caagatatgc
    28981 aggtcctggt agtcaccgct accctgttgg tttttcaggg gatactatta ttagttggaa
    29041 ttccttaaga tttcaaccct attttacagc gacagcatct aatatcggtt atagttggtg
    29101 gagtcatgat atcggtggac atatgttggg ggattatgac gaagagctac aaactagatg
    29161 gctacagttt ggtgttttta gtccgattac tcgattacat agttctagaa gtccttttaa
    29221 tagtaaagaa ccttggtttt tttcagaaac aacatctaag attatgaaga aataccttcg
    29281 tttgagacat cagatgattc cttatctata taccatgaat gtaaagacac atgaggaagg
    29341 tgccccatta atcagtccaa tctattattt ctatccagag aatgatgaga gctataatgt
    29401 tccaaaccaa tacttttttg gaacagaact gatggtggct cccattgtag aaaagatgga
    29461 tttgacattc caatctgcaa aagtagatgt atggttccct gaaggtgaat ggtatgactt
    29521 cttttcagag aaaaaataca caggtggtgt gaagttaagt gtttataggg acatctcgac
    29581 tacgcctgtg tttgcaaaaa gtggtgcaat cattcccttg gttggttctg agataggtat
    29641 gggtgttgat ttacctgagg ttgtagattg gtatgtattc ccagggaaac aacattcttt
    29701 tgaaatgctt gaagatcaaa atggtcaaag atataaaaca agattatcaa tcgattggga
    29761 aatgggaatg gtagagttag cattacaagg agattctagt atcgttccaa gcaatagaaa
    29821 acatagaatt cattttaaag gaacgaatgt gtctataatt gaattgccaa ataagaatga
    29881 tacagctaaa tttgaatgga aagataataa aaggacatct ttaaatgacg aagtttttag
    29941 actactaaag acagcttctc ttccatatga attaaaagat agattgttaa atcaattcat
    30001 caatgccaaa aactctcatg acttaatgaa tatcttgcat catcaggata aggaattgag
    30061 agggcgtttg ttggaaatga tatttactag ccaaaactaa ttgaaacaat tagaaagtca
    30121 tttgtttagt gtatatgaag attctgtatg gtattcgtta tcactggtca cattgaaaat
    30181 gtgaaataag cacctacaac atagacttta caacacttca tgtttcatat catggggtgt
    30241 ttttctattt aagtcaaagc caatcaaaaa atctcactat tcatcaggtt aaaggaaacc
    30301 taatcatagt gagattgtga attatagtag agtttgtatc gcctcttcaa tttgttttgg
    30361 gtctgttttt gaagaaaagc gttcaaagac ttgcccatct cgaccgatga gaaacttagc
    30421 gaaattccat tcgattcgtt ttcctagtgg gccagatttc tggtcttgta accagacata
    30481 gagagggtct gcttccttac cgttgacctt aatcttggca aaacgtggga aggtggtttg
    30541 aaaatgtagg ctacagaagg cgttgatttc ctctgcgctg ccgggtgctt gtcccataaa
    30601 ctgattgcaa gggaaatcca atatttcaaa gccctgatct tgatagcgtt catagagttc
    30661 ttgaagtccc tggtactggg gcgttaaacc acatccagta gcagtgttga caatcaagag
    30721 aactttgcca cgatagctat ccaagggagt tgcttggttg ttttggttca aaacggaaaa
    30781 atcataaagt gaagtcatga gggcctcttt tctttttcta cattgtaaca gtttttactt
    30841 ttttcgtcga gtcggatgga agatattgtt gaagaataag ccctcaatat gatagaaacc
    30901 gtttacaaat aactttaaaa atggtataat ttaattaaac cggtttactt agttgctata
    30961 aatctctaat ttgagattta gttcctattg attttacaat atgtttattg gagtgtatac
    31021 atgcaaacaa aaacaaagaa gctcattgtg agtttgtctt cacttgtttt atcaggattt
    31081 ttattaaacc attatatgac agttggagcg gaagaaacga ctacgaatac cattcagcaa
    31141 agccagaagg aagttcagta tcagcaaagg gatacaaaaa atttagttga aaatggtgat
    31201 tttggtcaga cggaggacgg aagcagtccg tggacaggaa gcaaagctca ggggtggtca
    31261 gcttgggtag accagaagaa tagttctgca gatgcctcaa ctcgagtcat tgaggctaag
    31321 gatggggcta tcactatctc aagccctgag aaattaaggg cagcggttca ccgtatggtt
    31381 cctattgaag ctaagaaaaa gtataaactg cgtttcaaga ttaaaacaga tcataaagtc
    31441 gggattgcca aagttcgtat cattgaggaa agtggtaagg acaagcgatt gtggaattct
    31501 gcaacgacgt caggaacaaa ggactggcag accattgaag cagactatag cccgacttta
    31561 gatgttgata aaatcaagct ggagttattc tatgaaacag gaactgggac tgtttccttt
    31621 aaggatattg agctggtaga ggtagcagac cagctttctg aggattctca aacagataaa
    31681 cagcttgagg aaaagattga tttaccaatt ggaaaaaaac atgttttttc tcttgcggac
    31741 tatacttata aggtagaaaa tcctgacgtt gcttcagtca aaaatggaat tttagaacct
    31801 cttaaggaag ggacaaccaa tgtcattgtc agtaaagatg gcaaggaagt gaaaaagatt
    31861 cctttgaaga ttctagcctc tgttaaggat gcatacacag accgtttgga tgactggaat
    31921 ggcatcattg ctgggaatca atactatgat tctaaaaatg aacagatggc caaattaaac
    31981 caggaattgg aaggaaaggt agctgatagc ctatctagta tttcaagtca ggcggaccgc
    32041 acctatttgt gggaaaaatt ttcaaattat aaaatgtctg caaatctgac tgccacttat
    32101 cggaaattgg aggagatggc caagcaagtg accaatcctt cttctcgtta ttatcaagat
    32161 gaaactgtcg ttcgaacagt cagggattcc atggaatgga tgcataaaca tgtctacaat
    32221 agtgaaaaga gcattgttgg gaactggtgg gattatgaaa tcggtacacc tcgtgccatc
    32281 aacaatacct tgtctctgat gaaagaatac ttctctgatg aggaaattaa aaaatataca
    32341 gatgtgattg aaaaatttgt accagatccc gaacatttcc gaaagacgac tgataaccca
    32401 ttcaaggctc taggtggaaa cttagttgat atgggaaggg taaaagtaat agctggttta
    32461 ctgcgtaagg atgatcaaga aatttcttct accattcgct cgattgagca agtgttcaag
    32521 ttggtagacc aaggtgaagg tttttatcaa gatggatcct atatcgacca taccaatgtt
    32581 gcctatacgg gtgcttatgg gaatgttttg attgatggcc tgtctcaact gttgccagtc
    32641 attcaaaaga ccaagaatcc aatcgataaa gataaaatgc aaaccatgta ccactggatt
    32701 gataaatcgt ttgctccttt gctggtgaat ggagagctga tggatatgag tcgtggacgc
    32761 tcgatcagtc gtgcaaatag cgaggggcac gtggccgcag tagaagtact aagagggatt
    32821 caccgaatag cggatatgtc tgaaggagaa accaaacaac gtttgcagag tcttgtgaag
    32881 accattgttc aatcggatag ttattatgat gtctttaaga atttgaagac ttataaggat
    32941 atcagtttga tgcaatcctt gttaagtgat gcaggagtcg caagtgttcc aagaacaagt
    33001 tacctatctg cctttaacaa gatggataaa acagccatgt acaatgcaga gaaagggttt
    33061 ggatttggct tgtcactctt ttccagtcgt accttgaatt acgaacacat gaacaaggaa
    33121 aataaacatg gttggtatac gagtgatggg atgttctatc tttacaatgg cgatttgagt
    33181 cactatagcg atggctactg gccaacagtt aatccatata agatgcctgg tacaacagag
    33241 acggatgcta agagagcgga tagcgataca ggtaaagttc taccgtctgc tttcgttgga
    33301 acgagcaaac tagatgatgc caatgcgaca gcaaccatgg atttcaccaa ctggaatcaa
    33361 acattgactg ctcataagag ctggtttatg ctgaaggata agatcgcctt tttaggaagc
    33421 aatatccaaa acacttcaac agatactgct gcaactacaa ttgaccagag aaaactggaa
    33481 tcaagtaatc catataaagt ctatgtcaat gataaagaag cctcccttac agaacaagaa
    33541 aaggattatc ctgaaaccca aagtgtcttt ttagaatcgt ccgattcgaa aaagaatatt
    33601 ggttactttt tctttaagaa gagttcaatc agtatgagta aggctttgca aaagggagcc
    33661 tggaaggata tcaatgaagg acagtcagac aaggaagttg aaaatgaatt tcttacgatt
    33721 agtcaggctc ataagcaaaa tggagattct tatggctata tgctcattcc taacgtggat
    33781 cgtgccacct tcaatcaaat gataaaagag ttagaaagta gcctcatcga aaataacgaa
    33841 acccttcagt ctgtttatga tgctaaacaa ggagtttggg gcattgtgaa atatgatgat
    33901 tctgtctcta ctatttccaa ccaattccaa gttttgaaac gtggagtcta taccattcga
    33961 aaagaagggg atgaatataa gattgcctac tataatcctg aaacccagga atcagctcca
    34021 gatcaggaag tctttaaaaa gctagaacaa gcagctcagc cacaagtaca gaattcaaaa
    34081 gaaaaggaaa aatctgaaga ggaaaagaac cattcggatc aaaagaatct ccctcagaca
    34141 ggagaaggtc agtcaatctt ggcaagtcta gggttcttgc tacttggggc gttttattta
    34201 ttccgtagag gaaagaacaa ctaatttgtt catcatctag atgaattaca tgaaactgtg
    34261 gaaaatagaa aaaatccgaa gaaggccaaa tatcttcgga tttttctttt aaaaaaggat
    34321 aagttgatac ttatcctttt ttacttcatt atgtgactat agcgttttga aactagaata
    34381 ggacgttata actactaaaa gatttctata aattcatttg attttcctaa tcaatttgtt
    34441 cgtatcctat ttcactccac tatattagtc cgtctcgctc cgtgaggtgc gagacaaaac
    34501 aaccacccgc tatacgggtg cgcgtcgaag gttataccaa aaaaactcca aacgcgatac
    34561 aataaaggtg ttcaatccac ttgtaaagcg aaaggagaaa aaatatggca caaaaggctc
    34621 atagtttatc tcacacaaag tggaggtgtt ctatcacatt gtgttcaccc ctaagtatag
    34681 acgaaaagtc atctataatc aatatagaag tagtttaggc gaaatatttc atcgcttgtg
    34741 tagttataaa ggtgttgaaa tgatcgaggg tcacttaatg ccagaccatg tacacatgtt
    34801 agtcagtatt ccgtcgaggc taagtgtttc aagttttatg gggtatttaa aaggcaaaag
    34861 tgcactcatg atgtttgaca aacacgccaa tctcaagtac aagtttggga atcggcattt
    34921 ctgggcggaa ggttattatg taagtccagt agggcttaat gaagccacaa ttaagaaata
    34981 tagtcaagat taaagaaatt atcgagtgga tgatttcttc acgagtatga aaatttgaga
    35041 actagtaaag tatgatatat agtaaaatga aataagaaca ggacaaaatc gatcaggaca
    35101 gtcaaatcga tttttaacaa tgttttagaa gtagaggtat actattccag tttcaatcta
    35161 ctatagcact agataaattg agtgtaaaag aatataagga tccctttagg gatagtggta
    35221 agtaatacca aagtctctta aagaggcaag tgacgagtca agagcaataa ggcttgaaca
    35281 acgtgaaagc cagcgtcttt aggcgctggc tgatgatttg ggcttatagc tctgagataa
    35341 accacccgtt agacgggtag ttatgatttt atctgagtgt aatatactgt tgggcaatct
    35401 cgctgatgcg gtcaaagttg ccttgggaag cgagtttatt gagttcgcca ccaattccaa
    35461 cggcatctgc accagcagcg aaccattgag ggatgttgtt taggccgact cctccggtta
    35521 ccattacgga aacttgtggg atcggtgcct tgactgcaga gatatatgct ggactgagag
    35581 tactacctgg gaagagtttg atgatttcac taccggcttc aagtgcagtc gtgatctctg
    35641 tgagggtaat acagcctgga atgtacggtg tgctgtagag attgcacatt ttcgcagttt
    35701 cagcatggaa agatggagaa acaacgtaat ttgctccagc tagaatggca tctctagcag
    35761 ttacggcatc aagcacagta cctgcaccga tacaaacact ctgatcgtcc tgatacaagt
    35821 ctacaagttc cttgatgatt tgtcctgcat actgattggt ataggcgatt tcaatagctt
    35881 tgataccgcc cttgatacaa gcaatcgagg cttgtagtcc ttcttccttt gtatttcctc
    35941 gaatgacagc gacaattttc tgttttttta gttcaataat cgtatctgat ttggtcatgt
    36001 aattctccta acgaatgata tcttgtgcat ttgccagtaa attttcaata ctagttgcgg
    36061 aagtggagag atggtctcct ggaagagtgc atttgagagt tgcgctcgca actgcaaagt
    36121 caatggtagt ttttagggag gaatgatgga gtagttggta aagggcacca gatataaagg
    36181 catccccgct accaattcgt tgatagactg cagtttttag ttggacagac tcttcaaatc
    36241 gttcttccag agcataggct tgatagacat ttttgtcttg ctcatcacta gatcggaggg
    36301 tatggaaaat ggccttgaaa ccataggctt cttttaaaag tcgcatgcga ttttccacct
    36361 cttctaggct agcactgtct cttggaaaca tctctagatt ttggtcatca atcatgagag
    36421 gatcaatacc gaagcaatag tcagtaaaac gtgcaaactt agaaaattca tacttggctt
    36481 ctaggactga aatcatcttt gttctcagat tgagatctat tgaaacgaca attcctcggc
    36541 gcttggcttc ttccaagagt aggagaagga tcgcacggac ctcttgaccg atagctatgg
    36601 tgattccact aaaatgaaaa tggctaatcc cctgaaagag agaatccata tctagcatgt
    36661 ttggccgaat ctggctgata ctcgtatgct tacgatcgta gaaaacttca ctttgacgac
    36721 aaccaaagcc gttctccaaa tagtagaggc cgattcgatc gccaagccga cagattgaac
    36781 tggtatcgat ttggtgctgt ttcaagaatg tgagaaaacg atctccaatc tcgttggcag
    36841 ggagtgcggt aaagactttc gttgagatac ccagggcttg caaattacaa gcgatgttaa
    36901 tttctgatcc gccaaaataa gtcgaactgg caacatgatc gccgatactg gtggcatcta
    36961 atggtgagat tcgaattaat ggttcgccaa acagtaatat tttcgtcatc cattagttcc
    37021 tttctggttt agaatagctt tacttggcta atacttcttt caaataagca gcgacttcat
    37081 catcttgaca gttttcaaag aagtattctt ggaagtattt gccagagatg gtgtctttga
    37141 ggaagtcttg gtcgattgtt ttaaggatgg tcatcaaatc attgtgggtg atttgtttca
    37201 cctcgtttaa gatacgagcg ttgcgttgtt cagggattac acgttctctt gggtagccac
    37261 cgcccatttc ttcagcaaat aagcgttcaa acatcaattt gagggtcagt tctgcccccc
    37321 agccaaatcc tttggcataa gggatagaca aggcgttacc accattgatt tgagaataaa
    37381 ggtaagcgtc agttgggtcc actgctagac cacagataac accagggaag ctgtttaagg
    37441 caagcatagc ccctacaccc gtaccacagc cggtaacaac aaagtcaact gcctttgtat
    37501 ttaaaaggat ggcagccatt agtccgttct gcacataagt taattgactt tctccttctt
    37561 ctccacgcat accatagtta aataattggt agtctttttt atctgtcgct tcttttagac
    37621 tatcgtaaat aatgtgattc ttgctagctt gactattttc attgattaat gcgattttca
    37681 taagatcttc tttctatttt tactcaggtt gttttccgat gtaggctaag ataccgccat
    37741 ctacatatag gatgtggcca ttgacaaaat tgctggcatc actagcgaga aagacagcag
    37801 ggcccatcaa atcttcagga tttccccaac gtgcagcagg tgtttttgca atgatgaact
    37861 ggtcaaatgg gtggcgagaa ccatcttctt gcaactcacg aagaggtgct gtttgaggag
    37921 tggcaatata acccggtcca attccgttac attggatatt ggctccaccg tattcagacg
    37981 caatgttgcg ggtcaacatt ttcaagcccc ctttagcagc agcataagcg ctaactgttt
    38041 cacgtcccag ttcgctcatc atcgaacaaa tattgataat ctttccatgc cctttcttta
    38101 tcatagaagg aataactgcc tttgaaacga taaatggtgc gtttaagtca atatcgatga
    38161 ccttacggaa atcagcggcg ctcatttcgc acattggaac tcggcggata ataccagcgt
    38221 tattaacgag gatgtcaatg acaccaacct cttgttcgat ttgcttgacc atggcttgga
    38281 taccgtcctc gtctgtcacg tcacagacat atccatgggc ttggatgcca acttcacgat
    38341 aagcttcaat ccctttattg accagatctt gattgatatc gttaaagaca atagtagcgc
    38401 cggcttcagc gtaggatttg gcaatagcaa atccaattcc ataagaagcg ccggtgatga
    38461 gagcaatttt tccttttaaa gaaaactgct caattgagaa tgatgtattt gtcatttgat
    38521 acttcctttc aaatttgtta agacttctct ataaccaaat tatattctag taaaccggtt
    38581 ttgtcaataa ataaatattt ttatttataa aaagatttgt ttttctaaaa aaacggaaga
    38641 ttttgaaatt tctgtctatt aaaatggtta aaaagataat gaaagcgcta atattttttt
    38701 aaaaaaacta ttgacaagat aaaaataaag gattacaatg ggggatataa agtaaaccgg
    38761 taaacctaaa caagaaagga gaaaagatga aaattgtact tgtagggcat ggacattttg
    38821 ctacagggat ttatagttct ttacaattga ttgcaggcaa tcaagaaaat gtggaggcga
    38881 ttgactttgt ggaaggaatg tcagcagatg aactcaagca aaaaatctta cttgcaattt
    38941 caaatgaaga agaagtttta atcctaagtg atctcttggg aggatcgcca ttcaaggttt
    39001 cttctaccat aatgggagaa aatccagcca agacaatgaa tgttctctcg ggtttgaact
    39061 tagccatgtt aatggaagca gtctttgcta gaatggctca tagctttgat gaggttgtta
    39121 ataaatcagt agtggcggcc cagggcggag ttgtaaatgg taaagaattg ttttcaacgg
    39181 atgcagagga agaggaagaa gatttcgaat tgggtattta aagggtaaaa gaatgataaa
    39241 aaaggttacg attgaaaaaa taaaatcgcc tgagcgcttc ttagaagtac cacttctgac
    39301 gaaagaagaa gtcggccagg caatcgataa ggttattcgg cagttagaac tcaaccttga
    39361 ctatttcaag gaagatttcc cgacgccagc tacctttgat aatgtctatc caatcatgga
    39421 taacacggaa tggaccaatg gtttctggac aggagaactg tggttggctt atgaatacag
    39481 tcaacaggat gcatttaaaa acatcgctca taaaaatgtt ctttctttcc tggatcgtgt
    39541 caataagaga gtagaattgg atcaccatga tctcggcttc ttgtacacac cgtcttgtat
    39601 ggctgaatat aagataaatg gagatggaga ggctagagaa gcaaccttga aagctgcaga
    39661 taagttgatt gaacgctatc aagaaaaagg tggttttatt caagcttggg gagacttggg
    39721 caagaaagag cattaccgtt tgattatcga ctgcttgctc aatatccaac tcttattctt
    39781 tgcttatcaa gaaacaggcg atcaaaaata ctatgatatt gcagaaagtc atttctatgc
    39841 ttcagctaat aatgtaatcc gtgatgacgc ttcgtccttc cacaccttct attttgatcc
    39901 tgagacaggt caacccttta aaggtgtaac gagacaaggg tatagtgatg attcatgctg
    39961 ggcacgtggt cagtcatggg gagtttatgg tattcctttg acttatcgtc acttaaaaga
    40021 cgagtcctgc tttgacttgt ttaagggtgt gaccaattat ttcttgaatc gtctgccaaa
    40081 agatcatgtg tcctattggg atttgatttt taatgatggt agtgatcaat cacgagattc
    40141 ttcagcaaca gctatcgccg tctgtgggat tcatgaaatg ctaaaacatc ttccagaggt
    40201 ggatgctgac aaagatattt ataaacatgc tatgcatgcc atgcttcgtt ccttgatcga
    40261 acattatgca aatgatcaat ttacccctgg tgggacaagt ctcctccacg gtgtgtactc
    40321 atggcattca ggtaaaggag tggatgaagg caatatctgg ggtgactact attacctaga
    40381 agcccttatc cgtttctaca aagactggaa cctatattgg taggaggaga aatatgacaa
    40441 tgccaaatat tattatgacc cgtatcgatg aacggttgat tcatggacaa ggacaacttt
    40501 gggtaaaata cctaggttgt aatacggtca ttgttgccaa tgacgaagta agcacggaca
    40561 agatgcaaca aactctgatg aaaacagttg tgccagactc agttgccatg cgtttcttcc
    40621 ctttgcaaaa ggtgattgat atcattcaca aggctaatcc tgctcaaacg atctttatcg
    40681 ttgtaaagga tgtaaaggac gctttaacct tggtagaagg tggtgtccct atcaaagaaa
    40741 tcaatattgg gaacattcac aatgcccctg gtaaagagca agtgacacgc tccatcttcc
    40801 tgggtgaaga ggacaaggca gccctcaagg aattaagcca aactcatcaa gtaacattta
    40861 atacgaaaac aactccaaca ggaaatgatg gagctgttca agtcaacatt atggactata
    40921 tttaaaagag gagatcgtta tgtcgattaa tgtatttcaa gcgattttaa ttggattatg
    40981 gacagctttc tgttttagtg gaatgctgtt aggaatttac accaatagat gtattgttct
    41041 gtcatttggt gtcggaatta ttctaggtga tctgcctact gctcttgcaa tgggagctat
    41101 tggtgaattg gcttatatgg gattcggtgt tggtgctgga ggtactgttc caccaaaccc
    41161 aatcggacct ggtatctttg gtaccttgat ggctatcact agtgctggta aagtcagtcc
    41221 agaagcggct cttgccctct ctactccgat tgctgtggcg attcaattct tacaaacttt
    41281 cgcctacact gtacgtgctg gtgcgcctga aacggcgatg aagcacttga aaaaccataa
    41341 tttgaagaaa ttcaagttca ctctaaatgc aacaatttgg ttgtttgcct ttattggatt
    41401 taccttgggt tgcttgggtg ccctttcaat ggataccttg ttgaaactcg tagactacat
    41461 tccaccggta ttacttacag gtttgacagt tgctggtaaa atgctcccag ctatcggttt
    41521 tgcgatgatc ttgtcagtga tggctaagaa agagttgatt ccctttgtct tgttgggata
    41581 tgtttgtgca gcttatctaa acatcccaac aattggtatt gcaattgtag gtactatctt
    41641 tgctttgatt gaattttata acaagccaaa aacagcggat catgtggtag aggaggaagc
    41701 acacgatgac tggatctaac aaattaacaa aacgtgatta tcttaaaacg tctttgcggg
    41761 cattcttttg tcaaaatgga tttaactata gtaactatca agggttggga tatgccaatg
    41821 tgatgtatcc tgctttgaaa aaacactatg gagaggatca ggaaggtttc taccaagcct
    41881 tggaagaaaa ctgtgaattc tataatacca acccacactt cctgcctttt attaccagct
    41941 tgcatcttgt aatgttggaa aatggtcgac caacaaaaga aacacgtagc atcaagatgg
    42001 ccttgatggg accattggca ggtattgggg attctctttc tcaattctgt ttagctccat
    42061 tgttctcaac catcgcagct tcgtttgctc aagaaggctt ggttgtcggt ccaatcttgt
    42121 tcttccttgc gatgaatacg attttaacag cgattaaatt gtcaactggt ctgtatggat
    42181 acaaactagg aacaactgtg attgataaac taagcgagca gatggcaacg atttctcgta
    42241 ttgccaatat tatcggtgta accgtaattg ctggtttggc agcgacatct gttaagatta
    42301 tggtgccgat tacctttgct gcaggggaag ttaaagcaga cgctaaacaa agtatcgtaa
    42361 gtattcaggg aatgcttgat aaggttgctc cagctcttct accagcccta tttacacttt
    42421 tagtttacta cttgatcaaa gaaaagaaat ggacaacata taaactcgtt attttaacag
    42481 ttatcatcgg aattatcgga agctggctta agattatagc ttaatggata caacattgtt
    42541 ttatggaata gtgattgtct tggcagtgag tcccctttta ctgtcaagct ttcattatat
    42601 tcgtcagcaa aagttgcttc gcaaacagat ggagcaacga caagagtatt tagcttcttt
    42661 aacatctggt gatgaagtgt tgttattgtc tggaattcat ggaaaaatca tttctatcca
    42721 agatgacttg gtctccttgc agattgcaaa aggtgtggtc atctatgtag aaaaggaaag
    42781 tgtaatggga aagacaaaag aactgctttt taagtagttc tttttctggt aatagataat
    42841 gaaagaagaa agaagacaat tttttgaaag aatcgatgga aaccaatgtc gtgattatat
    42901 cttgtcccac tgttcaaaag actatgagaa agtcaagagt tcccttgaac gcttgatgga
    42961 caatcgtttt atgtttgata gtccttggga tatggagcct tgttcaaaaa tccatcaaat
    43021 ccagccgatg gtatgggatc aagtatttga agatgatcca gaatgggctt atatgctcaa
    43081 tcgacaagaa tatctcttgc agtttatgat agggtatgtg gtagaaggag ataagagcta
    43141 tattcaaaag tgcaagttct ttctatttga ttggattgag caggtgagag aattttctcc
    43201 tcaatccttg atgactagaa ccttggatac gggtattcgt tcctttactt ggttgaaact
    43261 actcttgctt ctcttgaaat ttgacttgct agaggagaaa gaactagaga aaattttggt
    43321 cagtctagaa aagcagattg actttatgaa aagctactat cgcgccaagt acacccttag
    43381 taactggggg attttacaaa caattccgat gcttgctatc tatcatttct tttcagataa
    43441 gatggatcta gaagaagctt accattttgc ttcagaggag ttgaaacagc aaattgagac
    43501 acagatttta ggagatggaa gccagtttga acagtcgatt ctctatcatg tagaggttta
    43561 taaagccttg ctggatttgt gtctcttgct tccagacttg caagatagtt accaagagtt
    43621 gctggaaaag atggcgacct atattcaaat gatgacaggc ttagatggac ggactttggc
    43681 ttttggtgat agcgattcta cagaaacgac agaaatgttg agcctgtctg ctgtggtttt
    43741 gaaccaggaa gaccttctta acggtctgga tgttaaagtt gatttgctta gcctcttgtt
    43801 cctggggcga gaaaaggtca agcgactgca ggaatttgaa aagagagctt ggcagcctaa
    43861 gtccatgatc tttgaagact ctggacatgt ctgcattaag gatgaacatc gttatctatt
    43921 tttcaaaaat ggtccgctag gaagtgccca tagtcatagt gacgagaata gtttttgctt
    43981 acagtatcaa ggccaaccta ttttcataga tgctgggcgt tattcttatc gggagatata
    44041 tgaacgttat ctcttaaaga gtgcttggag tcattcgacc tgcattgtag atgggaaagc
    44101 tccggaaaga atcacgggat cctgggaata tgaatactat cctcactccc tgttttgtca
    44161 ccataaagaa agggagggag tgcattatat tgagggggct tattggtcag cagaacctga
    44221 tttgccttat cttcacagga gaaaaatcct catgttggta gaggatgtct ggctcttggt
    44281 agatgacatc aggtgtcaag gtcaacatga ggtgttgact cagtttatcc ttgacaagga
    44341 tgtgacctat caagatggga aaatcaatca gttgagacta tggagtgaag ttgattttga
    44401 tttggaagat accatcattt ctcctaaata caatgagctt gaaagaagta gcaaactcac
    44461 caagcgccaa ttctttgaga atcagatgct ggattatacc atcattgcgc atgagagttt
    44521 tgaaatcatc cgtcattctg tctaccagac agatgatcgt gaagtggaaa atgctctggc
    44581 ttttgaagtg aaaaatgatg aaacagacaa gctgattctg ttattaagcg aggatattgg
    44641 tgtaggtgaa aaattgtgcc tcgttgacgg aacaaaaatg cgtggaaaat gtttagtata
    44701 tgataaaata aatgagagaa tgattcgctt gcagtgctag aaataggcat tttgaatagt
    44761 gaatatgtta taataagtat tagtaggagg tgttttagat tggagaagaa actgaccata
    44821 aaagacattg cggaaatggc tcagacctcg aaaacaaccg tgtcatttta cctaaacggg
    44881 aaatatgaaa aaatgtccca agagacacgt gaaaagattg aaaaagttat tcatgaaaca
    44941 aattacaaac cgagcattgt tgcgcgtagc ttaaactcca aacgaacaaa attaatcggt
    45001 gttttgattg gtgatattac caacagtttc tcaaaccaaa ttgttaaggg aattgaggat
    45061 atcgccagcc agaatggcta ccaggtaatg ataggaaata gtaattacag ccaagagagt
    45121 gaggaccggt atattgaaag catgcttctc ttgggagtag acggctttat tattcagccg
    45181 acctctaatt tccgaaaata ttctcgtatc atcgatgaga aaaagaagaa aatggtcttt
    45241 tttgatagtc agctctatga acaccggact agctgggtta aaaccaataa ctatgatgcc
    45301 gtttatgaca tgacccagtc ctgtatcgaa aaaggttatg aacattttct cttgattaca
    45361 gcggatacga gtcgtttgag tactcggatt gagcgggcaa gtggttttgt ggatgcttta
    45421 acagatgcta atatgcgtca cgccagtcta accattgaag ataagcatac gaatttggaa
    45481 caaattaagg aatttttaca aaaagaaatc gatcccgatg aaaaaactct ggtatttatc
    45541 cctaactgtt gggccctacc tctagtcttt accgttatca aagagttgaa ttataacttg
    45601 ccacaagttg ggttgattgg ttttgacaat acggagtgga cttgcttttc ttctccaagt
    45661 gtttcgacgc tggttcagcc ctcctttgag gaaggacaac aggctacaaa gattttgatt
    45721 gatcagattg aaggccgcaa tcaagaagaa aggcaacaag tcttggattg tagtgtgaat
    45781 tggaaagagt cgactttcta aaatgaagga aaatgacttg caatttctgt taagaaataa
    45841 aataatccca cctagaacaa gctaggtggg attatttgcc tatgaaatga gaaattatgg
    45901 gagcaagctc ctaaatcaac tgtttttgat ctacttcttt aactacttga taaaagttat
    45961 agaagtaggt caaacttgaa atgatggtta cgactaggaa tattgaaaat ttccattgga
    46021 cagggttggt taaaagttgt ggaaaggata tgaggagaaa gaagagggct gcgttgagga
    46081 caggtatccg ttttgattgt attttctcaa gtcctttatt gagcgcagga agaaagagga
    46141 gtaggagtag taaaactgta tgagaaacag ctcctgaaat aagggcgaag aaaaggaaaa
    46201 tactgataaa aacatgaatg atcagtagtc tagctagtga tttcataagg cacctcctaa
    46261 tcctggtctt ttttagctct tgcaatacga agtgagtcga caatatgtat catcactccg
    46321 aaaaagaaag ctcccagtat agttttaaaa atatgttttg tatttagaag agaactgata
    46381 aaatttggat tttcacttgt tagggtatca atgagtggaa ttataaaaaa tatcactgtt
    46441 ccataaatcg aacctgcttt cagacctgga taacgtaact gtctcttttc ttttttcata
    46501 gggcacctcc taatcctcat cttgattttt cttagttttt gcaatgcgac gggagatgag
    46561 gaactgtatg ctcgctccga agaaaataga accgagaatg cttgatacac catttcttat
    46621 agtgagaaga gaatgaaaat agtcctgacc ttcacctatg agtatcctga gaagaggagt
    46681 tataaaaaac atccatagac caaagaacaa acctgctttc agacctgggt agtgtagttg
    46741 cttgctttct ttctcattca gcatatctgg ttcaatgact gtgatgcctg tttttttcat
    46801 ttggtaggtg acatagccag cagcgatgag ggcaatcact aaaatcagag gaggatagat
    46861 tagagccact tcttgagggt atttataggc cagaaggagt ggaataagat ttccgaaaat
    46921 catcagataa aagaggacga taaaaacttg gttccgaata ctatcggcct cacgccgttt
    46981 gtattcgtca aggggaccag aaataccgta tgtgcgtttg atcagttttt cagtgaaggt
    47041 ttcttttttc ataagtttgc tcctttttta aaaatcttcc tcccaaaaga gactgttgag
    47101 gtcagtttgg aggctgcggg cgagattgag acagagttcc aaggttggat tgtacttgtc
    47161 gttttcaatc atattgatag tctgtctcga gacaccgata tccttggcga gttcgagctg
    47221 ggaaataccc aattccttgc gaaattcttt cacacgattc atctgttctc ctttctgatt
    47281 tatgtcgtat atatttgact atattatagt cttttaaaca taaagtgtca agtatttttg
    47341 acatattttt tgaagaaata gtagtctcct tgtcctattt gtctgacaag tgcaagctgg
    47401 tcggatttgt ggtaaaatag ataagatatg acaaaagaat ttcatcatgt aacggtctta
    47461 ctccacgaaa cgattgatat gcttgacgta aagcctgacg gtatctacgt tgatgcgact
    47521 ttgggcggag caggccatag cgagtattta ttaagtaaat taagtgaaaa aggccatctc
    47581 tatgcctttg accaggatca gaatgccatt gacaatgcgc aaaaacgctt ggcaccttac
    47641 attgagaagg gaatggtgac ctttatcaag gataacttcc gtcatttaca ggcacgtttg
    47701 cgcgaagctg gtgttcagga aattgatgga atttgttatg acttgggagt gtctagtcct
    47761 caattggacc agcgtgagcg tggtttttct tataaaaagg atgcgccact ggacatgcgg
    47821 atgaatcagg atgctagtct gacagcctat gaagtggtta atcattatga ctatcatgac
    47881 ttggttcgta ttttcttcaa atacggtgag gataaattct ctaaacagat tgcgcgtaag
    47941 attgagcaag cgcgtgaagt gaagccgatt gagacaacga ctgagttagc agagattatc
    48001 aagttggtca aacctgccaa ggaactcaag aagaagggtc atcctgctaa gcagattttc
    48061 caggctattc gaattgaagt caatgatgaa ctgggggcgg cagatgagtc catccagcag
    48121 gctatggata tgttggctct ggatggtaga atttcagtga ttacctttca ttccttagaa
    48181 gaccgcttga ccaagcaatt gttcaaggaa gcttcaacag ttgaagttcc aaaaggcttg
    48241 cctttcatcc cagatgatct caagcccaag atggaattgg tgtcccgtaa gccaatcttg
    48301 ccaagtgcgg aagagttaga agccaataac cgctcgcact cagccaagtt gcgcgtggcc
    48361 agaaaaattc acaagtaaga gggaaaaaga tggcagaaaa aatggaaaaa acaggtcaaa
    48421 tactacagat gcaacttaaa cggttttcgc gtgtggaaaa agctttttac ttttccattg
    48481 ctgtaaccac tcttattgta gccattagta ttatttttat gcagaccaag ctcttgcaag
    48541 tgcagaatga tttgacaaaa atcaatgcgc agatagagga aaagaagacc gaattggacg
    48601 atgccaagca agaggtcaat gaactattac gtgcagaacg tttgaaagaa attgccaatt
    48661 cacacgattt gcaattaaac aatgaaaata ttagaatagc ggagtaagat atgaagtgga
    48721 caaaaagagt aatccgttat gcgaccaaaa atcggaaatc gccggctgaa aacagacgca
    48781 gagttggaaa aagtctgagt ttattatcta tctttgtttt tgccattttt ttagtcaatt
    48841 ttgcggtcat tattgggaca ggcactcgct ttggaacaga tttagcgaag gaagctaaga
    48901 aggttcatca aaccacccgt acagttcctg ccaaacgtgg gactatttat gaccgaaatg
    48961 gagtcccgat tgctgaggat gcaacctcct ataatgtcta tgcggtcatt gatgagaact
    49021 ataagtcagc aacgggtaag attctttacg tagaaaaaac acaatttaac aaggttgcag
    49081 aggtctttca taagtatctg gacatggaag aatcctatgt aagagagcaa ctctcgcaac
    49141 ctaatctcaa gcaagtttcc tttggagcaa agggaaatgg gattacctat gccaatatga
    49201 tgtctatcaa aaaagaattg gaagctgcag aggtcaaggg gattgatttt acaaccagtc
    49261 ccaatcgtag ttacccaaac ggacaatttg cttctagttt tatcggtcta gctcagctcc
    49321 atgaaaatga agatggaagc aagagcttgc tgggaacctc tggaatggag agttccttga
    49381 acagtattct tgcagggaca gacggcatta ttacctatga aaaggatcgt ctgggtaata
    49441 ttgtacccgg aacagaacaa gtttcccaac gaacgatgga cggtaaggat gtttatacaa
    49501 ccatttccag ccccctccag tcctttatgg aaacccagat ggatgctttt caagagaagg
    49561 taaaaggaaa gtacatgaca gcgactttgg tcagtgctaa aacaggggaa attctggcaa
    49621 caacgcaacg accgaccttt gatgcagata caaaagaagg cattacagag gactttgttt
    49681 ggcgtgatat cctttaccaa agtaactatg agccaggttc cactatgaaa gtgatgatgt
    49741 tggctgctgc tattgataat aatacctttc caggaggaga agtctttaat agtagtgagt
    49801 taaaaattgc agatgccacg attcgagatt gggacgttaa tgaaggattg actggtggca
    49861 gaatgatgac tttttctcaa ggttttgcac actcaagtaa cgttgggatg actctccttg
    49921 agcaaaagat gggagatgct acctggcttg attatcttaa tcgttttaaa tttggagttc
    49981 cgacccgttt cggtttgacg gatgagtatg ctggtcagct tcctgcggat aatattgtca
    50041 acattgcgca aagctcattt ggacaaggga tttcagtgac ccagacgcaa atgattcgtg
    50101 cctttacagc tattgctaat gacggtgtca tgctggagcc taaatttatt agtgccattt
    50161 atgatccaaa tgatcaaact gctcggaaat ctcaaaaaga aattgtggga aatcctgttt
    50221 ctaaagatgc agctagtcta actcggacta acatggtttt ggtagggacg gatccggttt
    50281 atggaaccat gtataaccac agcacaggca agccaactgt aactgttcct gggcaaaatg
    50341 tagccctcaa gtctggtacg gctcagattg ctgacgagaa aaatggtggt tatctagtcg
    50401 ggttaaccga ctatattttc tcggctgtat cgatgagtcc ggctgaaaat cctgatttta
    50461 tcttgtatgt gacggtccaa caacctgaac attattcagg tattcagttg ggagaatttg
    50521 ccaatcctat cttggagcgg gcttcagcta tgaaagactc tctcaatctt caaacaacag
    50581 ctaaggcttt agagcaagta agtcaacaaa gtccttatcc tatgcctagt gtcaaggata
    50641 tttcacctgg tgatttagca gaagaattgc gtcgcaatct tgtacaaccc atcgttgtgg
    50701 gaacaggaac gaagattaaa aacagttctg ctgaagaagg gaagaatctt gccccgaacc
    50761 agcaagtcct tatcttatct gataaagcag aggaggttcc agatatgtat ggttggacaa
    50821 aggagactgc tgagaccctt gctaagtggc tcaatataga acttgaattt caaggttcgg
    50881 gctctactgt gcagaagcaa gatgttcgtg ctaacacagc tatcaaggac attaaaaaaa
    50941 ttacattaac tttaggagac taatatgttt atttccatca gtgctggaat tgtgacattt
    51001 ttactaactt tagtagaaat tccggccttt atccaatttt atagaaaggc gcaaattaca
    51061 ggccagcaga tgcatgagga tgtcaaacag catcaggcaa aagctgggac tcctacaatg
    51121 ggaggtttgg ttttcttgat tacttctgtt ttggttgctt tctttttcgc cctatttagt
    51181 agccaattca gcaataatgt gggaatgatt ttgttcatct tggtcttgta tggcttggtc
    51241 ggatttttag atgactttct caaggtcttt cgtaaaatca atgaggggct taatcctaag
    51301 caaaaattag ctcttcagct tctaggtgga gttatcttct atcttttcta tgagcgcggt
    51361 ggcgatatcc tgtctgtctt tggttatcca gttcatttgg gatttttcta tattttcttc
    51421 gctcttttct ggctagtcgg tttttcaaac gcagtaaact tgacagacgg tgttgacggt
    51481 ttagctagta tttccgttgt gattagtttg tctgcctatg gagttattgc ctatgtgcaa
    51541 ggtcagatgg atattcttct agtgattctt gccatgattg gtggtttgct cggtttcttc
    51601 atctttaacc ataagcctgc caaggtcttt atgggtgatg tgggaagttt ggccctaggt
    51661 gggatgctgg cagctatctc tatggctctc caccaagaat ggactctctt gattatcgga
    51721 attgtgtatg tttttgaaac aacttctgtt atgatgcaag tcagttattt caaactgaca
    51781 ggtggtaaac gtattttccg tatgacgcct gtacatcacc attttgagct tgggggattg
    51841 tctggtaaag gaaatccttg gagcgagtgg aaggttgact tcttcttttg gggagtggga
    51901 cttctagcaa gtctcctgac cctcgcaatt ttatatttga tgtaagaatg gcaccctgat
    51961 gtttcagggt gtttttgtgt ttaaatacac aatgaaaatc aaagaacaaa ctagaaagct
    52021 aactttaggc tgctcaaaat atagtagatt gaaactaaaa tagtacacat ctacttctaa
    52081 aatattgtta gaaatcgatt tgactgtcct gattgatttg tcctgttctt atttcatttt
    52141 actatacagt tttgagatgg ttgatagaac tgacgaagtc agctcaaaac acggttttga
    52201 ggttgtagat aaggagaagc tgatgtggtt tgaagaggtt ttcgaagagt gtaaaaaaat
    52261 attggtcagt taaagtcaaa actcttgacc ttttctgacc aatgtagtat attatgaacg
    52321 taaggtaaat gaaagcctta ctagaacact tatttaaagt aaaatagaaa gaggtgggtc
    52381 tatgtttcat ctagaaatct tcagaagtaa agatagtcta ctcctgcttg aaaaagaaaa
    52441 accagaaata gtacgtaggg tagcgatcta gctagtctaa attttttaaa acaatggtca
    52501 aagatagtca atatcagtaa tcataactaa gtaaacaaaa agaggtaaag aatatgaata
    52561 acaactttaa taattttaat aacatggatg atttatttaa ccaattgatg ggtggtatgc
    52621 gaggatacag ttctgaaaat cgccgttact taattaatgg acgcgaagtc acacctgagg
    52681 aatttgctca ctatcgtgcg actggtcaat taccaggaaa tgcagaaact gatgtgcaaa
    52741 tgccacaaca ggcatcaggt atgaaacaag acggtgtcct tgcaaaacta ggtcgaaact
    52801 taacagcaga agcgcgtgag ggcaagttgg atcctgttat cggacgaaac aaggaaattc
    52861 aagaaacatc tgaaatcctc tcacgccgca ccaagaacaa tcctgttttg gtcggagatg
    52921 caggtgttgg taagacagca gttgtcgaag gtctagcgca agccattgtg aacggagatg
    52981 ttcctgctgc tatcaagaac aaggaaatta tttctattga tatctcaggt cttgaggctg
    53041 gtactcaata ccgtggtagc tttgaagaaa atgtccaaaa cttagtcaat gaagtgaaag
    53101 aagcagggaa tattatcctc ttctttgatg aaattcacca aattcttggt gctggtagca
    53161 ctggtggaga cagtggttct aaaggacttg cggatattct caagccagct ctctctcgtg
    53221 gagaattgac agtgattggg gcaacaactc aagacgaata ccgtaacacc atcttgaaga
    53281 atgctgctct tgctcgtcgt ttcaacgaag tgaaggtcaa tgctccttcg gcagagaata
    53341 cttttaaaat tcttcaagga attcgtgacc tctatcaaca acaccacaat gtcatcttgc
    53401 cagacgaagt cttgaaagca gcggtggatt attctgttca atacattcct caacgtagct
    53461 tgccagataa ggctattgac cttgtcgatg taacggctgc tcacttggcg gctcaacatc
    53521 cagtaacaga tgtgcatgct gttgaacgag aaatcgaaac ggaaaaagac aagcaagaaa
    53581 aagcagttga agcagaagat tttgaagcag ctctaaacta taaaacacgc attgcagaat
    53641 tggaaaagaa aatcgaaaac cacacagaag atatgaaagt gactgcaagt gtcaacgatg
    53701 tggctgaatc tgtggaacga atgacaggta tcccagtatc gcaaatggga gcttcagata
    53761 tcgaacgttt gaaagatatg gctcatcgct tgcaagacaa ggtgattggt caagataagg
    53821 ccgtagaagc tgtagctcgt gctatccgtc gtaaccgtgc tggttttgat gaaggaaatc
    53881 gcccaatcgg cagcttcctc tttgtagggt ctactggggt tggtaagacg gagcttgcta
    53941 agcaattggc actcgatatg tttggaaccc aggatgcgat tatccgtttg gatatgtctg
    54001 aatacagtga ccgcacagct gtttctaagc taattggtac aacagcaggc tatgtgggtt
    54061 atgatgacaa tagcaatacc ttaacagaac gtgttcgtcg caatccatac tctatcattc
    54121 tcttggatga aattgaaaag gctgatcctc aagttattac ccttctcctc caagttctag
    54181 atgatggtcg tttgacagat ggtcaaggaa atacagtaaa cttcaagaat actgtcgtta
    54241 ttgcgacctc aaatgctgga tttggctatg aagccaattt gacagaagat gcggataaac
    54301 cagaattgat ggaccgtttg aaacccttct tccgtccaga attcctcaac cgctttaatg
    54361 cagtcatcga gttctcacac ttgactaagg aagacctttc taagattgta gatttgatgt
    54421 tggctgaagt taaccaaacc ttggctaaga aagacattga cttggtagtc agtcaagcgg
    54481 ctaaagatta tatcacagaa gaaggttacg acgaagtcat gggggttcgt cctctccgtc
    54541 gcgtggttga acaagaaatt cgtgataagg tgacagactt ccacttggat catttagatg
    54601 ctaaacatct ggaagcagat atggaagatg gcgttttggt tattcgtgag aaagcctaag
    54661 acagagtttt gaggataaaa aagaaggagc cagctgaaaa aaactggttc cttttgaggt
    54721 acgacgggca tgtcgtacag taggttgaaa ctagaatagt acacatctac ttctaaaata
    54781 ttgttagaaa tcgatttgac tgacctgatt gatttgtcct gttcttattt cattttacta
    54841 tatatctgag gtgtaagtcc tcggtgggta cctgctaccg gtgctcccaa tagtgattcc
    54901 caagcctgac tatcgtgagg tagcggatta aaacggtctg gggatagacc gttttaagtc
    54961 tgacgctgga aataagaatc gtcagaggaa gggatagcga aatcgtggct ctacgaatag
    55021 gaacgtgata ataaggcgta tatagcggat aaggggcctc aaactctaaa gttcaaaaag
    55081 gtagtcgtag cctatatgcg taaatcacga gagcaactga atttgtctgt tcgaggatgg
    55141 ataaactatt tctcattggg aaatatgaaa agtatagtca ctagcataga tgagcgcttg
    55201 cgtactcgcc tacgagtgat tatctggaag caatggaaga agaaatctag acgattatgg
    55261 agattgctta agttaggggt tcctaaatgg atagcagata aggtatctgg ctggggtgac
    55321 cactatcaat tagtagctca gaagtcggta cttaaacgtg ctatatcaaa accagtcctt
    55381 gaaaaacgtg gactggtttc gtgtttggat tattaccttg aacggcatgc gttaaaagtt
    55441 agttgaaccg ccgtatgccg aacggcacgt gcggtggtgt gagaggggct agagattatc
    55501 ccctactcga ttttaaatca catgacgttc aaaggcatca tctgaaatcc cttgttccaa
    55561 gatgagtttt gcccattctt tagcagagaa gaggctgtgg tccttgtagt ttccgcaaga
    55621 ttcgatggtt gtccctggga catcttccca agtagtagtt tcagcgattt ccttgagcga
    55681 atccttgata acagctgcga ttttagcact ggtgtgacgt ccccacataa tcatgtggaa
    55741 gcctgtgcgg caaccaaatg gtgaacagtc aatcatgccg tcaatgcggg tacggatgag
    55801 tttggctaag aggtgctcga tagtgtgaag gccggcagta gggatagagt cttcgtttgg
    55861 ctgcaccaag cgaatatcat aattggagat gatgtctcct tttggtcctg tttcttcccc
    55921 aatcaagcga acatagggtg ctttgacaat ggtgtggtca agttcaaaac tttcgacaat
    55981 aacttctttt gacatggtaa atcctttcag ttttcttctc tcattatatc ataaaggttg
    56041 ttcctgagac agagagaaaa cctctccgag gctagagagg ttgaaatctt tacttacgat
    56101 ataagcggtc gtattggtag tatgggtcaa aggttacgtt gatacccagt ttacgaagga
    56161 cattcttgtc ttcatcagtc aagatgatgg ttgagtgggc ttcgcttcct ttgaggttgc
    56221 cgagttcttc catagcgcgg gcagcatcag gattttctgt agctgtgata gcaagtgcaa
    56281 tcaggatttc atttgaatga aggcgtggat tgcggctacc gagatgatcg attttaagac
    56341 cttggattgg cttaacaact tcaggctcga ttagttttac ttctttagcg atgtcagctg
    56401 attttttgat ggcgttgatc aaggcagcgg ctgtaggccc aaagagttct gagttcttac
    56461 cagtgacgat ttccccattt ggcaattcaa aggctagggc tggtccacca gtttcttctg
    56521 ctttttggcg cgcaacgaca gcaaccttac ggtctgcagg tgtgataccg aggtcgttca
    56581 tgagcaactc aattttcttg acggcagctt cgccaacttt ttcagctttg aagtcaagaa
    56641 ttgtttgata gtaacggcgg atgatttctt gtttagaagc ttcgacagca gcctcgttat
    56701 ctgtaatagc gaaaccaacc atgttgacac ccatatctgt cggtgaagcg tatggtgatt
    56761 ttccgagaat acgttccaac atgcgcttga gcactgggaa gatttcgata tcacggttgt
    56821 agttgacagt ggtttctcca taggtttgaa gatggaaggg gtcaatcatg ttgacatcat
    56881 caaggtcagc tgtggcagct tcataagcca agttaactgg atgatgaagg ggaagattcc
    56941 aaacagggaa ggtttcaaat ttagcgtagc cagacttgat gccattgatt tggtcgtggt
    57001 acatattgga catacacgtt gccaattttc cagaaccggg tccaggagcg gttacgacaa
    57061 tcaagttgcg actggttttg atgtagtcgt ttttgcccat gccttctggg gaaatgatgt
    57121 gatccatatc cgtcggatat cctttgattg gataatgaag ataagaatca attccgtttt
    57181 tctcaagttg attgcggaag gcatctgcag cgggttggcc agcgtattgt gtaatgacaa
    57241 cggaaccaac aaaaatccct aattcattga atttgtcaat caaacgaaga acttcttggt
    57301 cataagaaat gcctaagtcg ccacgtgctt tggaatgttc aatgttgcta gcattaatgg
    57361 caatcacaac ctcaacctgc tctttcaatt cttgcaagag cttgattttg ttgtcaggtt
    57421 cataaccagg aaggacacga gcagcgtgga aatcttctaa cattttaccg ccaaactcta
    57481 agtagagctt gccgtcaaat tggttaatgc gctccaaaat atggtcgcgt tgtaaattca
    57541 aatactgttc agaactaaaa gcttgttttt tcattttttt acctctggac tctattataa
    57601 taaaaaattg gaagttagga aactacggag ctaaaaaaga aattaaaaag attaagcaaa
    57661 cgcttgcaca aaattttaaa aagtgctatc atagactata gattatgaaa ataatgaggt
    57721 aaacagatgc aagaaaaatg gtggcataat gccgtagtct atcaagtcta tccaaagagt
    57781 tttatggata gtaatggaga tggaattggc gatttgccag gaattaccag taagttggac
    57841 tatctagcca agctaggaat cacagcaatt tggctttctc ccgtttatga cagccctatg
    57901 gatgataatg gctacgatat tgctgattat caagcgattg caacgatttt tggaaccatg
    57961 gaggatatgg atcagctgat tgcagaagct aagaagcgtg atatccgtat catcatggac
    58021 ttggtggtca atcatacctc ggatgagcat gcctggtttg tagaggcctg tgaaaatcct
    58081 aatagccctg agcgagacta ctatatctgg cgcgatgaac ccaatgacct agattctatc
    58141 tttagtgggt ctgcttggga atacgatgaa aagtcaggtc aatactatct ccactttttc
    58201 agcaagaaac agccggatct caactgggaa aatgaaaaac ttcgccagaa aatttatgag
    58261 atgatgaact tctggattga taaaggtatt ggtggtttcc gtatggatgt tattgacatg
    58321 attggcaaaa ttcctgacga gaaggtagtc aataatggtc ctatgctcca tccctatctc
    58381 aaggaaatga atcaggcgac ctttggagat aaggatctct tgacagtagg ggagacttgg
    58441 ggagcaacgc cagagattgc caagctctac tctgatccaa aggggcaaga attgtctatg
    58501 gtcttccagt ttgaacatat cggtcttcag tatcaggaag gtcagcctaa atggcactat
    58561 caaaaagagc tgaatatcgc taagttaaaa gaaatcttca acaaatggca gacagagtta
    58621 ggagttgagg acggctggaa ttccctcttc tggaacaacc atgacctccc tcgtattgtc
    58681 tcaatatggg gaaatgacca agaataccgc gaaaaatctg ccaaagcctt tgcaatcttg
    58741 cttcatctta tgagaggaac tccttatatc taccaaggtg aggagattgg gatgaccaac
    58801 tatccgtttg aaacactaga tcaagtagaa gatattgaat ctctcaacta tgcgcgtgag
    58861 gctcttgaaa aaggtgttcc gattgaagaa atcatggaca gtatccgtgt tattggacgt
    58921 gacaatgccc gtacccctat gcaatgggac gagagcaaaa acgctggttt ctcaacaggt
    58981 caaccttggt tggcggttaa tccaaattac gagatgatca acgtccaaga agcgctggca
    59041 aatccagatt ctattttcta tacctatcag aaactggtcc aaattcgcaa ggagaatagc
    59101 tggctaattc gagctgactt tgaattgctt gatacggctg ataaggtctt tgcttatata
    59161 cgtaaggatg gcgaccgtcg cttcctagtt gtggctaact tgtctaatga agagcaagac
    59221 ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa acaccctagc tcaagaagtc
    59281 tttgaaaaac aaatcttagt tccatgggat gctttctgtg tggaattact ataaatattt
    59341 tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag ggaggactgt ataaaagaca
    59401 gaaatccttt gttttttata accaaggttt ataaactttc attctcgaaa ttcaattaac
    59461 tttacaaatt cccactatta aggagaaaga aaatgaacat aaagaagcgt gtccttagtg
    59521 caggcctgac ttttgcatct gctttgcttt tagctgcttg cggccaatca ggttcagata
    59581 caaaaactta ctcatcaacc tttggtggaa atccaactac atttaactat ctattagact
    59641 attacgctga taacatagtc aattgaaaca agaacaggac aaaagagcct cgtaaaaggt
    59701 attgcaactg ggtaatacct ttttgaggtg ctttttgata tgagcccatg ttttctcaat
    59761 aggattgtac tcaggtgagt agggaggaag aggtaaaagt ttacgcccaa actcctcgca
    59821 taaaagttct aacttaccca ttctatggaa tcttacatta tccataataa taaccgatgg
    59881 tgtgtttaat gttggtaaga gaaaattctg aaaccaagct tcaaaaaagt cgctcgtcat
    59941 cgtctcttcg taagtcattg gagcgattaa ttcaccattt gttagacctg caaccaaaga
    60001 aatcctctga tatcttcttc cagatacttt gcctcttctt aactgacctt ttaatgagcg
    60061 accatattct cgataaaaat aagtatcgaa tcctgtttcg tcaatctaaa caggtactag
    60121 gtgctttaaa ctattaaaat tcttaagaaa taaggctact ttttctgggt cttgttcata
    60181 gtaggtgtgg ttcttttttt cgagtgtagc ccatagcttt gagcgcatag tggatggtag
    60241 ttggatgaca gccaaattca gaagctattt cagtcaaata agcgtctgga ttgtcagtaa
    60301 gatagttttt aagtctatct ctatcaactt ttcttggttt tgttcctttt acttggtggc
    60361 ttagctctcc tgttttctct tttagcttta accagccata aatagtatta cgtgagattt
    60421 ggaaaacgtg tgatgcttct gttatactac ctgttcgctc acaataagag agaacttttt
    60481 tacgaaaatc tattgaatat gccataaaaa gattatgcca cattgtgtac tatagtagat
    60541 tgaaactaga atagtacacc tctgcttcta aaacattgtt agaaatcgat ttgactgtcc
    60601 tgatcgattt gtcctgttct tatttcattt tactatattt ttgtttcgcg ggaagtctac
    60661 taagatattt aaagatgcag atagtaaaaa aagatgtaga cattaccgta aaaaagtgat
    60721 ataatcgtat gatgttcaat gtataggtgt taatcatgag tagacgtttt aaaaaatcac
    60781 gttcacagaa agtgaagcga agtgttaata tcgttttgct gactatttat ttattgttag
    60841 tttgtttttt attgttctta atctttaagt acaatatcct tgcttttaga tatcttaatc
    60901 tagtggtaac tgcgttagtc ctactagttg ccttggtagg gctactcttg attatctata
    60961 aaaaagctga aaagtttact atttttctgt tggtgttctc tatccttgcc agctctgtgt
    61021 cgctctttgc agtacagcag tttgttggac tgaccaatcg tttaaatgcg acttcgaatt
    61081 actcagaata ttcaatcagt gtcgctgttt tagcagatag tgagatcgaa aatgttacgc
    61141 aactgacgag tgtgacagca ccgactggga ctgataacga aaatattcaa aaactactag
    61201 ctgatatcaa gtcaagtcag aataccgatt tgacggtcaa ccagagttcg tcttacttgg
    61261 cagcttacaa gagtttgatt gcaggggaga ctaaggccat tgtcctaaat agtgtctttg
    61321 aaaatatcat cgagtcagag tatccagact acgcatcgaa gataaagaag atttatacca
    61381 agggattcac taaaaaagta gaagctccta agacgtctaa gaatcagtct ttcaatatct
    61441 atgttagtgg aattgacacc tatggtccta ttagttcggt gtcgcgatca gatgtcaata
    61501 tcctgatgac tgtcaatcga gataccaaga aaatcctctt gaccacaacg ccacgtgatg
    61561 cctatgtacc aatcgcagat ggtggaaata atcaaaaaga taaattaact catgcgggca
    61621 tttatggagt tgattcgtcc attcataccc tagagaacct ttatggtgta gatattaatt
    61681 attatgttcg tttgaatttt acctcatttt tgaaattgat tgacttattg ggaggggtag
    61741 atgttcataa tgatcaagag ttttcagctc tacatgggaa gttccatttc ccagtaggga
    61801 atgtccatct agactctgag caggctctag gttttgtacg tgaacgctac tcactagccg
    61861 atggagaccg tgaccgtggt cgcaaccaac aaaaggtgat tgtggctatc cttcaaaaat
    61921 taacgtcaac cgaagcactg aaaaattata gtacgatcat taatagcttg caagattcta
    61981 tccaaacaaa tatgccactt gagactatga taaatttggt caatgctcag ttagaaagtg
    62041 gagggaatta taaagtaaat tctcaagatt taaaaggtac aggtcggacg gatcttcctt
    62101 cttatgcaat gccagacagt aacctctatg tgctggaaat agatgatagt agtttagctg
    62161 tagttaaagc agctatacag gatgtgatgg agggtagatg aaatgataga catccattcg
    62221 catatcgttt ttgatgtaga tgacggtccc aaatcaagag aggaaagcaa ggctctcttg
    62281 gcagaatcct acagacaggg ggtgcgaacc attgtctcta cctctcaccg tcgtaagggc
    62341 atgtttgaaa ctccggaaga gaagatagca gaaaactttc ttcaggttcg ggaaatagct
    62401 aaggaagtgg cgagtgactt gatcattgct tacggggctg aaatttacta cacaccagat
    62461 gttctggata agctggaaaa aaagcggatt ccgaccctca atgatagtcg ttatgccttg
    62521 atagagttta gtatgaacac tccttatcgc gatattcata gcgctttgag caagatcttg
    62581 atgttgggaa ttactccagt cattgcccac attgagcgct atgatgctct tgaaaataat
    62641 gaaaaacgcg ttcgagaact gatcgataag ggctgttaca cgcaagtaaa tagttcacat
    62701 atcctcaaat ctaaactttt tggcgaacgt tataaattca tgaaaaaaag agctcagtat
    62761 tttttagagc aggatttggt ccatgtcatt gcaagtgata tgcacaatct agatggtaga
    62821 cctcctcata tggcagaagc atatgacctt gttacccaaa aatacggaga agcgaaggct
    62881 caggaacttt ttatagacaa tcctcgaaaa attgtaatgg atcaactaat ttaggagaaa
    62941 tgatgaaaga acaaaacacg atagaaatcg atgtatttca attattaaaa accttgtgga
    63001 aacgcaggct aatgatttta ttagtggcac ttgtgacagg tgcgggggct tttgcatata
    63061 gcacttttgt tgttaagcca gaatatacga gtaccacgcg aatttacgta gtgaatcgca
    63121 atcaagaaga caagccgggg ctgacaaatc aggatttgca ggcaggaact tacctggtaa
    63181 aagactaccg tgagattatc ctttcgcatg atgtattgga aaaagtagcg acaaatttga
    63241 agttggatat gccagcaaga gcgttagcca gcaaagttca agtgactgta ccagctgaca
    63301 ctcgtatcgt ctcaatctct gtcaaggata aacagccaga ggaagccagt cgcatcgcta
    63361 attctctacg agaagttgct gcagaaaaga tcgtcgctgt aacgcgagta tctgatgtaa
    63421 cgacacttga agaagcgcga ccagctacga ctccctcttc tccaaatgtt cgacgcaatt
    63481 ccttgtttag ttttcttgga ggagcagtcg taacagtaat tgctgttctt ttgattgagt
    63541 tgctcgacac tcgtgtgaaa cgtcctgaag atgtcgaaga tgtactgcga attccacttt
    63601 tagggctcgt tccagatttg gacaaaatga aataggagga agttatgcca acgttagaaa
    63661 tctcacaggc aaaattggat tttgtaaaaa aggcagagga atattataat gctttgtgca
    63721 cgaacctaca gttaagtgga gataatttaa aagtattttc tatcacttct gtgaaactag
    63781 gagaaggaaa atcaacgact tccaccaata tcgcttgggc ttttgcgcgt gcaggttaca
    63841 aaacgctgct gattgatgga gatattcgca attctgttat gtcaggtgtc tttaaagcaa
    63901 gggataagat tacaggcctg acagaatttt tatcaggaac tacagaccta tcacaagggc
    63961 tttgtgatac caatatcgaa aatctctttg taattcaggc tggttctgtg tcaccgaatc
    64021 cgacagctct tcttcaaagt aagaatttca gtacaatgct tgaaaccttg cgtaaatatt
    64081 ttgactacat cattgtagat actgctcctg tcggtgtcgt gattgatgca gctattatta
    64141 cgcgaaaatg cgatgcttct attttagtga cggaggcagg tgaaataaat cgacgggata
    64201 ttcaaaaagc aaaagaacag ttggaacaca cagggaagcc gtttttggga gttgtgttga
    64261 ataaattcga tacttcagta gacaaatatg gttcttatgg aaattatgga gattacggga
    64321 aaaataaaaa ataggtcggg gggatagaga tgaatggaaa aatagtaaag tcttcattgg
    64381 tcataatcca gagttttctt gttattttat tgacttatct acttagtgct gtgagagaag
    64441 cggagattgt ttcaacaaca gctattgcac tttatatcct ccattatttt gtcttttata
    64501 tcagtgatta tggacaggct ttctttaaaa ggggatattt gattgaactt gtccagacat
    64561 tgaaatatat cctattcttt gcactagcga ttggtatttc taattttttc ttagaggatc
    64621 gatttagtat ttccagacga ggcatgattt acttcctcac attacatgct ctcttagtct
    64681 atgtgctaaa cctatttatc aagtggtatt ggaagcgggc ttatcccaac tttaaaggaa
    64741 gtaagaagat tctcctactt acagcaactt ctcgtgtcga aaaggtactg gatagattaa
    64801 tagaatcaaa tgaggttgtt ggggagttgg tagccgtcag tgtcttagat aaaccagatt
    64861 ttcagcatga ttgtttaaag gtagtagcag agggggagat agtaaacttt gcgactcatg
    64921 aggtggtcga tgaagtcttt atcaatcttc caagtgaaaa atacaatatt ggagagcttg
    64981 tctctcagtt tgaaacgatg ggaattgatg caacagttaa tctaaatgcc tttgatcgta
    65041 gtttggcacg taacaagcaa attcgtgaga tggcaggatt aaacgttgtg actttttcta
    65101 caacatttta taagactagt catgtaattg ctaagcggat tattgatatc gtgggtgcat
    65161 tggtagggct gatactatgt ggtctagtca gtgttgtact ggttcctttg attcgaaagg
    65221 atgggggctc tgctattttt gctcagacgc gtattggaaa aaatggtcgc tacttcactt
    65281 tttacaagtt ccgctccatg tgtgtagatg ccgaggcgaa aaaaagagaa ctcatggaac
    65341 aaaataccat gcagggtgga atgtttaagg tggacgatga tccgcgtatc acgaaaattg
    65401 gtcgttttat aaggaagact agcttggacg agttgccaca gttttataat gttttaaagg
    65461 gagatatgag tttggttggc acacggccac caacagtgga cgaatatgag cactataccc
    65521 cagaacaaaa acgtcgtcta agttttaaac ctggtataac aggcttatgg caggtcagtg
    65581 gacgaagtga aatcaaaaat ttcgatgaag ttgtcaaatt agatgtggct tatatagatg
    65641 attggacaat ttggaaagac attgaaattt tattgaagac agttaaagta gtatttatga
    65701 gagatggagc gaaatagttt acttttgttt cagactacta ggagaaaaat gaagaagtca
    65761 gtttatatca taggttcaaa gggaattcct gccaagtatg gaggatttga aacctttgtt
    65821 gagaaattaa cagaatatca aaaagatggt aacatccaat actatgttac ctgcatgcgc
    65881 gaaaattcgg caaagtcagg atttacagca gatacatttg agtacaacgg tgctatttgt
    65941 tacaacattg atgtgcctaa tattggtcct gctagagcca ttgcctacga cattgcagcg
    66001 gtcaataagg ctattgaatt ggctaaagaa aacaaggacg aggctcccat tttttacatt
    66061 ttagcttgtc gtatcgggcc ttttatttct ggacttaaga aaaaaattcg ttcgatcgga
    66121 ggccgtttgc tggtaaatcc agatggtcat gagtggcttc gagctaaatg gagcttgcca
    66181 gttcggaagt attggaaatt ttcggaacag ttgatggtta aacatgcaga tttattagtc
    66241 tgcgatagca aaaatatcga aaaatatatt cgagaggact ataaacagta tcagcccaag
    66301 acgacctata tcgcttatgg tacagatact accccttcaa gtctgaaatc agaagatgcc
    66361 aaagttcgaa actggtatcg tgaaaaggga gtaagcgaaa atggctatta tctagtggtg
    66421 ggacgattcg ttcccgaaaa caactatgaa accatgattc gtgaatttat caagtctaag
    66481 tccaataagg actttgtcct tattacaaat gtggaacaga ataaatttta cgatcagttg
    66541 ctcaaggaaa caggtttcga caaggatcta agagtcaaat ttgtgggaac agtctatgac
    66601 caagaattgc tcaagtatat ccgtgaaaat gctttcgcct atttccatgg acatgaagtt
    66661 gggggtacca atccatcgct tcttgaagct ttagcatcca ctaaactcaa cttgttgttg
    66721 gatgtcggct ttaaccgtga agttggtgaa gacggagcca tttattggaa aaaagatgag
    66781 ctagcgcatg taatcgaaga agtggaacga tttgatgaag gtgatatttc ggaattagac
    66841 gaaaagtcta gccaacgaat tgcggatgca tttacgtggg aaaagattgt gtcagattat
    66901 gaagaagtgt ttaaaggata aggaatgaaa cggattttat acttgcatgc tggtgcagaa
    66961 atgtatggag cagataaggt tttattggag ttgatcaaag gattggattc caaagaattt
    67021 gagacgcacg ttatcttgcc aaatgacggt gttttagtcg aggctttgcg ccaggttgga
    67081 gctcaggtca gcgtgttgga ttatccgatt ttacgtagaa aatactttaa tcctaagggg
    67141 atttttgaat atctgaaatc ctatcatcgc tactctcaaa aaatcgctca atatgtgcgt
    67201 gagaatggga tagttcttgt tcataacaat acaacagccg ttctggaagg gatttatcta
    67261 aagagaaaag taaaacttcc cttgatctgg catgttcatg agattattgt taagcctaag
    67321 gccatttcag attttatcaa cttcttgatg ggacgttatg caaataaaat cgtaacagta
    67381 tctcaagcag tggccagtca tgtcaatcag tctcccttca tcaaagaagg gcaggtccag
    67441 gttatctata atggagtgga caatgcggtc tatcatccga tgccagcaag cacagtgcgt
    67501 gaacaatttt ctatcccgga agaggctctt gtcattggta tggttggtcg cgtcaacgct
    67561 tggaaggggc aaggagattt tctagaagcg gtgacgccga ttttggagca gaatcccaat
    67621 gccatcgctt ttctggctgg aagtgccttt gctggtgaag agtggcgagt tgaagaactc
    67681 gagtctaaga ttgccaaatc aagtgtagtc tcacaaatca aacgaattga ctattatgag
    67741 catacgactg agctttataa tatgtttgat atctttgttt taccaagtac caatcctgat
    67801 cccctaccaa cagtggtact agaggcgatg gcatgcggca aaccagtagt cggctatcgt
    67861 catggtggtg tttgcgaaat ggttgatgaa gggacaaatg gcttactggc cactccaaat
    67921 cagcctgctg aactatcgaa agtcattcaa gaattggtgg agaatccaga gaaaagaaac
    67981 caatttggcc aagcatcagt agaaagacaa agagagttgt tttctttaga tagttacatt
    68041 aagaacttct cggagttgta taaaacagat agaaaagatt agttatgaat aaaatagatt
    68101 ttgttgttac ttgggttgat gggaatgacc ctgtatggaa agaaaaaaaa tcaaggtatg
    68161 atggctcggt cagtacttct aaacagagta tgaactcggt caaagcttac cgagaatggg
    68221 gaacctttaa atactggttt agaggagttg aaagatttgc cccttgggtc aataaggtct
    68281 acctcgtgac cgaccagcaa agaccaagct ggttagatat aaacagtgaa aaattggtct
    68341 tggtagatca tacagagatt atctgtaatg actgcctacc agttttttct gccaatccga
    68401 tcgaaagtaa tatccatcga attcctggtc tctctgagca ctttgtcttt tttaatgacg
    68461 atatgtattt gacggctcca gttgaaccga cagatttttt ctcagaggat ggtttaccca
    68521 aatataatac ggctctttct ccgattattc ctgaaagata tggaacagga aattttcaga
    68581 taaatgacat ggaaattgtc actagctatt tcagtcgaaa tgaaattttg aagaatgggc
    68641 aattctttga tccaaagcag ggattaaaaa gtattgttaa gtcgctacta tacagaaata
    68701 gtcagtttat ctgtggtttc tgggagagtc atctgcccta tcctctacta aaatcaacga
    68761 tggatttgat atgggaaaag gaaaaagctg tcttggggag aacctcagcg agtcgcttta
    68821 gaaatccgtc tgataccaat gtttggctct ttaagtattg gcagattgct agtggtcaat
    68881 acgctgtcgg aaatcctaag ttggggagac tcttttcttt ggataatgcc ggaccagatt
    68941 tttggaactt actaaattct ggcaaataca aaattatgtg tatcaatgat gtgtatgata
    69001 ttaaggatga agaaaaagta atgcaagaat ttattgctgc aatgaaaaat cttttgcctg
    69061 ataaaagtac atttgaatta taaaaaagga gtgggaatat gccatcagtt tgtgctttag
    69121 ttgtgacata taatcgttca aaatatctgc aaaaggcttt ggaaggtatt ttgaatcaac
    69181 aacaagaaat ttcgggaatt ttaatttata acaataatgc tacagataat actgaagaaa
    69241 ttcttatgaa attcggttat gttgattcaa aaggcgataa gataaaagaa aattatcttt
    69301 attcgaccga aaaagatgga aaacacttct actattacca taatgacgaa aacctaggag
    69361 gagctggagg ctttgcaaat ggaattcgat taatttcaga gcttgattat gattatgttt
    69421 ggattatgga cgatgatgtc tatccggaac ctaattgttt atccgaaatt atgaaacaaa
    69481 tgagtgtcca aaatgtacag gtaggtatcc cgaatcgtac agatgaaaat tttgatgacc
    69541 gtgccattat cggttttgat tttgatgact atcataaatt ttggacggaa atgagaaaaa
    69601 cagtaacata cggtcccttt gatgaagaag cgataaaagt ggttgatatg ccatttgaag
    69661 gaccagttgt tgaaatggca ttgcttcgta aagttggtat tcctgatagt ggctttttta
    69721 ttgagtacga tgattcggac tttgcacaac gcctacaaca gtattcagat ataatttttg
    69781 caacaaaagc acaattgcat cgtcaacttg ctgtaaaagt ggatccaagc gaggtaaaaa
    69841 aagtggaacc ttataattgg agaaattact ataaaattcg aaataatatt attttcgata
    69901 agcgatatgg aaaaaattgg aaagtacgtc aattgagtcc tttaattcta attgctcacc
    69961 atattgtgat tgctattcgc catcagcatt taaaacataa cttgccaatt atttggaagg
    70021 gtttttggga tggagttttt caacgaatgg ggaaacgagt agaccccaat tattaaaagg
    70081 agaaaaaaat gtctgattta ctgttgagtt tcattatgcc gacctataac tctgcagaat
    70141 acttagcaga tacaatggat agtttagtag cctctatagg tgattataat catttagtgg
    70201 aaattatttg tgttgacgat ggctcatggg ataatacagt tactatttta gaaggataca
    70261 agtctattta tgataatttg attattataa gaaatgagca tggtggggtt agtcaggcta
    70321 gaaatacagc tttagatata gtttctggga aatatatcag ttttgttgat agtgatgatt
    70381 tgtatgagaa agatttttta aatactttta tttcattgga caagaatttt gatttccttt
    70441 tcactgatgt gggtggactt aaggatgaaa ttagtttcca agaaattaat gaaaaggaaa
    70501 aattaaaaat ttttaaaaat aattttaatt taggtgagta tacaattcat cctggaatag
    70561 ctgggaaatt ttttagaaca agtttaatta atgatattca attgagattt aacacgcaac
    70621 tgtcatttgc tgaggatatt ttatttaatt ttacattgct gacagcctca agacatgtga
    70681 ttctatcccc tgtaaatttt tatcatgtca atgggactca tagtttaatg tactacaatg
    70741 aaaaaaattt aaaagggcag attgtatttg tagatagaat acgtcaaatt ttaaaaggat
    70801 actctgaatc atcggaaata gtcttaatag agaattttat tatcttgaag gctatgactg
    70861 tttatattga tcgttatttt ggaccattgt ggttgaatgg aacttattca ttgaatgaag
    70921 catcaaaatt aatgaaatct acaattgagg ataatgactt ttcaaaagct tttaatagta
    70981 atcgcttaga ttattctatt ggaaatcgtt atgttgtttt cagaaaattg ttgaggttta
    71041 gacagtacaa actatgtttg ttatacaatc gtataatgga taaaattaag ggatatgaga
    71101 ggtttaggaa acaatgatta aactttcaat tcacgatata tatcgttatt ttctctacct
    71161 catttttttt atgaacttat tattctttaa tattgtttca gacctaacct atacaatcca
    71221 aaatttttcg gtttatttga catttttatt gatgggaatg tatttactac aaagacgaat
    71281 atcaaagtta acaattttca cgtcaattac agttctatta tttttcttat tgataatgtt
    71341 caatttatat agacaaggac tacctgttaa tggctttttg tcttttaata gtaaaatata
    71401 tttgttgaga aatttcagtt ttattctact agtctttcca atatcagaga tattaaagcc
    71461 aaagtatagt ttaaattttt taaaagtagt ttttgtattt ggaattcttg caattttatt
    71521 tcgtactttt atttggatga gttataatta tgctggttta aatatcgctc cgggtataat
    71581 tgaagaaaga ggtgtgaatt ggacacgtta tggagcggtt cgtctacaag cccttttttt
    71641 ggatggctac gttttggcat atttgttatg taagttatta ataagtgatt caaagaataa
    71701 agtatcttat agtctacttt tgttgattac tttgttctat gagggagtga tttatgcttc
    71761 taggtcacaa cttattggtt tcagtataat gtttattgca atttatttat taaaaaataa
    71821 gaacttacta aataaattac tcagtttttt atcactcagt ttagcttctt ttgcaattct
    71881 actgagtcca tattatgaaa aatttattga tagtttctct gtatcaaata gcgattatgg
    71941 tgcaggtacg atggttcgta ttgttggaag gagatactat caagaaatat ggaatcaaaa
    72001 taaactttta ggttttgggc caatctcaga tggcaatatt tttgctggtt ggaagtatta
    72061 tttatctgat ttaggtatta ttagaatgct ctatcaattc ggaattatag gttttatcat
    72121 ttgtttatta cctattttgt atggatgttt agttggtttc aagaatagat tacactttaa
    72181 aggtatgctg ttattttgtc tttctctatt tgtattagta actagctttg cttcgcaaaa
    72241 tttatatgat tataatagaa ttatgcttct tccgttgtta ttagggttag caaatgctgt
    72301 ttcatcaact caagcagata aggatatggt atgaaagttc ttaaaaatta cgcctataat
    72361 ctctcttatc aactgttgct gattattttg ccggttatta ctactcctta cattactcgg
    72421 gtgtttagct cggatgactt gggtacctat ggttatttca actcaatcgt cacctatttt
    72481 atcttattgg caactttagg agtagctaat tatggtacca aggaaatttc agggcatcga
    72541 aaagaaattc gaaggaattt ctgggggatt tataccctac agctaggagc gactatttta
    72601 tccggtaccc tctatgctat actatgtctg agtttgccat ctatgcaaga ttcagttgcc
    72661 tatatcttag ggtttagttt gctttcaaag ggattagata tttcttggtt atttcaaggt
    72721 ttggaagact tccggaagat tattgtgcga aatattacag tcaaacttgt cggtgtaatc
    72781 tcaatcttct tgtttgtaaa atctgctaaa gacctttatc tctatgtttt tttactaacc
    72841 atatttgaac tgttaggcca gttgagtatg tgggtgcctg ctcgagaatt tattggaaag
    72901 ccacatatag atattaacca cgcaaagaag catctaaagc ctgtcattct tctctttctt
    72961 cctcaaatcg ccatttcctt gtatgtgacc ttggatagaa ctatgcttgg agctttagct
    73021 tcaaaaacag atgtagggat ttatgatcag gctttaaagc tagtaaacat cttgttgact
    73081 ctagtaacct cactagggag tgttatgttg ccacgagtgt ctagtcttct atcacaaagt
    73141 gattataagt ctgtgaagaa aatgtaccaa atgtcctttt taatttataa ttcagtcatt
    73201 tttccaatta ttgctgggat gttgatcgtg aatgacgact ttgttcaatt ctttttagga
    73261 agggatttcc aagatgcccg ctatgcaatt gcaattatga tgtttagaat gttctttatt
    73321 ggatggacca atatcatggg aattcaaatc ctcatccccc ataataaaaa taaagaattt
    73381 atgatttcga ccactgttcc cgctattgtc agtgtcggat tgaacctcat cttcttaccg
    73441 aatctaggtt ttatcggggc agcgattgtg tctgtgttga cagaagcttt ggtatggggg
    73501 attcaacttc acttcacatg gtcttatctt aaagaggtac caattattgg ctcaatgatc
    73561 aagattgtta ttgcttcggg gatcatgtat gctttcttgg tatctatgaa gtccgttgtt
    73621 catgtttcac ctgctattaa tgttgctctg tatgctttgc taggtggagt gatttatgta
    73681 gccttgattt tgcttttcaa ggtggtgaat ttgaaagagt tgaaacagga actattaaaa
    73741 aatagggaga tttaatatgt acgactattt aatcgttgga gctggtttgt ctggagctat
    73801 ttttgctcac gaagctacaa aacgtggaaa aaaagtaaaa gtgattgata aacgcgatca
    73861 cattggaggg aacatatact gtgagaatgt agaaggtatc aatgttcata aatatggtgc
    73921 ccatatcttc catacttcta ataaaaaagt ttgggactat gtcaatcaat tcgctgaatt
    73981 taacaactat atcaattcac ctgtcgcgaa ctacaaagga agtctttata atcttccttt
    74041 caatatgaat actttctatg ctatgtgggg gacaaaaact ccacaggaag tgaaagataa
    74101 gattgctgag cagacggctg atacgaagga tgttgagcca aaaaatctgg aagaacaagc
    74161 tatcaagttg attggtccgg atatctatga aaagttgatc aagggctata ctgaaaagca
    74221 atggggacgc tcagcaacgg aacttcctcc atttatcatt aaacgtcttc cagttcgtct
    74281 aacatttgat aataactatt ttaacgaccg ttaccaagga attcctattg gtggttataa
    74341 tgtaattatc gaaaacatgc ttaaagacgt tgaagttgag cttggtgttg atttctttgc
    74401 tcaccgtgaa gagttagaag tatcagctga aaaagttgtc ttcacaggaa tgatcgacca
    74461 gtattttgac tacaaacacg gggagttaga ataccgtagc cttcgctttg agcatgaaat
    74521 tttggacgag gaaaattatc aagggaatgc tgtagtgaac tatacagagc gtgagatccc
    74581 ttatactcgt atcatcgaac acaaacattt tgaatatgga acgcagccaa agacagttat
    74641 cacgcgtgaa tatccggctg actggaagcg tggagacgag ccctactatc cgatcaacga
    74701 tgagaaaaat aatgctatgt ttgctaagta ccaagaggaa gcttcaaaga atgataaagt
    74761 tatcttctgt ggacggttag cagattataa atattatgat atgcatgtag ttattgagcg
    74821 agcgcttagc gtagtagaag aagaatttag taattgaaaa acaacggaga aaggttattc
    74881 cattatgaaa ggtattattc ttgcaggcgg ctcaggtacc cgactgtacc cccttacacg
    74941 agctgcatca aaacaactga tgccggttta tgataaacct atgatttatt atcctttgtc
    75001 gacattaatg ttggctggaa ttaaagatat tttgattatc tcaactcctc aagatctacc
    75061 tcgttttaag gatttacttt tagatggttc cgagtttggt atcaagcttt cttatgccga
    75121 gcagcctagt ccagatggac tagcgcaagc ctttatcatc ggtgaaaaat ttatcggtga
    75181 cgatagtgtt gctttaattt taggcgataa tatctatcat ggacctggtt tgagcaaaat
    75241 gcttcaaaag gcagcccaga aagagaaagg tgcgactgtt tttggctacc aagtgaagga
    75301 tccagagcgt tttggtgtag tcgagtttga tacagacatg aatgccattt ccatagaaga
    75361 aaaaccgaag gatcctcgct ctaactatgc tgtgactggt ctgtatttct atgataatga
    75421 tgttgtagaa attgctaaag gcattaaacc aagtgcacgt ggcgaattag aaattacaga
    75481 tatcaacaag gcttacttgg atcgtggtga tttgtctgtt gaactcatgg gacgtggttt
    75541 tgcttggttg gatactggca ctcatgaaag tttactagaa gcttctcagt atatcgaaac
    75601 agttcaacgg atgcagaatg ttcaagttgc aaacttggaa gaaattgcct atcgtatggg
    75661 ctatatcagt cgtgaagatg tactagagtt ggcacaacct ctgaagaaga atgaatacgg
    75721 acgatatttg ctccgtttga ttggagaagt ctagatgaca gataattttt ttggaaaaac
    75781 acttgcagtt cgtaaaattg atgccatttc aggtatgtta gagtttgata ttcccgttca
    75841 tggagacaat cgtggttggt ttaaggaaaa tttccagaag gaaaagatgg tgccacttgg
    75901 ctttcctgaa agcttctttg ctgaagggaa actgcaaaat aacgtcagct tttctcgcaa
    75961 aaatgttctt cgaggcctcc atgctgagcc ttgggacaag tacatctctg ttgcagataa
    76021 tgggaaggtt ctaggaacat gggttgattt gcgtgagggt gaaacttttg ggaatattta
    76081 ccagacagag attgacgcta gtaagggaat ctttgtccct cgtggcgtag ccaatggatt
    76141 tcaagtccta tctgatacag tttcttatag ttatctggtt aatgactatt gggcgcttga
    76201 actcaaacct aagtatgcat ttgttaacta ctctgaccca gaattaggaa ttgagtggga
    76261 aaatctggaa gaagcagagg tatctgaagc agacaaacat catcccctac ttaaggacgt
    76321 gaaacctttg aaaaaagaag atttggaata aggaaataat atgactaaat ataaaaacat
    76381 catcgtgaca ggtggggctg gttttatcgg ttctaacttt gtccactatg tttacaataa
    76441 ctttccagat gtgtatgtga cagtgctgga caagctgact tatgcaggta atcgtgccaa
    76501 tattgaagaa attttaggcg accgtgttga gttagtcgtt ggagatattg ctgatgcagc
    76561 cttggtagat aagttagcag ctgaagcgga tgccattgta cactatgcgg cagaaagcca
    76621 caatgacaat tcgcttaatg acccctcgcc atttatccat accaacttca tcggaactta
    76681 tacactcttg gaagcggctc gtaaatacga ccttcgtttc caccatgtgt cgactgacga
    76741 agtctatggg gatctgccgc tgcgtgaaga tttaccaggt catggggaag gaccaggtga
    76801 gaaatttacg gctgaaacca agtacaatcc aagctcgcct tactcatcga ctaaggcggc
    76861 ttcagacttg attgtcaaag cttgggtacg ctcatttggc gtcaaagcga ctatttccaa
    76921 ctgttccaac aactatggtc cttaccagca tattgagaag tttattccac gacaaatcac
    76981 caatatcttg agcggtatca agccaaaact ctatggtgaa ggtaaaaacg ttcgtgactg
    77041 gatccatacc aatgaccatt cttcaggagt ttggacaatc ttgacaaaag ggcaaatcgg
    77101 tgaaacctac ttgattgggg ctgatggtga gaagaacaat aaggaagttt tggaacttat
    77161 ccttaaggaa atgggacaaa ctgcggatgc ctatgatcat gtgactgatc gtgcaggaca
    77221 tgaccttcgc tatgcgattg atgcaagcaa gctctgtgat gagttggggt ggaaacctga
    77281 atttaccaac tttgaagctg ggctcaaggc aacaatcaag tggtatacag ataaccaaga
    77341 atggtggaaa gcagaaaaag aagctgttga agccaattat gctaagactc aggagattat
    77401 tacagtataa aaagcaggaa atagctactt tttattgcta tattgggaag agttacatat
    77461 tagaaaggcc tagagatgat tttaattaca ggggcaaatg gccaattagg aacggaactt
    77521 cgctatttat tggatgaacg taatgaagaa tacgtggcag tagatgtggc tgagatggac
    77581 attaccgatg cagaaatggt tgagaaagtt tttgaagagg tgaaaccgac tttagtctac
    77641 cactgtgcag cctacaccgc tgttgatgca gcagaggatg aaggaaaaga gttggacttc
    77701 gccatcaatg tgacggggac aaaaaatgtc gcaaaagcat ctgaaaagca tggtgcaact
    77761 ctagtttata tttctacgga ctatgtcttt gacggtaaga aaccagttgg acaagagtgg
    77821 gaagttgatg accgaccaga tccacagaca gaatatggcc gtactaagcg tatgggggaa
    77881 gagttagttg agaagcatgt gtctaatttc tatattatcc gtactgcctg ggtatttgga
    77941 aattatggca aaaacttcgt ttttaccatg caaaatcttg cgaaaactca taagacttta
    78001 acagttgtaa atgaccagta cggtcgtccg acttggactc gtaccttggc tgaattcatg
    78061 acctacctag ctgaaaaccg caaggaattt ggttattatc atttgtcaaa tgatgcgaca
    78121 aaagacacaa catggtatga ttttgcagtt gaaattttga aagatacaga tgtcgaagtc
    78181 aagccagtag attccagtca atttccagcc aaagctaaac gtccgctaaa ctcaacgatg
    78241 agcctggcca aagccaaagc tactggattt gttattccaa cttggcaaga tgcattgcaa
    78301 gaattttaca aacaagaagt gagataagta gtagaatgat tttctagtct aataaaagag
    78361 gcagataatg aactccaaag gagcttaaga tgtacgatta tcttgttgtt ggtgctggtc
    78421 tctttggtgc agtctttgcc catgaagcag ccttaaaagg aaaaaagtaa aagttattga
    78481 aaaacgaaat catatcgcgg gtaatatcta tactcgtgaa gaggaaggaa ttcaagttta
    78541 tcaatatggt gctcatatct tccatacttc tgataaggag atctgtgatt atgtaaatca
    78601 gcttgcagag tttaaccgtt acacaaattc tcctgttgca aactataagg gtgagattta
    78661 taaccttcct tttaatatga atactttcaa taaactctgg ggagttgtaa cgccagcagg
    78721 agcacaagct aagattgagg aacaacgtgc tattttaaat ggtaaaactc ctgaaaattt
    78781 ggaagaacag gagatttctc ttgtaggtac agatatctac gaaaaattaa tcaaagacta
    78841 tacagagaaa cagtggggca aaccaactac tgaacttcca tcctttatta ttcgccgttt
    78901 accagtacac ctgacctatg ataacaacta ttttaacgat acctatcaag ggattccaat
    78961 tggtgattat aatgttatca tcgaaaatat gctgaaggat gtagaagtag aacttggagt
    79021 gaactttttt gccaatcgtc aagaattaga ggcttctgct gaaaaggttg tctttacagg
    79081 aatgattgac caatactttg attataaaca tggtgagtta gaataccgta gtcttcgttt
    79141 tgatcatgaa gttctagatg aggaaaacta tcaaggaaac gcagttgtaa actatacaga
    79201 acgagaaatt ccttatactc gtattattga gcataaacac tttgagtatg gtactcagga
    79261 gaaaacggtt attactcgtg aatacccagc tgatttcttt ttgcataata gaaaacatta
    79321 taagaggaac tctaaatgac aaggattagt atgaaaaaaa taaaagaata cgaaatttta
    79381 aaagtaatag ccattatctt agttgtggta ggacacagca cctactataa tatttatact
    79441 ggttatggtg ggatagatta tcaacaatac ataaacaacc atttatcctt agctgtatat
    79501 aagctgttaa gtaaattgac agagattatt tattattttc atatgccttt attcatggct
    79561 atatctggtg cgtttttctc tattcaggtt aaaaataatc gatggcatgg cattggctca
    79621 ttattaacaa ataagtttag aagactaatg ataccatttt tagtctttac tctagtatat
    79681 acaataccaa taaaatacat atcaaattac tttgatggta tctctttctg gaaagcggtc
    79741 tctggacaat tatttctatt tggaaattct cacttgtggt atttgtatgc attgtttatt
    79801 gtctttatag ttggctttta tattctgaaa aaacgtacgt tattttatgt ttatctactg
    79861 ctatatattc tacacatctt gagttactca gttcatttaa cattagtaag tgcaccatta
    79921 caatatctct tttggttttc tatgggcttc ttatttgaat ttaagaggga gcagtataat
    79981 cattatttaa agaataataa gtggctaagc tttttattgg tgctactatt tatagcatgt
    80041 gtagccctaa aatttgtgct taaagataac catgaagttt tgaataggat aattatggat
    80101 ctagcagctg tgctaggctc acttatttgt tataatatat cgtattatct cagtgataaa
    80161 agagaattaa cagagaatag actatttaat gttattttga ttaacggatt aggaatttac
    80221 atcttttctg atactttaaa ttatttaata ttaaatatct catattctat cagtaatcga
    80281 ttcatgttta catcatttgg tattttagca ttatttttga ttagaatttt ctttacttta
    80341 tttatagggt taggtttaac actgttattt aaaaaaatat tcaaaaaaca ttcttggtta
    80401 gtaaactaac caactttagt taatttatta ttgtcttgag gaaatattca aagagaagtt
    80461 tttgaaattt ttctattact ctagaaatag atactggaag attgtggtca tgtatttctt
    80521 atctattttg taaccgccca ataacgaagt atattgaaaa atc
//
LOCUS       DAVEHY010000006        62708 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVEHY010000006 DAVEHY010000000
VERSION     DAVEHY010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.006"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..248
                     /locus_tag="VUZ44_000494"
     CDS             <1..248
                     /locus_tag="VUZ44_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HEU0319461.1"
                     /translation="NEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKS
                     YNSLFYMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            375..1334
                     /locus_tag="VUZ44_000495"
     CDS             375..1334
                     /locus_tag="VUZ44_000495"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU0319462.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQEKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            1431..2270
                     /locus_tag="VUZ44_000496"
     CDS             1431..2270
                     /locus_tag="VUZ44_000496"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU0319463.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(2318..2488)
                     /locus_tag="VUZ44_000497"
     CDS             complement(2318..2488)
                     /locus_tag="VUZ44_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU0319464.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            2609..3493
                     /gene="miaA"
                     /locus_tag="VUZ44_000498"
     CDS             2609..3493
                     /gene="miaA"
                     /locus_tag="VUZ44_000498"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU0319465.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            3486..4724
                     /gene="hflX"
                     /locus_tag="VUZ44_000499"
     CDS             3486..4724
                     /gene="hflX"
                     /locus_tag="VUZ44_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU0319466.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMKELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIAFMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESITFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            4717..5340
                     /locus_tag="VUZ44_000500"
     CDS             4717..5340
                     /locus_tag="VUZ44_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU0319467.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            5355..6284
                     /locus_tag="VUZ44_000501"
     CDS             5355..6284
                     /locus_tag="VUZ44_000501"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU0319468.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGEIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGVKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            6305..7060
                     /locus_tag="VUZ44_000502"
     CDS             6305..7060
                     /locus_tag="VUZ44_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU0319469.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(7114..8022)
                     /locus_tag="VUZ44_000503"
     CDS             complement(7114..8022)
                     /locus_tag="VUZ44_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU0319470.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            8086..8355
                     /locus_tag="VUZ44_000504"
     CDS             8086..8355
                     /locus_tag="VUZ44_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU0319471.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            8355..8735
                     /locus_tag="VUZ44_000505"
     CDS             8355..8735
                     /locus_tag="VUZ44_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU0319472.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            8824..9051
                     /locus_tag="VUZ44_000506"
     CDS             8824..9051
                     /locus_tag="VUZ44_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319473.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFLIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(9091..9816)
                     /locus_tag="VUZ44_000507"
     CDS             complement(9091..9816)
                     /locus_tag="VUZ44_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU0319474.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDCTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            9978..11819
                     /gene="typA"
                     /locus_tag="VUZ44_000508"
     CDS             9978..11819
                     /gene="typA"
                     /locus_tag="VUZ44_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU0319475.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            11839..12093
                     /locus_tag="VUZ44_000509"
     CDS             11839..12093
                     /locus_tag="VUZ44_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU0319476.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            12457..12756
                     /locus_tag="VUZ44_000510"
                     /pseudo
     CDS             12457..12756
                     /locus_tag="VUZ44_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            12827..14848
                     /locus_tag="VUZ44_000511"
     CDS             12827..14848
                     /locus_tag="VUZ44_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU0319477.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNSGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRNLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            14850..15491
                     /locus_tag="VUZ44_000512"
     CDS             14850..15491
                     /locus_tag="VUZ44_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319478.1"
                     /translation="MIELKNISKKFGSRQLFSDMNLHFEGGKIYALIGTSGCGKTTLL
                     NMIERLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLIHAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            15595..16947
                     /locus_tag="VUZ44_000513"
     CDS             15595..16947
                     /locus_tag="VUZ44_000513"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU0319479.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMAAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            16949..18007
                     /locus_tag="VUZ44_000514"
     CDS             16949..18007
                     /locus_tag="VUZ44_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU0319480.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            18017..19216
                     /gene="divIB"
                     /locus_tag="VUZ44_000515"
     CDS             18017..19216
                     /gene="divIB"
                     /locus_tag="VUZ44_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU0319481.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQKDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYISVLFNDSEQIKAFT
                     SELAQINPELKVAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            19449..20150
                     /gene="pyrF"
                     /locus_tag="VUZ44_000516"
     CDS             19449..20150
                     /gene="pyrF"
                     /locus_tag="VUZ44_000516"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU0319482.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            20184..20816
                     /locus_tag="VUZ44_000517"
     CDS             20184..20816
                     /locus_tag="VUZ44_000517"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU0319483.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            20996..21400
                     /locus_tag="VUZ44_000518"
     CDS             20996..21400
                     /locus_tag="VUZ44_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319484.1"
                     /translation="MKRRKIYSLFCVVTIASSLFLPTVLARQIGDYDLTLPRWGSDTT
                     SELEKENASAGINNNDSTGGGKTLNTSIRSAYSGSDITPVYSLGSGSRIVMYYNGGGD
                     NYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            21496..22260
                     /locus_tag="VUZ44_000519"
     CDS             21496..22260
                     /locus_tag="VUZ44_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319485.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSAHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            22260..23012
                     /locus_tag="VUZ44_000520"
     CDS             22260..23012
                     /locus_tag="VUZ44_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319486.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            23022..23720
                     /locus_tag="VUZ44_000521"
     CDS             23022..23720
                     /locus_tag="VUZ44_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319487.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            23717..24364
                     /locus_tag="VUZ44_000522"
     CDS             23717..24364
                     /locus_tag="VUZ44_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319488.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(24451..25317)
                     /locus_tag="VUZ44_000523"
                     /pseudo
     CDS             complement(24451..25317)
                     /locus_tag="VUZ44_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(25329..26087)
                     /locus_tag="VUZ44_000524"
     CDS             complement(25329..26087)
                     /locus_tag="VUZ44_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU0319489.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(26088..26765)
                     /locus_tag="VUZ44_000525"
     CDS             complement(26088..26765)
                     /locus_tag="VUZ44_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU0319490.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTTEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(26725..27405)
                     /locus_tag="VUZ44_000526"
     CDS             complement(26725..27405)
                     /locus_tag="VUZ44_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU0319491.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSRK"
     gene            27620..27766
                     /locus_tag="VUZ44_000527"
     CDS             27620..27766
                     /locus_tag="VUZ44_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU0319492.1"
                     /translation="MSYKTSNAEGHVDFINTYDLETMAQQVIPKAAFGYIASGAEDTF
                     ASFQ"
     gene            27894..29384
                     /gene="lysS"
                     /locus_tag="VUZ44_000528"
     CDS             27894..29384
                     /gene="lysS"
                     /locus_tag="VUZ44_000528"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU0319493.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            30008..31144
                     /gene="lctO"
                     /locus_tag="VUZ44_000529"
     CDS             30008..31144
                     /gene="lctO"
                     /locus_tag="VUZ44_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU0319494.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKDEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      31398..31486
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            31701..32369
                     /locus_tag="VUZ44_000530"
     CDS             31701..32369
                     /locus_tag="VUZ44_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU0319495.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(32519..32611)
                     /locus_tag="VUZ44_000531"
                     /pseudo
     CDS             complement(32519..32611)
                     /locus_tag="VUZ44_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            32695..33477
                     /gene="thiM"
                     /locus_tag="VUZ44_000532"
     CDS             32695..33477
                     /gene="thiM"
                     /locus_tag="VUZ44_000532"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU0319496.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPVVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            33479..34108
                     /locus_tag="VUZ44_000533"
     CDS             33479..34108
                     /locus_tag="VUZ44_000533"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU0319497.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALRGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIMKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      34317..34405
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            34667..35227
                     /locus_tag="VUZ44_000534"
     CDS             34667..35227
                     /locus_tag="VUZ44_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU0319498.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            35228..36613
                     /locus_tag="VUZ44_000535"
     CDS             35228..36613
                     /locus_tag="VUZ44_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319499.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            36615..37265
                     /locus_tag="VUZ44_000536"
     CDS             36615..37265
                     /locus_tag="VUZ44_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU0319500.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            37276..37968
                     /gene="tenA"
                     /locus_tag="VUZ44_000537"
     CDS             37276..37968
                     /gene="tenA"
                     /locus_tag="VUZ44_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU0319501.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKVFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            37973..38497
                     /gene="thiW"
                     /locus_tag="VUZ44_000538"
     CDS             37973..38497
                     /gene="thiW"
                     /locus_tag="VUZ44_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU0319502.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            38497..39300
                     /locus_tag="VUZ44_000539"
     CDS             38497..39300
                     /locus_tag="VUZ44_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU0319503.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            39293..39925
                     /locus_tag="VUZ44_000540"
     CDS             39293..39925
                     /locus_tag="VUZ44_000540"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU0319504.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMDTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(40135..40941)
                     /gene="thiD"
                     /locus_tag="VUZ44_000541"
     CDS             complement(40135..40941)
                     /gene="thiD"
                     /locus_tag="VUZ44_000541"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU0319505.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIHPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCT
                     FAAVITAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(41025..41123)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41307..41702
                     /locus_tag="VUZ44_000542"
     CDS             41307..41702
                     /locus_tag="VUZ44_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU0319506.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            41713..42084
                     /locus_tag="VUZ44_000543"
     CDS             41713..42084
                     /locus_tag="VUZ44_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU0319507.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            42094..44337
                     /locus_tag="VUZ44_000544"
     CDS             42094..44337
                     /locus_tag="VUZ44_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU0319508.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            44544..46319
                     /gene="spxB"
                     /locus_tag="VUZ44_000545"
     CDS             44544..46319
                     /gene="spxB"
                     /locus_tag="VUZ44_000545"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU0319509.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            46430..46777
                     /locus_tag="VUZ44_000546"
     CDS             46430..46777
                     /locus_tag="VUZ44_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU0319510.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(46894..47895)
                     /locus_tag="VUZ44_000547"
                     /pseudo
     CDS             complement(46894..47895)
                     /locus_tag="VUZ44_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            48215..48496
                     /locus_tag="VUZ44_000548"
     CDS             48215..48496
                     /locus_tag="VUZ44_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU0319511.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            48628..49572
                     /gene="manA"
                     /locus_tag="VUZ44_000549"
     CDS             48628..49572
                     /gene="manA"
                     /locus_tag="VUZ44_000549"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU0319512.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(49593..50860)
                     /locus_tag="VUZ44_000550"
                     /pseudo
     CDS             complement(49593..50860)
                     /locus_tag="VUZ44_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            51161..51906
                     /locus_tag="VUZ44_000551"
                     /pseudo
     CDS             51161..51906
                     /locus_tag="VUZ44_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(51935..52390)
                     /locus_tag="VUZ44_000552"
     CDS             complement(51935..52390)
                     /locus_tag="VUZ44_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU0319513.1"
                     /translation="MNRREAVEFVNMCMIKNGDKILVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(52410..53585)
                     /locus_tag="VUZ44_000553"
     CDS             complement(52410..53585)
                     /locus_tag="VUZ44_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU0319514.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSLVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(53644..54489)
                     /locus_tag="VUZ44_000554"
     CDS             complement(53644..54489)
                     /locus_tag="VUZ44_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU0319515.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            54614..55171
                     /locus_tag="VUZ44_000555"
     CDS             54614..55171
                     /locus_tag="VUZ44_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU0319516.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            55190..55657
                     /locus_tag="VUZ44_000556"
     CDS             55190..55657
                     /locus_tag="VUZ44_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU0319517.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            55746..56375
                     /gene="upp"
                     /locus_tag="VUZ44_000557"
     CDS             55746..56375
                     /gene="upp"
                     /locus_tag="VUZ44_000557"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU0319518.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLNLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            56549..57139
                     /gene="clpP"
                     /locus_tag="VUZ44_000558"
     CDS             56549..57139
                     /gene="clpP"
                     /locus_tag="VUZ44_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU0319519.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            57218..57466
                     /locus_tag="VUZ44_000559"
     CDS             57218..57466
                     /locus_tag="VUZ44_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU0319520.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            57568..58728
                     /locus_tag="VUZ44_000560"
     CDS             57568..58728
                     /locus_tag="VUZ44_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU0319521.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            58996..59865
                     /locus_tag="VUZ44_000561"
     CDS             58996..59865
                     /locus_tag="VUZ44_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU0319522.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            59869..60825
                     /locus_tag="VUZ44_000562"
     CDS             59869..60825
                     /locus_tag="VUZ44_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU0319523.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            60825..61589
                     /locus_tag="VUZ44_000563"
     CDS             60825..61589
                     /locus_tag="VUZ44_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319524.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKVKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            61589..62299
                     /locus_tag="VUZ44_000564"
     CDS             61589..62299
                     /locus_tag="VUZ44_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319525.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
BASE COUNT        18739 a        11635 c        13667 g        18667 t
ORIGIN      
        1 tcaatgaatg ggttgatggt ggacgttatt atgttggcgc tgacggagtt tggaaggaag
       61 gtcaagcaag tacagcttct tctagtaatg atagcaatag tgaatattct gctgctttag
      121 gaaaggcaaa aagttataat tcgttattct acatgtcaaa aaaacgtatg tatagacaat
      181 taacttctga ttttgataaa ttttcaaatg atgcagctca atatgccatt gatcatttag
      241 atgattaaca gatactggta ggcgaaaaaa ttccttataa ttcatttacg caaacctttg
      301 cataagtgaa tgaattttga tatactagta ctgtaagcat tttcaattac tacacaatga
      361 aaaaggagaa tatgatgagt caaaagatta ttgggattga ccttggtgga acttctatca
      421 aatttgcaat cttgacaaca gcaggagaaa tccaagaaaa atggtctatc aagactaata
      481 ttttggatga gggaagtcat atcgtagatg atatgattga gtctattcaa caccgtttgg
      541 acttgcttgg attggcagca gcagacttcc aaggtattgg aatgggatca ccaggtgttg
      601 ttgaccgtga aaaagggact gttatcggtg cctacaactt gaactggaaa acccttcaac
      661 caatcaaaca aaagattgaa aaagctttgg gtattccatt tttcatcgat aatgatgcca
      721 acgtagcagc tcttggtgag cgctggatgg gtgctggaga taaccaacca gacgttgtct
      781 ttatgacact cggtactggt gttggtggcg gtatcgtcgc agaaggcaaa ttgcttcacg
      841 gtgttgctgg tgcagcaggt gagcttggtc acatcactgt tgactttgac cagccaatct
      901 catgtacttg tggtaaaaaa ggctgccttg agacagttgc ttcagcaaca gggattgtca
      961 acttgactcg tcgctatgcc gatgaatacg aaggcgatgc agccttgaaa cgcttgattg
     1021 ataacggaga agaagtaact gctaagactg tctttgatct cgcaaaagaa ggagacgacc
     1081 ttgctttgat tgtttaccgt aacttctcac gttacttggg aatcgcttgt gctaacattg
     1141 gttcaatcct aaacccatca acaatcgtca tcggtggtgg tgtgtcagct gcgggagaat
     1201 tccttctaca aggtgttcaa aaagtttacg atgaaaatag tttcccacaa gtacgcacat
     1261 ctactaaatt agctcttgca actctaggaa atgacgctgg agttatcgga gcagcatcac
     1321 ttgtattgca ataagataat gagagaggaa aatgctaacc tagagttagt aatgttcctc
     1381 ttttattttt tatgctatac tagttaggac aatgaatgag gtgagagtaa atgacaaaag
     1441 cagatacgat ttttaaagag aatattgaac gcattctaaa ggaaggtgtt ttctcagagc
     1501 aggctcgtcc taagtacaag gatgggactg ttgctaattc caagtatgta actggtgcct
     1561 tttccgagta cgacttatct aaaggagaat ttcctatcac aaccttgcgt cccattgcaa
     1621 tcaaatccgc catcaaagaa gttctctgga tttaccaaga ccagtcaaat agcttagaag
     1681 tgcttaatga caagtacaat gttcactact ggaatgactg ggaagttgga gacacgggaa
     1741 ccattggtga gcgctatggt gccgttgtta agaaacacga cattatcaat aagcttctca
     1801 aacagttgga aaccaatcct tggaaccgcc gcaatattat ttcgctctgg gattaccaag
     1861 ctttcgaaga aacagatggg ctgctcccgt gcgcctttca gaccatgttt gatgtccggc
     1921 gtgttgatgg ggaaatctat ctggatgcga ccttgaccca gcgctccaat gatatgctgg
     1981 tggcccacca catcaacgct atgcagtatg tggctttgca gatgatgatt gccaaacatt
     2041 ttggctggaa ggttgggaag ttcttctact tcatcaacaa cctccatatc tatgataatc
     2101 aatttgaaca agctcaggaa ttgctccgtc gggagccgtc aaactgccaa ccacgcttgg
     2161 ttttaaatgt tcctgatggg actaatttct ttgatatcaa agcagaagat tttgagttgg
     2221 tggattatga ccctgttaag ccacagttga agtttgacct agctatttaa aagaatagaa
     2281 aaaagaagtt gagaataatc ccaacttctt ttgtttctta acgtgatacg cggcgacgag
     2341 ctgctttttt acggttttct tcgatgaaag ctgctttttg ctcttctggt tcgattactt
     2401 tctttttaaa tgcgtatact gcacctgcaa cggcagcgac agttcctgcg acacctgtta
     2461 caagaccttt agcgaatcct ttagccatga gtcttcctcc tttatattct caatcagcca
     2521 gcctcctcaa gaggtcacat ttttctgact gacctttttg tgttataata atagtaacga
     2581 aaaaatggga atttttcaag gaaaaaagat gaaaacaaaa ataattgtga ttgttggacc
     2641 gactgctgtt ggaaagacgg ctctagctat tgaagttgca aagcgtttta atggcgaagt
     2701 ggttagtgga gatagccagc aagtctatcg aggacttgat attgggacgg ccaaggctag
     2761 tccagaagag caggcagctg ttcctcatca tttaatcgat gttagagaga taaccgagtc
     2821 ttactcggct tttgattttg tttcagaagc taagatgact attgagggta ttcacaaccg
     2881 tggcaagcta gccattatcg ccggtgggac tggactttat atccagagct tgctagaagg
     2941 ttaccaccta ggtggggaga ctcctcatga ggagatttta gcttatcgag ctagtttgga
     3001 gccatattca gatgaggaat tagcccattt ggtggatcaa gcaggccttg agattcccca
     3061 gtttaatcgt cgtcgtgcta tgcgtgcctt agaaattgcc cattttggtc aggatttgga
     3121 aaatcaagag accttgtatg aaccgctgat tatctgcttg gatgatgaac gtagtcaact
     3181 ttatgagcgt atcaaccacc gagtggattt gatgtttgag gctgggcttt tggatgaggc
     3241 caagtggctg tttgaccatt cccctaatgt acaggctgct aaaggaattg gctataagga
     3301 actctttcct tatttccgtg gagagcagac cttggaggaa gctagtgaga gtctcaaaca
     3361 ggcgacccgt cgttttgcca agcgtcagct gacctggttc cgtaatcgca tgcaggtcac
     3421 cttttatcag attggagaat ctggtgtaca agaccgcatt ttaagccaga tagaggagtt
     3481 tttagatgat tgaaacggag aaaaaagagg agcgagtcct gctgattggt gtggaattgc
     3541 agggtatgga cagttttgac ctctccatga aagaattggc tagtttagcg aaaacggcag
     3601 gggcagtcgt tgtagatagc tacagacaaa aacgtgaaaa atatgattcc aagaccttcg
     3661 tcggctctgg taagttggaa gagattgcgt ttatggtgga tgcagaagaa atcactactg
     3721 tcatcgtcaa caaccgtctg accccaaggc agaatgtcaa tctagaggaa gttctcggtg
     3781 ttaaggtcat tgaccgtatg cagttgattt tggatatctt tgccatgcgg gctcgaagcc
     3841 atgaagggaa gctccaagtc cacctagccc aactcaaata cctcttgcct cgcttggttg
     3901 gtcaggggat tatgctcagc cgtcaggcag ggggaattgg ttcccgtggt cctggtgaaa
     3961 gccaactgga gctgaaccgt cgtagcgttc gcaatcaaat cacggatatc gagcgccagc
     4021 tcaaggtggt tgagaaaaat cgtgcgactg tcagagaaaa acgtttggag tctatcactt
     4081 ttaagattgg tttgattggt tataccaatg ctgggaaatc aactatcatg aacatcttga
     4141 ccagtaagac ccagtatgaa gcagatgagc tctttgcgac tctggatgcg acaaccaaga
     4201 gtattcatct gggaggcaac ctccaagtaa ctttgacaga taccgttggc tttatccaag
     4261 atttgccgac agagttggtg tccagtttca agtcaacctt ggaagaaagc aagcatgtgg
     4321 accttctggt tcatgttatc gatgctagca atccttacca cgaggaacat gaaaaaacgg
     4381 ttctctccat catgaaagac ctggacatgg aagatattcc tcacttgacg ctttataata
     4441 aagcggattt ggtggaggat ttcacgccta cccaaacgcc atataccctc atttctgcca
     4501 agtctgagga cagtcgtgaa aacttgcaag cattattgct agataagatt aaggaaattt
     4561 ttgaagcatt taccctgcga gtgccttttt caaagtccta caagattcat gatttagaga
     4621 gtgttgcaat tctggaagaa cgtgattatc aggaagacgg cgaagtgatt acaggctaca
     4681 tttccgagaa aaataaatgg aggttagaag aattttatga ctgatattaa aactttggct
     4741 ctaaagtatg gaggttatac aagtctggac aaggtctatc tggatcagct tctagctggt
     4801 aagacagagc aggagcagtt aacacttatt acacctccgc caagtgttgt taatgcctac
     4861 tttgcagaac tctatcagaa aaaaagtcct caggctgcga cggattattt tgcagaactc
     4921 agtcaggaac tgaatcttta caatactgag ccaagtttca ccctagaaaa taagtctttt
     4981 attcggctta atctgtctgg taaatccttt ggtttttgtt atgagagtga cggctttggt
     5041 cggattttct ctgaaaatga ggagaaaatc tcggatgact tgctctttga aattgcgcaa
     5101 attttccccc atcaactagt ctttgaagag tctggtaaga tttacatgaa gcctgtcgag
     5161 gacgaggaag ttgtcagcct agaaagtctc acagctttga ctgatttgga aagattggct
     5221 gatggtcgaa aacgtctcaa aggctacagc caagaggatt tattgcaaga agctgctgct
     5281 ttttctggca aacgctattt ccgatcggaa aaccgcacag ccatgttata tattgattaa
     5341 ttagaaagta tcgaatggat attcaatttt taggaacggg ggctggtcag ccctctaaag
     5401 ctcgcaacgt ttcaagtctc gccctgaaac ttttggacga gattaacgaa gtttggctct
     5461 ttgactgtgg agaaggtacg caaaatcgca ttctggaaac cacaattcga ccacgtaagg
     5521 tcagcaaaat ctttattacc catctgcatg gagaccacat ttttggtttg ccaggtttcc
     5581 tttctagccg tgcctttcag gccaatgaag agcagacaga tttggaaatc tacggacctc
     5641 aaggaatcaa gtcatttgtc ttaaccagcc ttcgtgtgtc aggttctcgt ctgccctacc
     5701 gcattcattt ccatgagttt gaccaagatt ctttgggtaa aattcttgaa accgataaat
     5761 tcactgtgta tgcagaggag ctggaccaca ctattttctg tgttggctat cgtgtcatgc
     5821 aaaaggatct agaagggacg ctggatgctg aaaaacttaa ggctgctggt gttccgttcg
     5881 gcccgctttt tggtgaaatc aaaaacggcc aggatcttgt tttggaagac ggaactgaaa
     5941 tcaaggcagc agactatatc tcagcgccac gtccaggtaa gattatcact attttaggag
     6001 atactcgaaa aacggatgcc agtgtgcgtc tggctgtcaa tgcagatgtc ctagttcatg
     6061 agtccactta tggcaagggt gatgaaaaaa ttgctcgtaa ccatggtcac tcaactaata
     6121 tgcaagctgc acaagtagcg gtagaagcag gtgtcaaacg cctcctactc aaccatatca
     6181 gtgcccgttt cctctcaaaa gatattagca aactcaagaa agacgctgcc acaatttttg
     6241 aaaatgtcca tgtggtcaaa gacttggaag aagtggaaat ctagcagtca cagaaaggat
     6301 aagtatgcct actattctca ttaccggagc tagcggtggt ctagctcaag aaatggtcaa
     6361 actcctgccc aatgaccaac tcatcttgct tggtagaaat aaggaaaaat tagcccaact
     6421 ctacggaaat tattcccatg cagaattgat tgaaattgat attaccgacg attcagccct
     6481 agaagctctg gtaactgatc tttatctccg ctatggcaag attgatgtct tgattaacaa
     6541 cgctggttac gggatttttg agggatttga ccaaattgct gataaagaca ttcaccagat
     6601 gtttgaggtc aatacctttg ccctgatgaa tctgtctcgt caccttgcgg ctcgtatgaa
     6661 ggaaagcagc aaagggcata tcatcaacat cgtcagcatg gcaggtctaa tagctactgg
     6721 caagtctagt ctttactcag cgaccaagtt tgcggctatt ggtttttcaa atgctctgcg
     6781 actcgaactt atgccctatg gagtctatgt gacaacagtc aatccaggtc caatccgaac
     6841 aggatttttt gaccaagctg acccagatgg aacttatctt aaatcggttg accgcttcct
     6901 cttagaggca gatgcagtgg ctaaaaagat tgtcaagatt ataggaaaaa ataaacgaga
     6961 actcaatctc ccgattttgt tgaacctagc ccataagttt tatactctct ttcccaagct
     7021 agctgataag ttggcagggg aaacttttaa ttataagtaa aaagaaccaa tgtgcaggtt
     7081 gttgctagcc tacatattgg ttcttatcat ttctcaacta tcaaactgaa cttcttctag
     7141 tagatagtcg ataaagcgtt cgcccatctt agataggctg gttttctcat gctggatata
     7201 gaccagctca atcgggtcat caatatccag tgggatagaa acgatattgt ctccgtttag
     7261 gttgctgttc aaaatccctg tcgcaatggt ataaccatcc aaaccaatca agagattaaa
     7321 gagggtggca cggtcactga ccacaatgga tttcttgtgg tgttcttgag aaagaatctc
     7381 ttctgaaaag tagaaggagt tgtgcgtccc ttggtcatag ctgaggtaag ggaaattctc
     7441 caaatcagac agtttcacct tgtctttctt tgccagaggg ttggtcttgc tgacaaagat
     7501 atgcggttgc gctgtgaaga gatggtgggc tagcaggtga ttgtcatcca gcatcttggt
     7561 taaaacatca cggttgtaac tgtttaagaa gaggaccccg acctcactgc ggaagttctt
     7621 gacgtcgtcg ataatctccc aagtccgagt ttcacgaagg aagagttcgt atttctccat
     7681 atcgcttttc ttgagcaaag agacaaaggc attgaccaca aaggcatagt gttgagacga
     7741 aacgctaaag agttcgcggt gggcgacagg atttttatag cgttcctcca gaagctgggt
     7801 ctgctcgaca acctgacggg cataagagag aaactccatc ccatcacggg tcaaggtgat
     7861 tcccttggga ttgcggataa agatctcaat gcccatttca ttttccaaat ctcgcactgc
     7921 attggagaga cttggctgag tgataaagag ttgcttggct gcctcattca tggagccagt
     7981 ttcgacgatt ttgataatat aatgtaattg ttgaattctc atgtttttat tgtaccatac
     8041 ttgccttaga atcgctaaag aagataggaa aataaggagc attgtgtgag tctcttcttg
     8101 aaaaaaacac aaaattttgc tagaatgagt cttatgaaaa cattctatga tgtgcagcaa
     8161 ttcctcaaac gatttggtat tattgtttac atgggaaaac gcttatatga tattgaactg
     8221 atgaagttgg aactatctcg gatttacgat gcagggttga tggataaatt agactatcta
     8281 gaggcagaag cagttcttcg cagagagcac aaggtagaat tggattatat tgagaaaaat
     8341 ggagaaaaga actaatggtt acttggattt tgtgggcact tatactagca atgttggcgt
     8401 ggatgggctt taactatctt cgtattcgcc gtgcggctaa aattgtggac aatgaggagt
     8461 ttgaagcctt gattcgtacg ggtcaattga ttgatttgcg cgacccagca gaattccaca
     8521 gaaaacatat ccttcgtgca cgcaatattc cttcaagtca gttgaaaact agtcttgcag
     8581 cccttcgtaa agataaacct gtccttctct acgaaaacca acgtgcgcaa cgagttacaa
     8641 atgcagctct ttacttgaaa aaacaaggtt tttctgagat ttatatcctt tcttatggct
     8701 tggattcttg gaaagggaaa gtgaagacta gctaacctta tttccaaatt agtcgaatga
     8761 taggatgaag ctattgtttt atagtataat taatttgtat aaaatttaaa gagttcttag
     8821 aacatgaaag aaaagaagaa aaatccactt tttgtgggta tcttgtcgat tattcttggt
     8881 ttgttatttc taattgtagg cctgattttg ggtatcatag gattggtctt ggctatttca
     8941 taccaaaaag agtcacaatt agactataaa atagaaaaga ttcttaatat cttaggaatt
     9001 gtgatttctg tagttaactg gattgtagca atcgccttaa tttttcggta aataaaagaa
     9061 aaaagcttta gttttaaagc tttttttatt ttatcgactc atctctaaat agtttttaat
     9121 gatttgtaac tctttttggt tcaaagggcg gtagttacct tctgctaaat ctgggttcaa
     9181 tgtgaagtcc ccaaattgga ttctcttgag gatagtcacc ttaacaccaa ccgagaggaa
     9241 cattttcttg atttgatgaa attttccttc tgaaatggtg atagaggctt gactgatgga
     9301 gggacttgca gatagaatct ctagttttgc gggtttacag acagtacaat ctaaaaagac
     9361 aattcccttt tgaaaggctt ggatatggtc aggtgttaga agtccattaa cctcaacttg
     9421 ataagtctta tcgacatgat attggggatg gaggagttgg aagcccaagg gaccgttatc
     9481 ggtcaagaga aggagtcctg ttgtatctcg gtccagtcgg ccgacggcat agagcttgtc
     9541 agactggatg tcagatggaa gcaagtccat gacggtcgga agttccttgt ctttgttggc
     9601 tgtaacgaca ccagcaggtt tatgaagcat aagataggtg tgttcatagc cttgaatgat
     9661 tcgatcctga aaaaggagtt cttgtagtcc tgtatcgata ttttgagcta gggagcgggc
     9721 tgggcaacca tcgactagaa tgtcccctct gaggagtgct tgcttcatgg cctttcggct
     9781 aactttttct tgggctaata aattatctaa acgcatactg tgcctatctt atcataagtc
     9841 gcttgctttg aaaaggcttg acgtgaaaag aaaagcggag tgaaaacatt tacacttgct
     9901 tgagttatgt tatttatttg aaattatggt ataatcgttc agttagaaaa taaattttga
     9961 atattataga ggaaatcatg acaaaattaa gagaagatat ccgtaacatt gcgattatcg
    10021 cccacgttga ccacggtaaa acaaccctgg ttgacgaatt attgaaacaa tcagaaacgc
    10081 ttgatgcacg tactgaattg gcagagcgtg ctatggactc aaacgatatc gaaaaagagc
    10141 gtgggattac catccttgct aaaaatactg ccgttgctta caacggaact cgtatcaaca
    10201 ttatggacac accaggacat gcggacttcg gtggagaagt tgagcgtatc atgaaaatgg
    10261 ttgacggtgt tgtcttggtc gtagatgcct atgaaggaac catgccacaa actcgtttcg
    10321 tattgaaaaa agccttggaa caagaccttg tcccaatcgt ggttgttaac aaaatcgata
    10381 agccatcagc tcgtccagca gaagtagtgg atgaagtctt ggaacttttc atcgagcttg
    10441 gtgcagatga cgaccagctt gatttcccag tggtttatgc ttcagcgatc aacggaactt
    10501 cttcattgtc agatgatcca gctgaccaag aagcgactat ggcaccaatc tttgacacga
    10561 ttatcgacca tatcccagct ccagtagata actcagatga gcctttgcag ttccaagtgt
    10621 cacttttgga ctacaatgac ttcgttggac gtatcggtat cggtcgtgtc ttccgtggta
    10681 cagttaaggt tggggaccaa gttacccttt ctaaacttga cggtacaact aaaaacttcc
    10741 gtgttacaaa actcttcggt ttctttggtt tggaacgtcg tgaaatccaa gaagccaaag
    10801 cgggtgactt gattgccgtt tcaggtatgg aagacatctt tgtcggtgaa accatcactc
    10861 cgacagatgc agtagaagct cttccaatcc tacacatcga tgagccaact cttcaaatga
    10921 ctttcttggt caacaactca ccatttgctg gtaaagaagg taaatgggta acttctcgta
    10981 aggtggaaga acgcttgcag gcagaattgc aaacagacgt ttcccttcgt gttgacccaa
    11041 ctgattcacc agataaatgg actgtttcag gacgtggaga attgcacttg tcaatcctta
    11101 tcgaaacaat gcgtcgtgag ggctatgaac ttcaagtatc tcgtccagaa gttatcgtaa
    11161 aagaaatcga cggtgttaaa tgtgaaccat ttgaacgtgt acaaatcgac actccagaag
    11221 aataccaagg gtctgttatc caaagccttt ctgaacgtaa aggtgaaatg ttggatatga
    11281 tttcaactgg taatggtcaa actcgtttgg tcttccttgt tccagcgcgt ggtttgattg
    11341 gatactcaac tgagttcttg tcaatgactc gtggttacgg tatcatgaac cataccttcg
    11401 accaatactt gccattgatt ccaggggaaa ttggtggacg tcaccgtggt gcccttgttt
    11461 ctatcgatgc tggtaaggct acaacttact caatcatgtc tatcgaagaa cgtggtacga
    11521 tctttgtcaa cccaggtact gaggtttatg aaggaatgat catcggtgaa aactctcgtg
    11581 aaaatgactt gacagttaac atcacgaagg caaaacaaat gaccaacgtt cgttcagcta
    11641 ctaaggacca aacagctgtt atcaagacgc ctcgtatctt gacacttgaa gagtctcttg
    11701 agttcttgaa cgacgatgag tacatggaag taacgcctga gtctatccgt ttgcgtaaac
    11761 aaatccttaa caaagcagag cgtgagaaag ctaacaagaa gaaaaaatca gctgaataag
    11821 agctagaaag agagaaagat ggtctattta gtcctaggaa ttttactgct cctactctat
    11881 gtatttgcga caccagaaag cattaaaggg actgtcaata tcgtcgctat ggtatgtatt
    11941 ttagtggcac tcttgatttt attggttcta tcttttctga aaatttttca attaccaaca
    12001 gaaatattcc tagcaatagc catgttgatc ctagcttact ttagtgttag agacatcaca
    12061 ctcatgccag tcaaaaaaag taaaagaaga taaaaaagag agtttcggct ctctttttgc
    12121 taggaatttt acaatagttt gaattgcttt ttagttaaca ccatctcttt tacttgtata
    12181 gtatgaatgg gaaaaacttg aataaaattc gttaatggca tctattttat atttggttag
    12241 tactggttgc atattatttc gaaataaaac tactatataa tattattcac agaggtaata
    12301 tagtaaaata tctaaaaaat tcgatttttt ccttgacaac aaataataaa aaagttattc
    12361 ttatcacata agaaagcggt ttcaataaaa gatagaggag gatttatttt gtttcattgt
    12421 tgctcaaggt gtgctttttt tgaaagaaaa aataaaatga aaacgaaaaa acatagatta
    12481 cttgctctag ctcttatttc aaattttaca ttattgggag ctgcatcagc tgctgtacaa
    12541 tatccagatg gaggagtatg gacatatgga gaaggttcag gaggtggtta ggctttttca
    12601 aattactatc atggtaaaaa atatcattat tcatccatcg tgagcagatg ggatggtcat
    12661 tctgataaag gagaagctcc tgctggaaaa acctcctatg catggatttg gactaaatgg
    12721 ggagaacaag tagcatttta ctgtgattat gactaatcgt tcattgattt aaatcgttcc
    12781 ccttgtaaga aattacaggg ggaattttgt ttacaaggag tctactatga agaaactatt
    12841 catattatta tcaacttttt ttctcagctt cttccttgct tggattattg tcttacgtgc
    12901 gccacaatat ttatatgcaa gctatgattc cgtttcttta cttcgtgtca aaaaagatac
    12961 tcaggaaccg acgcgtgagg tatttgaaca ggaattggag aattttgcaa actcagaaca
    13021 gagtttaata gctagaagaa ttgtagagcc gagtaaggat gggacgactc actttactta
    13081 tgcaacttat ggtcagggaa ctttaccaaa agaattccaa gaagctagcc aagaaagtcg
    13141 tgaacgtagt gatccgctaa atagttatct ccttttgtca ggctccttga cgaaagaaaa
    13201 gcttgccgat aaattaggag atttgggtta taaagcaagt gctgaccgaa agataccgcc
    13261 ctattttctt gcttttcgaa tattactaaa tccccttatt ttaattagtt tagcaatatt
    13321 tggtttatct ttctttgctt tagtgattat cactcggatt aaggaaatga gagcagcagg
    13381 tataaaactc ttttctggtc agactctctt atccatcatg gggcattctt tatctactga
    13441 tatcaaatgg ctccttctat cagccctcct ttccttccta ggtgggggag tcgttctttt
    13501 tagtcaaggt ttgttttatc ctatcttgtt agccacctat ggttttggga ttagtttcta
    13561 tctgttgttt ttattggcga tttcaatttt actaatgctt ctttatctaa tgagtttgaa
    13621 ttacaaagca ttagttcccg ttattaaggg gagattaccc cttaaacgcc tgatgatttt
    13681 aaccctattg tgtcagttgg ttgctgtctt tacagtagga tacgctgtta agacaggttt
    13741 gacgtcttac caacgattga aagaacttga aatttcaaaa caagcatggc aggatagagc
    13801 agactattat caaatttctt ttggcttagg tgatagagga aaagatacag aaaatcagag
    13861 caagtggtat gcctttgcca aggaagcaat cgaagaagaa caagctcttt atgtaaagga
    13921 taatctgctc cattttgcca atccacaagg aaaaaatgaa cagggagaga cactggatac
    13981 ctatagtcca gatgctaata cgctctatgt tagtcccagt tatttggaca aggaaaaggt
    14041 cgtggtagat gctgagacca aacagaagtt agcccatctc caaaaaggtg agtttatcct
    14101 cttgctccca gaacatttgc gctctcgaga agcagaactt aagaaagttt ttgaagaaag
    14161 attgagttat tatggaaaat ctggtgagga ggcaagtgct cctttggatt atgagatgaa
    14221 agcgcacgtt agttatcttt caatgggaga aaagcggttt gtttataata gcggtgagaa
    14281 tcccgtatct actcagtatt tgactgatcc gattttagtg gtattcacgc cgacttctac
    14341 aggtgatagt tttatatcct tatctagttg gtctatcaat gctggaaaac aactctttat
    14401 caaaggatat gagagtgggc tagaactctt gaagaaagct ggaatttatg agcaagtatc
    14461 ctatcttaaa gaaggaagaa gtgtttatct aactcgttat aatgaagttc aaactgaaac
    14521 agcaacttta atcttaggag ctattgttgg aatagccagt tccttgttac tcttttattc
    14581 tgtcaatctt ctatatttcg agcaattccg ccgagatatc ttgattaaac gaatttcagg
    14641 tttacgattt tttgaaacac atgctcagta tatggttagc caatttgcca gttttgtatt
    14701 tggtgctagt ctctttattt taagcagtcg aaacttggtg attggcttgc tcactttatt
    14761 ggtctttcta gctagtgcag ttttgacgct ttaccgtcaa gcgcagaaag aatctcgtgt
    14821 ttctatgaca attatgaaag gaaaatagga tgattgaact aaagaatata tctaaaaaat
    14881 ttggaagccg tcagctattt tcagatatga atcttcattt tgaaggtggg aaaatttatg
    14941 ccttaatcgg tacaagtggc tgtggtaaga caacactctt gaatatgatt gaacgattag
    15001 agccatatga caaagggcaa atcatatatg atggcacttc tcttaaggac attaagcctt
    15061 ctgttttctt tagagattac ttaggatact tatttcaaga ttttggctta attgaaagcc
    15121 aaaccgtcaa agagaatctc aatctgggtt tagttggtaa aaagttgaag gaaaaagaga
    15181 aaatctcttt gatgaaacaa gctctaaacc gtgtaaacct ctcttatttg gatttgaagc
    15241 aacctatatt tgagttatca ggaggagaag cacaacgtgt tgcactagcg aagataattt
    15301 taaaggatcc acctttgatc cacgcagatg aaccaaccgc ttccttagac cccaaaaact
    15361 ctgaggaatt actttccatc ctagaatctt taaaaaatcc gaatcggacc attattattg
    15421 cgacccacaa tcctctgatt tgggagcaag tggatcaggt cattcgagtt accgatttat
    15481 cacatagatg atatggtaag attcagttag aagaaagagt cacaaacaca ctttgtggct
    15541 tttttatttc cataaaaatg gtaaaatagt aggagtagaa atggagttcg agacatgaaa
    15601 gtaatagatc aatttaaaaa taagaaagtt cttgttttag gtttggccaa gtctggtgaa
    15661 tctgcagctc gtttgttgga taagctaggc gccatagtga cagtaaatga cgggaaacca
    15721 ttcgaggaca atccagctgc gcaaagtttg ctggaagaag ggatcaaggt cattacaggt
    15781 ggccatcctt tggaactctt ggatgaagag tttgccctta tggtgaaaaa tccaggtatc
    15841 ccctacaaca atcccatgat tgaaaaggct ttggccaagg gaattccagt cttgactgag
    15901 gtggaattgg cttatttgat ttcagaagca ccgattattg gtatcacagg atcgaacggt
    15961 aagacaacca caacgactat gattggggaa gttttgactg ctgctggcca acatggtctt
    16021 ttatcaggga atatcggcta tccagctagt caggttgctc aaatagcatc agataaggac
    16081 acgcttgtta tggaactttc ttctttccaa ctcatgggtg ttcaagaatt ccatccagag
    16141 attgcggtta ttaccaacct catgccaact catatcgact accatgggtc attttcggaa
    16201 tatgtagcag ccaagtggaa tatccagaac aagatggcag cagctgattt ccttgtcttg
    16261 aactttaatc aagacttggc aaaagacttg acttccaaga cagaagccac tgttgtacca
    16321 ttttcaacac ttgaaaaggt tgatggagct tatctggaag atggtcaact ctacttccgt
    16381 ggtgaagtag tcatggcagc gaatgaaatc ggtgttccag gtagccacaa tgtggaaaat
    16441 gcccttgcga ctattgctgt agccaagctt cgtggtgtgg acaatcaaac catcaaggaa
    16501 actctttcag ccttcggtgg tgtcaaacac cgtctccagt ttgtggatga catcaagggt
    16561 gttaaattct ataacgacag taaatcaact aatatcttgg ctactcaaaa agccttgtca
    16621 ggatttgaca acagcaaggt cgtcttgatt gcaggtggtt tggaccgtgg caatgagttt
    16681 gacgaattgg tgccagatat tactggactc aagaagatgg tcatcctggg tcaatctgca
    16741 gaacgtgtca aacgggcagc agacaaggct ggtgtcgctt atgtggaggc gacagatatt
    16801 gcagatgcga cccgcaaggc ctatgagctt gcgactcaag gagatgtggt tcttcttagt
    16861 cctgccaatg ctagctggga tatgtatgct aactttgaag tacgtggcga cctctttatc
    16921 gacacagtag cggagttaaa agaataatat gaaaaaaatt gtctttacag gtggggggac
    16981 ggttggacac gttaccctca atcttttgtt aatgcccaag ttcatcgaag atggttggga
    17041 agtccactat atcggggaca agcgtggtat cgaacaccaa gaaatcctta agtcaggttt
    17101 ggatgtcact ttccactcca ttgcgactgg gaaattgcgt cgctatttct cttggcaaaa
    17161 tatgctggac gtcttcaaag ttggctgggg aatcgtccaa tcgctcttta tcatgttgcg
    17221 acttcgtcca cagacccttt tttcaaaggg gggctttgtc tcagtaccgc ctgttatcgc
    17281 tgcgcgtgtg tcaggagtgc ctgtctttat tcacgaatct gacctgtcta tgggcttggc
    17341 caataaaatc gcctataaat ttgcgactaa gatgtattca acctttgagc aagcttcgag
    17401 tttgtctaag gttgagcatg tgggagcagt gaccaaggtt tcagatcaaa aaaatccaga
    17461 accagatgaa ttggtggata ttcaaagcca ctttaatcat aaattgccga ctgtattgtt
    17521 tgttggcggt tctgcaggtg ctcgtgtctt taaccaattg gtgacagacc ataaaaaaga
    17581 actaacagag cgctacaata ttatcaatct aactggagat tctagcctga atgagttgag
    17641 ccaaaatctt tttcgtgttg actatgtgac cgatctctat caacccttga tggaattggc
    17701 tgatattgtt gtgacacgag gtggtgccaa tacgattttt gagctcttgg cgatagcaaa
    17761 attgcatgtc attgtgccgc ttggtcgtga agctagtcgt ggtgaccaga ttgaaaatgc
    17821 agcttacttt gtaaaaaaag gctatgcaga agaccttcaa gaaagcgatt tgaccttgga
    17881 tagtttggaa gagaagcttt ctcacttact aagtcacaag gaagattacc aagctaagat
    17941 gaaagcttct aaggaattga aatctctagc agatttttat caattgttga aaaaagattt
    18001 atcataagga aagtaaatgt caaaagataa gaaaaatgag gacaaagaaa ccctcgaaga
    18061 attgaaagag ttatcagaat ggcagaaacg aaaccaagaa tatctaaaaa agaaggctga
    18121 agaagaggcg gctctagctg aggagaagga aaaggaaaga caagctcgaa tgggagaaga
    18181 atctgagaag tcagaggata aacaggacca ggagagtgaa acagaccaga aagattcaga
    18241 atcagctaag gaagagtctg aagaaaaagt agcatcctca gaggctgaca aagagaaaga
    18301 agagaaagaa gaaccagagt ctaaagagaa ggaggaacag gataaaaagc tttctaaaaa
    18361 ggctacaaag gaaaaaccag ccaaagcaaa gattcctggt atccatatct tgcgagcctt
    18421 cacgatttta tttccaagtc tgcttttatt gattgtctct gcctacttgc tcagtcctta
    18481 tgcgaccatg aaagatattc gtgttgaggg aacggtgcaa actacagctg atgatattcg
    18541 acaggcttca ggcattcagg attcggatta tacgattaac cttctgctag acaaggcaaa
    18601 atatgaaaag cagattaagt ctaactattg ggttgaatca gctcaacttg tctatcaatt
    18661 tccaactaag ttcactatta aggtcaagga atatgatatt gtggcctact atatttctgg
    18721 tgaaaatcat tatcctattc tttccagtgg tcagcttgag actagttctg tgagtctgaa
    18781 cagtttacca gaaacttata tatcagttct ctttaatgac agcgaacaaa tcaaagcctt
    18841 tacgtcagaa cttgctcaaa ttaacccaga actcaaggtg gctatccaaa aggtggaatt
    18901 agccccaagc aaggtgactt ccgatttaat tcgattgact atgaatgatt cggacgaagt
    18961 cttggttccg ctttctgaaa tgagcaagaa actgccttat tatagtaaga ttaagccaca
    19021 attgtcagaa ccgagtgtga ttgacatgga agctggaatt tacagttaca ctgtggcgga
    19081 taaattaatt atggaagctg aggaaaaagc caaacaagag gctaaggaag ctgagaaaaa
    19141 acaagaagaa gaacagaaaa aacaagagga agagagcaat cgaaaccaaa cgacccagcg
    19201 ctcatcgcgt cgctaggttt accttttctc ttatagttct ttagtgacca tgtttttact
    19261 tgacaagtgc tagtagaaat aatagaataa tagaaaacct ttaaagcagt ccagagaggc
    19321 agctaaggtt agacggtgaa agggtggaga ctacccattt ttcgtggaac cttgctgttg
    19381 gcaggttcct tttttcgtgg cttctgttgg ccagactctc tcactagtaa aggtaaaagg
    19441 agaaacctat gcgagaacat cgtccaatca ttgctcttga ttttcctagt tttgaggcgg
    19501 tcaaggaatt tttagctctt ttcccagcag aagaaagcct ttatctcaag gtagggatgg
    19561 agctttatta cgcagcgggg cctgagattg tgtcctactt aaaaggtttg ggtcatagtg
    19621 tctttttgga tctcaaactt catgacattc ctaatacagt caagtcagcc atgaaggtct
    19681 tgtctcagct tggtgtcgat atgaccaatg ttcatgcggc tggtggtgta gagatgatga
    19741 aggctgcgcg tgaaggtctt ggaagtcaag caaaattgat cgctgtaacg cagctgacat
    19801 caacatcaga agcccagatg caggagtttc aaaatatcca aacaagccta caagagtctg
    19861 tgatccacta tgccaagaag acagctgaag caggcttgga tggtgtcgtt tgctcggcac
    19921 aggaagttca acttatcaag caggccacca atccagattt tatctgtctg acaccaggga
    19981 ttcgcccaca gggagctgct gttggagacc aaaaacgcgt catgacgcca gcagatgctt
    20041 atcaaattgg tagtgactat atcgtagtgg gacgtcccat tacccaagct gaggatcctg
    20101 ttgcagctta tcatgccatc aaggatgaat ggacacagga ctggaattaa agaactagat
    20161 tagaaaaata aaaggagaat accatgacac ttgctaaaga tatcgctagc cacctcttga
    20221 aaatccaagc cgtttacctc aaaccagagg aacccttcac ttgggcgtct ggtatcaagt
    20281 caccgattta cactgataat cgtgtgacac tagcctatcc agaaactcgt accctaattg
    20341 aaaatggttt tgtggaagct atcaaagaag cctttcctga agtagaagtg attgcaggaa
    20401 ctgcaacagc agggattcca cacggagcca ttattgctga taagatggac ttgccttttg
    20461 cctacatccg tagcaaacca aaagaccacg gagctggtaa tcaaatcgaa ggtcgcgtag
    20521 ctcaaggtca aaaaatggta gtggttgaag accttatttc aacgggtggt tcagttcttg
    20581 aagctgtagc agcagccaag cgagaaggag cagatgtact tggagttgta gcgattttca
    20641 gctaccaatt gccaaaagca gataagaact ttgcagatgc tggtgttaaa cttgtgacgc
    20701 tttcaaacta tagcgagctt atccatctag cccaagaaga aggttacatc acgccagagg
    20761 gccttgatct tctaaaacgc tttaaagaag accaagaaaa ttggcaagaa ggttaggtca
    20821 gtaagataaa gagagacgag gttaccgagt ctcttttacc attttattta aaatatgata
    20881 atattttaaa taaaataatt gacaacgctt tcttttattg atataatgaa aatgtaatat
    20941 gtatcaaatt gatcaatcaa ctatcttgtt tatcacttct taagaggacg atgtcatgaa
    21001 aagaagaaaa atatattccc ttttttgcgt agttacaatt gcatctagtt tgtttctccc
    21061 tacagtttta gctagacaga ttggagatta tgatttaacg ttgccacgtt ggggttcgga
    21121 tacaactagt gagcttgaga aagaaaacgc ctctgctgga attaataata atgacagtac
    21181 tggtggcggt aaaacattaa atacctctat tcgtagcgcc tatagtgggt cagatattac
    21241 tccggtatat tcattggggt ctggctctag gattgtcatg tactataatg gaggtggtga
    21301 caattatatt ggttctggta ctagattagc tatggcgcca caatttggaa atcatgtaag
    21361 aattcatact tcaggttctt ggagtccaga ttcttattaa cttacttgtc agagtaagcc
    21421 ttaaagatgg ttgattgtgg gtgtagcatg aaaaaagaat gctacaccct atttttatta
    21481 taaggaggag taaggatgga atttttcatt tgtaatcttg tacgagtcgt tcaatcacct
    21541 cgattttata tgtctttatt tttgaccctt ctttgcatga gtttaggaaa tttccttgct
    21601 ttcaatggta tttataaaat tgaaggttta tcgatttttt ttgccgcttc ttctattcga
    21661 ggattttcac cgattagcct agtagctgca cttatctgta cactgcccta ttctagtcag
    21721 ataatagagg atgctgagag tcattttcta acagcacaat tgtgccgaat ttctaaaaag
    21781 aggtatctag ctattgtagg tagtactgca attatttctt cttttctagt cttttttctc
    21841 ccctatttat tattattagg aattaatctt ttagtgactc cttatcagga aatttatatt
    21901 ggagattata gtggtgcctt aaaagaatta tttgattcca atcagttgct ctatagtctt
    21961 gtgacgactc tctggtatgg agtttggggc gctgtgttct ctatttttgg actagctagt
    22021 gctttgctag tgaagaaaaa attaggagct attttcatcc cagttgccta tatgatggtt
    22081 ggtggtattt tatgggctat tttagggcta tcttacttag aacctgtgac aacgctagct
    22141 ttgggatatc agaaagatat cagtctttcc ttagttagtg ctcatcttgc ttttatttta
    22201 tttgttagtt gtttggttgt ttatggtaca ttttttctac attcagagga ctatgtataa
    22261 tgaaacaatt tgttcaattt tataaaaaag atttcttagc agtattggtt tattttatat
    22321 tactgctatc ctgtgtttta tctagtacag tatatttatt gcgctgtcgc caatattcaa
    22381 tccatccaaa tgtattagaa tggatcttag ttttacttca agatatgacg actggagtat
    22441 attgctttcc gttcacatat atattgttct ttttttattt gatgaataac tattttaata
    22501 ggttggagtg tcgcattcgt ctgaaatcaa ttaagcactt taccagtttt agtttcaaat
    22561 tagcagctct tagtacgggg atttggacgg cgactttatt tttattgatt tttctaattg
    22621 catttagtaa tggttttagc ttctctttgg agataaagga ggttgatttt ttaagagaat
    22681 tttatggtat aagtattgca aacaatgcta gtttctttat aggatttttt ttctcttata
    22741 tagcatacta tttcttttta tccttactta ctattagcag tttttcttgg tttaaaaaat
    22801 caaacatgag cttagtattt ctgtttactt ttttatttgt agaatcctta ttctggattt
    22861 atcagttgga caatgggata attggattat tgccaatttt tcagtatatg gtaaattcca
    22921 atccgtatgc attgatttat tggcttacat tactatctat cataattcca ttgactgtat
    22981 tttctgttca tagaaactgg aggagagtgt aaaagttgga aatgggaaag ttaagtagtc
    23041 acatgtggag gttgaatcag ataatctata ccaagtactt ttggggttat gttctttttt
    23101 ggatattgat ttgtttagga ttatggtatt ggttagaagg aaatgataga cttgttatag
    23161 aaattttaaa agggcctaat ctgagtcaaa actctttttt agtcttatct atatggttgc
    23221 ttcattggtt tattattcat acattttttc tagcagttgt atatcgtaga agagcatccg
    23281 atttctttat ggaagtgatt cgattttctt ctattaagct ctggattagg tatcagattt
    23341 ggacctgttt tctttatgga ctcattttaa tcatggtaaa agttctagtg attcaattta
    23401 tgttacagtt accaaactgg gatataggag ttttgtttat agttgattct ttgaatgctt
    23461 gtgtgttagt cttgttttgc tttatgttat acgcactagg agcgaatgta caaatgaact
    23521 ttgcttgcgt tagtttcttt ttactcatga ttgtgtttgg tggtctattt gtaggaaatc
    23581 gaactaatta tctattttat attttgaatc gagggaatgg agatatagga cgagatttat
    23641 ttcttcagtt gctattttta gtctttcttt ttaaaagcat tttctatttc actcgtcaaa
    23701 agaggaggtt tatagaatga atgaaataat tacattaaaa aatattgagt tgaaattaaa
    23761 aaaaacatgt gtttttcaaa accttaattt tagctgtaaa cagggggaaa ttataggaat
    23821 tactggtgcg aatggctcag gtaaaagtgt attgtttaaa ttaatagctg gtttatatag
    23881 tccgtcttat ggagaagtgt taatcaatgg ggaaaatatt gttcctgaga gaaaaattcc
    23941 agctaatttg ggagctttga ttgaagaacc tggttttata aattattata gtggctttaa
    24001 gaatttacaa tatttggcaa gcatacgagg agtagttggt aatcaggaaa tcaatgatac
    24061 actgaaaata gttggtctat atgagcaaaa agaccaaaaa gttaaaactt attcgctagg
    24121 tatgaggaaa aagctaggga ttgctcaagc aattatggag aatccctcta ttcttttact
    24181 agatgaacct atgaatgcct tggataaatc aagtgtagaa aatatgagaa cattgtttag
    24241 aaagctctct agtgaaaaag ggacaacaat tttgattgct agtcatagtg aagaggatat
    24301 tcgtatctta tgtgataaag tatatgcaat agaagataaa gtatgtacac tgtgttcaga
    24361 ttgaacatct tagatagact caggatgtta taggtaaaat cttaaaaagg gattggagct
    24421 taaaatccag ttccttttaa gagttaatga ctaatcaact tttccacctt caacaaccag
    24481 gtcatctgct ttagcagtgt caccgtaggt tgggtgaagt gttttttcat aggccttgtg
    24541 gaagaagttt tccttgctaa tttttcaata tctttattga tgaagtctag caattcttgg
    24601 ttgccttttt gaactgctgc cgcaatggta tcgggatcac cgagggaagt aattcctact
    24661 tcaaatcctt tattttcaag cgcccaagct agaacttccg tattgtcagt tgaaaaggca
    24721 tctccacgtc cgtcaagaag agcttggtaa gagtcactgt attggtcgta tttttggagt
    24781 ttgatttctg gatgattctt ttcaaaataa gtctcagcag tcgttccttt tgtgacaatt
    24841 aaggttttac cttcaagttg tttgacgtct gtaatgagac cagtcttagg tgatacgaca
    24901 cccagagaaa ctttcatata tggaagggca aaatcaactt gtttcttacg ttcgtcagtt
    24961 actgtaaagt tagcaagagt aatatctacc ttgtttgaaa tcaagtattc cgcacggttg
    25021 gcagcatcga ctgaaatgta tttaaccttg acaccaaggt ctttagctag ttggttccct
    25081 agttcaatat cgtagccttg gtaagaacca tcattgtcaa cgtagccaaa cggtttttta
    25141 tctccaaaca cggcgattcg cagttcaccg cttttttttg atttcatcga tagtgcgagc
    25201 tttggcagtt gtttttccag aggatgaacc agcgtttcca cctgagctac aagcagtgat
    25261 aaagataagg gcaaaggcaa gtgctaaaac agttaagagt ggtttgaata gtttcataag
    25321 aatctccttt atagatatga gccaaattgg ctaaagtcaa agacgtttaa aaattcctgg
    25381 gctcgtttgg tttgcggatt ggtaaagaag gcttgagctg ttccttcttc agcgattttc
    25441 ccttggtcga ggaagataat ccggtcagca atggcttggg caaactgcat ttcgtgggtt
    25501 actaaaatca tggtacggcc ttcttgggcc aaatcattga taagttccag cacctcacgc
    25561 accatttctg gatccagcga agcagtcacc tcgtcaaaaa ggatgatttc tggatgcatt
    25621 aggagggcac ggacaattgc aacacgttgc ttctgtccac cagataattg acgggcaaag
    25681 ctatgttgtt tatccagcaa accgacacga tctagtaatt gcaaagcttc ttccgttact
    25741 tctttcttgt cccttccttg agttttgata gggcctagga tgaggttttg taagacatcc
    25801 agatggggaa agagttcata actttgaaag accatgccaa tcttttggcg aactaggtga
    25861 aaattttttt tattttcaac gatagactga ccatccagaa aaatatctcc accttgaata
    25921 ctttctaagc cgttgaggca acgaaggagg gtacttttcc cacaaccaga tggccctagg
    25981 atgacaacaa cttccccttt tttgatttct agagaaagtc cttggaggat gggattgtct
    26041 ccgaaggatt tttttagttc cttgatttct aagatagttt cagacattta gtttctccaa
    26101 tgtttttcta agtgagtgga tagtttggaa atagggtagc aaactgcgaa atataagact
    26161 agaatggttc cataaatcca aaatgaagca gttgggatgg tcaggcgatt gctatcgatg
    26221 atttgttgtc caactttggt cacttccaca accccaatca aaacaactaa tgaagtggtt
    26281 ttaatcatcc gagtgacaag attgatagcc tgcggtagca gtcttcttaa gacttgtggg
    26341 atgatgatgt ggtagtaaag ttgaacatta gtcaagccga gtgcctgtcc actttcaaac
    26401 tgatgtttag ggagagaagt gatagctcca cgtaccaagt ctcccatttc agttgttccc
    26461 cagagggtaa aaacgataat agctgaagtc tcacctgaga tattgatatt aaagtttcga
    26521 gctaagccaa agtaaacgat gaagagtagc accagctggg gcatgatacg gataaagtcc
    26581 agatacaatc gtgttaaaaa tcgtatgatt ctagaatggg aggtcatgat gattcccatg
    26641 actgttccga acatcatgga taagaggaca gacaggatgg atatctcaat cgtaacgccc
    26701 aatccctgta agattctcag gagattattt ccttgaaaga gtacttggat tcccgaatcc
    26761 tgcatggcgg agcctccttt ctatccagct aaagaccagt gagatgggta gcagcatgat
    26821 cagataagca actaccaaca tagctagcgc aatgtctgtc tcatagtaga gaccaatcaa
    26881 atccttggcg acatacatga ggtcggccaa agccactgct gagaaaacag aggtttcctt
    26941 gataaggaaa atgacattgg cactaaagga ggggagtgcc accgctgttg cttgcggaag
    27001 aaccacatag cgaaagacct gtagaggtgt cagaccaata gcgaggccaa tctcctgctg
    27061 ggtttgactg atggcttcca gcccacttcg gaaagattct gccatatagg atcctcctaa
    27121 aaagacaagc ccaagcgttg cacagacttc tgaagatagg acaatcccga ttcggggaag
    27181 accgaagtag agaaagaaga gttgaatcaa aaggggcgta ttacgtgaca attcaatgta
    27241 ggctgtcgct acttgcgcca aaacagggat tcgataatgt cggatgatac taacgattaa
    27301 accgagcaga aaggatccca aaattcccca aactgcaata tgcaaggtca gaaagaatgc
    27361 cttttgatat agtggtagat attgttcaac aatggaccaa tccaaaaata gaacctccca
    27421 tctagaaata atacagttat tgtagcactt aaaatcttct ttggataata tctatttttt
    27481 attgccgtta taaggatttt ttaccataga cataaaattt ctgaaatttc caaacaaaat
    27541 atttgaaaag ttttgaaaaa aagttaagat atttttgtaa tatacaaagt aaacgcttac
    27601 ttattaaaga ggacagttta tgtcatacaa aacaagcaat gcagaaggtc atgtagattt
    27661 catcaatacc tatgatttgg agacaatggc gcaacaagtt attcctaaag cagcatttgg
    27721 ctatatcgct agtggggcgg aagatacttt cgcttctttc cagtgatttt agcgtcaggt
    27781 tctttttagt ttttaaagat tatccgtgaa tttcttactt atttatgata aaatgggagt
    27841 atcgcaaaaa atgactcatc gtattcaatt ttgagtaaaa ctaggaggat cccatgtcta
    27901 cagaacatat ggaagaacta aatgaccagc agatcgttcg ccgtgaaaaa atggctgcgc
    27961 tccgcgaaca aggaatcgat cctttcggaa aacgttttga acgtactgca aattcacaag
    28021 aattaaaaga taaatatgcc aacctcgata aagaacaatt acacgataaa aacgaaacag
    28081 ctactatcgc aggacgcttg gtaaccaaac gtggtaaagg taaagtgggg tttgcccacc
    28141 ttcaagaccg cgaaggccag attcagatct atgttcgtaa ggatgctgtc ggtgaagaaa
    28201 actacgaaat cttcaaaaaa gcagaccttg gtgacttcct tggtgtcgaa ggtgaagtga
    28261 tgcgtacgga tatgggagaa ctctctatca aggcaaccca catcacacac ttgtctaagg
    28321 ctcttcgtcc tcttcctgag aaattccatg gtttgacaga cgttgaaaca atttaccgta
    28381 aacgttacct tgacttgatt tctaaccgtg aaagctttga acgttttgtc actcgttcaa
    28441 aaatcatctc tgaaatccgt cgttaccttg accaaaaagg attccttgaa gtggaaacac
    28501 ctgttcttca caacgaagcc ggtggtgctg ctgcccgtcc atttatcacc caccacaatg
    28561 cccaaaacat tgacatggtg cttcgtatcg cgactgagct tcacttaaaa cgccttatcg
    28621 tgggtggtat ggaacgtgtc tatgaaattg ggcgtatctt ccgtaacgaa ggaatggatg
    28681 ctactcataa ccctgagttc acttctatcg aagtttacca agcttatgca gacttccaag
    28741 atatcatgga cttgacggaa ggcattatcc aacatgctgc taaatcagtt aagggcgatg
    28801 gcccagtcaa ctatcaaggt actgaaatca agattaacga accatttaag cgtgttcata
    28861 tggtggatgc tatcagagaa attactggtg tcgatttctg gcaagacatg actttggaag
    28921 aagctaaagc tatcgctgct gagaagaaag ttccagttga gaaacactac actgaggttg
    28981 gtcacatcat caatgccttc tttgaagagt ttgttgaaga aactttaatc caaccaacct
    29041 ttgtctatgg acatccagta gctgtatctc cactcgctaa gaaaaatcct gaagaccaac
    29101 gctttactga ccgtttcgag ctctttatca tgactaagga gtacggtaat gcctttactg
    29161 agctcaacga cccaatcgac caacttagcc gttttgaagc ccaagctaaa gccaaagaac
    29221 ttggtgatga tgaagcgaca ggaatcgact atgactacat tgaagctctt gaatacggta
    29281 tgccaccaac aggtggtttg ggaatcggta tcgaccgtct ctgcatgctc ctcactgata
    29341 caacaactat ccgtgatgta ttgctcttcc caacaatgaa ataaattctt atcctctggc
    29401 tcttaccaga ggattttttt attcaaaaag agactgaatt taaggagaaa atgaagtgta
    29461 gtgtattgaa attgaaatag tacactttga tttctaagac attgttagaa attggtttaa
    29521 attccctaat caatttgtgc atgttttatt tcattttacg atagtacgct gaaacttttc
    29581 aaaaagtact agaaattgac ttggattccc caattgattt gttcagattc actataaata
    29641 aaaaattaat aagtgggata ggaagttagc gtcaactagg atagtatctt gcttaaacag
    29701 tatatatggg actgatataa gtccataggt cctattagag gatgttctgg tgtcttattc
    29761 acttgttttt tatagtatta gtagatagaa tcagcaaata aaaaagtagt tcaaatgcct
    29821 ggcagcaaaa aatctcaacg attcacttaa tatagactaa ggtttagagt ttaaggaaag
    29881 tagggctagt atattgtatg aaaaaataag atggttttta agcaaaactc ttgaaaatga
    29941 ttgaaaaaag agttattata gttgtatagt aaaaagcaaa cgcttactta atcgaggagg
    30001 acagtttatg tcatacaaaa caagcaatgc agaaggtcat gtagacttca tcaataccta
    30061 tgatttggag ccaatggcgc aacaagttat tcctaaagca gcatttggct atatcgctag
    30121 tggggcggaa gatactttca ctttaagaga gaatatccgc gcctttaacc acaaactcat
    30181 cgttcctcat acactttgcg atgttgaaaa tccaagtaca gagattgaat ttgcaggtga
    30241 aaaactatct tcgccaatca ttatggcacc tgttgcggct cataaattgg caaatgaaca
    30301 gggggaagtg gcgactgcgc gtggtgtgca tgagtttggt tctctttata caaccagttc
    30361 ttactctact gttgaccttc cagagatttc tgaagccctt caagggacac ctcattggtt
    30421 tcaattttac tttagtaagg atgacggtat caaccgccac atcatggacc gtgtgaagga
    30481 tgaaggttat aaagcgattg tcttgacggc agatgctact gtagggggga atcgtgaagt
    30541 ggataagcgt aatggttttg tcttcccagt tggcatgccg attgttgaag aatacctgcc
    30601 agaaggtgct ggtaaatcaa tggactttgt ttacaaatca gctaaacaac gcttgtctcc
    30661 acgcgatgta gaatttatcg ctgaatactc tggtcttcct gtgtatgtca agggaccaca
    30721 atgccgtgag gacgttgaac gttcgcttgc tgcaggagct tctggtatct gggtaaccaa
    30781 ccacggtggt cgtcaaatcg acggtggacc agctgccttt gactcgcttc aagaagtggc
    30841 agaagcagtt gatagacgtg tgccgattgt ctttgactct ggtgttcgtc gtggtcaaca
    30901 cgtctttaaa gccttggctt caggagcaga cttggtagct attggtcgcc cggttattta
    30961 tggcttggct ctcggtggta gtgtcggtgt gcgtcaagtc tttgaacact tgaatgcgga
    31021 attgaagaca gttatgcaat tgtctggagc tcagaccatt gaagatgtca aacactttaa
    31081 gctccgtcac aatccataca acccaacctt cccagttgac cctcgtgact taaaattgta
    31141 ttgataaaac agattgcctc cactgaatgt ggaggttttt cttcgtgtat tggaagaata
    31201 aatcgctatc gaaaaccata gtaaaatgga ataaaaacag gacaaatcaa tcaggatatt
    31261 taaatcgatt tctaacaatg ttttagaagt agaggggtac tattctagtt tcaatctact
    31321 atatataaag atatttttcg gttaaatatc ttgctaaggc tttcattttt tgctatactg
    31381 gttcagtaat taaataatag agacatttgg ggtgctttag gctgagataa tacccattga
    31441 acctgataca gttaagactg gcgaagggaa atgtgaacag ttttttcgta tggtgaaatg
    31501 aacggtctaa tcttgtaagt caactctaat tcttgattgt aattggagtt ttttgtttat
    31561 ataaactgga taggcttgtt tagttagctc tctgcaaata ctctcgatgt gttttaaaag
    31621 gatcaagtgg aattacgatt ttgcttgata tttcttggtg ttttattaat tactaacaag
    31681 taaagagagg agaagtaaat atggaaacac aagactatgc atttcagcca ggtttgactg
    31741 ttggagaatt attaaaaagc agtcagaagg attggcaggc tgcaatcaat catcgttttg
    31801 ttaaggaact ttttgcgggg acaattgaga ataaggtctt aaaggactat ctgattcaag
    31861 attatcactt ctttgatgcc ttcttatcca tgctgggtgc ctgcgtagct cacgcagata
    31921 aacttgaatc caagcttcgt tttgccaagc aactaggctt tcttgaagca gatgaagatg
    31981 gttatttcca aaaggctttt aaagagttaa aagtagcaga gaatgactat ctagaagtga
    32041 ctttgcaccc tgtaacaaaa gcctttcagg atctaatgta ttgggcagtg gcttcatcag
    32101 actatgccca tcttttggtt atgctggtca ttgcagaagg tctctattta gactggggtt
    32161 ctaaagattt ggctctacct gaagtctata ttcattcgga atggatcaat ctccacagag
    32221 gtcctttctt tgcagagtgg gttcaatttc tggttgacga actcaatcgt gtcggtaaaa
    32281 atcgagaaga tttgacagaa cttcagcaac gatggaatca agcagtcgct ttagaattag
    32341 ctttttttga tattggttac gatgtctaga gaaggctcat gatatttaca aatttgatga
    32401 ggtaagactc ttcgaaaatc tcttcaaacc acgtcagttt caccttgccg taggtatggt
    32461 tactgacttc gtcagttcta tccacaacct caaaacagtg ttttgagctg acttcgtcag
    32521 tcttatctac aggttcaaag cagtgttttg agcaatctgc ggttagcttc ctagtttgct
    32581 ctttgatttt cattgagtat aaatcattca atgtaaatga aaaaaattct taacgaaaga
    32641 tagaaataaa tcgaaatcag tagatcgtat aaagtgaaaa ggaaggattt caatatgaca
    32701 agtttaaaat tattaaaaga aaaagcacca ttggtcattt gtataaccaa tgatgtagta
    32761 aaaaatttca cagcaaatgg attagtagca ctgggcgcct caccagccat gagtgagttt
    32821 ccagcagatt tagaggattt gttaaagtat gctggtggtt tattaataaa cataggaaca
    32881 ttgacagatg aaaattggaa attataccaa gctgctctga aaattgcaga gaaatataat
    32941 gtcccagtag ttttagatcc tgtagcctgt ggagcaggag aatatagaaa aaaagtagca
    33001 gatgatttaa tcaacaatta caaactagct gcgattaggg ggaatgctgg agagattgcc
    33061 tctttagtag gaatagatgt ggcatctaaa ggagtagata gtgcgggagt agataatatt
    33121 gacgagattg ctctagcagc aaatgagaag ttcaatattc caatagtagt aacaggtgaa
    33181 gtggatgcta ttgcggtaaa tggagaagtg gtaacgattc ataatggtag tgccatgatg
    33241 ccaaaagtta ttggaactgg atgtttatta ggggcagtgg tagcaagctt tatcggacta
    33301 gaaaaaggtc aagaattgaa atcattagaa acagcaatgt tggtttacaa tatcgctgga
    33361 gaaatggcag aaaaacgtcc aaatggacat cttcctggga catttaaagt tgaatttata
    33421 aatgccttat acgagattac agatgaagat gtaaaggaat tcaaaagagt gaagtaagat
    33481 gtttcataaa gaattactaa aactatattt tatttgtgga acgactactt gccaaggaaa
    33541 aaatctatat acagtcgttg aggaagcctt aagaggtggt ataaccttat ttcaatttcg
    33601 agaaaaaggt gagggtgctt tagaaggctt agaaaaactt gagctagcta tccaaattaa
    33661 agaactttgt aaaaaataca atgtgccgtt tatcgttaat gatgatatcg atttggcaat
    33721 ggaaattgac gctgatggcg tacatgtagg tcaagatgat attggtgttg atgaaattag
    33781 aaaattgatg ccagataaaa taattggtct ttctataaaa aacgaggaag aatttcaaca
    33841 atcaaaagtt gaatatgtag attatgttgg tgttggtcct gtatttgata cccagtcaaa
    33901 ggatgatgct ggtggtgcta taggttatga aggtgttaaa ttgatgagaa aactattgcc
    33961 acaaatgccc ttagttgcaa ttggtgggat acagacgaaa catattaaag acattatgaa
    34021 gaccaatgtt gacggcgttt caatcatttc ggcaatatcg tatgcaaaaa atatagaaaa
    34081 aactgttcgg gaaatgagtg aacaatagat atctatcctt ggattctaag taagtaggat
    34141 tttccttttt taaaaagcta tgtctagatt cagcttgaat agctaattca tcaaacaggt
    34201 catttgtttt ttgcaaaaga aagatctgct gtctttgtga gtgcaaggct gtatttccag
    34261 ttcaatttct tgaactagta taaaatgtgt gttataataa tcacataatt aaataataaa
    34321 ggcatttggg gtgctttagg ctgagatgat acccattgaa cctgatacag ttaagactgg
    34381 cgaagggaaa tgtgaaatgt ttttttcgta tgtcgaaaag aactgtctaa tcttgtaagc
    34441 tgaactctaa ttcgtatctg taattagagt tttttctttt acgaaactgg atgaagatga
    34501 tatagtagat tgaaataaga tgcgaacaaa tcaattagaa aattcaaatt aatttctaga
    34561 aatattttag cattcttgtg tactgttcta aattcagtct gctatacaaa gtatttaggt
    34621 cggtcttctt gagtgcccca cttttcttta aaaaaaggag ttttttatgt tgaaaaaatg
    34681 gcagttaaaa gatgttatct tgcttgcttt cttgtctatc ttttttggtg gggttttcgt
    34741 tggttcagga tatgtgtata atattctcag tctactctta acacctcttg gtttgcaggc
    34801 ctttgccaat gaaatcctct tcggtctctg gtgtatggct gcgcccattg ctgccatctt
    34861 tgttccgaga gtcggaagtg caacgattgg agaagtgcta gctgcgcttg ctgaagtcct
    34921 ttatggtagc caatttggtc taggagctct tttgtctggc ttggttcaag gtttgggaag
    34981 tgaatttggt tttatcgtaa ctaagaatcg ctatgaaagt tggctctctc taactgctaa
    35041 tagtattggg attacgcttg ttagctttgt ctatgaatac attaagttag gttactacgc
    35101 cttttccctt ccgtttgtcc tttccttact tgtggtacgt tttatttctg tttatttctt
    35161 ctgtaccatc ttggttcgtg ccattgtcaa actctatcat cagtttgcaa ctggaggaaa
    35221 agcatagatg ggtctggaac tacgagcgat tcagtcccca atcttctctg agccgtttga
    35281 ttttactttt catgcgcaag cctttacctt gttagttggg agcagtggtt caggaaaatc
    35341 cagccttttt caagtcattg ctcaagtcag ttctcttccc tatagtggtc aagtcctgat
    35401 agatgggagc gaggtcagtc aactttctat catcgcacgt gtccagaagg ttggcattct
    35461 ctttcaaaat cccaatcatc aatttaccat ggagagcttg tttgaggagc tgattttcac
    35521 cttggagaat atcggctatc accttcagga aattgattct aaaatagcag aggttgtcca
    35581 gcaatgtcgt tgcgaggcaa tcttacaccg tcccattcat cacctatcag gtggggaaaa
    35641 gcaaaaagca gcgctggctg tcctctttgc catgaatcct agggtctatc tcttggatga
    35701 accttttgct tccattgacc gcaagagcag aatcgagata ttggagattc taaaagagtt
    35761 ggctcttgat ggaaagacag ttattttgtg cgaccatgat ttatctgact ataaagccta
    35821 tatcgaccat atggttgagc taagagacgg aaaactaagg gaagtgttcc aaatcccttc
    35881 ctatgagatg acacaggttg cttcaaagga agttgcttct agcccggaac tattccatat
    35941 ggatagaacg acttgtgagt ttggaaatcg ccccctcttt tcaattgctg atttcacatt
    36001 ctatcaaggg atttcctgta tcctgggtga caatggtgtc gggaaatcaa ccctctttcg
    36061 gtctattctt caatttcaaa agtataaggg gcgcattgca tggaagggtt cggtcctgaa
    36121 aaagaaaaag agtttgtatc gtgatctgac tggtgttgtt caggaagctg agaagcagtt
    36181 tatccgagtc agtctgcgag aggagcttca attagatgga cctgattctg aaagaaatca
    36241 gcggattttt caagctttac gatattttga tttggagcag gcagtcgata agagtcccta
    36301 tcaattaagt ggtggtcagc aaaaaattct tcagctcctg accatcttga ccagtaaggc
    36361 ttccgtgatc ttgctagatg aaccttttgc aggtttggat gatagagcct gccattattt
    36421 ttgcaagtgg attgtggagg agaggaatca aggaagaagt tttctgctca ttagtcatcg
    36481 tttagaccct ttgatttctg tggttgatta ttggattgag atgactagtc agggtcttcg
    36541 gcatgtgaaa gaagtgacca ttaccaaacc acttacatct cagagtagca atacccaagg
    36601 ggaggtgaga tagtatggtc aaagtagcaa cccagacacc gattatcagt ctcttcttgc
    36661 tgattttatc cttggaaaca tctttcattc cttcgattgc tctgaatctt tcggtagtcg
    36721 cattttgtat tctctttatg ctctattacc gtcgatttaa aatgttagct tggatgatca
    36781 tacttgccat tttaccatct tttgccaact actgggcagt tcaattacac ggagatgctt
    36841 cacaggcagt catgcttgga acgagggcct ttgtgacagt ttgtatcggc cttgtctttg
    36901 tttcctctat ttcactaaaa gagcttctct tgtacttggc tcaaaagggg ctatcacgct
    36961 cttggtccta tgccttgatt gtggtattca attcttttcc tctcattcag caagaaatca
    37021 agtccctcaa agaagcttgc ctattacgtg gtcaagaact acatttttgg tcgcccttga
    37081 tttacagtaa ggttctgatg acagtcttta ggtggcgcca tctttacctg agagctctat
    37141 ctgctcacgg atatgacgaa catgcacagt tgaagaatag ctatcggact ttttatattc
    37201 ctaaaaaaac aaaattaatc tacctgcttt tctttttatt gcttcaaacc agtctatttt
    37261 tataaaggag ttattatgga atttacagat attgcgatgg aattatccaa gaaagcttgg
    37321 caggcttcct ttcatcatcc ctttatttta caattacaag aggggaattt agaacctgcc
    37381 attttccgct attacctgat tcaggatgcc tactatctga aggttttctc agaaatctat
    37441 catcttttgg ctgataagac ttcaaaccaa gagatgaaaa gactcttgaa acaaaatgct
    37501 cagggtttag tggagggtga gttatttatt cgccaacaat ttttcaagga attggaaatc
    37561 aacgaccagg aaatggagca acatccaatc gctccaacct gttatcatta catttctcat
    37621 atttataggc aatttgcaga accgaactta gccatagctt ttgcaagctt gcttccttgt
    37681 ccttggttat accatgatat aggcaaatca cttaatctta aaccatcacc aaatcctctc
    37741 tatcaacaat ggattgaaac ttatattacg gatgagttag agcaacagat cagagaggag
    37801 ggagcattgg tcaatcagct ctatcgagaa agtgatgaga cagataagca aaaaatgcta
    37861 gatgccttcc acatcagtgt tcatatggaa gccaagtttt gggagatggc ttaccaacac
    37921 cagacatgga agagcgattt acagtcttta gaaaaaggag aagaatagaa acatgagaaa
    37981 gcaccaacta caagttcaca aattgaccat tttatctatg atgattgccc ttgatgtagt
    38041 ccttacacct atctttcgga ttgagggaat ggcaccgatg tccagtgtag tcaatattct
    38101 agcgggaatc atgatgggac ctgtttatgc cttggctatg gctacagtga cagcctttat
    38161 ccgtatgacg actcaaggga ttccgccttt agctctcaca ggagcgactt ttggagccct
    38221 tctagcaggt ctcttttata agtacggtcg aaaattttac ttttctgcct tgggagaaat
    38281 tgtgggaaca ggtattattg gttctattgt ttcctatcct gttatggtgc tctttacagg
    38341 atcggctgct aagcttagtt ggtttatcta cactcctcga tttttcggag caaccttgat
    38401 tggtacagcg atttccttta ttgcatttag atttttaatc aagcaggaat tctttaaaaa
    38461 agtgcaagga tatttctttg ctgaaaggat agaatgatgc aggcattgac aaatcctttt
    38521 cctataggct ctagttccct cattcactgt atgaccaatg agatttcttg tgagatgctg
    38581 gcaaatggga ttttggctct gggatgcaaa cctgtcatgg cagatgatcc ccgtgaagtt
    38641 cttgatttta ctaagcaaag ccaggctctc ttcatcaatt tggggcattt gtcagctgag
    38701 aaggaaaaag caatccgcat ggcagctttg tatgcaaacc aatcttctct cccgatggta
    38761 gtagatgcgg ttggcgtaac gacttcatcc attcgtaaga gcttagttaa agacctttta
    38821 gactatagac ctacggtcct taaaggaaac atgtcagaaa ttcgaagtct tgttggatta
    38881 aagcatcacg gcgttggggt cgatgcgagt gctaaagatc aagaaacgga ggatttgctt
    38941 caagtcttga aagactggtg tcagacctat cctggtatgt cattcttagt cacaggtccc
    39001 aaggacctta ttgtttcgga gaatcaagtt gctgtacttg agaatggctg tgcagaatta
    39061 gactggataa cagggacagg agatttggtt ggagccttaa cagccgtttt tctcagccaa
    39121 ggaaagactg gttttgaagc ttcttgctta gcagtctctt atctcaatat cgctgctgag
    39181 aaaatagttg ttcaaggaat gggattggaa gaatttcgtt accaagtact caatcagctt
    39241 tcgctcctaa gaagagatga aaattggcta gataccatca aaggagaggt ttatgaatag
    39301 agaagcactt agactatatc tggtaaccaa tcgctatcaa gattccgtgg aaagctttct
    39361 tgcaaaagtt gagacggcct gccgttcagg ggttaccata gtccaattgc gagaaaaaaa
    39421 tctcacaacc aatcaatatt atcaactggc aaaacaagtc aaggaaataa cagatgctta
    39481 tcaggtaccc ttgataatcg atgatcggtt ggatgtttgt cttgcggttg atgcagcagg
    39541 tctgcatatc ggagatgatg aattaccagt ttcggtagct cgcaaagtct tgggtcctga
    39601 aaaaatcctc ggtgtcaccg ctaaaacggt taaaagagct ctggaagcgg agaaatcagg
    39661 tgcagattac ttgggtacag gagccatttt cccaaccacc accaaggaaa atgcgcccat
    39721 tactctgata tcgaccttga aaacaatttg ccaaacggtt gccattccag tagttgctat
    39781 tggcggcttg acatcagaga atattgatca gcttatggac actggcatag ctggtgtagc
    39841 tgttgtacgt gatttgatgc aagcagaaga tattgaggca aaaacgcaag cctttttaac
    39901 aaagttgcat gacattcttt cctaattaat actcaatgaa aatcaaagag taaactagaa
    39961 agctagtcgc aggttgctca aagtactgcc ttgaggtttt agataagact gacgaagtca
    40021 gctcaaaaca gtgttttgaa gttgcagatg gaagctgacg tagtttgaag agattttcga
    40081 agagtataaa aactctctaa ttcccttaaa gtgggaacta gagagttttt tttcttaatc
    40141 tttaaaagtt gtatggttga ctggaccaga accatgaccg agttgagggg catcttgaat
    40201 agcttttgtg ataaaggcct tggccttatc aactgcctgg taaagactct tgcccttggc
    40261 tagttcagca gtaatcactg cagcaaaggt acatccagta ccatgggtgt gacaggtttg
    40321 aattcgtggg ctttcccaga caaattgttc attcttggta aagaggaaat ctttagcacc
    40381 acctttgaga tgtccgcctt tgagatgtcc gcctttgata accacagact gaggaccaaa
    40441 ttcttttaaa atcaggcgac cagcacgctg catgtcttcg gggtcatgga ttgaaaaacc
    40501 aacaatctct tctgcttcag gaagatttgg cgtaataata gttgctagag gtagtaagtt
    40561 tgttttgaga tagtctctag cacttgagtc aatcaaggca tctccacttg tagcaaccat
    40621 aacaggatca aggacatagg gacaatccag ttttttaaga taggggtgga tgatttccat
    40681 gatttcagta gtagccaaca ttccagtttt tacagcctga ggtggaatat cagaaaagac
    40741 actctccaat tgggctttca acatttgagg agaaacgtgc tcgattagct gaacacctct
    40801 ggtattttga gcgacaagac tggttacaac agccattcca tagacatctc tcgcttggaa
    40861 tgactttaaa tctgccataa tgccagcacc accactaggg tcagtccctg caatggtcaa
    40921 agcaacgggt aaataagtca tctaaaacct cccaaccaac tgaagtttgt attcttaaga
    40981 acaagctagt ctgttttaga aaggcaatag aagactgcta gtccccatta tcatttccac
    41041 ttccatcagc tagcattatc tagattgagt cagagggatc taacagtcgt taatctcagc
    41101 tttacgcacc cctagtggtt gttttctttt ttctttagta tagcatattt ttattgttta
    41161 tatagtaata tttgactgca aatcgttttt caaatgatta aaattctatt tttcgaagaa
    41221 aatattattt ctataattga caaatgtaga ttttaagagt atactgatga gtgtaattga
    41281 caaatgtaga ttttggaggt atggtaatgc agatttcaga tgcagaatgg caggtcatga
    41341 agattatttg gatgcagggg gagcagacca gtacagattt gattagggtt ttggcagagc
    41401 ggtttgactg gtccaagtcc acggttcaga cacttttggc tcgtctggtt gagaaagagt
    41461 gtttgactcg gaaaaaagaa ggcaagtcct ttgtttattc agccctttta actctagacc
    41521 aaagtcggga tttacttgtc caagatatca aagacaaggt ttgttcccgt aggattagga
    41581 atttgttggc tgacttgatt gtagaatgtg aatttactca gactgacttg gaagacttgg
    41641 aagctgtgat ttcagagaag aaatcaagtg ctgtaacaga agtaagatgt aattgtatgt
    41701 aaaggagacg tcatgttaaa tagtattgta accattattt gtattgccct tatcgcattt
    41761 atcttgtttt ggtttttcaa aaagcctgaa aaatctggac aaaaagccca gcaaaaaaac
    41821 ggataccaag agattcgagt ggaagtcatg ggaggctata ctcctgagtt gattgtccta
    41881 aagaaatcag tgccagcacg cattgtcttt gaccgcaagg atccttcacc atgtctggat
    41941 caaattgttt ttccagattt tggtgtacat gcgaacctgc caatggggga agagtatgta
    42001 gtggaaatca cgcctgaaca ggctggagag tttggctttg cttgtggtat gaacatgatg
    42061 cacggcaaga tgattgtaga gtaggtggag actatgacag aaattgtgaa agcaagctta
    42121 gaaaatggca ttcaaaaaat ccgtatccga gctgaaaaag gctatcatcc agcccatatc
    42181 cagcttcaaa agggaattcc agctgagatt acctttcatc gtgctactcc ttcaaactgt
    42241 tataaggaaa ttctgtttga agaagaaggt atcttggaac caatcggcgt agatgaggag
    42301 aaagtcattc gttttacgcc tcaagaatta gggcgacatg aattttcttg tggcatgaag
    42361 atgcaaaagg gaagctatac agtcgttgag aagactcgaa aatctctatc tctcctgcaa
    42421 cgtttttgga ttactagtat ctttactgtg cctcttgtga ttctcatgat tgggatgttg
    42481 gcaggtagca ttagtcatca agtcatgcat tggggaacct ttttagcaac aacgcctatt
    42541 atgttagttg caggtaagcc atatatccag agtgcttggg ccagttttaa aaagcacaat
    42601 gccaacatgg ataccttggt tgcgctggga actctagtgg cttatttcta tagcctagtt
    42661 gctctctttg ctggtctccc tgtttacttc gaaagtgctg gatttatcct ctttttcgtt
    42721 cttttgggag cagtttttga ggaaaaaatg agaaaaaata cgtcccaagc tgtggagaaa
    42781 ttactggact tgcaagctaa aaccgcagaa gtcttgagtg atgatagtta tgtccaagtt
    42841 cctttggaac aagtcaaggt aggcgacctg attcgagtgc gtcccggtga aaagattgct
    42901 gttgatggtg tcgtagtaga aggtgtctct agtattgacg aatccatggt gacaggtgag
    42961 agtctgcctg tggacaagac agttggagat actgtcattg gctcaaccat caatcatagt
    43021 ggaacgcttg tctttagagc agaaaaagtt ggctcagaga ctgttttggc tcagattgtg
    43081 gattttgtga agaaagctca gacaagtcgt gcgccgattc aggacttgac ggataagatt
    43141 tcagggattt ttgtcccagt agttgtcatt ttaggaatca tgaccttttg ggtttggttc
    43201 gtcttgctca gggatagtgt ggtcgtgctt ggagctagct ttgtgtcctc tcttctctac
    43261 ggagtggcgg ttttgattat cgcctgtcct tgtgccttgg gacttgcaac accgacagcc
    43321 cttatggtgg ggacaggacg tagtgccaag atgggggttc tcctcaaaaa tggaactgtc
    43381 ttacaggaaa tccagaaagt tcaaactctt gtctttgata agaccgggac tttgacggaa
    43441 gggaaacctg tggtaacaga tatcatcggt gacgaagtag aagtgtttgg attggcagcc
    43501 tccttggaag atgcttctca acacccactg gctgaggcta tcgttaagcg agcgagtgaa
    43561 gctggacttg agtttcaaac tgttgaaaat tttcaggcct tgcacgggaa aggtgtttca
    43621 gggcgaatca atggaaaaca agttttactt ggaaatgcta aaatgctgga tggcatggat
    43681 atttctaata cttatcaaga taaactagaa gaactagaaa aagaagctaa gacagttgtg
    43741 tttttagctg ttgacaatga aatcaaaggc ttgcttgctt tgcaagatat tcctaaggaa
    43801 aatgctaagc tagccatcag tcagctaaaa aaacgtggtc tccgaacagt catgctgaca
    43861 ggagacaatg ctggtgtggc gcgtgctatt gcagatcaaa tcggaattga agaggtcatt
    43921 gcaggcgtct tgccagaaga aaaagcccat gaaatccata aactgcaaca gtcagggaaa
    43981 gtagcctttg ttggggacgg tatcaatgac gctcctgccc ttagtgtagc agatgtgggg
    44041 attgctatgg gagctggaac agatatcgcc atcgagtcag cagatttggt gttgacaacc
    44101 aataatcttt taggagtggt tcgtgccttt gatatgagta agaaaacctt tcatcgaatt
    44161 ctactcaatc ttttctgggc ttttatctac aatgttgtcg gaattccgat tgcagcagga
    44221 gtcttttcag gtgttggact ggctctcaac ccagaattgg caggtctagc catggccttt
    44281 agttctgtat ctgttctgac cagttccctt ctgttaaatt ttagtaaaat agactaaaag
    44341 taatgactag atttctttgt tataaaacag aaatgacaga actttaaaaa ctgtattaga
    44401 atagagaata gagagttttg agcagatttt tagaaaagtc agcataaata tgatacagtg
    44461 gaatagtaaa aatttggaga acgtttccaa ttctatgtaa tcgtattctc caaatctaaa
    44521 aaaattgaag gagagttatc attatgactc aagggaaaat tactgcatct gcagcaatgc
    44581 ttaacgtatt gaaaacatgg ggcgtagata caatctacgg tatcccatca ggaacactca
    44641 gctcattgat ggacgctttg gctgaagaca aagatatccg cttcttacaa gttcgccacg
    44701 aagagacagg tgctcttgca gcggttatgc aagctaaatt cggcggctca atcggggttg
    44761 cagttggttc aggtggtcca ggtgcgactc acttgattaa cggtgtttac gatgcagcta
    44821 tggataacac tccattccta gcgatccttg gatcacgtcc agttaacgaa ttgaacatgg
    44881 atgctttcca agagcttaac caaaacccaa tgtacaacgg tatcgctgtt tacaacaaac
    44941 gtgtagctta cgctgagcaa ttgccaaaag taattgacga agcctgccgt gctgcaattt
    45001 ctaaaaaagg tccagctgtt gttgaaattc cagtaaactt cggtttccaa gaaatcgacg
    45061 aaaactcata ctacggttca ggttcatacg aacgctcatt catcgctcct gctttgaacg
    45121 aagttgaaat cgacaaagct gttgaaatct tgaacaatgc tgaacgccca gttatctatg
    45181 ctggatttgg tggtgttaaa gctggtgaag tgattactga attgtcacgt aaaatcaaag
    45241 caccaatcat cacaactggt aaaaactttg aagctttcga atggaactat gaaggtttga
    45301 caggttctgc ttatcgtgtt ggttggaaac cagccaacga agtggtcttt gaagcagaca
    45361 cagttctttt ccttggttca aacttcccat ttgctgaagt ttacgaagca ttcaagaaca
    45421 ctgaaaaatt catccaagtt gatatcgacc cttacaaact tggtaaacgt catgcccttg
    45481 acgcttcaat ccttggtgat gctggtcaag cagctaaagc tatccttgac aaagtaaacc
    45541 cagttgaatc aactccatgg tggcgtgcaa acgttaagaa caaccaaaac tggcgtgatt
    45601 acatgaacaa actcgaaggt aaaactgagg gtgaattgca attgtatcaa gtttacaatg
    45661 caatcaacaa acatgctgat caagacgcta tctactcaat cgacgtaggt aacactactc
    45721 aaacatctac tcgtcacctt cacatgacac ctaagaacat gtggcgtaca tctccactct
    45781 ttgcgacaat gggtattgcc cttcctggtg gtatcgctgc taagaaagac aatccagatc
    45841 gccaagtatg gaacatcatg ggtgacggag cattcaacat gtgctaccca gacgttatca
    45901 caaacgttca atacgacctt ccagttatca accttgtctt ctcaaatgct gagtacggct
    45961 tcatcaagaa caaatacgaa gatacaaaca aacacttgtt tggtgtagac ttcacaaacg
    46021 ctgactacgc taaaattgcg gaagctcaag gagctgttgg attcacagtt gaccgtatcg
    46081 aagacatcga tgcagttgtt gcagaagctg ttaaattgaa caaagaaggt aaaactgttg
    46141 tcatcgatgc tcgcatcact caacaccgtc cacttccagt agaagtactt gaattggatc
    46201 caaaacttca ctcagaagaa gctatcaaag ccttcaagga aaaatacgaa gcagaagaac
    46261 tcgtaccatt ccgtctcttc ttggaagaag aaggattgca atcacgcgca attaaataat
    46321 tcctctcgcc gaaaatcaaa tatgaaactt gtagacttta ttctttgatt ttcatagagc
    46381 agaactttaa aagatcggag caatccggtc tttttatgga ggagagtaaa tgaatttaaa
    46441 tcaattagat attatcgttt caaatgttcc ccaagtctgt gctgacttgg agcatatttt
    46501 ggataaaaag gcagattatg ctgatgatgg ttttgctcag tttacgattg gtagtcactg
    46561 ccttatgttg tcacaaaatc atttggttcc tttggaaaac tttcagtcag gaatcattat
    46621 tcatatcgag gttgaggatg tagaccagaa ctacaaacgg ttgaacgagc ttggtataaa
    46681 ggttttacac ggaccaactg taaccgattg gggaacagag tccttattag ttcaaggacc
    46741 tgctggtcta gtgcttgatt tttatcgtat gaaataggtc gcgtagtcat ttgacgttaa
    46801 ccttagctat ttttaaaata gaaattgaga atatgaacta ttgaaagatc ggagcaatcc
    46861 ggtcttttta tataaagaaa ttgcatataa tactcatatg ctttcaaaaa gcattctagt
    46921 ccatctccga ttaacgatgg actttatcac ctccttctcc agtccttgta tgacatcttg
    46981 aagttgattc atgacatctt ccaaagttcg aaaggcctta ttcttaaatc cacgtttacg
    47041 aatctctttc cacacttgtt caatgggttc atctctggtg tgtatggagg aataaaggta
    47101 aaaccaatat tagtcggaat ctttaaggta cttgatttat gccatatagc attgtccata
    47161 acgagtaaaa gataatcatc tggataagct tgtgaaagct cttctaaaaa ggcgttcatc
    47221 cactcagtat tacatccacc agctattaag aaaaatgatt cgcctgtatg ggcatcaaca
    47281 gctccataac aatagtgaaa ttctcgtata tagtgactat ggacatgtgg acctactcct
    47341 attggagccc aacaagatcc cagtttactg attctaccga aaccagcctc atcttggtac
    47401 atcaagcgaa ccttacgaaa acgtctactg cttttaaagc gctttctttt cttcttgaat
    47461 tgagatttta tttttagacg cgacaatggt ttgagcgtct gctttcctag gatgttctgg
    47521 acgtggcata atatttcgcc aaccatggcg cttcaacagt tgatagaagg catcacgtgt
    47581 gtaggaacga cctaactcct ttttataagc ctgaaataag gcatcaattg taacaaattc
    47641 tcctgcctct gtagccttca aatggcgggc aagaaagact ttcttttcct caatcgtcat
    47701 atatgcatgg ttacggccac cacgtgtttc ttgaaggaga gagtcgagtt cgaactcctc
    47761 atattttttt acatttcgcc aaatcgttgt ttgattacag tctatagtgt attgaatcta
    47821 taacagtaca ccttagctgc taaaatattt ctataaatta gtttgacttt cctgatagag
    47881 ttgttcacat cttatttcaa actactataa aagttctata atctctttat aagatttgcc
    47941 catcagacga aatataataa attgaaacta gaatagtaca cctctacttc taaaacattg
    48001 ttagaaatcg atttgactgt cctgatcgat ttgccctgtt cttgtttcgt tttactatag
    48061 aacgatttga aggcgtttat gatatttagc tgtacgagag tctttaaaaa gtgttttgat
    48121 ggtttggatt tcttctttag ttgatttcat atcactatta tataatgctt tttgatttta
    48181 gtatagtatt atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta
    48241 tgtagcagat gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc
    48301 catttacaaa gacggggttg acttgcttgg ttatacgaca tggggctgta tcgattcggt
    48361 ttcagctggc acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa
    48421 tgtaggaaat gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt
    48481 tatagcaatg gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc
    48541 tccctgcttt ataagatgta aaaaagagtt caattcgaac tctttttttg ctataatgag
    48601 gggagaaaaa tcagacagga gatcgacatg tcagaaccat tatttttaca atcagttatg
    48661 caagaaaaaa tctggggtgg agccaagcta cgtgatgagt ttggctacga catcccaagt
    48721 gaaaaaatcg gagaatattg ggccatctca gcccatccaa atggagtctc taaagttgcc
    48781 aatggtcgtt acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt
    48841 ggcaatcgtc cagaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg
    48901 ctcagtgtcc aagttcaccc agacgatgct tatggactcg agcatgaagg cgaactcgga
    48961 aaaacagaat gctggtacat tatcgcagcg gatgaaggtt cagagattat ctacggtcac
    49021 aatgccaagt caaaagaaga actccgccag caaatcgagg acaagaactg ggatgacttg
    49081 ttgaccaaag tccctgttaa ggctggagat ttcttctatg taccaagcgg gactatgcac
    49141 gctatcgggg cgggtatctt aatccttgaa acccagcagt ctagcgatac cacctatcgc
    49201 gtctatgact ttgaccgcaa ggatgacaaa ggcaacttgc gtgaacttca tcttgaaaaa
    49261 tccatcgatg tcttgaacat tggtgagcca gcaaatagcc gtcctgtaac tgttaaagca
    49321 gatgatttgc gttccactct ccttgtatct aatgatttct tcgcagttta caagtgggaa
    49381 attactggaa aagttgactt tgaaaagaca gctgactaca gcttattgag tgtcttagct
    49441 ggtcaaggtc agctaactgt tgacgggaaa aattatccaa ttcaaaaagg gagacacttt
    49501 atcctaccaa gtgatgttga agcttggact ctggaagggc aaggtttgga attgattgtt
    49561 agccatccat aaaaagaaag ggcctgagtt cactactcaa gtcctttttg attacataaa
    49621 ttgggcaatg aagaccacaa tgatgatgat tggaatgacg aaacgaagaa acgaagaaac
    49681 gaagaaggaa gagccagact tggaacagtc cttgtttcca tgctctttca tcgagatgga
    49741 gttcctccat tgcaagagcc tttttaaaga tatagcctgt aaaaagtgaa aggtagagag
    49801 ctccaaatgg catgaggaga ttggaagcca agaagtccat agcgtcaaag aagatcttac
    49861 caaaaatgtg aacatccgcc atgacaccgt aagatagggc tgaaggaatg ccaaagacaa
    49921 aggtcaaaat tcctaaaata acactccatt tggcacgttt gctgttatcc tggttggtga
    49981 tattgcccac attgatctcc agcatcacga cagaagaagt gacagtcgca aagaggaaaa
    50041 ggacgtagaa aatggttcca aaaggcatct tgtcaaagag ttgaggcaag acgataaaga
    50101 gcaagctcgg tcccccttca atatccagtc tgaaggggga ccgagcttgg aaaatggcta
    50161 gacctgccat gatggatatc gagatattca tggctacgat ggagattcct gactggacta
    50221 gattggtttt cttgtccaag taagaagcat aggtcagcat gactgtaacc cctagtgaga
    50281 gggcaaagaa agattgtccc agagcataga ggggaccagc gctagtcagt tttgaaaagt
    50341 ctggtttgag gaagtaaaga accccttcca tggcatttgg caaactggga gagcgttcga
    50401 tgatgacgac aaagatgata aagagcaggg gcatcatgac tttcgaagct ctttcaatcc
    50461 ctttttgaac cccacgtgat acaataaaga tatttaataa gataaaggct gcttgagctc
    50521 ctagggcaat ggctggattt gaaatgattg aagtaaataa ctgagcataa tcacccgttc
    50581 caccaagttg gaacaatttc ccaaactcaa tacctagata gactagaatc catcctccga
    50641 taacactgta aaaagataag aggataaaga gggcaaaggc gccaatccaa ccgataaagt
    50701 tgtacttgtt attcttgccc agttttccaa aggttttgat agcggaaacg ccagcactac
    50761 ggccaagggc aaactcagcc agcaggagag ggaaatcgat taaaatagtg gaaatgagaa
    50821 agattagtaa aaagcctcca ccgccattag cagcagtcat gtagggaaac ttccaaacgg
    50881 caccaagccc gatggccagc cagcagatgc tagaataaaa ccaagtttcg acccccattg
    50941 tgatttttct gacatagtta aactctgatc tcctttttca aaataagaaa aagctacttg
    51001 agttgtcaaa tagccttctg tttgattgat agacttgact atcctattat gttttctaag
    51061 gtctgtcaag aaaaccattt tcaagttttc acacctttct caaaaacgct tgactctgac
    51121 ctaaggggag gggttatact atcattgtaa ggaggaaatc atgtaccata taaaagaagc
    51181 tgcgcagctt tcaggtgtct ctgtcaagac cctgccctgc atcactatga caagatagga
    51241 ctcttggtcc ccttaaagtc ggaaaacggc tatcgaacct atagtcaaga ggatttggaa
    51301 cgccttcagg tcattcttta ctacaaatat ctaggctttt ctttagagaa aatagcagag
    51361 ctgttaaagg aagaaaggac agatttattg ccccatttaa ctaggcagtt ggactatcta
    51421 actcgcgaaa ggcaacatct ggataccttg atttccacct tgcaaaaaac tattcaagaa
    51481 caaaaaggag aaagaaaaat gaccattgag gaaaaattca cgggatttag ctatcaagac
    51541 aatcaaaaat accaccaaga agcggtagag aaatatggtc aagaagtcat gggacaagcg
    51601 ctcgaacgcc aaaaaggtca cgaagacgag gctacggccg cctttaacca agtctttcaa
    51661 actttggcac aaaatcttca agttggttta cctgcaacag caaccgaaaa ccaagagcaa
    51721 gcagccaagc tcttgcaagc tattcgcact tatggatttg actgctctat tgagatattc
    51781 ggtcatatcg gtaaaggtta cgtctacaac ccagagttta aggaaaacat tgacaagttt
    51841 ggttctggaa cagcccagta cacgtcagat gccattgcgg cttacgttca gacaaatgca
    51901 gaataaatag gctaggaatt tcctagccta ttttttactt caaatcataa agccagtcgt
    51961 caccgttttt gtagtaaaag aattcactga gatcttcttc tagaaacaca cgaagcatat
    52021 cagacatatc atcggttgca agttttagat gagaaagatt ttcaaagtcc tcccaccaaa
    52081 ctttcccttc gtctgaagac tggagttcac cagtaaagtg ttctgtcttg taaaaaagga
    52141 cgacataacg ataatccttg tcgtcatacc agtttttaat accacagagt tggggtttgg
    52201 aaatgatcag accagtttct tctttcactt cacgaatgac agcatcgaca aaggattcgc
    52261 cacgttcaac atgaccacca ggaaaagtaa tgccaggcca gtcgggacta actcggtctt
    52321 ggaccaggat cttatctccg tttttaatca tacacatgtt aacaaattcg actgcctctc
    52381 ttctgttcat tcttcacaac ctttaatctt taatcataat gcagacttcc cgccacccag
    52441 ccggtacaga gagcagaagt gatgttaaag ccacccgtgt gggcattgat atccataact
    52501 tcgcctgcaa agtggaggcc aggtaccagc ttactttcaa gggttttagg attgatttcc
    52561 ttgagactga ctccaccctt ggtaacaaag gactttgcaa gggacatttt tccagttaca
    52621 ggaattttaa gttctttaat ggactggaca agttgttctc gttccttttc agtcagctgt
    52681 ttgacttttt caggatatcc ttgtacaaaa aattcggcca agcgttctgg taacaaggtt
    52741 tttaaagcgt ttttcaagga tttttcccga ttttcttcta gaaatgtaac caagtccttc
    52801 tcagaaagtt gaggcaaaac atcgagtgag agaacctccc cacctttgac caagctagac
    52861 atgcgtaggg cagcaggacc tgacaaacca aagtgggtaa agagtaaatc atgagtgatg
    52921 acatgcttac cataacttag ggtcacatcg tccagagaaa tcccttgtaa ggctttatgt
    52981 ggaaaatctg ttaataaagg actttcagca gcctcaagat cggtgatggt atgcttaaaa
    53041 tggcgagcaa tctcgtgacc aaaaccagtc gaaccagtcg aaggataaga cttaccacct
    53101 gttgtgacaa tgagtttctc acaagtgaag gtttgatccg ctgacttaag gacaaactgg
    53161 tcatctactt ttttaacaga aacgatttct atttgagtag caacttgacc acctagttca
    53221 gtgattttct tttccaaagc ttcgataata gtccgagact tgtcactggc tggaaagacg
    53281 cgtccgtggt cttcgacctt aagtttaaca ccattttctg taaaaaagtt gatgatgtca
    53341 tgattatcga actgggagaa aacactgtaa agaaagcgtc cgtttccagg aattccagct
    53401 agcaggttgt ctaagctacc attgttggtc acattgcaac gtcccccacc agtcccagct
    53461 aatttttttc caagtttccg atttttttcg atgaggaggg ttttctgtcc ataaaagcta
    53521 ctggaaatcg tagccatcat accagcaggt cccccaccga tgacaatagt atcaaaatgt
    53581 ttcatagctc tattgtacca caaaaaaaca agagatgatg gtcacctctt gtcaagaatg
    53641 caattaatca atttcatagc ccatcagcaa accgccctct tctgcataga aactgcagag
    53701 accagaggtt ggtagaattt taatatccgc ttgtgggaag gtttcacgga ttcgctctga
    53761 gagctgttga caacattttt cgttattgcg ttgggccatg acaatacggc caccagcata
    53821 tccagctttt actaactcat cataggcagc ttgaactgat ttctttgatc cccttgcttt
    53881 ttgtagcaat tcgagagtcc cagtttcact agcttttccg accatacgaa tgttgagaag
    53941 gccaacgacc gtaccgataa gcttgctcaa acggccgttc ttcaccaagt tatcgacttt
    54001 ggctaggaca aagagcaact tagttttttc ttgataggcg gtgatagctt caaccacttc
    54061 ttcaaaagac aagccctggt caatcaagtc attcaatttt tctacgagta ggtcaacttc
    54121 accaccagca gataaactat caatcacatg aatcttagtg tcaggatggt cttccagata
    54181 aatattcttt gctagttgag cactattgtg actgccagaa agggtacctg tgatggttac
    54241 taggaaaatg tttttggcac cttcaaatgc tcgcaaatag tcatctgggc ttggacaagc
    54301 cgattttgaa gcttctgcag ttgcatacat ggtttccatc atttggtcaa tatcgagact
    54361 ggcgtcatca acaaagacct gatcagctac ttgaatggtt aaggggacgc ttacaaaggt
    54421 tgtgttaata gctggtgttg gcagttgacg ataatcacaa ccagagtcag caataatttt
    54481 ccaagtcata gaaattctcc atctttgtca gttatacatt gacaaaggtt ctgtcttttt
    54541 ttacaattat atcatgaaaa cccttgaaac aaaagcatca tccgtctgtt gtgacaagta
    54601 gaaagaaaat gttatgtctg aacgtagaat ctctgaaaag tctcttgaaa atctcagaaa
    54661 atcaaaccaa gaatccaatt tattaaccag agaagccatt gaaacagccc tcttgcaact
    54721 cttggaaaaa aaggagctga ccaagattag tatttctgaa ttggtcaaac gtgcgggtgt
    54781 ttcgcgtgcg gccttttatc gcaattatga ctccaaagag gaaattttag agagcgtctt
    54841 taaacgaact gtccacaata ttatggaaca gctgcatcat tacgatttaa agacagacct
    54901 ttatttggtt tgggttcacc ttttccggga ggccagaaag gaagctagag tgattcaatt
    54961 ggccttggat taccatctgg aaaaaatctt tgtccaagcc atgcaggaat ttctagaaaa
    55021 ataccatggg aaatcaaaag gtgtcagctc ttatcttcat tccttctgga gctcagccat
    55081 cgtctctgtc cttctaaaat ggatcaagga tggcatgaag gtaccagctg aaaagattgc
    55141 agatttaggt ttaccatttt ttaaaaaata gagaaaaagg agaaaagaga tgactgaaaa
    55201 aagactggcc tgggatgagt attttgcagc ccaagcccta ctaattgcga atcgttccac
    55261 ttgtaaacgt gctaaagtgg gcgcgattct ggtaaaagat aataaggtta tttccactgg
    55321 ttacaatggt tcggtgtcag ggactgagca ttgtattgat cacgaatgtt tggtcattga
    55381 aggccactgt gttcgcaccc ttcacgctga ggtcaatgct atccttcaag gtgctgagcg
    55441 tggtgttccc aaaggcttta cagcctatgt aacccatttt ccttgtctca actgtacaaa
    55501 acaattgctt caggtcggct gcaagcgtgt ggtttatatc aaccagtacc gaatggacga
    55561 ctacgcccaa tacctttatc aagaaaaagg gacagaattg acccatttac cacttgagac
    55621 agtacagaca gctcttaaag aggctgatct aatgtaaaaa ttatcaaaaa taaatggttt
    55681 agaaagattt ttaaaccgtt ttttggtata ataagaagaa taaattgaaa gaaggaattc
    55741 caaaaatggg aaaaattgaa gttattaatc acccactgat tcaacacaaa ttgtcaatct
    55801 tgcgtcgtac agatacttct acaaaagctt ttcgtgagct agtagatgag attgcaatgt
    55861 tgatggggta tgaagtactt cgtgatcttc cactagaaga tgtggaaatc gaaacaccaa
    55921 ttacaaaaac agttcaaaaa caattggcag gtaagaaatt ggccatcgtc ccaatcttgc
    55981 gtgcaggtat cgggatggtt gatggtctct tgaacttggt tccagctgct aaagttggcc
    56041 acatcggtat gtaccgtgat gaagaaacac ttcaaccagt tgaatacttg gtgaaattgc
    56101 ctgaggacat tgaccaacgt caaatttttg tagtagaccc aatgttggca acaggtggct
    56161 cagcaatctt ggctgttgat tctcttaaaa aacgtggcgc atcaaatatc aaatttgtct
    56221 gccttgtatc tgctccagag ggtgtaaaag cccttcaaga agctcatcca gatgtagaaa
    56281 tctttacagc agccttggat gaacgtttga acgaacacgg ttatatcgtt ccaggtcttg
    56341 gagatgctgg agaccgcttg ttcggtacaa aataagatcg aaaagaagaa tgacttggaa
    56401 aagtatttcc agtcacgaaa ggaggttggg tttttgtttc tgtctaatga aagcagagca
    56461 aaaatttgac cttttttgac caagatatta taatagtctt atcttcagtc atttgaccaa
    56521 caaaattaaa actcaaaagg agaaatgaat gattcctgta gttattgaac aaacaagccg
    56581 tggagaacgt tcttacgata tttactcacg tcttctcaaa gaccgcatca ttatgctgac
    56641 aggtccggtt gaagacaata tggctaactc tgttattgcc caactgcttt tcttggatgc
    56701 ccaagatagt acaaaagata tttaccttta tgtcaataca ccaggtggtt ctgtttcagc
    56761 tggtttggca atcgtagata ccatgaactt tatcaaggca gatgtccaaa ccattgttat
    56821 gggaatggct gcatctatgg gaacagtcat cgcatcaagt ggagcaaaag gcaaacgttt
    56881 catgcttcca aatgctgaat acatgattca ccaaccaatg ggcggtacag gtggtggtac
    56941 ccaacaaact gatatggcta tcgctgcaga acacttgctc aaaactcgta ataccttgga
    57001 aaaaatcttg gctgaaaatt caggtcagtc aatggaaaaa gtccatgcag atgcagaacg
    57061 tgataactgg atgagcgccc aggaaacact tgaatatggc tttattgatg aaattatggc
    57121 caacaattca ttgaactaat gatgatagaa ggcaaactcg actgggtttg ctttttttgg
    57181 tataataggg agagatttct tagaaagagg atttatcatg tttgaaaaag tcaatcgctc
    57241 tggcttgatt atctatcttt actataatcg tgatgccaaa aaactgcagg attatggaga
    57301 tattacctat cattccaaga aacatcgtta cttacaactc tatgttccaa ctcaagaagt
    57361 ggagcaattg gtcggacgct tgagcaagga aaaatttatt aaaaaagtta gggtttgtca
    57421 tatccaagag ttggaaacac cctttgtggg caatctttat cgataggaaa acgctatcat
    57481 cgaaaaagtt caaggaaaac attgacaatt ttctgataat tcggtatatt cttaacagac
    57541 tatttaagaa ataaggagac aaaaaagatg aagaaaaaat ttgccctatc gtttgtggcg
    57601 cttgcaagtg tagcacttct tgcagcctgt ggagaagtga agtctggagc agtcaacact
    57661 gctggtaact cagtagagga aaagacaatt aaaatcgggt ttaactttga agaatcaggt
    57721 tctttagctg catacggaac agctgaacaa aaaggtgccc aattggctgt tgatgaaatc
    57781 aatgccgcag gtggtatcga tggaaaacaa atcgaagtag tcgataaaga taataagtct
    57841 gaaacagctg aggctgcttc agttacaact aaccttgtaa cccaatctaa agtatcagca
    57901 gtcgtaggac ctgcgacatc tggtgcgact gcagctgcgg tagcgaacgc tacaaaagca
    57961 ggtgttccat tgatctcacc aagtgcgact caagatggat tgactaaagg tcaagattac
    58021 ctctttattg gaactttcca agatagcttc caaggaaaaa ttatctcaaa ctatgtttct
    58081 gaaaaattaa atgctaagaa agttgttctt tacactgaca atgccagtga ctatgctaaa
    58141 gggattgcca aatctttccg cgagtcatac aagggtgaaa tcgttgcaga tgaaactttc
    58201 gtagcaggtg acacagactt ccaagcagcc cttacaaaaa tgaaagggaa agactttgat
    58261 gctatcgttg ttcctggtta ctataatgag gctggtaaga ttgtaaacca agcgcgtggt
    58321 atgggaattg acaaaccaat cgttggtggt gatggattca acggtgagga gtttgtacaa
    58381 caagcaactg ctgaaaaagc atcaaacatc tactttatct caggcttctc aactactgta
    58441 gaagtttcag ctaaagctaa agccttcctt gacgcttacc gtgctaagta caatgaagag
    58501 ccttcaacat ttgcagcctt ggcttatgat tcagttcacc ttgtagcaaa cgcagcaaaa
    58561 ggtgctaaaa attcaggtga aatcaagaat aaccttgcta aaacaaaaga ttttgaaggt
    58621 gtaactggtc aaacaagctt cgatgcagac cacaacacag tcaaaactgc ttacatgatg
    58681 accatgaaca atggtaaagt tgaagcagca gaagttgtaa aaccataata gaaaaatgtt
    58741 gaaataggga atgagccttt gactcactcc ctgtttcgat atttaatact cttcgaaaat
    58801 ctcttcaaac tgcgtcaacg tcgccttgga ttatatatgt gactgacttc gtcagtctta
    58861 tctacaacct caaagcagtg ctttgagcaa cctgcggcta gtttcctagt ttgctctttg
    58921 attttcattg agtataagaa cctatcaaaa agtgagggaa acccctcgga attataaata
    58981 gaaagagtga atcttatgct ccaacaactc gtaaatggtt tgattctagg tagtgtttac
    59041 gcgctgttag ccctaggata taccatggtt tacggaatta tcaagctcat caacttcgcc
    59101 catggtgata tttatatgat gggagccttt atcggttatt tcttgatcaa ttctttccaa
    59161 atgaatttct ttgtagcgct tattgtagct atgctagcga cagctattct tggtgtcgtg
    59221 attgagtttc ttgcttaccg acctttgcgc cactctactc gtattgctgt tttgattacg
    59281 gctattgggg tttctttcct attggagtat ggaatggtct atctggttgg tgccaatacc
    59341 cgtgccttcc ctcaagcgat tcaaacagtt cgatatgatt tgggaccaat tagcttaaca
    59401 aatgtgcagt taatgatttt ggctatttcc ttgattttga tgattttgtt acaagtcatt
    59461 gtccaaaaga ctaagatggg gaaagccatg cgtgcagtat cagtagatag cgacgcggcg
    59521 caattgatgg ggatcaatgt aaaccgtacg attagcttta ccttcgcttt gggttctgct
    59581 cttgcgggtg cggctggtgt tctgattgct ctttattata actctcttga gcctttgatg
    59641 ggggttactc caggtcttaa atctttcgtt gccgcagtac ttggtggtat cggaattatt
    59701 cctggtgcgg ctcttggtgg ctttgtgatt ggtctattgg aaacctttgc gactgccttt
    59761 gggatgtcag atttccgtga tgccattgtt tatggaatct tgttgttgat cttgattgtc
    59821 cgcccagctg gtatccttgg taagaatgtg aaagagaagg tgtaaacgat gaaggaaaat
    59881 ttaaaagtta atattctatg gttactcctt ttgttagctg gctatagctt gattagtgta
    59941 ctggtttcag tcggagtact taatctattc tatgtacaga ttttacagca aattggaatt
    60001 aatattattt tggctgttgg tctcaactta atcgttggtt tttcaggaca attttcactt
    60061 ggtcatgctg gtttcatggc gattggtgcc tatgcagcag ctattattgg ttctaaatta
    60121 ccaacctacg gtgccttctt tggagctatg cttgtagggg ctttgctttc aggagcagtt
    60181 gccttacttg tcggcattcc aaccttgcgc ttgaaggggg actatcttgc ggtagcaact
    60241 ctgggtgttt ctgaaattat ccgtatcttt atcatcaatg gtggaagcct tacaaatggt
    60301 gcggcaggta tcttagggat tcctaacttt acaacttggc aaatggttta cttctttgtc
    60361 gtgattacaa ccattgcaac cttgaacttc ttgcgtagcc caattggtcg ttcaaccctc
    60421 tctgttcgtg aagatgaaat cgctgctgag tcagttgggg ttaatacgac taaaattaaa
    60481 atcatcgctt ttgtctttgg tgccattact gcaagtattg ctgggtcact tcaggcagga
    60541 tttatcgggt ctgttgtacc gaaagattac accttcatca actcaatcaa cgttttgatt
    60601 attgttgtat ttggtggact cggttccatt acaggtgcga ttgtttcggc tattgttctg
    60661 ggaattttga atatgcttct ccaagatgtt gctagtgtgc gtatgattat ttacgctttg
    60721 gccttggtat tggtaatgat tttcagacca ggtggactcc ttggaacatg ggaattgagc
    60781 ctatcacgtt tctttaaaaa atctaagaag gaggaacaaa actaatggca ttacttgaag
    60841 taaaacagtt aaccaaacat tttggtggtc taacagctgt tggagatgtg actcttgaat
    60901 tgaacgaagg ggaactggtt ggattaatcg gtccaaacgg agctgggaaa accacccttt
    60961 tcaacctttt gaccggtgtt tatgaaccaa gtgagggaac agtaacccta gatggtcacc
    61021 ttttgaatgg gaaatcacct tataagattg cctctttggg acttggacgt actttccaaa
    61081 atatccgtct ttttaaagat ttaacagttt tagacaatgt tttgattgct tttggaaacc
    61141 atcacaaaca gcatgttttt actagtttct tacgcttacc agctttttac aagagtgaaa
    61201 aagaattaaa ggttaaagct ttggaattgt tgaaaatctt tgatttagat ggtgatgcag
    61261 agactcttgc taaaaatctt tcctacggac aacaacgtcg tttggaaatt gttcgtgccc
    61321 ttgctacgga acctaaaatt ctcttcttag atgaaccagc agcaggtatg aacccacagg
    61381 aaacagccga attgactgag ttaattcgtc gtatcaaaga tgagtttaag attacaatca
    61441 tgttgattga acacgatatg aatctggtca tggaagtaac agaacgtatc tacgtacttg
    61501 aatatggccg tttaatcgct caaggaactc cagacgaaat taagaccaat aaacgcgtta
    61561 tcgaagctta tctaggaggt gaagcctaat gtctatgtta aaagttgaaa atctttctgt
    61621 gcattacggt atgatccaag cagttcgtga tgtaagcttt gaagttaatg aaggagaagt
    61681 tgtttccctt atcggtgcca acggtgcagg taagacaact attcttcgca ccttgtcagg
    61741 tttggttcga ccaagttcag gaaagattga atttttaggt caagaaatcc aaaaaatgcc
    61801 agctcagaaa atcgtggcaa gtggtctttc acaagttcca gaaggacgcc acgtctttcc
    61861 tggcttgact gttatggaaa atcttgaaat gggagctttc ttaaagaaaa atcgtgaaga
    61921 aaatcaagct aacttgaaga aggttttctc acgctttcct cgtcttgaag aacggaagaa
    61981 ccaagatgca gccactcttt caggggggga acaacaaatg cttgccatgg gacgcgccct
    62041 catgtcaaca ccaaaacttc ttcttttaga tgaaccatca atgggacttg ccccaatctt
    62101 tatccaagaa atttttgata tcattcaaga tattcagaag caaggaacaa cggtcctctt
    62161 gattgaacaa aatgccaata aagcacttgc aatctctgac cgaggatatg tactggaaac
    62221 agggaaaatc gtcctatcag gaacaggaaa agaactcgct tcatcagaag aagtcagaaa
    62281 agcatatcta ggtggctaaa acaatccagt ggattgtttt agtcggcaga tggagattac
    62341 gaagtaatca tcaatatagt ccgggggacc tttttagtcg gtagattgag attgcaaaca
    62401 aatctgcatc tacattgaaa gcttaatttc taataattga aaaaatcgaa tgaaaaattt
    62461 cttactgaaa gttctataat gaagttagcc accttacctt agtcaagaat tagatgtttc
    62521 actatgtttg agtaagttga tgatttcatt tgataacagg tttgaaactg ttaggctagg
    62581 tggccaaggc taatcatagc cttggtttag ctgaaaaaac aggttcaagg gttcctgttg
    62641 tcaaatgaaa tgtgatttaa ggtataagaa aacacctctg tgctatactt gttgttcacc
    62701 acaaacac
//
LOCUS       DAVEHY010000007        62339 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVEHY010000007 DAVEHY010000000
VERSION     DAVEHY010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.007"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..219
                     /locus_tag="VUZ44_000565"
     CDS             <1..219
                     /locus_tag="VUZ44_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU0319526.1"
                     /translation="NSKPQADDKKPSTTNNLSKDKQPSNQASTNEKATNKPKKSLPST
                     GSISNLALEIAGLLTLAGATILAKKRMK"
     gene            complement(438..1418)
                     /gene="dusB"
                     /locus_tag="VUZ44_000566"
     CDS             complement(438..1418)
                     /gene="dusB"
                     /locus_tag="VUZ44_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU0319527.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKV"
     gene            complement(1405..2277)
                     /gene="hslO"
                     /locus_tag="VUZ44_000567"
     CDS             complement(1405..2277)
                     /gene="hslO"
                     /locus_tag="VUZ44_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU0319528.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIETLLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2442..3869
                     /locus_tag="VUZ44_000568"
     CDS             2442..3869
                     /locus_tag="VUZ44_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0319529.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLFY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            4028..5536
                     /gene="glpK"
                     /locus_tag="VUZ44_000569"
     CDS             4028..5536
                     /gene="glpK"
                     /locus_tag="VUZ44_000569"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU0319530.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5578..7404
                     /gene="glpO"
                     /locus_tag="VUZ44_000570"
     CDS             5578..7404
                     /gene="glpO"
                     /locus_tag="VUZ44_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU0319531.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7474..8178
                     /locus_tag="VUZ44_000571"
     CDS             7474..8178
                     /locus_tag="VUZ44_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU0319532.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8475..8678
                     /locus_tag="VUZ44_000572"
     CDS             8475..8678
                     /locus_tag="VUZ44_000572"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319533.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8765..9373)
                     /locus_tag="VUZ44_000573"
     CDS             complement(8765..9373)
                     /locus_tag="VUZ44_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319534.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10515..10916
                     /locus_tag="VUZ44_000574"
     CDS             10515..10916
                     /locus_tag="VUZ44_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase/maturase"
                     /protein_id="HEU0319535.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPILKVEIPKPDGGIRQLGISTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYE"
     gene            10920..11231
                     /locus_tag="VUZ44_000575"
     CDS             10920..11231
                     /locus_tag="VUZ44_000575"
                     /inference="COORDINATES: protein motif:HMM:NF012307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319536.1"
                     /translation="MDIDLEKFFDTVPQDRLMSLVHNIIEDGDTESLIRKYLHSGVII
                     NGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLRFVRYADDCVIRSEARQPLS
                     V"
     gene            11282..11791
                     /locus_tag="VUZ44_000576"
     CDS             11282..11791
                     /locus_tag="VUZ44_000576"
                     /inference="COORDINATES: protein motif:HMM:NF019984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319537.1"
                     /translation="MTKTKITRPRELKYLGFGFWKSSDGWKSRPHQDSVRRFKFKLKK
                     LTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMKSIVASIDERLRTRLRVIIWKQWKK
                     KSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYY
                     LERHALKVS"
     gene            12248..13426
                     /locus_tag="VUZ44_000577"
     CDS             12248..13426
                     /locus_tag="VUZ44_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU0319538.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13740..13871
                     /locus_tag="VUZ44_000578"
     CDS             13740..13871
                     /locus_tag="VUZ44_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU0319539.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13892..15442
                     /gene="dltA"
                     /locus_tag="VUZ44_000579"
     CDS             13892..15442
                     /gene="dltA"
                     /locus_tag="VUZ44_000579"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU0319540.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15439..16683
                     /gene="dltB"
                     /locus_tag="VUZ44_000580"
     CDS             15439..16683
                     /gene="dltB"
                     /locus_tag="VUZ44_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU0319541.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16697..16936
                     /gene="dltC"
                     /locus_tag="VUZ44_000581"
     CDS             16697..16936
                     /gene="dltC"
                     /locus_tag="VUZ44_000581"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU0319542.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16929..18197
                     /gene="dltD"
                     /locus_tag="VUZ44_000582"
     CDS             16929..18197
                     /gene="dltD"
                     /locus_tag="VUZ44_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU0319543.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18352..18792
                     /gene="adcR"
                     /locus_tag="VUZ44_000583"
     CDS             18352..18792
                     /gene="adcR"
                     /locus_tag="VUZ44_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU0319544.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18792..19496
                     /locus_tag="VUZ44_000584"
     CDS             18792..19496
                     /locus_tag="VUZ44_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU0319545.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19489..20295
                     /locus_tag="VUZ44_000585"
     CDS             19489..20295
                     /locus_tag="VUZ44_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU0319546.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20305..21810
                     /gene="adcA"
                     /locus_tag="VUZ44_000586"
     CDS             20305..21810
                     /gene="adcA"
                     /locus_tag="VUZ44_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU0319547.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQSLDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKVLTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQETLFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22981..23754)
                     /locus_tag="VUZ44_000587"
     CDS             complement(22981..23754)
                     /locus_tag="VUZ44_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU0319548.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            23930..25333
                     /locus_tag="VUZ44_000588"
     CDS             23930..25333
                     /locus_tag="VUZ44_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU0319549.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSTLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEDSLFISSGTWSLVGVELSSPILSTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETGEWTDGQLFKIVYESLAETYKETIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEATAVGNICIQLLSQGKINEDTGLK
                     DIMTNIADTQYYYPQLS"
     gene            25362..26654
                     /locus_tag="VUZ44_000589"
     CDS             25362..26654
                     /locus_tag="VUZ44_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0319550.1"
                     /translation="MNKKSLLKCAVIGLVATFGLAACGTSKDASGGSSSGKEVLEFYH
                     GYHHSEDEWPVAKTMRDLYDKFAEEHKDSGVEFKPTPVNGDLKDIMNNKVASGEFPDV
                     IDLAGNAVSLAAIEQKLVLDLKPYIDSNKLEKNVGLNYKQNQKDGKIYTVHEQLFTMG
                     LWYNKDIFAKAGAKTPDQWNTWEDFTQAMAAVRKQDGVYAFGAGEPSIRLFNTVLGTT
                     ENGRKLLDKPLTKEGIESKEFADALKMVMKEIQANGSKNAGGDANAYSKDFQEGKSAV
                     FFNGVWASGEMSKNPSLAPGIYPAGVAISSSGGGITISSKMSEAKQKLALEFLKYMTS
                     DDVQKVIFEKVGANPSNENVNVKELSEKSSEATTKILGQAITQVKNAKAVVPTVSDVW
                     GGDVHTAIINALTESAAENVDVDQKVKSTQDVLKSLIG"
     gene            26741..27670
                     /locus_tag="VUZ44_000590"
     CDS             26741..27670
                     /locus_tag="VUZ44_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU0319551.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            27673..28512
                     /locus_tag="VUZ44_000591"
     CDS             27673..28512
                     /locus_tag="VUZ44_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU0319552.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPTDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            28509..29828
                     /locus_tag="VUZ44_000592"
     CDS             28509..29828
                     /locus_tag="VUZ44_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU0319553.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            29834..31705
                     /locus_tag="VUZ44_000593"
     CDS             29834..31705
                     /locus_tag="VUZ44_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
                     /protein_id="HEU0319554.1"
                     /translation="MKIENKNVRRNFFWGDGRFYTTDIVNKRAGVMIENVSKEEFTIT
                     LENGIRLSSNHFSAIVREEGDTRIQVSFVCPSIRLRLIFESRDDVLSKQLVLESSTEV
                     IKSVEVESFEFETEDNIFYPKRQDCIKEMANFSGYYVELGQPVYANSLFLGMEFPMSE
                     NKVDGRHYVSRYYFGTVVNQEKSLWSCIIGGACSYKKEEIQEAFFEYVEGIAQPSYFR
                     KQYNSWYDHMTDITEEGILKSFSEIRDGFENHGVHLDAYVVDDGWTNYQSVWEFNHKF
                     PNGLRNIKYLVNGFGSSLGLWIGPRGGYNGTEIIMSDWLEAHPELNIGSKNLISNDVN
                     VADFNYLNQMKKKMLEYQKEFDISYWKIDGWLLQPDKPDKSGPHGMYTMTAVYEFLIQ
                     LLIDLRKERGGKDCWLNLTSYVNPSPWFLQWVNSLWIQISQDVGFTENAGNDINRMIT
                     YRDIQYQEFLEKREIQLPMWSLYNHEPIYAVSANTWYMDHQMFASIPDFEAYLLFIST
                     RGNAFWEFHYSFDMFDEERWKANARAVKWIEENYQTLKYSKKIGGSPEKFEIYGYKCH
                     NQKTSTEILSLRNPAQIKQKIKIENLSIENFTRVIGDFTIQEDEIELAPYSIVILKK"
     gene            31727..33943
                     /locus_tag="VUZ44_000594"
     CDS             31727..33943
                     /locus_tag="VUZ44_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU0319555.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCAETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLGTEKILDLAKAAKDLEIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADKIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSRRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSGFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            33954..36971
                     /locus_tag="VUZ44_000595"
     CDS             33954..36971
                     /locus_tag="VUZ44_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEU0319556.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETV
                     RVTGNNLEKLITKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISDQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLPKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     NSYDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            36986..37714
                     /locus_tag="VUZ44_000596"
     CDS             36986..37714
                     /locus_tag="VUZ44_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEU0319557.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            37727..39493
                     /locus_tag="VUZ44_000597"
     CDS             37727..39493
                     /locus_tag="VUZ44_000597"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU0319558.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATLDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            39639..40790
                     /locus_tag="VUZ44_000598"
     CDS             39639..40790
                     /locus_tag="VUZ44_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU0319559.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            40935..41819
                     /locus_tag="VUZ44_000599"
     CDS             40935..41819
                     /locus_tag="VUZ44_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU0319560.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(41936..42013)
                     /locus_tag="VUZ44_000600"
                     /pseudo
     CDS             complement(41936..42013)
                     /locus_tag="VUZ44_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            42217..42468
                     /locus_tag="VUZ44_000601"
     CDS             42217..42468
                     /locus_tag="VUZ44_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU0319561.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEY"
     gene            42456..42749
                     /locus_tag="VUZ44_000602"
     CDS             42456..42749
                     /locus_tag="VUZ44_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319562.1"
                     /translation="MGVLGYYEGFVPYVSNQYKNQAEEEDKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQIS"
     gene            complement(42929..43056)
                     /locus_tag="VUZ44_000603"
                     /pseudo
     CDS             complement(42929..43056)
                     /locus_tag="VUZ44_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(43151..44482)
                     /locus_tag="VUZ44_000604"
     CDS             complement(43151..44482)
                     /locus_tag="VUZ44_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU0319563.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(44504..46015)
                     /locus_tag="VUZ44_000605"
     CDS             complement(44504..46015)
                     /locus_tag="VUZ44_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU0319564.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     IIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(46226..47173)
                     /gene="arcC"
                     /locus_tag="VUZ44_000606"
     CDS             complement(46226..47173)
                     /gene="arcC"
                     /locus_tag="VUZ44_000606"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU0319565.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVEADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(47338..48354)
                     /gene="argF"
                     /locus_tag="VUZ44_000607"
     CDS             complement(47338..48354)
                     /gene="argF"
                     /locus_tag="VUZ44_000607"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU0319566.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(48412..49641)
                     /gene="arcA"
                     /locus_tag="VUZ44_000608"
     CDS             complement(48412..49641)
                     /gene="arcA"
                     /locus_tag="VUZ44_000608"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU0319567.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            50397..52076
                     /locus_tag="VUZ44_000609"
     CDS             50397..52076
                     /locus_tag="VUZ44_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU0319568.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGE
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIHWIGNERGH
                     AGDPLWQKMNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMIIEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(52116..54200)
                     /locus_tag="VUZ44_000610"
     CDS             complement(52116..54200)
                     /locus_tag="VUZ44_000610"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU0319569.1"
                     /translation="MKPLLETIDTRLGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNPLMLFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFQPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            54371..55651
                     /locus_tag="VUZ44_000611"
     CDS             54371..55651
                     /locus_tag="VUZ44_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU0319570.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            55742..58387
                     /locus_tag="VUZ44_000612"
     CDS             55742..58387
                     /locus_tag="VUZ44_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU0319571.1"
                     /translation="MENIVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVATFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSMDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            58471..59340
                     /locus_tag="VUZ44_000613"
     CDS             58471..59340
                     /locus_tag="VUZ44_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU0319572.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALISYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            59334..61214
                     /locus_tag="VUZ44_000614"
     CDS             59334..61214
                     /locus_tag="VUZ44_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU0319573.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQSYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLIAIEANKACRANDIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSSINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            61366..61575
                     /locus_tag="VUZ44_000615"
     CDS             61366..61575
                     /locus_tag="VUZ44_000615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319574.1"
                     /translation="MKQKNYLVSNATVIQTYDKIAESECFLRAIGGIMLHLKLVKQEI
                     EAEKPASVEAWIISVKFKKGCYRHI"
     gene            61576..61938
                     /locus_tag="VUZ44_000616"
     CDS             61576..61938
                     /locus_tag="VUZ44_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319575.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(61990..>62339)
                     /locus_tag="VUZ44_000617"
     CDS             complement(61990..>62339)
                     /locus_tag="VUZ44_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0319576.1"
                     /translation="SLDIAVNYCHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYSQA
                     QTPRKSSKLKPLTVEDKTYNHALSKERSKVENIFAKVKTFKMISTTYRNHRKRFGLRM
                     NLIAGIINHELGF"
BASE COUNT        18999 a        11285 c        13534 g        18521 t
ORIGIN      
        1 aatagcaagc cacaagcaga tgataagaag ccatcaacta caaataattt aagcaaggac
       61 aagcaacctt ctaaccaagc ttcaacaaac gaaaaagcaa caaataaacc gaagaagtca
      121 ttgccatcaa ctggatctat ttcaaatcta gcacttgaaa ttgcaggtct tcttaccttg
      181 gcgggggcaa ccattcttgc taagaaaaga atgaaatagt gattgattca ttcaaaaatg
      241 tttgtaaaaa gtattcggct taaaagaaaa gagtctggga taaaaagatt ttgattttag
      301 gaattcttta ttataaattt ttaaaatcga tagattagac aaaaaagcga acaagacaga
      361 attctgagtg tcagataact gattttgttc gctttttata tttaatatta tacttttgtc
      421 ctaggctctt ttttgcatta tactttttcc aattgcaaga gggcttcaat ctctgccagg
      481 gtgctagctt gcgaaatggc tccacggagt ttggcagcgc cagatgttcc ccggagatag
      541 tgaggagcga ggccgcggaa ttcacgaact gcgacgtttt ctcctttgag gttaatcaat
      601 cgtttcaagt gttcgtaggc gatcttcatc ttgtcttcaa aggtcaaatc aggtaggatt
      661 tctcctgttt caaagtaatg gttgatttgg ttgaagaggt aaggatttcc catggcagct
      721 cggccaatca tgactgcgtc agcaccaact tcttcgatgc gttgcttggc ttcttggaca
      781 gtacggatat caccgttggc gatgaatgga atcttggtta gagcttgggc aaccttgtaa
      841 agggtctcaa ggtctgcgtg gccagtatac atttgttcac gggtacggcc atgcatggcg
      901 agggcagaaa cacctgcagc ctcagcagcg agggcatttt ctactgcaag agatgggtcc
      961 gcccagccgg tacgcatttt gacagtaagt gggatatcaa ggacagactg gaccttgttg
     1021 atgatagagt agatcttgtc aggatccttg agccacatag ctccagcttc gttcttcacg
     1081 attttgttga cagggcagcc catgttgata tcgacgatat cggtcttggt gttttcttgg
     1141 atgaattctg ctgcgcgtgc taggctgtct tcatcgctac caaaaagttg gatagagaca
     1201 gggttttcgc cctcatcgat atgaagcatg tgcagggttt tttcgttgtt gtattggatt
     1261 cccttgtcag agaccatttc cattacaacg agtccagctc cgagctcttt tgcgatggta
     1321 cgaaaggctg agttggtcac gccagccata ggcgctaaaa cggtacgatt gggaatctca
     1381 acattgccaa tcataaaagg tgtattaaga tttgtcacga atgagttcct ccaggtcctt
     1441 ttcatcaaag ttgtaagtag tttggcagaa ttgacaagtg atttctaccc cgtggtcttc
     1501 ctctttcatt tcctgtaagt ctgagcttgg aaggctggca agagcgttca taaagcgttc
     1561 atggctacag tcacattgga aacggatttc ttcttcagaa agacgcttgt aggcttcgtc
     1621 cccgtagata gccttgagga gggtttcgat atggtcgtcg ctttcgagaa gagtagagat
     1681 agctggcatt tcttggatgc gtttttcaaa gcgagcaatc tcttctttct tggctcctgg
     1741 caagacttga actaggaaac cacctgcaat cttgaccttg tcttcctcgt ccaaaaggac
     1801 attgaggccg accgctgaag gcgtttgttg gctttcagta aggtaaaagg caaggtcttc
     1861 accgatttct ccagagatga ggggagttat agagttgtaa ggatttccag taccgtagtc
     1921 tgtgataacg aggaattgac catttccaac aaaaggtccg actaggactt caccagtcgc
     1981 agtctttttg atgtcaacac caggattttg aacgtagcct ttgacgttcc ccttggtatc
     2041 agcgacggtg ataatagcac ctagagagct agatcccaac accttaactg taagtttggt
     2101 atttcctttt tcattggctg cgagaatctg gctggcgata agagttcgac caagcgctac
     2161 agttgagcta gcttgggttt gatgtttttc ttgagcagtg cggacggttt cagtgctatc
     2221 aaggacaaaa gcacgaaagg ctccgctttc tgatatagtt ttaataattt tatccatagc
     2281 tactatttta gcataaaaat gcccaaaggg ggagccgtgt gtttactgat tttcaggata
     2341 atggaccagg aaatcagcat gaaaataaaa agagaaacag attatttcag catttgtaag
     2401 atttatgcta tgcttaaggt agaaaatgaa aggggtaaca aatgtattta ggagatttga
     2461 tggagaaagc cgagtgtggt caattttcaa tcctttcctt tctattacaa gagtctcaga
     2521 cgaccgtcaa ggctgtaatg gaagaaacag gattttcaaa agcaacccta accaaatatg
     2581 tcaccctgct caatgacaag gctttggata gtggcttaga actgactatt cactcagaag
     2641 atgaaaatct gcgtctgtct atcggtgcag ctaccaaggg gagagatatt cggagcttgt
     2701 ttttggagag tgctgttaaa taccagattt tggtttatct tttctaccac caacagtttt
     2761 tagcccatca gctggctcaa gaattggtga ttagcgaggc tacgcttggt cgtcacttgg
     2821 ctggtttaaa tcagattttg tcagaatttg atttatccat ccaaaatgga cgttggcgag
     2881 gtccagagca tcagattcgc tatttctatt tctgtctttt ccgaaaggtc tggtcgagtc
     2941 aggaatggga aggtcacatg cagaaaccag agagaaaaca ggagattgcc aatttagagg
     3001 aaatctgcgg tgcaagtttg tctgtggggc agaaattgga cttggttctc tgggctcaca
     3061 tcagtcaaca acgtcttcgg gtcaatgctt gtcagtttca agtcatagaa gagaaaatgc
     3121 gagggtattt tgacaatatc ttctatcttc gtttgctgag aaaggttccg tccttttttg
     3181 ctgggcaaca tattccacta ggagttgagg atggtgagat gatgatattc ttctcttttc
     3241 tcctatctca tcgcattctt cctcttcata ctatggagta tattcttggt tttggagggc
     3301 agttggcaga tttactgacg caattgattc aagaaatgaa gaaggaggaa ctattggggg
     3361 attatacaga ggaccatgtc acctatgaac tcagtcagct ttgtgctcaa gtctatctct
     3421 ataagggcta tattttacag gatcgctaca agtaccagtt agagaatcgt catccatatt
     3481 tactgatgga acatgatttt aaagagacag cagaggagat ttttcatgct ctacctgctt
     3541 ttcaacaggg gacagattta gataagaaga ttctctggga atggctccag ttaatcgaat
     3601 atatggctga aaacggtggt cagcatatgc ggattggtct ggatttgaca tctggttttc
     3661 ttgtcttttc aaggatggca gccattttga aacggtattt ggaatacaat cgttttatta
     3721 ccattgaagc ttatgaccct agtcggcatt atgatttgct ggttaccaat aacccgattc
     3781 ataagaagga acagacacca gtctattatt taaaaaatga cttggatatg gaggatttgg
     3841 tagcgattcg ccagttatta ttcacttaaa aggcttggtt aatccaggtc ttttttgtga
     3901 aattcacaca atctcctcac atttttttaa aaattaaaaa aagttgataa acaagaaagc
     3961 gctttatttt gtatactagt aagtgtaaag aggaaacacc tcaagatctt tatcaggagg
     4021 acagtacatg tcacaagaaa aatacatcat ggccattgac cagggaacta caagttctcg
     4081 tgccatcatt ttcaacaaaa aaggggaaaa ggttagctcg agtcaaaaag agtttaccca
     4141 gattttccct caagcaggtt gggttgagca caatgccaat gaaatttgga actctgttca
     4201 gtcagttatt gcgggtgctt tcatcgaaag tggtgtcaag ccaaatcaaa tcgaggcaat
     4261 cgggattacc aaccaacgtg aaacaacggt tgtctgggat aagaaaacag gacttcctat
     4321 ctacaatgct atcgtttggc agtcacgcca gacagcacct ttggctgagc aactaaaaag
     4381 ccaaggttat gtggaaaaat tccatgaaaa gactggtttg attattgatg cttacttctc
     4441 tgctaccaag gttcgttgga ttttggatca tgtagaaggt gctcaagagc gagcagaaaa
     4501 aggggaattg ctctttggta ctatcgatac ttggttggtt tggaaattga ctgacggtgc
     4561 ggctcacgtg actgactact caaatgcagc tcgtaccatg ctttataaca ttaaagaact
     4621 caaatgggat gatgagattt tggaaatcct taacattccg aaggctatac ttccagaagt
     4681 tcgttctaac tccgaaatct acggcaagac agctccattc catttctacg gtggagaggt
     4741 gccaatctca ggtatggctg gggaccaaca agcagccctc tttggacagt tggcttttga
     4801 gccaggtatg gttaagaata cttatggaac aggctctttc atcatcatga atactgggga
     4861 agagatgcag ttgtctgaaa acaacctctt gacaaccatt ggttacggaa tcaacggtaa
     4921 ggtttattat gccttggaag gttctatctt catcgcagga agtgctattc agtggcttcg
     4981 tgacggtctt cgcatggttg aaaattcacc agaatctgaa aaatacgctc gtgattctca
     5041 caacaacgat gaagtttatg tcgttccagc ctttacaggt ctaggcgctc catactggaa
     5101 ccaaaatgct cgtggttccg tctttggttt gactcgtgga acaagcaaag aagactttat
     5161 caaggcgact ttgcaatcta ttgcttatca agtgcgtgat atcatcgaca ccatgcaagt
     5221 ggatactcag accgccattc aagtactgaa ggtggatggt ggtgcagcca tgaacaactt
     5281 cctcatgcag ttccaggcgg atattttagg cattgacatt gcacgtgcta aaaacctgga
     5341 aacaacagct ctaggagcgg ccttcctagc aggtttgtca gtagggtact ggaaagactt
     5401 ggacgagttg aaactcttga acgagacagg agaactcttt gagccatcta tgaacgaatc
     5461 tcgcaaggaa caactctaca agggctggaa gaaggctgtg aaagcaactc aagtctttgc
     5521 ggaagtagac gactaatact ggcagaataa agcgatttat ttagaaagtg tgtaaatatg
     5581 gaattttcaa agaaaacacg tgaattgtca attaaaaaaa tgcaggaacg taccctggac
     5641 ctcttgatta tcggtggagg aatcacagga gctggtgtag ccttgcaggc ggcagctagc
     5701 ggtcttgaga ctggtttgat tgaaatgcaa gactttgcag aaggaacatc tagtcgttca
     5761 acaaaattgg ttcacggagg acttcgttac ctcaaacaat tcgacgtaga agtggtctca
     5821 gatacggttt ctgaacgtgc agtggttcaa caaatcgctc cacacattcc aaaatcagat
     5881 ccaatgctct taccagttta cgatgaagat ggagcaacct ttagcctctt ccgtcttaaa
     5941 gtagccatgg acttgtacga cctcttggca ggtgttagca acacaccaac tgcgaacaag
     6001 gttttgagca aggatcaagt cttggaacgc cagccaaact tgaagaagga aggcttggta
     6061 ggaggtggag tgtatcttga cttccgtaac aacgatgcgc gtctcgtgat tgaaaacatc
     6121 aaacgtgcca accaagacgg tgccctcatt gccaaccacg tgaaggcaga aggcttcctt
     6181 tttgacgaaa gtggcaagat tacaggtgtt gtagctcgtg atctcttgac agaccaagta
     6241 tttgaaatca aggcccgtct ggttattaat acaacaggtc cttggagtga taaagtacgt
     6301 aatttgtcta ataagggaac gcaattctca caaatgcgcc caactaaggg agttcacttg
     6361 gtagtggatt caagcaaaat caaggtttca cagccagttt actttgacac aggtttgggt
     6421 gacggtcgta tggtctttgt tctcccacgt gaaaacaaga cttactttgg tacaactgat
     6481 acagactaca caggtgattt ggagcatcca aaagtaactc aagaagatgt agattatcta
     6541 cttggcattg tcaacaaccg ctttccagaa tccaacatca ccattgatga tatcgaaagc
     6601 agctgggcag gtcttcgtcc attgattgca gggaacagtg cctctgacta taatggtgga
     6661 aataacggta ccatcagtga tgaaagcttt gacaacttga ttgcgactgt tgaatcttat
     6721 ctctccaaag aaaaaacacg tgaagatgtt gagtctgctg tcagcaagct tgaaagtagc
     6781 acatctgaga aatatttgga tccatctgca gtttctcgtg ggtctagctt ggaccgtgat
     6841 gacaatggtc ttttgactct tgctggcggt aaaatcacag actaccgtaa gatggctgaa
     6901 ggagctatgg agcgcgtggt tgacatcctc aaagcagaat ttgaccgtag ctttaaatta
     6961 atcaattcta aaacttaccc tgtttcaggt ggagaattga acccagcaaa tgtggattca
     7021 gaaatcgaag cctttgcgca acttggagta tcacgtggtt tggatagcaa ggaagctcac
     7081 tatctggcaa atctttacgg ttcaaatgca ccgaaagtct ttgcacttgc tcacagcttg
     7141 gaacaagcgc caggactcag cttggcagat accttgtccc ttcactatgc aatgcgcaac
     7201 gagttggctc ttagcccagt tgacttcctt cttcgtcgta ccaaccatat gctctttatg
     7261 cgtgatagct tggatagcat cgttgagcca gttttggatg aaatgggacg attctatgac
     7321 tggacagaag aagaaaaagc aacttaccgt gctgatgtcg aagcagctct cgctaacaac
     7381 gatttagcag aattaaaaaa ttaagaaaaa ataaaagagg tggagggcag cattccttgt
     7441 cgcccgtccc ttctttttaa tggagacaga aagatgatga atgaattatt tggagaattt
     7501 ctagggactt taatcctgat tcttctagga aatggtgttg ttgcaggtgt ggttcttcct
     7561 aaaaccaaga gcaatagctc aggttggatt gtgattacta tgggttgggg gattgcagtt
     7621 gcggttgcag tctttgtatc tggcaagctc agtccagctc atttaaatcc agctgtgaca
     7681 gttggtgtag ctttaaaagg tgacttgcct tgggcttccg ttttgcctta tatcttagcc
     7741 cagttcgcag gggccatgct gggtcagatt ttggtttggt tgcaattcaa acctcactat
     7801 gaggcagaag aaaatgcagg caatatcctg gcaaccttca gtactggacc agccatcaag
     7861 gatactgtat caaacttgat tagcgaaatc cttggaacct ttgttttggt gttgacaatc
     7921 tttgctttgg gtctttacga ttttcaggca ggtatcggaa cctttgcagt gggaactttg
     7981 attgtcggta tcggtctatc actaggtggg acaacaggtt atgccttgaa cccagctcgt
     8041 gaccttggac ctcgtatcat gcacagcatc ttgccaattc caaacaaggg agacggagac
     8101 tggtcttacg cttggattcc tgttgtaggc cctgttatcg gagcagcctt ggcagtgctt
     8161 gtattctcac ttttctagtt tatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg
     8221 ccttaccgta ctcaagtaca gcttgcggct agcttcctag tttgctcttt gattttcatt
     8281 gagtattaga aaacaattat tttgatagag cttgggcaag agcccaattt cagcaaaaaa
     8341 tgaagtaaat cttctcataa taaaacgcat catatcaagc acgaaaattc cacgaggtca
     8401 actacagtca gaaagctgaa caacaagcca aaacgcccaa aaaaggcggc aaaaagcaag
     8461 cacctgcaag caacgtgccg aaatggtcaa atcctgatta tgtcaacgaa ttagacccaa
     8521 aaatcgttga tatgctagta gaatttcaca agtcacaagg cactttggaa actcccgagg
     8581 cgcaagcaga aatcgcccaa aaacgtgaag aaatcgagca aaggagagct gagcttgagg
     8641 ataaaaaaca agagcttttg aaccgcttga acaaatagag tttcgcaagt attatgctta
     8701 caaattactt gagcaattaa ctaaaatata aaccctgcct agatataaag gcagggttta
     8761 tattttagaa attcacgtag gttgttacgg tttttacata cccagtatag tttgagtttc
     8821 tatagtattc agtgataaac ttccattttc tttgagcaac atggatataa gtacttgtta
     8881 tgtagtatgg atatgggctt tgtgaatcca agtaagactg ataagcttgt ataccaaaat
     8941 atgctccacc aattattgca ccccatggac cccccaataa agcacctatc ctaccaatca
     9001 tataactgat tccagcacca gtcatgaagt tagcgaatgt gttagcttgt ttattcccat
     9061 gtattgtgtt gacgtaattc caaacattag gatcgtatga tctaaaagat atatttaggt
     9121 cgatttcatt cttttgataa gccatataaa atgccccatt gatatagacg ccgtcagcac
     9181 gtcgttcaat agtgtctaca cttccatctg gattgacaac ctcaagaact tcatcgctta
     9241 aaatatttac ttgcgtatct ccgaaccgca ctgatgagcc attctcaaac tgagcctcac
     9301 cagatacaac tttagagttt gccgataagc tatcatcagc aaaaacaaca agcgacgggg
     9361 aaatgctaga catacagaaa acagacataa ctagcaaaca catgcattta aacatcttag
     9421 acataacgga aactcttttg tatttttgat ttttttcaac ttttattata caataaaacc
     9481 aaataaaaag aaagcggtaa caatatgctt aatgcgaaaa ttttttatat atttttatgt
     9541 ttgatcgtta tcgaaactac aggcttgttg ttgttgaaaa gaggtctcga aatgggttat
     9601 ttagacacag aagctattat cctcgcagtt ttttcatttg ctttttacaa cctatgttca
     9661 ttcgcttggg tctgctctac aataaaaaac aataaaaaat aaatagacgt attttcaaaa
     9721 aaaaaaatgc atatttatat tagcaaaatg acgatttaaa tcgtcgtttt tttgtagtac
     9781 gacgggcatg tcgtatatct gaggtgtaag tcctcggtgg gcacctgcta ccggtgaacc
     9841 caatagcgat tcccaagcct gactatcgtg aggtagcgga ttaaaacggt ctggggatag
     9901 accgttttaa gtctgacgca ggaaataaga atcgtcagag gaagggatag cgaaatcgtg
     9961 gctctacgaa caggaacgtg atagtaaggc gtatatagcg gataaggagg cttcaaactc
    10021 taaagtccaa aaaggtagtc gtaacctata tgtgtaaatc acgagagtaa ttgaattcgg
    10081 actaaggttt gtgtgaaaaa gataaatctt tctagagtct aaagactctg cgtcagattt
    10141 cctattttca ctgtaacctt ttaacgtcct catatcttgt ataaacgagg aaagatgtac
    10201 gacttatccc gtgaggtttc atgagcgctg aaagcgtagt aacaacgaat catgagaagt
    10261 cagccgagcc catagtagtg aggaaacttc tgtagtggaa gtggagcgaa ggggtgaata
    10321 ctcaaacagt ctggggagag actgtttgag gtctgtcgct agaaagagaa aacgacagat
    10381 cgaagtaatc ctacttcact tgtgtctgta aaatgagtgg tctgatagaa ctggactttg
    10441 acacgtaatg actagatgaa ggttcaccaa tataagatgt ccctcaggca ccaaaacaag
    10501 aaaggaatac gcacatgtca aaactgctag ataagatatt atcacgcgaa aatatgctgg
    10561 aagcctacaa tcaagtaaaa tccaataaag gctcagctgg gattgatgga atgactatcg
    10621 aagagatgga taattatctc agacaaaact ggcgcttgac taaggaactg ataaaacaga
    10681 gaaaatataa gcctcaacca attcttaaag ttgagatacc taaaccagac ggaggcatcc
    10741 gtcaactagg aatttcaaca gttatggata gaatgattca acaggccatt gtccaagtca
    10801 tgagccccat ttgtgaaccc catttctcag atacgagtta tggtttcaga ccaaataggt
    10861 catgtgaaaa agccatcatg aagctcttag aatacttaaa tgacggctat gagtagatag
    10921 tggatataga cctagagaaa tttttcgata cagttcctca agatagattg atgtccttag
    10981 tacataacat tatcgaagac ggagatacgg aatccttgat tcgtaagtat cttcattcag
    11041 gtgttatcat taatggtcaa cgttataaaa cactagttgg tacaccacag ggaggaaatt
    11101 tatctcctct cttatccaat atcatgctta atgaattgga caaggaatta gaaaagaggg
    11161 gacttcgatt tgtgcgctac gcagatgatt gtgtgatacg gtcggaagcg aggcagccgc
    11221 taagcgtgtg atgtattcag tcagtcgttt tattgagaaa cggctaggtt tgaaagtaaa
    11281 catgaccaag actaagatta ccagaccaag agagttgaaa tatctaggtt ttgggttctg
    11341 gaaatcatca gatggttgga aaagccgtcc acatcaagat agtgttcgga gatttaagtt
    11401 taaattgaag aaactaacac agaggaaatg gagtatagac ctaacaagac gtattgagca
    11461 actgaatttg tctattcgag gatggataaa ctatttctca ttgggaaata tgaaaagtat
    11521 agtcgccagc atagatgagc gcttgcgtac tcgcctacga gtgattatct ggaagcaatg
    11581 gaagaagaaa tcgagacgat tatggggatt gcttaagtta ggagttccta aatggatagc
    11641 agataaggta tctggctggg gcgaccatta tcaattagta gctcagaagt cggtacttaa
    11701 acgtgctata tcaaaaccag tccttgaaaa acgtggactg gtttcgtgtt tggattatta
    11761 ccttgaacga catgcgttaa aagttagttg aaccgccgta tgccgaacgg cacgtacggt
    11821 ggtgtgagag gggctagaga ttatccccta ctcgattaac tcccctgaaa tttattttaa
    11881 ttatgcaaat ttcacgtatt tttgatgctg agacgacgat cctgggaact tttcagatat
    11941 ttttttgact atctaaatct atcattagaa aagcttagag cgccaaagga tttgagcgtt
    12001 tttctgattt ttaagacttt ttcccagtct ctttttcgat tgaagatgta attattctac
    12061 taactaacta acttcttagt actagccaac aacgataatc ataattcctc ctaaaattag
    12121 gaataataaa ggcaatagtt tttgtttttt catgtaaaaa acctcacttt tgttttctgc
    12181 tattttatgc taaaatatta aaaatcaaat ttaattccaa agtttgtaac taaaggggga
    12241 gcgctacatg tctaattcat ttgtcaagtt gttagtctct caattatttg caaatttagc
    12301 agatattttc tttagagtaa caatcattgc taacatatac attatttcaa aatcagtaat
    12361 tgccacatca ctagttccta tcttaatagg aatatcctct tttgttgcga gtcttttagt
    12421 tccgttggtt actaaaaggt tagcgctaaa tagggtttta tctttatctc aatttggaaa
    12481 gactatatta ttggcgatac tggtaggaat gtttaccgta atgcaatccg tagcgccttt
    12541 ggtgacctat ctatttgttg ttgcaatttc catactagat ggttttgcag cacccgtttc
    12601 ctatgctatt gtgccacgct atgcgaccga tttgggtaag gctaattcag ccttatcaat
    12661 gactggtgaa gctgttcaat tgataggttg gggattaggt ggactcttgt ttgcaacaat
    12721 tggtctgtta cctaccacgt ttatcatttt agtcttgtat atcatttcta gctttctgat
    12781 gttatttctt cctaacgctg aagtggaggt gttagagtca gaaactaatc ttgaaatttt
    12841 gctcaaaggt tggaagttag ttgctagaaa tcctagatta agactttttg tatcagcaaa
    12901 tttattggaa attttttcaa atacgatttg ggtttcttcc attatacttg tttttgtaac
    12961 ggagttatta aataaaacgg aaagttactg gggatattct aatacagcat actctattgg
    13021 tattataatt agtggcttaa ttgcttttag gctatctgaa aagttccttg ctgctaaatg
    13081 ggaaagtatt ctttttcctc ttgtagctat ggcaatagtg acactgacta ttctatattt
    13141 tccaaacgca cagatgtttt tattattttc agctttagtt ggtatgttat cgcaactaaa
    13201 agaagttcct gaaagtgtat ttcttcagga aacagtagag gaaaatcatt tagttaatgt
    13261 ctattccgtt cttgaagtga tttctacatt agcattttca gtatttgttt tgctaatgag
    13321 ctatattact gagagttttg gtattagcat cagtttttgg ctatcagcca tttgtctgat
    13381 gatagaagct attttaattt atatcagacg agattatttt aaatgagaga gtggttaaaa
    13441 agtctttaaa aatcagaaaa gcgcatagta tcaggtgttg aaaaaacttg atattgtgtg
    13501 ttttattatg ggaagattta cttcattgtc tcctgaaatg gagttttgaa gcaggatcac
    13561 tctatttgaa aatatacata gaaaaaccgc ataatcctta aaataagctg aaatctattg
    13621 gaaacatacg gtaaacaatt gaaaagatac tatataaagt ggtacaatgg tagaaaaata
    13681 agctagtaag aatcactctt attttagcga aaaattacag aaatgaatgg tttttcttga
    13741 tgaaacagag aaaagaattg tacctctttc ttggtcggac agccttgtat tttcttatct
    13801 ttctagggct gctttacttc tttagctatc ttggtcaggg tcaaggaagc tttatctata
    13861 atgaatttta acttgaagga gaatccctat tgtgtcaaat aaaccaatag cagatatgat
    13921 tgaaaccatt gagcattttg ctcagacaca gcctagctat cctgtctata atgttttggg
    13981 gcaggaacac acttatggcg atttaaaggc tgattcggat agtttggctg cagtcattga
    14041 ccaactaggc ttgcctgaga agtctcctgt ggttgttttt ggtggccaag aatatgaaat
    14101 gttggcaacc tttgtagcgc tgactaagtc aggtcatgcc tacattccaa ttgatagcca
    14161 ttcggccttg gagcgagttt cagctatttt agaagtagca gagccaagct tgattattgc
    14221 catttcagcc tttcccttgg agcaggtttc tacaccaatg ataaatctag ctcaggttca
    14281 agaagccttt gcccaaggga acaactatga aatcacgcat ccagtcaagg gagatgataa
    14341 ttactacatt atctttactt ctggtacgac tggtaagcct aagggagtgc agatttcaca
    14401 tgataatctc ctcagcttta caaactggat gattacggat aaggaatttg cgacaccgag
    14461 tcgtccgcaa atgctggcac agccacctta ttcttttgac ttgtctgtca tgtattgggc
    14521 accgaccttg gcacttggtg gtacgctttt cactcttcct tcagtcatca ctcaggactt
    14581 taagcaactc tttgcggcta tcttttcatt gccaatcgct atctggacat caacaccatc
    14641 ctttgcagat atggccatgt tgtctgaata cttcaacagt gagaaaatgc ctggaatcac
    14701 gcatttctac tttgatggtg aagaattgac ggtcaaaaca gctcaaaaac tgcgcgagcg
    14761 tttcccaaat gcccgtatca tcaatgctta cggcccaaca gaagcgacag tagctctgtc
    14821 agcagttgcc gtgacagacg agatgttagc gactctcaaa cgcctaccaa tcggctatac
    14881 taaggctgat tctccaacct ttatcattga cgaggaagga aataaactgc caaatggtga
    14941 gcagggagaa atcattgttt ctgggccagc tgtttcaaaa ggttatatga acaatcctga
    15001 aaaaacagca gaagccttct ttgagtttga aggtctgcca gcctatcaca caggcgatgt
    15061 gggaaccatg acagatgagg gcttgcttct ctacggcgga cgcatggact tccagattaa
    15121 gtttaacggt taccgcattg agttagaaga tgtctctcaa aacctcaaca agtctcgctt
    15181 tatcgaatct gctgtcgcag taccgcgcta taacaaggac cacaaggtac aaaatctatt
    15241 ggcttatgtc atcttaaaag acggtgttcg tgagcagttt gagcgagata tcgatattac
    15301 caaggccatc aaggaagacc tgacagacat catgatgtcc tatatgatgc catctaaatt
    15361 cctttaccga gacagtttgc cactaactcc aaatggaaag attgacatca aaggattgat
    15421 taacgaggtg aataagagat gatggagttt tttcaacagc ttcctcattt agagccatat
    15481 ggcaatcctc agtattttgt ttatgtgatt gctgcaacct tgcccatctt tataggtctc
    15541 tttttcaaga aacgctttgc ctggtatgaa gtgttggtaa gtctcttctt tattgtcacc
    15601 atgttggtgg gtggaaagac caatcaacta gctgccttgg gtatttacct ttgctgggaa
    15661 atattgctcc tgcttttcta caagcattat cgaaaaagca aggatggcaa gtgggtcttc
    15721 tacttagtta gttttctgtc cctacttccg attatctttg tcaaggtgca accagctatc
    15781 aatggaacgc agtctttgct tgggttcttg ggaatttctt accttacctt tcgttcggtt
    15841 ggaattgtca tcgagctgag agatggagtg attaaggatt ttaccctctg ggaattcctc
    15901 cgtttccttc tcttcatgcc aactttctcg agtggtccaa tcgatcgctt taagcgattt
    15961 aatgaaaatt atcaggctat tcctgagcga gatgagttga tggatatgct ggatgaatct
    16021 gtccgctata tcatgtgggg ctttttgtat aagtttatcc tagctcatgt tttaggagag
    16081 accttactac ctcctctgaa gaatttagcc ttgcagtcag gtggcttctt taatctctat
    16141 gccttggcag ttatgtatac ttttggtctg gaactcttct ttgactttgc aggttattct
    16201 atgtttgctt tggccatctc aaacttgatg ggaatccgta gccctatcaa ctttaacaag
    16261 ccctttttat caagggattt aaaggagttt tggaatcgct ggcatatgag tctgtccttc
    16321 tggttccgtg actttgtctt tatgcgaatg gtgatggtgt taaccagaaa gaaagtcttt
    16381 aaaaatcgta atgtaacctc aagcatggcc tacattgtaa atatgctgat tatgggattt
    16441 tggcatggcg tgacctggta ctatatcgcc tatggactct ttcatggact aggcttggtc
    16501 atcaatgatg cctgggttcg caagaaaaaa acgctcaata aggaacggaa aaaagcaggg
    16561 aaggctgccc tacctgagaa tcgctggatt cagtttcttg gcatggttgt cactttccat
    16621 gttgtcatgt tgtcattctt aatcttttct ggattcttga ataatctatg gtttaaaaaa
    16681 taaaaggaaa taaaatatgg atatcaaatc agaagttatt gaaattattg atgagttgtt
    16741 tatggaagat gtttctgaca tgatggatga agatcttttt gatgcaggtg tcttggatag
    16801 tatgggaacg gttgagttga ttgtggagat tgagaaccgt tttgacattc gtgtccctgt
    16861 aacagagttt ggtcgtgacg actggaatac agctaataaa atcatagctg gtattgtgga
    16921 gctacaaaat gcttaaacgc ttatggatga tcttcggacc ggtcttgatc gctggtttgt
    16981 tggtttttct gctcattttc ttttatccta ctgagatgca tcataatcta ggagctgaaa
    17041 agcgttcagc agtggctact actatcgata gttttaagga gcgaagtcaa aaagtcagag
    17101 cactatctga tccaaatgtg cgttttgttc ccttctttgg ctctagtgaa tggcttcgtt
    17161 ttgacggtgc tcatcctgcg gtattagctg agaaatacaa tcgttcctac cgtccttatc
    17221 ttttaggaca ggggggagct gcatcgctta accaatattt tggaatgcaa cagatgttac
    17281 cacagctgga gaataaacaa gttgtgtatg ttatctcacc tcagtggttc agtaaaaatg
    17341 gctatgatcc agcagccttc cagcagtatt ttaatggaga ccagttgact agttttctga
    17401 aacatcaatc tggggatcag gctagtcaat atgcagcgac tcgcttactg caacagttcc
    17461 caaacgtagc tatgaaggac ctggttcaga agttggcaag taaagaagaa ttgtcgacag
    17521 cagacaatga aatgattgaa ttattggctc gttttaatga acgccaagcc tccttttttg
    17581 gtcagttttc ggttagaggc tatgttaact acgataagca tgtagctaag tatttaaaaa
    17641 tcttgccaga ccagttttct tatcaagcaa tagaagatgt tgtcaaagca gatgctgaaa
    17701 aaaatacttc caataatgag atgggaatgg aaaattattt ctataatgag cagatcaaga
    17761 aggatttgaa gaaattaaag gattctcaga aaagctttac ctatctcaag tcgccagagt
    17821 ataatgactt gcagttggtt ttaacacagt tttctaaatc taaggtaaac ccgattttta
    17881 tcattccacc tgttaataaa aaatggatgg actatgctgg tctacgagag gatatgtacc
    17941 aacaaacggt gcagaagatt cgctaccagt tagaaagtca aggttttacc aatatagcag
    18001 atttttctaa ggacggcggg gagcctttct ttatgaagga caccattcac cttggttggt
    18061 tgggttggtt ggcttttgac aaggcagttg atcctttcct atccaatccc acaccagctc
    18121 cgacttacca tctgaatgag cgctttttca gcaaagattg ggcgacttat gatggagatg
    18181 tcaaagaatt tcaatagata atataatata gaagagttca agaatgaaac tagttttcac
    18241 gttttttctt gactcttttt ttgcttgtga tataattaac tggtaaacaa aatgtcaaag
    18301 aatagtattt ttctcttaaa aaagagaagt ctaaaaggaa aggagtcaga tatgagacag
    18361 ctagcaaagg atatcaatgc ttttttgaat gaggtgattt tgcaggcgga aaatcagcat
    18421 gaaatcctaa taggtcattg cactagcgag gtggccctga ccaatactca ggagcatatc
    18481 cttatgctct tgtcagagga atctttaaca aattcagaat tggcccgtcg tctcaatgtc
    18541 agtcaggcgg cagttaccaa ggccattaag tctttggtca aggaagggat gttggaaaca
    18601 tctaaagatt ctaaagatgc gcgtgtgatt ttttatcagt tgactgactt ggctcgtcca
    18661 atcgctgagg agcaccacca tcaccatgag catacacttt taacctatga acaagtggcg
    18721 actcagttta ctccaaatga acaaaaagtg attcagcggt ttttgactgc tttagtagga
    18781 gaaatcaaat aatgagatat attacggtag aggatttgtc cttctattat gataaggagc
    18841 ctgttcttga acatatcaat tatagtgttg atagtgggga atttgttacc ttgactgggg
    18901 aaaatggagc ggctaagacg acgctcatca aggctagtct tggaattctg caaccacgca
    18961 ttggaaaggt ggctatttca aagacaaata cgcaaggtaa gaaattgaga atagcctatc
    19021 ttcctcaaca aattgccagt tttaatgctg gttttccaag tacggtctat gaatttgtca
    19081 agtcgggtcg ctatccgaga aaaggctggt tccgtcgttt gaatgctcat gatgaggagc
    19141 atatcaaggc tagtctggac tcagttggca tgtgggaaca tcgagacaaa cgcttggggt
    19201 ctctatctgg gggacaaaag cagcgagcgg taattgcgcg tatgtttgct tctgaccctg
    19261 atgtgtttat cctagacgag ccgacaacgg ggatggatgc aggaagtaaa aatgaatttt
    19321 acgaactcat gcaccacagc gcccatcatc atggcaaggc tgttttgatg attacccatg
    19381 accctgaaga agttaaggat tatgcggatc gcaatattca tctagtccgt aaccaagact
    19441 cgccatggcg ttgtttcaat gttcatgaga atggccagga ggtgggccat gcttagttta
    19501 ttatcttacg actttataca gcgcgccttt ttggcggtta ttgctatgag tcttttctca
    19561 ccggtattgg gaaccttcct catcttgcgt cgtcagagtt tgatgagtga tacccttagc
    19621 cacgtctcac tttcaggtgt agcctttggt ctggttttgg ggatttctcc aactgtttct
    19681 actattgcca ttgtcttgat tgcggcggtc tttctggagt atctccgtac ggtttacaag
    19741 agctttatgg aaatcgggac agctatcctc atgtcaacag gtctggctgt ttctctgatt
    19801 gtcatgagca agggtaaaag ctcgagttca atgagtttgg accaatatct ctttggttcg
    19861 atcgtgacta tcagtgaaga acaggtcatt tccctctttg ttattgcggc ggttgttttg
    19921 attttgacct ttctctttct tcgtcctatg tatatcttaa cttttgacga agatacggcc
    19981 tttgtggatg gcttgccagt tcgtaccatg tccattcttt ttaacatggt gacaggggtg
    20041 gctattgccc ttatgattcc tgcagcagga gctcttctgg tatcgaccat tatggtcttg
    20101 ccagctagta ttgccctgcg tctggggaaa aactttaaat cggttatgct gcttgccagt
    20161 gcgattggct ttttgggaat ggtagcagga ctttacattt cctactatgc agaaacacct
    20221 gcaagtgcaa gtattaccat tatttttgta actgtcttta tactaatcag tttagtaaga
    20281 cgttttatca aataggagac gaacgtgaaa aaaattagct tattactagc cagtctatgt
    20341 gccttgtttt tagtggcttg ttccaatcaa aaacaggcag atggtaaact caatatcgtg
    20401 acaacctttt accctgtcta tgaatttacc aagcaagttg caggagatac ggctaatgta
    20461 gaactcctaa tcggtgctgg gacagaacct catgaatacg aaccatctgc caaggcagtt
    20521 gccaaaatcc aagatgcaga taccttcgtt tatgaaaatg aaaacatgga aacatgggta
    20581 cctaaattgc tagatacctt ggataagaaa aaagtgaaaa ccatcaaggc gacaggcgat
    20641 atgttgctct tgccaggtgg cgaggaagaa gagggagacc atgaccatgg agaagaaggt
    20701 catcaccatg agtttgaccc ccatgtttgg ttatcaccag ttcgtgccat taaactagta
    20761 gagcacatcc gcgacagctt gtcagcagat tatcctgata aaaaagagac ctttgagaag
    20821 aatgcagctg cctatatcga aaaattgcaa tccttggata aggcttacgc agaaggcttg
    20881 tctcaagcaa aacaaaagag ctttgtgact caacacgcag cctttaacta tcttgccttg
    20941 gactatggac tcaaacaagt cgcaatctca ggcctttctc cagatgcaga gccatcagct
    21001 gctcgcttgg cagaattgac agagtatgtc aagaaaaata aaatcgccta tatctatttt
    21061 gaagaaaatg cctcacaagc ccttgctaac acactttcaa aagaagcagg tgtcaaaact
    21121 gatgtcctca atcctttaga aagtctgaca gaagaggaca ccaaggctgg agaaaactac
    21181 atttccgtga tggagaaaaa cctcaaggct ttgaaacaaa caacagacca agaaggccca
    21241 gcaatcgaac ctgaaaaggc agaggatacc aagacagtcc aaaatggtta cttcgaggat
    21301 gcagctgtca aggaccgcac cttgagtgac tatgcaggta actggcaatc agtttatcct
    21361 ttccttgaag acggcacgtt tgaccaagtc tttgactaca aggctaagtt gactggtaag
    21421 atgacccagg ctgagtacaa ggcttactat acaaaaggct atcagacaga tgtgactaag
    21481 attaacatta ctgataatac tatggaattt gttcaaggtg gacaaagcaa gaaatacact
    21541 tacaagtatg tcggtaagaa agttttgact tacaagaaag gcaatcgtgg cgtgcgtttc
    21601 ctctttgaag ccacagatgc tgacgctgga caattcaagt atgttcagtt tagtgaccac
    21661 aatatcgccc cagttaaggc agaacatttc catatctttt ttggaggtac aagccaagaa
    21721 actctatttg aagaaatgga taattggcca acctactacc cagataacct atctggccaa
    21781 gaaatcgccc aagaaatgtt ggcgcattga tgagaaatcg actagttcat aagagctagt
    21841 cggttttttg atactagatg gctaacttca ttatagacct ttcagaacta agggaacctg
    21901 aaaaaataaa taaaactctt gaaatatctg ggcttatatg ctagaatgta gttagtgtat
    21961 aaggttcatt agaacaccaa agcccctaac tagtgccata gttaagggct tttttgacgt
    22021 atcttagcga tttaacgggt gtttataggc tagtcattcg gtctacttct taccatctag
    22081 ccatttgcag acgaaataca agataattcc agctataaca tctgctataa tagtaagagc
    22141 aagctctggt ataaggctca ttagtttcac ctcctctcac gaacccatag gaacgtaatc
    22201 ggtaaccgat gacaaaaata gtataccaca ctaaatttag atcatcaacc tcacttaata
    22261 cttgaactat tgtagattat atgctaaaat gtagttaatt gataaggttc attagaacac
    22321 caaagcccct aactatggcc gtagttaagg gcttttttga cgtatcttag cgatttaacg
    22381 ggtgtttata ggctagtcag tcggtctact ccttactatc tagccatctg cagacgaaat
    22441 acaagataat tccagctata acatccgcta taatagtaag agcgagctct atgataaggc
    22501 tcattagttt cacctcctct cacgaaccca taggaacgta atcggtaacc gatgacaaaa
    22561 atagtatacc acaatacatt tagatcatca aggtcactta attcttgaaa tatagggtct
    22621 aggcgacaaa gtctttaaaa tcagaaaaac gcataatatc aggtgtgcaa aaacttgata
    22681 ctatgcgttt tattgtggga aggtttactc cattttctcc tgaaattgag tttttgtcca
    22741 gcctctgttt ttagggttgc tgagaaaata atgtcatgtg gtgaatattt gtaaatcagt
    22801 cagcagacag aacgaatact cttcgaaaat ctcttcacat catgtcagct tcgtctttcc
    22861 gtatatatgt gactgacttc atcagttcta tctacaacct caaaacagtg tttcgagctg
    22921 acttcatcag ttttcaaatc tgtactttga gcaagctgag actagcttcc tatttgattt
    22981 tcattgaata tcagaaaccc attctccatc aaataattcg actgcgtcta ataatttttg
    23041 atctggcacg gtgtctgaaa taaaggttgt gtatttggag aggggattaa ttttaaaaaa
    23101 tccagtcttg taaaatttag aactatcaat cagtaagatg gtttcatggg ctttgtcaat
    23161 aatattcttt tttgaaatag cttggctgag agaagcttca taaacatatt ggtcatcaat
    23221 acctcttgct gaacaaaatg ctaaatcgat attaaaatga tctaataaag aattttcctt
    23281 atcatagttg accacggaac aggattgatg tttgacctcg ccagatgtga taaagatttt
    23341 ggagctatct ttaacagttt cagatagggt ttgtgcagta tgtaaaccat ttgtaaaaat
    23401 aatcaaatta tcaagttcag aaagataggg acagagttcg tagacagtcg tactggaatc
    23461 cagatagata cacataccag accgaataaa gtctttagcg agactagcga ttagtctttt
    23521 ttgcctagta ctttctcctt cacgtatttg atgagaaagt tcaattgtgt tcatagagga
    23581 cagggtcacg tatccgtgct ttcttttgat aagaccttga ttttctaaga aaattaaatc
    23641 acgacgtaag gtacttgtgc tggagaaagt gatttctgcc agctctttta cggcaattct
    23701 ttttttcttt ttaataattt caatcaattc aagtacacgt tcatctttta tcataagctc
    23761 ctcctaattt atcatttcaa ctatattata gcacaaattg gaggaatttg aattattttt
    23821 atgaatattg ggttaacatt taaacattat tcaagtaagc gttcacatat tgaaaaaata
    23881 aaacgtgggg attataataa agttaatcaa ggacgaagag agaagaaaaa tggaagcggt
    23941 tttagcaata gatttaggtg cgacttctgg aagagcaatc gttggttacc tttctgaaaa
    24001 taaactagta atggaagaaa taaatcgctt ttctaatcta cctattagag taaaagggca
    24061 tttatcttgg gatattgact ttctactagc taaaattctt gaaagtatcc gcttggctaa
    24121 tactagttac aagattttat ctatcggtat tgacacatgg ggagttgatt ttggactgat
    24181 tgataatgaa ggtaagctgt tattacaacc tgttcattat cgtgatgaaa gaacaaaggg
    24241 agtgttaaag gaaatatctg aaatgactga attagaaaaa ctgtattcag agacaggaaa
    24301 tcagattatg gagataaata ccttgtttca actctttaag gcacgtcaag aatctcctga
    24361 ctctttctat aagaccaata agattctttt aatgccagat ttgtttaatt atctcttgac
    24421 aggtaagttt gctacagaaa aaagcattgc ttcaacaact caattatttg atcctaggag
    24481 tcaaaattgg aatcagaata tcttaaaact atttgaattg gattcaactt tacttcctga
    24541 aattgtttca gagggaaatg tccttggaag gataaaagag gagtatggtt taggcgatat
    24601 tcctgttgtg aatgtttgta gtcatgatac agcaagcgcg attgtctcag tacctaagac
    24661 agaagatagt ttgtttattt catcagggac ttggtctttg gttggagtgg agctttcttc
    24721 acctattctt agtaccgaat ccttcagtta tggatttaca aatgaagtcg gtaaagatgg
    24781 agtgattaca tttctgaaga attgtacagg gttgtggatc atagaggaac taagacgttc
    24841 atttgaacga agagggaaag cctattcttt tgatgatatt aggacaatgg tggagaaaga
    24901 aaaagaaaat cttcctctga ttgatactga atcaactgaa tttgcaacag aatctgatat
    24961 gcacaagact ttgacagaat atctagctta tcatcatgaa actggagagt ggacagatgg
    25021 acaactattt aagatcgttt atgaaagcct agctgaaacg tataaggaaa caatagagtt
    25081 actagaagaa ctaactcata aggtttataa gaggatatat gtgattggag gaggtgctag
    25141 agccagttac tttaaccaaa tgattgctga tagaactggt aaagaagttc ttacaggttc
    25201 aactgaggct acagctgtgg ggaatatttg tatacagcta ttaagtcaag gtaaaataaa
    25261 cgaggataca gggttaaagg atattatgac aaatattgct gatacacaat attattatcc
    25321 tcagctatca taaacaaaaa taaaaaaacg gaggttttgt catgaacaaa aaaagtcttt
    25381 tgaaatgcgc tgttatcggg ttagtagcta cctttggttt agcagcttgt ggaacatcta
    25441 aggatgcaag cggtggaagt tcttctggta aagaagtatt agaattttat catgggtatc
    25501 atcatagtga agatgaatgg cctgtagcga agactatgcg agatttatat gataaatttg
    25561 cagaagaaca taaagatagt ggtgtagaat ttaaaccaac tcctgtaaat ggtgatttga
    25621 aggatataat gaataacaag gttgctagtg gtgaatttcc tgatgtgatt gacctagcag
    25681 gtaatgcagt atcattagct gcgattgaac aaaaacttgt tttagatttg aaaccatata
    25741 tcgattcaaa taagcttgaa aaaaatgttg gtttgaacta taaacaaaac caaaaagatg
    25801 gaaaaattta tacagttcac gaacagttat ttacaatggg tctgtggtac aacaaggaca
    25861 tatttgcaaa agcaggtgct aagacacctg atcagtggaa tacttgggaa gattttacac
    25921 aagcaatggc tgctgtgaga aaacaagatg gagtgtatgc atttggtgct ggagaaccat
    25981 ctattcgctt gtttaataca gtcttaggaa ccacagaaaa tgggcgtaaa ttattagaca
    26041 aaccattaac aaaagaagga attgaatcta aagaatttgc agatgctttg aagatggtca
    26101 tgaaagaaat tcaagctaat ggttctaaga atgctggtgg cgatgctaat gcgtattcta
    26161 aagacttcca agaaggtaaa tctgcagtct tctttaatgg tgtgtgggct tctggtgaga
    26221 tgtctaagaa cccaagtctt gcacctggaa tctatcctgc aggtgtagca attagttctt
    26281 ctggaggtgg tatcactatc tcaagtaaga tgtctgaagc taaacaaaaa ctagctcttg
    26341 agtttttgaa atatatgact agcgatgatg tacaaaaagt aatttttgaa aaagtaggag
    26401 caaatccttc taatgaaaat gtaaatgtaa aagaactttc agaaaagagt tcagaagcta
    26461 ctactaaaat tttaggacaa gcaatcactc aagttaagaa tgcaaaagca gttgttccaa
    26521 ctgtaagtga tgtttggggt ggcgatgtac acacagctat tatcaatgca ttgacagaaa
    26581 gtgctgctga aaatgtagat gttgatcaaa aagtaaaatc tactcaagat gtgttgaaat
    26641 cattgattgg ttaattgttt tagggagtga aaacgaagct cagttggcac tgccaactga
    26701 gcttgatttt acttatatag ttgaaaaaag gagtttgttt atggcacaaa aaattatgag
    26761 cctacaaaat aggaagaatc aaaaaagacg atttatcttt ttatttcttt tgccaacgtt
    26821 gatttgtttc tttctatttt atttttattc tgtagtaaca atctttttaa cttcatttgc
    26881 taaatgggat tatacaaatt taaacacccc tgagtttctt ggatttgata aattatttga
    26941 aaattatagg tatgttttta aagaataccc attttttaca gaagctctaa ttaattctgt
    27001 tcgttgggct gtaattggtg ttattattca agttccttta gctgtatctg ttgcaattac
    27061 attatctaag aaattaaaag gctggaagat atctaggaat ctttatattg taccaagtat
    27121 catttctagt gctgctatgg gcttgatttt tcttcaaatc tataatccaa actatggtgt
    27181 tgttaaccaa attattcatc tatttaatcc atcgtttaaa gattcagtac tgttgactcc
    27241 aggattaaat atagtagcta tgactggcgc ttatatcttc tttgcaggag catcaaccat
    27301 tatgattctt gggcaaattt ttgctattcc agaagaagtt caagaagctg ctattttaga
    27361 caatattact ggttggagga aagagtggta tattacgatt ccgatgatta aggggacaat
    27421 taaaactgtt tcaattatgg cagcaacttc aggatttttg ctctataacg aagtattctt
    27481 tttgacaaat ggtgctgcag gaacaaaaag tatcagtttt gttattcgag aattagcagt
    27541 ggctagctca cgaactcagt atgctcgtgc aaatacaatt ggagttatac aaatcttagg
    27601 tggaatgttg attatcgttt gtattaatat tttattcaga gaaagaaaaa gactgaaagg
    27661 tgggaaatga ttatgaatac acatataaat ggtattagta aaaaaggcaa agttcttata
    27721 tatggttata tgctccttac cattttaatt tctattttcc ctattgcgtg gattttttta
    27781 tcatcattaa aagcagatcc tatgaaaaat ccaggtatta gtttaccgac tgactttact
    27841 cttgaaggtt atataaatgt ttttacaaaa cttcatgttt tcacttactt ttggaatagc
    27901 tttaaagtag tgtctatatc agttattatt agcattgtta tgatctccat gtcttcatat
    27961 gttattgcta ggatggaatt tagagggaag aagttggtga cttctatgct gtattctact
    28021 ctatttattc cagcaacagc tatgactttt ccagtttata gattagtaaa tgagttgggg
    28081 atttataata ccccagttgc tctaattctg gtctactctt gtagtggaat tgctatgagt
    28141 ttctttatta taaagaacta ttttgaaatt attccaaaag aattggagga ggcagcagag
    28201 attgatggtg cgacatatgc tcaaactttt tggaaagtga tgttgccaat tgctagacca
    28261 ggaattttaa cagcagcagt acttgccttt attaataact ggaatgaata ttattgggca
    28321 tctatgttgg tgattgataa aaatgaatta acagtaccag cattactagg tcaatttact
    28381 acaagtttta atactaatta taatggtcta ttttcagcta ttgttgtaat cgtattacca
    28441 ccaatcattc tattcgcatt tacaagtaaa tacttcattg aagctttagg aggaggagca
    28501 gtaaaaggat gaaacataca cttgaaacta tcaatagtag aactcagtgg tttagagaag
    28561 caagatttgg gatgttcatt cattgggggt tatattctat tccaggaaaa ggggaatgga
    28621 ttcgtagtca tcagaaatta tctattgaag attatgaacc atattttcga gcttttgatc
    28681 ctaaggaata taaccctaga gaatgggcta aacaagcaaa agctgcaggg atgaagtata
    28741 tggttttaac ggctaaacat catgatgggt tttgtttgtt tgattcaaaa tttacagatt
    28801 ataaagcaac aaatacacct gcaggtagag atttagttaa agaatttgta gatgctgttc
    28861 gagctgaagg tttaaaagta ggcttatatt ttagtttgat tgactggcac catcctgatt
    28921 tccctaaata tgctgatcta aatcatccaa tgagaggaaa tgaagcctat cgagatgaga
    28981 aaattaactt tgacagttat ttggagtatt tgcacaatca agttaaagaa attgtaactg
    29041 gttatggtca gattgacata ttatggtttg attattctta tgaagacatg gtgggtgaaa
    29101 aatggggagc ttcaaaatta atagacatgg ttcgtcatta tcagccaaac gttatcgtag
    29161 ataatagatt agaaacatca ggtgaaggat tcggaagtat cgttacagat gaaattacct
    29221 cttacgctgg agattttgtt agtccagagc aaattgttcc tcacgaaggt attcgaaact
    29281 ttaaaggtga acctgttcct tgggaacttt gtctaactat gaataacaat tgggcttata
    29341 atcctacaga ttatctatat aagtctagtc aaactttgat aagaaagtta gtggaatgtg
    29401 ttagtaaaaa cggaaatatg attcttaatg taggcccaga tgctttggga agaattaatg
    29461 attcaagtaa gaaaatatta gataattttc atcgatggat gtctcgaaat ggtgaggcaa
    29521 tttatggatg tagtggagat gaaaatttac caaaaccaga ttggggatac tatactcgta
    29581 atggaaatac ggtttatgct catgtatttg aacaacctat aggtccttta gctcttcttg
    29641 gtattagtaa agaaaacgta aaaagaatga gctttcttca tgatggaagt gaggtgaaaa
    29701 tttcagaaag ctggacgacc aatgcctaca aaggaatttg ttttgcacag tttggagaag
    29761 ttccacattt tacctatcca ttaccagact tgattgatag cgtaatcaaa attgagttga
    29821 gagagtagtt tatatgaaaa ttgaaaataa aaatgtaaga cgtaatttct tttggggaga
    29881 tggtcgattt tatactactg atatcgtaaa caaacgggca ggagtaatga tagaaaatgt
    29941 ttcgaaagaa gaatttacca ttacattgga gaatggtata agactttctt caaatcattt
    30001 ttcagcaatc gttagggaag agggagatac gcgaattcag gtttcttttg tttgtccttc
    30061 cattcgttta cgtttaatct ttgaatcgag ggatgatgtt ctttcgaagc aattagtttt
    30121 agaatcatct actgaggtta ttaaatctgt agaggtagag agttttgagt ttgaaacaga
    30181 agacaatatt ttctatccga aaagacaaga ttgtattaag gaaatggcga atttttccgg
    30241 ttattatgta gaattgggac aacctgttta tgcgaattct ttattcttag gaatggaatt
    30301 tccaatgtct gaaaacaagg tagatggtag acattatgta tcaagatatt actttggaac
    30361 tgttgtaaat caagaaaaga gtttgtggtc ttgtattatt gggggagcat gttcttataa
    30421 aaaagaagag attcaagagg cattttttga atatgttgaa ggaatagctc aacctagtta
    30481 tttccgtaaa cagtataatt cctggtatga ccatatgacc gatattacag aggaaggtat
    30541 tttaaaaagt ttttctgaga ttcgagatgg atttgaaaat catggagttc atttagatgc
    30601 ttatgttgtt gatgatggtt ggacaaacta tcaatcagtt tgggaattca atcataaatt
    30661 cccaaatggt ttgagaaata ttaaatatct tgtaaatgga tttggttcaa gcctaggatt
    30721 gtggattggt ccccgaggtg gttataatgg gacagaaatc attatgagtg attggttaga
    30781 agcacatcca gagttaaata ttggatctaa aaatttgatt tcaaatgatg taaacgtggc
    30841 tgattttaac tatctcaatc aaatgaagaa aaagatgttg gaatatcaaa aagaattcga
    30901 tatcagctat tggaaaattg atggttggtt acttcaacct gacaaacctg ataagagtgg
    30961 accgcacggt atgtatacca tgacagcggt ttatgagttc ttaattcaac tgttgataga
    31021 tctaagaaag gagagaggag gaaaagattg ttggttaaac ttgacttctt atgtaaatcc
    31081 tagtccatgg tttttacagt gggtcaatag tttatggatt caaatatctc aagatgtagg
    31141 ctttacagag aatgcaggta atgatatcaa tcgtatgatt acttaccgag atattcagta
    31201 tcaagaattt ttggaaaaac gtgagataca gttacctatg tggtcgcttt ataatcatga
    31261 accaatctat gctgtcagtg caaatacctg gtacatggat catcaaatgt ttgcatcaat
    31321 accagatttt gaagcttatc tattatttat ttcaacaaga gggaatgctt tttgggagtt
    31381 tcactattct tttgatatgt ttgatgaaga acgctggaaa gccaatgctc gtgccgtcaa
    31441 atggatagag gagaattatc aaacactaaa atatagtaaa aaaataggag gaagtcctga
    31501 aaaatttgaa atttatggtt ataagtgtca caatcagaag acttctactg aaattctctc
    31561 tctgagaaat cctgctcaga ttaaacaaaa aataaaaata gagaatcttt cgatagagaa
    31621 ttttaccaga gtaattggag attttactat tcaagaagat gagatagaat tggcaccgta
    31681 ctctatcgtg atactgaaga agtaaagaaa aaattgtgag gtagagatga cgatttatat
    31741 taataaggac gagaccgttt ttcatttggc aatgaaagat agtagttata tttttagaat
    31801 tttagaaaat ggagaacttc aacatctaca ttttgggaaa aggattcatg tcaaggaaaa
    31861 ttataatcaa ttgatggcct atgaaaaaag aggatttgaa gtatcttttt ctgaagaatt
    31921 tgaggatatt caacagtcta tgatacaaaa tgaatattct tcatatggga aaggagattt
    31981 tcggcatcca gcctttcaag ttcaaggaat gaatggtagt aggataacga cactaaaata
    32041 tcaaggtttt gaacttgaaa aagggaaaaa tcgtcttaac tctctacctt caacatttga
    32101 tgatattggt cagtgtgcgg aaacattaac gattatttta acagattcca tattagattt
    32161 aactgttaga ctaaattaca caatttttcc ggaatacaat gtcttagtta gaaatacgga
    32221 atttttaaat aatagcaata ataagttgac tcttttgaaa gcaatgagct tacagctaga
    32281 tctacctgat agtcaatatg actttattca attttctgga gcatggctga gggaacgtca
    32341 gttatataga acttcgctta gaccaggtat tcaagcaata gatagcttga gatactcatc
    32401 aagtcctcag caaaatcctt tctttatgct atcaaggagg gaaactacag agcatagtgg
    32461 tgaggtttat ggttttaact ttatctattc tggaaatttt caaaatatga ttgaagttga
    32521 ccattttgac accgctagag taacggtagg aataaatcca gtagaatttc gttttttatt
    32581 aaatcctgcc gaaagttttg tgacaccaga agcaattgtg atctattctg atcaagggat
    32641 gaatcagatg agccaacaac tatcagattt ttatcgacat catttagtta atcctaattt
    32701 ttctcaagct agtcgtccta taatactcaa tagttgggaa acattttatt ttgacttggg
    32761 tacagaaaaa attttagatt tagcaaaggc tgctaaagat ttagagatag aattatttgt
    32821 actggatgat ggttggtttg gtcataggaa agatgacaaa agttctctgg gggattgggt
    32881 aacagataga agtcgccttc ctgaaggtat tggatttctt gcagataaaa ttcacaaaat
    32941 aggtttacaa tttggtttgt ggtttgagcc tgaaatgatt tctattgata gtgatttgta
    33001 caagaatcat gccgattgga ctatccattt gttagacaga gagaagtcag taggaagaaa
    33061 tcaatatgtg ttggatttga cgagacagga agttgttgat tacctttttg attctatttc
    33121 taaaatcata atcaaaacaa atctggatta tatcaaatgg gatatgaatc gtcatataac
    33181 agatatttat agtattgaac ttgattctga acagcagatg gaatttggtc atcgatatat
    33241 cttaggtctt tatcagctat tagatcgttt aataactaag ttcccttcag ttctatttga
    33301 atcttgttct tcaggtggtg gacgttttga tttaggactt atgtattatg caccgcaagc
    33361 gtggacgagt gatgatacgg acccgataga aagattgaaa attcagcatg gaacttctta
    33421 tggatattct ccatcaatga tgacagccca tgtttctatt tctccaaatg aacaaagtag
    33481 aagacaaacg agtttggaca ctaggacaaa tgtagcttat tttagttctt tcggttatga
    33541 attagatgtt acgagattgt cggtagaaga aaaagaacaa gtgagagaac aaattcagtt
    33601 ttataaaaaa tatcgttcat tgtttcaata tggggatttc tataggataa acagtccttt
    33661 tagttgtgat tctgctagtt ggcaagttgt ttcaaaagat aaatgccaat cgattttatt
    33721 gtatgctcaa ttgaatagta agttgaatcc aggttataca agagtttatt ttagtggttt
    33781 agataaagat aaatgctatt ccgtctctgg atttgatgag ttcttttatg gagatgaatt
    33841 aatgaatgct ggaataaaag tcagtttaag taatttagca ctttgtgttc cagaatatct
    33901 tacaaaatta tttgttattg aggaagttgt atgtaaatat tgaggaaata aaaatggaaa
    33961 gtaaaaaaat agcaaaacag attttaatag ctacggctgt tttaacaagt tttttaggaa
    34021 gtaatttggt ttatgcagat gtagttcaaa gtaattctaa taacagagct agtactgaaa
    34081 ctgttagagt aacagggaat aacttagaaa aacttattac taaagataaa gaaattgata
    34141 aagagatgac atatctttca gatatggatt ggtcttctgc aactcatggt gatatagata
    34201 aaacaaaaac agtacaaaaa gatgctccat ttacaacagg aaataaagga gagcatacta
    34261 agatttcatt gctcacttct gatgataaag ttaaatattt tgataaagga ataggaacag
    34321 tcgcagattc tccatcagta atcagctatg atattagcga tcaagggttt gaaaaatttg
    34381 aaacttatat aggaattgat caaagtgcta atagttctag atcagaccat gcagtagtgg
    34441 atagaataga aatagaaatt gatggaaagg ttgtctattc tagtagtgta actaatccag
    34501 aaggattcag atataatacc caggcacaat ttattagtgt gacaattcca caaaacgcta
    34561 aaaaaatatc cttaaaatca ttcgcaggag aacatacatg gggtgatgaa gttgtatttg
    34621 ctgatgctaa acttattaaa actgttagta ctcaaactat aactccagat cttcttaata
    34681 aaggaattaa tggaggagta tatctttctg atttagaatg ggttgatgct actcatggtg
    34741 atgacgataa atcaaaaaca gttcagaaag ataaaccgtt tacacctggt aataacgggt
    34801 ctaataataa aataaaatta ctaattgacg gtaaggaagt cgaatttaat aagggattgg
    34861 gaactgtagc aagtaacccg tctagtataa aatatgatgt ttcgggtgct aatgttacaa
    34921 gatttatttc ctatgtcgga attgatagga gtgcaaatca tttaaattca gattacgcag
    34981 atattcaaaa atttgaagtt gttgcggatg gtaaagtcat ttactcatca gattcaaaat
    35041 atccaaaagg aattaagtat gatacatcgg catttctggt tgatgttgaa attcccaaag
    35101 atacacagac aatagaactt aaatcatatt cagggaaaca tacatgggct gacgaattgg
    35161 ttttaggtgg agccttgttt atggcaaatg gtaaatttaa gaatcctaat gattggtcag
    35221 aagttgataa acgtcgtgaa attaataatg aacatccgtt acttatgatg cctttatatg
    35281 ctaacggaga agagtttaac caagggaaat atactttttg gggaggagat acattaacag
    35341 gtaagtggga gaatatacca gatgacttaa aaccatatac tgttatacag ttacatccag
    35401 atgatcttcc taaaagagat ggagctgcta gagattttta tgaacatatg ttagaagaag
    35461 cagcgaaata tgtaaatcct aagactggaa aaaatgaacc aattccagtt attctgacgg
    35521 tttacactgc tggtaatatg ccttattata cttcggcaca ttggttaagt accagctgga
    35581 ttgataaaat gtatcaaaaa tatccaaatt tgcatggtat tttcagtaca gagaattatt
    35641 ggatttgggc aaatgatatt gaaaataagg cggcagatta cttaaaagta tcagctaaaa
    35701 atggaggata ttttatatgg gctgaacaaa ataatggttc tgcaatagaa aaagcatttg
    35761 gaaaaaacgg taagatagca tttcagaaat ctgttgataa gtactggaag aaccttattt
    35821 tcatgttcaa aaatacacct gctgctgagg gaaatgattc aactacagaa agttatatga
    35881 agggactttg gctttcaaat catacttatc aatggggtgg tttgatggat acttggaagt
    35941 ggtatgagac aggtaaatgg aaactgtttg caagtggtaa tatcggaaaa agtcaaggag
    36001 atagacaatg gttgactgaa ccagagtcta tgctaggaga agaagcttta ggggtttacc
    36061 ttaatggagg tgtagtttat aattttgaac acccagctta tacctatggt gtaaataata
    36121 aagaaagctt actctttagc gaagtaataa aagaattttt tagatatgta atagcgcatc
    36181 cagcaccatc caaagaaaag gtacttgagg atacaaaagt attcatacat ggagactatt
    36241 caaataaagg aaatggtaag ttctttgtaa acgtaaatac tgatagagaa caaactccat
    36301 tatacatgac tggtcgttat aatgttattc cagctattcc aggtgtttta aaaacagata
    36361 aattgaaaga gtctgtttct ggtagccgta ttcagattaa ggaaatcact tctccagaat
    36421 ttagctctac tcaggctaga aaagaatact taaataagct gtatcctatg aattatgaag
    36481 gagatatctt tgctcagaaa ttagataata gatggtttgt ctataattac aaggtaaatg
    36541 agaatgttaa acagactggg aaattaaaat ttaattcttt agaaatggat gttgaatttg
    36601 aacctcatac ctatggtatt tttgagagaa taagtaatgg attgaaagtg aatttaaata
    36661 attttagaac aaataaagat tcactatggt ctaatgctca agatgcaaat caggcaaaga
    36721 aactaccaca attgaccaag aaaggtgcga ttaagtggat tgaagaacat tatatcaaag
    36781 atactcagtt tggagagaaa agggttacaa agatagtatt aagaggtata gataaacttc
    36841 ctactattca ttcattatca ggaacaaata attcctatga tcagccatct ctcaattttg
    36901 atcagaaaaa tcatatggtt actattacca ttaacagtaa cggaaatctt gaattcgaac
    36961 ttcattttta gaaaggagtg agtttatgtc tcaagatgaa aaattaattc gtgaacagat
    37021 ttgtgatgtt tgtcataaga tgtggcaact tggttgggtt gctgctaacg atgggaatgt
    37081 atctgttcga ttagatgagg ataccattct tgcaacacct actggtatca gcaaaagttt
    37141 tattacacca gaaaagctgg tgaagttaaa tcttaaagga gagattttag aagcagaagg
    37201 tgattactgt ccttctagtg aaattaaaat gcacattcgg tgctacgaag aacgtgagga
    37261 tgttcgttca gttgttcacg cgcatccacc gattgcaaca ggatttgctc ttgcacacat
    37321 tcctttagat acttattcac taattgagag cgcgattgtg gtaggggcaa ttcctataac
    37381 gccatttgga gttccgtcta caatggaagt gccagaagca attacacctt atctgcccga
    37441 tcatgatgtc atgctattag aaaatcatgg agctctgact gtcggaagcg atgtcattac
    37501 agcatactac cgtatggaaa ctttagaatt agtcgcaaag acaaccttcc acggaagaat
    37561 gttactttct acaaagggca ttgaggagca agaaattgct cgtccgactt tagaacgtct
    37621 attctcaatg cgagaaaatt ataaggttac aggtcgtcac ccaggctacc gtaaatataa
    37681 tggcgatggt agtatgaaag aaacagaaaa ataagaggaa aatagtatga ttcaacatcc
    37741 acgtattggt attcgtccga ctattgatgg tcgtcgtcaa ggtgtacgcg aatcacttga
    37801 agtacaaaca atgaacatgg ctaaaagtgt ggcagatttg atttcaagca cattgaaata
    37861 tccagatggg gaacctgtgg aatgtgtgat ttctccatct accattggtc gtgttccaga
    37921 ggctgcagct tcccatgagt tgtttaaaaa atcaaatgtt tgcgcaacaa ttacagttac
    37981 accatgctgg tgttatggta gtgaaactat ggatatgtct ccagatattc ctcatgctat
    38041 ttggggattt aatgggacag aacgcccagg agctgtctat cttgcagctg tactagcttc
    38101 acatgctcaa aaagggattc cagcctttgg gatttatggt agagatgttc aggaagctaa
    38161 tgatacagat attccagaag atgtcaaaga aaaactttta cgttatgcgc gtgcagctct
    38221 tgcaactggc ttgatgagag acactgctta cctatcaatg ggtagtgttt cgatggggat
    38281 tggtggttct attgtaaatc cggatttctt ccaagaatac ttaggaatgc gaaatgaatc
    38341 ggtagatatg acggagttca cacgccgtat ggaccgtggt atttacgacc ctgaagagtt
    38401 tgaacgtgct atggtttggg taaaagaaca tatcaaagaa ggagttgacc gaaatcgtga
    38461 ggatttgatt ctttctaaag aagagaaaga aaaacaatgg gaatttgtta ttaagatgtt
    38521 catgattgga cgtgacttaa tggttggtaa cccaagactt gctgaacttg gttttgaaga
    38581 agaagcagtt ggtcaccatg ctttagtagc tggtttccaa ggtcaacgtc agtggacaga
    38641 ccattttcca aatggagatt ttatggaaac tttcctcaat actcagtttg actggaatgg
    38701 tattcgaaaa ccatttgtat ttgcgacaga gaatgattca ctaaatggtg tgtctatgct
    38761 ctttaattat ctattaacaa atactccaca aatctttgct gatgtgcgta cttattggag
    38821 cccagaggct gttaaacgtg taacgggaca tactttagag ggtcgtgctg cagctggctt
    38881 cttacatcta atcaactctg gatcttgtac attggatggt acaggtcaag ctactctaga
    38941 tggcaaacct gttatgaaac cattctggga gttggaagaa agtgaagtgc aggctatgct
    39001 tgaaaataca gacttcccac cagcaaaccg cgaatacttc cgtggaggag gattctcaac
    39061 tcgtttcttg acgaaggggg atatgccagt aacaatggta cgtctcaatc ttctaaaagg
    39121 ggttggtcca gtgctacaaa ttgcagaagg ttacacactt gaacttcctg aagatgttca
    39181 ccatacttta gataatcgta cagatccagg atggccaact acttggtttg ctccacgttt
    39241 gacaggaaaa ggtgctttca agtctgtcta tgacgtcatg aataattggg gagctaatca
    39301 cggagccata acatatggac acattggagc agacttgatt accttggctt ctatgttgag
    39361 aattcctgtc aatatgcata atgtacctga ggaagatatc tttagaccta aaaattggtc
    39421 cttatttgga acagaagatc tagaatcagc agactatcgt gcatgtcagt tgttgggacc
    39481 actacataaa taaaacttgt ttatatagga ggtgaactta cgtccctcct atccttttaa
    39541 aaagatttgt taaacaattc acaaataatt gaaaacgaat acaaaaagta atataatgat
    39601 gttaaataga tagcgcggag gcgcaggagg aaaattatat ggctatattt tatgttccgg
    39661 cagtcaacct tattggaaaa ggtgttgtaa atgaagtggg gccttatatc aaggaacttg
    39721 gctataaaaa ggcacttttg gtgacagata agtacatcga aggcagtgat attttaccta
    39781 agactttaaa accactggat acagaaggaa tcgaatatgt catctttagc gatgtagagc
    39841 caaaccctac ttgtaaaaat gtcacagatg gggtagctgc tttgcaagaa catggctgtg
    39901 actttatcat cagtcttggc gggggttctc cacaggatgc agctagttgt atttctatca
    39961 tggctacaaa tggtggaaaa ccacaggatt atgaagggct tcataagtct gctaaaaaag
    40021 gcttgccagt tgtggctatc aatacaacgg caggtacatc agcagaaatt accattaact
    40081 atgtgattac tgatgaagaa cgcaaggtta agatggtaat ggttgacaag aatagccttg
    40141 ctcttatctc tgttaatgac ccggaactca tgctttccaa acctaaaggc ctgactgctg
    40201 ctactggtat ggatgctctg actcacgctg ttgaagcttt ggtaacacct ggtgcttatg
    40261 atgtaaccaa gaaactgtct attggtgcta ttgagcttat caaggaatat cttcctcgtg
    40321 ctgtagaaaa tggacatgat attgaagcgc gtgaaggtat ggtcaatgcc atcttccttg
    40381 gtggtatgag ctttaataat gctggtcttg gttatgttca ctcaatggct caccaactcg
    40441 gtgcagtata taatttgcca catggtgttt gctgtgccat gttgctacca gttatagaac
    40501 gtgaaaatgc taaacgtgta ccagaagctt tccgcaatgt tgccaaagcc ttgggacttc
    40561 atgtagaagg taaatcagat caagaatgtg ccgattatgc gattgttgag attgagaagc
    40621 tttctgagac agtaggtatt cctaagaaac tgactgaact tggtattgaa gaaaaagatt
    40681 tcgactttga atacctttct aagaatgcct tgattgatgc ctgcgcacca ggaaatccat
    40741 ttatgccaac cttagaagaa acgattgcct tttataaaga gttattttag caagagattg
    40801 gacgacaata ggacaattca cctctaatta ttgacatttc aggaaaaatc gcagtaaaaa
    40861 cggcacagcc ttctttaaat gtgctataat actagaaaaa tacttgtgga ggttccatta
    40921 tggcaatatt tttcatgatt tttctgattg tttgtgtgct cctattggtg atagtcacac
    40981 tgagtacagt ttatgtggtt cgtcagcagt cggtggcgat tattgaacgc tttgggaaat
    41041 accaaaaggt tgccaatagc ggtattcata ttcgcttgcc ttttgggatt gactcgattg
    41101 cagcacggat tcagttgcgc ttgttgcaaa gtgatattgt ggttgagact aagaccaagg
    41161 acaatgtgtt cgttatgatg aatgtagcga ctcagtaccg tgtcaacgag cagagcgtga
    41221 cagatgctta ctataaactc atacgtccag aatctcagat taaatcttat atcgaagatg
    41281 ctcttcgttc ttctgttcca aaattaacct tggatgaatt gtttgagaaa aaagatgaga
    41341 ttgcccttga ggttcaacac caagtagcag aagaaatgac cacttacggc tacattatcg
    41401 tgaaaacctt gattaccaag gtcgaaccag atgcagaagt taagcaatcc atgaatgaaa
    41461 tcaatgcggc gcaacgtaag cgggtcgcag cacaagaatt ggcggaagct gacaagatta
    41521 aaattgtcac tgcagctgaa gcagaagcag aaaaagaccg ccttcatggt gtggggattg
    41581 cccaacaacg taaggcgatt gtggatggat tggcagagtc tatcaccgaa ctcaaggaag
    41641 ccaatgttgg catgacagaa gaacaaatca tgtctatcct cttgaccaac cagtatttgg
    41701 ataccttgaa tacctttgcc tctaaaggaa atcaaactat ctttttacca aatactccaa
    41761 atggtgtgga tgatatccga acacaaatct tgtcagccct tcgcgctgag aagaaataat
    41821 agactaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgctttgc cgtatatttg
    41881 agctgacttc gtcagttcta tctgcaacct caaaacagtg ttttgagctg acttcgtcag
    41941 tcttatctac tacctcaaaa cggtgttttg agcaacctgt ggctagtttc ctagtttgct
    42001 ctttgatttt cattgagtac aaagagcttg gcaacaggct ctttttgtat tgcgtttatt
    42061 aagaaaaaca aaaaacatcg atatacattt aactaaaaat tattgtatgt tatctccctt
    42121 aattaggaat gataagggaa taactagaaa gatttgtgaa tacaaactat ttctgatata
    42181 caaaatatac agtaataatg aatgatggga gatgggatga aagaatttca atttgagaga
    42241 aagcagcgtt tttctttgag gaaatatgca ataggagctt gttcggtctt gctaggaacg
    42301 agtttatttt ttgctggtat gggtgctcag cctgtacagg atacagaaac gagttcagca
    42361 ctaatttcaa gtcattattt ggatgagcag gatttatctg aaaagctgaa atctgagttg
    42421 caatggtttg aattagaaaa caagcttttg aacttatggg agtattaggt tactatgaag
    42481 gatttgttcc ttacgtttca aatcaataca aaaaccaagc tgaagaagaa gacaaaccgc
    42541 tatctgataa atatattttc gaaaaaatct taggaaaaac atatgcagcc ttcaaaaaag
    42601 atcaaattaa tgagcgtgtc gagaaattag gtaagttaaa acctattaca ataaattaca
    42661 acggaaaatc agaagtaatt gatagtaaag aaaaattaca agagcttatg aataaagccg
    42721 ttaaagacga agtggctcaa atatcgtaaa atgaaataag aacaggacaa atcgttcagg
    42781 acagtcaaat cgatttctaa aaatgtttta gaagtagagg tgtactattc tagtttcaat
    42841 atactataaa atcaggcaat accacggcta aaaagtttga gtttatcgaa acaccagtgc
    42901 aaaaactgaa aaaatcgatt tataaagctc atctcaaaga ttcagatgac tttagaccag
    42961 aaacatccac acaaatcttt ttgaaagctg tttgaagctt tgtccttgct ttcttagttc
    43021 atagatctga actttatctt cataactcaa tttcataata aaacacccca aaagttagat
    43081 ttattctgtc taacttttgg ggtgcagttc attaatcggt cgattttttt tggtagaaac
    43141 agttgcctga ttaagttgca agtcgataga cggcttcggc ataaatatcc atagcacggt
    43201 acaaatcttc tagaacggca cattcatttg cctgatgttc tgtctgcttc gctcctggga
    43261 ataaggcgcc gaaggctaca caatttggca tggtgcgagc aaaagtggca ccaccggatg
    43321 aaatagcagg actgttatcg ccagtctttt cttggtagat ttgcatcagt gtgctaacga
    43381 gtttactgtc ttttgcgacg tatagaggcg ctagatagtc aaactcttcg tagcggagtt
    43441 ggtagttttg tgcacatctt gtaagcaact ctactagttc ttccttatca gctaagacag
    43501 gagtccgaat gtcaatacgg atttcagaac gttcatgatt gatcatgaga cctgcgacat
    43561 taaaggatag gtgaccagaa ggttcatctg ctatatcacc aaagatttgt cttcctgtgc
    43621 cgtcttgacc tgcttgtgtt gcaagaaaac tgagagcagg gtgttcttgg agaggagcaa
    43681 gaatggtagc tagtcggatg acagcattga taccttgact agcatcctta gcatgctttg
    43741 gcactccgag aaccgttacg gtttgttcag tggattggta atcataacca gcttctttga
    43801 gaccgttaca aacctgttca tagaggggac cttggtagtt ggccttgtct ggtacaacgt
    43861 taaaggcgcc tcctacttca agctctagtt gatccgatcc agggccatga agtttgacct
    43921 gtagaagccc tttttcagca taggtcagag gaaaagatga gtcaggtgca aagcccatgc
    43981 tggcctgttc ttcgatggta ttgtagcgtg ccatgcagcg ccagagggtt tcctcatcgg
    44041 taccaaagat aaagcgtacg cgctttttga actgaatacc ttggtccagc aagcttttta
    44101 ctgcatagag agctgcgagc gaagggcctt tatcatcttg gacaccacgt ccgaataccc
    44161 agccgtcttt gatagttgct tcaaatggcg gtgtctgcca atctgcttca tcacctgatg
    44221 gaacaacatc caaatgacag agaatggcca gaagctctgc tccctgaccg atttctgcat
    44281 atccgtaata acctttaggg tcaagatagg tagtgaaacc tatgtcttga caaatctcta
    44341 aagttttttc taggacatct tggattgctt gtccaaaagg tgttccattt tctccttcat
    44401 tgagtactga aggataggaa atcaaggttt ttaatgatat aagaaattca tctttaactt
    44461 gatttgttat atctattttc atgaaatcac ctcactcact attttatagg aatggaagga
    44521 aggttccaag gagaagaagg gcgatggtca ctacaataat agcgactacg agtttgccca
    44581 tgaatttcca ccaagtacca atgttgatac gtccaagtgc aagagctccc atcacaatac
    44641 cagatgttgg tgcaatcaag ttcaagacac ctgaagcaga ttggtaagca gtgataatca
    44701 agctaggacg gacatttaca aattctccaa gtggagccat gatacccata gttgcgctgg
    44761 caagaccaga tgaagatggg atcaagaatg acataggtag atagaagata taagttacaa
    44821 cgataaagac ttgtgaagat agaccgctca agccttcttt accccagttg aggattgtat
    44881 cggtaatcat accgtcgttc atgataactt gaataccacg agcaatcgct acgatcaagg
    44941 caacactgag caagtcagca gcaccattca tgaaggaaga gataatctta tcttctttaa
    45001 gaccataaat aataccaatc aggataccca taaaggcaaa gagcattgcg ccttctggga
    45061 agtaccaagt acctagtgca gaagtagatg aaccgacaat attaccaata actggaagac
    45121 cagtcaacca agcattaaag tcatcaaaaa tggtaacgcc aaggtctgtc catggaatga
    45181 agctcaatac catcaagatg aatgtcaaca caaataagaa gagaactgat ttttgtttgc
    45241 tgctaagtgt agattctaca gatgaagatt cttctacgtt aaagtgtttc aaatcttctt
    45301 tgcgagtact ataaaccagt gacttagtcg gatctttttg aatcttatcc gcataacggt
    45361 aaacaaacca agtactaaga gcagtcaggg taacccagaa gatcagacga agtacgatac
    45421 cgtcccctgt accaactccc gcagtcgctg aagcaatacc tgtcgcaaat ggattcagag
    45481 tagatgccaa acagccgatt tgagaaccga gcaaaataat tgcaacacca gtcaggctat
    45541 caaaaccaac ggccatcata actggcacaa ggagtggata gaaggccatt gtttcttccc
    45601 ccataccata agttgtacca ccgagggcaa acaaaggcat cagtaccaaa attaacattt
    45661 tttcgcggcc cttatacttc ttcacgatag aggcaatccc tacgtcaaga gcaccagttt
    45721 tgttgacaat gccaaggaaa ccaccaacca taaggatgaa gaaggctaca tcaatcgctg
    45781 cgctcgtttc tttaatgagc gaaccttcct ctggatgagt acctagcata gcccgaatcg
    45841 gtgccatgag gacatcccaa atcccttgtg gattttgagg ctgagtctcg taaatacctt
    45901 ctataaaggc ccccgcaggg ataaaccaag ttagtactgc cataatagca atgattatca
    45961 ataatacggt gtaagatgaa ggcatcttaa accctttttt agctttttca ctcatttgtt
    46021 tttcctcctg atgtctaaca aagtgtaaaa aaccaactac tttcttaaat aaacatttaa
    46081 gaaaacgctt tctatttata tttgttttac catattaaag tctaaaaaac tagtatcttt
    46141 tgaaatattg tacatgtttt caagaataat ttctaatttg atataaagat actagaaata
    46201 gaatacatct tattagtaaa acaacttatc ctttttcaat aattgttccg ctttcagatt
    46261 caatcaaggc gcctagattt tcaagggaag taataactgc ttttccttct ggacgaccat
    46321 tgacaaaagc gatagctgct tctacttttg gaagcatgct acctggtgca aactgatctt
    46381 gtttgatata ttcttccagc tgggcaacat tcacatgttc caatttttcc tggtttggct
    46441 tgttgtagtt aacaaataca taatctacac ctgtcaaaac gatgaagagg tctgcctcaa
    46501 ccaattctgc caaacgttgg gaagcgaagt ctttatcaat aaccgcttcg acaccagtca
    46561 aatgtccatt gttttctttg acgacgggaa taccgccacc acctgcagct acgacgactt
    46621 gaccattatt taaaagagta cggatggttt caatttcttt gatgtcaaca ggttttggtg
    46681 aggcaacgac cttacgccag ccacggccag catcttcctt gaaagtcgct ccgctctttt
    46741 cggcttctgc ttttgcttct tcttctgaat agaaaggacc gattggttta ctcaagttaa
    46801 caaaagctgg atcattttta tctacgacaa cttgcgttac aacagaggca acattttttt
    46861 cgatgccttc atctaagaga gcattttgca aagcattttt caaccagaaa ccgatgctac
    46921 cttctgtcat agcgacaagt gagtcgagtg ggaaggcagg gttcttttca gagtctgatg
    46981 ccaaatgttg gagcaagaga ttcccaactt gaggtccatt accgtgagtg ataatcaaat
    47041 catctccatt tttaatcaat tttacaagat gcttagctgt ttcaactaaa gcttcttgtt
    47101 gagcttttgc tgatgggtca gaagaaagaa tcgcatttcc tcccaaagct actacaattt
    47161 tacgatttgc cataaattct cctttatcac actcaataga atgcgtttag atttcaattt
    47221 aatgattttt cacatatttt ataagaaata atagattacc attatataaa agaggaccgg
    47281 actaaagcta ttagtcgcag cccccatagc tgttggtaga cggtttatta tctaaaatta
    47341 tactttagga atataaaggt taccaagtgt agcagccata acagctttga tagtgtgcat
    47401 acggttttct gcttgatcga agtggcgagc gtacttgctg cggaagactt cgtctgttac
    47461 ttccatttct tctacaccaa atttttcagc aacgtcttta ccataaacag tgtgagtatc
    47521 gtggaatgct ggcaagcagt gtaggaagat caagttttca ttgcctgctt ttttaactaa
    47581 gtccatattg acttggtaag gtttaagaag agctacacgt tctgcgaatt tgtcttcttc
    47641 acccattgat acccaaacgt ctgtgtaaag aacgtctgca tctttaactg cttcatcagc
    47701 atcttcagtg atgagaacat gtgcgccact ttctttagca aatccttctg ccaattcaac
    47761 gatttctttt tctgggaaga gttcttttgg tgagaagatg tgaacattga caccaaggat
    47821 agcacctgtt acgagcaagc tgttggcaac gttgttacgt ccatcaccac agtataccaa
    47881 tgtcaagcct tccaagcgac cgaagttttc ttgaacagtc aagtagtcag cgagcatttg
    47941 agttgggtgc cattcgtcag ttagaccgtt ccatactgga acgcctgaga attctgccaa
    48001 ttcttcaacc atacgttggc tgaatccgcg gaattcaatc ccgtcaaaca tacgtcccaa
    48061 tactttagca gtatcttcag tagattcttt tttacccaac tgaatatcat ttgctccgag
    48121 gtattctggg tgagcaccaa ggtcgatagc cgcagttgta aaggctgcac gagtacgagt
    48181 agatgttttt tcaaatagga gagcgatatt cttgccagca aggtagtggt gttgaatatt
    48241 gcgttttttc aaatctttca agtgagctga aagaccaata aggtattcta actctgcacg
    48301 ggtaaagtct ttttctgcta agaagctgcg tccttggaat actgaatttg tcattttatt
    48361 atttcctctt tctatttttt acattttcta ttgacgaata ccgaacagcg attacacttc
    48421 ttcacgttca aatggcatag acatacaacg aggtccacca cggccccgaa ccaattcact
    48481 tccgcgaatc ttaatcaagc gaagcccgta ttcttccaaa atcttattgg tcacggtatt
    48541 gcggtcataa acaactacca caccaggtgc gatggtcaaa gtgttagaac cgtcgttcca
    48601 ttgttcacgc gcagctgcta cgatattgcc accaccgcaa cgaatcaaat gaactttttc
    48661 tacaccaagg ttttgagcaa gaagttcagc taagtcacct ttctcttcaa cgattttaag
    48721 tttttcgttt tcgtaagtaa ctgagtaaac gtgaaggtcg ccttcgattt ctgggtgaat
    48781 agtgaacttg tcatagtcta ccatagtgaa gacagtatcc aagtgcatga atttacggtt
    48841 gttagcaaat tcaaaggcca aaactttctt gaagccaaca tttttcttga agatgttgac
    48901 caaaagtttt tcgatagaag ctgcgtctgt acgttgagag atacctactg caaggacgtc
    48961 tttagaaaga actagctcgt ctccaccttc gatacgcgta tcttcttcac ggttgtagac
    49021 caaatccact tttccgccat agattgggtg gtatttgaag atatacttac cgtagagtgt
    49081 ttcacggtta cgagtgtctg caaacatgtg gttaagcgat acggcgtttc caattgttgc
    49141 aaatgggtcg cgagtgaaat agaggtttgg catcgggtca attgcaaatg gataatcgga
    49201 ttcaactaag tcagttagat ctttagcttc gtcaggaatt tctggcaatt caactttttg
    49261 aatcccagcc attgtttttt caaccaattc ttggttgtcc ttgatgccgt gaagtaattc
    49321 acgaatagca accttggttt gacgatcacg gatgttggct tcgtctaagt attcctcgat
    49381 aaattgatcg cggatttctg gagaggtcaa tgattcagca gcgagttgtt ctaggtagag
    49441 aacctcaatt ccttcatcgc gaagagcttg ggcaaatgca tcatgttctt tttgagcatc
    49501 ttccaagaaa ggaatatcat caaaaagaag cctttcaaga tagtccggca acaagttttc
    49561 taactccttg cctggacggt gtaacataac ttttttcagt ttcccaattt ctgagaagac
    49621 ctgaattgga tgtgaagaca tgtattttcc tccttaaaaa ttttgacttg gcaccatttt
    49681 gggtaccgct tacatgtatg ttataacgca attcctaggt aatgtcaatg gctataattt
    49741 ctcggaaaat aatataaatt atgatattta gcacaatttt atgttattat acacaacata
    49801 ggatgtaata catatataca aatgcataaa cttctattaa aaaggatata aaattttttt
    49861 aaaaaatttt tcaaaaaata tacaaatgac caaaaagtgt ccaattatca tctggttatc
    49921 acttggatct gtataaagag aaatgtttgt gtgaaaggat aaaaagatgc aacattcttt
    49981 tgaagataga ttttggagaa gcatttcttg ttcaattgta caaattatag aatcttttct
    50041 gagtatttag gaagagataa ttatcttatt gaccctcttt ttattttttg ttatagtcga
    50101 cgaggtgata gtttagaata atcacttatt cacaatctgt ggaaaagtct ggagagtgaa
    50161 tggtcttcac acaatgacct gaaagaagcc tgagaataat tatggagagt agcattctga
    50221 gaggtgttag cagaaccata tgacagagct gtttgaagag ggaatattga ggagagaaat
    50281 cctgagccta ccagttggag ttggaaagag ctggctgtta gatcatggtt tattatccac
    50341 aacctgtgga taaccttgtg aacaagagaa gttgctaaag aaggagatat ataacgatga
    50401 agaaaatcaa accgcatgga ccgttaccaa gtcagactca gctagcttat ctgggagatg
    50461 aactagcagc ttttatccac ttcggtccta atacctttta tgaccaagaa tgggggactg
    50521 gacaggagga tcctgagcgc tttaacccga gtcagttgga tgcgcgtgag tgggttcgtg
    50581 tgctcaagga aacgggcttc aaaaagttga ttttggtggt caagcaccac gatggctttg
    50641 tcctttatcc gacagctcac acagattatt cggttaaggt cagtccttgg aggagaggag
    50701 agggcgactt gctccttgaa gtatcccaag ctgccacaga gtttgatatg gatatggggg
    50761 tctacctgtc accgtgggat gcccatagtc ccctctatca tgtggaccga gaagcggact
    50821 acaatgccta ttatctggct cagttgaagg aaatcttatc aaatcctaac tatgggaatg
    50881 ctggtaagtt cgctgaggtt tggatggatg gtgccagagg agagggcgcg caaaaggtta
    50941 attatgaatt tgaaaaatgg tttgaaacca ttcgtgactt gcagggcgat tgtttgattt
    51001 tttcaacaga aggcaccagt atccactgga ttggcaatga acgagggcat gcaggtgatc
    51061 cactgtggca aaagatgaat cctgataaac taggaacaga agcagagctg aactatcttc
    51121 agcacgggga tccctcgggc acgatttttt cgatcggaga ggcagatgtt tccatccgtc
    51181 caggctggtt ctaccatgag gatcaggatc ctaagtctct cgaggagttg gtcgaaatct
    51241 actttcactc agtagggcga ggaactccac tcttgcttaa tattccgccg aatcaagctg
    51301 ggctctttga tgcaaaggat attgaacgac tttatgaatt tgcgacctat cgcaatgagc
    51361 tctataaaga agatttggct ctgggagctg aggtatctgg tccagctctt tccgcagact
    51421 ttgcttgtcg ccatttgaca gacggccttg agaccagctc ttgggcaagc gatgcagact
    51481 tgcccatcca gttagaactc gatttaggtt ctcctaaaac ttttgatgta attgagttaa
    51541 gagaagattt gaagctaggg caacgaatcg ctgcttttca tgtgcaagta gaggtggatg
    51601 gtgtctggca ggaatttggc aggggcttca cagttggtca taagcgcctc ttgcgaggtc
    51661 cgctagtaga ggcacaaaag gtgcgcgtga tgattatcga ggcacaatct attcctgtat
    51721 tgaccaagat ttccctttat aaaactcctg gattatcaaa aaaagaagtt gttcaggaac
    51781 tagcatttgc agaaaaaagc ctagctgtgg caaagggaga gactcttcat tttaggattg
    51841 aacgtagtga aagtagctcc tctttagagg ctaagatttc gattcaaccg gggacaggtg
    51901 tccatggtgt cgcctatcag gatgagattc aagtccttgc gtttcaagct ggtgagactg
    51961 aaaaaaggct gacgctacca accttgtatt tcgcaggaga taaaaccttg gatttctatc
    52021 tgaacctaac ggtggatggt cagcttgtgg atcaacttca agtccaagtt tcataaaaga
    52081 agaacctttg cgcgatgcaa aggttctttt ggttattagt gatttggtag ccagctgagg
    52141 gtgaaagtta gttgttcagc ttttaggagg tcttggtgtt gaatagttga tacgagtgtt
    52201 ttgtccagtc ggcattcttt gacaaagtta aaatggttgt ggttttgttt agtatggata
    52261 tccagccatt tatcttcttt agctaagtag actcgtagat ggtcaaagag agggattccg
    52321 aggtcatagc ttggttttcc tggacaggtt ggataaaatc cgagagctga ccagatgtac
    52381 caagcagaga gactaccatt gtcttcatct ccaggatagg cttcccaact tggctgaaaa
    52441 gctttctgac ggagcgtctt gataagaagg gcagtgtagt cagggtaatc gctgtagcgg
    52501 aagagataag ggatgtggaa actaggctgg ttggaaatgg ctatttgtcc aaaaggagca
    52561 gtagccatct cgctcatttc gtgaatttca taaccatagc ctgttgtttc aaagagggga
    52621 gcatcttgac aagctttcaa aagatagttg ctaaaggttt cttttccacc cataagttgg
    52681 attaagccag ggatgtcgtg gagaacgcct aaagtagctt gaatggcaga gcattcagcg
    52741 tagtctcgcc cccaactata aggagagaag tcagggtgaa agtttccttg attgtctcgt
    52801 gctcgcatgt aacctgtctc agcgtcaaat agctggcggt aattttgtga agcagccttg
    52861 taggtttcag cgatttctat gttctctagt tttttggcac agctagcgat acaaaagtca
    52921 ctataggcat agtctagagt atggctaaca ctttcgtggt ggtcggtaga gaggtaacct
    52981 agttcttggt attgggctag tccgtggcgg ccattgattc cgagagggtc ggctttgctg
    53041 gctgtttcga gcatggcttg gaagagttct ccttctaggt caggggccat gtccttgcag
    53101 gcgctatctg cgataatacc gtctaaaagt gtacctggca tcataccccg ttcatctgga
    53161 gccagccatt ttggaaggaa accagtatcg cggtagctat tgaggaaacc ttctaaaaag
    53221 cgttgatagt gctccggtat gataagggca aagaggggga aggtggtgcg gaaggtatcc
    53281 cagaaaccat tgttgctaaa gaggacacca ggcttgacag taccagtagc cagatccatg
    53341 tggatggctt gccctgactc atcaacctca taaaaagtct gtgggaagag gaagagtctg
    53401 tagaggcagt ggtcaaagaa ggttcggtca gcctctcctg tctctataat gtcaaaacga
    53461 tggaggagat tttcccaatc cgcttgggca cttgttttac agctatcaaa atcttcttga
    53521 ggtagattga ttagagcttg agaaggagag atgaaagaag tggctagttg catctcggtt
    53581 tgactacttg ctaagtcaat tcgccagtct ccagcttctt ggctgatagc aagaatatcc
    53641 gtgttcattt gcagggcagt gaagagcatc agtggatttt tattggtctc tgttttccct
    53701 tcttgtctga gagccagagt ccgcttatct acctgctcaa ctgttagttc atctgctgcg
    53761 tgaagataga gggagagggc tttgccttgc ttttgcttca aacgaataga agcaccatag
    53821 caagtcggtg tgagctgggt ttcaatctga tagcgtaggg agaaaatctt tagataatga
    53881 ggttggaaag aggccttatc cctatcatag gaagattggc ggtgaaagag gctgtctcca
    53941 cccagttgac tggtgacagg tgtcagaagg agccaagagt agtccccaat ccaaggactg
    54001 ggctggtgag ttaatcgaat cccctgaaag ataggcagat gcggatcgaa gaaccaagat
    54061 ccatcctggt cactggtctg gggcacaaag taattcatcc caaaaggcac gcctgtgtat
    54121 ggcagggtat ttccccgaga aaaggcatgc ttgttggtag ttcccaagcg ggtatcgatg
    54181 gtttcaagta gtggtttcat agtctttcct ttagctgttt ttctacatta tatcagaaaa
    54241 agagggcctt tagaaaagga gtttcaaaga taactatttt gtagaaaaat gactatcatt
    54301 tgtgtatgta ttttctgtct caaaagctat atactgaaca tgaaacttgt ttgaaagagg
    54361 gaattgcacg atgatttatt cgaaagaaat tgttagagaa tggctagatg aagtagcaga
    54421 gcgggctaag gaccatccag agtgggtgga tgttttcgag cgttgctaca ccgatacctt
    54481 ggacaatacg gttgaaatct tagaagatgg ttcaactttt gtcttgactg gggatattcc
    54541 tgccatgtgg cttcgagatt cgacagccca actcagaccc taccttcatg tagctaaaag
    54601 agatgccctc ctgcgtcaga ccattgcagg tttggtcaaa cgtcagatga ccttggtact
    54661 caaggatccc tatgctaact ccttcaacat tgaggagaac tggaaagggc accacgagac
    54721 tgaccacaca gaccttaacg gctggatctg ggagcgcaag tatgaggtgg attcgctttg
    54781 ctatcctttg cagttggctt atctcctctg gaaagagact ggcgagactg gtcagtttga
    54841 tgagactttt gtcgcagcga ctaaggaaat tctccatctg tggacggtgg aacaagacca
    54901 caagaactct ccttatcgtt ttgtccgaga tacggaccgt aaggaagaca ccttggtaaa
    54961 tgatggcttt ggacctgact ttgcagtgac aggtatgact tggtcagcct ttcgtccgag
    55021 cgatgactgc tgtcagtata gttacttgat tccgtcaaat atgtttgctg tagtagtctt
    55081 gggttatgtg caagaaatct tcgcagcatt aaacctagct gatagccaga gtgttattgc
    55141 tgatgccaag cgtcttcagg atgaaatcca agaaggaatc aaaaactacg cttacaccac
    55201 caacagcaag ggcgaaaaga tttacgcttt tgaagtggat ggcctaggaa atgccagcat
    55261 catggatgat ccaaatgtac caagtctact agctgcgccc tatctgggct actgttcggt
    55321 cgatgatgaa gtgtatcaag ctactcgtcg taccattttg agctctgaaa atccatattt
    55381 ctaccaagga gaatacgcta gcggtctagg aagttctcat accttctatc gctatatctg
    55441 gccaatcgcc ctttctatcc aaggattgac aacaagagat aaggcagaga aaaaattctt
    55501 gctggatcag ctggttgcct gcgatggtgg tacaggtgtc atgcacgaaa gcttccacgt
    55561 agatgatccg accctctact ctcgtgaatg gttctcttgg gctaacatga tgttctgtga
    55621 gttggtctta gattacttgg atattcgcta aggggctcgc tttagctcaa ccgattctta
    55681 tcagaatcac aagtttacat ttaaaacgtt aaaatttaaa tttagaatga ggttttactt
    55741 catggaaaat attgttgtac atattatctc acatagtcac tgggaccgtg agtggtactt
    55801 gccttttgaa agccatcgta tgcagttggt ggaattgttt gacaatctct ttgatctctt
    55861 tgaaaatgac cctgagttca agagtttcca cttggatgga caaactattg tccttgacga
    55921 ctacttacaa attcgccctg aaaatcgtga caaggtccaa cgctacattg acgagggcaa
    55981 gcttaaaatt ggtccctttt acatcttgca ggatgattat ttgatctcca gtgaagccaa
    56041 tgtccgcaat accttgattg gtcaacaaga agctgccaaa tggggtaaat caacccagat
    56101 tggctacttt ccagatacct ttggaaatat gggacaagcg cctcaaattc ttcaaaaatc
    56161 aggcattcac gtggcgacct ttggtcgtgg tgtgaagccg attggatttg acaaccaagt
    56221 ccttgaagat gagcagttta catcccagtt ttcagaaatg tactggcagg gtgtggatgg
    56281 tagtcgtgtt ttaggtattc tctttgccaa ctggtacagt aacgggaatg aaattccagt
    56341 tgacaaagat gaggccttga ccttctggaa acaaaaattg tcagatgtgc gtgcctacgc
    56401 ttcgaccaac caatggttga tgatgaacgg ctgtgaccac cagcctgtac agaaaaatct
    56461 gagcgaagcc attcgtgtgg caaatgaact cttcccggat gtaatctttg ttcatagttc
    56521 ctttgatgaa tatgttcaag ctgtagaagg tgcgcttcct gaacacttat caactgttac
    56581 aggtgagttg accagtcagg aaacagatgg ctggtacaca cttgccaaca cttcttcatc
    56641 ccgcatttac ctaaaacaag ccttccaaga aaatagcaac ctcctagagc aagtggtaga
    56701 acccttgact attatcactg gtggacacaa ccacaaggac cagttgacct atgcttggaa
    56761 aacacttttg cagaatgcgc cacatgatag tatctgtggc tgtagcgtgg acgaagttca
    56821 ccgcgagatg gaaacgcgtt ttgccaaggt caaccaagta ggaaactttg ttaaaagtaa
    56881 tttgctcaac gagtggaagg gtaaaattgc tacggataag gctcaaagtg actatctctt
    56941 tactgtcatt aacacaggct tgcatgataa ggtcgatact gtcagcacag tgattgatgt
    57001 ggcgacttgt gatttcaagg aattgcaccc aacagaaggc tacaaaaaga tggctgctct
    57061 tatcttgcca agttaccgtg tggaggactt ggatggtcgt cctgtagagg ctacaatcga
    57121 agacctcgga gctaattttg aatacgattt accaaaagac aagttccgcc aagctcgtat
    57181 tgctcgacaa gtgcgcgtga ccattccagt tcacctagca ccgctttctt ggacaacctt
    57241 ccaattgctg gaaggagaac aagaacaccg tgagggtatt taccaaaacg gagtgattga
    57301 tacaccattc gtaacggtga gtatggatga caacatcaca gtctatgata agacaactca
    57361 cgaagcctat gaagacttta tccgctttga agaccgtggg gacatcggaa acgagtatat
    57421 ctatttccaa ccaaaaggaa cagagccaat ctttgcagag cttaagggcc acgaggtctt
    57481 ggaaaacaca gcttgctatg ctaaaatctt gctcaaacat gaattgaccg tgcctgtcag
    57541 cgcggatgaa aagctagaag aagagcaaca aggtatcatc gagtttatga agcgtgaggc
    57601 tggacggtca gaagaattga caaacattcc tctggaaact gagttgactg tcttcgttga
    57661 caatccacaa atccgcttca agactcgctt tactaacact gccaaggatc accgtatccg
    57721 tctcttggtc aagactcata acacgcgtcc aagtaatgat tctgaaagta tctatgaggt
    57781 ggtgacacga ccaaacaaac cagctgcttc atgggaaaat cctgaaaatc ctcaacacca
    57841 acaagctttt gtcagtctgt atgacgatga aaaaggggtg actgtatcca ataagggatt
    57901 gaatgaatac gaaatccttg gggataacac tattgccgtg accattttgc gtgcatcagg
    57961 tgagctaggt gactggggct acttcccaac gccagaagca caatgcttgc gggagtttga
    58021 agtcgaattt gcgattgaat gccaccaagc ccaagaacgc ttctcagcct atcgtcgtgc
    58081 caaagccttg cagacaccgt ttaccagcct tcagcttgct agacaggaag gaagcgtggt
    58141 tgcgactggt agcctcttga gccattctgt tctcagcata ccgcaagttt gtccaacagc
    58201 ctttaaagtg gcggaaaatg aagaaggcta tgtcctccgt tactataata tgagtcaaga
    58261 aaatgtgcgc atatcagaac atcaacaaac cattcttgac ttacttgagc gaccatatcc
    58321 agttcattca ggactattgg ctccacaaga gattcgtaca gaattcatca aaaaagaaga
    58381 aatttaattt caaaaagtaa acatcaaaag aaaggagggg cgaaaaagta agaactaact
    58441 gctgattcgc ccctttttat ggtaaaaaca atgaccattg caacgattga tatcggaggg
    58501 actgggatta agtttgccag tctgactcct gatgggaaaa tactggataa gacaagtatt
    58561 tcaacgcctg aaaacttgga ggatttacta gcgtggctag atcaacgctt gtcagaacag
    58621 gattacagtg ggattgctat gagtgttcca ggtgcagtca atcaagagac aggtgtgatt
    58681 gatggcttca gtgcggtgcc ctacatccat ggcttttctt ggtatgaggc gcttatctct
    58741 tatcagctac ctgtccattt agaaaatgat gccaactgcg ttggactcag tgaactacta
    58801 gctcatccag agcttgaaaa tgcagcctgt gtcgtgattg ggacagggat tggcggagcc
    58861 atgattatca atggtagact tcatcgaggt cgccacggtc tgggtggaga atttggctac
    58921 atgacaaccc ttgcccctgc tgaaaaactt aataactggt cgcaactagc atcaactggg
    58981 aatatggtac gatacgtgat tgaaaaatct ggtcatactg attgggacgg tcgcaagatt
    59041 taccaagagg ccgcagctgg taatatcctt tgtcaagaag ccattgagcg catgaaccgc
    59101 aatctggcgc aaggcttgct caatatccag tatctgatcg atccagatgt catcagtctg
    59161 ggtggctcta tcagtcaaaa tccagatttt atccaaggtg tcaagaaggc tgttgaagac
    59221 tttgtcgatg cctacgaaga atacacggtc gcaccagtta tccaggcctg cacctatcac
    59281 gcagatgcca atctctacgg tgctcttgtc aactggctac aggaggaaaa gcaatggtaa
    59341 gatttacagg acttagtccc aaacaaacgc aagctattga ggttttaaaa ggtcatattt
    59401 ctctaccaga tgtggaagtg gctgtcactc agtctgacca agcatctatc tctatccagg
    59461 gtgaggaagg tcactatcaa ttgacctacc gcaaacctca ccaactctat cgtgccttat
    59521 ccttgttggt aacagttcta gcagaagctg ataaagtaga gattgaggaa caagcagctt
    59581 acgaagattt ggcttacatg gttgactgtt ctcgaaatgc ggtgctgaat gtggcttctg
    59641 ccaagcagat gattgaggtc ttggctctca tgggctactc aacctttgag ctttacatgg
    59701 aagacactta ccagattgaa gggcaatctt actttggcta tttccgtgga gcttattcag
    59761 cagaggagtt gcaggaaatc gaagcctatg cccaacagtt tgacatgacc tttgtaccat
    59821 gcatccagac cttggcccac ctgtcagcct ttgtcaaatg gggtgtcaag gaagtgcagg
    59881 agctccgtga tgtagaggac attcttctca ttggcgaaga aaaggtttat gacctgattg
    59941 atggcatgtt tgccacgttg tctaaactga agactcgcaa ggtcaatatc gggatggacg
    60001 aagcccactt ggttggtttg ggacgctacc tgattttgaa cggtgttgtg gatcgtagtc
    60061 tcctcatgtg ccaacacttg gagcgcgtgc tggatattgc tgacaaatat ggtttccact
    60121 gccagatgtg gagtgatatg ttcttcaaac tcatgtcagc ggatggccag tacgaccgtg
    60181 atgtggaaat tccagaggaa actcgtgtct acctagaccg tctcaaagac cgtgtgactc
    60241 tggtttactg ggattattat caggatagcg aggaaaaata caaccgtaat ttccgcaatc
    60301 atcacaagat tagccatgac cttgcatttg cagggggagc ttggaagtgg attggcttta
    60361 cacctcacaa ccatttcagc cgtctcatcg ctatcgaggc caataaagcc tgtcgtgcca
    60421 atgacatcaa agaagtcatc gtgacgggtt ggggggataa cggtggggaa acagcccagt
    60481 tctctatcct accaagcttg caaatctggg cagaactcag ctatcgcaat gacctagatg
    60541 gtttgtctgc gcacttcaag accaatactg gtctaacggt tgaggatttt atgcagattg
    60601 accttgccaa cctcttacca gacctaccag gcaatctcag cagtatcaat cccaaccgct
    60661 atgtttttta tcaggatatt ctttgtccga ttcttgatca acacatgaca cctgaacagg
    60721 acaaaccgca cttcgctcag gctgctgaga cgcttgctaa cattaaagaa aaagctggaa
    60781 actatgctta tctctttgaa actcaggccc agttgaatgc tattttaagt agcaaagtag
    60841 atgtgggacg acgcattcgt catgcctacc aagcggatga taaagaaagt ttacaacaaa
    60901 tcgccagaca agaattacca gaacttagaa gccaaattga agacttccat gccctcttta
    60961 gtcaccaatg gctgaaagaa aacaaggtct ttggtttgga tacagttgac atccgtatgg
    61021 gcggactctt gcaacgcatc aaacgagcag aaagccgtat cgaggtttat ctggctggtc
    61081 agcttgaccg catcgacgag ctggaagttg aaatcctacc atttactgac ttctacgcag
    61141 acaaggattt cgcagcaact acagccaacc agtggcatac cattgcgaca gcgtcgacga
    61201 tttatacgac ttaatattct tcgaaaatct cttcaaacca cgtcagcttc catctgcaac
    61261 ctcaaaacag tgttttgagc aacctgcagc tagcttccta gtttgctctt tgattttcat
    61321 tgagtataaa aacaagaaca ccttgcttgg cgcagggtgt ttcgcgtgaa acagaagaat
    61381 tatctggttt caaatgctac agttatacaa acttatgata aaatagcaga aagtgaatgt
    61441 ttcctaagag caattggagg tattatgcta cacttaaaat tagtaaaaca agaaatagaa
    61501 gctgaaaagc cagcatctgt agaagcttgg atcatttccg tcaaatttaa aaaaggttgc
    61561 taccgacata tatagattcc aaaaacaaaa acgttagcgg aactagcaga tgtgatttta
    61621 tggagttttg attttgcaaa tgatcatgct cacgcatttt tcatggataa tgttgagtgg
    61681 agtcatgcag attcttactt tcttagcttt gttagtgacg atgttgaaga acgttacaca
    61741 gaaaatgtct atctggatag cctaagtgtc aaacaaaaat ttaagtttat tttcgacttc
    61801 ggtgatgaat ggcgttttga atgccaagtg ctgagagaaa tcgagacaga ggacgaagaa
    61861 gcttatctcg tacgttcggt tggaacgtcg ccagaacaat atccagatta tgatggtttt
    61921 gactatgaag aatggtaaaa ttgaaatcag tctgtgtagg cttagtattt caatagactt
    61981 cctgcaaaac tagaatccta gttcatgatt gataatacca gcaatcaaat tcattcgtaa
    62041 tccgaagcgt ttacgatgat ttcgataggt tgttgaaatc attttaaacg tttttacttt
    62101 ggcaaagatg ttctcaacct tgcttctctc cttagatagc gcatggttat aggttttatc
    62161 ttcaactgtt agcggcttga gtttgctgga tttacgtgga gtttgtgctt gagaatatat
    62221 cttcatgagc ccttgataac cactgtcagc caagattttt ccagcttgtc cgatatttct
    62281 gcgactcatt ttgaacaact tcatatcatg acaatagttc acagcgatat ccaaagaaa
//
LOCUS       DAVEHY010000008        62083 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVEHY010000008 DAVEHY010000000
VERSION     DAVEHY010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.008"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(2..1168)
                     /locus_tag="VUZ44_000618"
     CDS             complement(2..1168)
                     /locus_tag="VUZ44_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU0319577.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(1176..2270)
                     /locus_tag="VUZ44_000619"
     CDS             complement(1176..2270)
                     /locus_tag="VUZ44_000619"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU0319578.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            complement(2427..2972)
                     /locus_tag="VUZ44_000620"
     CDS             complement(2427..2972)
                     /locus_tag="VUZ44_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319579.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     TDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            complement(3008..3547)
                     /locus_tag="VUZ44_000621"
     CDS             complement(3008..3547)
                     /locus_tag="VUZ44_000621"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319580.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKLLLLDHLDQENQRLCVC"
     gene            complement(3556..4101)
                     /locus_tag="VUZ44_000622"
     CDS             complement(3556..4101)
                     /locus_tag="VUZ44_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319581.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            complement(4273..6231)
                     /locus_tag="VUZ44_000623"
     CDS             complement(4273..6231)
                     /locus_tag="VUZ44_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0319582.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTPKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(6434..8056)
                     /locus_tag="VUZ44_000624"
     CDS             complement(6434..8056)
                     /locus_tag="VUZ44_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU0319583.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            8162..9607
                     /locus_tag="VUZ44_000625"
     CDS             8162..9607
                     /locus_tag="VUZ44_000625"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU0319584.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGTTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(9653..9847)
                     /locus_tag="VUZ44_000626"
     CDS             complement(9653..9847)
                     /locus_tag="VUZ44_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU0319585.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVSKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(9948..10556)
                     /locus_tag="VUZ44_000627"
                     /pseudo
     CDS             complement(9948..10556)
                     /locus_tag="VUZ44_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(10581..11093)
                     /locus_tag="VUZ44_000628"
     CDS             complement(10581..11093)
                     /locus_tag="VUZ44_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU0319586.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(11179..12114)
                     /locus_tag="VUZ44_000629"
     CDS             complement(11179..12114)
                     /locus_tag="VUZ44_000629"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU0319587.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(12185..12484)
                     /locus_tag="VUZ44_000630"
     CDS             complement(12185..12484)
                     /locus_tag="VUZ44_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU0319588.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(12474..13223)
                     /locus_tag="VUZ44_000631"
     CDS             complement(12474..13223)
                     /locus_tag="VUZ44_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU0319589.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(13277..13636)
                     /locus_tag="VUZ44_000632"
     CDS             complement(13277..13636)
                     /locus_tag="VUZ44_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU0319590.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(13638..15038)
                     /locus_tag="VUZ44_000633"
     CDS             complement(13638..15038)
                     /locus_tag="VUZ44_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU0319591.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(15333..15572)
                     /locus_tag="VUZ44_000634"
     CDS             complement(15333..15572)
                     /locus_tag="VUZ44_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU0319592.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(15604..16074)
                     /gene="ssbA"
                     /locus_tag="VUZ44_000635"
     CDS             complement(15604..16074)
                     /gene="ssbA"
                     /locus_tag="VUZ44_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU0319593.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(16086..16376)
                     /locus_tag="VUZ44_000636"
     CDS             complement(16086..16376)
                     /locus_tag="VUZ44_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU0319594.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(16529..17875)
                     /gene="asnS"
                     /locus_tag="VUZ44_000637"
     CDS             complement(16529..17875)
                     /gene="asnS"
                     /locus_tag="VUZ44_000637"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU0319595.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIICATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(18032..18256)
                     /locus_tag="VUZ44_000638"
     CDS             complement(18032..18256)
                     /locus_tag="VUZ44_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU0319596.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            complement(18249..19436)
                     /locus_tag="VUZ44_000639"
     CDS             complement(18249..19436)
                     /locus_tag="VUZ44_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU0319597.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEKRLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(19433..19921)
                     /locus_tag="VUZ44_000640"
     CDS             complement(19433..19921)
                     /locus_tag="VUZ44_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU0319598.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            20242..20790
                     /locus_tag="VUZ44_000641"
     CDS             20242..20790
                     /locus_tag="VUZ44_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU0319599.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            complement(21027..28091)
                     /locus_tag="VUZ44_000642"
     CDS             complement(21027..28091)
                     /locus_tag="VUZ44_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU0319600.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADATEAELSAAESSIQSFIIGLELRSNSNKETVSETPVAKKADAVESKEGAK
                     PAATTERSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKEDVNR
                     GYSGFRAASNPANPIVSGSGNTVAFADISQGGRSYSFRGYGNSRGGNSIHYDVTTVRS
                     GNSVNFTISYSAPGDSREFVNNNFILDKGDGFGNPSNATITSSNPRVREQSKSISQGA
                     NYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGGGGAATSND
                     PYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEK
                     GQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPRVDQNKVGD
                     TNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAKGEKGDRGER
                     GLTGAQGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTGAQGAKGEKGAQGERGLTG
                     AQGAKGEKGAQGERGLTGAQGAKGEKGDQGERGLTGAQGQAGRDGVTPTVTVKDNKND
                     GTHTITINDGRGNVTSTVVRDGFDGASPLVATQRNDADKTTTVIFYYDKNGNNELDAS
                     DKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITI
                     NDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEV
                     VIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDG
                     KTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDG
                     KEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEK
                     GAQGERGLTGAQGVKGEKGEQGERGLTGSKGEKGDQGERGLTGAQGAKGAKGEQGLQG
                     RDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARP
                     GQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNGKNGVLVTITPVGGRPQTTFVED
                     GQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKV
                     NPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERG
                     LTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNW
                     DKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDDHSTDITFTVPGKDPVTVNVKDGENG
                     LNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGAD
                     GRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEA
                     GHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQDGQTPTITTQRGQDGQSTVVTIT
                     TPGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRATDAAATPTRNGIRVTVYDD
                     VNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTT
                     VVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDG
                     THTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNG
                     RDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKIS
                     VLNGDGTTTETIITDGKSPVATVRDNQDGTYTIRVENGNGTVSETTVRDGKSPTAKVV
                     DNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGADGKGTTTTIF
                     DGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPTVTVKNNNDGTHV
                     VTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVTKTVIKDGKDG
                     RDGRDGRDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVPAQPTPNVPT
                     PEVPVKPVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPV
                     NANPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            28307..29791
                     /locus_tag="VUZ44_000643"
     CDS             28307..29791
                     /locus_tag="VUZ44_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0319601.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILEGLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            complement(29842..30570)
                     /gene="yaaA"
                     /locus_tag="VUZ44_000644"
     CDS             complement(29842..30570)
                     /gene="yaaA"
                     /locus_tag="VUZ44_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU0319602.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(30649..30813)
                     /locus_tag="VUZ44_000645"
     CDS             complement(30649..30813)
                     /locus_tag="VUZ44_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU0319603.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            complement(30992..32587)
                     /locus_tag="VUZ44_000646"
     CDS             complement(30992..32587)
                     /locus_tag="VUZ44_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319604.1"
                     /translation="MKRIVCELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(32599..33009)
                     /locus_tag="VUZ44_000647"
     CDS             complement(32599..33009)
                     /locus_tag="VUZ44_000647"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU0319605.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETTRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(33125..33916)
                     /gene="yghU"
                     /locus_tag="VUZ44_000648"
     CDS             complement(33125..33916)
                     /gene="yghU"
                     /locus_tag="VUZ44_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU0319606.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(33929..36625)
                     /locus_tag="VUZ44_000649"
     CDS             complement(33929..36625)
                     /locus_tag="VUZ44_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU0319607.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            36929..38113
                     /gene="mntE"
                     /locus_tag="VUZ44_000650"
     CDS             36929..38113
                     /gene="mntE"
                     /locus_tag="VUZ44_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU0319608.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(38256..40127)
                     /locus_tag="VUZ44_000651"
     CDS             complement(38256..40127)
                     /locus_tag="VUZ44_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU0319609.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMVNQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(40124..41308)
                     /locus_tag="VUZ44_000652"
     CDS             complement(40124..41308)
                     /locus_tag="VUZ44_000652"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU0319610.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(41320..42087)
                     /locus_tag="VUZ44_000653"
     CDS             complement(41320..42087)
                     /locus_tag="VUZ44_000653"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU0319611.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(42353..43201)
                     /locus_tag="VUZ44_000654"
     CDS             complement(42353..43201)
                     /locus_tag="VUZ44_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU0319612.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(43203..43577)
                     /locus_tag="VUZ44_000655"
     CDS             complement(43203..43577)
                     /locus_tag="VUZ44_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU0319613.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(43651..45003)
                     /locus_tag="VUZ44_000656"
     CDS             complement(43651..45003)
                     /locus_tag="VUZ44_000656"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU0319614.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(45027..45806)
                     /locus_tag="VUZ44_000657"
     CDS             complement(45027..45806)
                     /locus_tag="VUZ44_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319615.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEASITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(45793..46650)
                     /locus_tag="VUZ44_000658"
     CDS             complement(45793..46650)
                     /locus_tag="VUZ44_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU0319616.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            46786..47754
                     /locus_tag="VUZ44_000659"
     CDS             46786..47754
                     /locus_tag="VUZ44_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU0319617.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNEKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(47787..48698)
                     /gene="whiA"
                     /locus_tag="VUZ44_000660"
     CDS             complement(47787..48698)
                     /gene="whiA"
                     /locus_tag="VUZ44_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU0319618.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(48695..49672)
                     /locus_tag="VUZ44_000661"
     CDS             complement(48695..49672)
                     /locus_tag="VUZ44_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU0319619.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(49669..50559)
                     /gene="rapZ"
                     /locus_tag="VUZ44_000662"
     CDS             complement(49669..50559)
                     /gene="rapZ"
                     /locus_tag="VUZ44_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU0319620.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(50611..50991)
                     /locus_tag="VUZ44_000663"
     CDS             complement(50611..50991)
                     /locus_tag="VUZ44_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU0319621.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(51002..51589)
                     /locus_tag="VUZ44_000664"
     CDS             complement(51002..51589)
                     /locus_tag="VUZ44_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU0319622.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(51598..52830)
                     /gene="clpX"
                     /locus_tag="VUZ44_000665"
     CDS             complement(51598..52830)
                     /gene="clpX"
                     /locus_tag="VUZ44_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU0319623.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(52862..53032)
                     /locus_tag="VUZ44_000666"
     CDS             complement(52862..53032)
                     /locus_tag="VUZ44_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319624.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(53032..53538)
                     /locus_tag="VUZ44_000667"
     CDS             complement(53032..53538)
                     /locus_tag="VUZ44_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU0319625.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFGPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(53668..54186)
                     /locus_tag="VUZ44_000668"
     CDS             complement(53668..54186)
                     /locus_tag="VUZ44_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU0319626.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(54683..56188)
                     /gene="lytC"
                     /locus_tag="VUZ44_000669"
     CDS             complement(54683..56188)
                     /gene="lytC"
                     /locus_tag="VUZ44_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU0319627.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGTRYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            complement(56226..56984)
                     /locus_tag="VUZ44_000670"
     CDS             complement(56226..56984)
                     /locus_tag="VUZ44_000670"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU0319628.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(57082..57759)
                     /locus_tag="VUZ44_000671"
     CDS             complement(57082..57759)
                     /locus_tag="VUZ44_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU0319629.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELFFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(57768..58712)
                     /locus_tag="VUZ44_000672"
     CDS             complement(57768..58712)
                     /locus_tag="VUZ44_000672"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU0319630.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(58894..59406)
                     /locus_tag="VUZ44_000673"
     CDS             complement(58894..59406)
                     /locus_tag="VUZ44_000673"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU0319631.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(59493..60251)
                     /locus_tag="VUZ44_000674"
     CDS             complement(59493..60251)
                     /locus_tag="VUZ44_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU0319632.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKFAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            60459..60605
                     /locus_tag="VUZ44_000675"
     CDS             60459..60605
                     /locus_tag="VUZ44_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319633.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            complement(60752..61882)
                     /gene="ugpC"
                     /locus_tag="VUZ44_000676"
     CDS             complement(60752..61882)
                     /gene="ugpC"
                     /locus_tag="VUZ44_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU0319634.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
BASE COUNT        17587 a        14094 c        11432 g        18970 t
ORIGIN      
        1 tttaacgttt ggcaaaagta gccacaatcc gctgacagac ttcttgcaac agagatttgg
       61 gcatagctat attgatgcgg gcatggagac ttccttcctc tccaaaatcc aaaccacggt
      121 tgaggataac cttggcttca tttctcaaca actcttgcaa tgtttcatca gtcaggtcat
      181 aagctgaaaa gtcaagccaa atcaagtagg taccttgcgg tttcatgacc ttgattttag
      241 tctcttttcc aaacagatcc accacataat tgatgtggtc ttcaaagact tgcttgagtt
      301 cctctagcca atctttaccg tatcgatagg cagcttctgt cgccaaataa cccaagcctg
      361 aaatttcatg ctgattattg gccaacaggc gtttctggaa agctagtctc aacttaggat
      421 tttcaatgac tgcataggaa ttttttgttc cagcaatatt aaatgtttta gtggcactgc
      481 tcaagacgat agcaaaattt ttgaaggcag gattgatggt attgaaagac tggtgtttgt
      541 gaccaaagag ggtcaaatct tggtgaatct catccgaaac taacaaaaca ccgtgttttt
      601 ggcagagttg gccaatcttc tccaacactt ctttttccca aacacgtcca ccaggattgt
      661 gagggttgca aagaatatag agtttaacct cctcttccac caaatccttt tcaagttggt
      721 caaagtcaat ctcaaacaga ccatcctttt ccactaagga attagtaatc aatctacgat
      781 tattcaactt gacactgcga gcaaagggtg ggtagacagg cgtgttaatt aaaaccgcct
      841 cgccttcttt tgtaaaggtt tgaatagctg ttgagatggc tggtaccaca ccctcgataa
      901 agacaagagc ctctttgtca aagttgtaac cgtattgtgt agcttcccac ttttgaactt
      961 ccttaattaa gtcttcactg gcataggtat aaccataaac cagttggtct gcgtaagttt
     1021 gcacggcttg gcggatttca ggcaagacca caaagtccat atccgctatc caagctggta
     1081 gaacttcact atccgtttct gtttctttcc atttataggt atggtgccct aaacggttgg
     1141 gcaggcttgt aaaatcatat tttcccatct ttgtcttatc cttctatggc ttggcgcaaa
     1201 tctgcaatca aatctctagc atcctcaatc ccaatagaca aacgcaagag gtcatctgtc
     1261 aaaccataag aatggcgtac ctctgctgga atatcagcat gagtttgagt cgttggataa
     1321 gtaataagac tttccactcc acccaaactt tccgcaaaag agaagacctt gagactgttc
     1381 aaaatatgag gaatgcgtgt ttcatcggct actttaaagg aaatcatgcc tccacgacca
     1441 gtgtagagaa cttccttaac tgctggagaa tccttcaaaa aggcaaccac ttcttgggcg
     1501 ttagctgttg agcgctccat acgaagagac aaggtcttga gaccacgaag caactggtag
     1561 ctgtcaaatg gagacaagac tgcccctgtt gtattaagat tgtaaaaaag cttctcgtat
     1621 agttctaaac tattggtcac aaccactcca gccaagacat cattgtggcc tgctagatac
     1681 ttggttgctg aatggagaac gatatctgct ccatcttcaa tcggacgttg gtagataggg
     1741 ctatagaagg tattgtccac caccactttg gcacccttag catgagccaa ttttgctagt
     1801 ttttcgatat caaattccaa catcaaggga ttggttgggg tttcgatata gagaacatcc
     1861 acatcctttt ctaactcggc aatcaactct tcttctgtat tggcataggt aaaatggaaa
     1921 cgaccttcct gctccacttg gttaaaccag cgaaaagaac cgccgtaaag atcacgcact
     1981 gccaagacct tacttcctac tggaaagccg ctaaaggcca gtacaatagc tgacatccct
     2041 gagctagtcg ctaaggcata gtctgctgac tcaatagtcg ccaagacttc ctcagcctta
     2101 ctacgagttg gatttttagt gcgcgtatag tcaaacccag tagatcgacc aaactctgga
     2161 tgctgatagg tcgttgaaaa atgaagcggt gtcaccaatg cacctgtcgc ttcatctgac
     2221 ttaatacccg cctgggccaa aattgtgtta atgtgtaatt ccttgctcat acaatacctc
     2281 caaatctata gtaactattg taccacttat tttcatcaac tcattttctt cttttcaaga
     2341 gctagttata gtttcaaact atataaaaag ggagtttttc ctgctccctt taatagacta
     2401 taaaatggtg aatctcaaaa gacacttcac tctatcattt gctcctgcac aaaacgagca
     2461 taacgctcat gattttccag tagttcctta tgagttcctg agccagtgat tttcccctcc
     2521 tctaagaaga aaatacaatc cacatctttt accgttgaca aactatgcgc tataatcaca
     2581 accgtcttct cctttaatac agaatagagg ctactgataa tcgcatactc agaatccgca
     2641 tcaagattag cagtagcttc atcaaatata agaatttcag catcttttaa gtaggttcta
     2701 gctatttgaa gtctttggct ttgcccccct gacaagaatc gtccgcgttc accaacttca
     2761 gtatctagtc cctctttcat ggagcgaatc tcatcaccta gtgatactaa gtctagcact
     2821 ttcatcaatt catcatcagt tactaagcga ttcaaaccga gacaaagatt gtcacgaata
     2881 ctgccagata agactgcatt attttgtgaa acccaagcga ttttacttct ccattctttt
     2941 aagttaaaat catatatact tgattgctcc attagaatat ctcctgaaag cggtttataa
     3001 aaccgctcta acaaacgcac aatcgttgat tttcctgatc cagatggtcc aacaaaagca
     3061 atttttgccc cttgaaaatt gaacaagtaa tatcctttaa gacaggtcga ttttcatcat
     3121 aaccaaaata gacatggtta aaattcaacc cttgtcctga taccgatttt cctccctcaa
     3181 atttttcttt aggaactgca agcaagttat ccagtgcaac tgaagatccc ttgctcctag
     3241 aataaacagt tacaaaatta gctatattac taataggatt aagtaattga aagaggtaaa
     3301 tcaaaaacga aaccaaggtt cccacagata tatatcctgc gctgacccga taacccccat
     3361 aggttagcat cacagctata gtcgcaaaga taaataagag agcaaacggg gtctcaaaag
     3421 aagtaaccct atctgatttc agtgaattgt tttgtaccct ttcaatacaa ttatccaaaa
     3481 catcctgtac acttttctct gcttggttag tcttaattaa ttcatgttct tgaatctttt
     3541 cagtcaattg ccctgttaaa tttcctcctg taaacgacga ctatactttt cactgatatt
     3601 ggaaaggggc aagataataa acatcataca aggaagagtg atgaataaaa gtagagaaag
     3661 attccaatca agactaaata agactacaat ggaaccaagt accataacta aactcagaat
     3721 aatatttggg aaagtcgtaa ttaaaaactc acgaatgaca ctcatgtcat tgacaatggc
     3781 agaagtcaac tccccacttt ggctcttatc aaagaaggat ttctctgcat aaatcaaccc
     3841 ctctatcact tttttcctga tttttgctat ctttttttca cccgattgac taaacagata
     3901 gtaaccaata gaagaaaaca aggcttgacc aataaaaatc aaaaacgatt gaaatacttt
     3961 ggaacctata ttttcaatag aactcccatc tattaaaccc tttaagataa ggggaagcaa
     4021 caaagcaagt agactagaca gaacaagtaa gaaactcccc ataatcacct tagtatctac
     4081 tcttaataat tttaatttca taaatactcc ttataatatt tcaacggata aagtcgggaa
     4141 taactcaatt tgaggataaa atctaataaa tcttcctata acaaaacgca taacatctag
     4201 gattttatat acctgatatt atgcgttttt aagcacaaag acttcttaca caaacttatc
     4261 tacaattaga ttttatttga catgttttgc caattcttct tgggcttttt tattggattc
     4321 ttctttttct ttcaaccatt tttctctggc ttttgcatat tcgtctgttg tgacaatctt
     4381 atcttgtact ttgaggtatt tatatgattc aacccctttt gtaccggtta aaccataggc
     4441 agcagcaaat ggtacggttc ttctcaatga tggtgttccc ccacgcgaaa cacttggaag
     4501 aactaaagaa ctatcaatca accaagcttg aatatcagca tatttctcat aacgtttggc
     4561 tggatcttgc tctttattag cttcttccaa catttgagta tagacatcca gtccaactgc
     4621 cttagccttg tcattggctt ctccaggctc tagtccaaga ttttgtagaa ctcctccact
     4681 attagtatta aaaatatcga gataggttga cgggtcttga taatcaggtc cccaaccgcc
     4741 atgatataaa tcatagtctt tctgagcagc tgtttgagca aagtagcctg aactgtcaaa
     4801 ctcatctgat gttaattgct gaatgtcaat cactacatta tcagaaccta aaacagattc
     4861 aattgattgt ttgatagaac taactccttg tatgcctact ttatctgtta cttccacagt
     4921 cttatccaag tggattggga attgaacacc ctttgcttcg agttctttct tagcttccgc
     4981 aaacttagcc ttggctttct caggattgta ataagggtct tgaccatccg caaagttgat
     5041 accttgccat tccttaccat agttgaccat cttagaggct acaacttcac caaagtcttt
     5101 tcccttgata ctgacaaagt ttggaggaac cactaggtta cgcaaaatct ttgttgcacc
     5161 ttctttccct tcagactgag ccccataaga tgttctgtca aaagcaaaat tgatagcctg
     5221 acggaagttt ttattgagaa ctgcttcctg ggtcgatttc ttttcaatgt cacttgtttt
     5281 aggagtataa ttgtaagact tcctatctag gttaaaatta aagaaatatg aagttgaatt
     5341 ttgcatacta tagatgatat tgtttttgta tttttcttta atcccttcat agctggagct
     5401 gttaggaaaa agacgagccg tagtataagc accagctgta aaattacgtt ccagtgattc
     5461 ttggtcgcta ccatcatagt aggtcaattt cacatcgtct acaaagacat tcttagcatc
     5521 ccagtaatta gggtttttct tatattcaat agcagatttt gagacaagtg ctttcatcaa
     5581 gaaaggtcca ttgtacaaaa tactagatgg atccgccttc ccaaaatcat ccccttttga
     5641 tttcaggaaa tctgcattaa caggaaaaag tatcgttgca agtgtttttg aattccagta
     5701 aagttctggt ttaaccaaag tatattgaac cgtttggtca tcaagtgcct tgacaccgac
     5761 agttgaaaag tcgcttgttt taccagtgat atagtcatcc aaaccagcaa cagagtcctg
     5821 cactagatac aaagcttctg attttttatc agctgcatat tgcaaacctg tcacaaaatc
     5881 ctgggcagtt acaggcgcat attcttctcc ctcagaagta aaccacttgg catccttacg
     5941 aagtttgtag gtataggtca aaccgtcctg agaaacagtc caatcctctg ctaatgatgg
     6001 aataatattc ccatattggt cattttctaa taacccgtct accaaatttg caacaatatc
     6061 ggatgttgct gcgcggtttt ctgctagata gttcaaacta gatggatcac ttgaataaac
     6121 atagttatag gtttttgatg cagtgctaga atttccacac gcgctcaata aaactcctgt
     6181 acccaggaca agacctgcca aggttagata tttgctctta gactttttca tttccagaac
     6241 ctcctgcttt aaatatttgt tttattatac aactcttggt ttgtttagtc aattgttttt
     6301 tccaaaaaat caaaaaaacc tcattttcta tttttgaaag ataattttag ctattttgac
     6361 gctaaaaaag gaataagttt caagttctcc taaaagattg ttcaacttat tccttttatt
     6421 tataaatgct accttacgaa agcttaaatt ttgctcgcag gcgatctgct tgggcttttc
     6481 ctattacctt atctaataaa taggtacgca gactcataac catataaagt ccacccccca
     6541 tggcaccgac aagagctaca taaaagaagc tccacaaacg tccacttggt tggaagaaaa
     6601 atcctaacag ccactggatg gttcctatta acagaaacat gactagggtc agcaaactga
     6661 ttaaaatggt tcgcttcaaa atcaccttgc gcttgacacc agttacttta caaatatccc
     6721 gatacatcaa gacgttagga atgatgagag caatggttgt tgaaatcaaa ggaccataac
     6781 tgtggaagag ggcgatggta ggtagttgca agactagctt ggcaatagaa ccatagataa
     6841 aatagagaac ggccttgcgg ttgcggaaca tggcctgaag cattggagac aagaccatgt
     6901 acaagcctaa aataatagac tgcaaaactg caaagacaaa taagcccaga gccaaactat
     6961 ctggcttacc atagaagacc gtataaagag gttctcctac cataaccact ccaaccgttg
     7021 ctggtagcaa gaacataaag agtagggtga gactgtcctg aacgagacga gaagctgctt
     7081 tcaagtcccc cttgacatag ttttccgtca aaagtggcaa accaacactc ccaatcgaaa
     7141 cccctacaga aatcaaaatc atcgtgattt tattaggatt ggctgagaaa taagaaaaca
     7201 tgacaaccaa gtcctcattg ctgtagttgg taaaccagct catactattg ataaaggtca
     7261 gctgatccaa aatctggaag agctggatgg cagaccctgt caggataaaa ggaatggctt
     7321 ccttaatggt atcaaccaag agacgcttac tgttaatctt atctcctgtt tcaaagactc
     7381 ttttgagtga accttcttgg gcaaggaaat aaatcaagac tgcaaaactg gctaccatac
     7441 cgacaaaggc agcaaaggtt gattgggtaa cggctgctag ataatctcct gaaccgagct
     7501 tcataatgat aaaggttgct aggagcatcc agataacacg aatgacctgc tcagcaattt
     7561 ggctcatggc atagggtttg aggttattca tcccttggaa aaatcctcgg ataacactca
     7621 tagacgggaa aatcaagact ccccaagcca agctttgcat gattgggatc aagtctttgc
     7681 ccacgccaga caagtctgct agccaaggag caaagacata caagactaaa gcaaaaacca
     7741 ggcctagtcc tgtcataaag cctaagaagc tccgaatcag ggcaaagcta tgctcttctt
     7801 ctcgcatggt attatacttg gcaacttgct tggccaccgc aactggaatc cccgctgttg
     7861 aaaccaacaa gaaccaagca tagatattgt aacccatggt aaagagacca tttgccttag
     7921 ctgcataagc ccccatccag atgtaccaag ggataatgta aacagccccg agtaggcgac
     7981 tgataaagtt actagccgtt agccaagcag tcccccgtaa catctgggcc tgctggtgat
     8041 tgttttcgtg cgacatagat tcctcattca attttgataa ctaggaaaaa ctccttatct
     8101 tccattataa acttttcctt gttacttgta aatttgcgac tttcggttta caatagaaag
     8161 tatgataaaa attgaaactg tattagatat tttaaagaaa gatggccttt ttcgcgaaat
     8221 tattgaccaa ggtcattacc actacaacta cagcaaagtt gtttttgata gcatcagcta
     8281 cgacagccga aaagtaacag aagacactct tttttttgca aaaggcgctg cctttaaaaa
     8341 agaatacctt ctttctgcta taacacaagg cttagcttgg tatatagctg aaaaggacta
     8401 cgaagtcggt atccctgtca tcattgtgaa cgatataaag aaagccatga gtttgattgc
     8461 catggagttc tatggtaatc cacaggaaaa actcaaactc cttgccttta ctggtactaa
     8521 gggtaagaca acagcagcct atttcgccta taacatctta tctcaagggc atcgacctgc
     8581 tatgttgtcg accatgaaca caactcttga tggagagact ttctttaagt cagcgttgac
     8641 aacccctgag agtattgacc tctttgacat gatgaatcag gctgtgcaaa atgaccgtac
     8701 ccacctcatc atggaagtct ccagtcaagc ctatctggtc aaacgtgtct atggtctaac
     8761 ctttgatgtg ggagttttcc taaatatcag cctagaccat atcggcccga ttgaacaccc
     8821 tagctttgaa gactatttct accacaagcg tctcttgatg gaaaatagcc gagcagtcat
     8881 cattaacagt gacatggacc acttctcagt cttgaaagaa caggttgaag atcaagacca
     8941 tgatttctat ggtagccaat ttgataacca aatcgagaat tccaaagcct ttagattttc
     9001 agctacgggt aaactcgctg gagattatga tatccaactc attggcaact tcaaccaaga
     9061 aaatgcagtt gctgctggac ttgcttgtct ccgtctcgga gcaagtcttg aggacatcaa
     9121 aaaaggcatc gctgcaaccc gcgttcctgg tcgtatggaa gtcctcactc agaaaaatgg
     9181 agccaaggta ttcatcgact atgcccacaa tggggatagt ctgaaaaaac tcatcaatgt
     9241 ggttgaaact catcaaaccg gaaagattgc tctggttctg ggaacaacag gaaacaaggg
     9301 agaaagtcgt cgtaaggact ttggcctcct cctcaatcaa caccctgaga ttcaagtctt
     9361 tctgactgct gatgacccta actatgaaga cccaatggcc attgcagatg aaattagtag
     9421 ctacatcaat catcctgttg agaagattgc ggatcgccaa gaagccatca aggcggcaat
     9481 ggctatcaca aatcacgaat tagatgcagt tattattgcg ggtaagggag ccgattgtta
     9541 ccaaatcatc cagggcaaga aagaatccta cccaggagat acagccgtcg cagaaaatta
     9601 tttataagaa tagaaaaaat caagggaaaa tgaaaccctt gattttttcc tattatttag
     9661 taaaaacgtt tttcaaacct tcaacggcac cttctacagc accttttgcg tcttctacaa
     9721 cgtcttttgc cttagaaact gttttttcaa cagctccttc aagttctgtc ttgctgtctc
     9781 cagtaacttt accaaaacct tctttgacag cgcctgttgc ttgttccaat ttgttttcaa
     9841 gtgacatatg attgtctcct ttagtttatt ccgatatgtg ttaccggtta catatagttt
     9901 ataccgaata ctaaggaaag tcaaacaatg tactcagaaa caagaaatca cgctaagtag
     9961 aaagttaacc tctccttatc aaaatcgata gccaactcat actttccatc ttcattttgc
    10021 acaatatagc ctaagacaac ctaactgtcc acaaagatat cacggcattt ctgcataagc
    10081 tggtcttttt tgagaaattt caacaaaaaa gccgtcatat acttgagggc atactcagga
    10141 ttaacatctc ctaaaatgtc atagagctcc tgctgttttt ctgtcaaagg atactgctgt
    10201 ttgaccttgt aaaaataatt ggacagggtc attttaatgc gcgcaaagtc cgtcttttca
    10261 actaaaatag ctgcattgat ttgattgcgc aattccgtct caaaactctg ctccaacaag
    10321 gcttgataga ccggactagc ttctctgaca aaaatctctt gatccagttc aagactatca
    10381 agtgattcaa gcgtaggaaa attgaggtaa tagcgcttat tttcacgtag aatcaagcct
    10441 gcctttatat actcttccat gagtttatca actgcaacat ctggaaattg agccttaatt
    10501 tcccgtagaa tcacatcctc atactgatcc agatagcgga tcaattctcc aaaaatggct
    10561 gtctcgtcaa acgagatgga ttaaaaatct gaatcatgaa gattcctttc tttacattgt
    10621 aacagaggcg atgctgccaa ctgactagga ttggtaccag cttggttcag aggaacaggc
    10681 agacctagtt ctatgtaata ctccctccaa aaatcactaa tctcctgctc cccatctcca
    10741 aatttcatag gaatagtttc aaaaataggt aggatttctg ctatatactg ggagcagtaa
    10801 aaaccagctg catctggata gaaagaagca ttgtagggtg ctccaagatg tttgcaagct
    10861 ctttccttca ccgactggat atccatttct gggtaaacat agaggtcgta taaatgattg
    10921 gactcaaaga agtctgccgg ttcttgacag acaacaccag cctgtccact agcatgataa
    10981 atcatcccat ccaaataaat ggcaacatgg ctatagttac ctgtggaagt ctggatggcc
    11041 tgtcccatgt ctgacccatc tctcacaaaa atcaaatcgc cattttctaa catacttcac
    11101 tcctagaaaa aaggagccga aactcctttc gatataaggc aaactagact ttccgatttt
    11161 gagctgacac ccaaaatctt acgcattaaa gctttcagtc aattgaggta ccacttgttt
    11221 cttacgtgaa acggcaccag caaggaaggc atgattgttt tcaagtttga agttgaaagc
    11281 cgcttcgacc ttgtccatat tggcaccaag agccaagatt tctgagtttg agttgacgat
    11341 atctgtaatc atcaagacaa agtcagagta gccgtttgat tcgttggcag cttgcattgc
    11401 agcttcaatt tctgcttggc gttccaaaac ttcagcgatg tcaactgtgt tcacttgggc
    11461 aacacggaca ttatttccgt tgagttcaaa agtcttagca tcgatatcaa tcaattcttc
    11521 agcagatttg ctagccaagt tggtaccagc tttcaacatt gccaaaccat attcttccaa
    11581 gttcacacca gccaattcag ccaattcagg agcaatgatt ttatctgttg ggtgtgttgt
    11641 tggtgatttc aaaagaaggg tatctgaaat caaacctgaa agcatcaaac ctgcaatctc
    11701 tttaggcaca gctacaccat gttctttgaa catacggtaa acgattgaag acgctgatcc
    11761 aactggctcc aaacgcatgt aaagtgggct tgcagtttca aagttagcca cacggtggtg
    11821 gtctacaaca ccgtaaactt ctacttcagc gatatctgat acagattgtt ggaattcatt
    11881 gtggtcagtc aagataactt gctctgcccc ctctgctttg gcagaagtga taacacgtgg
    11941 tgcttccaca ccaaaatagt tcaagacaaa ggctgtttct tcatttggag ttccaagggc
    12001 aacagcttcc gtatccaaac cgtaagcttc ttttgcaagg taggcaaaag ctacagatga
    12061 tccgatggca tctgagtctg gattttggtg accaaatact agaatcttgg acatgataat
    12121 acctcatttt gtttattttc tttattgtag catttttttc gctttttgac aaaggtaaga
    12181 ggagtcaaag gactccccac gattcttcaa aataactgag taaatttcta tcttgatttt
    12241 cagataaaaa ttcttccttc tgtggcctct tcttacgctt gagaagagct tcagccgaca
    12301 tggcttcttc cttactggca aaaccttgag catagataag tttgactggc aagcgtgctc
    12361 gtgtatattt ggctcccttc ccactattgt ggatagcgag gcgtcttctc atatcagtcg
    12421 tatagcctat atagtaggat ccatcacgac actccagaac gtacatataa gccttatgat
    12481 ccataataaa tctcttcgat ttcgggcgta taagagccat catcattgtg gacaatcaaa
    12541 ggaggtaaga ccttaaagcc acttgttgag ccatccttga tcgcctcaat caaaagcata
    12601 ttggcttcct tttctctttt tggataaaca aactgcaggc gcttaggggc tagattatgt
    12661 cgttttaacg tatccaaaat atccagaagt cgatcaggac gatgaaccat ggccaaacgc
    12721 ccattagact tgagaatact ctgggcacta cgacagattt cttccaaatt agtcgtgatt
    12781 tcgtgtcgag ccaagagata atgttcactc tcgttcagat tagaataagg atccaccttg
    12841 aaatagggtg gattacacaa aatcatatcc accttactcc cctgaatgtg agcaggcata
    12901 tttttcaaat catcgcagat gacctgcatt tgctcctcta atccattcaa acggacagag
    12961 cgttcagcca tatccgccaa acgctcctga atctcaacag acaatatctg tgcttgagta
    13021 cgagtgctag caaaaagccc cactgctcca ttcccagcac agaaatccac aatcaacccc
    13081 ttcttaggaa aacgtggaaa tcgtgataag agaacactat ccaccgaata gctaaaaacc
    13141 tctctatttt gaatgatttt gatatctgtc gaaaagagct ggttaatgcg ctctcctgat
    13201 tttaataatt gttcttcttc catggtccta ttatagcaaa ttcatattaa cattacaaaa
    13261 aatataaaac tctaaactac ttcttctttt ttaaatggtg cagggcttct ccagtccaga
    13321 ttggtagcat tcgtcgaaag ggagcaaaac cgtagttaaa gcggtcgctt gaaaagcgtc
    13381 tccgtctagg aaactggtac ttttcttcct ccaaagtgcg gatagaaaga ctggctttcc
    13441 ccgtaaattc atctaaatcc actacctgaa cttgaacctc ttcatcgact ttcaaggttt
    13501 catgaatatt ttcaataaat cctgtccgaa tttctgaaat gtgaatcagc cccgtatcac
    13561 ccgtctctaa ctcaacaaag gcaccgtagg gctgaatccc tgtaatacgc ccctttagct
    13621 tatcaccgat tttcatctta gtcctcgatt tcaatagttt caattacaac atcttcaact
    13681 ggcttgtcca tagctcctgt ctcaacagca gcaatggcat ccaagacagc gtaagatgct
    13741 tcatcagcta actgaccaaa aaccgtgtga cggcggtcta ggtgaggtgt cccaccttga
    13801 ttggcataga tttctgcaat cggttctggc caaccaccac gagtaatttc tttcttagaa
    13861 taaggtaggt gttggttttg cacgataaag aactggctgc cgttggtatt tggaccagca
    13921 tttgccatgg aaagagcacc acggatattg taaagctctt ctgagaattc atcctcaaaa
    13981 gattcgccgt agattgactg gccacccata ccagttccag ttgggtctcc accttggatc
    14041 ataaagtcct tgataatacg gtggaaaatg acaccatcat agtagccatc ttttgaaaga
    14101 gatacaaagt tagccactgt tttaggagca tgttcaggga aaagcttgat acgtaagtct
    14161 ccgtgattgg tcttaatagt cgcaagagga ccttctactg tttcaatgtc tacttgtgga
    14221 aaatgcaatt ctttttctac cataccaaat acttctaagg cagcaaaaat gccatcttct
    14281 tctaatgttt ttgtaatata atctgctttt tctttgattt tatcatgaga aattcccatg
    14341 gcaacgctga ttccagcata atcaaagagt tccaagtcgt tgagaccatc tccaaaaacc
    14401 atgaccttct ctggtttcaa gccaaggtgt tccacaacct tttccacccc cgtcgctttg
    14461 gagcctgaaa tcggcacaat atcagacgaa tgttgatgcc aacgaaccat acgaagtttg
    14521 tctgagagac tgtcaggcaa gtgcaagtca tctcccttat cttcaaaagt ccacatctga
    14581 tagatatctt ctttttcatg gaaatcggga tctacatcta agtcgggata aattggattg
    14641 atagcttcac tcatcatatc ggtgcgagtc gacaacttgg catcatgact cccaaccaag
    14701 ccatactcaa ttccttcttg cttagcccaa gagatatact cctcaacatc tgacttttca
    14761 atctgatgct gataaatgac ctgacctttt ttatcttcga tataagcccc attcaaagtt
    14821 acaaaaaagt caggcttgag atcacgaatc tctggaacaa caccaaaaat gccacgtcca
    14881 gaggcgattc ctgttaaaat tcctttttca cgcaactgtt taaaaacagt ggggattgta
    14941 gttggaataa accctgtctt tgaattccgc aatgtatcat caatatcaaa aaagacaatc
    15001 ttgatcttct ttgccttgta tcttaatttc gcgtccatct cactacctct ttcaatctaa
    15061 ctctttccat tatatcataa agtaggcaaa tcccctattt tcaaaaagtt tatcattttt
    15121 attttaattt cttggatgag aaaagagaca tatttatgaa aaagctccat cgtgctttta
    15181 atgtgttctc ttgttttcaa actcgtaaaa agggagccac tgagcctaac tcgctctctc
    15241 atttcaaagc ttgtgaaaaa agacccgttg gggtcttaat tcgctttctt gttttcaagc
    15301 tcatgaaaaa gagacccaac cgggtctttt ctttaatctt cgtttacgaa aggcatcaaa
    15361 gccattacgc gagcgcgttt gatagctgtt gttactttac gttggttttt agctgaagtt
    15421 cctgttacac gacgaggaag gattttccca cgttctgaaa cgaaacggct aagaagctca
    15481 gtatctttgt aatcaacata ttcaattttg tttgctgcga tgtaatcaac ttttttacgg
    15541 cgtttgaatc cgccacgacg ttgttgagcc atgttttttc tcctttataa gtttagttgt
    15601 ccattagaat ggtaaatcat catctgaaat atccaatggg tttgttgctc caaatggatt
    15661 ttcattacgt gaaaagtctg gtactgaatt tgtaggtgct gaatagtttg cagttggtgc
    15721 agagtaagct ccacctgtgt gaccctcacg cacactacgg ctttccaaca tttggaaatt
    15781 ctcagccacg acctctgtca cgtagacacg ttgtccttgc tggttatcgt aactacgagt
    15841 ctggatacga cctgtcaccc cgataagtga gcctttttta gcccagttag caagattttc
    15901 agcctgttgg cgccacataa cgacattgat aaaatcagcc tcacgttcac cattttgact
    15961 cttaaatgta cggtttactg caagagtaaa agtcgcaact gctacatttg atggggtata
    16021 acgcaactca gcgtcacgtg tcatacgccc tacaagtaca acattgttaa tcatagttta
    16081 ccttcttacg cgtcaatttt gacgatcatg tgacgaagaa tgtcagcgtt gatttttgaa
    16141 agacggtcaa actctttaag agctgcatcg tcatttgctt caacgttaac gatgtggtaa
    16201 agtccttcac ggaaatcttg gatttcgtat gcaagacgac gtttttccca agtttttgat
    16261 tcaacaacag ttgcaccgtt gtcagtcaaa atagagtcaa aacgtgctac caaagcgttt
    16321 ttagcttctt cttcaatgtt tggacgaatg atataaagaa tttcgtattt agccattgat
    16381 atgttcctcc ttttggtcta atgaccccaa gactttgcaa ggggtaagtg aggttcgctc
    16441 acaataaact attatactag aaaaaatttt tttacgcaag taaaaacact agaattcgaa
    16501 aaaacgccac atgggcgttt tcctgttctt atggtttgat acggtgcaac atacgtggga
    16561 atggaatagc ttcacggata tgttttgttc ctgctgcaaa ggttaccata cgttcgatac
    16621 cgataccaaa tcctccgtgt ggaactgtac cgtatttacg aaggtcaagg tagaattcat
    16681 attctgtacg atccatacca agttcatcca tcttagcgac aagggcatcg taatcttcct
    16741 cacgcataga cccaccgata atttctccat agccttctgg agcaagcaag tctgcacaaa
    16801 gcacgcgctc tggatttcca ggaactggtt tcatgtagaa ggccttgatg gctgctggat
    16861 agttcatgac aaatgttggc acaccaaagt ggtttgaaat ccaagtttcg tgtggtgacc
    16921 caaagtcatc accatgctca agatgctcgt agtcagcatc ttcatcattt tcatgctctt
    16981 gcaagaggtc aatggcttga tcgtaagtga tacgtttgaa tggctctgca atgtagcgtt
    17041 tcaagagttc tgtatcacgt tccaaggttt ccaaggcttg aggcgcgcgg tcaagaacac
    17101 cttgtagaag agctttcaca taagcttctt gcaagtcaag cgactcatca tgtgtcaagt
    17161 atgagtactc agcatccatc atccagaact cagtcaagtg acggcgtgtt tttgattttt
    17221 cagcacggaa aactggacca aagtcaaaga cacgaccaag agccatagcc cctgcttcta
    17281 ggtaaagttg acctgattgg ctcaagtagg ctggcgttcc gaagtagtca gtttcaaaga
    17341 gttctgtaga atcttctgcc gcatttcctg aaagaattgg gctgtcaaac ttcataaaac
    17401 cgttcttgtc aaagaactca taagttgcac agataatagc gttacggatt tgcaacacag
    17461 ctacttgctt acgagagcgt agccacaagt gacggttatc catcaaaaag tctgttccgt
    17521 gttcttttgg tgtgattggg tagtcttgag attcaccgat cacttcgatg tctgtgatgt
    17581 ccaactcata gccaaattta gaacgttcgt cctctttgac aatacctgtc acataaacag
    17641 acgtttcttg gctcaagcgt ttgataacat caaacttctc aagtcccact tcttcaccaa
    17701 atttttcgac aaagtttggt ttaaaagcca caccttgaaa gaaggctgtt ccatcacgca
    17761 attgtaagaa agcgattttc ccttttcctg atttattggc aacccaagcg ccaatcgtca
    17821 cttcctgacc aacatagtct tttacgtcaa taatcgttac acgttttgtc attatttttc
    17881 cttttctttt ttattcttta tggcaaacca cctctatatt gttcccatcc aggtcaatca
    17941 taaaagcagc atagtaaatc ggacgctcac ttcgataacc aggagcccca ttgtctcgcc
    18001 cacctgcctc taagccagcc tcataacaag cctaaacttc ttccttattt tctgctaaaa
    18061 aagcaaaatg aacaggatct tgtgttccct gagtcagcca aaaatcacca ccaggatgag
    18121 ggctgttcgg ggatagaaaa ctaattagag aactagtctt aaaagccaat ttatagtcca
    18181 aaggagcgag aaaactccta taaaatcctt ctgaaatttg taaatccttt accttaatct
    18241 caaaatgatc aatcattctc actacccata aatgctttca agcgttcgac tgcttcttta
    18301 agcgtgtcta ggtctgtcgc atagctgagg cggacatttt ctggtgctcc aaatccagct
    18361 cctgttacca aggccacttc ggcttcttct aagatagcag ttgtaaagtc tgtcacatcc
    18421 gtgtagcctt tcatctccat ggcctttttg acatttggga agagatagaa ggccccttgt
    18481 ggtttgacca cttcaaatcc tggcacctct gcaaggaggg gatagatggt attaagacgt
    18541 ttctcaaagg cctgacgcat gctttctaca gtatcttgct cacctgatag agcctcaact
    18601 gctgcatatt gggctactgc tgacggattc gaagttgttt gacctgcaat cttggacatg
    18661 gcagcgataa tgtctgcttc tccaacggca taaccaatcc gccaaccagt catggcatag
    18721 gttttagaca caccattgat gaccactgtt tgcttgcgaa tcgcttccga taggctagaa
    18781 atcggtgtga actcatgacc attataaacc aagcggccat agatatcatc tgctaggatg
    18841 agaatatcat tttctacagc ccagtttcca attgccaaga gttcctcacg ggtgtaaatc
    18901 atacctgtgg gattagatgg cgaattcagc accaaaacct tggtcttgtc agtgcgagct
    18961 gcttctaact gctctacggt caccttaaag tgattgtctt ccttagcaga aacaaagacg
    19021 ggaacgcctt ctgccatctt gacctgatct ccatagctaa cccagtatgg ggttgggatg
    19081 atgacttcat cacctggatt gaccacagcc ataaagaagg tatagagaga atatttggct
    19141 cccgcagcga ctgtcacttg atttgacgct acagaatagc cgtaaaagcg ctcaaagtag
    19201 ctattgacca ccgccttaag ctctggcaga cctgaggtta ctgtataaaa agaagcacgc
    19261 ccatctcgaa tcgatgcaat ggcggcatct tggatatttt tgggagtagt gaaatctggc
    19321 tcacccaagg ttagagacaa aatatctctg ccctcagcct tcagtgcttt ggcacgggct
    19381 ccagcagcca aagtcacact ttcttccatt tctaaaacac ggttggataa tttcataggc
    19441 cctccttgtt gaccaatgct cctgtttcaa aatctactag ataaaaatca gatcctgact
    19501 tgacttccca gattggctta tcttgataac gaccaaagat aatcttgtca atttcgccag
    19561 ctcccttttc cttagaaacc gtttctgctt tttcttgtga aacaccctga tttagctgat
    19621 aaacgtaaat cttatgatca tcttttccaa tcagaacagc aagtgcttct tgctgtttat
    19681 tacgaccaag aacgctgtaa taagattcca agccattgta taaatcaacc tgatcggcct
    19741 gctctaatcc tgcatactgc tgagctaatt tttctccttc acttttagct gtttgatagg
    19801 gtttcatgct aagagaaacc atatacagaa aggaagcact gataaccaca aacaaaatcg
    19861 tcatccctag accatactgc cacagtagat tattttttgc tttgttttgt ctttttttca
    19921 ctcgtctatt ttaccatcta ttaagcttta ttacaagtga atataagaat actcttcgaa
    19981 aatctcttca aaccacgtca gctttatctg caacctcaaa gctgtgcttt gagcaaccaa
    20041 ttctatttct cccttcaaac aaaaccgatt ttgaaagtga aacagttctt actttttcag
    20101 tcacaaatga ctagagtttc cgaaatttta caattttcaa ataaactctg agcaaatttc
    20161 ttgcaagttc ttttgttttg ttgtaatata ttttataaca acgagagagt tctcgaaatt
    20221 ttaagaaaaa ggagacacat catgtctaaa aaagtattat ttatcgtcgg atcactacgt
    20281 caaggttctt tcaaccacca aatggcgctc gaagctgaga aagcacttgc tggtaaagcg
    20341 gaagttagct accttgatta ttcagccctt cctctcttca gccaagattt ggaagttcca
    20401 acacatccag ctgtagctgc tgctcgtgaa gcagttctcg ttgcggatgc tatctggatt
    20461 ttctctccag tctacaactt ctctatccct ggtacagtga aaaacttgct tgactggcta
    20521 tctcgtgccc ttgacttgtc tgatacacgt ggcgtttctg cccttcaaga caagtttgtc
    20581 acagtatcat ctgtagccaa tgcagggcac gatcaacttt tcgctatcta caaagacctc
    20641 ttgccattta tccgtacaca aggcgttggt gatttcactg ctgcacgtgt taatgactct
    20701 gcctgggcag acggaaaatt ggttcttgaa gaaacagtcc taaactcact tgaaaaacaa
    20761 gctcaagact tggtcgaagc gattcagtaa aaaatagaaa attttagaaa gtctaaatca
    20821 attatagcca cctaataggg tggcttttta tttctcaatc aagattttca gacaaacatc
    20881 agccatccaa aaaaaccttg agcgttacca ctcaaggttt ttagcagtct tttccatcat
    20941 aggaaaatca ttctaagaat attctttcat tcgagatcta tcacttatca tcttctttcg
    21001 agaaattagt gactgctttt ggctgattaa tcttcttttc ttcgtcctac atataggctc
    21061 aatagaatac cgctacctaa aagaacagag atataatcag attggcttcc agtttcaggt
    21121 aatttgtccc cacggttttc tttacctgta gttggtgcta ctgggttagc atttactgga
    21181 gttgctggtt gagccggtgt tggtactact ggttgttctg gaaccgctgg tactggttta
    21241 accggtactt ctggtgttgg aacagctgga gttggttgta ctggcacttc tggtgtcggt
    21301 acatttggtg ttggttgcgc tggcacaggt ttaaccggta cttctggtgt cggcacattt
    21361 ggtgttggtt gcgctggcac aggtttaacc ggtacttctg gtgtcggcac atttggtgtt
    21421 ggaggaactg gtttgtcatt tgatggtgtt actggtttgt cttggcatcc acattttcca
    21481 tctttaccgt ctttgccgtc tcgaccatca cgtccatctc taccatcttt gccatcttta
    21541 ataactgttt ttgtcacagt tccatcagaa ttgatgattg tgattgtatg actaccatca
    21601 ccattatctt caacagaaac ttttggtgat ttaccatctt taccgtcttt aatcaccatt
    21661 tctgtcttac ttccatctgg attagtgatt gtaacaacgt gagttccatc gttattattt
    21721 ttaacagtta cagttggtga aacgctatct ttgccgtctt taccatcttt gataatagat
    21781 ttgtattcac gaccatcaga atctacgatt gttaatgtat gagttccatc tccgttatca
    21841 acgatgttcg cttttggtga tttaccatca aagattgtag ttgtcgttcc tttaccatca
    21901 gcacctgtca ctttaatagt gtgtgaacca tcgttgttat caataacttc aagttttggt
    21961 tctctaccat cacgaactgt agttgttgta gttgttccgt ctgagttcac aactgtgata
    22021 gtgtgagttc catctccatt atccacaacc ttagcagttg gtgatttacc gtcacgaact
    22081 gtggtttcag aaacagtacc attaccgttt tccacacgaa tagtgtaagt accatcttgg
    22141 ttatctctaa ctgttgctac tggtgattta ccatctgtaa tgattgtttc agtagttgtt
    22201 ccgtcaccat ttagaacaga gatcttatga gttccatttt gttcatcagt tatagtcact
    22261 tttggtgatt taccatcacg aactgtggtt tcagttgtca caccttctgg atttgtaata
    22321 acgattgtat gacttccgtc tccattatca cgaacagatg cggttggagt acgtccgtca
    22381 acaccgtcac gtccattctt aacaacaaac tcattcttag ttccgtctgg gttagtgatt
    22441 gttactgtgt ggcttccatc tggattttca gtagttgttg ctgttgcagc tttaccgtct
    22501 ttaccatctt tgatgatagc gttggtaaca ttgccgtctc catctgtaac tttaacagta
    22561 tgagttccat cgttgttatc cgttacttca actttaggag tcttaccgtc tttaccgttt
    22621 ttaacaacag tttctttagt tgaaccatct ggatttgtca ccgtaattgt gtggcttcca
    22681 tctgggtttt ctgttgtagt gatattcgca gttttaccgt ctttaccatc tttaacaact
    22741 gttgttgatt cagaaccatc tgggttttga actgtgatag tgtgagttcc atctccatta
    22801 tcttttgtag taatagttgg agctgaacca tcacgtccat ctataccgtt ataaatatct
    22861 ttactattta atactttatc gacaccttcg tcgtataccc cattgtcatt aacatcatca
    22921 taaactgtaa cacggatacc gttacgcgtt ggagttgcag cagcatctgt agcgcgtcta
    22981 attcttgaag gtgaagtaat atcttctact ttgattttcg gtgcacggcc atctttacca
    23041 ttcttaccat cttttacagt gaaggttact ggatctttac ctggtgttgt gatagttaca
    23101 acagtgcttt ggccatcttg tccacgttga gtagtgattg taggagtttg tccatcctga
    23161 ccggttgcac cagtttctcc cttagcacca tcttgaacaa agactgtagt tggttgtgaa
    23221 ccatcatggt tatcaacagt gatttctaca cctttatgcc ctgcttcatc tttacgaaca
    23281 gctgtaactg taggtgattt tccatctact ccatctctaa ttaccgcaag tggtttttct
    23341 ggatttaatg gttgtcctgg gttagctgga tcttcttggt aaactttagt ttctttacca
    23401 tccttgacag taagcaatga tttaccatct cgtccgtccg cgcctttagc accatcttta
    23461 atcatttctg aacctagaag ttcatcagtt cctggtgtat atttaccgtc attgttttca
    23521 tctgtataga atgtcacaat tgtatgagat ggatttccgt tttttccttg gacacgaagt
    23581 aaatcaactt ttggagtttt accgttcaga ccattttctc cgtccttaac atttactgta
    23641 actggatctt tacctggaac agtgaatgta atgtcagtac tatggtcatc tttacctgga
    23701 gttacagtta cttctggagt cttaccatct tctccgcgtt cacctttgtc acccttaggg
    23761 cctttgatgt tgccctcttt atcccagttg ccgttattct taacgaagac gtcgcctgtt
    23821 tctgtattaa cgtatttatc gccgtcttta ccttgatgtg cttctgggtt agctttgccg
    23881 ttcaacacgt ctttaccgtc acgtccatca cgacctactg cgccatccgc acctttagct
    23941 ccttgcgctc cagttaggcc gcgttcgcct tggtctcctt tttcgccttt agcaccatct
    24001 gcacctttgt cccctttagg gcctttgatg ttgccttctt tatcccagtt tccattgttt
    24061 ttaacataga catcaccggt ttcggtatta atatatttat ctccattttt accttggttt
    24121 ggttgtggat ttacttttcc gtttaataca tctttaccat cacgacctgc ttgtcctgta
    24181 gctccatcac ggatcgtagt tgtcacatct ggacttcctg gattatgaac cgttaatgta
    24241 tgtgtgccgt tttgcccctc agttattgtt actgttgggg ttttcccatc agcacccttt
    24301 tgtccatcct ctacaaatgt tgtttgtgga cgacctccta ctggtgtaat tgttactaat
    24361 acaccatttt tgccattttg cacacttcgt gtcgctgtaa ttgttggtga ttgtccatta
    24421 gtaccgtttc ttccatcagt gatagttgct aatggttggt ttggattaag tggttgtcct
    24481 ggtctagccg gatcctctac atagactttt gtttcagttc catttttaac agcaattaga
    24541 gattttccat ctttacctgg agttcctgga ttaccttgtt ctccttttgg tccttgtggt
    24601 cccgctggtc ctctttgtcc atctgcgcct tttggtcctt gagctccatc acgaccttga
    24661 agaccttgtt cacctttggc acctttggca ccttgcgctc cagttaaacc gcgttcacct
    24721 tggtctcctt tttcaccttt agatccagtt agaccgcgtt caccctgttc tcccttttca
    24781 cccttgacac cttgcgctcc agtcaggccg cgttctcctt gggctccttt ttcacccttg
    24841 gcaccatctg cacctttgtc acctttcggt cctttgatgt ttcctgctgg ttcccaagtg
    24901 ttacctttct taacgaatac atctcctgtt tgtgtattta cgaatgtgtc tccatcttta
    24961 ccttctgttg ttgggtctac ttttccgttt aatacttctt ttccatcacg tccagatgct
    25021 cctgcagctc cgtcttgtcc gtctttaact actgttgttt gaactaactc gtcttttcct
    25081 gctgtgtaac ttccatctcc atctttgtca atgtagaatg ttaatgttgt ttgtttcttc
    25141 gcatcatctc gttctgcttt gacttttggt gtttttccat cttcaccgtt tttaacgatt
    25201 gttgttaatg atggtctgtt gtctggttgt gtgattgtga tggtgtgtgt tccgttattg
    25261 ttatctgtaa ctgttacttc tggtgtgaat ccatcttttc cgttatcacc tttgtcacct
    25321 tttggtcctt gttttccatc tgcaattaca acttctttaa gttttgtatc tccttcatca
    25381 aattgattat tatcatttag atcataatag aaaataacag ttgttgtttt atctgcttca
    25441 tttctatgag tagaaacaag agggcttgca ccatcaaatc catctcttac tactgtagta
    25501 gttataccac ctttaccatc gttaattgta attgtatgcg ttccatcttg accatcagtt
    25561 actttaactg ttggggtttt cccatcttct ccttttggtc cttgttcacc atcacgccct
    25621 tgaagacctt gttcaccttt gtcccctttt tcacctttag caccatctgc aattacaact
    25681 tcttttaatt tcttatcaga agcatctaat tcattgtttc catttttatc gtaatagaag
    25741 ataacagttg ttgtcttatc tgcgtcattt cgttgagtcg caactaatgg acttgcgcca
    25801 tcgaaaccat ctcttacaac agtacttgta acattacctc taccgtcgtt aatagtgata
    25861 gtatgagtgc cgtcattttt attatcttta acggttacgg ttggagttac accgtcacga
    25921 cctgcctgac cttgggctcc agtgagaccg cgttcacctt ggtccccttt ttcaccttta
    25981 gcaccttgtg ctccggttag accgcgttca ccttgggctc ctttttcacc tttagctcct
    26041 tgagctccag ttagaccgcg ttcaccttgg gctccttttt cacctttagc tccttgagct
    26101 ccggttagac cgcgttcacc tcggtctcct ttttcacctt tagctccttg agctccagtt
    26161 agaccgcgtt cacctcggtc tcctttttca cctttagctc cttgagctcc agttagaccg
    26221 cgttcgcctc ggtctccttt ttcaccttta gctccagtta gaccgcgttc accttggtct
    26281 cctttttcac ctttagctcc atctttaata gcaatttttt gaacaagttc gtctacacct
    26341 tcagtataaa caccgtttcc atcgttatca agatagaaag tgaggttatt tgtatcaccg
    26401 actttatttt gatcaacacg tggttttact gtatcgatta gatctttagc cacaccaatt
    26461 tgcataatac gtggcttagc ttctttagta acactattac taatcggcaa tcctaaaagt
    26521 gtttcgttac caaatcgatg aactttatag gtaatttgac gttgtccttt ttcaccttct
    26581 cgaactaatc tagtttgacc ttctggtaac ttactagttg gaagatagac agtttggaag
    26641 tcaatgtctt ctgaaacagt cttattatta gtaccaccat aagggtttgc atccaagtat
    26701 agtgggtttg ctctataata atagttagag ttactgtatg ggtcattgct agtagcggca
    26761 ccaccaccac cttggtccac gttaaaagta acaggtttca aacgaacaga caaatcacca
    26821 tttagattaa tgataggcaa actaaatctg atagtttgtt ccgtatttgt tgaaatagca
    26881 gaggtcatac tgtatcctga gtgagatacg tagttggcac cctgactaat agattttgat
    26941 tgctccctta ctcttggatt tgaacttgtg atcgttgcat ttgaaggatt tccaaatcca
    27001 tcccctttat ccaagataaa attattatta acaaactctc tagaatctcc tggcgcagaa
    27061 taactaattg taaagttaac actattacca ctacgtactg ttgttacatc gtaatgaata
    27121 gaatttccac cacgtgagtt cccgtagcca cggaaactat agctacgacc accttggcta
    27181 atatctgcaa atgcaactgt atttccagaa cctgagacaa ttgggttggc tggattgcta
    27241 gccgctctaa aaccactata ccctctatta acatcttcct tacggatagc tggattttgg
    27301 cgagcatcag aaaggctcaa acctagtttc aagatttcat taatagatgc tggagctgaa
    27361 gttgtttcta ctttgtcagc tgtgctagtt ggcaaaatag cgctatcaac agctgaacgt
    27421 tcagttgttg cagctggttt agccccttct tttgattcaa ctgcatcagc tttcttcgct
    27481 acaggcgttt ctgatacagt ttctttatta gagttagaac gaagttctag accaataata
    27541 aatgattgaa tagatgactc tgctgctgat aattcagctt cagttgcatc tgcttttcca
    27601 agcaagcttt gaccagcttg gatacttgtt tgcaagttag cagcacttgc ttctgtatat
    27661 aacttgcttt ctaatttttt agcacgcgaa agagccgtta ataattttga cttgtcaacg
    27721 gcatcttgat gcgttacttc ctcttttttg tcttttgctt cttcaacttt ttctgctggt
    27781 ttagtaactt cttcagtttt aactggagtc gtttctactg gattagctac agttggagct
    27841 gcataggttt tctctttatt agacgcagaa acctctgctg gtttagtagc tgcttctccc
    27901 ctaccaacag aaatactatt ggtagtttct tgtttgtttt cttccgcttg tactgtttgg
    27961 acactagctg ctgcacctaa taccaaagcg gtaccgagca agacactagc tgcaccaaag
    28021 taatacttac gaatagaata acgttgttgc atgctatacc agtcaaatga ttttttatgt
    28081 gaatgtttca ttttaaactc ctagatagta ttttatagtt tacaatgtac aactatttga
    28141 ggcattaatc aatattttct gaacaattaa tatattctgt ttttgcactt aaaagccact
    28201 tatattattc taatttttcc gattactaac gacaattttc ttgctctaat ttttttatac
    28261 tacttagaca aaaaaagata taatgaatta tggaggaaat acccgtatga gaaacctttt
    28321 atccacaaaa gttcaaagac aattacgctt aatggaaacc ctaattcaga atcgtaattg
    28381 gatgaaatta catgaactag ccgaaaaatt aggatgtaca gaacgaatct taaaaagtga
    28441 tttaaatgaa ttacgtattg cctttccatc tattaacatc caatcttctg ttaacggaat
    28501 catgatagat ttagaagtta acactagtgt agaagatatt tatcaatact ttcttgctaa
    28561 ttctcaatct tttcaattac tagagtatat gttcttcaat gaggggctac ctatttatcg
    28621 aacaatagaa aatctttact ttagtagtgc caacctctat cgactgggca gaaatattac
    28681 aaaggttctt tcatctcagt ttcaaattga attatctttt actccatccg agatacgtgg
    28741 aaatgagatc gatattcgtt acttttttgc ccaatacttt tctgagcgct attatttcct
    28801 agattggcct tttcctgacc ttcctgagga agatttaaca gagtttgctg acttcttcta
    28861 taaaatcaca aattatccaa tgcgattttc aatttataga atgtacaaac tgatgatagc
    28921 tatcagtatc cacagggtta aaaatggtca cttcattgac ctccccaacc acttttacaa
    28981 agaatattat cctcttttaa agagcattcc gaatttccag gagacacttg cttatttctc
    29041 taaacatttt gggcttgaaa tgactccaga tacaatcgct caaattttta tttcttttct
    29101 tcagaatgat attttcctag atcctcaaga attcttcaac tctttagaag ataacagtca
    29161 agcaagatac tcttaccaat tacttagtca aatattagaa ggcctatcaa aacaatataa
    29221 gattactttt actaaccacg atgagctgat ttggcattta cacaacactg ctttctttga
    29281 aagacaggaa atcttttcta ccccaatctt atttgaacaa aaagcattga cgattaaaaa
    29341 atttgaagtt tacttcccag actttatggg aagtgcgcgt caagaattgg ctcaataccg
    29401 tcaggcaatt ggacagcatg accatcctga acagttggaa cacttgatgt acaccatctt
    29461 aacccatgct gaaaacctct ctactcagtt gttagaaaat cgaccaccta tcaaggtttt
    29521 gattatcagt aactttgacc atgctatatc ccttaccttt gttgatatgc tttcctatta
    29581 ctgtaataac cgctttacct tcgatatttg ggatgaatta aaaacaagtc ctgagatttt
    29641 aaatcagaca gattacgata tcatcgtgtc taatttctat attccaggga ttaccaagaa
    29701 gtttatttgc cgaaatcatc tgtcaatcat gaatttggtt aatcatctta acaccttatc
    29761 aaatgagatt catttgtcca atactttata agttatcaaa aaagtcagca taatcgtgct
    29821 gacttttctc ttatctgatt tctatacttc ctttacaaaa accaatccct gtggttgtga
    29881 caaatcttct cggtaaacaa atccagcaaa gttcaagcga cgtgcttccc ccacagtttg
    29941 tacttgattt tctattaaag ctgttagaaa ggccccgcgc gctttcttgg agatagttga
    30001 gtgaatcttc agctgaccgc ctctatcctc catgaatttg aaggtcacca tctttgctct
    30061 gatttcctta gaaaatacag tctcaaactc tgatgacaag agagagaaaa tcacttcttc
    30121 cttcttcaga gcttcatcat agactgcctt ccaatggctc ttcaaagtct taccagcgac
    30181 ttttaatttc atcaaaaaat ccaaacggtg aggagccatg ggtgacaagg ctggaacaac
    30241 accgtacaaa gccgaggtaa tgaagacatg attttcaaga taatcttgtt ccgcctcggt
    30301 cagcttatct ctcttaatgt tgcggtacat aagcccatca aaaagtttca aggctggata
    30361 gtgttgagca gtttgccttt tcaaagcttg gatattttga aattcttccg ccgctttctc
    30421 agctgatacc ttgtagaaac tctccaattg actggcagaa tagagagcca aggcatcaag
    30481 cacggtctga ctttctggtt ttaaaggaat tgcctcgata cttggcaagt ctgtgttcat
    30541 ttcttttgct gttgggatta aaattttcat attgatagtg tagcatattt tttagccaca
    30601 accaagaaat tcatttgaaa aacctcggtt tgaccgaggt ttttctattt atttgggcca
    30661 tcctaaccag acagccgcga gaacaagggc tatgccagct aaacttgtta agatagataa
    30721 gaatttatct tttttctcct tgaactgaga aaaacctatc ttcaaagcga gcagtccgag
    30781 tagcattgaa gcaaccatca aataaaaacc catttctttg tcctccatta ggcttaattt
    30841 accttattat aacatatatt tcttaaataa acctttttta tactcaatga aaatcaaaga
    30901 gcaaactagg aaactagccg caggctgctc aaaacactgt tttgaggttg cagatagagc
    30961 tgacgtagtt tgaagagatt ttcgaagagt attattgtac tttaaaggtc ttgagataat
    31021 tgtcttttcc tacttgacct tcgaaggttt taccattttc aaggtaagga aggtcatcgg
    31081 atactgaagc cttgaccttg tatatcttgc catcaacttt aaagaagtag acagtgtctc
    31141 ccttgataac agctgatttg aggtctgcta ctactccctt gatgctttct gtcgttgcat
    31201 tgtcaatttc aaggtcgttt ttattggcat acttgctgag catctcttcc actgtagtag
    31261 caacgataac attttggtac tcgactgcgt ctaccagggc gtactctttg accaagccag
    31321 cattgtcctt taagcccatg atgtagagag gcttgtcatt gaggttgatg aggattggga
    31381 aggttgcttt gtaggatttc tcctgaacag caccttctgc tgattcacgg gctgattctt
    31441 ctgtcgcaga agccaagcta tacttagtaa tttctcctgt tcgcatattt tcaaggatga
    31501 aaccaagatt actctcatcc gcattagccg acgtcacacc tgtgtagaga tagatgtcat
    31561 taccgataga caagtaatta tagccattgg tagtctgggt cacgtttttc ttggaaatca
    31621 tggcattcaa gaaaccgtcc ttgtacttgc cgttgtagtt gatttgctca atggtttcct
    31681 ctgctggata gatcctgtcc acccattctg gaacatctga taagctgtat tccttggttt
    31741 ctccatttgt agcatccaag ataatgactg aagcaggacg aggaaccgca agtccaaatt
    31801 gcttttggta aaccgttgct acatagaaag gattgccctc atcgtccacc tcaaaagatg
    31861 gagttttaaa gattttagtc gggtacttca agcgcaggtg acgtttgaca tcacggttaa
    31921 aatactccga gtctgaatac ttgattggtg tcttcaagtc caccaaatcc gcatttccag
    31981 ttaccatgtc caccttgata tactcaccga ttcccttggc ttgattgtta aaccatttga
    32041 tagggtctgc atattctagt ggtgtgaccc gataaggttt cccatcaatt gtcaattggg
    32101 tataggtatc tgccgctacg tattgcgaca ccttatcggt tagggaaccc aagtagcggt
    32161 ctccaatttt ttcagcagta cttctatcta ggataggaac cttactggtg tcactcctag
    32221 gaaattcagt aaagtctttt tccgtaaccg tgactacatt ggcataattt ttagcctgaa
    32281 acatgctgga agttaccaag gaaaccaaag ctgccaagag aagaattcct ccaatcgaag
    32341 ctaacagaat tttccctaac cgattgattt tgaaaccctc aagatttaag gcagcttccg
    32401 ccttaccgtg gcgcacatga accgttttga caaggtttat ccccttgcca aagccaaata
    32461 agattgccac aactaacaaa tgcccacaga ggaagaagag aaattcccag ctggtcaggt
    32521 taaggggcgg taaaaagata taccaggtcg ttgcgataaa aataagttca cagactattc
    32581 gtttcatttg ctttcctcct aaatgattcg tccttccaag tgatccagct catgctggca
    32641 aatctgagct gggaagcctg tcaaggtaat ggtctgttcc tgccacttgc tgtcacgata
    32701 ggcaagcctt gtggtttcat aacgcttagt tgatctcaca cctaccaagg acaaacagcc
    32761 ttcttctgcc tcataggatc cttcaaagga cagaagcact gggttaaaca tgaccacggg
    32821 aaccaagcca agattaaaga taatcacgcg cttctgcacc ccaatcatat tggcagctag
    32881 accaacacag gtatcacgat ttgctaagag tgtatcctgc aaatctctgg caagataaag
    32941 gtcctcctga cttgccggct gagacacttg agataaaaat aagatatcct tcacaatttt
    33001 cttttccact tcctcacact cctcttgctt tttactatat tatagcaatt atagcacaaa
    33061 agccgataac tgcaaaccct ttccctcaac tgtagcaaaa agccatccga agatgacttt
    33121 tttgctattt aatttctgta taagttactt ccaagccacg cttaacagct ggacgattgg
    33181 caattttttc tgcccatttt actagatttt gataacttga ggcatccaag aattttgcag
    33241 aaccttggta aagatttcct tgaactaact gtccatacca agaccagata gcaatatctg
    33301 caatcgtata gtcattgcct gcaatataag gtttctgagc caattcctta tccaataaat
    33361 ccaactggcg tttcacttcc atcgtaaaac ggttaatagg atattccaat ttttcaggag
    33421 cataattgaa gaaatgtcca aatcccccac ctagaaaagg tgctgcacct gcttgccaga
    33481 atagccaatt caaaacttct accttttcca caggattact tggtaaaaag gctccaaatt
    33541 tctcagcaag gtaaagaaga atatgagcag actcaaagac tcttacatct tcagtacctg
    33601 actggtccaa taaggctgga atcttggaat ttggattgag cttcacaaag tctgatccga
    33661 attgatcccc atccatgata gcaatcttat acaagtcgta agccgcttcc ttaaaaccag
    33721 cttctagtaa ttcttccaat aagatagtaa ccttcacacc atttggtgtt cccagtgaat
    33781 aaagctgaaa agcttgttct ccttttggca agttttgttc gaaacgggca cctgctgttg
    33841 gtctgtttag ccccgtaaaa gctccttgat tactagcttc atcctgccat acggtcggta
    33901 attgatatgc tgacatccga gacctccctt aaatcgcatt cttgtcaaaa ccgagtttgc
    33961 gttgaataaa cttaacgatt tcgacgatga taatcattga gaagcttcca gccataacaa
    34021 ttccccattg tgacaagtct agtttggtta cgtggaagat tccttcaagc ggttctacaa
    34081 cgattgttgc catgagaagg ataaaggata ccaagatgga ccagttaaag gtcttagact
    34141 tgaatgggcc aactgtcaag atggattggt agacagactt gacattgtag gcatggaaga
    34201 gctgaatcaa accaagggtt gcaaaggcca tcgttagggc atctgcatga atagcatgat
    34261 tgtcacccac atgaactggg taagcaatcg caaggccata aacactcata acaagagctg
    34321 cttggagtac accttgataa atgatagaac tcaaaacacc acctgagaag aagcttgcct
    34381 tgcgtccacg tggtttatga ttcatgacac caggttccgc aggttcaaca ccaagagcga
    34441 tagctgggaa ggtatccgtt accaagttga tccacaaaag atgaaccggc tgtaagacat
    34501 cccaaccaaa caaggttgat aggaagatgg ttaatacttc agcagtatta gcagaaagta
    34561 ggtactgaat agtcttttga atgtttgaga agaccttacg tccttcttcc actgcgacga
    34621 taatagtcgc aaagttatca tctgcaagaa tcatatcaga agccccctta gaaacctctg
    34681 taccagtgat tcccataccg ataccgatat cggctgtttt cagagctggc gcgtcattga
    34741 caccgtcacc tgtcatggca acgactttac cttgtttttg ccaagccttg acgatacgaa
    34801 ccttgtgttc tggagacaca cgggcataaa cagagtattg accaacaact ttttcaaatt
    34861 cttcatctga cagttcattg agttcagcac cagttaaaac gtgaccttct gtatcgtttg
    34921 cgtcaatgat tcccaaacgt ttggcaatgg cttccgctgt gtcttggtgg tcacctgtaa
    34981 tcataattgg acggattccc gcttccttag ccacacgaac agcctcagcg gcttcaggac
    35041 gttcagggtc aatcatccca atcaaaccag taaaaattaa atcattttca agctcttcag
    35101 aagtgagatt ttctggaatg ctgtcaataa tcttataagc acctgcaagg acacgcaagg
    35161 cttgatgagc catttcagag ttgtttgtat gaatgagatt tgtaaccttc tcatcaatcg
    35221 gagcaatatc cccagcctta tcacgaagaa gacaacgttt taagagttgg tctggcgcac
    35281 ccttgactgc tacaaggaaa cgaccatctg gcaatgggtg aactgttgac atgagcttac
    35341 ggtcagagtc aaatggcaat tcagctacac gaggatattt ctctaagaaa cctttgacat
    35401 catagccctt gtccaaggca tattggataa aggctgtttc ggttgggtca ccaatcaagt
    35461 taccttccac atcgattttc gtatcattgg ccaagacaac tgaacgaagt agtggcattt
    35521 caagacctag ttcaatatca tcagctgagt catgtagaac cgcatcgtag aagacttttt
    35581 cgactgtcat cttgttcata gtcagcgtac cagtcttatc agaagcgatg atttcagttg
    35641 aaccaagtgt ttcaactgct ggcaacttac gaacgataga atgtcgtttg gccaaaactt
    35701 gagtaccaag agaaagaacg atggtaacga tagcaggaag tccttctgga atggctgcaa
    35761 cggcaagggc aacagaagtc aacaactcac caagtggatt tttcccttga atgaagacac
    35821 ccactacaaa agtaacaagg gcaatgacca agatagcata ggtcaagacc ttagaaaggt
    35881 tgttcaaatt ttgtttgagt ggtgtatcag tctcatccgc atcttgaagc ataccagcaa
    35941 tatgaccaac ttcagtgtac atacctgtat tgacaacaac acccatccca cgaccatagg
    36001 ttacgtttga gttttggaag gccatgttga cacggtcacc aataccagca tctgtcgcaa
    36061 gctcgactga caagtctttt tcgactggta cagattcacc tgtcaaggct gcttcttcaa
    36121 ttttaagaga gttggcttct atcaaacgta ggtccgctgg taccacgtca cctgcttcaa
    36181 gggcaacgat atcgcctggt accaattctt tagagtcaat ctctgccatg tgtccatcac
    36241 gaagaacgcg ggcaactgga ctagacatgg atttgagggc ttcaatagct tcttcagctt
    36301 ttccttcttg gtaaacacca aaggcagcgt tgatgataac cacagctagg atgataatgg
    36361 catctgcgat atcttcccca ccagaagtca cgactgacaa gattgctgcc gcaactagga
    36421 tgataatcat caaatcctta aattgctcga tgaatttgac caagattgat cgtttctcgc
    36481 cttcttcgag ttcattgtgc ccaaattcgg caaggcgctt ttccgcctca cttgatgaca
    36541 aaccttgctc ggtcgcatcc acagcctgca agacctcttc agggctctga gtataaaacg
    36601 cttggcgttt ttgttctttt gacatgtgtc tcctccttga cattgtgtgc aaaacagact
    36661 ctctttctgt catatctttt cacgacaaac aaaaagagac ctgttaatca taacaagtct
    36721 cgctgtttaa gatagggccg gaaagcatac ttttcagcat aaaattcgga atgacgacac
    36781 tatcacaggt ttctgccagc tactcccttg agtagtacca ttataccaaa ttttggggag
    36841 ttttcaaaga gtaaaaactg ccttatttga atttttcctt gaaaaccagt ataatggtag
    36901 aatgctatgt gactagaaag gaagttgaat gaagcaatct atctcaaatc tcaagttagc
    36961 tgagcgtgga gccattatca gtatttcgac ctatttgatc ttgtctgcag ccaaattagc
    37021 agctggtcat ctccttcatt catccagttt ggtggccgat ggttttaata acgtatcgga
    37081 catcattgga aatgtggccc tcttaatcgg gattcggatg gcgcgccagc ctgcagaccg
    37141 tgaccaccgt tttggtcatt ggaagattga agatttggca agcttgatca cttctatcat
    37201 catgttctat gtcggtttcg atgttctaag agataccatt caaaagattc tcagtcggga
    37261 agaaacggtc attgatcctc ttggtgcaac tctaggaatc atttctgcag cgattatgtt
    37321 tgtggtctat ctctacaata ctcgcctcag taagaaatcc aactccaagg cgctgaaggc
    37381 agctgctaag gacaatcttt ctgacgctgt tacctcactt ggaaccgcca ttgccatcct
    37441 agctagtagt ttcaattatc cgattgtgga taaactggtt gctatcatca tcactttctt
    37501 tatcttgaag actgcctatg atatcttcat cgagtcttcc tttagtcttt cagatggctt
    37561 tgacgaccgc ctgctcgagg actaccaaaa ggctatcatg gaaattccca aaatcagcaa
    37621 ggtcaaatcg caaagaggtc gcacctacgg tagcaacatc tacctggata ttacactaga
    37681 gatgaatcct gacttgtctg tttttgaaag ccatgaaatc gcggatcagg tcgagtctat
    37741 gctggagaat cgttttggcg tctttgatac cgatgtccat atcgaaccag cacctatccc
    37801 tgaggatgaa attttagaca atgtctataa aaaattgctt atgcgtgaac aattgatcga
    37861 ccaaggaaac caactagaag aactcttgac tgatgatttt gtctatattc gccaagatgg
    37921 agagcagatg gataaagagg cttataagac caaaaaagag ttaaattctg ctatcaagga
    37981 cattcaaatt acttccatca gtcaaaaaac caaacttatc tgctatgagt tagatggtat
    38041 catccatacc agtatctggc gtcgccacga aacctggcaa aatatctttc atcaagaaac
    38101 caaaaaagaa tagagaaatc ctttcatgag acgggatttt tctattcgtt tatactcaat
    38161 aaaaatcaaa gtgcaaatta ggaagccggt cacaggctgt acttgagtcg gcaatgtgaa
    38221 gccgacatag tttgcacttt gattttcgaa tagtcttaac tatcaaattc actgagatac
    38281 tcatagcgtt cgtatttttc aaggagtgct tcatttttct catccaattc tttttggaga
    38341 gtagccagct taccaaagtc agagccgtta gcctgcattt cctcttcaat agcagcgata
    38401 cgtttttcca aggtttcaat atcaccttca atacttgccc actcctgctt ttcttggtag
    38461 gtcatgcgtt tcttgtcttc tcgaaccttg accacttttt ccttttcgac cttttgcact
    38521 tgattgacca tatctgtttc aaaagctttt tcatcaagat agtcggtgta atgaccaaag
    38581 aaaggacgaa tcttgccatc ctcaaaagcg agaatcttgg tcgctacctt atccaagaaa
    38641 tagcggtcgt gactgactgt taaaacggga cctgcaaaac cttgcaagaa attctctaag
    38701 actgtcaaag ttgcaatatc taggtcattg gttggctcgt ctaaaagaag aacatttggt
    38761 ttttccaaaa gcagtttgag gagataaaga cgttttttct caccccctga caatttctca
    38821 atcaaggttc catgcgtcga acgtgggaaa aggaactgct ccagcaactc tgcaatcgaa
    38881 gtcgtagaac cgccactggt cttgacctcc tctgccactt cctgcaggta attgataact
    38941 ctcttgcttt catccaaacc ctcaatttgc tgagagaaat aggcgatgcg aacagtttcc
    39001 ccaatcacaa cttgtccttt agttggctca agacttcctg caatcaagtt gagcagggtt
    39061 gattttccaa caccattgtc cccaacgatt ccgatacggt ctttggcctg caccaagaga
    39121 ttaaaatctt gcaaaatagg cttgttttca taggcaaagg aaacagcctg aaactcgatg
    39181 actttcttcc caatccgact ggtttcaaag ttcatggtca agtctgtctc agcactactg
    39241 cctgaaactt cctttttcag atcatggaat cgattgatac gggcctgctg cttggtcgca
    39301 cgcgcctgcg gttgtctgcg catccaggcc aattcttgtt tgtagagttg ttcttttttg
    39361 tgaagaagag ccgcgtcgcg ctcatcctgt tccgccttta ggcgaacata gtcctggtaa
    39421 tttccctggt actcggtcaa gcctgcacga tccaactcga aaatccgtgt tgacaaagcg
    39481 tctaagaaat aacgatcgtg agtgataaaa aggacggtct tcttagaatt tttcaaaaag
    39541 agggtcagcc actcaataat cgcaatatcc agatggttgg tcggctcatc caaaagcaag
    39601 aggtcgtggt tgccaagtaa gacttgtgcc aactgtaccc gtcttctcag accacctgac
    39661 aattccccaa caggagtaga taagtcttga atgcccaatt tgctaagaac ggtcttgacc
    39721 tgactttcga tttcccaagc ttggagagag tccatctctg ccatgacacg ttccaaacgc
    39781 gcctgcttgt cctcactata gtcgagcata atcaattcat actcacgaat gagctggatt
    39841 tccttgagtt cactagatag aaccgtatcc aaaactgtct ttctatcatc aaaatcagga
    39901 tcctgagtca agtaaccaat ctggtaatca tttttagctg aaaaaggact gacatcccca
    39961 tcaaatccag aaacaccaga aaggacgtcc aaaagggtgg tcttgccagt cccattgaca
    40021 ccgattaaac caattctgtc taagtcatgg ataataaagg aaatatccct aaaaacggtc
    40081 ttgtcaccaa cggatttact tagtttttca acgataaaat cactcatttt ttctccctca
    40141 ggtaagcatg gatggcttca cgattattct ccaattctcc atcgacaatg gcaaactcaa
    40201 tctctgttaa aatctctccc aagtctgggc ctggctgata gccatattcc ttgatcaaaa
    40261 taccgccatt aatctgaatc tctttcttgt catggatagt caagctttgg tatttttctg
    40321 tgatggcttg tgggttgact tcttttcctt gagcttgacg aagattttca gcctgtaaaa
    40381 gcaaatctat gtcaaagcga taacaatctc gcttgctcaa ttctccattt tcacgcagag
    40441 ccaaaataat cagcaaatcc tgaacttgct tggcaaactg gcgtgaggtc ttccaagatt
    40501 tcaaaaatga ctgcgcattt tcaatctcca aagcccatag taaagccgcc caggcttgtt
    40561 cagaggattc aaaagtaaaa tcagtctcca aatcaaacag tctgttgagc ttgtcctggc
    40621 tagatgccat atcagggaga tagtcataag cttgactctc aatcatggaa gccaagcccc
    40681 ttctccaaaa tggagccagc aagagtttat caaactcgac gaaggtacgc tctacagaaa
    40741 ttttctccaa aagcggcgtc aaggtcttca tagctttaaa tgtttctggt tcaagtgcaa
    40801 aaccaagact agcctgaaaa cggaaaccac gcataatccg taaagcatct tcgttgaaac
    40861 gctcactagc cactccaact gctcgcaaga cttgcttttc caaatcttct aaaccatgga
    40921 acaagtcaac gatttctcct gtctcatcca aggcaaaggc gttgactgtg aaatcacggc
    40981 gtttgaggtc ttcttctagc gagcgcacaa aggaaaccgc actgggtctg cgatagtcca
    41041 catagacatc ctctgtccga aaggttgtta cctcatactc ctcatcccca tctaagacca
    41101 agacggttcc atgctcgatt ccgatatcgg ctgttcgcgg aaaaatctgc ttggtctctt
    41161 ctggataaga agacgtcgca atatccacat cgtggatagg gttatggaga agggcatctc
    41221 gaacagagcc cccaacaaaa taagcctcaa agcctgcttc tttaattttt tctaatactg
    41281 gtaaagcctt ctgaaattca gaaggcattt gcgttaatct cataataagt gttctaatcc
    41341 atagacaagc tcatgacgct tgacaacttc tttaattccc aaattgactc ctgtcatgaa
    41401 ggagatgcga tcataggagt catgacggag ggtcaaccct tctccctgat tgccaaagat
    41461 gacttcctga tgggctacca aacctggcaa acgaactgag tggatgcgca taccatcaaa
    41521 gtcagcacca cgagcaccag caatcagctc ttcctcatct gctgcgcctt gctgaatgga
    41581 ctctcgaacc tctgccatca actcagctgt tttaatggct gttccactcg gagcatcctt
    41641 tttcttgtca tgatggagct caataatctc cacatttggg aaatatttgg cagcctgcgt
    41701 cgcaaattgc atgagtaaga cagcacccaa ggcaaagtta ggggcaatca ggccacccaa
    41761 gtcttgggca cgagaaaatt cttttagctc tgcaatttct tcactcgtga aaccagtcgt
    41821 tccaactact ggagcaaagc cattttcaag agcaaaacgt gtattttcgt aggcaacagc
    41881 tggagtagta aaatctaccc agacatccgc ttcaaaacca gctaaatcag ccttatcctt
    41941 gaaaacagga ataccctgcc attctgactc agactcaaaa ggatccaaaa ctgccaccaa
    42001 gtccaagtct ggatcagtca ataccatctg acaagcagcc tggcccatct ttcccttaaa
    42061 accggcaata attacccgaa tactcatctc tactcctgtc taagatacaa agtccgtaag
    42121 aacacaaagt gaaaatagga attccaatca agaagtgtct acttcttgga agaactatct
    42181 ttttcacaca gggttccagg cgtgttcaat tatcaagata caaaggacct tagctgcccc
    42241 tgaaaaatag ggaatggcac tgactttcca cgaaaggcaa gacaggcatc ttttttcaag
    42301 aggcaggtag tccgtgttca atttctaaga ttaactagcc tagaagtgcc aactaaatca
    42361 ctggaatata acctagagca atacttcctg ctcctaggtg cgttccaatg acactaccaa
    42421 atgtagcaag tgaaacatcc gaacccaagc caaaatcaag caaatgctga cgcaattctt
    42481 cagccttttc aggagcattc ccatgaatga caatgacccg gtattgacct gaagccgttg
    42541 tttccttgat aatttcaatt aagcgtttgg tggccttctt ttcagtacga actttttcgt
    42601 aaacttcaat cacaccttga tcgttaaaat aaaggattgg cttaatgcta agcaaattgc
    42661 ccaaaatggc agccccattt gaaaggcgtc caccttttac caaatgatcc aagtcatcta
    42721 ccatgataaa ggctgacgta cggctgattt gaatggctag cttatcctga atgctggcaa
    42781 aatcatcgcc ctgatcacgc caattaaaga cgctttcaac catgatgcct aggggagcac
    42841 ttgtaatcaa agtgtctggg aaagcaatgg ttaagccctc atagtcatcg accatatact
    42901 ggatattttg gtaaaaacct gaaattccag aagataggaa aagccccaag gcatgtgtat
    42961 agccttgttc tttgagcgaa gttaagattt catctaactt ggcaatactt ggttgactgg
    43021 tcttaggcaa ttcagaagcc tgagccattt tttggtaaaa ttcctcagca gacagattga
    43081 tgccttcgac atattcctca ccatcaatat tgacaggaat atccaagaca aacaagtctt
    43141 ctctttgcaa ggtctcttca ctgagataag cagaggaatc tgtgaaaaca gctaatttca
    43201 tattagaact ccaaattaat tcctggtaag tctaatgcaa tttcagtcac ttcgtaagtc
    43261 aaacgattga gcatgttcaa acatggacga gccaaggttt ccacctcttc ttggttcaat
    43321 tcacttggtt cattgacaat acggccatcg atatggttta cttgtgagat tgttccacta
    43381 atgacaaact tatcaaatac aatcataaag ctcaagatga caatcaagga agtcacttga
    43441 ttttcttggt catgttggag caattggaaa ttcacatcca ccttggtttc aggagctcca
    43501 ttttcatttt cccattcaaa attacgcgca tcaaaatgat actgactaac aaattcttgt
    43561 tcacgtttaa gattcatgtc tttctccatc ggctacaata ttataagcta ttgtaccata
    43621 attttttatt ttcatctagt tttctaggat ttagtcaatc ccaatttcag cacgaactac
    43681 atctgtgatg gtatcaacat agtagtctac ttcttctgtt gtaggcgctt ctgccataac
    43741 acgcaagagg ggttctgttc cacttggacg aacaaggata cggccgttcc ccgccatttc
    43801 ttcttccatc ttctcgatga tggccttgat agctggcact tccatggcct tttccttcat
    43861 gacgttttcc actcggatat taactaattt ttgtggataa atcgttactt ctgccgccaa
    43921 ctctgataag ctcttaccag tttccttcat gattttagtc aattgaactg ctgataattg
    43981 accatcacct gtggtattgt aatccatcaa gataacgtga ccagactgtt caccaccaag
    44041 gttgtaacct gattttctca tttcttcaac aacgtagcgg tcaccaactg cagtaactgc
    44101 cttgttaata ccttcgcgat tcaaggcctt gtggaaacca aggttagaca taacagttgt
    44161 cacaattgta ttttgagcca attgtccttt ttcagaaagg tattttccga tgatgtacat
    44221 aatcttgtca ccatcgacga tgtcaccatt ctcatcaaca gcaatcaagc ggtcactgtc
    44281 tccatcaaag gccaaaccaa tagctgaccc actttctttg accacttctt gaagggcttc
    44341 tggatgtgtt gaaccaacat taaggttgat gttaagaccg tctggtgttt ccccgataac
    44401 cgtcaattgg gcaccaaggt ctgcaaagat ttgacgggca ctggtagaag ctgctccatt
    44461 agctgtatcc aaggcaacct tcattccatc aagaggagtt ccagttgaaa caaggtatcc
    44521 ttcatactta cgcaagcctt ctggataatc taccaaaatt cctaagcctt ctgcacttgg
    44581 acgaggaaga gtgtcttcct cagcatctag caaggcttca atttctgctt ctttttcatc
    44641 atctagtttg aagccatcac cgccaaagaa cttgattccg ttatcaagag ctggattgtg
    44701 gctagcagaa atcatgacac cggcacttgc tccttcagtt tcaaccaagt aagctactgc
    44761 tggtgttgca aggacaccaa gtttgtatac gtgaatccct actgaaagga gacctgccac
    44821 caaggccgat tccagcattt cccctgaaat acgtgtgtca cgtcctacaa agactttcgg
    44881 cgcttccgtt tcatgttgac taagaacata gcctccaaaa cgtcctagtt taaaggctaa
    44941 ttctggtgtt agttctaggt tagcttctcc acggactcca tcagtcccaa aatatttacc
    45001 cattgttata aaatcctttt ctatttttaa ttcgtttttg aactagttgc tttcgttgac
    45061 gaagatgtct ccgatgaact gcttgtactt gaatttgatg tgcttgaact tggtgctact
    45121 ggttttgtag tcaccttcat tattgtatca aacggagtga taactgccgg taagacaaca
    45181 ccattgcggt cgattgcctg caaaggtact gaaccactgt aattacctgt tatgcgttcg
    45241 ctagttggca agacagcgat aatcttatca attctatcca atgtctcttg gtcactcgta
    45301 atagacgctt ctttatctga caccatgaca ttttcaattt gtacccgact atcaatttga
    45361 ctagggtcaa tctctggtac aatctttacc ttatccttct gagccttctt accaatcttg
    45421 actgtaattt tttgcggagt cgccacagcg gtcagcccat tgggtaaatc ttcaatgctc
    45481 aaaggaactt caattgttcc aacaccggca tctgttaggt cagcagtaac cttgaattta
    45541 cgtgtacttt cttgcatttc actagctagc gataggcgat ttgcaccagt caagaccact
    45601 gatacttctg aagcaaaacc gctaataaaa tacttatcac tattatagcg tatgtcaata
    45661 gggacatttg ttactgtatt agtataggtt tccgttttta cctgcctagc actggtactg
    45721 ttttgaaaat tcgtcgccgt agcatagaca aataagacac aagcaaaaaa gagtgaggat
    45781 atgatatata aactattttt tttcatgttt ccatcctcct agcaatcgtt ctttaaaact
    45841 aagacccact tcctcttttg gaagtaagat ttcacgtaat tctgtttcaa attcatcaag
    45901 tgttaggttg tgcttaaacc ttccattata ggttatcgaa attcctcccg tttcctctga
    45961 tacgacaaaa gtcaaagcat ctgagacttc tgataaaccg atagccgccc ggtgtctggt
    46021 cccaaattcc ttggaaatcc ctgtgttttt tgtcaagggc agataggcag acgtcacagc
    46081 gatacgttct tctttgatga tcaccgcacc atcatgtagg ggagtgttgg gaataaaaat
    46141 gttaatgaga agttctgcag aaatcttagc atccaaggga attcctgtcg aaatatactc
    46201 ctgcaaggta cgtacacgct gaatagcaac caaggccccg attttacgag gactcatgta
    46261 ttcaacagac ttaacaaagg cacgaatcat ctgttcctca gcactaatag gggcattgga
    46321 aaaaaaatct gtagctcttc ccaaacgttc caaaccagtc cgaatctctg gagagaagat
    46381 aacaaccgcc gcaataaccc cataagtaat aatttgattg attaaccaag aaatcgtagt
    46441 caaaccaatc atatttgcaa ggatttgagc taaaataaac accaaaactc cacgtaccaa
    46501 aatcataatc ttggttcctg caatagcttt tgtaaaatgg tataaaatat aagcaacaat
    46561 caaaatatca atcagattga tagctatcgt ccatggactt gcaaacaaac tggtccaata
    46621 ttgcagattg gataattgtt gaaaattcat ccctgatatc ctccctatca aaacactttc
    46681 gtcctattat accattttct ggcatttttt tccctatcct agtccatttt acattgaaca
    46741 aaaatatgat aaaataaact gactagaaaa aacaaaggag aaactatgtc tcaactctat
    46801 gatattacca ttgtgggtgg tggtcctgtc gggctttttg cagcctttta tgcccaccta
    46861 cgccaagcca aggttcaaat catcgactct cttccccagc taggtggaca acctgctatt
    46921 ctctaccctg aaaaggaaat cctagacgta ccaggcttcc caaacctgac tggagaagag
    46981 ttgactaacc gcttgattga acagctaaat ggatttgata cccctattca tctcaatgaa
    47041 acggttcttg agattgacaa acaagaagaa gaatttgcca tcacaacttc taaaggaagt
    47101 cacctgacta aaacagtcat catcgctatg ggtggcggtg ccttcaaacc acgtccgctg
    47161 gaacttgaag gtgttgaggg ctatgaaaat atccactacc acgtttctaa cattcagcaa
    47221 tacgctggta agaaagtgac gattcttggt gggggagact cggctgtgga ttgggctttg
    47281 gcttttgaaa aaatcgcacc aactaccctt gttcaccgca gagataattt ccgtgccttg
    47341 gaacacagtg ttcaagcctt gcaagaatca tctgtaacca tcaagacacc attcgcccct
    47401 agccaactcc ttggaaatga aaaaacactt gataaacttg aaatcacaaa agtcaaatct
    47461 gatgaaactg aaaccattga cctagaccac ctctttgtca actatggttt caaatcttct
    47521 gtcggtaacc ttaaaaactg ggggctcgac ctcaaccgtc acaagattat cgtcaacagc
    47581 aaacaggaat ccagccaagc aggtatctat gctatcggtg actgctgcta ctatgacgga
    47641 aaaattgatc tgattgcgac aggcctcgga gaagctccaa ctgctgtcaa caacgctatc
    47701 aactacattg accctgaaca aaaagtacaa ccaaaacact ctactagttt ataaaaaaaa
    47761 ccacgagtca cataggattc gtggttttat aattcatccg ctatcttatt gatttttctg
    47821 agtctgtgat tgacaccact tttggtcaga ggggtgctga gactatctgc taactgctgg
    47881 atagagtagt ctgggtgctg aatcctcagt tgcgccactt cctgcaaatc tactggcaaa
    47941 ttttctaagc ccatgatatc tttgatttta ctgatattgt taatggtctt catgctggca
    48001 gaaactgtcc gagcgatatt agctgtctcg gcattattag cccgattgag gtcgttacgg
    48061 gtttctcgca aaatcttaac ccgctcaaaa tcatcacgtg cctgcatggc tccgattact
    48121 atcaagaagt ccataatgtc ttctgctcgc tggagatagg tcacagcccc cttcttgcgc
    48181 tcaagcacct tggcatccag taaaaactgt tggagaaggg aggcaattcc ttgcgcgtgg
    48241 tccagataaa cagaactgat ttccaactgg tacttgcctg actcagggtc acgaatgctc
    48301 ccatttgcca agaaagcgcc acagagatag gcacgacctg cttcctcatc cgataaaatc
    48361 gcctcatcaa tacctgtttc caggccaaag aaagagtctg ccaagtgcaa atcacttaac
    48421 aaatcctgca ccttttcatc tgtaaaaacg gtatagacgc gattcttgcg aagattgctc
    48481 cgttggtggt gacgaatttc agatttgatt tcatagaaat ggagaaagga ctcatagagg
    48541 tgacgggcca gtttggcatt ttctgtcaca actgacaaag tcaagcccga agtcgagaga
    48601 ccgatgctac cagacatttt gataatggca gataattcat gccagctcag atggtgttgg
    48661 cccaggattt cttcttttac tgctactgtg aaactcattt tttcacctgt ataatgcgca
    48721 tcaactcgtc cacaatcaaa tctccatcgt ggaaggcacc gccattttcc agacgaagga
    48781 agttagatga aatcacgcgc gaaacttgct tacaaagacc tacaaaatcg tgttccactt
    48841 gcactaagta ttcatcaaaa cggttggaat tcatgtattc ctgaggcact ttttcaatat
    48901 tcaccaagac agtgtcgata aaagggcgac caaggtgacg atgcaagact tccacgtggt
    48961 cgctatctgt aaagtgttcc gtctccccac gttgggtcat gatattgcag acataggcaa
    49021 tttctgcctt ggtttccaaa agagcccgcc caatttcctt aatcacgata ttgggcaaaa
    49081 tagaggtaaa gagggaacct ggccctagga caatcatgtc actttcaagg atggtctgca
    49141 ctactcgacg gctggccaga ggcgtatcat cgtttagggc attggtcaca tagacattgt
    49201 caattatgcc tcgatggtct acaatatgac tctctccagc cacttctgtc ccatcctgaa
    49261 agactgcatg aagggtcaaa ggatggtcac tggaaggata aattttccct gttgtatgga
    49321 aaaatttgct caataactgc atggcattat aggttgaacc ctgcatttct gacaagccag
    49381 caatgatgag atttcccaat ggatggccag caaaggctcc ggcatcctca gagaaccgat
    49441 actgaaagac cttctcataa aacttaggca tatccgacat ggccacaagg acattacgaa
    49501 gatcacctgg cggtgtcaac tgttgcatat tttttcggag ttcacctgaa gaaccaccat
    49561 catctgccac cgtcacgata gctgcgattt ccacatcttt ttcccgcaga ctttttagaa
    49621 tgacgggaat tccagtccct ccaccaatca ccgttatctt tggttttctc atgaacggtt
    49681 taccgtttcc tttctgcggt ctttgtcgcg atgcccttca ttaacagacc aattcttgga
    49741 taagtcctgc gccaagcgtt tagcaaatgc cacactacgg tgttgtccac ccgtacatcc
    49801 catggcaatg gtcaaaacgg acttaccttc cttttggtaa cttggcagaa tcggctcaat
    49861 caaggccaat aaatgttgat aaaagtcttc tgactcagga tggttcatga cataatcata
    49921 aacaggttca tccacacccg tttggtttct cagttctggt agataatagg gatttggcaa
    49981 gaaacggaca tcaaagacca agtccgcatc aatcgggatt ccatacttaa atccgaaaga
    50041 catgacttcg atacggaaag actgggcttg ttcttggtct gaaaactgct ctgcaagggt
    50101 tttgcgcagc tcacgtggag tgagttcagt cgtatccacc acattttggc tcatattttt
    50161 caaaggtgcc aagagttcac gttccaactt gattccatct aaaatacgac cgtctgctgc
    50221 tagtgggtga ctccgtctgg tctccttgta acgagcgacc aattccttat cagccgcatc
    50281 caaaaagagg attttgaaat ccaaaccatc ttgattttcc aactcatcca aaacagcttg
    50341 aatctctgaa aagaaagaac ggctacgcat atccactacc aaggccaact taggattgtc
    50401 ttccttaatt tcaaccagct gcaaaaactt aggcaagaga gctggcggca tattatcaat
    50461 ggtgaaataa cctagatcct cgaaggactg aatggctaca gttttccctg cgccactcat
    50521 ccctgtcaca atcaccaagt gaagttgttt ctttgtcatc tttttctcct tatatcaaaa
    50581 gaagtttggc aacaccaaac ttcaactagc ttatccaatc tctgcgatga cttcaatttc
    50641 gacttttaca tcacgaggaa gacgagctac ctccacagct gaacgagctg ggaattcctc
    50701 tttgaaggcc gtttggtaaa cctcattaaa aggaacaaag tcgttcatat cgctcaagaa
    50761 gcaagttgtt ttgacaacat ggtcaaagtc tgttcctgct tctgccaaaa tagcaccgat
    50821 gtttttcaag acttgctctg tctgttcttg gatattctct cctacaattt ccccagtttc
    50881 aggggatagg ggaacttgac cgctagcaaa caaaaggttg ccaacgattt ttccttgaac
    50941 atagggtccg atagcctttg gggccttatc tgtatgaatt gtttttgcca ttttcttttc
    51001 ctcacaattt ttctaagatt gcatcccaag cctcatccat ccctgccttg ctgacagatg
    51061 aaaagaggat gaaatcgtca cttgggtcaa agtttaattt ctttttgatt gctgattcat
    51121 gcttgttcca tttaccacga ggaatcttgt ccgccttggt cgccacaatg atgactggaa
    51181 tctcataata cttgagaaat tcgtacatct gcacatcatc tgctgacggg tcatgacgaa
    51241 ggtcaactag actgacaacc gcacggagat tttcccgagt cgttaagtac tcctcaatca
    51301 tgcaccccca cttttcacgt tcctttttag aaacacgagc atagccataa ccaggcacat
    51361 ccacaaagcg catcttgtca tcaatgttaa aaaagttcag gagctgggtt ttaccaggtt
    51421 ttcctgatgt acgggcgaga ttcttacggt tcaacatagt gttgataaag ctggatttac
    51481 caacatttga acgccctgct agggcaatct ctggcagttc atcctgcgga tagtgggact
    51541 tattagctgc actgagcaag atttcagcat tgtgtgtatt aagttccata gtcacctcta
    51601 ggctgtttct aggatcggtt tatccgttcc atctacagtt tctttagtga tgcgaaccaa
    51661 tttcacattt tcctgactcg gcacctcaaa catgacatct agcatggttt cttcgatgat
    51721 ggagcgaagt ccacgcgccc ctgtcttccg ttcgattgct ttattagcaa tctcttgaag
    51781 ggcttcgtcg tcaaattcca actcaacatc atcataagaa agcaaggttt ggtattgttt
    51841 caccaaggca tttcttggct ctttcaagat gcgaaccaag tcatcaacgg tcaattgctc
    51901 aagagccgca aaaacaggca agcgtccaat caactcaggg ataataccaa atttttgaat
    51961 gtcttcagcg atgatttctt gcatgtatga gctgttttcg tcaatcgcct tattgttttg
    52021 accaaatccg ataacttttt cacccagacg ttgtttgaca atttcttcaa taccatcaaa
    52081 agcaccaccc acgatgaaga ggatattttt tgtatccact tgaatcatct cttgttgtgg
    52141 atgtttgcgt ccaccttgag gcggcacgct agcaacagtt ccctcaataa tcttgagaag
    52201 ggcttgttgc accccttcac cagaaacatc acgtgtgata gacacattct cactcttctt
    52261 ggcaatcttg tcaatttcat ccacatagat aatgccacgc tctgcacgtt cgatgttaaa
    52321 gtcagcaacc tgcaagagtt tgaggaggat attttccacg tcctcaccca cataaccagc
    52381 ctccgtcaga gctgtcgcat ccgcaatagc aaaaggtaca ttcaagctct tagccaaggt
    52441 ctgggcaagg aaagttttcc ctgaaccagt tgggccaatc atcaaaatgt ttgacttctg
    52501 caaatctaca tcttctgact cttcgcgtgt atcgtggaaa ttgatgcgtt tgtagtggtt
    52561 ataaaccgcc actgccaagg cacgcttggc acgatcttga ccaattacat agtggttcaa
    52621 gatatggagg agttcaattg gttttggcac ctcagacaag tctgccaaga cttcctcaac
    52681 caattcttct cgaatgattt cctgagctaa ctccacgcat tcattacaaa taaaagcatt
    52741 gttgccagca attatttttt gtacttcttc ttggtttttg ccacaaaatg agcaataaac
    52801 catcatatca ttttttctat ttgtagacat gatttccttc cattctatac tgtcattcta
    52861 tctaaaataa ggtcatgtaa aaagcatgaa tactattgac cagattggta aaggcattta
    52921 accaaaggag gatagaaagc ccgtaacgct ttttacgaaa agcctgtgct cctgccagaa
    52981 agcagatgaa acacagaaaa gccgtgaata gaccaaataa actccgttcc attagacttc
    53041 ctttctcttg cggtattgga tggtaaaatc ataaggattc ttctcatctt tggcgtaaaa
    53101 tttgcttgaa actgtctcaa aaagagacaa gtcaagctct tcagggaaat aggtatctcc
    53161 ttccacccga gcatgaatgt gagtgacaat cacttcatca aggtaaggtc caaaagcctg
    53221 aaaaatttgc ttcccaccga taatgtagag attcttttct tgagcctgat accagtcaag
    53281 aacagactgg acgtcctgaa aagtagcaac cccatctatc ttttcttccg gattacgcgt
    53341 caaaatcaag gtttcccgtt ttggaagcaa gcgacgtccc atcccatcaa aggtcacacg
    53401 ccccatcaag atagcatgat tcagagttgt ttctttaaag tgctgcaatt ctgctggcaa
    53461 atgccaaggc agacgatttt ccttaccaat cacaccctct tcatcctggg cccaaatagc
    53521 tacgattttc ttagtcatgc ttccatcctt ttcactgata gtactatttt atcaaaaaac
    53581 tcaaaaaaag actggtttgg aatagcttac aaaatagaaa aaatctgtaa gaaatttcct
    53641 acagatttat ctatgtttcc ttatttctta caaaccaggt gcttgtccaa gttcggctgc
    53701 aagcatccaa attgttttat ctgtttcagt tttagcgcct gcaaagatac cgtttgtcac
    53761 atcgtcacct tcttcatcag tgacatccaa acctttttgg aaaagttctg acaagtaacg
    53821 gtagataaca agaacacgtt ccaagctttc ttcaacatta cggtattcac cagcttcttc
    53881 ttcgatttca ctattttgaa ggaactctgt caatgtagag aatgggcttc caccgagtgt
    53941 aatcaagcgt tcgctgattt catccaattg accgtcaaga gcttccatgt actcatccat
    54001 ttttggatgc catacaagga aaccacgacc atgcatatac cagtgcactt ggtgcaaagc
    54061 aacgtgagct acatacaaat cagcaacagc ttggttcaag acttcctttg tttttgccaa
    54121 tgctactggc gctgcttttg tcaatgatgt tacgtctttt actgcttctt ttttcaattc
    54181 taccattttc tttacctcat tcattatttt ttgtaaccac ttcttaatga ttactacctt
    54241 agtatactac taaggaaaac caatagcaag acaaagaact tatatgagaa aagttgcaat
    54301 agactgataa tttaagaatt ctttagaaga caaaaaagag ggttggatgc ttatagtcaa
    54361 tggaaatcca tcagcaaact aggaaactaa acccagcttg accaaagcac aagttttgag
    54421 gtcgcaggta ggactgacca agctgatgtg gtttgaagaa attccccaat actataatag
    54481 attgaaataa gatgaaacca agtcgattag gaaaggtaaa tgaatttcta aaatgtttta
    54541 ccaatcacaa ggtctttatc tatattcaat ctactatata agcttcattt ccgagcaaga
    54601 tcttgaattt actcgaggat gaactatcat aaaacaaaga aaaagagggt gctactatca
    54661 catccctctt tcaaatcatc gcttaatacc aaacgctgac atctacgcgc ccttggattc
    54721 ctttcatgta ttcagaagag gtatattgcc aacctttttc tcctgaataa taagggtttt
    54781 cccattctaa agcattcgta taggccgcta cccagtttac atgttttaaa atatctgggt
    54841 gttttaaacg cgtctgtaat aaactacgat agctatagac atacacattt tgataacccg
    54901 cctgcttcat cgtgtccatg tacttgttga tgattttaac ccaagtgtct gtatcacttg
    54961 gagctctctt gctcttattt acatattccc agttctcaac atcataatag atagggtaag
    55021 acaggttcat attgtatttc tttataagtt caatggtctg tttagcgtca ttctcagcat
    55081 cggtctcatt ttcagcatag gtatagagat agacaccata aggaattccc agacggttta
    55141 actccttaat gttatgcgcc aattccttgt cttctttacc gctataacct agacgaacaa
    55201 tgacaccatc cacctcgttc tcatcaataa cctttttcca atcattgata cgaccattgt
    55261 gctcactaat atcaatgatt ttcttagcat gttcggttcc cacttgttct tctctattat
    55321 taaagaaata gcgtttacca tctctgtgaa cccagccgac attcaaatct ttcttttctt
    55381 tgagctcacc agaggccgca aagatatagc gagtaccatc cataatcact tcgtcagtcg
    55441 ccatggcacc acttccagtc aaatagtagt tgccttgcca ctcattccga gccatatagc
    55501 cccacttctt gaaatagtac catttgccgc ccactttttg ccactcttgg ttagcataag
    55561 ttccatcgga ttttagataa aaataagcag aataggctgg atcatagagc cattcatttt
    55621 gcatcatagc tccttgacca ttcaagaaat aacttccttg ccattggctt ttagccatgt
    55681 aaccccactt cttgaagtag taccacttat ttccaatcaa ttgccattct tgatgagcat
    55741 aagccccatc tgacttgaga taaaaccaac tcttgtaatt actgtcatag atccactcgt
    55801 tttgggccat atatccacct gatttcaggt agtaatttcc atgccattca ttctgcgagt
    55861 aacgaccatc tgaattaata taaaaccagg ccttatagta gttgtcaaaa atccattcac
    55921 tttgagcttt agagccatca tcctttacat aataatcccc atcccagtgg gcagcagcat
    55981 tagtctgtac ttctgtgctc gtttgcgttt tattagaaga ctgattttgc tctgaactac
    56041 ttgaagctgt cgttgtatcc tgcgaagttt ttgctacttc agtttcattt gcagcgacat
    56101 gactagttgc caagcctagt aaacagatac ttgctaatcc aatttttatt ttcaatcttt
    56161 cctctcctat aaaaaatgta acagacatct gaatgctgtt ccacctagct tttgctactt
    56221 actgattatt ttacaaagtc aagcaaagcc aagaagcttt cagcttcaag tgacgcacca
    56281 cctacaaggg caccgtcaac gtctgggcaa gccatgtatg aagcaacatt ttcaggttta
    56341 acagaaccac cgtattgaac acgaactttg tctgcgactt cttgaccaaa gtcagcagct
    56401 acaacgtcac gaacaacttt acacattttt tgtgcatcgt cttgtgaagc tgatttacca
    56461 gtaccgatag cccagattgg ctcataagcg ataactgagg cagcaacttg ttcagcagtc
    56521 aatccagcca atgcagcaga tacttgagca cctacgaatt cagcagcttt accagcttcg
    56581 taagtttcaa gtgattcacc acaacagatg attggaagca taccgttcgc aaagattgct
    56641 tttgcttttt tgttgatatc ttcgtcagtt tcatggaagt agtcacggcg ttctgagtga
    56701 ccgataacaa cgtaatcagt accgatttct ttcaaaactt gtgggctagt ttcaccagtg
    56761 aaagcacctg cattttcaaa gtagcagttt tgagcagcaa ctttaaggtt cgagcctttt
    56821 gcaacagcaa gaacagttgt caaatcaaga gctggagcag cgatacctgc ttcaacaaga
    56881 tctgatgaag gaagttttga tgcaactgct tcaacgaatg ctttagcttc ttctggattt
    56941 ttgttcattt tccagttacc agcgataaat ggtttacgtg acatttcaca tacctctttt
    57001 ttcaatttat tttctattta ttctatcaca attatacaca gcttgcaaat cttactcgga
    57061 tttcaagcct acttgcatgg attaatcctt ccagagatcc atggcatttc tgaaatctgc
    57121 agatacctgt gtcaactgag gattgcttgc ttctctttct gctctcttgg cctcaatttg
    57181 agccacactc ttgattcctt catggcgcca gtttctcaaa attgcctgaa tgtacttcca
    57241 gtttggtttt ccattcaaaa cagcttcacg aagagcctcc ttaatcaagt cagcactggt
    57301 tccatcttcc tttagtgtct tggtcaaatc ctcaatctca aaaggcgtca acaatcgtcc
    57361 caactcctgc tggaaggttt ccaccaaatc cttgagctgg ttttgaggtg ttagctggtc
    57421 tgaacttgaa cgaactgctc caaacaggtc atccaaacgt tccaaggcca aactagcatc
    57481 aaagaacaat tcaatttcgc catttaattc gatagtacga tactggagca gtcccctttc
    57541 cgtcagatta gaaatggact ggttgacatc cgaaatttcc ttgccaatcc tttcagcaat
    57601 ctggcttggc gacatttctt ctaagcctgt cgtattttgc aaatagaaaa attgccaaac
    57661 cagaaaatcg tcgctagaag gaaagagttc cttaaaatgc aagagcaggg cactcggtaa
    57721 aaccaaggta cctgatttaa aagcgtctaa atatgtcata attcctctta taaataccca
    57781 tatgcagatg catcatcttc tatctttctc caatcaaaag gcgtctcctg atagaccgca
    57841 tggtttaccc aattactgaa aaagagggct gcagatgaag accaacaaag acaaggtacc
    57901 tgattaacat catcatcttt aaagtaattt tctggaatat gtgggtcgaa acctgcatca
    57961 cgatctcgaa aatactcttt tgccaaggta tcacggtcat actccaaatg accaaaacta
    58021 taaatttctc gtaaatcacg actggccaaa atagaaaccc caacctgagg tccttctgat
    58081 aaaatctcga gattggtctt gtttaagacc tcttccttag aaatctccgt gtgccgtgaa
    58141 tgaggggata catagctatc atcaaagcct ctaaatagaa ggtgaccctc ttttagggtg
    58201 tcctgaggat aaatacctga tagcttactg tccatctggt atttttctac accatagcgc
    58261 agataaagcc cagcctgagc cccccaacag atatgaaggg tcgaatagac atgagtctta
    58321 gaccactcaa gcatctgtct aaattcctcc caatagtcca cttcctcaaa tggtaaatgc
    58381 tcaactggag cacccgtgat gatcatccca tcaaaatact catccttgac ttcaggaaaa
    58441 gttttataga aggtctccat gtgctctgaa cgagttgttt tagaacggtg gctctccata
    58501 tagagaaaat caatatccag ttgtaggggt gtattagcca agtggcgcaa caactgggtc
    58561 tctgtgacca ttttctgtgg catgagattt aaaattaaaa tcttcaaagg acggatatct
    58621 tggtgggcag cacgttgatc atccatgaca aagatattct ctgtccgtaa aatctcaaca
    58681 gctggcaatt ttttatcaat tcgaatcggc ataaccctct cctaactgta ctctttcagg
    58741 aataattgca tatgtttgaa gacaaatctc aaacacttag tccttttatt atactgtaag
    58801 aagatatagt tttcaattat agtttttctc taactagtta tagtctattt ttatatccta
    58861 gtgtagagaa aacagcccta gggactgttt tcattaataa tgcataagaa ctttgtagtc
    58921 gtagtcacca attttttcac ggccgttcaa ttcatccaat tcaacaagga aggcacaacc
    58981 tgccataaca ccaccaagtt tttcaatcat ctcgatagtt gccttaacag ttccacctgt
    59041 cgccaaaagg tcatctacaa taagaacacg ttgacctggc ttaatggcat ccgcgtgcat
    59101 agtcaaggta tcgacaccgt actctttttc atagtcagca gaaataactt cgcgtggcaa
    59161 tttacctggc ttacgaacag gcgcaaaacc aattcccaac tcaaaggcaa ctggacaacc
    59221 cacgataaat ccacgagctt caggtcccac gatcatgtcg actttcttgt cagtagcata
    59281 ctgaacgatt tcacgaacag cgtagctata agcatttcca tcagccatca aaggactaat
    59341 atcacggaag gtaatgcctt cctttggata attttcaatt gttgcaatgt aatcttttaa
    59401 attcatcttt ttctttcttt caaagttttt tactctctat tatagcatat tttttaagaa
    59461 agaaaaaagg aaaagttaac ttcaataatt atctaacgtt ttgacgattt ataactagcc
    59521 atcgcaataa agcccaattt ctgtttattc ttagcaaaca ttttatacat agttaaaaac
    59581 tgctttctat tctccttttt acaagcattt acacaaattt tcaaagttcc tagcaaacct
    59641 tcgtcataaa tcatacccga taatttcatt aatgtcattt caccagtcaa tgctttcaca
    59701 tcacaataac ctgattctat catcacctgt tcccaaccat cttgagttaa aggacctaca
    59761 tttacatgaa ttgcttgtga taattcctgt ctgatagact ctttagcttc cttaagaagc
    59821 acatcatgtg tcaagagaag acctccaggt tttaataccc ttagatattc cattacacat
    59881 tttttcttag cttgatcggc ttgcatagtc agcatagctt catttataac aatatcaaaa
    59941 ctagcatctt gataaggaag tttcattgca tttgctcttt caaaactgat taaatgagca
    60001 acacctgccg ttccagcaaa ttttttagcc acttctaaag cttgagcatc catatcaaca
    60061 gcagttatct tgcaaccaaa acgctgtgcc aactcaattg ctgtagttcc cctattacac
    60121 gcaacctcta gtattctctt ttcttttgaa aatcctcctt ctgcaattaa ccaatctgtg
    60181 gcacgctttc cacctggacg taagcgtttt ttccccaatt ttgctaaaaa cttatgacct
    60241 gcttctgaca tttgaacacc tctgtttttt cttcattata acacaaaatg atattatctg
    60301 acaattctaa tctattattt gataaactag aatcaaaagc atacaagtca ccataactat
    60361 agcataaatt tattattacc tctctagttc gaattcaatt gctcacgtag tttacgcata
    60421 tagcttcact tgtagatggt acccacaaat aatactcaat ggaaatcaaa gagcaaacta
    60481 ggaaactagc cgtaagctgc tcaaagtaca tctttgaggt tgcagataaa actgacgaaa
    60541 tcagtaatca tacgtacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
    60601 attaaagagc atcacaatat agatgcataa tatgacttct ctagcaaaaa ggagagaagc
    60661 attttgtttc tctccctaga ttaactgata tctctccact acaattgata aagagatatc
    60721 ttttcttgta gtgctttgaa ttttatttat tttagtagat tgttttttca gtttctacat
    60781 cgaagaagtg tgctttgttc aagtcaaatc caagctcaac tgttgcacct gtttgcaagt
    60841 agtcacgagc atcaactttt gcaacaaact cgtctttacc aacttggcag taaaggtgag
    60901 attctgaacc aagcagttct gatacagaga tagtcgcttt tacaacacag tctgggaatg
    60961 tttcaaggaa agcaggttct gcattcacgt cttctggacg gataccaaag atcaattctt
    61021 ttccttcgta gcctttttca cgaagaactt tcaatgctcc ttctggcact ttcaaacgga
    61081 aaccgtcaga aacaatttcg ctaccaacca atttcacggt gatgaagttc atagctgggc
    61141 ttccgatgaa tcctgcaacg aatttgttaa ctggattttt gtaaacttct tgaggagtac
    61201 cgatttgttc tacacgtccg atagtacctg taccagcagg gttcttagta gctgacataa
    61261 taacgatacg gtctgcaagt gtcatcgctt ctgtttggtc gtgagttaca tagatagttg
    61321 tagctccgat acgacggtga attttagcga tttcagcacg cattgataca cgaagtttgg
    61381 catccaagtt tgacaaaggt tcgtccatca agaatacttt cgcatcacgg acaatcgcac
    61441 gccccatggc aacacgttga cgttgaccac ctgaaaggtc agctggttta cgttccaaga
    61501 attctttcaa tccaagtatt tcagctgctt cttgaacacg tttgttaatg tcttctttgc
    61561 tgtatttacg caatttcaaa ccgaaagcca tgttgtcata aacagtcatg tgtgggtaaa
    61621 gagcgtagtt ttggaatacc atggcgatat cacggtcttt tggagctacg tcgttgacaa
    61681 ctacgccatc gatagatgca gtaccttctg taatgtcttc aagaccagca atcatacgga
    61741 gtgtagttga tttaccacat cctgaaggtc ctacgaaaac gataaattct ttatctttga
    61801 tgttcaagtt gaaatcttca actgaatagt gttcgctgtt tggatatttt ttgtaaatat
    61861 ttttaagatt caattctacc atgaggtgaa ctccttttgt cttttgataa ttatattata
    61921 tatgaaaacg ctttatattt ctatggcaag atgaccaaaa aaataaacaa gttctgtgca
    61981 acttgcacaa aactttagag aatatcggag aatttgaaga agataatctt tattattctt
    62041 ctatagacaa aagcagaaac aaggatcagt tttcccatat ttt
//
LOCUS       DAVEHY010000009        60397 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVEHY010000009 DAVEHY010000000
VERSION     DAVEHY010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.009"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(40..993)
                     /locus_tag="VUZ44_000677"
     CDS             complement(40..993)
                     /locus_tag="VUZ44_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU0319635.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(1061..2270)
                     /gene="sstT"
                     /locus_tag="VUZ44_000678"
                     /pseudo
     CDS             complement(1061..2270)
                     /gene="sstT"
                     /locus_tag="VUZ44_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            2409..2969
                     /locus_tag="VUZ44_000679"
     CDS             2409..2969
                     /locus_tag="VUZ44_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU0319636.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            3026..3934
                     /locus_tag="VUZ44_000680"
     CDS             3026..3934
                     /locus_tag="VUZ44_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU0319637.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            3886..4476
                     /locus_tag="VUZ44_000681"
     CDS             3886..4476
                     /locus_tag="VUZ44_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU0319638.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            4479..5585
                     /gene="yqeH"
                     /locus_tag="VUZ44_000682"
     CDS             4479..5585
                     /gene="yqeH"
                     /locus_tag="VUZ44_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU0319639.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAYEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            5800..6111
                     /gene="yhbY"
                     /locus_tag="VUZ44_000683"
     CDS             5800..6111
                     /gene="yhbY"
                     /locus_tag="VUZ44_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU0319640.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            6163..6792
                     /locus_tag="VUZ44_000684"
     CDS             6163..6792
                     /locus_tag="VUZ44_000684"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU0319641.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLVPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            6792..7385
                     /gene="yqeK"
                     /locus_tag="VUZ44_000685"
     CDS             6792..7385
                     /gene="yqeK"
                     /locus_tag="VUZ44_000685"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU0319642.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPGLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRSFPGVDVAREVASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            7386..7886
                     /locus_tag="VUZ44_000686"
     CDS             7386..7886
                     /locus_tag="VUZ44_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU0319643.1"
                     /translation="MKMAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKIAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            7899..8252
                     /gene="rsfS"
                     /locus_tag="VUZ44_000687"
     CDS             7899..8252
                     /gene="rsfS"
                     /locus_tag="VUZ44_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU0319644.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            8572..9312
                     /locus_tag="VUZ44_000688"
     CDS             8572..9312
                     /locus_tag="VUZ44_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU0319645.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNVLNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFSMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            9353..11164
                     /locus_tag="VUZ44_000689"
     CDS             9353..11164
                     /locus_tag="VUZ44_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NACHT domain-containing protein"
                     /protein_id="HEU0319646.1"
                     /translation="MNIPIPFGDILEKEVITNIPKIYQKLKQIYNDLQFKTEEELGVV
                     YQEYLQFTYKKYSTVKTLLYKNEGKFLYDFYEHVYLDDNNSDLIETSNTELIFEKTSN
                     VILTGTGGIGKSMLVKHIFINQVQQATSIPIFIELKSLNESDFSENELVDFIYQEVQN
                     HHLNLEKKYFKATLEAGRYTIIFDGLDEVNPSKRSWLDKEIKEFVTLYNSNRYVLSSR
                     PSEEFIGWNQFAEYEIKKLNREQALSLIDKLNYDEKVKRRFYRELKDHLYDTHESFAS
                     IPLLLTIMLMTYEAGASIPNNLTDFYNQAFYTLYQRHDASKSGYKRELKAKLTPEEFR
                     NILAYIGLKTFFEGKVDFDRTTLDEIITKYCFKNNLELKTNDIVYDATHSACMMLQEG
                     VSLKFSHRSFQEYFAAVGVNQLDDKLQKQILIKWSEADRNNIVAHKTFMNALFKIQKE
                     RTYKNLCIPIIERMDEKYSRMGDITEKIVTCFNYFICRKDSRENKLELHFLLTKEVHF
                     YFSLQFLIFANLGIDILSISDYENIEKLESDIVSNWKINERKYYNMLNDDEKTLINKW
                     INGWYFSRHNYLKEWSIKFIEETTTQKRSLQNIIDSI"
     gene            11188..12285
                     /locus_tag="VUZ44_000690"
     CDS             11188..12285
                     /locus_tag="VUZ44_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU0319647.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDSLAFGTEEVLD
                     YQKIADLYTEQGAEMENFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGYNIKLHPIQRQGAGYHSVDKDVNFASATALRQHQRDKDFLERFMPSVALFEQA
                     SKVSWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQVRESNLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            12523..12777
                     /locus_tag="VUZ44_000691"
     CDS             12523..12777
                     /locus_tag="VUZ44_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU0319648.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            12781..13035
                     /locus_tag="VUZ44_000692"
     CDS             12781..13035
                     /locus_tag="VUZ44_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEU0319649.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            13226..14839
                     /locus_tag="VUZ44_000693"
     CDS             13226..14839
                     /locus_tag="VUZ44_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU0319650.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            14969..15595
                     /gene="gmk"
                     /locus_tag="VUZ44_000694"
     CDS             14969..15595
                     /gene="gmk"
                     /locus_tag="VUZ44_000694"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU0319651.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            15620..15934
                     /locus_tag="VUZ44_000695"
     CDS             15620..15934
                     /locus_tag="VUZ44_000695"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU0319652.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            16000..18396
                     /locus_tag="VUZ44_000696"
     CDS             16000..18396
                     /locus_tag="VUZ44_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU0319653.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRTYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            18409..19344
                     /locus_tag="VUZ44_000697"
     CDS             18409..19344
                     /locus_tag="VUZ44_000697"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU0319654.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEVLPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            19337..20650
                     /gene="rsmB"
                     /locus_tag="VUZ44_000698"
     CDS             19337..20650
                     /gene="rsmB"
                     /locus_tag="VUZ44_000698"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU0319655.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            20665..21405
                     /locus_tag="VUZ44_000699"
     CDS             20665..21405
                     /locus_tag="VUZ44_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU0319656.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            21402..23381
                     /gene="pknB"
                     /locus_tag="VUZ44_000700"
     CDS             21402..23381
                     /gene="pknB"
                     /locus_tag="VUZ44_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU0319657.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            23496..24254
                     /locus_tag="VUZ44_000701"
     CDS             23496..24254
                     /locus_tag="VUZ44_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU0319658.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            24256..24705
                     /locus_tag="VUZ44_000702"
     CDS             24256..24705
                     /locus_tag="VUZ44_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU0319659.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            24767..25393
                     /locus_tag="VUZ44_000703"
                     /pseudo
     CDS             24767..25393
                     /locus_tag="VUZ44_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            25461..25709
                     /locus_tag="VUZ44_000704"
     CDS             25461..25709
                     /locus_tag="VUZ44_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319660.1"
                     /translation="MVSSSSSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            25840..27012
                     /locus_tag="VUZ44_000705"
     CDS             25840..27012
                     /locus_tag="VUZ44_000705"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU0319661.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            27012..28286
                     /locus_tag="VUZ44_000706"
     CDS             27012..28286
                     /locus_tag="VUZ44_000706"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU0319662.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQIANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMAILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(28322..29287)
                     /locus_tag="VUZ44_000707"
     CDS             complement(28322..29287)
                     /locus_tag="VUZ44_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU0319663.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTQEKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(29268..30722)
                     /locus_tag="VUZ44_000708"
     CDS             complement(29268..30722)
                     /locus_tag="VUZ44_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU0319664.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWVQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAINNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRVLAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNSQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31099..32982
                     /locus_tag="VUZ44_000709"
     CDS             31099..32982
                     /locus_tag="VUZ44_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU0319665.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            33131..34018
                     /locus_tag="VUZ44_000710"
     CDS             33131..34018
                     /locus_tag="VUZ44_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU0319666.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(34338..34955)
                     /locus_tag="VUZ44_000711"
     CDS             complement(34338..34955)
                     /locus_tag="VUZ44_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU0319667.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(35370..35558)
                     /locus_tag="VUZ44_000712"
                     /pseudo
     CDS             complement(35370..35558)
                     /locus_tag="VUZ44_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(36068..36148)
                     /locus_tag="VUZ44_000713"
                     /pseudo
     CDS             complement(36068..36148)
                     /locus_tag="VUZ44_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            36264..37157
                     /locus_tag="VUZ44_000714"
     CDS             36264..37157
                     /locus_tag="VUZ44_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319668.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            37154..38353
                     /locus_tag="VUZ44_000715"
     CDS             37154..38353
                     /locus_tag="VUZ44_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0319669.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFLLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(38706..39473)
                     /locus_tag="VUZ44_000716"
     CDS             complement(38706..39473)
                     /locus_tag="VUZ44_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319670.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(39490..40185)
                     /locus_tag="VUZ44_000717"
     CDS             complement(39490..40185)
                     /locus_tag="VUZ44_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319671.1"
                     /translation="MSLLVFENVSKSYGAAPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(40190..40555)
                     /locus_tag="VUZ44_000718"
     CDS             complement(40190..40555)
                     /locus_tag="VUZ44_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU0319672.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            40695..41168
                     /gene="nrdR"
                     /locus_tag="VUZ44_000719"
     CDS             40695..41168
                     /gene="nrdR"
                     /locus_tag="VUZ44_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU0319673.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            41169..42338
                     /locus_tag="VUZ44_000720"
     CDS             41169..42338
                     /locus_tag="VUZ44_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU0319674.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            42339..43235
                     /gene="dnaI"
                     /locus_tag="VUZ44_000721"
     CDS             42339..43235
                     /gene="dnaI"
                     /locus_tag="VUZ44_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU0319675.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            43232..43945
                     /locus_tag="VUZ44_000722"
     CDS             43232..43945
                     /locus_tag="VUZ44_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU0319676.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            43959..45269
                     /gene="der"
                     /locus_tag="VUZ44_000723"
     CDS             43959..45269
                     /gene="der"
                     /locus_tag="VUZ44_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU0319677.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            45357..45692
                     /locus_tag="VUZ44_000724"
     CDS             45357..45692
                     /locus_tag="VUZ44_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319678.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            45832..46182
                     /locus_tag="VUZ44_000725"
     CDS             45832..46182
                     /locus_tag="VUZ44_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319679.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(46414..47265)
                     /locus_tag="VUZ44_000726"
     CDS             complement(46414..47265)
                     /locus_tag="VUZ44_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0319680.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            47592..47984
                     /locus_tag="VUZ44_000727"
     CDS             47592..47984
                     /locus_tag="VUZ44_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319681.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            48006..48797
                     /locus_tag="VUZ44_000728"
     CDS             48006..48797
                     /locus_tag="VUZ44_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319682.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            48790..49431
                     /locus_tag="VUZ44_000729"
     CDS             48790..49431
                     /locus_tag="VUZ44_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319683.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLVFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            49435..50067
                     /locus_tag="VUZ44_000730"
     CDS             49435..50067
                     /locus_tag="VUZ44_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU0319684.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            50095..50382
                     /locus_tag="VUZ44_000731"
     CDS             50095..50382
                     /locus_tag="VUZ44_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319685.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            50528..53041
                     /gene="secA"
                     /locus_tag="VUZ44_000732"
     CDS             50528..53041
                     /gene="secA"
                     /locus_tag="VUZ44_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU0319686.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            53122..54153
                     /locus_tag="VUZ44_000733"
     CDS             53122..54153
                     /locus_tag="VUZ44_000733"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU0319687.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            54155..55186
                     /locus_tag="VUZ44_000734"
     CDS             54155..55186
                     /locus_tag="VUZ44_000734"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU0319688.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            55225..55593
                     /locus_tag="VUZ44_000735"
     CDS             55225..55593
                     /locus_tag="VUZ44_000735"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU0319689.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            55583..56686
                     /locus_tag="VUZ44_000736"
     CDS             55583..56686
                     /locus_tag="VUZ44_000736"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU0319690.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            56705..58720
                     /gene="recG"
                     /locus_tag="VUZ44_000737"
     CDS             56705..58720
                     /gene="recG"
                     /locus_tag="VUZ44_000737"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU0319691.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            59037..60017
                     /locus_tag="VUZ44_000738"
     CDS             59037..60017
                     /locus_tag="VUZ44_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU0319692.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT        18164 a        11391 c        13579 g        17263 t
ORIGIN      
        1 tatatacagc aaggcgacgc tgacgtggtt tgaagagtat tactgtctat atttttggta
       61 aaaatcaact tttacttgga tgaaggtttt ggcttcacgt aggagttgaa gaagggtggc
      121 gcgggtttca aattcttctc ttgtcttggg cagactgcgg ttccggaaga cttccagata
      181 acgttcaatt tcatctagca aatcagaagc aggattggtc tggctcagtt gacctgcaat
      241 ttttgaaaag agttgcgcta agatcaggct ttcactggcg gcaaggtgac aagtgttaat
      301 ctgttgggcc atgtttctca ggatacgact ttgtcgctgt ctcatctcaa agtagtggat
      361 atggtagtct gtctggtgaa agaggtggtc agagtgatcc aaatagacca gtctgagggc
      421 ttctttcaaa agcgtgtcta attctgctac cagctgtgct cggttgcgtc cgtctcctct
      481 ggataaatag tatttgaagc gctggaggat atcttttaac ttttcttcca ccagcgtgtg
      541 gtagtgctgg atttcctctt ctcgtgaagg catatagaga ttaacaagca aggcaaatcc
      601 tgtaccaata gcaaagagaa ggaattcatt gactagaagg tctggagagg ttgactcttg
      661 aaccaagaga tggctaacca aaacagtgct tggtgtgatg ccaatttccc agcccatctt
      721 gtaggctaaa ggaacgtaga aggccagata gaggccgaga ctccagatat gaaatccgct
      781 caagtgaaaa gctagaacac cgatagccag agctagaagc atagaaaaaa gacgattgcg
      841 agccagtttt aaagtacttc tacgcgtatc agataggctc aagagagcga taattccagc
      901 cgaaactgct gacgaaagat tgagaaaata agcaagcagg caggcaagac aggtagctaa
      961 gatgagcttg gtcgtacgtt ggctaataga cataagaatt tcctaataag ttagaataaa
     1021 agcgtaaaag acaagacatg agcaggcttg ccttgatgag ttatttttta cgggttgctg
     1081 cgtattcggc aacggcggta aagaggacat ctgtagaaga gttaagggct gtttcacatg
     1141 agtcttggat gacaccaatc acaaaaccaa ccccaacaac ttgtatggca atatcgttag
     1201 aaataccgaa aaggctacaa gcaactggga taagaaggag ggaacctccg gcaatacctg
     1261 aagcaccaca ggctgagata gctgctacca cactgaggac aaaggctgtg gcaaagtcaa
     1321 caggaattcc aagagtgtta actgtaacaa gggtcaaaag gttaatggta atcgctactc
     1381 cagccatatt gatagtagaa ccgagtggga tagaaacaga ataggtatct gggttgagtc
     1441 caaggtcatg gcagagtttc atgttgacag gaatgttagt cgcagaacta cgagtgaaaa
     1501 aggctgtcac accgctgaca cggaggcagt tccaaactag agggtaagga ttgcgtctca
     1561 taaagaagaa ggcaatcaaa gggttgacca caggggcaac aaaaagcata gtcgttacta
     1621 atggaaccaa taaaatacca tagttggcaa ggcttccgac tcccttgtca gaaatggttt
     1681 taaaaacaag accaaggatt ccaaatggag ccagattgat gatccattcg acaattttag
     1741 aagtcacgtc agcgatagtt tttagcaatt ctttactatt tttactggct tctctcatag
     1801 cgattccaaa aatgactgcc caagataaga ttccaatata gttagcagta aacagggcgt
     1861 tgactgggtt gtcaaccagt ttgagcaaga ggttgctgag gacctgccca atcccatctg
     1921 gtggtgcaat ttcagtattg gcactattta gggtaatttc aatagggacg atgaaacttg
     1981 ctagtacagc tacaagagca gcggcgaaag tccctatcat aggatataca agaaaacaac
     2041 agttttcata ttgctatctt gtcccttttg atgttgggaa agggcattgg caacgagggc
     2101 aaagactagg ataggagcaa cagcttttag acctccaacg aataaatccc cgagtagccc
     2161 aatccctgag agattaggaa gggtcagtcc taggattccc cataaagcat accaatcaag
     2221 atacgcttga caaggcttgc cttattccaa gcatgaatga ttcttttcat aataatctcc
     2281 tttttgtgta gtgattatga ttatagtata aatgatagac aaaatcaaga attttctgtc
     2341 tattttttga atatttatgg agaatgagac tgatgaaaat atggtataat gaaataaagg
     2401 agttttatat gcaaaaattt attcaggctt atattgaaaa gctagatgtg acaaccatta
     2461 tcgagaatat tctaaccaag gtcatttctc ttttactgct tttgattgta ttttatattg
     2521 ctaaaaaaat gcttcatacc atggtgcaga gaattgtcaa accttctcta aaaatgtctc
     2581 gtcatgatgt cggacgccaa aaaaccatct cacgtttact agaaaatgtg tttaattata
     2641 cgctatattt ctttttactc tactgcattt tgtcgatttt aggtttgcca gtttctagtt
     2701 tgctggctgg agctggtatt gctggggtag cgattggtat gggagcccaa ggctttctat
     2761 ctgatgtcat caatggcttt ttcatcctct ttgaacgtca actggatgtg ggagatgagg
     2821 tcgttctgac aaatggaccg attactgtat cgggtaaggt tgtcagtgtg ggaattcgta
     2881 cgacacagct tcgtagcgag gagcaagccc ttcactttgt ccctaaccga aatatcacag
     2941 ttgttagcaa tttctcacgc acagactaga cctgttattt taagtaattt gtggtacaat
     3001 agagggagtt taataaggag aaaagatggt tttagaaaag cagttgggca atggttgtac
     3061 ctggatagac ctagacctag gaaagttgaa taaactagaa gacctttctg aaatttacgg
     3121 tttggacaag gaaaccattg aatacgcact ggatagaaac gagcgcgccc acatggacta
     3181 ccaccgtgaa agtgggacgg ttacctttat ctataatgtc ctagacgtaa aaaaggacaa
     3241 ggcctactat gagacttttc ccatgacctt tatcgtcgag catcgtcgcc tgattaccat
     3301 tagtaatacc aagaacgcct atgtcattga acagatgact cgttatctgg agaaccatga
     3361 cacgctttcg atttataagt ttctctttgc cagtctggaa atcatcagca atgcctacta
     3421 tcctgtcatt gagcagatgg acaagagtag ggatgaggtc aatgacctct tgcgccagcg
     3481 aactaccaag aaaaacctct ttgccctgtc tgatttggag actggtatgg tttatctgac
     3541 ggcagctgcc aaacaaaatc ggattttgtt agagcatatt caaggtcatg ccttgtatcg
     3601 tagttttgat gagattgaga gagaacagtt tgatgatgcc atgattgagg ctcatcagct
     3661 ggtatccatg acagacctaa tctctcagat tttacagcag ctttcagcct cttacaacaa
     3721 tattctaaac aataatctga atgacaattt gacaaccttg actatcattt cagtcttgct
     3781 agctgttttg gcagtcgtga caggcttttt cggaatgaat gttcccttac ctttaacaga
     3841 tgagccccat gcttggctct atatcagttt ggctagtgca ggtttgtgga ttgttttatc
     3901 cttgttacta aggaaaattg cgaaaaaaag ttaagaaaag gagccagaat ggcgattgaa
     3961 aattatatac cagattttgc cgtggaagca gtctatgatc tgacagtccc aagcctgcag
     4021 gcgcagggaa tcaaggctgt tttggtcgat ttggataata ccctcattgc ttggaacaac
     4081 cctgatggaa cgccagagat gaagcaatgg ctacatgacc ttcgggacgc gggtattggc
     4141 attatcgtag tgtcaaataa caccaaaaaa cgcgttcaac gagcagttga gaaatttggg
     4201 attgattacg tttactgggc cttgaagccc ttcacatttg gtattgaccg tgccatgaag
     4261 gaattccact atgacaaaaa ggaagtagtc atggttggcg accagctcat gacagatata
     4321 cgagcagccc accgtgcagg gattcggtca attttagtca aacccttggt ccaacatgac
     4381 tcaatcaaaa cgcagattaa ccgaactcgt gagcgtcgtg ttatgagaaa aatcactgaa
     4441 aagtacggac cgattacata taaaaaagga atttaactat ggaagaaatt ctctgtattg
     4501 gttgtggagc aaccattcag acgacagata aagctggtct tggttttacc ccccagtcgg
     4561 cacttgaaaa aggtttggag actggcgaag tctattgcca acgctgtttc cgtctccgcc
     4621 actacaatga aatcacagat gtccagttga cgaacgatga tttcctcaag ctcttgcacg
     4681 aggtgggaga cagtgatgct ttagtggtca atgtcattga tatctttgat tttaatggat
     4741 ctgtcatccc aggtttacca cgtttcgtct cgggcaatga tgtcctcttg gtaggaaata
     4801 aaaaagatat ccttcctaag tcagttaagt ctggtaagat tagccagtgg ctcatgaaac
     4861 gtgcctatga agaaggtctt cgtccagtcg atgtggtcct aacttcagca caaaataaac
     4921 atgccattaa ggaagtcatt gacaagattg aacactaccg taagggccgc gatgtctatg
     4981 tggtcggtgt gaccaacgtt ggaaaatcaa ctctaatcaa tgctattatc caagaaatca
     5041 cgggtgatca gaatgtcatc actacttcac gcttcccagg gacaaccttg gacaaaatag
     5101 agattccgct tgacgacgga tcttatattt acgatacgcc gggaattatc caccgccacc
     5161 agatggctca ctacttgacg gccaaaaacc tcaagtatgt cagtcctaaa aaggaaatca
     5221 agcctaagac ctatcagctt aatcctgagc aaaccctatt tttaggtggt ttgggacgct
     5281 ttgactttat agcaggagaa aagcaaggat ttactgcttt ctttgataat gaactcaaac
     5341 tccatcgtag caagcttgaa ggagctagtg ctttctacga taagcacctg ggaactcttc
     5401 tgacaccacc aaatagcaag gaaaaagaag atttcccaag gctagtccag catgtcttta
     5461 ccattaaaga taagacagac ctagtcatct caggcctagg ctggattcgt gtaacaggca
     5521 cagcaaaagt cgccgtctgg gcaccagaag gcgtcgccgt cgttacacga aaagcaatta
     5581 tttaagcaca gaaaggaaag ggttgtctga atttgggcga gcaaggcgag ccccatagag
     5641 aatacttttc gctgtggtgt aagttggtac aagtgattgt accaactgcg gaaaatttga
     5701 gaccttaggc tcaaatttta gtcatgaaag tccgaaggac tttgctgacg tccgtcacca
     5761 cttcagaaaa gtataaaaag aaactctttt aaagaaatta tgtcattaac atcaaaacaa
     5821 cgtgccttcc tcaacagcca ggcacacacc ctcaaaccta tcatccaaat cgggaaaaat
     5881 ggactcaacg accaaatcaa aaccagcgtc cgtcaagctc ttgatgcgcg tgaattaatc
     5941 aaggttactc tcttacaaaa cacagatgaa aacatccacg aagtagctga aattttggaa
     6001 gaagaaatcg gtgtggatac agtccaaaaa ataggacgca tcttgatttt gtttaaacaa
     6061 tctagcaaga aagaaaatcg caagatttct aagaaagtca aagaaatcta agaccgaaac
     6121 tccaaataac tgtttttata gagaaataaa ggggactagc ctatgacaat cgaactattg
     6181 actcccttta ccaaggtaga gttggagcca gaaatcaagg agaaaaaacg caaacaagtt
     6241 gggattttag gggggaattt taaccctgtt cacaatgccc atctcattgt tgcggatcaa
     6301 gtacggcaac agttgggact ggatcaagtt cttctcgtgc ctgaatacca acctcctcac
     6361 gttgataaaa aggaaaccat ccctgaacac catcgtctca agatgcttga gttggcaatt
     6421 gaggggattg acggcctagt cattgaaacc attgagttgg agcgcaaggg tatttcctac
     6481 acctacgaca ccatgaaaat cttgacagag caacatccag atacggatta ttactttatc
     6541 atcggcgccg acatggttga ctatctgcct aagtggtacc gaattgatga actggttgac
     6601 atggttcagt ttgtgggggt tcagcgtcca cgctacaagg cagggacttc ctatccagtt
     6661 atctgggtgg acgtaccgct catggatatc tcgtccagca tggtgcggga cttcattgcc
     6721 caaggtcgga aacccaactt tctcctacct cagccagtgc tagactacat cgagaaggag
     6781 gggctctact gatgtcctat caagactata tcaactgctc ccgtgaggcc ttgttggaaa
     6841 aaatggcaga gcttctacct gagaaacgtc taacccattg tctaggtgtg gagcgtgccg
     6901 ctatggaatt agctcagcgc tttggtgtag atgttgagaa agcaagtcta gcaggtcttc
     6961 ttcatgacta tgctaaaaag ttgtcagatc aggaatttct agacttgatt gaccgttacc
     7021 agctagaccc tggcctcaaa aactggggca ataatgtctg gcatggtatg gtcggaattt
     7081 acaaaattca ggaagatttg gatttgcatg attcagaaat cctgcgagcc attgaagtcc
     7141 atacagtcgg tgctggtcag atgacagacc tagataaggt tgtctatgta gcagactata
     7201 tcgagcacaa tcgatccttt cctggagtag atgtggcgcg tgaggttgca agtctatcgc
     7261 tcaataaggc ggtggcctac gaaacagctc gtaccgtgga gtatctagct catcagggat
     7321 tccccatcta tccccaaacc cttgaaacct ataacgcctt tgtgcactat ttgaaagagg
     7381 actaaatgaa gatggctttt ataatcattg atgttcagaa tgttttagta gaaactgggt
     7441 tccagacaaa aagtctattg gaaaaaattt cttatttaca aaaccaggct agaagcaaga
     7501 atattgaaat tatctatgtt caacatattg agaactctga agctcaaaca tcagaagatt
     7561 ggcagttatc tgcgctttta aatcgaaaac ctgctgaaaa ggtctttcag aagaaatata
     7621 acagtatttt caaagaaact ggcttaaaag aatacttgga taagcagggg attgaaaaat
     7681 tagttttatg tggtatgcag acagaatatt gtgtggatac ctctgtcaag attgcctttg
     7741 aatatggcta tcagcttatt gttccagaag gtgctgtcac aacctttgat ggggatgaca
     7801 ttccagcaga aacgattaat gaattttatg aggacatttg ggaggagcgc tttgcagatg
     7861 tcctagatta caaacatatt ttctaaaaag aggattaaat gaacgaaaaa gaattactag
     7921 aactagtcgt gaaagcggct gatgagaaac gtgcggagga tatcctcgca cttgatgtac
     7981 aagatttgac tagtgtgacg gactactttg tcatcactag ctcaatgaat agccgtcagc
     8041 tggacgctat cgcagctaat atccgtgaaa aagtagctca agcaggcttt aaaggtagcc
     8101 atgtcgaagg cgatgcagct ggaggctggg tcttactgga cctcggtgct gttgtcgtgc
     8161 atatcttttc agaagaaatg cgtgcccatt ataatctaga gaagctatgg catgaggcga
     8221 attcagtaga tatttcagaa gctcttgctt agaagatgaa ctcagttgta gtcaactggg
     8281 tttctttgct tattttagaa aaattgatag aaaggtaaag ggcctcgtgt ttgtttcatt
     8341 tcgaaactga acacgagcta aaagctgaga taaaaagtaa ctttctttgt atctgacgat
     8401 agggaagaaa gtttcctatg tactctttgc ttttaaggct ctttgtatct tagaaaggat
     8461 ttgaacccgt cctgtaattc tcggaaaata gatagccttc cttggagctc ggctccatcg
     8521 taaggctcct aattttctat cgaattacgg gcggacttgg tatcatgttt tatggcgact
     8581 tatgaaacct ttgcggcggt ctatgatgcg gtcatggacg atagtttata cgacaaatgg
     8641 acgaattttt ctctgcgtca tttgcctaag accaaggaga gaaagaaact cttggaattg
     8701 gcttgtggga caggaattca atcagtgcgc ttctctcagg ctggttttga tgtgactgga
     8761 cttgacttga gtgcggatat gttgaagatt gcggagaaga gagcaacttc agccaagcaa
     8821 aagattgctt ttatagaagg taatatgctg aatttgtcca aggcagggaa atacgatttt
     8881 gtcacgtgtt attcggactc tatctgctat atgcaggatg aggtggaagt aggggacgtc
     8941 tttaaggacg tgtacaatgt gctgaatgaa gagggagttt tcatctttga cgtgcactcg
     9001 acctaccaga cagatgaagt attccctggc tattcctacc atgaaaatgc ggaggatttt
     9061 tccatgcttt gggatacata tgaggacgaa gctcctcact ccatcgtgca tgagctgact
     9121 ttctttatca aggaggctga cggttccttt agtcgccacg atgaagtaca tgaggagagg
     9181 acctatgaga tcttgaccta tgatatcttg ctggaacagg ctggattcaa gtccttcaaa
     9241 ctctatgcag actttgagga taaggagcca acagaaacta gcacccgttg gttttttgtg
     9301 gcgcagaagt aaatcaaata ttgttaatct tatgcttagg aggtaaggga aaatgaatat
     9361 accaatacca tttggtgata ttcttgaaaa agaagtaatt accaatatac ctaaaattta
     9421 tcaaaagtta aagcaaattt ataacgactt acagtttaaa acagaagaag agttaggtgt
     9481 tgtttatcaa gaatatttac aatttactta taaaaaatat tccactgtaa aaacattgtt
     9541 gtataaaaat gaagggaaat ttttatatga tttctatgag catgtttatt tagatgataa
     9601 taattcagat ttaatagaaa cctctaacac agaattgatt tttgaaaaaa catctaacgt
     9661 tattttgaca ggaacgggtg ggattggtaa atcaatgctt gtaaagcata tttttatcaa
     9721 tcaagtacaa caagctacat caattccaat ttttattgaa ttaaaatcac ttaatgaatc
     9781 tgatttctca gaaaatgaat tagttgattt tatttaccaa gaggttcaaa atcatcattt
     9841 aaatttagaa aagaaatatt ttaaagcgac attagaggct ggaagatata caataatttt
     9901 tgatggttta gatgaggtta atccttcaaa acgttcttgg ttggacaaag aaattaaaga
     9961 atttgtaacg ttatacaata gcaatagata tgttttgtcg tcaagaccgt ctgaggaatt
    10021 tattggttgg aatcagtttg ctgagtatga gataaaaaaa ttaaatagag agcaagcgtt
    10081 atccttaatt gataagttga attatgatga gaaagtaaaa aggcgtttct acagagaatt
    10141 aaaggatcat ttatatgata ctcatgaatc ttttgcttct atcccactcc tattaacaat
    10201 tatgttaatg acttacgaag ctggtgcttc tattccaaat aatttaactg atttttataa
    10261 tcaggccttt tatacattgt accaaagaca tgatgcatct aaatcaggat acaaaagaga
    10321 actaaaagca aaattaactc ctgaagaatt tcgaaatata ttagcctaca ttggtttaaa
    10381 aacattcttt gaaggaaaag tagatttcga tagaactaca cttgatgaaa taattactaa
    10441 atattgtttt aaaaataacc ttgaattaaa gacgaatgat atagtttatg atgcgactca
    10501 tagtgcttgt atgatgcttc aagaaggcgt tagtttaaaa ttctctcacc gttcattcca
    10561 agaatacttt gctgcagtag gtgttaatca gctagatgat aaactccaaa aacagatact
    10621 aattaagtgg tctgaagcag ataggaataa tattgtagca cataaaactt ttatgaatgc
    10681 actttttaaa atacagaaag aaaggactta caaaaattta tgtattccaa tcatagaaag
    10741 aatggatgaa aagtatagca gaatggggga tatcacagag aaaattgtta cgtgtttcaa
    10801 ttactttatc tgtagaaaag atagtagaga aaacaaatta gaattgcact ttttactaac
    10861 aaaggaagtt cacttttatt ttagcttgca atttttaata tttgctaatc taggtattga
    10921 tatattatca ataagtgatt atgaaaatat agaaaaatta gagtctgata tagtatcaaa
    10981 ttggaagata aatgaaagaa aatattataa catgttgaac gatgatgaaa aaactttaat
    11041 aaataagtgg ataaatggct ggtattttag tagacacaat tacttaaaag aatggtcaat
    11101 taaattcatt gaggaaacaa ctactcaaaa acggagccta cagaatataa ttgactcaat
    11161 ttgatactaa agaagtagga gattactatg accatcacgg gtattatcgc ggagttcaat
    11221 ccttttcata atggacacaa atacctgctg gatcaagcgg aggggctgaa aatcgtggct
    11281 atgtcaggga atttcatgca gcgtggagaa cctgctatcg tggataagtg gacacgagcc
    11341 cagatggcgc tggaaaatgg agcggatctg gtagtggaat tgcccttttt agtcagcgtt
    11401 caggcggcag attttttcgg tcaaggggcc gtggatatct tagctcggtt gggcatagat
    11461 agcctcgctt ttgggacaga agaagttcta gattatcaaa aaatcgctga cttatacaca
    11521 gagcaggggg ctgagatgga gaattttgtg gaaaatttgc ctgactctct ttcttatccc
    11581 cagaagaccc aagccatgtg gaaggaattt gcaggtcttg atttttcagg caatacgccc
    11641 aatcatgttc ttgccctcgc ttacgccaag gcggttgctg ggtacaacat caaacttcat
    11701 ccgattcagc gtcagggggc aggctaccat tctgtggaca aggatgtgaa ctttgcttcg
    11761 gcgacagccc ttcgtcagca ccagagggac aaagatttct tagaacgatt tatgccttct
    11821 gttgccctct ttgagcaggc cagtaaggtg agctgggaag actattttcc cttgctccgc
    11881 tatcaaatct tgtcaaatcc cgacctaacc accatctatc aggtcaatca agaaatggct
    11941 gtgcgcatta aagaagctat taaaacagcc cagtctgtgg aagaattggt cgagttagtg
    12001 actaccaaac gttacaccaa ggcgcgtgtc agacgcctat tgacctatat tttggtgcag
    12061 gttagagaaa gtaacttgcc agaagcgatt catgtccttg gatttactga aaaaggcagg
    12121 caacatctca agtctttgaa aggtcaggtc agtctagtca gccgaattgg caaagaacct
    12181 tgggatgcta tgacccaaaa agcagaccag atttaccaac taggaaagcc aagtatagca
    12241 gagcaaaatt ttggaagagt gccgattaga atagaaacaa actaagtcta ccgaaaggta
    12301 ggctttttga gattttttac gaataatact cttcgaaaat caaattcaaa tcgcgtcaac
    12361 gtcgccttgc cgtactcaag tacagcctgc ggctagtttc ctagtttgct ctttgatttt
    12421 cattgagtat aaatagatag aaaagaaaat cttgtacaag ttcctgacaa tttctttctt
    12481 ttcgtgtata atagtggaaa agagctaaaa cgaggtatgg ttatggaagc agtcctttac
    12541 tcaacattcc gaaatcattt aaaggactac atgaagaagg taaatgatga atttgagcct
    12601 ttgacggtgg tcaataaaaa tccagatgag gacattgtag ttctttcaaa gagcgaatgg
    12661 gacagtattc aggaaaccct gagaatcgcc caaaataagg agttatcaga caaggttttg
    12721 cgaggaatgg cccaagtccg tgctggaagc actcaggtcc atgtgattga ggagtgatga
    12781 atgctactca agtttacaga agatgcctgg gcagattatt gctactggca aaaccaagat
    12841 aaaaaaacac taaaaagaat caataaatta atcaaggata ttcaacgcga tccatttaca
    12901 ggaataggaa aaccagagcc actcaaatat gattaccaag gagcctggtc acggcgtatt
    12961 gatgcagaaa atcgcttgat ttatatgatg gatggagata gcgtggcttt cttgtccttt
    13021 aaagatcatt actaagtcta ctgcaaagta ggctttttct caagtcttta ctaaactact
    13081 atttctaaac aacaagttta ttttggtaaa tgtattccaa attccccaaa acatattcta
    13141 ttttaggttt gtgaaaatca cttttttatg gtagaatgta aaagaatgta tgtcattcgg
    13201 aataacaata aaatgaggta aaaacatgga aatcatgtcg cttgcgattg ctgtttttgc
    13261 cgtcatcatt ggtttagtca ttggatatgt cagcatctca gctaagatga aatcatctca
    13321 ggaagctgcg gagttgatgc ttttaaatgc tgaacaagaa gcaactaatt tacgtggaca
    13381 agctgagcgt gaagcggatt tacttgttaa tgaagctaaa cgtgaaagca agtctcttaa
    13441 aaaagaagca ctattggagg ccaaagaaga agccagaaaa taccgtgaag aagtggacgc
    13501 tgaattcaaa tcagaacgtc aagaactcaa acaaatcgaa agtcgtttga cagagagagc
    13561 tactagcctt gaccgtaagg acgacaattt gacgagtaaa gaacaaacac ttgaacaaaa
    13621 agaacaaagt atttctgata gagcgaaaaa ccttgatgcg cgtgaagagc aattagagga
    13681 agtcgaaaga caaaaagaag cagaactaga gcgtattggt gctctgtctc aggcagaagc
    13741 acgagatatt atcttggctc agacagagga aaacttgacc agggagattg ccagtcgcat
    13801 tcgcgaagct gagcaagagg tcaaggaacg ttctgacaaa atggccaagg acatcttggt
    13861 tcaagctatg caacgtatcg ctggtgaata tgtagcggag tcaacaaact caacagttca
    13921 tctgccagac gatactatga agggacgcat tattggtcgt gaaggtcgta acattcgtac
    13981 ctttgaaagt ttgacagggg tcgatgtgat tatcgacgat acaccagaag tggtgacctt
    14041 gtcaggattt gatccgattc gtcgtgagat tgcccgtatg actatggaaa tgttgctcaa
    14101 agatggtcgt atacatccag ctcgtatcga agagttggtt gagaaaaacc gtcaagagat
    14161 tgacaataag attcgtgaat acggtgaggc tgctgcttat gaaattggtg cgccaaacct
    14221 tcatccagac ttgatgaaga ttatgggacg tttgcagttc cgtacttcat atggacaaaa
    14281 tgttttgcgc cattcgattg aggttgctaa gttggctggt atcatggcga gcgaacttgg
    14341 tgaaaatgcg gctcttgccc gtcgtgctgg attccttcac gatatcggga aagccattga
    14401 ccatgaggtt gaaggtagcc acgttgaaat cggtatggaa ttggcccgta agtacaagga
    14461 acccccagtt gtggtgaata cgattgctag tcaccacgga gatgttgaag ctgagagcgt
    14521 gatagcagtt atcgtcgctg cagcagatgc cttgagcgca gcccgtccag gtgctcgtag
    14581 tgagtctctt gaaagctaca tcaagcgtct ccatgatttg gaagaaattg ctaacggctt
    14641 tgaaggagtg caaactagct ttgcccttca agcaggacgt gaaattcgta tcatggtcaa
    14701 tccaggaaaa atcaaggacg acaaagtcac aatcttggct cacaaagttc gtaagaaaat
    14761 tgaaaacaat ctcgattatc caggaaatat caaggtaacc gtgattcgcg agcttcgtgc
    14821 agtagattat gctaaataaa taagaaagag cagttgaaaa attactgctt ttttgttaca
    14881 ctagatagaa agactgtaaa ggataatctg gctttttgcc attattctag agaaatgtta
    14941 tttcacagat tgactaaaag gagacacaat ggcagaccga ggcttactaa tcgttttttc
    15001 tggtccttca ggggttggaa aaggaacggt tagaagagag atttttgaga gttctgaaaa
    15061 ccaatttcaa tattctgtat cgatgacgac acgcgcacaa cgtcctggag aagtggacgg
    15121 tgttgactat ttcttccgta ctcgtgaaga atttgaagag ctgattcgtc aaggacagat
    15181 gttggaatac gcagaatatg tcggcaacta ctatggaact cctctgacct atgtcaatga
    15241 aaccttggac aagggaatcg atgttttcct tgaaattgaa gttcagggtg ctcttcaggt
    15301 caagaaaaag gttccagatg ctgtctttat cttcctgaca ccaccagatt tggatgaatt
    15361 gcaagatcgc ttggtaggtc gtggaacaga tagtgcagaa gtgattgccc aacgaatcga
    15421 aaaggccaag gaagaaattg ccctcatgcg tgagtatgat tatgcgattg tcaacgatca
    15481 ggtgccccta gctgctgaac gtgtcaaatg tgtgattgaa gcagaacact tctgtgtgga
    15541 tcgtgtcatt ggtcactatc aggagatgtt accaaaatct ccaactaccc gataaaattt
    15601 agaaaatagg tacaagcaaa tgatgttaaa accctctatt gataccttgc tcgacaaggt
    15661 tccttcaaaa tattcactcg taatcttgga agcaaaacgt gcccacgaat tggaagcagg
    15721 tgccccagca actcaaggtt tcaagtctga aaaatcaact cttcgcgctt tagaagaaat
    15781 cgaatcagga aacgttacaa ttcacccaga tccagaagga aaacgtgaag cagtgcgtcg
    15841 ccgtatcgaa gaagaaaaac gccgcaaaga agaagaagaa aagaaaatca aagagcaaat
    15901 tgctaaagaa aaagaagatg gtgaaaaaat ttaaggttgg ggggactcaa tcttattttt
    15961 tctattgcaa gaatgtactg acaaggagga ggtgagaaga tggccctagc taagattatc
    16021 gtagatgtgc ccttgatgca gacggaccag ccctatagtt acaggattcc ggaggaattt
    16081 gagggaatgc tggaagttgg gatgcgggtt catgtgcctt ttggtaaggg taatcgcctg
    16141 attcaaggga ttgttcttgg tttgaagtcc caatcagatg gagaagagat ggagcaagat
    16201 ttaaaagata ttgcagaggt gctggatttt tctcctgttc tcacgccaga acaactctgg
    16261 ctggctgagg agttacgcaa atctgtcttc tcctacaaaa tttctatcct caaggccatg
    16321 cttccaggat ttctgaattc tagctatgac aagattctct atcctctgga aggcttgagt
    16381 caggaagaac gagtgcgcct gtttggttca gaagattcgc tagccttttc ttcactagac
    16441 cttgccaagc aagctgaaat gatgcgtttg actagaaaag gcctgcttgg tctggaatat
    16501 caggcagtcg atcaaaagaa ggtcaagacc cagtcttggt atgaggttga ccatgctcaa
    16561 ttagaaggtg ttgagatttc tacacgtgcc aagaaaaagt tggaactgag agattatctg
    16621 ctgtctcatc cagagagcgc ttccttggct agcttgttag agtcctactc gcgagagcaa
    16681 gtcaacttct ttgtggatca aggtgctgtt accatagtcc aaaaggaagt tcaacgctcg
    16741 gctgcttatt ttgaaggaat tgaagcaagt agacctttgg agttaaatcc agaacaaaga
    16801 caggcgcgtg atgcggttgt gagttctatt ggcagttctc aacctccctt tctacttcaa
    16861 gggattacag gaagtgggaa gaccgaggtt tacttgcaga ttatccaagg tgccctggat
    16921 aagggcaaga cagctatttt gctggtacct gagatttcct tgactcctca gatgaccgag
    16981 cgttttatag cacgttttgg ggacaaggta gccattcttc actcaggatt atccaatggt
    17041 gaaaagtatg atgaatggcg caaggtggag cgtggcgatg cccaagttgt tgttggtgcc
    17101 agatctgcta tctttgctcc tctgaaaaat ctgggtgtca tgattattga tgaagagcat
    17161 gaagtggctt ataagcagga cagcaatccc cgttaccatg ccagagaggt agctatttta
    17221 cgggctcagt ataatcaagc aactctggta cttggatctg caacgccgag cttagagagc
    17281 cgggcgcgtg ctggcaaagg cgtctatcaa cacttacgtc taacccaacg tgccaatcct
    17341 ttggctacaa tccctgaggt tcaagtgatt gactttcgag actatatcgg acaaaatgag
    17401 acgtcaaact ttacgcctcc tttgctagag gctatccaag accgtctggt taaaaaagag
    17461 caggtggttc tcatgctcaa tcgtcgtggt tattctagct ttgtcatgtg tcgggagtgt
    17521 gggacggtgg atacttgtcc caactgcgat atttctctga ccttgcatat ggataccaag
    17581 actatgaact gccattattg tggtttctcg aaggatattc ctcaggtctg tcctaactgt
    17641 aagagccgca gtattcgtta ctatgggacg ggaactcaga aggcttatga tgagctagca
    17701 gaactctttc cccaagctcg cattctgagg atggatgtgg atacgactcg aaagaaaggc
    17761 agtcaccaag ccttgcttga ccagtttggg cgaggggaag cggatatttt acttggtact
    17821 cagatgattg caaagggttt ggattttccc aatgttaccc tagtcggagt tctaaatgcg
    17881 gatacggcct tgaatctgcc tgatttccgt tcttctgaga gaaccttcca gctcttgact
    17941 caggtggcag gtcgagcagg tcgggctgaa aaagcaggtc aagtcttgat acagtcctac
    18001 aatccgcagc actatgctat tcgatttgcc aaggatcaag attacgaagg cttttatgcc
    18061 tatgaaatgg gaatcagacg acaactcggc tatccacctt actatttcac gattggtatt
    18121 accctttctc acaagaaaga agaagaggtt ttcaaacgta cctatgaagt catgaacatt
    18181 ttgcggtcag gcttgtcaga gaccagtccc attctggggc caacgccaaa accgattgcc
    18241 cgtacccaca acctctatca ttaccagatt ttaattaaat accgtttaga agatgagctg
    18301 gggccgaccc tcaaccaggt cctggccttg actcaagaac gggaaaatag tgagctccgt
    18361 ctcagcattg accatgagcc gcagcaattt ttataagaag gagaagatat gacaaaacta
    18421 atctttatgg ggacccccga cttttcagca acagtcttaa aaggactttt gacagatgac
    18481 cgttacgaaa ttctagccgt tgtgacccag ccagaccgtg ctgttggtcg taaaaaagtt
    18541 atccaagaaa ccccagtcaa gcaggctgcc aaggaagcag gactatctat ctaccaacct
    18601 gaaaaattat ctggaagtcc agagatggaa gatcttatga agctaggagc agatggaatt
    18661 gtgactgctg cttttgggca gtttctccca agcaaactcc ttgatagcat ggactttgct
    18721 gtcaacgttc atgcctccct ccttcctaga caccgtggtg gtgcgcctat ccattatgcc
    18781 ttgattcaag gggatgagga agctggtgtg accatcatgg aaatggttaa ggaaatggat
    18841 gcaggagata tgatttctcg tcgcagcatt ccgattacag atgaggacaa tgttggcacc
    18901 ttgtttgaaa aattggcgct agttggttgt gatttgcttt tggacactct gcctgcctat
    18961 attgctggtg atatcaaacc tgaaccgcag gatacgagtc aggttacctt ctctccaaat
    19021 ataaagccaa aggaagaaaa actggactgg aacaaaacca atcgtcaact ctttaaccaa
    19081 attcgtggaa tgaacccctg gcctgttgcc catactttcc ttaagggcga ccgctttaag
    19141 atttatgaag tcctaccagt agaaggtcag ggaaatccag gtgagattct ctctatcggc
    19201 aagaaagaat tgattgtcgc aacggctgaa ggggctctat ccctcaaaca agtgcagcca
    19261 gctggtaagc ctaagatgga cattgcttcc ttcctcaatg gagttggacg tacattgact
    19321 gtaggagaac gatttggtga ctaaagtaga aacggctaga agtttagctc tagcagtgct
    19381 agaggatgtt tttgtgaatc aagcatattc aaatattgcc ttaaataaac acctcaaggg
    19441 gagtcagctc tctgcagcag acaagggctt agtgaccgag ctagtctatg gaacggtagc
    19501 ccgtaaactg actctggaat ggtacctatc ccactttatc gaagacagag accagttaga
    19561 cagctggctc tatgtccttc ttctcatgag tgcctaccaa ctccgctatt tggacaagat
    19621 tccagatcat gctgtggtca atgaagcagt ggaattagcc aaactccgta aaaaaggcag
    19681 tgaaaaattg gtcaacgctg tccttcgccg tatcttgcgt gaaggctggc cagatattgc
    19741 tagcatcaag cgaaaaaaca agcgtgactc cattgcctat tctctcccag tttggctagt
    19801 tgccaaactc aaggaagaat acggagagga gagagcaaaa gccatctttg aaagcctgtt
    19861 agtgcgaaac aaagccagta ttcgtgtaac agacctaagt cgaaaagagg aaatccaagc
    19921 cttgttggag gcgaatgatt cccttttagc aaccactggt ctggttaagg agcaggggca
    19981 ttttgcaggg cataatttgt ttgcggatgg agccattacc atccaagacg agtccagtca
    20041 gctggttgct ccgacgcttg atttacaagg tgatgagcga gtgcttgatg cctgtgcggc
    20101 tccaggtggg aaaacagccc atatagcctc ttatcttacg acaggtcagg ttactgctct
    20161 ggacttgtac gaccacaagt tggatttaat tcaagaaaat gcccaacgtc tgggagttgc
    20221 agatcgggtt caaactcaaa aattggatgc cagaaaggtg catgagtttt ttgaccagga
    20281 ttcctttgat aagattttgg tggatgctcc ttgttcagga atcggtcttt tgcgccgaaa
    20341 accagatatc aaatacaata aagaaacggc agatttcgcg tccttgcagg aaattcagtt
    20401 agaaatatta ggtagtgttt gtcaaatact aggcaaaggt ggtataataa cttatagcac
    20461 ctgcactatc gtctcagagg agaattttca agtcgttaag gcctttttag agagtcatcc
    20521 cgagttcgag caggtaaaac tagaacatga atgtaaggat atcatgaaag acggctgtat
    20581 cctcattaca cctgaattgt atggaagtga tggattcttc atcagtcaat ttcgcaagat
    20641 atcggattag gaaggaactg acacatggaa atttcattat taacagatgt tggtcagaaa
    20701 cgaacaaata accaagacta tgtcaaccac tatgtcaata gagctggacg taccatgatt
    20761 attttagctg atgggatggg aggtcatcgc gcagggaata tcgctagtga aatggcggtc
    20821 acagacctgg gtgtagcttg ggttgatacc cagattgata cagtcaatga agtgcgtgaa
    20881 tggttcgccc attacctaga aattgaaaat caaaagattc accagcttgg tcaggatgaa
    20941 gcttacagag gcatgggaac tactttggaa gtccttgcta ttattgataa tcaggctatc
    21001 tatgctcata ttggtgattc gcgtatcggc ttgattcgtg gagaagaata ccatcagttg
    21061 acgagcgatc attctttggt taatgaattg ctcaaggctg gtcaattgac accagaagag
    21121 gcagaagctc atccacaaaa aaatattatc acccagtcta ttgggcaaaa agatgaaatt
    21181 cagcctgatt ttgggacagt tatccttgag tcaggtgact atctcttgct caatagtgac
    21241 ggcttgacca acatgatttc aggcagtgag attcgtgata ttgtaaccag tgatattcct
    21301 ttagcagata aaacggagac acttgttcgt tttgctaaca atgcaggagg tttagacaac
    21361 attacggttg cccttgtttc tatgaacgag gaggatgcag aatgatccaa atcggcaaga
    21421 tttttgccgg acgctatcgg attgtcaaac agattggtcg aggaggcatg gcggatgtct
    21481 acctagccaa agacttaatc ttagatgggg aagaagtggc agtgaaggtt ctgaggacca
    21541 actaccagac ggacccgata gctgtagctc gttttcagcg tgaagcgaga gctatggcag
    21601 atctagacca tcctcatatc gttcggataa cagatattgg tgaggaagac ggtcaacagt
    21661 atcttgcaat ggagtatgtt gctggactag acctcaaacg ctatatcaag gaacattatc
    21721 ctctttctaa tgaagaagca gtccgtatca tgggacaaat tctcttggct atgcgcttgg
    21781 cccatactcg aggaattgtt cacagggact tgaaacctca aaatatcctt ttgacaccag
    21841 atgggactgc caaggtcaca gactttggga ttgctgtagc ctttgcagag acaagtctga
    21901 cccagactaa ctcgatgttg ggctcagttc attacttgtc accagagcag gcgcgtggtt
    21961 cgaaggcgac tgtgcagagt gatatctatg ccatggggat tattttctat gagatgttga
    22021 caggccatat cccttatgac ggggatagcg cggtgaccat tgccctccag catttccaga
    22081 aacccctgcc gtccgttatt gcagaaaatc catctgtacc tcaggcttta gaaaatgtta
    22141 ttatcaaggc aactgctaaa aagttgacca atcgctaccg ctcggtttca gagatgtatg
    22201 tggacttgtc tagtagcttg tcctacaatc gtagaaatga aagtaagtta atctttgatg
    22261 aaacgagcaa ggcagatacc aagaccttgc cgaaggtttc tcaaagtacc ttgacatcta
    22321 ttcctaaggt tcaagcgcag acagaacaca aatcaatcaa aaacccaagc caggctgtga
    22381 cagaggaaac ttaccaacca caagcaccga aaaaacatag atttaagatg cgttacctga
    22441 ttttgttggc cagccttgta ttggtggcag cttctcttat ttggatacta tccagaactc
    22501 ctgcaaccat tgccattcca gatgtggcag gtcagacagt tgcagaggcc aaggcaacgc
    22561 tcaaaaaagc caattttgag attggtgagg agaagacaga ggctagtgaa aaggtggaag
    22621 aagggcggat tatccgtaca gatcctggcg ctggaactgg tcgaaaagaa ggaacgaaaa
    22681 tcaatctggt tgtctcatca ggcaaacaat ccttccaaat tagtaattat gtcggccgga
    22741 aatcttctga tgttatcgcg gaattaaaag agaaaaaagt tccagataat ttgattaaaa
    22801 ttgaggaaga agagtcgaat gagagtgagg ctggaacggt cttgaagcaa agtctaccag
    22861 aaggtacgac ctatgacttg agcaaggcaa ctcaaattgt tttgacagta gctaaaaaag
    22921 ctacgacgat tcaattaggg aactatattg gacggaactc tacagaagta atctcagaac
    22981 tcaagcagaa gaaggttcct gagaatttga ttaagataga ggaagaagag tccagcgaaa
    23041 gcgaaccagg aacgattatg aaacaaagtc caggtgccgg aacgacttat gatgtgagta
    23101 aacctactca aattgtcttg acagtagcta aaaaagttac aagtgttgcc atgccgagtt
    23161 acattggttc cagcttggag tttactaaga acaatttgat tcaaattgtt gggattaagg
    23221 aagctaatat agaagttgta gaagtgacga cagcgcctgc aggtagtgta gaaggcatgg
    23281 ttgttgaaca aagtcctaga gcaggtgaaa aggtagacct aaataagact agagtcaaga
    23341 tttcaatcta caaacctaaa acaacttcag ctactcctta aaagcagatg gataatcaaa
    23401 atgagtaatc aatctttgtc atgatttcat ggcaaagatt ttttttgagt ccggatttgt
    23461 gatagaatag agggagttga taaaaggagg aaagcatgga agaatcaaaa gaattaaatg
    23521 ccgtcattga tgtgattatg ctagcgggga ctattctcct taaaagtggc tcagaaatcc
    23581 atcgtgtaga agataccatg attcgaatcg cgcattcgca ggggattgtg gattgcaatg
    23641 tccttgccat gcctgccgct atctttttct ctattgaaaa taccaatatt tcgcgcatga
    23701 agcgcgtgac ctcctcttct tataacatcg aaaaagtctg cgatgtgaac cagatttctc
    23761 gtcagctagt tggggggcag attgacttag aaacagcctt taagcaattg acggccttgc
    23821 aagctcaacc ccttccctat actaagttgc aggtaactct ggctgcgacc tttagtgctc
    23881 ctttcttttc agttatgttt agcggaaata tctacgacgc acttggggca ggagtggcga
    23941 ccttatttgg ttttgccttt tccctctatg tggaaaaatt tatccgaatt ccctttgtga
    24001 cagcctttgc tggagccttt gtctttggga taattgccca gttttgggct cgctacacag
    24061 gttttccttc aacggcagat ttgattatag ctggtgcggt catgccgttt gtaccaggta
    24121 ttgccttgac caatgcggtc cgtgatatta tgaccaacca cataaactct ggtatgagta
    24181 agatgtttga atccctgctc attaccctcg ctttaggggc aggaacttct gtcgccttgg
    24241 tattgatgaa ctaatatgac actaacaacc tttttattac aagcagtagc aagttttctt
    24301 gccattatca cttttttaat cgtactcaat gtgcaacggt ctatgctctt acctggaggg
    24361 attttgggca tgactgtctg gctaatctat ctcttgctca aggaaccgac caatgtcatt
    24421 gtagctacct tcattgcagc cattattggt tcttgtgtca gccagatttt aagtattctt
    24481 tataagacac ctgctgtggt ctttatcttg gccattttgg caccgctggt tccaggttat
    24541 ctctcctacc gaacaactgc cttttttgtg acaggggact ataataaagc actggcaagt
    24601 gcgaccttgg ttgtcatgtt ggctttggta atctctattg gaatggctag cggaacagtg
    24661 attctcagac tgtatcatta tataaaaaca catcgagtat cgtagacttt acagaaataa
    24721 aagaattttc tgaaaaatga gataaataaa ttaacaacgc tttctatatg tgcgagaata
    24781 ccgcacttat gaagaaattg cggctgattt tggtatccac gaaagcaact tactccgtcg
    24841 gagccaatgg gttgaagtaa ctcttgttca aaggtggtgt tacgatttca agaactcctc
    24901 tcagttctga agacacggta atgattgatg cgacggaagt aaaaatcaat cgccctaaaa
    24961 aaaacaatta gcgaatgatt ctggtaaaaa gaaatttcac gctatgaagg ctcaagcgat
    25021 tgtcacaagt caagggagaa ttgtttcttt ggatatcact gtgaactatt gtcatgatat
    25081 gaagttgttc aaaatgagtc gcagaaatat cggacaagct ggtaaaatct tggctgacag
    25141 tggttatcaa ggacccatga agatatatcc tcaagcacaa actccacgta aatccagcaa
    25201 actcaagccg ctaacagttg aagataaagc ctataaccat gcgctatcta aggagagaag
    25261 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg
    25321 aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctggcatta tcaatcatga
    25381 actaggattc tagttttgca ggaagtctac tactttcctt attgtctgta aatctactga
    25441 ccttgttgtt tatcccagtc atggtttcta gttcgagctc agagtttcaa agtggatggc
    25501 aagagcatca attgattgct gagaaggtta gtaaaacact tgataagaca tttgataagg
    25561 atgtcagaga aattccgacc agtcagtttt atcaaaaatt tgtagatgag atgggaagga
    25621 cttactcagg aaatttgatc ctccaggagc tgataactgt gaatggagct tataaagcta
    25681 cttatatcgg tgaactctct agcaactaat cattctttaa aatgatgacc aataagaggc
    25741 ttgatttggt gaatcaagtc ttttttctct cttttactgc catttgtgat aaaatagtat
    25801 agaacgattt tttacatgaa tgataaaaca gaggtaaata tgacaatcgg tattgataag
    25861 attggttttg cgaccagtca atatgtcttg aaattacaag acttagcaga agcgagggga
    25921 attgaccctg aaaaattaag taaaggactc ttactcaagg aattgagtat tgcgccccta
    25981 actgaggaca ttgtgacctt ggcggccagt gctagtgact ctattttaac tgagcaagaa
    26041 agacaagaag ttgacatggt cattgtggct accgagtcag gaattgacca gagtaaggct
    26101 gcggccgtct ttgtgcatgg cttgctgggc atccagccct ttgctcgtag tttcgagatt
    26161 aaagaagcct gttatggagc gactgctgcc cttcattatg ccaaattgca tgtggaaaat
    26221 tctccggagt ccaaggtctt ggtcattgcc agtgatattg ccaaatacgg tattgaaact
    26281 ccaggagaac caactcaagg tgctggaagt gtagctatgt tgattacaca aaatccacgc
    26341 atgatggcct ttaataatga caatgtagct cagacccgtg acatcatgga tttctggcga
    26401 ccaaattact cgacaactcc ttatgtaaat ggtgtttatt ctacccaaca atacttggat
    26461 agtttgaaaa cgacttggct tgaatatcaa aaacgctacc agcttactct ggatgatttt
    26521 gcggctgttt gtttccactt gccttatcct aaattagcgc taaaaggctt gaaaaaaatc
    26581 atggataaga gcctgcctca agagaaaaaa gacctcttac aaaagcattt tgaccagtct
    26641 attctctaca gtcaaaaggt ggggaatatc tacacaggtt cacttttcct tggacttttg
    26701 tctctcttgg aaaatacaga tagcttgaaa gctggggata aaatcgccct ttatagttac
    26761 ggaagtggag ctgtggctga gttcttcagt ggtgaattgg ttgaaggata tgaagcttat
    26821 ttggataaag accgcttgaa caagctcaac caacgaactg ccctatccgt tgcagactat
    26881 gaaaaggtct tttttgagga agtaaacttg gatgaaacaa actctgccca gtttgctggc
    26941 tatgaaaatc aagattttgc cttggttgaa attcttgacc accaacgccg ttatagcaag
    27001 gttgaaaaat aatgaagata agttggaatg gattttctaa aaaatcatac caagagcgcc
    27061 tcgagctgct aaaagctcag gcgctcctta gtcctgagag acaagctagt ctggagaagg
    27121 atgaacagat gagtgtgact gtggcagacc agctgagtga gaatgtggtg ggaacttttt
    27181 ctctgcctta ttcgctggtt ccggaggtac ttgtcaacgg tcaggaatac accgttccct
    27241 atgtgacaga agaaccctct gtggttgcgg cggccagcta tgccagcaaa atcatcaagc
    27301 gtgcaggtgg ttttactgca caagtccatc agcgccagat gattgggcag gtagcccttt
    27361 atcaaattgc taatcctaaa ctagcgcaag agaagattgc cagcaagaaa gcggagctct
    27421 tggagcttgc caatcaagcc tatccttcta tcgttaaacg tggaggtggg gcgcgtgatc
    27481 tgcatgtcga gcagataaaa ggtgaaccag actttctcgt tgtttatatt catgtcgata
    27541 cccaggaagc catgggtgcc aatatgctca acaccatgct ggaagccttg aaaccagtct
    27601 tagaagaact cagtcaggga cagagtctca tggcaatcct gtccaactac gcgaccgatt
    27661 ctctggtgac tgcaagctgt cgcatcgcct ttcgctactt gagccgccaa aaggatcaag
    27721 gacgagagat tgcggagaaa attgcgttgg ctagtcagtt tgcgcaggct gatccttacc
    27781 gagctgctac tcataataaa ggaattttta atggtattga tgcgattttg attgccactg
    27841 gtaatgactg gcgtgccatc gaagctgggg cccatgcctt tgccagtcga gatggacgct
    27901 atcaaggtct tagctgctgg acgctggacc ttgaaagaga agaattggtc ggtgagatga
    27961 ccctgcccat gcctgtagcg actaagggtg gctctatcgg cctcaaccca cgtgtagctc
    28021 tcagtcatga tctactagga aatccttctg ccagagaatt agcccagatt atcgtgtcca
    28081 tcggtcttgc ccaaaatttt gcagccctca aagccttggt aagtacgggc atccagcaag
    28141 gccatatgaa actacaggcc aaatccctag ctctcctagc tggggctagt gaatctgaag
    28201 ttgctcccct agtagagcgc ctcatctcag ataaaacctt taacctagag acagcccagc
    28261 gctatctcga aaatttaaga tcataaaaaa ctcagacgaa tcggtctgag ttttcttgtg
    28321 tttaaatact ttttcctggt aatagtgtaa ctggtaagaa gtaaccagtt gtggcgactt
    28381 ccttgccttc aatcttttgc aaaagaagat caatagtgag acaagcaatc tcttccaaag
    28441 gttgcttgat agtagccaat tgagggtagt aattttcgat aaagtaggtc ccatcatagc
    28501 cgatgacctt gagctctttt gggacagaaa tgcccaattc ttgagcgatt ttaatgacca
    28561 gaatagctgt caaatcatcc gaagcaaaaa tggcatctgg tttttcctgg gtcaagatat
    28621 tcttgatttc catctctttt ctgacgggag aaaagtcact ggaaacattg ataataggag
    28681 cttttgggag tacggatgca aaaccagcgt ggcgcagtcc ggttggcgaa ttggaattgt
    28741 cattccctgt aatcatgatg atagactggg cacctgtctt gaccaaggtt tgggcagcaa
    28801 gaaccccacc agcatagttg tcagaggaga cgacagggat gtctggcgat aggtttcggt
    28861 caaaggaaat aatcggcgct gtcacacgat tgtagtcttc gattcctagg ttgtgactac
    28921 cagaaatgat gccgtccacc tgattggctt ccaacatttc gatgtattcg cgttccttct
    28981 cagaatcatg ttcactgttg cagatgatgg tcttgtaacc atttttgaag agttggtgtt
    29041 ccaatttatc aatcaattct gcatagaaaa cattggaaat attggggaaa atcaagccga
    29101 ttaacttagc tgattttcct tgcagactac gagccaggtt gttgggttta tagcccaatt
    29161 ctcgcatggc ttcattgact ttttggatgg ttttctcaga tagataccct tttttattga
    29221 taacccgaga aacggtagta ggactgacgc ctgcaagttt ggcgacatca gttagttttg
    29281 cgaccataat ctaattcata gtaagttcca gttgggtttc cagatttgat caggatacca
    29341 ttttggtccg catgtgggaa gacacgacca gaaaatactt tttctccttt attgatgaaa
    29401 atttcaaaga cagagttatc gatgaagatt gtagcagtag tagcctgatt ctcgataggg
    29461 caagaacgag ttgtcccaaa ttcttgggca tactgttctc cagcctggct acgatccact
    29521 gtcacttgac tgtttacaag gtcaaagttg attgaaagtc ccttaccttc tttatcagca
    29581 agtaagacaa tctcgctctg gctattagct tccaagttga gttcaagttc gtaagtgttc
    29641 ttggtttggg aacggtttga gaaggcttct tcagaagcac gaaggtcctt aatagcagcg
    29701 actggatact ggtagagctt gtcgtctttg atagtgagtt ccttgaccaa agagaaggtt
    29761 ccttggtggt caaaacggtc agatgggtaa gaaacatctg gcaaaccaag ccagctcact
    29821 gctagaacac gcccatcagg agcgttgaag gcttgagttg cataggcttc gaaaccgtaa
    29881 tccatgtttt gaagttgaga cacatctacc attttggcat ttttagggtc aaaggaagcc
    29941 ccaatcttat acatatttgg aaagatatta tcgtagtcta gaactttctt atccaatcct
    30001 tgtggacagt agagaaggac aggctgttcc tctacaaaga ccagattagg acattccatc
    30061 atgtaggcag tacggtcgtt agcaaagtca aggtcgccaa ctgcttgcca gtttgtgtag
    30121 tcgttattga tagccttgta gagacggacg aagccttttt tctccaagtc ctgtccaccg
    30181 acgacagcat agtattgacc tttaaagtta aaaatttgtg gatcgcggaa gtggtcagta
    30241 gagtctgctg gctggtcaat caagatcttg tcaatctttg taatcttacc ctccttgtcc
    30301 atcaaagcac cgatctggta tgggtgacgg atccagtttt catcgcgaac atttcctgta
    30361 taaaatagga ataagttatc gccaaattgc atggcagaac cagagtaggc accgtggcta
    30421 tctaatggag tatctggtaa aactttgatt ccagtttctt taaagtgaac caaatcatca
    30481 ctttctagct gtacccaaga tttcaaaccg tgggctgcac caaaaggaaa attctggtaa
    30541 aagaggatcc acttgccatc aaagtaagaa aagccatttg ggtcgttgag aagtcctgtt
    30601 tttggctcaa catggtaatg agtatgccat ggagattgtg ccatattttc ctttatatgt
    30661 tgaatttctt cttgcgtcca atcttgataa agtctgtaac gacgctcagt tgtccattcc
    30721 attcattcct ccaaaaatct tatcactttt aatagtaact gttttcgata aaaaatgcaa
    30781 gccttttata ttaaaaaaga gaaaaaactg tcaaacgatt atcataaaat aaatacagga
    30841 aatcaatcaa atttttacga aaatgtgaaa gataatgaaa taaaagactt tttaaccaag
    30901 gtttcaaact tatttttcaa gaaattcctg atgaaacagt caaaaacaat caatctaaag
    30961 cttgcccact aagtagatag aatatttttt ctgcaaaacg cttgacatat ttttaaaaca
    31021 tgataaaata atagtcgtaa gggcgaataa aatcgctttc aaacaagaac aaaatgttat
    31081 ataaggagat ttttgcaaat gaacaatcag gaaattgcaa aaaaagtcat cgatgccttg
    31141 ggcggacgtg aaaatgtcaa tagtgttgcc cactgtgcga cacgtctacg tgtcatggtc
    31201 aaagatgaag agaaaatcaa taaagaagtg attgagaact tggaaaaagt tcaaggtgct
    31261 ttctttaact cagggcaata ccaaattatc tttggtacag gtacagttaa caaaatgtac
    31321 gatgaagttg ttgtacttgg attaccaaca tcatctaagg atgacatgaa agcagaagtt
    31381 gctaaacaag ggaactggtt ccaacgtgct atccgtactt ttggtgatgt tttcgttcca
    31441 atcatcccag ttatcgtagc gacaggtctc ttcatgggtg tgcgtggtct tttcaacgct
    31501 cttgaaatgc cacttccagg tgactttgca acttacacac aaatcttgac agatacagcc
    31561 ttcatcatct tgccaggttt ggttgtgtgg tcaaccttcc gtgtatttgg tggaaatcct
    31621 gccgttggta tcgttcttgg tatgatgctt gtctctggct cacttccaaa cgcttgggca
    31681 gttgctcaag gtggtgaagt aacagcgatg aacttctttg gtttcatccc tgttgttggt
    31741 ttgcaaggtt ccgttcttcc agccttcatc atcggggttg tcggagctaa atttgaaaaa
    31801 gctgtccgca aggttgttcc agatgtcatt gacctcttgg taacaccatt cgtgacactt
    31861 ttggtcatgt ctatccttgg actctttgtc attggaccag ttttccacgt tgttgaaaac
    31921 tacatcctta ttgctacaaa agcgattctt agcatgccat ttggtcttgg tggtttcttg
    31981 attggtgggg ttcaccaatt gatcgtcgtg tcaggtgtgc accacatctt caacttgctt
    32041 gaagtgcaat tacttgctgc tgaccatgct aacccattca acgctatcat cacagctgct
    32101 atgacagctc aaggtgctgc tactgttgcg gttggtgtta aaacaaaaaa tccaaaactg
    32161 aaaacacttg ctttcccggc tgctctttct gccttcctag gtattacaga gcctgctatc
    32221 ttcggggtga acttgcgctt ccgtaaacca ttcttccttt cattgattgc tggtgcaatc
    32281 ggtggtggat tggcttctat ccttggactt gctggtactg gtaatggtat caccatcatc
    32341 cctggtacaa tgctttatgt tggtaacgga caacttccac aataccttct tatggtagct
    32401 gtatcatttg cccttggttt tgctcttact tacatgtttg gttacgaaga tgaagtagac
    32461 gcaactgcag ctgcaaaaca agctgaagtg gctgaagaaa aagaagaagt tgcgccagca
    32521 gctcttcaaa atgaaacact tgtaactcct atcgtcggtg atgttgtcgc tcttgctgat
    32581 gtcaatgacc cagtcttctc aagtggagct atgggacaag gtatcgctgt gaaaccaagc
    32641 caaggcgtgg tctatgcacc agctgatgct gaagtttcaa ttgcctttcc aacagggcac
    32701 gcttttggtt tgaaaacaag aaatggtgct gaagttttga ttcatgttgg tattgacact
    32761 gtatctatga acggtgacgg ttttgaagca aaagttgctc aaggtgataa ggtgaaagtt
    32821 ggcgatgttc ttggaacatt tgactcaaat aaaatcgcta cagctggact tgatgataca
    32881 acaatggtta tcgttacaaa tacagctgac tacgcttcag tagctccagt cgcaacaggt
    32941 tcagttgcga agggggatgc tgtgatcgaa gtgaaaatct aatcaatcct ctctaatgtg
    33001 aaaacgaaca aatgacatgt ttgttcgttt ttattagata gtaagattta cagaggaaaa
    33061 tctaaaaaat agagacattt agactttcga agtatgctat aataaagaaa ataaaaacaa
    33121 gaggtttatc atgacaaaat tatatggaag cttggaagct ggcggtacaa agtttgtctg
    33181 tgctgtcggt gatgaaaact ttaacgttgt agaaaaaaca caatttccaa caacaactcc
    33241 aatcgaaaca atcgataaaa ccattgagtt cttctcaaaa ttcgataacc ttgctggtct
    33301 tgcagttggt tcatttgggc cgattgatat tgacaaaaac tcaaaaactt atggctttat
    33361 cacgacgact ccaaaaccaa actgggcaaa tgtggacttg cttggtgccc ttcgtcgcgc
    33421 cctaaacgtg ccaatgtact tcacaacaga cgtaaacagc tctgcttacg gtgaagtggt
    33481 tgcccgtaac aatgctggtg gtcgtatcga aaacttggtt tactacacaa tcggtacagg
    33541 tatcggtgca ggcgtcatcc aacgtggtga gtttatcggt ggtgtgggtc accctgaaat
    33601 gggtcattat tatgttgcta gacacccaat ggatattgaa aaagagttta agggtgtttg
    33661 tcctttccat aagggatgtc tggaaggcta tgcagctggt ccaagtttgg aagctcgtac
    33721 aggtgtacgt ggggaaacta ttgaactcaa caaccctgtt tgggatgttc aagcctacta
    33781 tatcgctcaa gctgcggtta atgcgacagt gactttccgc ccagacgtga ttgtctttgg
    33841 tggaggggtc atggctcaac aacatatgct ggaccgtgtc cgtgagaaat ttacatctct
    33901 tcttaatggt tacctaccag taccagatgt gcgtgactat atcgtgacgc cagcagtcgc
    33961 aggaaatggt tctgccacac ttgggaactt tgttcttgca aaagaagttt caaaataaag
    34021 cacaaaatcc gcttgggaaa ccaaacggat tttgtggttg aaaacaatat ttttgagcct
    34081 ttccttaagt gattacggac ggtagcgact ttcttcgaaa ttccatacct aaactttgag
    34141 acactaggct caaagtttcc gaacacctga aaccattaga tttcaggtgt ttctatcacg
    34201 gtggaaaggc taggtaagtc ctcgcttcac tatcgaaaaa tatgcatgat ttccatacca
    34261 aagtatattt agtatcaagc tatagttaat ctacgcttta aaaatccact tgggaaacca
    34321 aacggatttt ttacgtgtca aagcatttgc cagaaaaagt caataatata ggtcagaccg
    34381 taggtataaa ccacgagggt aaagggtttg gtcagaatga tgatggtcat gtagcgcttg
    34441 aaactcatct tggtcagggc agccagcata cagagaaagt cagctgggct aatgggccaa
    34501 atcatcataa aaataaagaa gcggtcaaaa cgattgccct tatctagcca gccgatgtac
    34561 ttgtcgtagg tgcgcttgct gacgacagac tggacaaagg cagctccgta taggcgcact
    34621 agataaaaga taatggcaca gccaatcacg atgccgatat agttgtagat agtcccgatg
    34681 atgtgcccgt agataaagac cccagccacc gaggtcaagg cccctggaat gatagggacg
    34741 acagtctgta aaatctgtaa aaagataaag agaggtggac cccagatgcc tgcctgctgg
    34801 ataaaggcag agagggtttc cttggattgt aaaatcccag cctgataagc ccaaatacag
    34861 aaaatcaaac tcccaacccc accgacaatc gatgagatat tgataactcg ctgcaaaagg
    34921 ggagaaacag ctttcatttg tttatcctgt gacatgtaaa ctcctcatag atagtatatt
    34981 tctactatac catattttgg aggagaaagg gggaatgagt cttttttgat aaggaataga
    35041 aagtaaatag cccttcgaga cttagaatag gtctgtcaac taaaggttat atgcattcta
    35101 ggtttcgaat aatcgcaatt ccataaattt aaaagcattc taagtttcga atagcttatc
    35161 tgagataatt ttgaggcatt cgcgctttcg aatagtcatt ttccctaaag tttagatgta
    35221 ttctgaagct agaaagacta aaatctaaaa gtagtaagag tctctctctg atggacgtaa
    35281 tttatggcta gtatgaatcc tttgaattgt tagttaattt taatattaat cagttctgaa
    35341 ataattacta aatatagtta gatggtgagt taattattgc taaatttcaa gttcaagtta
    35401 gtcatccaga agtcttctct gggggacttg tagttcaagc attttttagg atagttgtta
    35461 atccactttt cgataaatgc gacttccttt gtagttgttt tcttagttcc ctgaggtaac
    35521 catctatgaa tgagcctgtt gtgattttca ttagatccta tagtgatgtg cataatagat
    35581 atagcagatt gaaactagaa tagtatacat ctacttctaa aacattgtta gaaatcaatt
    35641 tgactgtcct gatcaatttg tcctgttctt atttcatttt actatataat ccttagaaaa
    35701 catatcggac aagcggttga attctgttcc gtccattagt agataaagga ttactccttc
    35761 ttgaaatgac agatgaactt gtttcttata aaaatgttgt ctgaaactat tagccttttt
    35821 ccagaagttt tagaggaaga aaactttacg aggaaaaagg agttactcaa ataacaattc
    35881 aggattaaaa atagacagtt gaggagcgga aggtataaat taagtttgct actgtataat
    35941 ggatttatca ctaatactct tcgaaaatct cttcaaacca cgtcagcttc gccttgctgt
    36001 agatatagtt actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga
    36061 cttcgtcagt tttatctgca acctcaaagc tgtactttga gcagcctacg gctagcttcc
    36121 tagtttgctc tttgcttttc attgagtata aaagtgctcc aggctatatt ttacacagca
    36181 atagtcttct aaaaatggac aaaaacattg taaaggctat caaaaaggag tataatgagt
    36241 gcaagaaatt tcggaggtga aagatgctag aagtaagaag tctagagaaa agttttggct
    36301 ccaagcaagt tttgtttggt attgactttc aagcgcgacc aggtcgtatt ttgggactag
    36361 tcggaaaaaa tggtgctgga aaaacaacga ttttccatag tattttgaaa ttcctagaat
    36421 atcagggaga aatcggtctg gatggtcagg atattcgtca ggagacctat gctcggattg
    36481 gttatctgcc tgaagaacgc agtctcatgc ctaaattgac agttcttgaa caagttcgct
    36541 acttggcgac tctaaaaggc atggatgcca aagaagtcaa agaaaaactc cctcaatgga
    36601 tgaagaggtt ggaagtgaaa ggaaagctga cagataaaat caagagtctg tcaaaaggaa
    36661 atcagcagaa gattcagctc attattactc tgattcatga accagacctg attatcttgg
    36721 atgagccttt tagtggattg gacccagtta atacagaatt gctcaaacaa gtcatttttc
    36781 aggaaaaaga gcgcggagca accattatct tttctgacca tgtcatgacc aatgttgagg
    36841 aactttgtga cgatattctg atgattcgag atggccgtgt ggtcttgcac ggaccagttc
    36901 aggatgtccg caatcaatac gggaaaacgc gtctctttgt ttcaagtgaa cgaagcaagg
    36961 aagaattgga aaatcttcct catgtcaaac aggtgagctt gaccaaacaa ggcagttgga
    37021 aattgatttt ggaggatgag agcgctggaa gggaactctt cccaatcttg actcaaggtc
    37081 aatatatcgc aacatttgac caacaagcgc caactatcga tgaaatcttt aaactagaat
    37141 caggagtgga agtatgagaa atatgtgggt tgtaatcaag gaaacctatc ttcgacatgt
    37201 cgagtcatgg agtttcttct ttatggtgat ttcgccgttc ctctttttag gaatctctgt
    37261 aggaattggg catctccaag gttcttctat ggctaaaaat aataaagtgg cagtagtgac
    37321 aacagtgcca tctgtagcag aaggactgaa gaatgtaaat ggtgttaact tcgactataa
    37381 agacgaagca agtgccaaag aagcaattaa agaagaaaaa ttaaaaggtt atttgaccat
    37441 tgatcaagaa gatagtgttc taaaggcagt ttatcatggc gaaacatcgc ttgaaaatgg
    37501 aattaaattt gaggttacag gtacactcaa tgaactgcaa aatcagctta atcgttcaac
    37561 tgcttccttg tctcaagagc aggaaaaacg cttagcgcag acaattcaat tcacagaaaa
    37621 gattgatgaa gccaaggaaa ataaaaagtt tattcaaaca attgcagcag gtgccttagg
    37681 attccttctt tatatgattc tgattaccta tgcgggtgta acagctcagg aagttgccag
    37741 tgaaaaaggc accaaaatta tggaagtcgt cttttctagc ataagggcaa gtcactattt
    37801 ctatgcgcgg atgatggctc tgtttctagt gattttaacg catattggga tctatgttgt
    37861 aggtggtctg gctgccgttt tgctctttaa agatttgcca ttcttggctc agtctggtat
    37921 tttggatcac ttgggagatg ctatctcact gaataccttg ctctttattt tgatcagtct
    37981 tttcatgtac gtagtcttgg cagccttcct aggatctatg gtttctcgtc ctgaagactc
    38041 agggaaagcc ttgtcgcctt tgatgatttt gattatgggt ggtttttttg gagtgacagc
    38101 tctaggtgca gctggtgaca atctcctctt gaagattggt tcttatattc cctttatttc
    38161 gaccttcttt atgccgtttc gaacgattaa tggctatgcg gagggagcgg aagcatggat
    38221 ttcacttgct attacagtga tttttgcggt ggtagcaaca ggatttatcg gacgcatgta
    38281 tgctagtctc gttcttcaaa cggatgattt agggatttgg aaaaccttta aacgtgcctt
    38341 atcttataaa tagaagagcc ttgcgaaagc gaggttttta aaggtgaaaa gggtggaatc
    38401 acgaacctaa ttatgtacac attatgtaaa caggttgctt gaaaactcaa ttgtatagtg
    38461 aactgaatct ggaataggat aatattactt ctaaaacatt cttataaatt gatttgaatt
    38521 ccaaaatccc atcgttccgt tcttatttca ttttgcgata tagtgaaagg aaataagtca
    38581 gctcacaaaa aacgcataat atcaaggatt tttaacactt gatactatgc gttttctaat
    38641 tgtaaagact ttttgcctgg tctcttttgt tctatgagta tgttacatat ctaggtaaaa
    38701 attatttaaa gcaaattaac cttatttctc aagatgtagt aggttccgag ataaaagata
    38761 gctatgaata tgagttcttc aacaatggct atacctgctc ccatatagaa atggtcattg
    38821 agtcctacca gtgaattgac atagaaatta gaactaagat tgaagaaaag ttcaataaat
    38881 ccaatgacga tttggatacc aatgtagact gcaacagcga gtgctgtacg gtattcattg
    38941 aaaagctgtc caatggaaat agccaggtag atgcagagga ttcctgaaat agtatttagt
    39001 aggaaggata tacctgtaag aaagatctga gggagatgtg tttctacaaa tgtaatcaca
    39061 taagaaagag gaatccattc tggagctgtt aaagccagaa taataacagc acttagagcc
    39121 aatacagcgg tgctaatcaa tgaccagata aaggcaccga ttagtttggc tgtgatgata
    39181 tggtgttcag aaactggcaa ggtcaaagtc agatagcctt gtcggtcgta gacactacct
    39241 ttgaagcgtt taataatcaa gaaaatggtt gaaatcccaa gtgtaagcat caagccacca
    39301 aagactgtag ctagaaaaag tagcatagta gcctgacttt cttggtaagg tagattttta
    39361 aagccttgtg tctgtattcc gatgagggca gaaaggacta gcacggctgc gtagagggct
    39421 aaataccact tgttaacatt tttaaattcg tagcgaacta aattccaaaa cataaataat
    39481 ctcctttgct taggccttaa attcctgacg gaagagttgg tcaatggatt cacctgactc
    39541 gtagcgaata tcatctacat ttccttgacg gacgactttt ccgtctttta ggaagacaat
    39601 ttcatccaag attggctcga tatcagaaat caagtgggta gaaatcaaaa cggtagaagt
    39661 tggtgagtag ttgttgataa tggtattgag gatataagca cgggctgctg gatccacccc
    39721 accaatgggt tcgtccaaaa catagagacg agcatcacgg ctcataacca aaatcagttg
    39781 aaccttttct ttgtttcctt ttgatagttt cttgagacga ctattttcat caatgcccag
    39841 gtctgcaagt agatgatggg cgcgttcaag attgaaatct ttatagaagg tcttgaagta
    39901 ggttagggct tctttgacct tcatttgctc attgagatag gtcgtatcag gcaaataagc
    39961 tacaacggcc ttggttgctg ggcttgggtc catgtcgttg atgaggacac gtccttgatc
    40021 tggttgtaag aggccattaa ttagtttaat cagggttgtt tttcctgagc cgtttggccc
    40081 aagaaggccg acaatttttc cagctggaat gtcaagagaa acattttcaa gggctggtgc
    40141 tgctccatat gatttggata cattttcaaa tactagtaat gacataggct taaactcctt
    40201 taatataatc actgactacg cctggtagtt cttctttttc atagccaaaa tgggtcatgg
    40261 aggaaacgaa gtgttccaat tcttcttctg ataattgttt gcgtgactgg gcgattagct
    40321 ccttatcctt agtcacaaat cgtccagttg ttcgcttgct gtagacaaat ccttctcgtt
    40381 caaggtctga taaggctctt tggatggtat tgggattgac accagcctcg ctagctagct
    40441 ccctcacggt tggaagttgt tgattgggtt ccagtgtatg ggaaacaatc tgaagcttga
    40501 ttttctccat aatctgtaaa tagatgggtt ttttgttgtc aaatgtccag gacatcttag
    40561 tctcctttct cttatccttt tgtcttaatt aaataataca acaaaacaaa aaacttgtca
    40621 agcaaaaaga agaattgttt tgggaatcgc ttaaaaaatg gtataatgaa aagaaaacga
    40681 taaggaggga aaggatgcgt tgtccaaaat gtggggctac caagtcaagt gttatcgata
    40741 gtcgccaagc agaagaaggg aacaccattc gtagaagacg tgagtgcgac gaatgccaac
    40801 accgttttac aacctacgaa cgagtagaag aaagaacctt agtggttgtt aaaaaagatg
    40861 gtacacggga acaattctcc agagataaaa tctttaatgg gattatccgc tcagcccaga
    40921 aacgtcctgt gtcaagtgat gaaatcaaca tggtagtcaa tcgtatcgaa cagaaactcc
    40981 gtggtcgaaa tgaaaatgaa attcaaagtg aggacattgg ttcactcgtc atggaggagt
    41041 tggctgaatt ggacgagatt acctatgtac gttttgctag tgtctatcgt agttttaagg
    41101 atgtcagtga gttagagagc ttgctccaac aaatcaccca gtcctctaaa aagaaaaagg
    41161 aaagataaat gaagccaatt gaccgttttt cttatctaaa gaataatcgg gtgtcgcaag
    41221 atacctcatc tctggtacag tgctacctcc cgattatcgg tcaggaggca ctgagccttt
    41281 atctttatac aatcagtttt tgggataatg gtagaaagga atatcttttt tcaagtatcc
    41341 tcaatcatct caactttggg atggatagac tgataaaatc attgaaaatc ttatctgctt
    41401 ttaatctctt gaccctctat caaaaggggg atgtttatca gctagccctc catgctcctc
    41461 tatctagtca agacttcttg gagcatcctg tttatcgcag actcttagag aaaaagattg
    41521 gcgactctgc tgtggaggat ttgaaagttg aaagtgctga tggtgaagaa atacctgtct
    41581 cactcaatca agtctttcca gaattggcag aactaggcag tcaagaagac cttggtctca
    41641 agaagaaagt ggccaatgat tttgacttgg aacattttcg ccagctgatg gctcgagatg
    41701 gacttcgttt tgcggatgag cagtccgatg tcttaaacct ctttgctatt gccgaggaga
    41761 agaaatggac ttggtttgaa acctatcaat tggccaagtc aacagctgtt tctcaggtta
    41821 tttcaaccaa acgcatgcgt gaaaaaattg ctcaaaaacc agtttcctct gactttagtc
    41881 ttaaggaaac aaccattatc aaagaagcca aaagtaaaac tgccctgcag ttcttggcag
    41941 aaatcaagca aacacgcaag ggaaccatta cccaaacaga aagagaactc ttgcaacaga
    42001 tggctggctt gggcttgctg gacgaagtca tcaatatcat tcttttattg acctttaata
    42061 aggtcgattc ggcaaatatc aatgagaaat atgccatgaa ggtagccaat gactatgcct
    42121 atcaaaagat tcattcggca gaaaaggcag tcttgcgcat ccgtgagcga ggacagaaag
    42181 caaaaacaca aaaacagaat cagactgccc cagtaaaaac caatgttcct aaatggagta
    42241 atcctgaata taagaatgaa accagcgagg aaactcgtct ggaactagaa cgtaagaagc
    42301 aagaactatt agctcgatta gaaaaaggag gagattagat ggaaagtgtc ggagacgtac
    42361 tcaaacgtca acccagccgt ttttattatc aagatttggt ccagaaaatc atgaaggacc
    42421 ctgatgttgc ggcttttatc cagcaagaat ccttgactcc agaggaatta aatcgcagta
    42481 tctccaagtt taatcagtac atcaccgagc gtgacaagtt tctccgtggg gatacggatt
    42541 atattgccaa aggctacaag ccgattttgg ttaagaatca tggctatgca gatgtttcat
    42601 atgaagaaac tcctgagcta atcgcggctg aaaaagaagc ggctattaag aaccgtctca
    42661 agttaatcaa tctaccagcc agtctcaaga aagctagttt ggctcaagtt gacttggatg
    42721 atttggggcg cttaccagtt tttgaaaagc tactagcctt cgtggagcaa tatccagcta
    42781 ttcgaaaagg tctttactta tatggagact ttggtgtggg taaaagtttc atggtggcgg
    42841 ccttagctca tgatttatca gaaaaacgtg gtgtttcatc aactctcctc cactatccta
    42901 gctttgtcat tgatgtcaaa aatgctatca gtgatggcaa tgttaagacc ttggtggatg
    42961 agattaagct gtctgaggtc ctgattttag atgatattgg cgccgagcaa tccaccgctt
    43021 gggtgcgtga tgaaatcctg caggtcattc tccaatatcg gatgcaggaa aatttaccga
    43081 cctttttcac atccaacttc aactttgaag atttggagaa gcattttgcg aaagtgaaac
    43141 atggaaatga cgaaacctgg gaagccagac gggtcatgga acgcatccgt tatttggctg
    43201 aggagactcg tttagaagga gtaaaccgtc gatgacagaa accattaaat tgatgaaggc
    43261 tcatacttca gtgcgcaggt ttaaagagca agaaattccc caagtagact taaatgagat
    43321 tttgacagca gcccagatgg catcatcttg gaagaatttc caatcctact ctgtgattgt
    43381 ggtacgaagt caagagaaga aagatgcctt gtatgaattg gtacctcaag aagccattcg
    43441 ccagtctgct gttttccttc tctttgtcgg agatttgaac cgagcagaaa agggagccag
    43501 acttcatacc gacaccttcc aaccccaagg tgtggaaggt ctcttgatta gttcggtcga
    43561 tgcagctctt gctggacaaa acgccttgtt ggcagctgaa agcttgggct atggtggtgt
    43621 gattatcggt ttggttcgat acaagtctga agaagtggca gagctcttta acctacctga
    43681 ctacacctat tctgtctttg ggatggcact gggtgtgcca aatcaacatc atgatatgaa
    43741 accgagactg ccactagaga atgttgtctt tgaggaagaa taccaagaac agtcaactga
    43801 ggcaatccaa gcttatgacc gtgttcaggc tgactatgct ggggcgcgtg cgaccacaag
    43861 ctggagtcag cgcctagcag aacagtttgg tcaagctgaa ccaagctcaa ctagaaaaaa
    43921 tcttgaacag aagaaattat tgtagaaagt gagaaattat ggccctacca actattgcca
    43981 ttgtaggacg tcccaatgtt gggaaatcaa ccctatttaa tcggatcgct ggtgagcgaa
    44041 tctccattgt agaagatgtc gaaggagtga cacgtgaccg tatttatgca acgggtgagt
    44101 ggctcaatcg ttcttttagc atgattgata caggaggaat tgatgatgtc gatgctcctt
    44161 tcatggaaca aatcaagcac caggcagaaa ttgccatgga agaagcagat gttatcgttt
    44221 ttgtcgtgtc tggtaaggaa ggaattactg atgcagacga atacgtagct cgtaagcttt
    44281 ataagaccca caaaccagtt atcctcgcag tcaacaaggt ggacaaccct gagatgagaa
    44341 atgatatcta tgatttctat gctctcggtt tgggtgaacc actgcctatc tcatctgtcc
    44401 atggtatcgg tacaggggat gtactagatg cgattgtgga aaaccttcca aatgaatatg
    44461 aagaagaaaa tccagatgtc attaagttta gcttgattgg tcgtcctaac gttggaaaat
    44521 caagcttgat taatgctatc ttgggagaag accgtgtcat tgccagtcct gttgctggaa
    44581 caactcgtga cgctattgat acccacttta cagatacaga tggtcaagag tttaccatga
    44641 ttgatacggc tggtatgcgt aagtctggta aggtttatga aaatactgag aagtactctg
    44701 tcatgcgtgc catgcgtgct attgaccgtt cagatgtggt cttaatggtc atcaatgcgg
    44761 aagaggggat tcgtgaatac gacaagcgta tcgctggatt tgctcatgaa gctggtaaag
    44821 ggatgattat cgtggtcaac aagtgggata cgcttgaaaa agataaccac actatgaaaa
    44881 actgggaaga agatatccgt gagcagttcc aatacctgcc ttacgcaccg attatctttg
    44941 tatcagcttt aaccaagcaa cgtctccaca aacttcctga gatgattaag caaatcagcg
    45001 aaagtcaaaa tacacgtatt ccatcagctg tcttgaacga tgtcatcatg gatgccattg
    45061 ccatcaaccc aacaccgaca gacaaaggaa aacgtctcaa gattttctat gcgacccaag
    45121 tggcaaccaa accaccaacc tttgtcatct ttgtcaatga agaagaactc atgcactttt
    45181 cttacctgcg tttcttggaa aatcaaatcc gcaaggcctt tgtttttgag ggaacaccga
    45241 ttcatctcat cgcaagaaaa cgcaaataaa aaagtagaat ctggaatgac agttccggat
    45301 ttttttgata taataaaata atagaaaacg ctatcaaaag aagggggatg tcggtgatgg
    45361 aacatttgtt taaattctta cttttagcac cgtactttta ttttgataac tggattgaaa
    45421 aggccaacag aaatagtaag ttttttccaa ttttttatta tttttactgg ttttacatcc
    45481 ccttctattc tctttttagc cttgcttgga cagttgtttc agttctgttt ttcaataccg
    45541 tcttgagaaa tgtgacagat atcaagttat ggggcatttg gtttcttttt attctgctag
    45601 ctattggtat gaattggtta acttattcct gtttcaaaga aatgtttcgc ttgagacagg
    45661 aactagggaa gtctaagggt ggaaggcatt gatttatatc ggtttctatt tgtaggaggt
    45721 ggcttatggt acctctaaaa tcatttatta cacgctattc caaggtttat attggtaata
    45781 acatttaata gaacgaaact aaagaaaaca atttaaaaaa ggaggcttgt gatggaacac
    45841 ttgtttaaaa tgataatctt attaccctgt ttttactttt tcagctggat tgacaaggat
    45901 aatagagaaa gtaaattttt cccaattttt tactattttt actggattta catcaccctc
    45961 tatgctcttt ttagccttgc ttggacagtt ttttcagttc tgtttttcaa tatcgtcttg
    46021 agaaatttga cagatatcaa gttatggggt atttggctat tattactact tatcgctttt
    46081 gctagtgatt ggttagccta tgtctttttc aaaaaaatga ttcgcttgag gcgggaacta
    46141 gggaaatcta aaggtgtgca taaaggaagg tgtaggaact aaaaaatgac tgtatctatg
    46201 atttgtttat ggagctatag atacagtcat ttttattttg attatgaaac ttgagagaaa
    46261 tattcatctt gtatagtgga ttgaatatgg aataatacaa tacaacttat aaaacattgg
    46321 tataaaatgc tttagatccc ctaattgatt cgttcacatt ctattacatt ctattacaat
    46381 ctactataat aaaatgatga gagttattac aaattatagg tttgaaaaat cattaatttc
    46441 tttttcgagt attttaacta atgcctcttc tttggttagt cgtaataaag ttattccttt
    46501 atcaatcaaa tcggagttat gttgtagtat tcccaagcgt acttgagaga atccaagaat
    46561 atcgtatatt tttaattctt ctgctaatac caaaagttgt agggtgattg tttcacattc
    46621 tttgaataaa tgatgttgaa aatatacagt ggagagattg gctaaaaaag atgataaaaa
    46681 tgcttttgtt tctcggaagt atttatattt ctcgatggtt ttcataattc tatcaataag
    46741 aaggggaaga ttttcagaag gaaagaaaaa gagaatggtt ccaagcaatt tcaaatcact
    46801 aatgtaccat gtatccatag gttcaagata gtcccaaatt tcttcataca aatctttcaa
    46861 gacgtggttg tttttgaatc ctttagttcg taactctgtg acaatttttg tatgacgata
    46921 gatattttga ataggaacat cgtgatgtgt cttaagatat ttttgacatt tctcagtgag
    46981 ttcaaccatt tttctagtat cttgaaaagt agacggattt tggctctcta caataatatc
    47041 tcgcctttta ctaggatggt attcgttgca tatatacttg aattctgcca agctcatatc
    47101 aatttgttca agaagaaata ccatgttttc aaaactggga ataactttac cgtgttcaat
    47161 atttgttaga gttgttcgat gtatgacttg tccacataca tcttgttggg tcaatccttt
    47221 tgactttcga atttctttaa aaatttgtcc ataatcccat ctcatattgt tcctcctagg
    47281 taaatgtgaa tattttctac atttataaaa aacgtagaaa aaggtggtat tattatatca
    47341 aaaaggaggg aaaaagtcat gggctttaaa aaatatttga agaatttacc gaaaaactct
    47401 ggatttttga tttggagttg gattcaactt atctggtttg aaacatggtt ttggggataa
    47461 agaaattaga gtctatatat aataagtaaa ggaggaattt gtatgatata ccatcgttta
    47521 gaataagtct atatttaaaa tagaagttat aaggaatctt cttgaataaa aaatgaaagg
    47581 aaacagaaaa aatgaaaatt aagaaattat tgaaaatggt tattcctgtt ttaatgataa
    47641 gtgctgttgg aactactttc gtagaagcaa atcagatagg tgcttttagt aattttgtta
    47701 ttactaccag ttataagaga acaggttatt tgactaaaga aaatgaaggt gcggaatata
    47761 tcatgaactt aaatccttgt agaaatttac atcccatgac tgttaagcat cgtatagtaa
    47821 attctaatgg agaagctcgt agtggagaat cgttaacaac ctgtggtact cgttcaactc
    47881 atggtaattg ggcaacggtt ggctatgttt atgcagcaga tatggcaaga caaaattggt
    47941 gggatttatc agctgccatt tcaggtagtt ggtcaccaaa ttaattcgta aagtaggtat
    48001 aatttatgaa gattcctctc ttaactttgg caaggcataa atttgtttat gtcttgctta
    48061 ctttgctttt tcttgctttg gtttatcgtg acgttttgat gacttatttc ttttttgata
    48121 ttcatgcgcc cgatctagct aaattcgatg gacaagcaat taaaaatgac ttattaaaat
    48181 cagcattaga ttttcgtatt ctccagttca atctaggttt ttatcaatca tttattattc
    48241 caatcatcat tgttttgcta ggttttcaat atattgagct gaaaaataaa gttttacgat
    48301 tgagtattgg aagagaagtg agctatccag ggttaaaaag aaagttgact ttgcaagttg
    48361 caagtatccc ttgtttgata tatttagtga ctgtgctgac aattgcaatt ataacctatt
    48421 tccttgggac tttttctcct cttggatgga attctctatt ttctgatgga agtggtttac
    48481 aaagactcct agatggagag ataaaaagct atttgttctt tacttgtgtc ctgctaatcg
    48541 gtattttcat caatgcaatc tattttttac aaatagttga ttatgtgggg aatgtgactc
    48601 gttcggcaat cacctatttg atgtttcttt ggcttggttc tatgctgctc tatagtgcct
    48661 tgccttacta tatggttcct atgacgagtt tgatgcaagc tagctatggg gatgtaagtt
    48721 tgatgaaact ctttactcct tatatccttt atattgtccc ttacatggtg cttgaaaaat
    48781 atgaagataa tgtttaagaa ttttaacaat attttgctaa agagaaagat tgttttacta
    48841 cttcgtatag ttctgatgat gattttgata aaccatctat tgtcaacagc ggttcaaaag
    48901 caggatgctg ttatcttttt caagagagaa ttgatttcaa ttttttccta taatgactat
    48961 tctgaagcga atttagaaat ccccaaactc ttgttaaacc tttcgctttt catggtagga
    49021 tggctctctg tcattttact tgaaagtgat ttggcagacc attaccatca cttgattcgc
    49081 tatcaatcaa gctccttttt cgattataca aggaaacgat tggttgtcat ttctaaattt
    49141 tttactcaag atttgtttgt ctggttcctt ggtttacttc cgctaggaat tcatttcaaa
    49201 acagtcgcac ttttcttttt acttgctcag ttaatgatgt tgtacttact actgtcttat
    49261 ctgatagcac tgattagtgc gggcgctggt ttttcctttt ttctctattt tttagtattt
    49321 gtgggacaag aatggatgat ggatcatatt gtaacagtgt atttactact cttaagttta
    49381 ttagttatgt tgattgttag tcgcttggaa gagaaattta agaaaggata aacgatgaga
    49441 cttgaaatta taaatggaca gaaaatttat gggaaaagac ctattttaaa tcagttgaat
    49501 ttggtgtttc aatcaggaaa aatttatgga cttaaaggtg ataatggatc tggcaagacg
    49561 gttcttttaa aggtacttgc tggctatatt aagcttgaca aaggaaaagt tcttcaagac
    49621 gggaaagtct acgggataaa aaatcattat attcaggatg caggaatttt aattgaaaaa
    49681 gtcgagtttt tatctcattt atccctgaga gaaaatttgg aactgttaag gtatttttca
    49741 tctaaagtta cggaaaaaag aattgcctat tggattcaat actatgattt acaggaattt
    49801 gaagacgttg aataccgtca tttatccttg ggaacaaagc aaaaaatggc cttgattcaa
    49861 gcctttattt cctctccttc tatactcttt ctcgatgaac ctatgaatgc tttggatgag
    49921 aagagtgtga ggttaaccaa acaggtcatt ttatcttacc tgaaaaaaga aaatggtctg
    49981 gttatcctga cgtcgcacat atcggaagat atttcagacc tttgtacaga tgtattagtt
    50041 gtcgaaaatg gacatataca aatgtaaagg atatacaatc ctaggagatg gcttatggca
    50101 catctaaaat catttattac acgctattcc aaggtttata ttggtttagt tctgctgatc
    50161 tggctgtctt tcttctttat cccttgggat agagcgattc tgggggtaag gattgacatc
    50221 ttcatcatac agaaaatctt gctagctttt ggaattctgt ccattctcat ggccttgctg
    50281 tccaagaaag tcagtctctt tgtttttgga ctgatttgct gtctttctct ttggattaac
    50341 ttatttatca catttgccat tttgccgatt tttggcaatt aaacagtcat aaaagtcgga
    50401 gaggttagct tgaaaactaa cctctttttc cttttcaaaa tggggattct tccttgaaaa
    50461 taatcagtaa ttgtgctaaa attaaaggaa cattctaaaa tattcggaat ttaaagtaag
    50521 gaaaaacatg gctaatattt taaaaacaat tatcgaaaat gataaaggag aaatccgtcg
    50581 tctggaaaag atggctgaca aggttttcaa atacgaagac caaatggctg ctttgactga
    50641 cgaccaacta aaagcaaaaa cagttgaatt taaggaacgt tatcaaaatg gagaatcact
    50701 ggattcattg ctttacgaag catttgcggt tgtccgtgaa ggtgccaaac gtgtcctagg
    50761 tctcttccct tataaggttc aggtcatggg ggggattgtt cttcaccatg gtgacgtgcc
    50821 agagatgcgt acaggggaag ggaaaacctt aactgcgacc atgccggtat acctcaatgc
    50881 cctttcaggt aaaggggttc acgtagttac ggttaatgaa tacctgtcag aacgtgacgc
    50941 gactgagatg ggtgaattgt actcttggct tggtttgtca gtagggatta acttggctac
    51001 caaatctcca atggagaaaa aagaagccta tgagtgtgat attacttact caactaactc
    51061 agaaatcgga tttgactacc ttcgtgacaa catggtcgtt cgcgctgaaa acatggtaca
    51121 acgtccgctt aactatgcct tggtcgatga ggttgactct atcttgattg acgaggctcg
    51181 tacacctttg attgtatcag gtgccaatgc ggttgaaacc agtcagttgt atcacatggc
    51241 agaccactat gtaaaatctt tgaacaaaga tgactacatc atcgatgtgc agtctaagac
    51301 tattggtttg tctgattcag ggattgacag ggctgaaagc tacttcaaac ttgaaaacct
    51361 ctatgacatc gaaaacgtgg ctttgaccca ctttatcgat aacgcccttc gtgccaacta
    51421 catcatgctt ctcgatattg actatgtggt gagcgaagag caagaaatct tgattgtcga
    51481 ccaatttaca ggtcgtacca tggaaggtcg tcgttattct gatggattgc accaagctat
    51541 tgaagccaaa gaaggtgtgc caatccagga tgaaaccaag acatctgcct caatcacgta
    51601 ccaaaacctt ttccgtatgt acaaaaaatt gtctggtatg acgggtacag gtaagactga
    51661 ggaagaagaa tttcgtgaaa tctacaacat tcgtgttatt ccaatcccaa caaaccgtcc
    51721 tgttcaacgt attgaccact cagaccttct ttatgcaagt atcgaatcta agtttaaagc
    51781 ggttgtcgaa gacgttaagg ctcgttacca aaagggtcaa cctgtcttgg ttggtacagt
    51841 agcggttgaa actagtgact acatttctaa gaaattggtt gcagctggtg ttcctcacga
    51901 agtcttgaat gccaaaaacc actatagaga agcccaaatc atcatgaatg ctggtcaacg
    51961 tggtgccgtt accatcgcaa ccaacatggc gggtcgtggt accgacatca agcttggtga
    52021 aggtgttcgt gaacttggag gactttgtgt tattggtaca gaacgtcatg aaagtcgtcg
    52081 tatcgataac cagcttcgtg gacgttcagg tcgtcaagga gatccaggtg agtcacaatt
    52141 ctacctatct cttgaagatg atttgatgaa acgttttggt tctgaacgct tgaagggaat
    52201 ctttgaacgt ctcaacatgt ctgaagaggc cattgagtct cgcatgttga cgcgtcaggt
    52261 tgaagcagct cagaaacgtg tcgaaggaaa taactacgat acccgtaaac aagtccttca
    52321 atacgatgat gtcatgcgtg aacaacgtga gattatctat gctcaacgtt acgatgtcat
    52381 cactgcagat cgtgacttgg cacctgaaat tcagtctatg atcaaacgca cgattgaacg
    52441 tgtcgttgat ggtcatgcgc gtgccaaaca agatgaaaaa ctagaggcaa ttttgaactt
    52501 tgctaagtac aacttgcttc ctgaagattc tattacgatg gaagacttgt caggcttgtc
    52561 tgataaggcc atcaaggaag agcttttcca acgttccttg aaggtttacg atagtcaggt
    52621 ttcaaaacta cgcgatgaag aagcagttaa agaattccaa aaagttttga ttctacgagt
    52681 ggtggataac aagtggacag atcatatcga tgcccttgat caattgcgta acgcggttgg
    52741 acttcgtggc tatgctcaga acaaccctgt tgttgagtat caggcagaag gtttccgtat
    52801 gtttaatgat atgattggtt cgattgagtt tgatgtgaca cgcttgatga tgaaagcaca
    52861 aattcatgaa caagaaagac cacaggcaga acgtcatatc agtacaacag cgactcgcaa
    52921 tatcgctgct caccaagcaa gtatgccaga agatttggat ttgagccaga ttggacgcaa
    52981 tgaactttgc ccatgtggtt ctggtaagaa atttaaaaac tgtcacggta aaagacaata
    53041 aaatgagata gtttagaggc ggatatcttg tgaaaagtaa atttttactg ggtatccgtt
    53101 tgctttataa ggagatgagt tatggtattt acagcaaaaa gctctaaaat aaatatagaa
    53161 gaagttcgtg ccttgtcaaa attagaaggt caggctttgg agaggaaatc acagcgagat
    53221 caagagctag aagccattat acgtggagaa gaccagcgaa ttctcttggt aatcgggcca
    53281 tgctcatctg acaacgaaga agctgtcctt gaatacgcta agcgtttggc agtcctacaa
    53341 gaagaagtgg cagatcgtat ctttatggtt atgcgtgttt atactgccaa accccgtacc
    53401 aacggagatg gctataaggg cttgattcac cagcctaacg cgacagaagc gcctagtctt
    53461 atcaatggaa tcaaagccgt tcgccatctt cactatcgtg tcatcacaga aacagggatg
    53521 acaactgctg atgaaatgct ttatcctgaa aaccttccgc ttgtagatga tttgatttct
    53581 tacatggcag ttggtgcccg ttcagttgaa gaccagcaac accgctttgt ggcaagtggg
    53641 gcaggatttt ctactggttt taaaaatcca acctctggaa atctcaatgt catgtttaat
    53701 gggatttatg ctgctcaaaa caaacaaagt ttccttttct taggaaaaga agtagaaaca
    53761 actgggaacc cgctttcaca cgctattctt cgtggtgctc ttaatgagta tggaaaaaat
    53821 attcccaact actattatga caatttaatt gataccattg cccagtatga gaaaatgggc
    53881 ttggaaaatc cttttatcat cattgatacc aatcatgaca attctggtaa gcagtatatt
    53941 gaacagatcc gaattgtccg ccagaccttg attaaccgtg cttggaatga aaaaattaag
    54001 cagttcgttc gtggttttat gattgagtct tatctggaag atggtcgaca aaatgagcca
    54061 gaagtatttg gtaagtctat cacagaccct tgcctgggtt gggataacac agaagctctt
    54121 gtcagagaaa tttacaaaac gttaggagaa taagatggca tttattgaaa aaggtcaaga
    54181 aatcgatatg gaagtcatca aggctgaaac ccaattgtct gcagaagcct tgagactcaa
    54241 ggaaagccgt gacagggaat tggcagatat tatttcaggg gaagatgacc gtattctctt
    54301 ggtgattggt ccttgctctt ctgataatga agaggcggtc ttggaatatg ctcgccgttt
    54361 atccgccttg caaaagaagg tagcggacaa gattttcatg gtcatgcgcg tgtatactgc
    54421 taagcctcgt accaatggag acggctataa aggattggtt caccagccag atacttctaa
    54481 ggctccaagc ctgattaacg gcttgcaggc tgtgcgccag ttgcactacc gcgtgattac
    54541 agagactggt ttgacaacgg cagatgagat gctttatccg tcaaatctga tcttggtgga
    54601 tgacttggtc agctaccatg ccgttggagc tcgttctgtg gaagaccaag agcaccgctt
    54661 tgtggcttct gggattgatg caccagtagg gatgaaaaat ccaacctcag gaaatttggg
    54721 tgttatgttt aacgccatct atgctgctca aaacaagcaa accttccttt atcatgggca
    54781 ggaagttgag acatcaggta atcctttggc ccatgttatc ctccgtggag cagtcaacga
    54841 gtatggcaat tatatgccga attactacta tgaaaaccta ctccaagcca ttgaacgata
    54901 tgaaaccatg ggacttgaaa atccttttat cctcattgac accaaccatg ataactcagg
    54961 caagcaatat atggagcaga ttcgaattgt tcgccagacc ttgcagaatc gtgattggaa
    55021 tgagaaaatt aaaaagacgg ttcgaggatt tatgattgaa tcttacctag cagatggtcg
    55081 tcaaaaccaa ccagagatct ttggttgctc tattactgac ccttgcctag gttgggaaaa
    55141 tacagaggcc ttggtagaag agatttatgt taccttgaca aaataagtga aaaggatgga
    55201 gttggggaat ctcaactcct tttgatgaga atgatagttg gacacggaat tgacatcgaa
    55261 gaattggctt cgatagaaag cgcagttaca cgacatgaag gatttgctaa gcgtgtactg
    55321 accgctcagg aaatggagcg cttcaccagt ctcaaaggac gcaggcaaat agaatattta
    55381 gctggtcgct ggtcggctaa ggaggccttt tccaaggcta tgggaacggg cattagcaag
    55441 ctcggttttc aggatttgga agtcttgaac aatgaacgtg gggcgcctta ttttagtcag
    55501 gcaccatttt caggaaagat ttggctgtct atcagccaca ccgatcagtt tgtgacagcc
    55561 agtgtcattt tggaggaaaa tcatgaaagc tagtccacat agaccaacca aggctctgat
    55621 tcatctggga gctattcgac aaaatattca gcaaatgggg gctcatatcc ctcaaggaac
    55681 gctcaagttg gctgtggtca aggccaatgc ttatggtcat ggagctgttg ccgttgccaa
    55741 ggcaattcaa gatgatgttg atggcttttg cgtttccaat atcgatgaag ccattgaact
    55801 cagacaagct ggactcagca agccaatcct cattttagga gtttctgaaa tcgaagctgt
    55861 tgctctagct aaagaatatg acttcacctt gacagtggct ggactggagt ggattcaagc
    55921 actcttagat aaggaagtgg acctaactgg attgacagtc cacctcaaga ttgattcagg
    55981 gatgggacgg attggtttta gagaggcaag tgaggttgag caggctcaag atttgctcca
    56041 acaacacggt gtttgtgttg aaggaatctt tacccacttt gctactgctg atgaggaatc
    56101 agatgactat tttaatgccc agttagaacg gtttaaaact attttagcta gtatgaagga
    56161 agttccagag ctggttcatg ctagcaattc tgcaacgact ctttggcatg tagagactat
    56221 tttcaatgcg gttcgtatgg gagatgccat gtatggcctc aatccaagtg gagcggtctt
    56281 ggatttgcct tatgatttga taccggcctt gaccttggag tctgctctgg ttcatgtcaa
    56341 gacagttcca gctggagctt gcatgggcta tggagcaact tatcaagcgg atagcgagca
    56401 agtcatcgcg accgtgccaa tcgggtatgc agatggatgg acaagagaca tgcaaaattt
    56461 ctctgtcttg gtagatggcc aagcttgccc aattgtcggc agggtttcga tggaccaaat
    56521 cactattcga ttgcctaagc cttacccact cggaaccaag gtaaccttga ttggctccaa
    56581 tggggataag gaaatcactg caactcaggt agcgacctac cgcgtaacca ttaactatga
    56641 ggtggtttgc ctcctcagcg accgtattcc gagagaatat tattagaaaa gaaaggagtg
    56701 gagcatgaat ctacatcaac ccttgcatgt cttgcctggt gtgggaccaa agtcagcaga
    56761 aaaatatgcc aaactaggaa ttgaaaactt gcaagatctc ttgctctact ttcctttccg
    56821 ttatgaagac ttcaaaacca agcaggtgct ggagctggaa gacggtgaga aggcagttct
    56881 ttctggtcag gtagtgactc ctgctagtgt ccagtattat ggtttcaagc gcaatcgcct
    56941 gcgttttagt ctcaagcagg gagaggtcgt ttttgcggtg aatttcttta accagcccta
    57001 tctggctgat aaaatagagt tgggagcaac ccttgctgtc tttggaaaat gggaccgcgc
    57061 taaggctagt ctgactggga tgaaggttct ggctcaggta gaagatgacc tccagcctgt
    57121 ctatcgtctg gctcagggaa tcagtcaggc cagtctggtt aaggtcatca agacggcttt
    57181 tgatcaggga ctggacctct tgatagaaga aaatctgccc cagtctttac tagacaaata
    57241 caaactcatg tcccgttgtc aggcagtccg agctatgcat tttccaaagg atttggcaga
    57301 atacaagcag gctcttcgcc gtatcaagtt tgaggaactc ttttatttcc aaatgcagtt
    57361 gcagacgctc aagtctgaaa atagagttca gggaagtggt ctggttctga attggtctca
    57421 ggaaaaagtg acagcagtta aagtaagtct tccttttgcc ctgacccaag ctcaggaaaa
    57481 gagtttgcag gaaattttaa ctgatatgaa gtccgaccac cacatgaatc gtctcctaca
    57541 aggggatgtg gggagtggaa aaacggtagt cgctggcttg gccatgtttg cggcagtgac
    57601 agcaggttat caggctgccc taatggtacc aacagaaatc ctcgcagagc aacactttga
    57661 gagtttacag aacctttttc ccaatttgaa actggctctc ttgacaggtt ccttgaaagc
    57721 tgcagaaaag agagaagtct tggagaccat tgccaagggt gaggctgatt tgattatagg
    57781 aactcacgct ctgatacaag atggggtgga gtatgctcgt cttgctttga ttattatcga
    57841 tgagcagcac cgttttggtg tagggcaaag gcgtatttta cgggaaaaag gtgacaatcc
    57901 agatgtcctc atgatgacgg cgactcccat tccacggacg cttgccatca cagcctttgg
    57961 agatatggat gtttccatta tcgaccagat gccagcaggt cggaagccta ttgtgacgcg
    58021 ctggatcaaa catgagcaac tacctcaggt cttgacttgg ttagaggggg aaattcaaaa
    58081 aggttcccaa gcctatgtca tctctccttt gattgaagaa tcagaagctc tagatttgaa
    58141 aaatgccatt gccttatcag aggagttgac gactcatttt gcaggcaagg cagaggtggc
    58201 tcttctacat ggtaggatga agagtgacga aaaagaccag atcatgcagg atttcaagga
    58261 gagaaagacg gatattctgg tttcgacgac ggttattgag gttggggtca acgttcccaa
    58321 tgcgactgtc atgattatca tggatgccga tcgcttcggt ctcagtcaac ttcaccagct
    58381 tagaggtcgt gtcggtcggg gggacaagca gtcctacgct gttctcgttg ctaatcccaa
    58441 gacggattct gggaaagacc gcatgcgtat catgacagaa acgaccaatg gatttgtcct
    58501 tgcggaggaa gatttgaaaa tgcgtggttc tggtgagatt tttggaacca gacagtcagg
    58561 acttccagag ttccaagtgg ctgatattat cgaagatttt ccgattttag aagaagcaag
    58621 aaaggttgct agctacatta gttctataga agcttggcaa gaagatccag agtggcgcat
    58681 gattgccctt catctggaaa agaaagaaca tctggattaa gctttctcta aggaaaactt
    58741 aagctagttt ttaggtttgg ctcttatact aaagtcatca aaaagaaacg aggactctca
    58801 tatgacagta acgattaaag taaattacca aaccactttc caaaagaagg aagcaaaaaa
    58861 ctagtataaa cagaagagag agcgaaatgc tcttttttcg tttctaaaac tactttcagc
    58921 ccatcatcct aaaagtaaag aatctaaatt cactttctat ttacccttct ttcttgcatt
    58981 gattacatag atatgctaca gttgtggtaa cgattacaaa ataaaaggag catgctatga
    59041 aaaatccagc tttgctagaa gaaattaaga cctatagagg aagggatgag gttccggaag
    59101 actttgatgc tttctgggat ggggaagtga aaaatgtttc cacacttcca tcctaccact
    59161 tggaggaaag agatttccac attcctcaag tcaagtgcta tgagttaaca tttgaaggaa
    59221 gcaaggaagg aaaggtctat gcacgcattg ttcttccaaa gagtgaggag aaggttccat
    59281 taatcttcca ttttcatggt tatatgggac gtggctggga ctgggccgac atgctgggct
    59341 tcaccgtagc tggttacggt gttgtttcca tggatgtgcg gggccagtca ggttactcac
    59401 aagacggctt gcgttctcct ttaggaaata ccgtgaaggg gcatattatc cgtggtgcta
    59461 tggaaggtcg ggaccacctc ttttataagg atgtttatct ggatatttac cagttggtcg
    59521 aaattgttgc tagtctgtct caggttgatg agaagcgtct ttctagctat ggtgcctcac
    59581 aaggaggggc tctagctcta gttgcagcag cgctcaatcc tcgaattcag aaaacagttg
    59641 ccatttatcc cttcttgtca gacttcagac gggtgattga gattggtaat actagcgagg
    59701 cttacgacga acttttccgt tatttcaagt ttcacgaccc cttccatgaa acagaggagg
    59761 aaatcatggc gacccttgcc tatatcgatg tcaaaaatct tgcccatcgt atccaaggtg
    59821 aggttaagat gattacgggc ttggacgacg atgtttgcta tcccattacc cagtttgcga
    59881 tttataatcg tctgacctgc gataaaacct atcgcatcat gcctgagtat gctcacgaag
    59941 ccatgaatgt atttgtcaat gaccaagtct acaactggct ctgtggaagt gagattcctt
    60001 ttaaatatct aaaataagga gtcgactcta agcacaaaat cttaaaaatt acaaacacgc
    60061 atagtatcag gggattaaaa aaacttgata ctatgcgttt tatcatggaa atatagtaaa
    60121 atgaaacaag aataggacaa aacgatcagg acagtcaaat cgatttctaa caatgtttta
    60181 gaagcaaatg tgtactattc tagtttcaat ctattatatt tatagaattt tttgttgcta
    60241 gatttgtcaa attgcttaaa ataatttttt tcagaaagca aaagccgata cctatcgagt
    60301 agggtagttc ttgctatcgt caggcttgtc tgtaggtgtt aatacttttc aaaaatctct
    60361 ttaaaccacg tcagcttcgc cttgccgtat atatgtt
//
LOCUS       DAVEHY010000010        54443 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVEHY010000010 DAVEHY010000000
VERSION     DAVEHY010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54443
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.010"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            198..512
                     /locus_tag="VUZ44_000739"
     CDS             198..512
                     /locus_tag="VUZ44_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319693.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            522..728
                     /locus_tag="VUZ44_000740"
     CDS             522..728
                     /locus_tag="VUZ44_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319694.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            728..925
                     /locus_tag="VUZ44_000741"
     CDS             728..925
                     /locus_tag="VUZ44_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319695.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            928..1662
                     /locus_tag="VUZ44_000742"
     CDS             928..1662
                     /locus_tag="VUZ44_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU0319696.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1674..2315
                     /locus_tag="VUZ44_000743"
     CDS             1674..2315
                     /locus_tag="VUZ44_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0319697.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2333..2563
                     /locus_tag="VUZ44_000744"
     CDS             2333..2563
                     /locus_tag="VUZ44_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319698.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFLYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            2599..2679
                     /locus_tag="VUZ44_000745"
                     /pseudo
     CDS             2599..2679
                     /locus_tag="VUZ44_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2668..2853
                     /locus_tag="VUZ44_000746"
     CDS             2668..2853
                     /locus_tag="VUZ44_000746"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319699.1"
                     /translation="MDETDEVSSKHGFEVVDETDEVSSKHGFEVVDETDEVSSKHGFE
                     IVDETDEVSNRTTVRRR"
     gene            3004..4767
                     /gene="aspS"
                     /locus_tag="VUZ44_000747"
     CDS             3004..4767
                     /gene="aspS"
                     /locus_tag="VUZ44_000747"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU0319700.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            4745..5686
                     /locus_tag="VUZ44_000748"
     CDS             4745..5686
                     /locus_tag="VUZ44_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU0319701.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(5762..5842)
                     /locus_tag="VUZ44_000749"
                     /pseudo
     CDS             complement(5762..5842)
                     /locus_tag="VUZ44_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5978..6964)
                     /locus_tag="VUZ44_000750"
     CDS             complement(5978..6964)
                     /locus_tag="VUZ44_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU0319702.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(6974..7774)
                     /locus_tag="VUZ44_000751"
     CDS             complement(6974..7774)
                     /locus_tag="VUZ44_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU0319703.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(8027..8869)
                     /locus_tag="VUZ44_000752"
     CDS             complement(8027..8869)
                     /locus_tag="VUZ44_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU0319704.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(8871..10163)
                     /locus_tag="VUZ44_000753"
     CDS             complement(8871..10163)
                     /locus_tag="VUZ44_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU0319705.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(10274..11545)
                     /locus_tag="VUZ44_000754"
     CDS             complement(10274..11545)
                     /locus_tag="VUZ44_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU0319706.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            12095..13612
                     /gene="malQ"
                     /locus_tag="VUZ44_000755"
     CDS             12095..13612
                     /gene="malQ"
                     /locus_tag="VUZ44_000755"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU0319707.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            13638..15896
                     /locus_tag="VUZ44_000756"
     CDS             13638..15896
                     /locus_tag="VUZ44_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEU0319708.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(16941..17513)
                     /locus_tag="VUZ44_000757"
     CDS             complement(16941..17513)
                     /locus_tag="VUZ44_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319709.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(18136..18984)
                     /locus_tag="VUZ44_000758"
     CDS             complement(18136..18984)
                     /locus_tag="VUZ44_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU0319710.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            19136..19414
                     /locus_tag="VUZ44_000759"
     CDS             19136..19414
                     /locus_tag="VUZ44_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319711.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            19416..21479
                     /locus_tag="VUZ44_000760"
     CDS             19416..21479
                     /locus_tag="VUZ44_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU0319712.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYNKEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(21557..22813)
                     /locus_tag="VUZ44_000761"
     CDS             complement(21557..22813)
                     /locus_tag="VUZ44_000761"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU0319713.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAIRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            22955..25420
                     /locus_tag="VUZ44_000762"
     CDS             22955..25420
                     /locus_tag="VUZ44_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU0319714.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEEKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            25485..26396
                     /locus_tag="VUZ44_000763"
     CDS             25485..26396
                     /locus_tag="VUZ44_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU0319715.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGELSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIVLIILPMIFLSIEEAKESR"
     gene            26626..27324
                     /gene="dapD"
                     /locus_tag="VUZ44_000764"
     CDS             26626..27324
                     /gene="dapD"
                     /locus_tag="VUZ44_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU0319716.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            27392..28522
                     /locus_tag="VUZ44_000765"
     CDS             27392..28522
                     /locus_tag="VUZ44_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU0319717.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            28534..29073
                     /locus_tag="VUZ44_000766"
     CDS             28534..29073
                     /locus_tag="VUZ44_000766"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU0319718.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVAYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            29057..29734
                     /locus_tag="VUZ44_000767"
     CDS             29057..29734
                     /locus_tag="VUZ44_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU0319719.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(29801..30700)
                     /gene="galU"
                     /locus_tag="VUZ44_000768"
     CDS             complement(29801..30700)
                     /gene="galU"
                     /locus_tag="VUZ44_000768"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU0319720.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(30722..31738)
                     /locus_tag="VUZ44_000769"
     CDS             complement(30722..31738)
                     /locus_tag="VUZ44_000769"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU0319721.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            31950..32390
                     /locus_tag="VUZ44_000770"
     CDS             31950..32390
                     /locus_tag="VUZ44_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0319722.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(32513..32929)
                     /locus_tag="VUZ44_000771"
     CDS             complement(32513..32929)
                     /locus_tag="VUZ44_000771"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0319723.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(32997..33647)
                     /gene="phoU"
                     /locus_tag="VUZ44_000772"
     CDS             complement(32997..33647)
                     /gene="phoU"
                     /locus_tag="VUZ44_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU0319724.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(33662..34414)
                     /gene="pstB"
                     /locus_tag="VUZ44_000773"
     CDS             complement(33662..34414)
                     /gene="pstB"
                     /locus_tag="VUZ44_000773"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU0319725.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(34416..35231)
                     /gene="pstA"
                     /locus_tag="VUZ44_000774"
     CDS             complement(34416..35231)
                     /gene="pstA"
                     /locus_tag="VUZ44_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU0319726.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(35224..36087)
                     /gene="pstC"
                     /locus_tag="VUZ44_000775"
     CDS             complement(35224..36087)
                     /gene="pstC"
                     /locus_tag="VUZ44_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU0319727.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(36205..37080)
                     /locus_tag="VUZ44_000776"
     CDS             complement(36205..37080)
                     /locus_tag="VUZ44_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU0319728.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(37247..38578)
                     /locus_tag="VUZ44_000777"
     CDS             complement(37247..38578)
                     /locus_tag="VUZ44_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU0319729.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(38579..39286)
                     /locus_tag="VUZ44_000778"
     CDS             complement(38579..39286)
                     /locus_tag="VUZ44_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0319730.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(39370..39846)
                     /locus_tag="VUZ44_000779"
     CDS             complement(39370..39846)
                     /locus_tag="VUZ44_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU0319731.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            39853..40381
                     /locus_tag="VUZ44_000780"
                     /pseudo
     CDS             39853..40381
                     /locus_tag="VUZ44_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(40696..42387)
                     /locus_tag="VUZ44_000781"
     CDS             complement(40696..42387)
                     /locus_tag="VUZ44_000781"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU0319732.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            42523..42969
                     /gene="argR"
                     /locus_tag="VUZ44_000782"
     CDS             42523..42969
                     /gene="argR"
                     /locus_tag="VUZ44_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU0319733.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            43020..45554
                     /gene="mutS"
                     /locus_tag="VUZ44_000783"
     CDS             43020..45554
                     /gene="mutS"
                     /locus_tag="VUZ44_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU0319734.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            45701..47395
                     /gene="patA"
                     /locus_tag="VUZ44_000784"
     CDS             45701..47395
                     /gene="patA"
                     /locus_tag="VUZ44_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU0319735.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(47725..47988)
                     /locus_tag="VUZ44_000785"
                     /pseudo
     CDS             complement(47725..47988)
                     /locus_tag="VUZ44_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            48186..49952
                     /gene="patB"
                     /locus_tag="VUZ44_000786"
     CDS             48186..49952
                     /gene="patB"
                     /locus_tag="VUZ44_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU0319736.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            50091..50780
                     /locus_tag="VUZ44_000787"
     CDS             50091..50780
                     /locus_tag="VUZ44_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU0319737.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            50784..50963
                     /locus_tag="VUZ44_000788"
     CDS             50784..50963
                     /locus_tag="VUZ44_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319738.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            50950..52299
                     /locus_tag="VUZ44_000789"
     CDS             50950..52299
                     /locus_tag="VUZ44_000789"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU0319739.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            52423..53883
                     /locus_tag="VUZ44_000790"
     CDS             52423..53883
                     /locus_tag="VUZ44_000790"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU0319740.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            53897..54328
                     /locus_tag="VUZ44_000791"
     CDS             53897..54328
                     /locus_tag="VUZ44_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU0319741.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
BASE COUNT        16012 a        10279 c        11850 g        16302 t
ORIGIN      
        1 aaggtgaagc tgacgtggtt tgaagagatt ttagaagagt attaatgata gataaagtgg
       61 tcaggaacct actcctgacc tttttctttt gcaaaatgac aaaaatcata aactttttga
      121 caactataat tgtcaaaaag aaaaagatat gttacaatga attcaagtta agaaatagga
      181 agcagaaagg agttataatg tgggtactag gatttatact atttatgatt ttcttttatt
      241 ctaataattc taaaaaaatc aagaaactag agaataaaat caaaaaactt gagcgaaaag
      301 agaaaggaaa cgcagaaatg tcgagattat tgcaagaaat gattggaaag gaaccaatta
      361 taacgggagt gtatattggg ccagataact gggaagttgt ggatgttgat gaggaatggg
      421 taaagctacg acgtgtagat aatacgggaa aagaaaaatt caagttgcaa cgtattgaag
      481 atatccaaac cgttgaattt gacggagagt aggtgtgtaa cgtgcaacta aaaaatcgtc
      541 taaaagagct tcgagctcgc gatggtctca atcaaaccga cctagccaaa ctggcagggg
      601 tttccagaca gaccattagc ctactagaac gggatgagta caccccatcc attatcattg
      661 ccctgaaaat atctcaaatt ttcaacgaaa cagtcgaatc ggtatttcgt ttggaggagg
      721 acgagtgatg aacaagtata aagtgattta ttatgtagtg gtcatagctt tattagtcag
      781 cgtatttcta ctgattggga tggacctaag ctggtttaat ccctatcaaa gcgaccaatt
      841 tgtttgggtc tactttgctc tcatcccagt aattgaatgg attgaaaaga aatccaaaaa
      901 tctagcaagt gaaaaaggag aatgaatatg aaaaagaaac gtagattgtt atttttgatg
      961 tctattgtct tgggggggtt cttgggcatg tttgtaggga tgtttaaggc acgtgtcgaa
     1021 tcccacgaaa ttattttaga tgtaaaagcc ttgatgccat ggatatcagc tatttgttta
     1081 ctgataggtt tcattagtat gtttttgact ttcaatttct taaagaaaag cagaaaattt
     1141 cattccttgt atcaagagga aatggatgac gatctgaatg aaacctatta tgtgcaaatg
     1201 tatcggaatc ttgagtttgg aaccattgct tttaatatta caggtgtagc gattccattg
     1261 gctattttta tttcattaag tgaggtgatt atattgcata caaaccctca aacatttttc
     1321 ctttctttct tactctttgt ggtattctta gtcgctcaaa aatctctttt taaaaccatt
     1381 gcgattgttc gtcagtttga tttggaattt ttcgctacac caaaggatgt cttgaactat
     1441 ataaattctt atgatgaagg ggagcgtcag gctaatttgg aacagagttt tcgaatttta
     1501 ttccaattac accaatatgt cttaccagcc ttatatattt ttcttattat catttctttc
     1561 ttgacaggag agattcagtt actagctttc ttgcttgtag gagccatcca tgtttatatc
     1621 aatgtgatgc agttacctat ggtaaaacgt tatttcaaat aaaggagtta tctatgaaac
     1681 tacttaaaaa ccttggctgg tttcttctag cccttctatc ctttttcttt atctatggct
     1741 ttattcaggg gctcgcgact gcgtcgcttg ctttaggcgc ttcaccctat gctgttactc
     1801 tactctatgt ggtcttggct ggagtatatg tgtacggcat ttacaaatgg tatcagaaag
     1861 ctcctgttta tattgagaag agcggcttta accgatttat ttggcttcct gccttggttt
     1921 ggttcttatc tctggtcgtt caattcttct tgccagatga tccttcagta aatcaacaaa
     1981 tagcgacaga cttgaccttg tctcaaccac ttttctcatt ctttgctgtg gttatttttg
     2041 ctcctttgac ggaagagatt gtttttagag ggatgttagc acgctatctc tttcctaagc
     2101 aggacaatag taaacgaacc ctgatttttc ttctggtatc tagtcttcta tttgccttga
     2161 ttcattttcc aggtgatgtg caacaatttt ttgtctattt tagccttggt tttagtttgg
     2221 gtttggctta cattagcaga aaaggtctgg tctacagtat ttctcttcac gctttgaata
     2281 atttagtcgg ctttttgatg attctcatgc tataatagag tcaggaggtc acatgaaacg
     2341 agtaatttta gtagcagtga ttcaggcagt cgttctattt ttcatcattg gagcgctagc
     2401 ttatgccttc aaaggcgatt tcctctataa ctatctagca gttgtctttg ctcctattgc
     2461 aggtgtactg cgttttggga cggcttacat aacggaaatt gtcttgcctc gaaaggcagc
     2521 cgaaatcgct gaaaagcgta aagcaggcaa aaattcaaaa taaaagaatc cggtgaagtt
     2581 catcggattt ttgtattata ctcaatgaaa atcaaagagt aaactaggaa gctagccgca
     2641 ggttgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagttag ctcaaaacat
     2701 ggttttgagg ttgtagatga aactgacgaa gtcagctcaa aacatggttt tgaggttgtg
     2761 gatgaaactg acgaagtcag ctcaaaacat ggttttgaga ttgtagatga aactgacgaa
     2821 gtcagtaacc gtactacggt aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt
     2881 attagcgcta atttttaggg ctttcacttg acttttaaag actggcaaac ttttctgatg
     2941 attttcatga agagcctgcg cttttatggt aaaatagtaa cagaataaaa gaggagagaa
     3001 ataatgaaac gtagtatgta tgctggtcgt gttcgtgagg aacacatcgg acaagaaata
     3061 accttgaaag gatgggttgg ccgtcgtcgt gaccttggtg gtttgatctt tatcgatctt
     3121 cgtgaccgtg aaggaatcat gcagttggtt atcaaccctg aaaaagtatc tgcagaggtt
     3181 atggcaacag ctgaaagcct tcgtagcgaa tttgttattg aggtgactgg tcaggtcgct
     3241 gcgcgtgagc aagccaatga taagttgcca actggtgcgg ttgagttaaa cgtgacagct
     3301 cttattgtgc ttaacacagc taagacaaca ccatttgaga ttaaggatgg cattgaggca
     3361 aatgacgata cacgtttgcg ttaccgttac cttgaccttc gtcgtccaga aatgttggaa
     3421 aatcttaaac ttcgtgccaa ggtgacccac tctatccgca actacttgga tgagttggag
     3481 tttatcgacg tggagacacc attcctttct aagtcaacgc ctgaaggggc gcgtgattat
     3541 ttagtgccgt ctcgtgttaa taaggggcat ttttacgctc ttcctcaaag tccacaaatc
     3601 acgaaacagc tcttgatgaa tgctggtttt gaccgttact accaaatcgt taaatgtttc
     3661 cgtgacgagg acttgcgtgg agaccgccag cctgaattta ctcaggtcga cttggaaacg
     3721 tccttcctta ctgagcaaga aatccaagat attacagaag gcttgatcgc gcgcgtgatg
     3781 aaggaaacaa aaggcatcga agtaacgcta ccgttccctc gtatgaaata cgatgatgct
     3841 atggctcttt acggttctga caagccagat actcgttttg acatgttgct tcaggacttg
     3901 acagaagtgg tcaaaggtgt agactttaaa gtcttttcag aagcacttgc tgtaaaagcg
     3961 attgtggtca aaggagctgc ggacaactat tcacgtaaag acatcgacaa gatgacggaa
     4021 gtagccaaac agtatggtgc caaaggtctt gcttgggtca aggtggttga tggagaatta
     4081 aacggaccag ttgccaagtt cttgactggt atccaagaag aattgacaac agcgcttgct
     4141 cttgaagata aggacttggt tctctttgtg gcggatacgc ttgaagtggc taatgcaaca
     4201 ctgggtgccc ttcgtggacg tattgctaaa gagcttggct tgattgataa tgataagttc
     4261 aacttccttt gggtggttga ctggccgatg tttgaatggt ctgaagaaga aggccgctac
     4321 atgagcgccc accatccatt cacacttcca caggaagaga ctgctcacga attagaaggt
     4381 gatttggcta aggttcgtgc cattgcttac gatatcgtct tgaacggtta tgagcttggt
     4441 ggtggtagcc ttcgtatcaa ccaaaaagac cttcaagaac gcatgttcaa ggctcttggt
     4501 ttctcagctg aagaagccaa tgaccagttt ggtttccttc ttgaagccat ggactatggt
     4561 ttcccaccac acggtggttt ggctatcggg cttgaccgtt ttgtcatgtt gcttgctgga
     4621 gaagaaaata tccgtgaagt cattgccttt cctaagaaca acaaggcaac tgacccaatg
     4681 acacaagctc catcaacagt cgctctcaaa caactagagg aactcagctt acaagtagaa
     4741 gaagatgaaa caagcaaaac gaattaagcg gtggcgctat tatctgcgcc gctttgctta
     4801 tcagataaaa attttacgtg tcttacaaag tatctctcga gaaaagtatg atgagaagat
     4861 ttcggcctct ctggtctatg gttttttatc agcagtagca gttaatttct ttttccaacc
     4921 agggcatgtg tattcgagtg gtgcaacagg tctggcacag attatctctg ccttgagtaa
     4981 tcactggttt ggttttcata ttccgatttc gctaagcttc tacgccatta acttcccttt
     5041 gatggtctta gcttggtatc agattggcca taagttcacc gtctttacct ttatcacggt
     5101 atctatgagt tccttcttta tccagtttgt ccctgtggca accttgacgg aggatcccat
     5161 tatcaattcc ctttttgggg gtgttgttat gggtttgggg attggttttg ctcttcgaaa
     5221 caatatctcc agtggtggga cggatatcgt cagcctgact attcgcaaga aaacgggtaa
     5281 gaatgtcggt agtatttctt tcttggtaaa tggaactatc atgctgatag caggtttaac
     5341 ctttggttgg aaatacgctc tttattctat gattaccatc tttgtctcta gccgtgtgac
     5401 agacgcagtc tttactaagc aaaagcgtat gcaggccatg attgtgacaa atcatccaga
     5461 gaaggtaatt gaaaaaatcc ataaaaaatt gcaccgcgga gcaaccatga tccacgatgc
     5521 agaaggaacc tataatcacg agagaaaggc agttttaatc actgtcatta cacgtgcaga
     5581 gtttaatgaa tttaaacaga ttatgacaca agtggatcca agctcctttg tctctgtctc
     5641 ggaaaatgtt catattctag gaagatttgt tgagatagat aattagtgat taatactctt
     5701 cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta ggtatggtta ctgacttcgt
     5761 cagtttcatc tacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt
     5821 gcactttgat tttcattgag tataaaaaga tcttgggaaa agactcaatt tcagtagaaa
     5881 aggaagtaaa tcttcccaca ttaaaacgca tagtatcaag ttttttcaat acctgatagt
     5941 atgcgttttt gcttttaacg actttttgcc cagtctctta tttttcgata attttgtggg
     6001 cgatcaattg acggtaacaa atttgtttat tgtttttatt atcattaata atctggagaa
     6061 tagtttcaag ggaaacacga ccaagctcta aactattgat atcgacatag gctgccaagt
     6121 tgagcttggg attaaccgag tcaaagctga gaacagggac atccagctgg tgtttggcaa
     6181 tatagttaca aacaccttca gctaggaggc tatcggttgt gatgatagca tcaatttgtg
     6241 gatcgtgctt gaataatcgc ttgctaaatt tatagccctt ttcttccaga aactcgtcgg
     6301 caaagtagat gcgattgttg tcagtggtaa gtttgtaatg tttaagcgcc tgttcatagc
     6361 ctgttaaacg gtctttggtc acgaagagct ttttacttcc tccgataaag gcaatgcgtt
     6421 tgcagccttt tttgatgaaa tattcagtcg catcaaaacc agcttgaaca ttgccgttgt
     6481 cgacaagtgg gatgaaagga gatagagatt tacctaagat aaggaagggg aactgttctt
     6541 ctgcgacgag ttttacgaga gggtcttctt cttgggcata gagaaagatt agcccatcta
     6601 cacgcttgcc gtagaccatt tgtgaaatag cgttgagacg ctccttctca tctttccctg
     6661 ttgctatctg aatggcatag tggttttcag atgcgacttg agagatgcca cgtagaaccg
     6721 atggaaagaa aggattctgg tagaaggcgt ctgagtcatc aggaagaact aatccgataa
     6781 cctgagtata gctgcttacc aagctacgag cgttgaggtt tgggtggtag ttgagttcct
     6841 tcatagcttt gcgaacgcgt ttttttgttt cgtcgctaat ggttgattta ttttgaataa
     6901 cacgggttac ggttgaaggc gaaacaccag cagccttggc cacgtcttta atcgtaacgg
     6961 gcataaaaat ctcctattta tggtaatttg gatcacggaa atgtgtttta taaaagatag
     7021 tgaccagata cagaacaaaa agaatatttt gtacagtaat cagggttgtc atattttggc
     7081 caaataatcc caaaataagt gtaatcagag tcggcaatcc taaacagttc aagataaagt
     7141 gatagcactc tttaaaggtt ctaaatgaaa agaggcgtga tttcttagtg atataaagga
     7201 gaagactagc tcctagagag acgataaaga aattcaaacc aaagaggaag ctcgcaccga
     7261 gaactaggaa gaggctgata tagacacgat tttgttggta ccagtcttta gaaattgctt
     7321 gggtcaagct gtctttgctt ttgaaactct cagtctgaat ggctcggtaa gagatgcggg
     7381 tcagctcctt gctttccttg ctgatgacta gctcatttgt atcgaaatgc agttgcaagt
     7441 ccttaggtaa ttccttgatt tgacttggac caatcacaac agaaggggtt tgactagctg
     7501 ttccagtata agttaatgtg ccatcgacaa ttgtagcatg ttcagagaga tcctggacaa
     7561 cctcatttgt cagaggttca tagacattat cgataaaagt ttctagcgga taggtctcct
     7621 gggagctgtt ttggatagca atgggtacca tagacaagct gataaggaag atactggtaa
     7681 agagaagttg aaaccagttg agctcgaaac gtttggacag gggcttacga aacccccaaa
     7741 tacttgaaaa ataggaaaat ggatatggaa gcataggtat ctttctaaaa ggtgttttct
     7801 atatgagtat tattatatag agaaatgcgc tttatttcaa gtctaggaga aaaattgctt
     7861 gctacaagga tattatttac agtgacaatt gctaataatc aatgaaaatc aaagtgcaaa
     7921 ctagccacag gttgctcaaa gcacaacttt gaggttggag ataaagctga cgtggtttga
     7981 agagattttc gaagagtata aaatgaaaaa gggtggcggg gataaattat cccttgtcgc
     8041 caccacttgt aagtcctgaa acaaagttct tttgtaggaa aaagaagaga atacagattg
     8101 gaagggcgat gaggatagca cctgctgaga agtaggcaat cttcaagttt ttcgcattgt
     8161 taacgaaggt ttggagacct acggcaacag taaagtattc tttctcacga agcaagaaac
     8221 tagagaggat gtagtccccg aaaggtccca tgaaggccca gagagcttgt acggcaacca
     8281 ttgggcgaac aagtggtaga acaatttgcc agaagcggcg gaagtgtcct gcaccgtcta
     8341 gttttgcaga ttcgtctaaa gacattggca ctgtatcgaa gtagcctttc atgagccaag
     8401 cattcatcgg gataccacca ccaacgtaga ggaagatgag gaaccagttg tggttaaggg
     8461 cgttcaacat aagcgccata acgaagaagg ctgtcaaagc ggccatagtt ggcaccattt
     8521 ggatgatcaa gaagaagacc aaactttgtt tacgagccaa gaagttgtaa cggctgtagg
     8581 cataaccagc aagtacgatg atacttgttt gaacagccat ggtaattaag gcgataatca
     8641 aagtgttgag gtaccaagta ccgtacaagg tttcagtgaa gaggccttta aagttatcaa
     8701 aattgaggtc gatattagta tctagtttaa aggctgagac gttacctgct ttaaaggctg
     8761 acataatggt aatcaacagt ggatagataa ttacaattga tagaccaatc aggtaaaggt
     8821 aagtaaggct ttgagtcagt ctacgtttga gtttaattga gttattcatc ttagacgtcc
     8881 tccatatcaa atgcgtgtag tttcttgaat gcgatcatag agattgagat gacaatgata
     8941 gagataatca aggtaacagc tgccgccatt gagtattgag gagatgtacc tgttgtcaaa
     9001 cggtagatcc atgagatcaa gatatcggtt gaaccagctc cacctccgac actaccaggt
     9061 cctccaccat tgaagaggta catgatagag aagttgttaa agttgaaggt gtattggcta
     9121 atcaaagtag gtgccgcaac agccaaaatc attgggaaag tgatgttgcg gaatttttgc
     9181 caagcgttgg caccgtcaat ataagctgct tcgtaaaggt cgttaggaat agattgcaag
     9241 atacccaaag tcaaaacgta gatgtatggg aatccgagcc aaccttgcat cataatcaag
     9301 gcaatcttag tccaagttgg gtctgttttc caaggaataa gagctccatc aaggaaagga
     9361 aggaatttag ccaagattgg caatacttga gtgttgatag caccgacact atcgttaaac
     9421 atgtttgaga atgtcaagat agtgatgaag gctgggacag cccaaggaag aaggaaaata
     9481 acaccaaaga tacgttttcc tttgataaat ggttggttgg caatgatagc tgtgaagata
     9541 ccaattacga tttgtaaagt agaagctgcc aaagcccaaa tgatagtcca agaaagaaca
     9601 gaaccaaagg cagaacggaa ggtactcaag ctccaaatgt ttgtaaagtt ggtcaaacca
     9661 acccagtcca acaacttgtt tggtggcaag tgttggaagt cgtagttggt aaaggcgatc
     9721 atcaaggtta cgataactgg gaagataatc gcgaaggtca tggcaacata agatggaatg
     9781 atcaagaggt aagggaagcc attttcataa atccctttga tcatgtcttt gagtgtgcgt
     9841 ggaactggaa ttccattgtt aatgcgtttt gcaatcgtat gtgcatcttt gatatttgag
     9901 aaataaaaga gtacataaac gattacaaag attagatgga aggcaccacg aatcagcata
     9961 aagagggaat tatcacgacc tggtttgtca ccaagagtga tgaggttgct caattcaggg
    10021 gttgcaagtg ctaggaagta aaggacaaat acgatggtta caccaaggaa gataaaacct
    10081 ttggcttttt gtttattgta aatctgtcct aacccaggaa tgatagacag cagggctgct
    10141 ttactaggtt gttgcttttc catattaact cctttcatag gatactactt ttttataaga
    10201 aagctaaatt atttgtgtct ctattgataa attcaaaggg ggatttgatt tccacccccc
    10261 ttgaacaaat tttttattca ccaaattttt gtttgattgt ttctttgatc aatgttacag
    10321 catcgttagc agctgtttta gcatcttttt gaccacttac agcatcaaag agcatatttt
    10381 tcgctggatc ccaaactgca gacatttgag agatgtttgg cagtggttga gtgttcttga
    10441 actgtttgat aacagctgtt gtcaactcat cgtttttacc ttcagcgtat gaacgagcct
    10501 cagtattagc tgggatttcg ttagtcttat catataatac tttttgttgt tcagttgcaa
    10561 caaggaagtc tacaaatttt tgagaagctt caaggttctt aacggcttga ggaatgaccc
    10621 aagctttacc accaccgaat gcagcatatt cttttccatt tggaagagtt gggatagttg
    10681 caactccgta gtttacttta gcatctttaa aggcttgagc tttccaaggt ccgtcgatga
    10741 tagcagctgt tttaccttct tggaattgag tttggattaa gtttccagca ccttctgtat
    10801 cttgcatacc tttaggccat ttttcgtacc aagatttagc gtagttgata cctgcgatag
    10861 aaccgtcgtt tgcaagaccg atgtctttag cgtctttacc gttttggcca aagacgtaag
    10921 caccgttacc ggcaagaagt ccatatgtat agtagaagtt tgtccagtca gctaggaagg
    10981 cagtagtttt accatcttca ccagcgaatg cgtatttgct atctttagca aggttttcca
    11041 agtcagcaaa tgtttttgga gcatctttca ccaagtcttt gttgtagtac ataacaagtg
    11101 actcgataac ggcaggagca ccgtaaactt taccattagc agctgttaca agagatttag
    11161 ttgtgtcgtc tgttttagca ccatcgctca atttcacttc tgaaagttgt ccgtcagaac
    11221 caaggctacc tacacggtcg tatggagcca tcataacatc agggacatta ccagattggt
    11281 tgtcaagaga aagtttatca agacctccta gagcatcacc agttttaaga gtgactttta
    11341 ctccagcttc tttttcataa gctttagcaa cctcttcaat atagctctta tatccctcgt
    11401 ctacatatac agtgagttct ttgacttcag atgaaccaga atcagcaggc ttatcagcag
    11461 ttttgcttcc gcaagctacc aaaagcaagc tagcaagtgt agcagttcca agcaccgcag
    11521 tgctcttcat aaatttagat gacatagtgt attcctccca aagaatagca agttttattg
    11581 ataaggaaac gcaaacgttt tcctttatga gcttagtata gcacaaatag aaaacggttg
    11641 caagtatttt ttgtaaaaat tttaaaaaat ttttaagctt gatttgatag cataattttg
    11701 cattttaata gaagaaaagt gtgaaataga taagaataca gtatttttaa taaaaatata
    11761 tggaatctgt ctaaagaggg aaatcaggag gggctacctc cctgtttcta atccctatct
    11821 attttctata gacgtttgtg ctttgttgca tataaattca agctccctaa ggaggttttg
    11881 tactttgtag actgtctcgt gagagtcaaa ccttaggatt agatagtttt aagttatctt
    11941 tgctaaaatg agttagtctc cttaaaaata atcaaaaaag ttttttaaaa acgcttgcaa
    12001 ttatgcttga aaaggagtat acttataagt aacgcaaacg tttgcgtctg caaaatacgc
    12061 aacgttccat tattttaaca cacgaggtgc tattatgaaa aaacgtcaaa gtggtgtgtt
    12121 gatgcacatc tcttctcttc caggagctta cggaatcgga tcatttggtc aaagtgctta
    12181 cgacttcgtt gatttcttgg tccgtacaaa acaacgttac tggcaaatcc ttccattagg
    12241 agcaactagt tacggggatt ctccttacca atctttctca gccttcgcag gaaacactca
    12301 ttttatcgat ttagatatct tggtggagca aggtttgttg gaagcaagtg accttgaagg
    12361 agttgacttt ggtagcgatg cgtctgaagt tgactatgct aaaatctact atgcacgtcg
    12421 tcctctttta gaaaaagcgg tgaaacgttt ctttgaagtc ggagatgtta aagattttga
    12481 gaaatttgct caagacaacc aatcatggct tgagctcttt gctgagtata tggctatcaa
    12541 agagtatttt gacaatcttg cttggactga atggccagat gcagatgctc gtgctcgtaa
    12601 agcttcagca cttgaaagct atcgtgagca attggcagac aagttggttt accaccgtgt
    12661 gactcaatac ttcttcttcc aacaatggtt gaaattgaaa gcttacgcta acgacaacca
    12721 catcgaaatc gttggggaca tgccaatcta cgtagcggaa gattcaagtg atatgtgggc
    12781 aaatccacat ctcttcaaaa cagatgtcaa tggtaaggct acttgtatcg caggatgccc
    12841 accagatgag ttttctgtaa ctggtcagct ttggggtaac ccaatctatg actgggaagc
    12901 aatggacaaa gacggctaca aatggtggat tgaacgcttg cgtgaaagct tcaaaatcta
    12961 cgatatcgtt cgtatcgacc acttccgtgg cttcgaatct tactgggaaa tccctgctgg
    13021 ttccgataca gcagcacctg gtgagtgggt gaaaggtcca ggctacaagc tttttgcagc
    13081 cgttaaggaa gaacttggtg agctaaacat catcgcagaa gaccttggct tcatgacaga
    13141 tgaagtgatc gaattgcgtg aacgtactgg cttcccagga atgaagattc ttcaatttgc
    13201 cttcaaccca gaagacgaaa gcattgatag cccacacttg gcacctgcta actcagttat
    13261 gtacacagga acacacgata acaatacggt tcttggttgg taccgtaatg agattgatga
    13321 tgcgactcgt gagtacatgg ctcgttacac gaaccgtaaa gaatacgaaa cagtggtaca
    13381 cgctatgctt cgtacagtat tttcatcagt tagctttatg gcaattgcaa ctatgcaaga
    13441 tttactagaa ttggatgagg cagctcgtat gaacttccca tctacccttg gtggaaactg
    13501 gtcttggcgt atgactgaag atcaattgac accagctgtc gaggaaggtt tgcttgactt
    13561 gacaacaatt tatcgccgaa ttaatgaaaa tttggtagat ttaaagaaat aagacaataa
    13621 tcaggagaca actaaacatg ttatcactac aagaatttgt acaaaatcgt tacaataaaa
    13681 ccattgcaga atgtagcaat gaagagcttt accttgctct tcttaactac agcaagcttg
    13741 caagcagcca aaaaccagtc aacactggta agaaaaaagt ttactacatc tcagctgagt
    13801 tcttgattgg taaactcttg tcaaacaact tgattaacct tggtctttac gacgatgtta
    13861 aaaaagaact tgcagctgca ggtaaagact tgatcgaagt tgaagaagtt gaattggaac
    13921 catctcttgg taatggtggt ttgggacgtt tggctgcctg ctttatcgac tcaattgcta
    13981 ctcttggttt gaatggtgac ggtgttggtc ttaactacca ctttggtctt ttccaacaag
    14041 ttcttaaaaa caaccaacaa gaaacaattc caaatgcatg gttgacagag caaaactggt
    14101 tggttcgctc aagccgtagc taccaagtac catttgcaga ctttactttg acatcaactc
    14161 tttacgatat tgatgttact ggttatgaaa cagcgactaa aaaccgcttg cgtttgtttg
    14221 acttggattc agttgattct tctattatta aagatggtat caactttgac aagacagata
    14281 tcgctcgcaa cttaactctc ttcctttacc cagatgatag tgaccgtcaa ggtgaattgc
    14341 tccgtatctt ccaacaatac ttcatggttt caaacggtgc gcaattgatc atcgacgaag
    14401 caatcgaaaa aggaagcaac ttgcatgacc ttgctgacta cgcagttgtc caaatcaacg
    14461 atactcaccc atcaatggtg attcctgaat tgattcgtct tttgactgca cgtggtatcg
    14521 atcttgacga agcaatctca attgttcgta gcatgactgc ctacactaac cacacaatcc
    14581 ttgctgaagc gcttgaaaaa tggcctcttg aattcttgca agaagtggtt cctcacttgg
    14641 taccaatcat cgaagaattg gaccgtcgtg tgaaggcaga gtacaaagat ccagctgttc
    14701 aaatcatcga tgagagcgga cgtgttcaca tggctcacat ggatatccac tacggataca
    14761 gtgttaacgg ggttgcagca ctccatactg aaatcttgaa aaattctgag ttgaaagcct
    14821 tctacgacct ttacccagaa aagttcaaca acaaaacaaa cggtatcact ttccgtcgtt
    14881 ggcttatgca tgctaaccca agattgtctc actacttgga tgagattctt ggagatggtt
    14941 ggcaccatga agcagatgag cttgaaaaac tgttgtctta tgaagacaaa gcagctgtca
    15001 aagaaaaatt ggaaagcatc aaggctcaca acaaacgtaa attggctcgt cacttgaaag
    15061 aacaccaagg tgtggaaatc aatccaaatt ctatctttga tatccaaatc aaacgtcttc
    15121 acgagtacaa acgccaacaa atgaacgctt tgtacgtgat ccacaaatac cttgacatca
    15181 aagctggtaa catccctgct cgtccaatca caatcttctt tggtggtaaa gcagctccag
    15241 cctacacaat cgctcaagac attatccatt taatcctttg catgtcagaa gttattgcta
    15301 acgatccagc agtagctcca cacttgcaag tagttatggt tgaaaactac aacgttactg
    15361 cagcaagttt ccttatccca gcatgtgata tctcagaaca aatctcactt gcttctaaag
    15421 aagcttcagg tactggtaac atgaaattca tgttgaacgg agctttgaca cttggtacta
    15481 tggacggtgc taacgtggaa atcgctgagt tggttggaga agaaaacatc tacatcttcg
    15541 gtgaagattc agaaactgtt atcgaccttt acgcaaaagc agcttacaaa tcaagcgaat
    15601 tctacgctcg tgaagctatc aaaccattgg ttgacttcat cgttagtgat gcagttcttg
    15661 cagctggaaa caaagagcgc ttggaacgtc tttacaatga attgatcaac aaagactggt
    15721 tcatgactct tcttgatttg gaagactaca tcaaagtcaa agagcaaatg cttgctgact
    15781 acgaagaccg tgacgcatgg ttggataaag tcatcgttaa catttctaaa gcaggattct
    15841 tctcatctga ccgtacaatc gctcagtata acgaagacat ctggcacttg aactaatact
    15901 cttcgaaaat ctcttcaaac cacgtcagct ttatctgcaa cctcaaagcg gtgctttgag
    15961 caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa gatacaaatt
    16021 tatactaata catcttgtaa aaaagcgagt ttcaattgaa attcgctttt ttaaatgctg
    16081 tggatttggg tcaatcttgt ctaaaaatag ggaaatccta gatacagtga aggctttaaa
    16141 tgctggtttt tactgtcttc agccttatat tttttcgtag ttggttacct cacatctatt
    16201 gtattcgctt acataaagta ttataatata attgtaggaa agaaggtgtt tttatgatat
    16261 acacacttaa attggtgttg tttattatct ttcttgtaat aagcttgtta cctgataaga
    16321 tttttggaaa aaataaaaaa atttggaaaa tagtttttgc aatattgacg gcagtggcag
    16381 cattgtcatt tatgtactaa gttattttaa gaatgtaggg aaataaaccc tacatttttt
    16441 ttagtttttt ctgttttcta aattctattt atccaagagc ttcaacattt cttgcttctt
    16501 cgcttcaagt tctgcacgct tttcttcgat ttcggcatgt tttttctcga gttcagaaca
    16561 acttgcatca ttgctaaatt cttttcgcca tcaggagata gggtgagtct acatgtctat
    16621 tactcaccca aagcagtcct acaaagcagg aattttctgt tacttttttg gaaatagtaa
    16681 cgtttataca gctttgacac ttcgtatcaa agcgccaaac acactccgag ggatttacag
    16741 aaagcagaaa aggaatgatc tggtataaga tcattccttt tctctctttt tctttaagta
    16801 attatataca atgtacgacg aagtcgtcat tgcaatgctg atccaccacc taaagggaac
    16861 tttaaacaac attgataaga taaagaatat aaacaacgaa aatacgttat acccaattaa
    16921 ttttattgta tatctcatga ttaaaagtta atccttccgt tgttaggaat ggcatcattt
    16981 ttatcccata attgtgctaa ataagtcccc ggtgataata aattcatagc ggattctaaa
    17041 gcaacatcat ttacaaacca actacctaga tatctagaaa ttgctgaacg aatagcactt
    17101 tttgctgcat gttttccttt tactttaatt agatttgcaa ggcctgcagt agttcctcct
    17161 aatgctaaag ctattgcagt atctaataga gcacccattt gattaactgt aataccttgc
    17221 caagctgctc taaatggaga gtatgtaggt gggattgtat aatcgccttg taattgtcgg
    17281 ttaattactt ctttgatcca ttgttgtgag acgtctggat gaaaagattg gatttcgttt
    17341 gcaagtgtat tgatttgttc ttctgttaga gaagtgacag gttgaagttc catatttgtt
    17401 tcaatttgtg atacttgttc agaagcgtat acagctgaaa cacttggaat cgctgataca
    17461 attaacacaa ttgacgtcaa aaaaaccgaa ataaatttca ttaatttgtt catgagcttt
    17521 tctccttttt atttgtatct gcttacattt tattatatac tgttattata gtcaagaaaa
    17581 atatgctatt atgttaaaaa aatattttta aaaatataaa tggacggatt tattttggat
    17641 tttatttgtt attttgacct gcctctatat tggtaaccat gatttgttta ctttcaatca
    17701 tcaagaattc tcttttcgtg gtagcgtttg gggtctggta ctggccttat atcacttatt
    17761 gttcattgat aagtttgtaa tttcgaatcg aaaataaaga ttagaactat gattgactgg
    17821 ctacttttaa tattgatttt ggaggaagat tttgtctcta ttatttatta ttttaaattt
    17881 atctattttg tacaagattt attctttgag acgggagaaa tcgaaatact tgatttatac
    17941 ggcctatatc atatttgggg taaatgtagt atatggtatt caatggttat taagagaact
    18001 gatttcaact atttcccctt aatgtgtatg gaaactataa caaaacgcat aagattaagg
    18061 tttgtgtacc tgttcttatg cgtttttata atattgaaga ttttcggtaa gttttatacc
    18121 tttgggaagt ctagtttaga atgctttccc aaccaaaatc tctgcttcga tggtaatctc
    18181 tgtcagttga ctccagtcaa tcttgctctg gtcaacgtga aagaggagag gagtcatact
    18241 gagtagggct tggagttgtt ctgctgtgat agtcttagtc agagaggcag tttgactaga
    18301 taggatggta aagtgttcct ggaaatgctc cttgatatct tggttagaat actccttgtt
    18361 tgtcagctgg tcctgtactc tttgacggat ttctttgagg tgattttcag ttgggataac
    18421 ctttatcaag ataccgtctt tggataaaac gcgacgaaat tctccatagt tggcaggtga
    18481 gaagatatca agcagaatat ccatgttagc gtcttttata ggaagtcgtg ccaagtcgcc
    18541 aacaaaccaa ttgactgccc agttgggttc acttttagca gcgatttgga ctgaatcttt
    18601 ggagatgtca aaggcataga aagttttttc agagtgactt tcttgtagtt tgcgagaata
    18661 gaatccttca ccacaaccga tatccaaaat tgttgtggta gtttttgagc ttgcaagcaa
    18721 gtcagataca gcatctaaga tagcttggta aaagccggct tctaggattt gttgacggtt
    18781 ttgaaaattt tccttgttat agttagcaga ttgcttgatt tgaggtgcta gattgacata
    18841 gccaaatttc gccaagtcaa aagaatgacg gttgcagcac ttgaaattag tctctaacag
    18901 agtcagattt tcttgacaga taggacaggc aaaggcagtc gcagaagcaa aacgctgaag
    18961 tttgggcttg agatttgtat tcatagttta agtgtatcaa aagaggcaaa tgaaagcaac
    19021 tttaggaata agtagatggg agattcagta gaaataaaac taattctcca atttatagaa
    19081 tgaaattgct tttatatcta aattgctata taataatgat aaggaggaaa taagtatgtt
    19141 aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct tcattatttt tgggtggtgt
    19201 cgcatttggt acccttggtt tgaaaatctt agcaagtaag gaagctaaaa aaggttattc
    19261 taaagctttg gctaaggctt acaagttgaa agacgagcta gatgcatctg tttctgttgt
    19321 gaagcaacat ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc aagagaaaaa
    19381 agaagagcaa ttagatagcc ttataggtga ataatatgtc ttttaaagtg ctacatagag
    19441 gataccaaca tatccgacta tcatcttctt tttcacttac cttggatatt caagactatc
    19501 ttcgttcctt ggcgagagat gaaaagggga ttgagtctat ccagttttac atggatcaac
    19561 agcactttac tctacgcata aaagaaggct tttctgtatt agataatgca gaagcctttt
    19621 taaaaagaat tgataaaggg aaagtttctg agttgatgac tcttcccatt cgtagagaag
    19681 agagtgctta ttctattgtt tcaggtgcag cggttaagcg tgtacttttt cgtagttttg
    19741 tgccgtatcc tattcgctat atatggactt gttatcaggc tttgggttat attagagaag
    19801 cctatcaaac actagcgcgt aaggaactaa cgatggaagt cttggactgt tcggctattt
    19861 tattgtcttt gtttatgaac caatccaaga cagctagcaa tatcatgttt atgcttgatt
    19921 tggggaatca tttagatcag tggtccttga aaaaaactgc aacagattta gaacagagtc
    19981 ttcttgcaaa agagagcgat gtattcctag tacagggcga tacggttgtt agtatcaaga
    20041 gttccgatgt tcaaatagga gatgtcttga tcttatctca aggaaatgaa attctgtttg
    20101 atggacaagt agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca ggagagagtt
    20161 ttccagttga aaaaagagag tctgatttgg tttgtgcaaa tacagtatta gaaactggag
    20221 agttacgcat tcgtgtaaca gataatcaga tgaacagccg tattttacag ctgattgagt
    20281 tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc aagatggcgg
    20341 ataaagtcgt caaatataat ttcttggggg ctgggctgac ttacctattg acaggttctt
    20401 tttctaaggc tatttctttc ctattggtcg atttctcctg cgctttgaaa atctctactc
    20461 ctgtagctta tttgacagtt atcaaggagg ggttgaaccg tgaaatggtg attaaggatg
    20521 gagatgttct ggagaaatat ctggaagttg atactttctt gtttgataag acaggaacaa
    20581 tcacaactag ttatcctata gttgaaaagg tgttaccttt tggagactat aataaggaag
    20641 atattctcag aatcagtgcc tgtcttgagg aacacattta tcatcctatt gctaatgcca
    20701 tcgtcaagca agctgagata gagggaattg aacatgagga aatgcatggg aaactccaat
    20761 atatcgcaag taaggggatc aaatctcata tagatggcca accagttctt attgggaatt
    20821 atgtcttgat gcaggatgag cagattcata tcagttcaga acaaaatgct ttaattgaag
    20881 agtacaagag tcactacaat ctcttattct tggcttatca aaatgaattg attggaatgt
    20941 tctgcattca tactcctttg agaaaagaag caaaaacagc cttggataaa cttaaggcac
    21001 aggggaaaaa attgattctg gcaacaggag acaccttgat taggacagag gaattagtca
    21061 aagatttgcc ctttgatcag gtctatacag acttgaaacc tgatgggaaa tttgagttag
    21121 tagagaaact gcagaaagca ggtcacacta tcttgatggt tggagatgga ttgaatgact
    21181 cagcggcttt aactctatca gatatcggtg tggtgatgaa tgagagtgca gatatttcta
    21241 agcagatgag tgatatctta ttgttagata atcgtttgga tttcttccaa gagttggatt
    21301 cgttatcatc atctttgcaa acactcatca agaaaaatat tcaagatacc gttgtcgtaa
    21361 atagtagttt gattggcttt ggcttattta attggttcag tccttcaaat ctctctatct
    21421 tacataatct aacaaccttg cgcattgtct tgcgtagctt gtctattaaa aatagataga
    21481 tgagagttat taacagcaaa aaggagttac ctttctcgag gttaactcct ttgtttatag
    21541 ataaatgttg aatagtttag taagtcaata caaagtattt tttcttccca cgacggataa
    21601 cagtcagttc attttctaac ttatcagcgt cactcaagac atagtcaagg tcttggatgc
    21661 ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc acgggcttgg cgttttgagt
    21721 taactatacc agatgagacg agcagttcca cgatattgtt gttttcgtct gcctgtactt
    21781 ggtagtttgg cacaccacga agtccttgtt tgagctcttt gacagaaagg tttttgatgt
    21841 ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt gtaggcttct tctccgtgaa
    21901 caagtgtaac aacttcacga gccaagactt tttgagccaa gcgttcgtgt ggcgctgctt
    21961 caaattgttt acgaatatct tcaatctcat caagtgacaa gaaagtaaag attttcaaga
    22021 agcgaatagc gtcagcgtcc atcacgttca tccagaattg gtacatttcg tatggagaag
    22081 tcttttcggg attgagccag acggcatttc cttctgattt accaaatttt ttaccagttg
    22141 catctgtgat tagtggaaca gtgataacgt gaccagtctt gtccgcctta cgacgaagca
    22201 attcggtacc agctgtcata tttccccact ggtcagaacc accgatttga agagtgacat
    22261 tatggtcttg gttaaggacg aagaagtcgt acccttgcat gatttggtaa gcgaactcag
    22321 tgtaagaaat tcctgtttcg atccgttttt taacagattc cttactcatc atgtagttga
    22381 ccgtgaagta ttttccaatg tcacggagga agtcaatgaa gctgatgctg ccaaaccagt
    22441 cgtagttgtt gaccatgaca gccttgtttt cgccattttc aaagtcaaga aaacgagaaa
    22501 gttgtccttg gatagacttg acccagccat ctactgtgtc ttttgtttgg agactacgtt
    22561 cagcatcttt gaaggacgga tctccgatga gacctgtagc accgccaacg agcgcataag
    22621 gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg tggcctaggt
    22681 gaaggctgtc agcagttgga tcgtagccag tataataaga aacttgacct tcttctaggg
    22741 ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa accacgctct tttagctcat
    22801 caaaaatgtg catgtgtctt ttctcctttt taaaattatt gtttctacct attgtatcac
    22861 aaacttgggc aatagcctag cagaataggg aagaaagtgg ctattttatt gaaaatttcc
    22921 cttttgtggt ataatagata aagtgaggaa atccatgcaa aatcaattaa atgaattaaa
    22981 acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag ctagacctgg
    23041 caagaaaggt tcaagtacca aaaaatctaa aaccttagat aagtcagcca ttttcccagc
    23101 tattttactg agtataaaag ccttatttaa cttactcttt gtactcggtt ttctaggagg
    23161 aatgttggga gttgggattg ctttggggta cggagtggcc ttatttgaca aggttcgggt
    23221 gcctcagaca gaagaattgg tgaatcaggt caaggacatc tcttctattt cagagattac
    23281 ctattcggac gggacggtga ttgcttccat agagagtgat ttgttgcgca cttctatctc
    23341 atctgagcaa atttcggaaa atctgaagaa ggctatcatt gcgacagaag atgaacactt
    23401 taaagaacat aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg ggaaatttgt
    23461 aggtttgggt tcctctagtg ggggttcaac cttgacccag caactaatta aacagcaggt
    23521 ggttggggat gcgccgacct tggctcgtaa ggcggcagag attgtggatg ctcttgcctt
    23581 ggaacgcgcc atgaataaag atgagatttt aacgacctat ctcaatgtgg ctccctttgg
    23641 ccgaaataat aagggacaga atattgcagg ggctcggcaa gcagctgagg gaattttcgg
    23701 tgtagatgcc agtcagttga ctgttcctca agcagcattt ttagcaggac ttccacagag
    23761 tcccattact tactctcctt atgaaaatac tggggagttg aagagtgatg aagacctaga
    23821 aattggctta agacgggcta aggcagttct ttacagtatg tatcgtacag gtgcattaag
    23881 caaagacgag tattctcagt acaaggatta tgaccttaaa caggactttt taccatcggg
    23941 cacggttaca ggaatttcac gagactattt atactttaca actttggcag aagctcaaga
    24001 acgtatgtat gactatctag ctcagagaga caatgtctcc gctaaggagt tgaaaaatga
    24061 ggcaactcag aagttttatc gagatttggc agccaaggaa attgaaaatg gtggttataa
    24121 gattactact accatagatc agaaaattca ttctgccatg caaagtgcgg ttgctgatta
    24181 tggctatctt ttagacgatg gaacaggtcg tgtagaagta gggaatgtct tgatggacaa
    24241 ccaaacaggt gctattctag gctttgtagg tggtcgtaat tatcaagaaa atcaaaataa
    24301 tcatgccttt gataccaaac gttcgccagc ttctactacc aagcccttgc tggcctacgg
    24361 tattgctatt gaccagggct tgatgggaag tgaaacgatt ctatctaact atccaacaaa
    24421 ctttgctaat ggcaatccga ttatgtatgc taatagcaag ggaacaggaa tgatgacctt
    24481 gggagaagct ctgaactatt catggaatat ccctgcttac tggacctatc gtatgctccg
    24541 tgaaaagggt gttgatgtca agggttatat ggaaaagatg ggttacgaga ttcctgagta
    24601 cggtattgag agcttgccaa tgggtggtgg tattgaagtc acagttgccc agcataccaa
    24661 tggctatcag accttagcta ataatggagt ttatcatcag aagcatgtga tttcaaagat
    24721 tgaagcagca gatggtagag tggtgtatga gtatcaggat aaaccggttc aagtctattc
    24781 aaaagctact gcgacgatta tgcagggatt gctacgagaa gttctatcct ctcgtgtgac
    24841 aacaaccttc aagtctaacc tgacttcttt aaatcctact ctggctaatg cagattggat
    24901 tgggaagact ggtacaacca accaagacga aaatatgtgg ctcatgcttt cgacacctag
    24961 attaacccta ggtggctgga ttgggcatga tgataatcat tcattgtcac gtagagcagg
    25021 ttattctaat aactctaatt acatggctca tctggtaaat gcgattcagc aagcttcccc
    25081 aagcatttgg gggaacgagc gctttgcttt agatcctagt gtagtgaaat cggaagtctt
    25141 gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa gaaaaagaag tagaggtcac
    25201 aggttcgact gttaccagct attgggctaa taagtcagga gcgccagcga caagttatcg
    25261 ctttgctatt ggcggaagtg atgcggatta tcagaatgct tggtctagta ttgtggggag
    25321 tctaccaact ccatccagct ccagcagttc aagtagtagt tctagcgata gcagtaactc
    25381 aagtactaca cgaccttctt cttcaagggc gagacgataa ttctctaaat gaagtggcca
    25441 atcaatggat tgccactttt ttcctttcgt gttacaataa gggtatgaat cagtatcaga
    25501 aaaagattgt taacggaaaa atttattcgc tcctatccgg cttaatatgg ggaatctgtg
    25561 gaattttagg agagtacttc tttactcatt atcaggtgtc ttcgggctgg attacctcta
    25621 tgcgtttgac actggcaggg agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc
    25681 aagtgctaga tatttggcga gacaagaaaa attacctgcc ctttttagcc tatgctattt
    25741 tggggatttt ttcagttcag tattttttct atctctgtgt agaatactca aatgctacga
    25801 cagcaactat tttacagttt attagccctg tctttatcct cttttacaat cgcttggttt
    25861 atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg ctgggtgttt
    25921 gcttgatggc gacaaaggga gaactctctc agttatccat gacgccgcta gctcttataa
    25981 caggtttgct gagtgccatg ggtgttatgt ttaatgttat cttgccccaa ccttttgcta
    26041 agcgttatgg ttttgttcct acggttgggt gggggatgat tttggcaggt ttgtttagca
    26101 atgtcctctc gccggtttat cagctttcct ttactcttga tatttggagt atcttgattt
    26161 gcctcattat cgctttcttt ggaacggctt ttgctttttt catttccatg aaggctgtgt
    26221 ccttggtttc tcctttggtg gtttccgtta tcagtgccag tgaacctctc tcttctgctc
    26281 tcttgagtgt tttgttctta ggattagtag tggattggtc cctccttcta gctatagtct
    26341 tgattatttt acccatgata tttttgtcta tagaagaagc gaaagaaagt agataaaaag
    26401 tcttttctta attctaaaag tgtgctatac tagaatagtc aataaaacac ggggagatag
    26461 ttgtgaagag tgtttttagg ttgtatcggt aggggcttgc ttttaccgac agcacgtttt
    26521 atctcacaac cctaaaaaat catacctaaa aacagacaaa aaggtttcaa atttgaggcc
    26581 ttttttggta gaataggtat cattataacg aaccaggagg cacctatgac tgctacaaaa
    26641 atgaacgctc aagaaattat ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa
    26701 gtaacctttg aggggcaact cgcaactgct gtgcctagct ctgttgtcaa actaggaaat
    26761 gtcctattcg gagactggaa ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa
    26821 gattatgttg tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga taagcgtgct
    26881 atcaacgctc gtatcgagcc aggtgctatt atccgtgacc aagtggaaat tggtgacaat
    26941 gctgttatca tgatgggagc tgttatcaat atcggtgctg aaatcggtgc tggaaccatg
    27001 attgacatgg gtgccatcct tggtggccgt gccatcgttg gaaaaaatag ccacgttggt
    27061 gcaggtgcag ttttggcagg tgtgattgag ccagctagtg ctgaaccagt ccgtgtcgga
    27121 gacaatgttc tcatcggggc taatgcagtg gttatcgaag gagtccaaat cggtagtggt
    27181 tcagttgtcg cagcaggagc tattgttacc caagatgtcc cagaaaacgt ggtagtagca
    27241 ggtgttccag ctcgtattat caaagaaatt gatgcccaaa ctcaacaaaa aacagcgcta
    27301 gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca
    27361 gcctctttct gctatatcgg aggacagata gatgttagat ttgattcaga ctagacgaga
    27421 tttacaccag attccagaga ttggcttgga ggagttcaag actcaggctt atttgctgga
    27481 tgtgattgag aaattgacta cgggcaagga ttttgttcaa attcgtactt ggcggacagg
    27541 gattttggtc tacctgcagg gaagtcagcc ggagcgaacc attggttggc ggacagatat
    27601 tgatggcctg cctatcgtcg aacaaacagg tctacctttt gcttctcaac accaaggtcg
    27661 catgcatgcc tgtggccatg attttcatat gaccattgcc ttaggctgtc ttgagcgcgc
    27721 ccttgaggag caacccaaga ataatctgct ctttctattt cagcctgctg aagaaaatga
    27781 agctggtggt atgctcatgt atgaggacga tgcttttgga gattggttgc cagatcaatt
    27841 ttatggcctc catgtccgtc cagatttgaa agtcggccag attgcgacta atactcatac
    27901 actctttgca ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc
    27961 ttttcctcat gaagccaatg acgccttggt ggcggctagt tactttgtga cccaagtgca
    28021 gtcagttgtt agccgcaatg tcaacccaat cgagggagca gtggtgacct tcggcgtttt
    28081 tcaagctgga accaccaaca atgtcatcac agacacagct tttttacatg gaactattcg
    28141 tgccttgaca caggacatga gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagg
    28201 ggttgcagct gcctttgata tggaagtcga agtggaactc aaacaaggtg gatacctacc
    28261 tgttgagaac aatccagcct tggcgcgtga actgatggac ttctttgacg aaaaagacgg
    28321 aatcgagttg attgatatcg aacctgctat gacaggcgag gactttggtt atctcctttc
    28381 aaaggttgat ggcgtgatgt tttggctagg tatcgatagt ccctacgctc ttcatcaccc
    28441 tcaaatgagt cctaaggaag aagtcttagc tattggggtg gctgcggtgt ctagtttcct
    28501 gaaaaagaag gcagcagaat agagggcttg tctatgaaat cggaattacg caagcaagtc
    28561 ttgcatgaaa tgaaggctat atctcaagag caaaaacagg ctatagacca agctttaacc
    28621 gagcggcttt tacaccatcc cttctaccaa gaagccaagg tcatcgcaac ctacctctct
    28681 ttttctcatg agtttcaaac gcgggaactg attgagcagg cgctgaagga cggcaagaag
    28741 gttttaatac ccaaaactta tcccaagggg cgcatggagt ttgtggccta tgatccgcaa
    28801 cagttggtaa aaacttcctt tgccttactg gagccacagg gagatgtgga agtggtggat
    28861 gcatctcaga ttgatttgat tcatgttcct ggtctggctt ttacgacgaa aggatatcgg
    28921 ataggatacg gtggaggcta ttatgaccgc tatctggaac atttttctgg tcgtactttg
    28981 agtacgatat atccttgtca aattcaggac tttatacctg aaaaccatga tattcctgtt
    29041 caggaggtat taattgatga aggaaatctt tgatagacgt taccctgtga cgagtttctt
    29101 cctcttagtg acggccttgg tatttttact aatgttggtc actgcaggcg gaaactttga
    29161 cagggcagat acattatttc gatttggagc catgtatggg ccagctattc gcctctttcc
    29221 cgagcaggtt tggcgtctct tgtctgccat ttttgttcat attgggtggg aacatttcat
    29281 tgttaatatg ctttcacttt attatcttgg aaggcaggta gaggagattt tcggttctaa
    29341 gcagtttttc tttctctatc ttttatcagg aatgatgggc aatctctttg tttttgtatt
    29401 tagtcctaaa tccttagcag caggcgcctc tacctctctt tatgggctat ttgccgcgat
    29461 tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc aatcctatct
    29521 gacacttttt gtggttaaca ttattggaag tgttctgatt ccaggaatca gcctagcagg
    29581 ccatatcggt ggtgcagttg gtggcgcatt tctagcagtt atctttccag ttagaggaga
    29641 aaaacggatg tataacacca gccagagatt aggagcggta gtcttgttcg taggactcgc
    29701 cattttgctt ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa tttgtgtaat
    29761 gaaaaaagat aaggcatttt ttgaacctta tctttttatt ttattccttc tcagtcaatt
    29821 cttttccaag ttggatgagg taattcttca aatcatcttt gacttgtgga tgtttgaggg
    29881 cgtagtcaat agatgttttc ataaagccaa acttatcccc aacgtcgtaa cgagctcctg
    29941 taaattcacg ggcaaaaaca cgctgtgttt tattaagagt atcgattgca tcagtaagtt
    30001 ggatttcatt tccagcacca ggagcttggt tttcgaggat ttggaaaatt tcaggcgtga
    30061 ggaggtagcg tccgataata gcaaggtcgc taggagcgtc ctctggagct ggtttttcaa
    30121 caaaggtttc aacactgtaa agaccatctt ttccttcgcc ttgcggagca ataaccccgt
    30181 aagcagatac ttcgtcatga gggactggca tgacagcgat agtagacgcg tgggtacgct
    30241 tgtagtcatc catgagttgt ttggtaagtg gaacagcctt ttcgtctgtg atatccatca
    30301 agtcatcacc aagcataacg acaaaaggtt catttccgac gaaagccttg gcttgcaaaa
    30361 cagcatctcc gagaccgcgt ggatgagttt ggcggataaa atgcagacgc atgccagttg
    30421 tttcatcaac tagcttcaaa agatctgttt tccctttttc tttgaggtta tattccaatt
    30481 cgaagtttga atcgaagtgg tcctcaatag aacgttttga tttaccagtg acaactagaa
    30541 tatcttcaat acctgatttg agagcctctt ccacgataaa ctggatagtt ggtttgtcta
    30601 cgattggcaa catttctttg gcaagggcct tggttgctgg taaaaatcga gttcctagtc
    30661 cagcagcagg gataactgcc tttctaactt ttgatgtcat aaaaatcctt tctatagagg
    30721 gttaagacca ctcattttct gctttaaatt cattgttcat gatgtcataa atggcatctt
    30781 tgatattggt tccgtgataa ataacttggt aaatagcctg tgtaatgggc atatagactc
    30841 caagttcttg ggctagttca taggctgctc gagtcgttga aattccttcg attaccatgc
    30901 ccatattagc ttctatatca gctagggatt ctcctcgtcc gagagcatct ccagctctcc
    30961 agttacgaga gtggatggaa gttcccgtta cgatcaaatc tcccacacca gataagccgc
    31021 tataggtcaa tggactggcc ccgagtgcta cccctaggcg ggtgatttct gctaaacctc
    31081 gagcgatgat ggctgcctta gcattatcac caaatccaag accatgtaaa gctccagcac
    31141 cgacagcaat aatattttta agagcaccag cagtttcaac cccgataaca tccgtattgg
    31201 tataaagtcg gaagtagtga ttactaaata gctcctgaac gtattgagct gtttgtaaat
    31261 ctttagaagc agcagttatt aaagttaggt cacgcacaat ggtctcttct gcatgactag
    31321 gccctgaaac aacgacgata tcactacgga gatgttcagg aatttcttct tcaagaatgg
    31381 ttgataatcg tttatggcta tcaggttcta atccctttga tgcgtgcatg atgataacct
    31441 tatggtccaa ggtttgtgca acttgctggg caacaagtcg tgtcactttt gttgggacaa
    31501 caaacaaaat cgcatccaca tttttcaatg tttctgctaa gtcggtgtag gcaatgatat
    31561 tttcgtctag aacgacatct ttaaagtagt gcttattagt atggtgtgta ttaatttcat
    31621 tgatttgctc gggaagattt ccccaaatac gtacctcgtg tccattgtca tttaagactt
    31681 gtgaaagggc ggttccccaa gaaccaggcc ccaagacggc gacggtttgt ttttccatga
    31741 tttcctcctt gatagatttc tttctcttat tctatcatat tctaggggat tttgcacttg
    31801 cattactggg gtatggtgga aaaatacaca aagaccgaga tgaagggata aactcttagt
    31861 ctttagttaa agtgagaaga aatctgatag atagtttgat tcagtatatg cttataatag
    31921 aggtaaacaa ctcaggaagt tcttgtaggt tgcgagagtt tggcgaaaaa attaaaagat
    31981 tacgtttggc taaaaaaatc agtcgttcag aattttgtgg tgatgagtct gaattaagta
    32041 tccgtcaatt aattagaatt gaaaatggag aatccagacc aacactaaca aagttaaaat
    32101 atattgctga acgtttggag gttgaagatt acaagttgat gccaagttat atagagttgg
    32161 ataaggaata cctagaattg aagtatttct tgatgaggac tcctacatac gaagatgaaa
    32221 ctatcgccca aaagaaagag agtgtttttg ataagatttt tgaagagtat tatgataggc
    32281 tacctgagga agaaagattt atcatcccaa attattcata tctagcacta gcgaactaca
    32341 cagttcaaaa attaccagaa aagctagttg aaatactgtc cttctggtga ttttgcttaa
    32401 tttctgatgt tcgagacatg attgaggaga tttgtcttga ttttttccta aaaaagggca
    32461 gactcctccc ttggtttgat gctcgatttt taaaataagg tgacttattc tgttaggcag
    32521 ttttcccctg ccctctagct ctatatggaa cagggagtat cagatttatc tggcagattg
    32581 tatcaaataa ggcttgaaac tgttttgaat aggcgtatag acttgagaat ttgagaatat
    32641 gtcgtctagc agtagagaca tattttccgg caatatgaag gaagagacgt cgaaaacgct
    32701 tgatagtcaa ggcctttact tcatcaccag ctagctgctt taaaaagagg tagagattat
    32761 aagccagaca gcccatcatc atacgtactt cattcttaat catggtcgaa ctatctgtct
    32821 tatccccaaa gaatcctgct ttcctttctt tgataaagtt ttcagcattc cctcgttcac
    32881 gatagaattg aaacagctcc tcactatcta cactgcttaa attgttcaaa tgaacttttt
    32941 tacaaccata aaaaagagca cttaatcgta ctcttctctt ttaaggatta gttgaattaa
    33001 ttcaaatcca ccagttctcc tgtttctagg tagactaggc gttcacaaat gttagcaatg
    33061 taatcagcga agcgttccag atgccctatg atataaaggt attgagttcc attgggaatt
    33121 gaggtttctt ggtctttcat aagtccaatg atttcctttg ataaggcata ataatattgg
    33181 tcaatctgtt catctttttg agcaatacta atagcttttg aggcttggtg caaaggaaag
    33241 gcaaccaata aatcggctag catgctgagg gataatttac ccatttggtg taactgttct
    33301 tcgtcagggg ctagttgatt ttcttttagt tgcaaaacag ctttagcaat gcctgccata
    33361 tggtctccca tacgttcaag gtctgaacaa gaagacatga tgctaatcac aaatcgaagg
    33421 tcagacactt gtggctgctg caaggccaac aaacgggcac aggtcaattc gatagcgctt
    33481 tgaccttggt tgatagcatg atccttattg ataattagct ctgccatctc cttgtctttg
    33541 gaggctaagg ccagtaaggt ttttgaagct gtttcaagga caagttgccc tagtcctaaa
    33601 aaggattgtt ctaattcatg caattctaag tcaaattgat ttctcatagg tttttccttc
    33661 cttatccgaa ccgtcctgaa atatagtctt ctgtgcgctg atcttttgga ttggtaaaca
    33721 cgtcaacggt gtctccaaat tcgcaaattt ctcctgttaa gaaaaaagca gttttatctg
    33781 aaatacgtga agcttgttgc atgttatggg taacaatgat aatcgtataa tcctttttta
    33841 gttgctgaat gaggtcttca atttttaaag tggagatagg gtctaaggct gaagtcggct
    33901 catccattaa cagaacatca ggttctactg ctaaagctcg cgcaatgcaa aggcgttgct
    33961 gctgaccgcc tgataaggac atggcactct ttttaagatt atctttgact tcgtcccaaa
    34021 tggctgcccc ttttaaagat ttttccacta aggcatctaa ttgttttttg tctcgaatac
    34081 catgtgtcct tgggccataa gccacgttat catagataga catggcaaag ggattaggct
    34141 gttgaaaaac catccctaca cgcttgcgta gctgattaag gttgaatttg ctactataaa
    34201 tatcttgctc atctaagagg acttggcctt caatatggca agaaggaacc aaatcgttca
    34261 tccgattaag ggtttttaga aaagttgatt taccacaacc agatgggcct atcaaggcag
    34321 taatctgtct ttctggtaat tgaatcgaaa tattttttaa ggcttgaaaa tccccgtaaa
    34381 ataagtctag gtgtctgact gaaaatgttc ccatactagg aagctccttt cacaagtttt
    34441 cgagataata agcttgatag agtatttatc attaaaacag taataatcaa aatcacaccg
    34501 gtagcatagg cttcattgac atgtagcccc tcacttgaca gcatatacat atgcagggct
    34561 agagaacgac ctgaagacat gagactactt ggcgtattgg tagaggtacc taatgtatac
    34621 atgagggcag ctgtctcacc aacgatacgg ccaatagcta gtatcactcc agctaaaata
    34681 cctggcatgg caactggtag aacaattcta aaaacagtcc gtaacttacc tgccccaagt
    34741 ccataacttg cttgacgcat gctatcacta acagataaaa gggcttcttc tgttgagcga
    34801 ataatgactg gcaacaccat gatgactgag gttaagattc ctgataacag agagtattga
    34861 aaacctaaga agactacaaa gaagagcatg ccaaacagac caaaaacaat ggaaggaatc
    34921 ccagacaagg tatctgaggc caatcgcatg attttaacac aaagggaatc tttttttgta
    34981 tattccacaa gataaaaacc agcaaaaatc cctatgggca aggctaaaag aagagcacca
    35041 aagaccagaa taacggtgga aataatcgct ggcataaggg aaatgttctc agaagtataa
    35101 gtccaagaaa agagggatag acttagatga ggtaaacctt tgatgaggat aaaaccaatg
    35161 attaaaaaga gagagccaaa ggttaaagct gaaaaacaat aaacgagaag ttttagcagg
    35221 tatttactca taagatgatt ttcctttcaa gtaggcaaag taggcattaa tcaagagaat
    35281 aaggaaaaag agaactgctg aggttgcaat aagggcttcc ctatgctgac ctgatgcgta
    35341 agccatttcc agaacaatat tggttgttaa ggttctggtt cctgaaaaga gtccacttgg
    35401 aataatcggc tggttgcctg ccaccaaaat aactgccatg gtttcaccta ctgcgcgacc
    35461 gatgcctaaa ataactgctg ataaaatacc agatctcgca gctggcaaga tgacactaaa
    35521 aatactccgt tcatgactag ctcctagagc caagctacca gaataatacg ttttgggaac
    35581 tgttcggata gcagattctg acaaactgat aatggttggc aaaatcatta ttcctaatag
    35641 taacgaagcg gttaggacac tcatgccatt tcctaaaaag cttctaatcc aaggcaccaa
    35701 taattgtagg ccgaaaaaac cataaacaat agatggaatg gccgccatca agttgatagc
    35761 tgattttaag aagccataga cgggctttgg acaataataa accataaaca ccgatgtcaa
    35821 gatgcctgtt ggcaccccaa tcacaatcgc tcctaaggta attaataagg aaccaacgat
    35881 cattggtaaa ataccatagc ttgccggaat gttcgttggc gaccaatcac tgcctaataa
    35941 aaaacgggca aagccgtagt tagccatgaa aggtaagcca ttactaaaaa taaagaaaca
    36001 gattagcaaa atagctacaa cagctactgt tgcactcatg aaaaaaattg ccctaaaaac
    36061 tgcttctttg aaggcttgtt ttatcacatc ttgtcctttc tagtgaagaa agtaagggag
    36121 atacgacacc tccctacttg ccttctttat cttattgtac gatgaaacgt ctgcatctct
    36181 ttagagattt atggagcaaa cattttattt aatcttgtcc caggtggtta atttgccact
    36241 aaaaacgtct gcaagttcag ccatactgac ttggcttgcc ttattgtcat tattgaccac
    36301 aacagcaata ccgtctaaag caatagcatc atgggtgaga ctcttacctt cttcaggagt
    36361 taattcccta gaaaccatac caatatcagc ggttttctcc ttaacagcgg taatacctgc
    36421 tgaagaccca ttagaggtaa tatcaatcgt aacttctgga ttttcttttt tataagcttc
    36481 tgctaatttt tccattaaag aagatactga agtggaacct acaacagaca acttgcctga
    36541 taagtgttgg cttgtatatt ctgtggtttc agttttagct tcaataaatt tattatctgt
    36601 gaccacttgt tgaccttgtt tggagtggat aaagctgata aaatcttgac ctagcttgga
    36661 aagattagaa gaccaaacaa tgttgaaggg acgttgaaga gggtattcac catctaaaac
    36721 tgtgtctcga ctagccttga caccatcaat ctctaaagcc ttgacagatt tcgttaaaga
    36781 tcccaaggag atgtagccga tagcattagc attcccttga actgctgaga gaacaccttc
    36841 tgtactattt tgaatcacag ctgttttggc agtgttgtca atttttttat caccgtcttt
    36901 tttgagaatc cctgtgattt ctgtgaaggc accccgtgtt ccagagccat tttctcgtga
    36961 aatcacctca atcgttcctg aagctgactg tttggaagca gctgactgat tgccacaggc
    37021 aacaagccca aatcctgata agccaatggc tgcaagagta agcatttttt tgaatttcat
    37081 aataatcacc tttatctcta tgtatttttc ttgtgtaggc ttactacatt tatagtctaa
    37141 caagtctttg taaaggttta tccctgattc atgtaaagat tgtgtaaaga atcaaaaaaa
    37201 gccacttttg aaaaatggct gctcctaaaa atagctttaa aaattattag tcctgtgcga
    37261 aagattggtt aggaagaaaa atcgtgaagc aactgcctct gccaagctga ctcgtcaccg
    37321 tgacttggcc acctaataat tgactgagtt ctttgacaat ggcaaggcca agaccagtgc
    37381 caccagtttg tctgcttcga cctttattaa ctcggtaaaa acgttcaaaa atacgatcct
    37441 gctctaattg actaatacca atccctgtat ctgatacaga aatcttaatg ccttcgttca
    37501 ccttttgggt cttgacctca atttttcccc cttgttcagt gtaacggatg gcattggata
    37561 aaagattgag taagatttgg gaaagtaatt gactatctga tacgagggtg acatcatctg
    37621 gcacctgcac ctttagctgt aaatccttct tcttgagctg aggttgcaag ctttgagtca
    37681 aatcctgtac aaattcagcc aaagaaaggg tcgtccattg tataggcatt tgttgagcct
    37741 tagataaggt aagaagatgc tcaacaatat gctcaagacg caaactttct ttgtaaataa
    37801 tgtctagaaa gtcatccttg agcgcttctt cttcagctga catcccctta atggtttcag
    37861 caaagccctt aattgaagta actggtgtcc tcaattcatg ggaggcattt gagacaaagg
    37921 ctaaatttaa cttttcataa gttctaatcg ttgttaaatc atatagcaag acgagcacag
    37981 cttccacaga ttgggtgggg ctaaaaacgg gaactgctgt cacttctaaa atcaagtcac
    38041 cctcatgaaa cccacttact tcttgtttta accttgtttt ttgatcaaag gcttggtgaa
    38101 ctaaattccg aatatccatc cgtttgaggt catcaagtga acttatgtcg ccgtccacat
    38161 cgggaaaata atgaggcaga gagcgactgg ataataacat ctgaccttga gcggaaacta
    38221 aaaacgtccc catggttagg tgcgacagaa gaacctccat tgtttcggct aggtccttgt
    38281 attgctgatc ctgttgggag actttggttt ttaggccaga cacatactga gccaaagact
    38341 ttaagtcttc ttgccctttt tctaaaaagt attcactact ggtcaagaga ggttggtgca
    38401 aggtctcaaa agcaacttcc catttccaaa ggcaaaagag ccagtagcca ccttgtccca
    38461 aagaaagggc tagaagaaag agaccgatgc ctttactgat ccaagttaat gccatccctg
    38521 caatcagaat gaggctaaca cttagattga ctagccaaaa ttgaaggtag cgtttcatct
    38581 ataactcctt gaacttataa ccataacccc gaatggttcg aataaattga ggggctttag
    38641 gattgtcttc aattttttcc ctcaacttac caatatgaac gtccaccaaa cgtgtttcct
    38701 gcccaaagtc atacccccag atacgttcca aaagacgctc tctagtcagt gtcatgttgg
    38761 gatgtttcat aagatagagc aagagttcaa attcttttgg ggtcaaactc agtaacttat
    38821 tcgccttgta gacttcatga cgctcagggt atactttcaa ggtcccaaat agccaagaat
    38881 cgtcagcgat attatctgaa tcatctcctt cttgttctcc tttagttcgc ctgaggacag
    38941 ccttgacacg cgccagcaat tctctagggc taaaaggctt ggtcaggtag tcatcagccc
    39001 ctaattccaa ggccaaaacc ttatcaaatt catcactttt cgcagaaacc atcataattg
    39061 gagttttgac gcctttggct ctcagccgct tacaaacttc catgccatct aattgtggta
    39121 acatgatatc aagcaagata aaatcaaagg gttctgtttc tgccaaagct aaggccttcc
    39181 gtccatttgt taccaattga gtagaaaagc cttccttact taaatggtag tcaagcaatt
    39241 tcagaatgtg ttcttcatca tccactaata agacttgttt tgtcatctat tatctcctat
    39301 tggtaacatt ataacacaat tatcagaaat cctaacattg ctaaatcaga ttaaatttgc
    39361 ttatcaagac tagtatctgg tcaaacgctc aatcatctcc ttgtgctctg gataggtcgc
    39421 cagtagatct accctttcaa ataattcaaa atcctcaaat tcaaaaccag gagcaacaag
    39481 acaagaaacc agagcataat ccttatcaac tgttgatccc caaatagtgc ccttaggaac
    39541 acagtagtga agttgttgcc ctttggatat gtccaggcct aaagtgactg cttcgtagtg
    39601 accatctgct gtaatcatgt gaacagtaag tggggatcct gcatgaaaat accagatttc
    39661 atctgctgtc aatcggtgaa aatgtgaagg attcgtttct tctaataaga aataaatact
    39721 ggtataaagc gcccttccct taccagcaag gtttatagtg tctgaagctt tttttgtttg
    39781 tctaaaatag ccaccttcaa catggggagc taactctaga gttcttatca agtcttcttt
    39841 atccatcggg gccaatgggt tgaagtaact cttgttcaaa ggtggtgtta cgatttcaag
    39901 aactcctctc agttctgagg acacggtaat gattgatgcg acggaagtac aaatcaatcg
    39961 ccctaaaaaa agaattagcg aatgattctg gtaaaaagaa atttcacgct atgaaggctc
    40021 aagcgattgt cacaagtcaa gggagaattg tttctattgc catgatatga agttgttcaa
    40081 aatgagttgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg attatcaagg
    40141 gctcatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac tcaagccgct
    40201 aacagctgaa gataaagcct ataaccatgc gctatctaag gaaagaagca aggttgagaa
    40261 catctttgcc aaagtaaaaa cgtttaaaat attttcaaca acctatcgaa atcatcgtaa
    40321 acgcttcgga ttacgaatga atttgattgc tggtattatc aatcatgaac taggattcta
    40381 gttttgcagg aagtctatta tttggttagg tgaattagtg aagtgtttag gcaagtgtct
    40441 ctggttacga cgtcatggcc tctaaatcga ttatatttag gggtcatgac tagtgaagca
    40501 gttagctagt tcgcatataa gcggctagcg tctaacaatt aggaacttta gttccaataa
    40561 ctttaagatt acgacgtttt aggacataaa tcgatcatat ttatgtccta aaactagtga
    40621 agcgcctagc caaagtccga ataggatttg gcgttagtta cttagattgc tttgcaatca
    40681 agtaactttg gcgatttaca tcttctctgg cgcttctact ccaagcaagc gaagggcttc
    40741 tttgagaacg actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt ctgggctttc
    40801 atccaagata cgtgtatgtg catagtattt gttaaaggat tgagccaggc taattgcaaa
    40861 tttagcaatg atagaaggtt caaagttatc tgccgcacgg ttgataatac gtgggaagtc
    40921 ttgaatgagt ttaatgattt cccagctttc agtatcattc aagctatagt tgccagctgt
    40981 ttctggtttg aaatcggctt tgcgtaagat agattggata cgagcgtagg catattgaac
    41041 gtaaggtcca gtttcaccct cgaaggatac catagcttct aggtcgaagt cgtatccatt
    41101 tgtacggtca gttttgaggt catagaattt aatggctcca accccaacag catgtgctac
    41161 ttggtctttg ttttctagtt caggattttt agcctcgatt tggaccttgg cacggctaac
    41221 agcctctgca acagtaggct ctagcaagat gacattccct ttacgagtag agagcttctt
    41281 cccttctttt gtaaccagac caaaaggaac gtgggtaatg tcgtcactcc aatcgtagcc
    41341 catctcttgc aagacagctt tgagttgttt aaagtgggca gattgctctt gaccaacgac
    41401 gtagatagat ttagcaaatt ggtattcatt tttacggtag agggctgcag ccaagtcacg
    41461 tgtgatatag agagttgcac catcagactt cttgatgagg gctggatgtt caattccata
    41521 tttctcaaga ttcacaactt gggcaccttc tgattcaaga agtagtcctt tttcagaaag
    41581 aatgtctaca actgcatcca tcttatcatt gtagaaggct tctccgttat agctgtcaaa
    41641 ttcaaccttc aattcattgt aaaggcggtt aaattccact aaactttcat cgcggaacca
    41701 ttgccaaaga gcgagagctt cctcatctcc attttcaagt ttacggaacc attcgcgcgc
    41761 ttcttcatcc aagctagggt cattttcagc ttcagcgttg atgcggacat agagtttaag
    41821 gagttcatcg attggatgag cttttacagc ttcttcgtcg ccccattttt tgtaggcaac
    41881 aatcaacatc ccaaattgtt taccccagtc tcccaaatgg ttgaccttga ccgtttgata
    41941 accgattttt tggaaaatat gtgacaagct atctccgata acagttgaac gcaggtggcc
    42001 aatagaaaat ggtttagcga tattcggact agacatgtcg ataacaacat tttcttgttt
    42061 gccaatattt tggtcagcat agtgttcttt ttcagtggta acagcttgca atacttgagc
    42121 agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga caactttttc
    42181 aaaggcttgg ctgttcattt tttcagccag ttcagccgca atcatttgtg gtgctttacg
    42241 ttcgactttg gcaagagaaa aagcagggaa agcaatgtct cccatttctg agtttttagg
    42301 ggtttccagt aactttaaaa tagcctcttg gtccaggcta tcaatgatgc tagataattc
    42361 gctagcaatc aattcttttg tattcattaa gagctccttt ttggactttt ctactatttt
    42421 atcacaattt taaagaaaga agaaaaaatt tttgaaatct cctgtttttt tggtataata
    42481 tggttataaa tatagttata aatatgcacg caagaggatt ttatgagaaa aagagatcgt
    42541 catcagttaa taaaaaaaat gattactgag gagaaattaa gtacacaaaa agaaattcaa
    42601 gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg tgatttgcgc
    42661 gaaatcggct tgaccaaggt caagaaaaat gatatggtgt attatgtact agtaaatgag
    42721 acagaaaaga ttgatttggt ggaatttttg tctcatcatt tagaaggtgt tgcaagagca
    42781 gagtttacct tggtgcttca taccaaattg ggagaagcct ctgttttggc aaatattgta
    42841 gatgtaaaca aggatgaatg gattttagga acagttgctg gtgccaatac cttattggtt
    42901 atttgtcgag atcagcacgt tgccaaactc atggaagatc gtttgctaga tttgatgaaa
    42961 gataagtaag gtcttgggag ttgctctcaa gacttatttt tgaaaaggag agacagaaaa
    43021 tggcgataga aaagctatca cccggcatgc aacagtatgt ggatattaaa aagcaatatc
    43081 cagatgcttt tttgctcttt cggatgggtg atttttatga attattttat gaggatgcgg
    43141 tcaatgctgc gcagattctg gaaatttcct taacgagtcg caacaagaat gccgacaatc
    43201 cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat gtcttgattg
    43261 agcagggtta taaggtggct atcgcagagc agatggaaga tcctaaacaa gcagttgggg
    43321 ttgttaaacg agaggttgtt caggtcatta cgccagggac agtggtcgat agcagtaagc
    43381 cggacagtca gaataatttt ttggtttcca tagaccgcga aggcaatcaa tttggcctag
    43441 cttatatgga tttggtgacg ggtgactttt atgtgacagg tcttttggat ttcacgctgg
    43501 tttgtgggga aatccgtaac ctcaaggctc gagaagtggt gttgggttat gacttgtctg
    43561 aggaagaaga acaaatcctc agccgccaga tgaatctggt actctcttat gaaaaagaaa
    43621 gctttgaaga ccttcattta ttggatttgc gattggcaac ggtggagcaa acggcatcta
    43681 gtaagctgct ccagtatgtt catcggactc agatgaggga attgaaccac ctcaaacctg
    43741 ttatccgcta cgaaattaag gatttcttgc agatggatta tgcgaccaag gctagtctgg
    43801 atttggttga gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg cttttggatg
    43861 aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg gattcatcgc cccttgattg
    43921 ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac catttctttg
    43981 agcgtagtga cttgacagac agtctcaagg gtgtttatga cattgagcgc ttggctagtc
    44041 gtgtttcttt tggtaaaacc aatccaaagg atctcttgca gttggcgact accttgtcta
    44101 gtgtgccacg gattcgtgcg attttagaag ggatggagca acctactcta gcctatctca
    44161 tcgcacaact ggatgcaatc cctgagttgg agagtttgat tagcgcagcg attgctcctg
    44221 aagctcctca tgtgattaca gatgggggaa ttatccggac tggatttgat gagactttag
    44281 acaagtatcg ttgcgttctc agagaaggga ctagctggat tgctgagatt gaggctaagg
    44341 agcgagaaaa ctctggtatc agcacgctca agattgacta caataaaaag gatggctact
    44401 attttcatgt gaccaattcg caactgggaa atgtgccagc ccactttttc cgcaaggcga
    44461 cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc ccgtatcgag ggagatatgc
    44521 ttgaggcgcg tgagaagtca gccaacctcg aatacgaaat atttatgcgc attcgtgaag
    44581 aggtcggcaa gtacatccag cgtttacaag ctctagccca aggaattgcg acggttgatg
    44641 tcttacagag tctggcggtt gtggctgaaa cccagcattt gattcgacct gagtttggtg
    44701 acgattcaca aattgatatc cggaaagggc gccatgctgt cgttgaaaag gttatggggg
    44761 ctcagaccta tattccaaat acgattcaga tggcagaaga taccagtatt caactggtta
    44821 cagggccaaa catgagtggg aagtctacct atatgcgtca gttagccatg acggcggtta
    44881 tggcccagct gggttcctat gttcctgctg aaagcgccca tttaccgatt tttgatgcga
    44941 tttttacccg tatcggagca gcagatgact tggtttcggg tcagtcaacc tttatggtgg
    45001 agatgatgga ggccaataat gccatttcgc atgcgaccaa gaactctctc attctctttg
    45061 atgaattggg acgtggaact gcaacttatg acgggatggc tcttgctcag tccatcatcg
    45121 aatatatcca tgagcacatc ggagctaaga ccctctttgc gacccactac catgagttga
    45181 ctagtctgga gtctagttta caacacttgg tcaatgtcca cgtggcaact ttggagcagg
    45241 atgggcaggt caccttcctt cacaagattg aaccgggacc agctgataaa tcctacggta
    45301 tccatgttgc caagattgct ggcttgccag cagacctttt agcaagggcg gataagattt
    45361 tgactcagct agagaatcaa ggaacagaga gtcctcctcc catgagacaa actagtgctg
    45421 tcactgaaca gatttcactc tttgataggg cagaagagca tcctatccta gcagaattag
    45481 ctaaactgga tgtgtataat atgacaccta tgcaggttat gaatgtctta gtagagttaa
    45541 aacagaaact ataaaaccaa gactcactag ttaatctagc tgtatcaagg agacttcttt
    45601 gacaattctc cacttttttg ctagaataac atcacacaaa cagaatgaaa aggagctgac
    45661 gcattgtcgc tcccttttgt ctatttttta aggagaaagt atgctgattc agaaaataaa
    45721 aacctacaag tggcaggccc tggcttcgct cctgatgaca ggcttgatgg ttgctagttc
    45781 acttctgcaa ccgcgttatc tgcaggaagt cttaggcgcc ctccttgctg ggaaatatga
    45841 agctatttat agtatcgggg cttggttgat tggtgtggcc gtagtcggtc tagttgctgg
    45901 tggactcaat gttgtcctcg cagcctatat tgcccaagga gtttcatccg accttcggga
    45961 ggatgccttc cgtaaaattc aaaccttttc ttatgctgat attgaacaat ttaatgcggg
    46021 aaatctagtc gttcgaatga caaatgatat caaccagatt cagaacgttg tcatgatgac
    46081 cttccagatt cttttcagac ttcccctctt gttcatcggt tcgtttatcc tagcggttca
    46141 aaccttacct tctctgtggt gggtgattgt tctcatggta gtcttgattt ttggtttgac
    46201 tgctgtcatg atgggaatga tggggcctcg ttttgccaag tttcaaaccc ttcttgagcg
    46261 catcaatgcc attgccaagg aaaatttacg tggcgttcgt gtggtcaagt cctttgtcca
    46321 agaaaaagag caatttgcta agtttacaga ggtctcagac gagcttcttg gtcaaaacct
    46381 ttacattggt tatgcctttt cagtagtgga accctttatg atgttggttg gttacggggc
    46441 ggtcttcctc tctatttggc tggtcgcggg aatggttcag tcggatccgt ctgttgttgg
    46501 ttccatcgct tcttttgtta attacctaag ccagattatc tttaccattg ttatggttgg
    46561 atttttggga aattctgtca gccgtgccat gatttccatg cgtcgtattc gagaaattct
    46621 tgacgcagag ccagctatga ccttcaagga tatcccagat gaagagttgg ttggaagcct
    46681 tagctttgaa aatgtgacct ttacctatcc aatggacaag gaaccgatgc tgaaagatgt
    46741 gagctttact attgaacctg gtcaaatggt tggtgtagtt ggagcgactg gtgcaggaaa
    46801 gtcaaccttg gctcaattga ttccacgtct ctttgatcca caggaagggg ctatcaaaat
    46861 cggaggtaag gatattcgag aagtgagtga aggaaccctg cgtaaaacag tttccatcgt
    46921 tctccaacgt gccattcttt ttagtggaac gattgcagat aacttgagac aggggaaggg
    46981 aaatgctact ctatttgaaa tggagcgcgc agccaatatt gcccaggcta gtgaattcat
    47041 tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa cggggaacca atttctctgg
    47101 tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc agcaatccac gtattctgat
    47161 ttttgatgat tcgacctcag ccttggatgc caaatcagag cgcttggtgc aagaagcttt
    47221 gaataaggac ttgaagggga cgacaaccat tattattgct caaaaaatta gctcggttgt
    47281 ccatgcagac aagatcttgg ttctaaatca aggacgattg attggtcaag gcacgcatgc
    47341 agacttggtt gccaacaatg ccgtttaccg tgaaatctat gaaacacaga aatgaaagac
    47401 aaactataag aaaagtcaat agttttatct aaactatttc ttatttcaat ttgatgattt
    47461 ggcgatgatt ttagagcacg gcaaaaagct attgaaaaag tccatttttt caaaggtaat
    47521 cctgtgttaa tttcagaaat tacatcactt tttgttcgtc aaatggcagc tcttttttag
    47581 gatataaaac agggttcgga taagtttttt tgcaaggtgg atgatggcta cattgtaatg
    47641 ttttccttgt tctaacttag tcttaagata ggccttaaaa gcaggtgaaa agcgagggca
    47701 tgctttggca gcttgtatga gtacctaccg cagatgaggg gaaccccgtt tgaccattct
    47761 tcctgctaaa tcaatctgac ctgactgata aatagaagaa tccagtccag cgaaagcttg
    47821 taattgagca ggattatcaa aggcatgaat atttcgaatc tcggctaaaa tgaccgcccc
    47881 taaacgattc tcaatcccag taaccgtcgt gatgaccgag ttgaactcag ccatcaagtc
    47941 attgacacat tttttcgcct tgtcaatgag cctcttgtaa tgtttgatgt tttcattaca
    48001 agagataaaa cgtttatgcg ttatcaaact cattaccaat tgaaacaaaa agctgtggtt
    48061 agatcctttc ggaaattgtc aagcgattgg aggaaatgaa ctaatccaca gcggcttatt
    48121 ccaagtatac cacttgggct ttggcagtag ctaactgcgc taaatataat ataaggagga
    48181 gtaaaatgaa gacagttcaa tttttttggc attattttaa ggtctacaag ttctcatttg
    48241 tagttgtcat cctgatgatt gttctggcga cttttgccca agccctcttt ccagtctttt
    48301 ctggacaagc ggtgacgcag ctagccaatt tagttcaagc ttatcaaaat ggcaatccag
    48361 aacttgtatg gcaaagccta tcaggaatca tggtcaatct tggcctgctg gttttggttc
    48421 tatttatctc tagtgtaata tacatgtgtc tcatgacgcg cgtgattgca gaatcgacca
    48481 acgagatgcg caaaggcctc tttggtaagc ttgctcagtt gacggtttct ttctttgacc
    48541 gtcgacaaga tggcgatatc ctgtctcatt ttaccagtga tttggataat atcctccaag
    48601 cctttaacga aagcttgatt caggtcatga gcaatattgt tttatacatt ggtctgattc
    48661 ttgtcatgtt ttcgagaaat gtgacgctgg ctctcatcac cattgccagc accccattgg
    48721 ctttccttat gctgattttc atcgtgaaaa tggcacgtaa atacaccaac ctccagcaga
    48781 aagaggtagg gaagctcaac gcctatatgg atgagagcat ctcaggccaa aaagccgtga
    48841 ttgtgcaagg aattcaagag gatatgatgg caggatttct tgaacaaaat gagcgcgtgc
    48901 gcaaggcaac ctttaaagga agaatgttct caggaattct tttccctgtc atgaatggga
    48961 tgagcctgat taatacagcc atcgtcatct ttgctggttc ggctgtactt ttgaatgata
    49021 agtctattga aacaagtaca gccctaggtt tgattgttat gtttgcacaa ttttcacagc
    49081 agtactacca gcctattatc caagttgcag cgagttgggg aagccttcag ttggccttta
    49141 ctggagctga acgaattcag gaaatgtttg atgcagagga ggaaatccga cctgaaaagg
    49201 ctccaacctt cactaagttg caagaaagtg ttgaaatcag tcatatcgat ttttcatact
    49261 tgcctgataa acctattttg aaagatgtca gcatttctgc ccctaaaggc cagatgacag
    49321 cagttgttgg gcctacaggt tcaggaaaaa cgactattat gaacctcatc aatcgctttt
    49381 atgatgttga tgctggtggt atttattttg atggtaaaga cattcgtggc tatgacttag
    49441 atagtcttag aagcaaggtg ggaattgtat tgcaagattc ggtcttgttt agcggaacga
    49501 ttcgagacaa tatccgattt ggtgtgccag atgctaatca ggaaatggtt gaggtagcag
    49561 caaaagcaac ccacattcac gactatatcg aaagtttgcc tgataagtac gatactctta
    49621 ttgatgatga ccagagcatc ttttcaacag ggcagaagca attgatttca atcgctcgaa
    49681 ccctgatgac agatccagaa gttctcattc tcgatgaagc aacttcaaac gtagatacgg
    49741 tgacggaaag caagattcag catgccatgg aggtggttgt agcaggtaga actagtttcg
    49801 tcattgccca ccgcttgaaa accattctca atgcagatca gattattgtc cttaaagatg
    49861 gagaagtcat tgaacgtggt aaccaccatg aacttttgaa gctaggtggc ttttattcag
    49921 aactctatca caatcaattt gttttcgaat aagaaagaag ttgtcctatg tgggcagctt
    49981 tttcttgtcc ataaaaaatg tttatcacag ccttaaaaaa aacatattag acgaaagtca
    50041 ttttgagtga tatgatagga ctatcgttag tattcgaaag gagaggcatc atggctagaa
    50101 cggttgtagg agttgctgca aatctatgtc ccgtagacgc agaaggcaaa atcattcatt
    50161 catctgtatc ttgtagattc gcagagatca ttcgtcaagt cggtggtctc cctttagtca
    50221 ttcctgttgg tgatgagtca gttgtacgtg attatgtgga aatgattgac aaactcattt
    50281 tgacaggagg ccaaaatgtt catcctcagt tttatggaga gaaaaagacc gtcgaaagcg
    50341 atgattacaa tctggtccgt gacgaatttg aattggcact cttgaaggaa gcgcttcgtc
    50401 agaataaacc aattatggca atctgtcgcg gtgtccaact tgtcaatgtt gcctttggtg
    50461 gaaccctcaa tcaagaaatc gaaggtcact ggcaaggact acctttcggg acatctcact
    50521 ctattgagac agtagaagga agcgtggtgg ctaagctatt tgggaaagaa agtcaggtca
    50581 actcagtcca tcgtcaaagc attaaagatt tggcacctaa tttccgtgta actgctattg
    50641 attcaagaga ccaaactatt gaagcgattg agtctatcga cgagcaccgc attatcggtt
    50701 tacagtggca tccagagttt ctggttaatg aagaagatgg caatttagaa ttatttgagt
    50761 atttattgaa tgaactgtaa cgattggaac atctggtcgt tctttctttt attttttcaa
    50821 aatttttaga atgtggcatt ttacgcaaac gtttgaattc tgataaaaat tggagaaatt
    50881 cgacaaaaaa acttgaaaaa aacgaaggta agcgttatga tagaaaagaa gaaatattgg
    50941 aggaagaaca tgtcacatat taaatttgat tattcaaaag ttttagacaa atttgttgca
    51001 ccacatgaag tggaatacat gcaatcacaa gtaacagcag cagatgaatt gatccgtaaa
    51061 ggaactggtg ctggtagcga cttcttggga tggttggacc ttcctgaaaa atacgaccgc
    51121 gaagaatttg accgcatctt gaaagctgct gagcaaatca agtcagacag cgatgttttg
    51181 gttgtgatcg gtattggtgg atcttacctt ggtgcaaaag cagcaatcga cttcttgaat
    51241 caccattttg ctaacttgca aacaaaagaa gaacgcaaag ctccacaaat cctttacgca
    51301 ggaaactcaa tctcatctac ttaccttgct gacttggtag agtatgttgc agacaaagac
    51361 ttctcagtaa acgtaatttc taaatcaggt acaacaactg aaccagcgat tgctttccgt
    51421 gtctttaaag aactcttggt taagaaatac ggtcaagaag aagctaacaa acgtatctat
    51481 gcaacaactg accgccaaaa gggtgctgtt aaggttgaag cagacgctaa cggttgggga
    51541 acatttgttg ttccagatga tatcggtgga cgcttctcag tattgacagc cgttggtttg
    51601 cttccaatcg cagcatcagg agctgacatc aaagctctta tggaaggtgc gaatgcagct
    51661 cgcaaagact acacttcaga caaaatctct gaaaacgaag cttaccaata cgcagtcgtt
    51721 cgtaacatcc tttatcgtaa aggctatgca actgagatct tggtaaacta tgagccatca
    51781 cttcaatact tctcagaatg gtggaaacaa ttggctggtg aatcagaagg aaaagaccaa
    51841 aaaggtatct acccaacttc agccaacttc tcaactgact tgcactcact tggtcaattt
    51901 atccaagaag gaactcgtat catgtttgaa acagttgtcc gtgttgacaa acctcgtaaa
    51961 aacgtgctta ttcctacttt ggaagaagac cttgacggac ttggttacct tcaaggaaaa
    52021 gacgttgact ttgtaaacaa aaaagcaact gacggtgttc ttcttgccca cacagatggt
    52081 gatgtaccaa acatgtatgt gactcttcca gagcaagacg ctttcactct tggttacact
    52141 atctacttct tcgaattggc aattgccctt tcaggttact tgaatgctat caacccattt
    52201 gaccaaccag gtgttgaagc ttataaacgt aacatgtttg cccttcttgg aaaaccagga
    52261 tttgaagaat tgagcaaaga acttaacgca cgtctataat agaagaaaag agtggtttgc
    52321 ccactctttt tactctcttt atccatagaa attggactca gccaagactt gtgatataat
    52381 atagaaagca aaaaggcaga cgcctagata ataggagaaa ctatgtcaaa agatatccgc
    52441 gtacgttacg caccaagtcc aacaggacta ctacacatcg gaaatgcccg tacagcattg
    52501 tttaactact tgtatgcgcg ccatcatggt ggaacatttc tcatccgtat cgaagatact
    52561 gaccgtaaac gccatgtcga ggatggtgaa cgttcacaac ttgaaaacct tcgctggtta
    52621 ggcatggatt gggatgaaag tccagaatca catgagaatt atcgccagtc tgagcgtttg
    52681 gacttgtatc aaaaatacat tgaccaacta ttagctgaag gaaaagccta taaatcttac
    52741 gttacagaag aagagttggc agctgaacgt gaacgtcaag aagtagctgg cgaaacacca
    52801 cgctacatca atgaatacct tggtatgagt gaagaagaaa aagcggctta tatcgcagaa
    52861 cgtgaagcag ctggtatcat accaacagtt cgtttggctg tcaatgagtc aggtatctac
    52921 aagtggcatg atatggtcaa aggtgatatc gaatttgaag gtggcaatat cggcggtgac
    52981 tgggttatcc aaaagaaaga cggttaccca acttacaact ttgccgttgt tatcgatgac
    53041 cacgatatgc aaatctctca tgttatccgt ggagatgacc atattgctaa tacaccaaaa
    53101 cagcttatgg tctatgaagc tcttggttgg gaagctccag agtttggtca catgaccttg
    53161 attatcaact ctgagactgg taagaagtta tctaaacgtg atactaatac acttcaattt
    53221 atcgaagatt accgaaagaa aggttacctt ccagaagcag tctttaactt tattgctctt
    53281 cttggttgga acccaggtgg tgaagatgag attttctctc gtgaagaact cattaaactt
    53341 tttgatgaaa accgcctcag caagtcacca gcagcctttg atcagaaaaa attagactgg
    53401 atgagcaatg attatatcaa gaatgcagac cttgaaacca tctttgaaat ggcaaaacca
    53461 ttcttagagg aagcaggccg tttgactgac aaggctgaaa aattagttga gctctataaa
    53521 ccacaaatga aatcagtaga tgagattatc ccattgacag atcttttctt ctcagatttc
    53581 ccagaattga cagaagcaga gcgcgaagtc atgacgggtg aaacagttcc aacagttctt
    53641 gaagcattca aagcaaaact tgaagcgatg acagatgatg aatttgtgac agaaaatatc
    53701 ttcccacaaa ttaaagcagt ccaaaaagaa acaggtatta aagggaaaaa tcttttcatg
    53761 cctattcgta tcgcagtttc aggcgaaatg catgggccag aattaccaga tacaattttc
    53821 ttgcttggac gtgaaaaatc aattcagcat atcgaaaaca ttctaaaaga aatctctaaa
    53881 taaagaggat acaataatgg acatctggga aaagatgtac gaagaagcac agaaactata
    53941 caatccacat gaagtatcag actttgttta tgccaatcat gttgtagctg cagtagaagc
    54001 aggagatgga caaatattta caggattctg tatggaggga acctgtggtg ttttccatct
    54061 ctgcgcagaa cgggcgaccc tcttcaatat gtaccaattt tcaggacaaa ctaaggttaa
    54121 gaaagtatta gcctttcgag acaaaccacc ttatggtgga agttcagcca tgccttgcgg
    54181 tgcttgtaga gaattccttt tagagcttaa tgctgaaaat aaagatgcag aattcatgat
    54241 ggactataat ataagaaaaa cagttaaagt cgcagaacta atcccttatt ggtggggaga
    54301 agaacgtgct tctaagttta atgagtgata gaagagtcag tataattctg gctcttttta
    54361 ctataagttg aaaaaataaa aaaaattaga aaaagtagtt gacaaaattt gaaaagactg
    54421 tataatagta agagttgaaa ata
//
LOCUS       DAVEHY010000011        52371 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVEHY010000011 DAVEHY010000000
VERSION     DAVEHY010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52371
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.011"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(75..2033)
                     /gene="ftsH"
                     /locus_tag="VUZ44_000792"
     CDS             complement(75..2033)
                     /gene="ftsH"
                     /locus_tag="VUZ44_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU0319742.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2049..2591)
                     /gene="hpt"
                     /locus_tag="VUZ44_000793"
     CDS             complement(2049..2591)
                     /gene="hpt"
                     /locus_tag="VUZ44_000793"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU0319743.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2595..3872)
                     /gene="tilS"
                     /locus_tag="VUZ44_000794"
     CDS             complement(2595..3872)
                     /gene="tilS"
                     /locus_tag="VUZ44_000794"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU0319744.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKFKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3869..5137)
                     /locus_tag="VUZ44_000795"
     CDS             complement(3869..5137)
                     /locus_tag="VUZ44_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU0319745.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5257..5625)
                     /locus_tag="VUZ44_000796"
     CDS             complement(5257..5625)
                     /locus_tag="VUZ44_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU0319746.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5618..5884)
                     /locus_tag="VUZ44_000797"
     CDS             complement(5618..5884)
                     /locus_tag="VUZ44_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU0319747.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5942..9451)
                     /gene="mfd"
                     /locus_tag="VUZ44_000798"
     CDS             complement(5942..9451)
                     /gene="mfd"
                     /locus_tag="VUZ44_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU0319748.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEKNSI"
     gene            complement(9452..10021)
                     /locus_tag="VUZ44_000799"
     CDS             complement(9452..10021)
                     /locus_tag="VUZ44_000799"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU0319749.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10092..11207)
                     /gene="ychF"
                     /locus_tag="VUZ44_000800"
     CDS             complement(10092..11207)
                     /gene="ychF"
                     /locus_tag="VUZ44_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU0319750.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELNDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPKAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11291..11485)
                     /locus_tag="VUZ44_000801"
     CDS             complement(11291..11485)
                     /locus_tag="VUZ44_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU0319751.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11550..12686)
                     /gene="dnaN"
                     /locus_tag="VUZ44_000802"
     CDS             complement(11550..12686)
                     /gene="dnaN"
                     /locus_tag="VUZ44_000802"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU0319752.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIILTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12845..14206)
                     /gene="dnaA"
                     /locus_tag="VUZ44_000803"
     CDS             complement(12845..14206)
                     /gene="dnaA"
                     /locus_tag="VUZ44_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU0319753.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14419..15177)
                     /locus_tag="VUZ44_000804"
     CDS             complement(14419..15177)
                     /locus_tag="VUZ44_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU0319754.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15235..16416)
                     /locus_tag="VUZ44_000805"
     CDS             complement(15235..16416)
                     /locus_tag="VUZ44_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU0319755.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16599..17078
                     /gene="rlmH"
                     /locus_tag="VUZ44_000806"
     CDS             16599..17078
                     /gene="rlmH"
                     /locus_tag="VUZ44_000806"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU0319756.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17122..17195
                     /locus_tag="VUZ44_000807"
     tRNA            17122..17195
                     /locus_tag="VUZ44_000807"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17156..17158,aa:Arg,seq:tct)
     gene            17360..17485
                     /gene="comC"
                     /locus_tag="VUZ44_000808"
     CDS             17360..17485
                     /gene="comC"
                     /locus_tag="VUZ44_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU0319757.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17506..18831
                     /locus_tag="VUZ44_000809"
     CDS             17506..18831
                     /locus_tag="VUZ44_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU0319758.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18828..19580
                     /locus_tag="VUZ44_000810"
     CDS             18828..19580
                     /locus_tag="VUZ44_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0319759.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19632..19703
                     /locus_tag="VUZ44_000811"
     tRNA            19632..19703
                     /locus_tag="VUZ44_000811"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19665..19667,aa:Glu,seq:ttc)
     gene            19709..19782
                     /locus_tag="VUZ44_000812"
     tRNA            19709..19782
                     /locus_tag="VUZ44_000812"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19743..19745,aa:Asn,seq:gtt)
     gene            complement(19823..20365)
                     /locus_tag="VUZ44_000813"
     CDS             complement(19823..20365)
                     /locus_tag="VUZ44_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU0319760.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20523..21290
                     /locus_tag="VUZ44_000814"
     CDS             20523..21290
                     /locus_tag="VUZ44_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEU0319761.1"
                     /translation="MIGISLIPDLYNIIFLSLMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21375..21650
                     /locus_tag="VUZ44_000815"
     CDS             21375..21650
                     /locus_tag="VUZ44_000815"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319762.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFLQQYQQI"
     gene            21740..22054
                     /locus_tag="VUZ44_000816"
     CDS             21740..22054
                     /locus_tag="VUZ44_000816"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU0319763.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22155..24707)
                     /locus_tag="VUZ44_000817"
     CDS             complement(22155..24707)
                     /locus_tag="VUZ44_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU0319764.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSNLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQILKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24769..26391)
                     /locus_tag="VUZ44_000818"
     CDS             complement(24769..26391)
                     /locus_tag="VUZ44_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU0319765.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26597..27622
                     /gene="trpS"
                     /locus_tag="VUZ44_000819"
     CDS             26597..27622
                     /gene="trpS"
                     /locus_tag="VUZ44_000819"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU0319766.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27774..29252
                     /gene="guaB"
                     /locus_tag="VUZ44_000820"
     CDS             27774..29252
                     /gene="guaB"
                     /locus_tag="VUZ44_000820"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU0319767.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29303..30400)
                     /gene="recF"
                     /locus_tag="VUZ44_000821"
     CDS             complement(29303..30400)
                     /gene="recF"
                     /locus_tag="VUZ44_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU0319768.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30403..30771)
                     /gene="yaaA"
                     /locus_tag="VUZ44_000822"
     CDS             complement(30403..30771)
                     /gene="yaaA"
                     /locus_tag="VUZ44_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU0319769.1"
                     /translation="MEYKLFEEFITLQALFKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQASRFPGR"
     gene            30930..32180
                     /locus_tag="VUZ44_000823"
     CDS             30930..32180
                     /locus_tag="VUZ44_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU0319770.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYCSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32177..33460
                     /locus_tag="VUZ44_000824"
     CDS             32177..33460
                     /locus_tag="VUZ44_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU0319771.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33502..34323
                     /locus_tag="VUZ44_000825"
     CDS             33502..34323
                     /locus_tag="VUZ44_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0319772.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34334..34879
                     /gene="pgsA"
                     /locus_tag="VUZ44_000826"
     CDS             34334..34879
                     /gene="pgsA"
                     /locus_tag="VUZ44_000826"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU0319773.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34876..35703
                     /locus_tag="VUZ44_000827"
     CDS             34876..35703
                     /locus_tag="VUZ44_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU0319774.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35688..36527
                     /locus_tag="VUZ44_000828"
     CDS             35688..36527
                     /locus_tag="VUZ44_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU0319775.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQFLNGLLVPSQGSVRIFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36520..37314
                     /locus_tag="VUZ44_000829"
     CDS             36520..37314
                     /locus_tag="VUZ44_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU0319776.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37373..38191
                     /gene="mreC"
                     /locus_tag="VUZ44_000830"
     CDS             37373..38191
                     /gene="mreC"
                     /locus_tag="VUZ44_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU0319777.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38191..38685
                     /gene="mreD"
                     /locus_tag="VUZ44_000831"
     CDS             38191..38685
                     /gene="mreD"
                     /locus_tag="VUZ44_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU0319778.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38779..39957
                     /locus_tag="VUZ44_000832"
     CDS             38779..39957
                     /locus_tag="VUZ44_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU0319779.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40181..40960
                     /gene="rpsB"
                     /locus_tag="VUZ44_000833"
     CDS             40181..40960
                     /gene="rpsB"
                     /locus_tag="VUZ44_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU0319780.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41039..42079
                     /locus_tag="VUZ44_000834"
     CDS             41039..42079
                     /locus_tag="VUZ44_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU0319781.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42325..42648
                     /gene="tnpB"
                     /locus_tag="VUZ44_000835"
     CDS             42325..42648
                     /gene="tnpB"
                     /locus_tag="VUZ44_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU0319782.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(42789..43076)
                     /locus_tag="VUZ44_000836"
                     /pseudo
     CDS             complement(42789..43076)
                     /locus_tag="VUZ44_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43067..43465
                     /locus_tag="VUZ44_000837"
     CDS             43067..43465
                     /locus_tag="VUZ44_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0319783.1"
                     /translation="MKAPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(43662..44582)
                     /gene="cysK"
                     /locus_tag="VUZ44_000838"
     CDS             complement(43662..44582)
                     /gene="cysK"
                     /locus_tag="VUZ44_000838"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU0319784.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44867..45502)
                     /locus_tag="VUZ44_000839"
     CDS             complement(44867..45502)
                     /locus_tag="VUZ44_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU0319785.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45558..46856
                     /locus_tag="VUZ44_000840"
     CDS             45558..46856
                     /locus_tag="VUZ44_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU0319786.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46853..47515
                     /locus_tag="VUZ44_000841"
     CDS             46853..47515
                     /locus_tag="VUZ44_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU0319787.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47595..48143
                     /gene="raiA"
                     /locus_tag="VUZ44_000842"
     CDS             47595..48143
                     /gene="raiA"
                     /locus_tag="VUZ44_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU0319788.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48279..50252
                     /locus_tag="VUZ44_000843"
     CDS             48279..50252
                     /locus_tag="VUZ44_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU0319789.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50249..50701
                     /gene="rplI"
                     /locus_tag="VUZ44_000844"
     CDS             50249..50701
                     /gene="rplI"
                     /locus_tag="VUZ44_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU0319790.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50745..52097
                     /gene="dnaB"
                     /locus_tag="VUZ44_000845"
     CDS             50745..52097
                     /gene="dnaB"
                     /locus_tag="VUZ44_000845"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU0319791.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52099..52365
                     /locus_tag="VUZ44_000846"
     CDS             52099..52365
                     /locus_tag="VUZ44_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319792.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
BASE COUNT        16389 a         8956 c         9974 g        17052 t
ORIGIN      
        1 gttccatttt ctccattctg ttccctttag ctcctaaact gcacaaaaaa gagaggctcc
       61 agcctctctc agggttattt ttcgtcattc atttttgact ttacttcatc ataggatagt
      121 gcatgagatt cctcttctac tgcttcaggc atctttcctg tttcgtaaag agctttaatt
      181 tgtgtactat ccaatgtttc gtatttcaat aatgcttctg caattaactt gtgagtttca
      241 cgatttgact gaataatttc agcagcttta tttcgtgcct catttaataa tgaacgaacc
      301 tcttcatcaa tttcataagc tgtttgttct gaaattgatt tttgaggact ctgtgcacca
      361 agcatagcat ggtttccttc atattgtact gggccaagtt tttcactcat accgtactct
      421 gtaaccattg cacgtgccat ttgtgtcgct tgttcaaagt cgtttgaagc tcctgtagtt
      481 tggacattaa agataatttc ttcagctaca cgtccaccca ttaagccagc caattgctct
      541 ttcatatctt ctttagatag aagcatttga tcctctttag gaagtgcaat catgtatccg
      601 cctgcacggc cgcgtggtac aattgtaacc ttatggacaa cgcgagcatt cgacaagact
      661 agaccaacaa tggtatgtcc tgcctcatgg taagcaacca attctcgttc tttttgtgaa
      721 actgtcttat ctttcttaga aggtccagca ataactctat cttctgcttc atcaatatct
      781 gaagcatcaa ttatcgattt attgcgacga gcagcaacta aagctgcttc attcaagaca
      841 ttctctaaat cagcaccaac aaagcctgga gtttgttgag ccactaattt caaatcaaca
      901 tcttctgcta aaggcttgtt cttagcgtga actttcaaga ttgcttcacg acctttaaca
      961 tcaggacggc caaccaatac ttttctatca aaacgtcctg gacgcaaaag ggcaggatca
     1021 agtacatctg aacggtttgt cgcagcgatg acgataatcc cttcatttcc ctcaaaacca
     1081 tccatctcaa tcaaaagttg gttcaaggtt tgttcacgtt cgtcattacc tccgccgaga
     1141 ccgactccac gttgacgtcc aacagcatca atttcatcga taaagatgat agctggtgct
     1201 gcttttttgg catcctcaaa aagagagcga acacgactag ctccaactcc gacaaacatt
     1261 tctacaaagt cagaacctga gatactaaag aatggaacac ctgcttctcc agcgactgcc
     1321 ttagcaagca aagtcttacc tgtccccgga ggtccctcca aaagaacacc tgctggaata
     1381 cgggctccaa gttttgtgaa tcgttttgga tcttttaaga actcaacaac ttcaactagt
     1441 tcttgttttt cttcctcagc tccagcaaca tctgaaaatc ttactttaat atcttcttta
     1501 tttgctgctt tagccttact acgtccaaaa ctcattggat tacggccatt gcctcctccc
     1561 atatttccca tcatagagaa taggaagaag aatagaattc caaatggcac aatggatacg
     1621 agtagattaa tccatatacc acttgaactt tcatgcttaa cagttacttc tgctttatgg
     1681 tcagtagcaa gtttttgcaa ttctgatacg gtagtatctg caggaagaat agtgctggta
     1741 aatttctcta ccttagtaac agatggcgtg aaaaactgaa tacctgttcc ttctttactt
     1801 gttttaggat ttttatagac accagaaact tcgataacac taccatttgg ttggtaagtt
     1861 aattctttta cattaccatc ggtaatttct tgtaccaact cagtatagtt gatttgctga
     1921 cttcctcctg agttattccc agaatagaaa tactggaatc ctgtcacaag gaaaaagata
     1981 aataataacc atagaaaagg atttttaatt aaaccattat tttgtttttt cattaaagat
     2041 tattctttct aatttgaata cacttcctct ttcaatactc caatataagg aagattacga
     2101 taattttctt tgtagtctaa accataacct actacaaact catttgggat agtaaagcaa
     2161 gtatagtctg cctcaatttc tacaacacgt ccttctggtt tatccaacaa ggttgcaatt
     2221 ttaacagaag ctgcttctct ttctttaaac atatctcgca aattcttcaa agtttgacct
     2281 gtatcaatga tatcttctac aaatagaaca tgtcttcctt tgatatcttg agtcacatct
     2341 tgtttaatat tgataacacc actacttgct gttccaccat ggtagctaga aaccatcatg
     2401 aagtccattt caatatgtgt atcaatatgt ttgaccaatt cagccataaa aggaatagat
     2461 ccttttaaaa tcccaactaa gattggattt tttcctgcat agtctttagt taattgagca
     2521 cctagttttt tagctgcttc tgtaatttca tcgtgtgaaa cgaggacttt tttaatatcg
     2581 ttttctaaca ttttttacct atctattttt tctatataaa gtacagtgtt cattatatca
     2641 tttttcgttt ttttactcaa attattggtc gcaattccca aaattgagac aatttcacca
     2701 aattgctcaa taataagagc agagtttctc ttttccatag ggattttcaa atcaataaat
     2761 aaacgtctga gtttttttct atgcccattt ttaatcaaaa catctcctgt ttttcgatga
     2821 cgaatgtgta tggatgtttc acgtgaaaca ggtatttgtt gaattaattc accttctaat
     2881 ggaagtccaa aagaaaataa atatccttga taagctacct gattttgata gtgtaacaca
     2941 agttcatctt ccttttcatc agcctgcgga ctgattttac aaatctgaaa ctgttggtac
     3001 tcttttatca attcatagcc atttttaatc ggatgacgat actggctttt aaattttaaa
     3061 atctgctgaa cttcagcaaa ctgagctttt gtaagattca aatctggaaa acgattcaga
     3121 taagtttgaa gtaaaactct ttgtgtagac tcagagtaag aaaataactg ctgtaaatct
     3181 tccacattaa tattgttaga taattcagct attgccaaat cataatctaa aatttcattg
     3241 ccaatgccta agattgcatc cctaaatcga ggattttctt tttccaattc tggtaagtaa
     3301 gaatttcgaa tacgatttcg aaaataatga ttctcctgat ttgatgtatc ttcaaagtga
     3361 aaaattgatg gaaagtcttt tttctgaaaa tgcaagaagg gacgaatgat ttctatctct
     3421 ccgactactt gcttctcctt aattcctgat agatagcgca agcgagttcc tcgaatcaag
     3481 cgcataaaaa tcgtttccac ctgatcatca gcatggtggg cagtgactaa agctgtcgca
     3541 cctgtctttt tcatgacctc ttgaaaaaaa tcataacgaa aatttcgtgc acgcgcttct
     3601 gaaaattctc ctgaaaaatt gctgatataa ataggaagct ctgcttcagc agccaacttc
     3661 cttaattcct tttcttccca atctgattca attctctgct tatgattcac atgagctaga
     3721 atcaattcaa tctctaactc tttttgataa gtagacaata ccttaaatag aaacatagaa
     3781 tctaatccac cagaaagagc tagaaccgcc ttagcatgct ttttgaaata tcccttcttg
     3841 agaaaatgat ttaaaaaatc tggttccctc attttagaac ctcataaaca tccttggcta
     3901 tcttagaaat cgtatcataa tcagaattct tagtgaaaat agaaagaata aatggagaat
     3961 ctgcatagac aacacccgta tcatgcttaa attcatccgc atctccaatt ttatgagcta
     4021 ctttaacaga aacacctttg gcaattcgct gactatcaaa atctgtttta gtcaaagact
     4081 ctagcacaaa tccattttga ttataaatag cttccataaa cttcccggcc atcttagaag
     4141 aaatcaattt ttcttttgga tcccaatcat ctcccataat ggcagacatc ttggatttga
     4201 atgtggcatc agattggttt gaaatgtaat atcccaatag attatgagct acattatcag
     4261 attcttttga tactttcgta attaaatcct ttaaagaata ttctttatta tcttcttttt
     4321 taggaagact accacttccc tctggtttat aagaacctgg aaaatcattg actgcagata
     4381 cgtattttac agtcgtatct aactgataaa gaccctcatt tattttttct tgcgtataat
     4441 agagataaga gagtttcaaa acgctggctg catacatctt ttcatcttga ttgataccag
     4501 cttcttttcc agtagtcagt tgcttaacat aaatagagaa agaatctttc tgatattttt
     4561 cagataacat ttcttgaact ttactcatcc gattatcttc ttcagaagtt gattctttag
     4621 ctacccatcc agcctgatca atatgtagaa attctcttcc ttctacaaac atggtcttgt
     4681 cgattgatac ttgcgaataa gctgataagg atgatttcac ttcttttaaa tcataaggac
     4741 tattgtacag tttaaagtca gattctaacc atactttttt tattgttgga gttacctctg
     4801 attgatcata taaaaatcgt ttgtccgcag ctataaattg atgatttgat agcttaaata
     4861 ctggaattcc ttgtttattt aagcgccact cggttatttg aaaacttgtt ttgggagtca
     4921 atttcccaga ttccactact aaatcttcat tcgcataaac aggaacctct ccataaacca
     4981 tgggagaact taatttttct ctaaaataaa taccaaagtc agattgtgaa aggtaataaa
     5041 tttctttcga agtatagacg acttcttttt ctgtgctaac gacttttgaa atggtcaaaa
     5101 aacttggtag caacaaaata attaagaatt tacgcattct tcctttcctt ttcttcttgt
     5161 aaacgcaata attgattttt atcagccaat tcttccagct tttcatctga caaactcaaa
     5221 aattgctcta ttacgtctaa taaattttcc attttatcac ctttgaagca agtcaggaat
     5281 cgtataaact ttttccctcg acttagaata atagtacttc gctcgtgtat atttagcagc
     5341 ataatcttca tctttcaact tggtagcaaa tgctgtctcc ttatcctttt catcactcaa
     5401 agtttgatac tgagtttgca agtctgctaa ttgctgacgt ctttggagta attgctgata
     5461 actctgcgct aaattaaaag ttggcaagat aaataatagc ataatcaaaa tcaatacccc
     5521 tcccataaaa cgattccgtt tttgtcgttc tttcatcagg tagcgacgac gttggtattc
     5581 attttgaata aaagaattat tcaattgtac aatattttta gacattttct tctacccgtg
     5641 tttcactgat aatttcatac attcctgctg catcttcttt ttttgtacta tctttcatct
     5701 ctagtacttt tacaagcagc aacttattgc caaagcgaat ttcaacttgg tcattaactt
     5761 tcaagtccgt tgaacttttg gccaagattc cattaacctt gattctacct ttatctgcta
     5821 cttcctttgc gactgtacga cgcttgataa ttcgcgatac ttttaaatat ttatctaatc
     5881 tcatccttat tacctcaatt tattattgta ccatttttat ctattttata gaagaaaaat
     5941 atcaaatgga atttttttcc ttagactctt ttatctctaa taaactttct ccaaaaatca
     6001 gcagaccttc taaaatttca taatctttct tattttggac atcaaataca agctccatta
     6061 atcccttatt ctcagcgatg cctgctttta agttcgttac ggataaagct ttaaaataat
     6121 cttgagctaa aaacagtcgt tgagtgactt tttcaaattg aattgtaatt ttattatctt
     6181 ttctttccac acgttgaaca aagaccttgt ccaagtatga tttgaccaaa ccaatctcta
     6241 aaagataggc tactacatct gggtattctc caaaacggtc tatcaactcc tcttgtaact
     6301 cttcataatt gacacggttg tcaatttgac gaattttctt gtaaatttca atcttatgtc
     6361 gttgatcaga aatataagta tcaggaagat aggcatcaat ttgcaaaatc aactcagcat
     6421 tccctttggt tcttgtgtta gcgttagcat taccgtttcg tttagcaata gcttcctcta
     6481 ataactgcga atacaattca aaaccaacag aatcaatgaa accagactgg gattttccta
     6541 aaagatttcc tgctccacga atcgaaagat ctcgcattgc aatcttaaag ccagagccca
     6601 attctgtaaa tcctttaatc gcttctaatc tcttttcaga gacttcactg attgattttt
     6661 ctggacgata catgagataa gcataagcaa tacgattact acgaccgact cttcctctta
     6721 actgatataa ggttgacaag cccatatggt ccgcattttc aataaataaa gtattagcat
     6781 ttggaatgtc cacccctgtc tcaataatag tagtcgtcac caagatatcg tattgtccct
     6841 caataaagtc taatagagta ttttccaact ggacttcact cattcgacca tgaacatatc
     6901 caatcgaagc ctccggaatc aactcctgta attctgaaac cttctgaaca attgtgtcaa
     6961 ctttgttgta aagatagtaa acttgacctc cacgctccat ttcacgcaag acagcatcac
     7021 gaatgacact atcattcttt tccaaaacat aggtctgaac aggatagcga ttagtcggcg
     7081 gagtttcaat aacagacaaa tctctgattc ccagcataga catatggagg gtacgaggga
     7141 ttggcgtagc ggtcaaggtt aggacatcca cttgtttctt cagttctttc aaagtttcct
     7201 tatgcttgac accaaatcgc tgttcctcat caataatcat caagcccaaa tcagcaaaca
     7261 caacatcttt tgacaaaaca cgatgtgttc caatcaaaat atcgacttga ccgtttttca
     7321 atttttcaag tgttgcagtc tgctcttttt tacttctaaa gcgactcaac acatcaacat
     7381 taactgcaaa attttggaat cgttccttaa aattcgtata gtgctgttgc gctaaaaccg
     7441 tcgtcggaac tagaatgaca acctgtttgt gatcattgac tgctttaaag gctgcacgca
     7501 tagcaacttc agtctttcca aaaccaacat ccccaactaa aagtcgatcc attggctgag
     7561 aagcctgcat atccctcttg atttcctcaa tactacgaag ttgatcatcc gtttcaacat
     7621 aagggaaagc atcatcaaag gcatcttgat catcatcatc agctgagaaa gcaaaaccct
     7681 tcaactgact acgttcagag tagagtttga ttaaatcatc agctatatcc tctacctggt
     7741 tcttaacctt ttgcttggcc tttttaaaat gaccgtcatt taatttattg agttttggag
     7801 ctttaccatc acttgaaata tatttggaca gtagatgaat ctgttccacg ggaatagaaa
     7861 tttgatcacc attttggtac tggacactga cataatcgcg atgaattccc ttgatttcaa
     7921 tggtttcaat tcctagatat tgaccaatcc catggatatg atggacaaca tagtcccctt
     7981 tttcaagttc attgtaatct tttaatctct ctgcatttga aacatgttgt cttcgaaaac
     8041 gacgctttaa tttcttttga aaaatctcat gttcagttat caataaaatc ttttcatcta
     8101 caaaatgaaa accatgtctg agattaccct ctattaagtt tacagattct ttacagatac
     8161 ttgtcttatc tctagaatcc aatttaatct gatattcctc taacatatcc tccaatgttt
     8221 tacttcccat tgaattgcta gactgcagaa taatggtgta atccattttt ttatatcgtt
     8281 caatttcttc ttttagaaaa gaaaactgat tgaaaaattc ctgcatagga tattgattga
     8341 attgataaat tttgtcaaat ttgagatttc ctaaaccctt ttgaagatta gagaaaaagg
     8401 tcactggact ttgtttttta tagatttgtt caatatcaga aaaatactgc atatcagaaa
     8461 atgctttact attctgtaat tcttctgtaa agtactgcgc taagtctctt tcaaagactt
     8521 catactgatt catcaatttt tgataatcat caaagaatat tggagtatct ttttcaatat
     8581 aatcaaagac agtccatgtc ttatcatagc acaaagataa aaacttccga gagtctgcat
     8641 gactttgttt ttggtgaaaa cttgaaagaa tttcttctag gtatgatttc aaaataggtg
     8701 ataaagtttt tgaaatttgt ttttctaaag ctgactgtcc tcgttgataa tccttttctc
     8761 tcaaaagcat atcactagct ggaaagatag tgagttctgt cttattttct ttcgataatt
     8821 gtgtttctac ttcaaatgac ctgataccat caatttcatc accaaaaaac tcaattcgac
     8881 aaggttctaa ctgggatatt tcaaaaatat ctaaaatatc tcctcgaaga ctaaattcgc
     8941 cctgagtttg tacttgagta acttttcgat agccattttc ctttaactga tggataaacg
     9001 cgtgttgatc atattcttca ccaactgaga tttttacaat actatctttg aatgcattgg
     9061 gagacggtaa aatcaatcga cttgctacga tattacaaac taaaatccct ttcttagatg
     9121 aatcagtcaa aaaacgcaag gcttcaaccc gtgaaataat tttttcctgt gaagacatca
     9181 aaaactccac cataggagca tcatctacca aaaatggata gacgagttcc tcacccaaga
     9241 tagaaataag atcactaaca agtccttctg cttctccata agttgacgtc aataacacaa
     9301 tcctatcttc tttttctaaa ctgcttgcaa ttgcaagagc cttagtagat gttgataaac
     9361 caagtattag ttgtcttttc ttatctgtta aattttgatg ccatttttta atctgatcat
     9421 tttctgagaa taaatctaat aaggtcacca tttatccgtt atacctctgc attgttttct
     9481 caaaattttt ctcttgtaaa tagtagttta cagaatcgtc aactttgtca acagactgta
     9541 aaataccgat ataatcatcc ctgtcaaact tactcaaaac atgatgaaca actgacatac
     9601 catttttagg tcttccaatt ccaatcttaa cacggttaaa gacctgagtt cctatatgtt
     9661 gaataataga cttgatacca ttatgaccac ctgctgagcc ttttgctctt aaacgaattt
     9721 tcccaacttc catgtcaaga tcatcgtaaa tgataagtaa atcgtcaata tccaaaccat
     9781 agtaagttaa taaagcatga actgcttttc cactttcatt cataaaggtc gttggtttaa
     9841 ccagataaat tttttctcca tttaggaaaa aggatgctag gtcagcttga aatatcttat
     9901 cgtgtgtaaa agtgacattc tgtttcttcg ctagttgatc aatcaacatg aaaccaacat
     9961 tgtgttttgt ttcaaaatat ttatcccctg gatttcccaa gcctacaagt aatttggtca
    10021 tttatttttc ctttcaaaag ccaaaagggt tggaattttt ttccaaccta attaacacca
    10081 tttattaatt tttagacatt aaagcggaat tccatgatat cgccatcttg aacgatatat
    10141 tcttttcctt cttcacgcaa gcgtccagct tcttttacgg ccttttcaga tccgtatttc
    10201 actagatctt catatgacat ggttactgca cgaataaagc ctttttcaaa gtctgaatgg
    10261 ataataccag ctgctttagg agccttcata ccacgtttga aagtccaagc gcgaacttct
    10321 ttttcaccag ctgtgaagta agttcccaat ccaagcaagt ggtaagctgc acgcgtcaac
    10381 ttatctacac ctgattctgt caaaccaatg gcttcaagaa actctttttt atcttcatca
    10441 ttcaattcag aaatttcttc ctcagcacgc gcagaaataa cgactacttc agcattttct
    10501 gtcgctgcaa attcacgaat ttgtttgaca tagtcgatag agtcaggttc tgaaaccaca
    10561 tcctcgtcca cattagctac ataaagaact ggtttagtcg tcaaaaggaa aagacctttg
    10621 acaacctttt gttcctcatc tgtaaattca atggtacgag ctgatttccc gtcttctagg
    10681 actggtttaa tcttttgaag aacattgaat tctgctactg attctttatc tttttgcgta
    10741 cgtgccatct tttctacacg cgcatatcgt ttgttcactg attctaagtc agcaagaatc
    10801 aattccagat taatggtatc aatatctgca agtggatcta caaaggcgtc ttcacgtcct
    10861 tgctcgcgca ttacattttc atcatcaaaa gcacgaacta cgtgaacaat cgcatctact
    10921 tcacgaatat tggccaagaa tttattccct agcccctctc cttttgaagc tccttttaca
    10981 atccctgcaa tatctgtaaa ttcaaatgtt gtgggaactg tctttttagg agttatcatt
    11041 tcagttagtt tttgtaggcg ttcatctgga acttccacca ttccaacatt tggatcaatc
    11101 gtcgcaaatg ggtagtttgc tgcctctgct cctgcttttg taattgcatt aaatagtgtt
    11161 gatttaccaa cgtttggcaa accaacgata cctgctgtca aagccatatt tctcattctc
    11221 cgttttcatt tcaatcccta atattataac acaaaaaggg ataaagtgct aaccctctaa
    11281 ctaagggttc tcagtcaata attttattca tttttcgctc aaaatcatat cgccccatca
    11341 tgacaacatg ctcacaatta ctacatttta ttttgatatc tgctcctaca cgtgtaattt
    11401 cccaacgatt agccttttta ccagtcgact tgattgtaca agcgtgtgat tttttcatct
    11461 caacaaaatt tccaacttga tacatactac tctccttttc tttttcgatt atatcataaa
    11521 agaggcgagc caggctcaac ctctttcact taatttgtac gaactggtgt aatgagctgc
    11581 atgaagtctt cgtcagtatc tgctggcaca agagtaaatg gacgaacagc tgagataaag
    11641 ctaatagtca ccttttcgct atttaaagct ttaagagaat caatcaagta agttgggttg
    11701 aaactaatgg tcaaatcttc accagtaacc tgatcagtat cgatttcttc gtttacttta
    11761 ccaacttctg gagagtgaac atgggcgcta acaaccccat ccttaatttc aagtttcaca
    11821 gtaccatttt gagtcgcact tgataaaaga cgggcacgct ccattgactg gcgtaagttt
    11881 accacattaa aagtaatagt agtgttaaag tctgttggaa tcaagcgatc tgtatcagga
    11941 tagtttcctt ctaggagacg agtatagaag ctaatatttt cgcttctaaa gaggatttgg
    12001 ttattggcaa agaaaatctc tacagtttcg atatcatctg taaataccgc tgaaaattcg
    12061 cgtagagaac ggctaggaat tacgacatca aaatcatcac tatttttttc aagagtcaat
    12121 tttttctggc ttaggcgatg agagtctgtt gcaactgttt ttaactcttt gtgttgactc
    12181 aatacgaagt ggacacctgt taaaatcgga cgactctctt gtgtacttgc agcaaaggct
    12241 gtttcattaa taattttctt gagtaatttt gtttcaagta ttaaaggagt gcttgctgaa
    12301 atttcttgga ttcgtggata ttgttcgcta tcttttcctt ttagggtaat ttctgatttg
    12361 ccactggtta aaataatttg attttgttca atttctttaa aatcaagagt tacatcaggt
    12421 aaactagata ctacattgat aaagaaagaa gcttcaagaa ggatcgaacc taaagaagta
    12481 attaacaaac cagcatcttc atttttttga gaaataaaat tttcaattga aatttgacca
    12541 tttgaaccaa ttaaagtaat accttcattg gtcacgtcaa tttttactgt tgataaaata
    12601 ggaatggcat ttttagaact aatagctctc ttagtagtat ttaatgcttg tagaaataaa
    12661 tttttattaa ttgaaaaatg aatcatggat tctcctttat ttatttttag tattagaaag
    12721 ataatagtaa taatagagtc tgtgaaatct gtggaaaaca gcctttaaac aagtcatatc
    12781 aagtttttta gcttgtttaa aaaatgtgga taaaaaagat aaaaaactaa aagttatcca
    12841 caaattattt gattttcttt ttgattgatt caatttctaa acgtaaatta tcgtcttgat
    12901 caatcaaaga ttttattttg gcatgggcat gaatgactgt ggtatgatct tttcccccaa
    12961 attccttccc aatttttgga agactattat ctgttagttc tctagataaa tacatggcta
    13021 cttgacgggc caaaacaata ttttgaaggc gtctacttcc cttcatttct ttgatactaa
    13081 caccataaaa gttaccaact tcagtttgga ttttatcaat tgggatgacg agcatttggc
    13141 taacatcttg tttgcgggct ctaatggctt ctgcagcaat atcaatagtg atatccttga
    13201 ttttttttac tctggcaatt aaagtgatgt cgttgatggc tccctcaaga tctcgaacat
    13261 ttgaatcaaa ttgcccagct aggtattcta gagtatcact ttggaaattg tagcctaaat
    13321 gttccgtctt actttgtaaa atggcaatac gtgtttcaaa gtcagggggt gtgatagttt
    13381 gtgtcaatcc ccaactaaaa cgcgtgacaa gcctctcctc gagcccttct agatgttttg
    13441 gactacgatc actcgttagg acaatctgtt tttgcttgtc atgaagggcg ttaaaggtat
    13501 tgaaaaattc ttcctgagtt gcgacttttt ttccgctgag tgactgtata tcatcgatta
    13561 acaaaagatc aagactacga taggtctttt taaacttttc catttcccca agtcttaggt
    13621 gatcaagaaa gtcattaata aagctttcgg cagggatata tttaacacgc gcattaggaa
    13681 tattttttag aatttcattt ccaatagcgt ttaataagtg agtcttacca aggcctggtc
    13741 ctccatagat aaaaagaggg ttataggtca gagccaaatc ttcagagaca gctaaagcgg
    13801 ctgatacagc ccaaacattt ccatcccctt gaataaagtt atcaaaggta tacttttctt
    13861 ttaatcccgt atctgaataa ggaatagata ctaactttgg actatagtca taaagagtta
    13921 aatttgtagc ttcttcaact tgtgagctag tcgtatcttg aggtttggtg aaaatatagt
    13981 ggggagttat ttcagcgtca taaatttcaa aaccagctac tacaataata tcttttagtt
    14041 gtttttccca gaccatttcc atttcagagc gaggtagaaa tatagtggca acattttcct
    14101 ctaccttgat gagttcagct tgaatagcat agaaatcata catggatcga gtcagtcttt
    14161 cttgtgcaaa ttctaatata cgattccaaa attgtttttc tttcaatcct ttctcctcct
    14221 ttactattta aaagtttaat actagagata ttttaccata gatagcaaga attttccaca
    14281 agctgtgaaa aataatccac aatgttacca aactttatcc acaggttggg gataaaagaa
    14341 gaaattattg atttattaag ctttttatcg aaaaacatag tggataacct tgtgagataa
    14401 aaaaataaaa gaacagcctt atttcaggct gttgataatt ctactatatt cttcttgatt
    14461 tgaaaaagaa ataatgattt ttccactgtc ttttttagat agtttaattt ctacatctaa
    14521 tccgagtagt tttcttaact gtttttcttc attttgtatg aaatgattag ttttttgctg
    14581 tttcttttgt tttttctctg tcagaagagc ttctaatttc cttacagaaa tatcttcttc
    14641 tataatccgt tgaaagaaat agtcttgttg ttccttattt aacccaacta gggaacgcgc
    14701 atgggcttgt gatagtttgc cattttctac ttctgaaaga atctgttctg gcaaggaaag
    14761 taaacgaatg gagttgctga tatatggacg agacttgccc atcttatctg caatttcagc
    14821 atgggtgaat cctttctcta cgagagattc ataggcgcgt gcttcttcta ttgggtttaa
    14881 attttctctc tgtaaatttt caataatgga ctggaccatc atctcttggt ctgaaatctg
    14941 tttaacaaca gctgggatag accgtagacc agctaaaagt gaagcccgat agcgtctctc
    15001 tcctgcaagg atttcataac caataacagg agattgacga acaataatcg gttgaatgac
    15061 cccattttct ttgatagact gtgctagttc atctagtttt tctctatcaa attcttttcg
    15121 gggttgatag ggattttttt gtatatctgt gatagaaatc atttcaaatt tttccatgat
    15181 tctacactaa cacatctttt ctcttatgta aagctttctt tacatagatg tcaatcaaga
    15241 ttctaaatca cctgaactct tgttaagttt gatagaggta gtttcttctt tcccgttacg
    15301 atagtaggtt atcttaatgg tgtctccgat agaatggttg taaagagcac tttgtaagtc
    15361 tgttgatgaa gcaatctctt tgtcatctac ttttgtaatt acatcgtatt tttcaaggtg
    15421 accattggca ggcatattac tttgtaccga acgaacaact acaccagatg taacattact
    15481 tggaatattg agtcttctga tgtcgcttgt actcacatta gataaattaa ccatctggat
    15541 tcccaaagct ggacgcgtca cttttccgtt tttttctaac tgttcaataa tattaatagc
    15601 atcatttgca ggaattgcga aaccaagacc ttctacagat gttcctccat ttgtagcaat
    15661 tttacttgag gtaattccga taacctgccc ttgaatattg atcagtgggc cgccagagtt
    15721 acctgggtta atagcagtat cagtttggat ggcttttgta gaaatagctt gtccatcttc
    15781 cgatcttaag gatacatttc tattgagact ggatacgata ccttgagtga cagtatttgc
    15841 atattcagaa cctaacgggc taccgatggc aatagcagtt tctcctacag ttaacttact
    15901 agaatcacca aactcagcta ctgttgtcac tttttctgaa gagattttga cgacagcaat
    15961 atcagagaaa gtgtcagctc cgacaatttc tccaggtact ttagtcccat ctgacaatct
    16021 aatatctact ttgctggcgc catttataac gtgattgttg gtgacgatgt aagcttcttt
    16081 atcattcttt ttataaataa ctccagatcc ttcactagag attcgctgag aatctgtgtc
    16141 agtatcatca ttgccaaata cgctattttg tctgtttgcc gaataagtaa taacagaaac
    16201 aacagcatct tttactttgt taacagcctg tgttgttgaa ttttcgttct tataggcagt
    16261 ttgtgtaata gtactattgt tgttagagtt gtttacacta cttttttgag ttagttgagt
    16321 tattgaaaaa ctacccaagg ctccactaaa aaagctaatg acgataacga ctaataattg
    16381 aaaccatttt ttgtaaaatg tttttagatg tttcatattt gcctccatat gtttgaatta
    16441 ctgaaagtat aaactgacta gcttaattat aacttaaaca caaaagtttt acacaaactg
    16501 tggataactc ttttgaaact gtgattttct taattgaaat ctatttttta ttttgtgaat
    16561 aagatgtgaa aaaatagaga atatgttaga atagagtcat gaaaattaaa gttgtaacag
    16621 ttgggaaact gaaagaaaag tatttaaaag atggtatcgc agagtattca aaacgaattt
    16681 ctagatttgc taagtttgaa atgattgagt tatcagatga aaaaacacca gataaggcca
    16741 gtgaatcaga aaatcaaaag attttagaaa tagaaggtca gagaatttta tcaaaaattg
    16801 ctgaccgtga tttcgttatt gtgttagcca ttgaagggaa aactttcttc tcagaagaat
    16861 ttagtaagca gttagaagaa acttctataa aaggattttc tactcttact tttattattg
    16921 ggggaagttt aggattgtca tcatctgtaa aaaatagagc caatctttct gtcagttttg
    16981 gtcgcctaac cttaccccat cagttaatga gactagttct tgttgaacaa atctatcgcg
    17041 cttttacgat tcagcaggga ttcccctacc ataaatagaa aattgacttt taattgaatt
    17101 tttggtagaa taattgtatt aggtctcata gctcagctgg atagagcatt cgccttctaa
    17161 gcgaacggtc gcaggttcga atcctgctgg gatcaatata atagcaaagc tgggaatttt
    17221 cccggctttt ttcttaaaaa agtacacttt gggagaaaaa aatgacagtt gagagaattt
    17281 tatctaaaac gaaattccat tttgtataat ggtttttgta agttagctta caagaaaaaa
    17341 cattttagga gattttatta tgaaaaacac agttaaattg gaacagtttg tagctttgaa
    17401 ggaaaaagac ttacaaaaga ttaaaggtgg ggagatgagg ttgtcaaaat tcttccgtga
    17461 ttttatttta caaagaaaaa agtaatgaaa taaggggaaa gagtaatgga tttatttgga
    17521 tttgggacgg ttattgttca ttttttaatt attagtcaca gttaccattt tatttgtaaa
    17581 ggtcaaataa atagaaaaga attattcgtt tttggtgctt atacattact aacagaaata
    17641 gtatttgatt ttcccttata tattctatat ttagatgggt tagggattga aagattttta
    17701 tttcctttgg gattatattc ctattttcga tggatgaaac agtatgagag ggatagagga
    17761 ctattcctaa gtttactact atctctttta tatgagagca ctcataactt tctgtccgta
    17821 actttctcct ctataacagg agataatttt gttttacaat atcatttccc attctttttc
    17881 gttgtgacgg tgttaaccta ttttgttaca ttaaaaatca tttactattt ccatttggaa
    17941 ctagcctatt ttgacgagga ctacctttat cctttcttga aaaaagtatt ttttgcttta
    18001 ctattgctac atattgtatc tttcgtttca gatatggtaa gtacgattaa acatttgaat
    18061 agttttggaa gtattttgtc atctattgtc tttatctctc tccttttgac cttctttgca
    18121 atgaattctc ataaagttca aatggagaaa gagattgctt tgaagcagaa gaaatttgaa
    18181 cagaaacatt tacagaatta cacagatgaa attgttggtc tgtataatga aatccgtggt
    18241 tttcgacatg attatgctgg aatgcttgtc agcatgcaga tggcaattga cagtggtaat
    18301 ttacaggaaa ttgacagaat ttacaatgaa gttttagtca aagcaaatca taaattgcgt
    18361 tcagataagt acacttactt tgatttgaac aacatagaag actcagcttt acgaagtttg
    18421 gttgctcagt caattgtcta tgctcgaaat aatggtgtag agtttacact ggaagtaaaa
    18481 gatacgatta ccaagcttcc aattgaacta ttggatttgg ttcgtatcat gagcgtttta
    18541 ttgaataatg ctgtcgaagg atcggctgat agctataaaa agcagatgga agtagcagtt
    18601 attaagatgg aaactgaaac agttattgtg attcagaatt catgtaaaat gacgatgact
    18661 ccttcaggag atctatttgc cttaggattc tccactaagg gaagaaatcg cggagtcgga
    18721 ttaaataatg tgaaagaact actagataag tacaacaata ttattttaga aacagagatg
    18781 gaaggcagta catttagaca aatcattaga tttaagaggg aatttgaatg aaagttttaa
    18841 ttttagaaga tgttattgaa catcaagtga gactagagag aatattggat gaaatttcga
    18901 aagaatcgaa tattccaata tcatacaaga caacgggaaa agtccgtgaa tttgaagaat
    18961 acattgaaaa tgatgaagta aatcagcttt atttcctaga tatcgatatt catggaattg
    19021 agaaaaaggg atttgaagtg gctcagctca ttcgtcatta caatccttac gctattatcg
    19081 tctttatcac tagtcgatca gagtttgcga ctctaaccta taaatatcag gtatcagccc
    19141 tagattttgt tgataaggat atcaatgatg agatgtttaa gaagagaatt gagcaaaata
    19201 tcttctacac gaagagtatg ttacttgaaa atgaagatgt tgtagattat ttcgactaca
    19261 attacaaggg aaatgattta aaaattcctt accatgatat tttgtatatt gaaacaacag
    19321 gggtatctca taaattgcgc attattggta agaattttgc aaaagagttt tatggtacca
    19381 tgacagatat tcaggaaaag gacaaacata ctcagcgatt ttattctcct cacaagtcat
    19441 ttttggtaaa tataggcaat atcagagaaa ttgatcgaaa aaacttagaa attgttttct
    19501 atgaagacca tcgttgtcct atttcaagat taaaaattag aaaattaaaa gatattttag
    19561 agaaaaaatc tcaaaagtga ttgacaatta gcaagaaatt gatataatgg ttatatctgc
    19621 tacagataga aggtccgttg gtcaaggggt taagacaccg ccttttcacg gcggtaacac
    19681 gggttcgaat cccgtacgga ctattttatc cgccatagct cagttggtag tagcgcatga
    19741 ctgttaatca tgatgtcgta ggttcgagtc ctactggcgg agtatagata aaagggaaca
    19801 cagctgtgtt cctctttttg tatcaatttg tatcaccaag cattttcata aggaagtctg
    19861 ttatttcttg agaactttct ttttttccat gtgcaatcca agtttggcag acaccaaaaa
    19921 gtgcatgagt tagatagatg ctactatatt ctaattcggt ggtatttaga ttcagttgca
    19981 taaatcgctt ttgtaaatct gtactaagca tgatatgaag tttatttcgt aagaaatttt
    20041 ggatttcttt agtcccattt tcagaaagaa gggcagccag aagtggttct gactctagat
    20101 attcaaaaac ttctaaaata gcgtctcttt tgtgatgagc atgtttttga aaaatatatt
    20161 caaatgtatg gaatagcttg ctttgatagt gctcaatcat atcatactta tccttatagt
    20221 gagtatagaa gctggaacga ctaattccgg ctttttctac taatttgaca gtagaaattt
    20281 tatcaaatgg ctgttccatc agtaattgta ccatagcatt ttcaatagtt cgctttgttt
    20341 ttaagcgttt gttactttct tgcatatttc ctccttgtaa acaaattaga ctatatgtct
    20401 aaaaatagat tttttaatgt ataatctatt atatcaaaat tttagacaat atgtttaaaa
    20461 aaggagaaac taagtttaaa gaatggaaag caatttaaaa aaaaccaacc tttattattg
    20521 tcatgatcgg gatttctctt attccagatc tgtacaatat catatttttg tcattaatgt
    20581 gggatccata tgggcaattg tctgacttac ctgtggcagt tgtaaataat gataaagagg
    20641 cttcctataa tggtaatact atggcaatag gaaaagacat ggtgtccaat ttaaaagaaa
    20701 ataaaacctt ggattttcat tttgtagatg aagaggaagg aaagaaggga ttggaagatg
    20761 gcgattacta tatggtagtg actttaccaa gtgatttatc tgaaaaaaca actacattat
    20821 ccaatattca atcgacagca gcttatcaat cattgacaag tgagcaacaa actgagataa
    20881 gtgattctgt atctcaaaat tcaactgata gtattcaatc ggctcagtca attgtagctt
    20941 tagtacaaga tttacaggga agtttagaaa acttacaaaa tcaatcttct aatctttcga
    21001 ctttaaaaaa tcaatctaat caagtatcac ctattacttc tacttctttg ataggattgt
    21061 caagtggatt aacagagata caaggagatg ttactagcaa attagttcct gccagtcagt
    21121 cgattgcatc aggtgtaaac gcatatacta caggtgttga taaagtttct cagggcgcaa
    21181 gtcaactaag tgaaaaaaat gccaccttga caggtagttt ggataaacta gtttcaggct
    21241 caaacacctt gacacaaaaa tcttctagat tgacagcagg agttggttaa ttacaatcag
    21301 gatctgggca attagcagac aaatccagtc agttactttc aggtgcttct ccattagaga
    21361 atagagctaa taaattggca gatggatctg ggaaactagc agaaggtgga acaaagttaa
    21421 cttctggatt ggaagattta cagacaggac ttgcttcttt aggacaagga ctaggtaatg
    21481 ctagtgatca actcaaatca gtatcaacag aatctaaaaa tgcagagatt ttgtcaaatc
    21541 cactcaatct ttcaaaaaca gacaatgatc aagttcctgt aaatggaatc gcaatagctc
    21601 cttatatgat atcagttgct ctttttttgc agcaatatca acaaatatga tatttgcgaa
    21661 attgccttca ggacgtcatc cagagagccg ttgggcttgg ttgaaatctt gagctgaaat
    21721 aaatggtatt atagctgttt tggcaggaat tttggtatat ggaggagttc agcttattgg
    21781 tttaactgct aatcatgaga tgagaatatt tattctcatc atcctaacaa gtttagtatt
    21841 catgtctatg gtgaccactt tagcaacgtg gaatagccgt ataggagctt ttttctcact
    21901 tattttgctt ttactacagt tagcatcaag tgcaggtact tatccacttg ctttgacaaa
    21961 tgatttcttt agatctatta atccctggtt accaatgagc tattcagttt cgggattacg
    22021 acaaacaatc tctatcaaca agtcattttc ctagctgtca tactagttct atttactagt
    22081 ttaggtatgc tagcctatca acataagaaa atggaagaag attaaaaaaa tcgaccgatt
    22141 aactggtcga ttttttatgc cttagatgac tttcgtctgt gattatagat tccaaatagt
    22201 aagagagaag taaaggaaca gattgctcca gtaataaaac cattgggaat gaaggaaagt
    22261 gtaatagttc ctttcccctt gggaatgtca actttcataa atccagtttg agcttgttta
    22321 atttctattt tcttaccatc ttggtaggca gaccaacctt tgtcataagg aatggtgaag
    22381 aaaatagatg tatcttgttg gacatcatat gtagcaaaaa ccttgttttt agaagttgat
    22441 actgtgacag gttgttcttt aattttttga attgcctcgg tgaaagtttt ggtatctaaa
    22501 cgatagaagg taggagattc aaatgatact tgtgaatttc cagggaaact aacattgata
    22561 ttgaaagttt ttttctcttt agtatatcct agattaaaga aggagaagac attatcagtt
    22621 gtaaaagtct ttttttcacc atttacaagg atgtcaacct tcttttgttt atcgttagaa
    22681 aagtgaaggt ttatgaaaga gagataaact tggctgtttt ctggaacttc aatttgatac
    22741 tggattgctg catcttcatt tgaagaactt gtgacactaa tcaaatcatt agtattttct
    22801 attttttctg ttttttcata aggtattgga gaaaaataat caaaattgac gttagcaagt
    22861 tgatttaaaa atgaggcctg attatccaag gtatgttcat tgaacttgac atcattgtaa
    22921 acagattgac tcgcaactgc aatcggaaga gagtattgat tttcatatag ggtaagatta
    22981 tctttttgat agatatcttt aaagccatac ttatcaatag gactgtctga gatattgtac
    23041 tggataccaa ataaactatc agccaaaata ctattatttg catatcggag attgagatta
    23101 gtcccagagg atttaaaacc aagtttatct aaagtagagc ttgatgaacg atttcgaaca
    23161 gatgaaaatt gagagattcc attgtagttg aatttcatac tgtcatttcc tgtctgagtt
    23221 tgtagttttt cagtacgagt aaattgattt ccaatatatg ttgagaaaga ttccatagct
    23281 gggatatctc gactataagc acttcgagaa gcaaatcccc attccttagc aattccgtcc
    23341 atttgagatg aagcatttaa actcatttca accagtataa ataaagagat tagaatggca
    23401 aatagattca cagatataaa ctttttgata actgcaagga gtaaaagaga atagacaacc
    23461 aaaaattcaa gagtaagcag aatattcaaa tctgttaaaa aagaataatg cgattttaga
    23521 tagatggtag ctaaaaatcc tgctactaca agaaaaagcg aaactaaaaa attccagact
    23581 ttaagttctt tcagacgctt taagacttct gctgctgtgt aaattaacaa ggtagagaaa
    23641 atccaagcat agcgatgtaa aaacatgttt ggagtatgca tgccttgcca aaataagtca
    23701 agagcttcta tgtaaaagct tgcaattaga aatgcaaaga atattacata tatgagtttc
    23761 acgtgaaact taatagattt cagcgtaaaa aataaaatgg tcaaaataaa gggaaatagt
    23821 ccaacaaaaa tcattgggat ggccccatac tttgttgtgt caaaggaacc aatgaattgc
    23881 ttagcaaaga gatcaagata ccagctactt tcagtttgaa actttgtaac ttcagtcaat
    23941 ttttccccat gtgtctgtaa atcaaataga gtgggaagag tcataatcaa actagccata
    24001 ccagctaaaa aggagataac tatgaaatca agaacagatg attttcgagt cttaaagtcc
    24061 cacgaaattt gacagagata ccagaaaata agaaacaata ctgtcatata tccaaaataa
    24121 taattttgaa taaataagat tgacagactt gtaaagtaca ataggagttt cttttcagtt
    24181 atcagtagat gtaaaccagt tataattaaa ggaatcaaga taaaaacatc tagccaggtt
    24241 tttatctcta attgactgac agtgaaactc atcagagcat aggaagtaga taaggctagt
    24301 tttaaaatct gagggataga ttgaaacaat ttattcaaac taaaaaaggt tgacagacca
    24361 atcaatccaa attttaagag agttgtcaga tagatagcat ctggcatatt cgttagatca
    24421 aaaaagtaaa ccagaggcgc gagaaaacta cccaagtaat aactagatag ggcatagaag
    24481 tttagcccta gaccacttgt aaaggtgtaa aacagattac tatttccatg taggatattt
    24541 cgtaaggcta catcaaaaat aacgtattga tgaaagccat ctcctaatag aggagagttg
    24601 tcgctattcc agtagatacc ttgagataga tatactccag acataatcac tacaggaatg
    24661 atgaaagaaa taaaataggt tcgatatgtt tttaaaaatg atttcatgtt acctcgtaga
    24721 atgatagaaa actcagttgg ttaacccaac tgagttttga agttttattt agtctttcca
    24781 aagttcttta acttttgctt gtacttctgc attttctagg aattcatcgt aggtttcatc
    24841 gatacggtca atgacgccat ttttagataa gacaatgata tggttagcca aagtttgaat
    24901 aaattcgtgg tcatggctgg caaagatgat tgattcttta aagtttttca atccatcatt
    24961 caagcttgag atagattcca agtccaagtg atttgttgga tcatcaagta caaggacatt
    25021 tgattttaag agcatgagtt ttgaaagcat gacacgaact ttttctcccc ctgacaagac
    25081 atttacaggt ttgttaactt catctccaga gaagagcata cggccgagga agccacgtag
    25141 gaaagtattg tcatcttctt ctttacttgc gaattgacgc aaccagtcaa gaattgattc
    25201 tcctcctgca aaatcagctg agttatcttt tggtaggtaa gattgactag ttgtaactcc
    25261 ccacttgaca gttccttcat agtcaatatc tcccatgatt gcacgaatta atgcagtcgt
    25321 ttgaatatca ttttgtccaa taagtgctgt cttatcatct ggacgcaaga tgaaactaat
    25381 attatccaag atagtttcac catcaatctt tacagttaaa ttttctactg tcaagagatc
    25441 attaccaatc tcacgttccg ctttaaagtt gataaatgga tatttacgac tagatggcac
    25501 aatctcttct agctcaatct tatcaagcat tttcttacgt gatgttgcct gccttgactt
    25561 agaagcattg gcagagaaac gagcaacaaa ttcttgcaat tgtttaattt tttcttctgc
    25621 tttagcatta cggtctgcta gcaatttagc agcaagctca gaagattcct tccagaagtc
    25681 gtagtttccg acatagagtt tgatttttcc aaagtcaagg tcggccatgt gagtacaaac
    25741 tttgtttaag aagtgacggt cgtgggatac tacgataact gtgttatcaa agtcaatcaa
    25801 gaagtcttct aaccaagtaa tcgattggat atccaaaccg ttagtaggct cgtccaagag
    25861 aagaacatct ggtttaccaa aaagtgcttt ggcgaggaga acctttactt tttcaccgtt
    25921 ggccaattcg ctcatgtttt ggtagtgtaa ttcttctgga atgtttaggt tttgaagtag
    25981 ttgagaggct tcactctctg cttcccaacc tccaagttcg gcaaactctc cttcgagttc
    26041 ggcagcacga accccgtcct cgtctgagaa atcttccttc atgtagatag catctttctc
    26101 tttcatgatg ctataaagtt tttcatttcc catgataacg acatcaatgg cacgttcatc
    26161 ttcgtagtca aagtgatttt gacgaagaac agagagacgt tcatctggac caagagagat
    26221 gtgaccagta gtaggttcga tatctccagc taaaattttt aaaaaggttg attttccggc
    26281 accattagca ccgattaatc cgtaagtatt tccttctgta aatttgatat tgacatcatc
    26341 aaaaagtttg cgatcactaa aacgtagtga aacatcagat actgtaagca atgtttttct
    26401 cctatatgtg taatatattt attctactag aaaatacaga aatattcaaa tttttatttg
    26461 tcaattttgt gtaaattata tttacagtat cctttacaca aatctgtaaa aagcaaggct
    26521 gatttatttt gataaattac ggttatttca ttaaaaaaat gctataattg aaaggactat
    26581 atcgaaggag aacaaaatga ctaaacccat tattttaaca ggagaccgtc caacaggaaa
    26641 attgcatatt ggacattatg ttggaagtct caaaaatcga gtattattac aggaagagga
    26701 taagtatgat atgtttgtgt tcttggctga ccaacaagcc ttgacagatc atgccaaaga
    26761 tcctcaaacc attgtagagt ctatcggaaa tgtggctttg gattatcttg cagttggatt
    26821 ggatccaaat aagtcaacta tttttattca aagccagatt ccagagttgg ctgagttgtc
    26881 tatgtattat atgaatctag tttcgttagc acgtttggag cgaaatccaa cagtcaagac
    26941 agagatttct cagaaaggat ttggagaaag cattccgaca ggattcttgg tctatccaat
    27001 cgctcaagca gctgatatca cagctttcaa ggctaattat gttcctgttg ggacagatca
    27061 gaaaccaatg attgagcaaa ctcgtgaaat tgttcgttct tttaacaatg catataactg
    27121 tgatgtcttg gtagagccgg aaggtattta tccagaaaat gagagagcag ggcgtttgcc
    27181 tggtttagat ggaaatgcta aaatgtctaa atcactaaat aatggtattt atttagctga
    27241 tgatgcggat actttgcgta aaaaagtaat gagtatgtat acagatccag atcatatccg
    27301 cgttgaggat ccaggtaaga ttgagggaaa tatggttttc cattatctag atgtttttgg
    27361 tcgtccagaa gatgctcaag aaattgctga tatgaaagaa cgttatcaac gaggtggtct
    27421 tggtgatgtg aagaccaagc gttatctact tgaaatatta gaacgtgaac tgggtcctat
    27481 tcgtgagcgc cgtattgaat ttgctaagga tatgggagaa gtttataata tgattcaaaa
    27541 aggtagtgaa agagcgcgtg aagttgcggg tcaaacccta tctgaggtaa aaggggcaat
    27601 gggacttcat tactttaact aagtttattt tacaagaaac tatcttttct atctcgaaga
    27661 aaagatagtt ttttatttac ccctgtaaca tttgacaaat ttttatagaa tggtatgata
    27721 gatacaatat aaaaagagtc aagctcaaaa agaaagaaaa gaggaaactt cgaatgtcta
    27781 attgggacac taaatttttg aaaaaaggtt ttacctttga tgatgtattg cttattccag
    27841 ctgaaagtca tgtgttgcct aacgatgcag atttaacaac taaattggca gataatttga
    27901 ctttaaatat cccaattatt accgctgcca tggacacagt tacagagagt caaatggcca
    27961 ttgctattgc tcgtgcaggc ggtctcggag ttatccataa aaacatgtca attgctcaac
    28021 aagcagacga ggttcgtaag gtaaaacgtt ctgaaaatgg agttattatt gatccgttct
    28081 tcttgacgcc tgaacataca attgctgaag cagatgagct tatgggtcgt taccgcatca
    28141 gtggtgttcc agttgttgaa acacttgaaa atcgtaaatt ggttggtatt ttgacaaacc
    28201 gagatcttcg ttttatttca gattataatc aaccaatttc aaaccatatg actagtgaaa
    28261 atcttgttac tgctcctgtg ggtacggatc ttgcaacggc tgagagtatt cttcaagagc
    28321 atcgtattga aaaacttccg ttggtcgatg aagaaggcag tctttctggt ttgatcacta
    28381 tcaaagatat tgaaaaagtt attgagtttc caaatgcagc taaagatgag tttggtcgtc
    28441 ttctagttgc aggtgcagta ggtgttactt cagatacatt tgaacgtgca gaggctcttt
    28501 ttgaggcagg agcggatgcg attgttattg atactgcaca tggtcattct gcaggtgtct
    28561 tgcgtaaaat tgccgagatt cgtgctcatt tcccagatcg gactttgatt gctggaaata
    28621 ttgctactgc tgaaggtgca cgtgcccttt atgaagcggg tgtagacgtt gttaaggttg
    28681 gtattggacc aggttctatc tgtactactc gtgtgattgc tggtgttggt gttccgcaag
    28741 taacagctat ctacgatgct gcagctgttg cgcgcgaata tggtaaaacg attattgctg
    28801 acggtgggat caagtattct ggagatattg taaaagcact tgctgcaggt ggaaatgctg
    28861 ttatgcttgg atctatgttt gctggaactg atgaagctcc aggcgaaact gaaatcttcc
    28921 aaggacgtaa attcaagact taccgtggta tgggatcaat tgctgctatg aagaaaggtt
    28981 caagcgaccg ttatttccaa ggttctgtca atgaagcaaa caagcttgtt ccagaaggaa
    29041 ttgaaggtcg tgttgcttat aaaggagcgg cagctgatat tgttttccaa atgattggtg
    29101 gtattcgctc tggtatgggt tactgtggtg cagctaacct taaagaacta cacgataatg
    29161 ctcaatttat tgaaatgtct ggtgctggtt tgaaagaaag ccatcctcat gatgtgcaaa
    29221 ttactaatga ggcaccaaat tattctatgt aaaaaacaat gaaaagaact ccagtgaaaa
    29281 caggagttct tttacaatgt tgtcaatttc catttacagc agctttacca tcctgaatag
    29341 tgaagatact tagattttct ggcagatttt gaagatggtc taagcttgtt gttgtgataa
    29401 aggtttggat tgattgagaa atcgtttcta ataattttaa ctgtctagtg ttgtcaagtt
    29461 cactcatcac atcgtcaagc agtaatatag gagattctgt ggtaatgctt tccattaatt
    29521 cgatttctgc taattttatc gagaggacga gactacgatg ttgaccttgg cttccgaaac
    29581 tagcatccat cccatttata taaaaagaaa tgtcatctcg atgaggaccg acaccagtat
    29641 tctttttaaa taaatctctg gatctacttt tttctaaagc aattttgaaa gattcggata
    29701 agttttgttt gtcagttata ttgacagaag attgatagga tattgacaac tcttcgatct
    29761 gattagagag ttcaaaatgt ttcttacgcc caaatgattc tagttttttt atgaaatcta
    29821 agcggtgatt cattacacga catccataat caactagctg atcatctaac acagaaagga
    29881 atgtttcatc tattttttga gctgatttta ggtaagtgtt tctttgcttt aggatgtggt
    29941 tataattggt taagtcagat aaatagattg gcttaatttg cccaagttcc atatcaatga
    30001 attttcgtcg aatcgaaggt gctcctttaa ttagttgtaa atcttcagga gcaaataaga
    30061 caacattcat gtgtcctaca taatctgaaa ggcgtgcctg ttttaagtga ttaacttttg
    30121 ttacacgacc tttttgtgtt agttcgattt ctaggggaat ggatccagtt tttttctgaa
    30181 cgagacctga aagatgaagt tgttcctcat caaaatgaat gagattttta tctgttcgag
    30241 ttcgatgact acgcgttaag gctaaaaaat agatagcctc taacatgttt gtttttcctt
    30301 gtgcattacg tcccaaaaag acattcaatt taggattaaa gtctattttc gtttctttgt
    30361 aattacgaaa agtcttgaga gatagatgtt gtagccacat gattatctac cagggaatcg
    30421 tgaagcttgt tggcttttag gtgatgaagc aggtttcgat ttgtcttttt taactccctt
    30481 attcatcttt ttgacaagtt tagcgatccg ttctttttca actttatcag cttggtattc
    30541 atcttgttct tcagaagtag gttgtgtcaa caagatgtca atgttcatgt cagggatgtc
    30601 aactttatcg ccaatacgaa gtttttttcc acgacggctc tctaattccc tattaaagta
    30661 aacagaatgt tcagagagaa atgatttaat agctcctccg ctatgtgtaa ttccaagttc
    30721 tttgaatagt gcttggaggg taataaattc ttcaaataat ttgtattcca taattcacct
    30781 caatctttgg tattatacca tattttccta aaaatagtga gagagacagc gagaaatgta
    30841 agcgattttt atttcaaaag tgttacaggg aacaagaaaa tttcaggttt tcgtgatata
    30901 atagaagtct gtatataagg aggtaaatca tggagttagt gcatggaatt tcaacacatt
    30961 ttatccaatc aaaaaagttt aaaacaaaca aaattaccgt gcgttttacc gctccattat
    31021 cccttgatac gattgcaggt cacatgttga gtgcaagtat gctagagact gctaatcaga
    31081 tgtaccccac ttctcaagat ttgaggagac acttggccag tctatacggt acagatatgt
    31141 caaccaattg tttcagaaga gggcaaagcc acattataga attgacattt acctatgttc
    31201 gtgatgagtt tttaagtagg aaaaacgtgc taacctctca gattttggaa cttgtaaaag
    31261 aaactctttt ttcacccgta gtagttgata atgggtttga tccggcctta tttgaaattg
    31321 agaaaaaaca attgctagca agtttagcag ctgatatgga tgattctttt tattttgcac
    31381 ataaagaatt ggataaattg ttttttcatg atgaacgtct tcaattggaa tatagtgatt
    31441 tacgaaatcg tattttagct gaaactccac aaagttctta ttcttgtttc caagaatttt
    31501 tagccaatga tcgaatagat ttctttttcc taggtgattt taatgaggtt gaaattcaaa
    31561 atgtattaga atcatttggc tttaaaggtc gaaaaggaga tgtgaaggtt cagtattgtc
    31621 aaccttattc taatatcctt caggaaggta tggttcggaa aaatgtggga caatccattt
    31681 tggaattagg ttatcattac tgttctaaat atggtgatga gcaacattta cccatgattg
    31741 taatgaatgg tttacttggt ggatttgctc actctaagct ctttacaaat gtccgtgaaa
    31801 atgctggatt agcttatacc atttcaagtg agcttgattt atttagtgga ttcttgagga
    31861 tgtatgctgg tatcaatcga gaaaatcgta accaggctcg taaaatgatg aataatcaac
    31921 tgcttgattt aaaaaaaggt tattttacag agtttgagtt aaatcagacc aaggaaatga
    31981 ttcgttggtc gttgttactt tctcaagata atcaatcttc attgattgaa cgtgcttatc
    32041 aaaatgcctt atttggaaaa tcttcagcag actttaaaag ttggattgca aagcttgaac
    32101 aaattgacaa agatgctatt tgtagagtag ctaataatgt gaaactacaa gcgatttact
    32161 ttatggaagg aatagaatga caaaggttgt ttttgaagaa aaatactatc cagctgtaaa
    32221 agaaatggtt tatcgaactc gtttggccaa cggattgaca gttgctcttt tgcctaaaaa
    32281 ggaatttaaa gaggtttacg ggagtgtcac tgtacagttt ggttcggtag atacgtttgt
    32341 cacagaagtt gacggagatg taaaacaata tcctggagga attgctcatt ttcttgaaca
    32401 taaattattt gagagagaag attctagtga tttgatgtcg gcttttacga gtctaggtgc
    32461 agatagtaat gcctttacaa gctttacaaa aacaaactat cttttttcag caacggatta
    32521 ttttttagaa aatttagatt tacttgatga attggtaaca tcagcacact ttactgaagc
    32581 ttccattctg acagagcagg atattattca gcaagaacga gaaatgtacc aagatgatcc
    32641 agattcgtgt ttattctttt caactttagc gaatttgtat cctggtacac ctttagcaac
    32701 tgatatagtt ggaagtgagg agtccatttc ccaaatcaat ctaactaatt tgcaagaaaa
    32761 ttttacaaag ttttacaaac ctgtaaacat gtctctgttt ttagttggta attttgatgt
    32821 ggagcgagta caggactatt ttgaaagcaa agaactgaaa gattcagatt ttcaggaagt
    32881 agcaagagaa aagttgtttt tacagcctgt aaagccaaca gatagtatga gaatggaagt
    32941 atcttctccc aaactagcga ttggagttag aggtaagcga gaagtttctg aagcggattg
    33001 ctatcgacat catattttat taaaattatt gtttgcaatg atgtttggtt ggacttcgga
    33061 tcgttttcaa aaatgttatg aatcaggtaa aattgatgcg tccttatctc tggaagttga
    33121 aataacaagt cgctttcatt ttgtcatgtt gacaatggat acgaaagagc cagttgcttt
    33181 gtctcatcaa tttaggaagg ctattcgtaa ttttacaaag gatttagata ttacagagga
    33241 acatttagat attatcaaaa gagagatgtt tggcgaattt ttcagtagca tgaactctct
    33301 tgaatttatt gcaacgcaat atgatgcttt tgaaaatggt gagacaattt ttgatttgcc
    33361 gaaaatttta caggaaatta ctttagagga tgtccttgat gctggacatc atttaataga
    33421 tgatggtgac atagttgatt ttacaatatt cccatcgtag taacctatca taatagacac
    33481 tagaaagaag ggatgacaag tatgagaaaa aaaacaattg gagaggtttt acgattagct
    33541 agaatcaatc agggattgag tttagatgaa ttgcagaaaa agacagaaat ccagttagat
    33601 atgttggaag caatggaagc agacgatttc gatcaacttc caagtccttt ttacacgcgt
    33661 tctttcttga aaaaatatgc atgggctgtt gagttagatg accaaattgt tttggatgct
    33721 tatgattctg ggagtatgat tacttatgag gaagtagatg ttgatgaaga tgagttgaca
    33781 ggtcgtagac gttcaagtaa gaaaaagaag aaaaaaacat catttttacc tttattttat
    33841 tttatccttt ttgctttatc gattttaatt tttgtgactt attatgtttg gaactatatt
    33901 caaactcaac cagaggagcc ttctctttct aattacagtg tggttcaatc aacaagttca
    33961 actagctctg ttccccactc ctcaagtagt agttcttcta gtatagaatc agctataagt
    34021 gtatcaggcg aaggaaatca tgtagaaatc gcttataaga caagtaagga aacagttaaa
    34081 ttgcaattgg cagtttcaga tgttacaagt tgggtcagtg tttcagaaag cgaacttgag
    34141 ggcggtgtaa ccttatcgcc aaagaagaaa agtgcagaag caacagttgc aactaaaagt
    34201 cctgtaacaa ttacgttagg tgttgtaaaa ggtgttgatt tgacagtaga taatcagact
    34261 gttgatttat cgaaattaac agctcagact ggacaaatca ctgtaacctt tactaaaaat
    34321 taaggaaaaa cgaatgaaaa aagaacaaat tcccaatctc ttaacaatag gtcgaattct
    34381 ctttatacct atttttatct ttattttaac gataggaaat tcgatagaga gtcatatagt
    34441 tgcagctatt atctttgctg ttgccagtat taccgactat ttagatggat atttagctcg
    34501 taaatggaat gtggtcagta attttggtaa atttgcagat cctatggcgg ataagttact
    34561 agttatgtcg gcttttatta tgttgattga gttaggtatg gctccggctt ggattgttgc
    34621 agtgattatc tgtcgtgagt tagctgtgac aggtttaagg cttttattgg ttgaaactgg
    34681 tggaacaatt ttagcagcag caatgcctgg aaaaattaaa acttttagtc agatgtttgc
    34741 cattattttc ttgctattac attggacttt gcttggtcaa gttctacttt atgtagcctt
    34801 atttttcact atctactctg gctatgacta tttcaagggt agtgcctatg tatttaaagg
    34861 gacatttggt tcgaaatgaa atcaataatt gatgtaaaaa atctttcttt tcgctataaa
    34921 gaaaatcaga actactacga tgtgaaggat attacgtttc acgtgaaacg tggagaatgg
    34981 ctttcgattg tagggcataa tggtagtggt aaatcaacga cggttcgatt aattgatggc
    35041 ttactggaag cagaatccgg agagattgta attgatggcc aacgtttgac tgaggaaaat
    35101 gtttggaata tacgtcgtca aatcggtatg gtttttcaaa atccagacaa tcaatttgtt
    35161 ggagcgactg ttgaagatga tgttgctttt ggtttggaaa atcagggact ttctcgtcaa
    35221 gaaatgaaaa agagagtaga agaagctctg gctttagttg gcatgttgga ctttaaaaag
    35281 agagagccag cgcgtctatc aggtggccaa aagcaacgtg tggccattgc aggtgttgta
    35341 gccctaagac cagctatttt aatcttagat gaagcaacga gtatgttgga tcctgagggg
    35401 cgtagagaac ttattgggac agtaaaagga attcgaaaag actatgatat gacggtcatt
    35461 tctattaccc atgatttgga agaagtcgcc atgagtgatc gcgtattggt catgaaaaaa
    35521 ggggaaattg aatcaactag tagtccaagg gagcttttct ctcgaaatga tttagatcaa
    35581 attggattag acgatccttt tgctaatcaa ttaaaaaaat ctttgagcca gaatggctat
    35641 gatttacctg aaaattattt gacagaaagt gagctagagg ataagctatg ggaattgctc
    35701 tagaaaatgt gaattttaca tatcaagaag gtactccctt agcttcagca gctttgtcgg
    35761 atgtttcttt gacgattgaa gatggctctt atacagcttt aattgggcac acaggtagtg
    35821 gtaaatcaac tattttacaa ttcttaaatg gtttattggt gccaagtcaa gggagtgtga
    35881 ggatttttga taccttaatc acctcgactt ctaaaaataa agatattcgt caaattagaa
    35941 aacaggttgg cttggtattt cagtttgctg aaaatcagat ttttgaagaa acggttttga
    36001 aggacgttgc ttttggaccg caaaattttg gagtttctga agaagatgct gtgaagactg
    36061 cgcgtgagaa actggctctg gttggaattg atgaatcact ttttgatcgt agtccgtttg
    36121 agctgtcagg gggacaaatg agacgtgttg ccattgcagg catacttgcc atggagccat
    36181 ctatattagt cttagatgag ccaacagctg gtctagatcc tctagggaga aaagagttga
    36241 tgaccctgtt caaaaaactc caccagtcag ggatgaccat cgtcttggta acgcatttga
    36301 tggatgatgt tgctgaatat gctaatcaag tctatgtaat ggaaaaggga cgtttagtaa
    36361 aggggggcaa accaagtgat gtctttcaag acgttgtttt tatggaagaa gttcagttgg
    36421 gagtacctaa aattacggcc ttttgtaaac gattggctga tagaggcgtg tcatttaaac
    36481 gattaccgat taagatagag gagttcaagg agtcgctaaa tggatagtat gattttgggg
    36541 cgttatatcc caggggattc gattgttcac cgattggatc cacgtagcaa attgcttgct
    36601 atgatgctac tgattttgat tgtgttttgg gctaataacc ccttgacgaa tctgattctt
    36661 tttatagcga cagggatatt tattgccttg tcaggagtat ctctttcatt ttttattcag
    36721 ggcttgaagt ctatgttttt cttgattgcc ttcacaacta tttttcaact atttttcatt
    36781 tctaatggga atgttttatt tgagttttcg tttgtgagaa tcacggatta tgctttgcaa
    36841 caagctggga ttattttttg tcgctttgta ttgattattt tcttttcaac tttgttaacc
    36901 ttaacaacca tgcctttaag tttggcatca gctgtcgaag ctttattagc acctttaaag
    36961 cgtgtgaaag ttccagttca tgaaattgga ttgatgctgt ctatgagttt gcgttttgtc
    37021 ccaaccttga tggatgatac gacgcggatt atgaatgcac agaaagctcg tggagtggat
    37081 tttggagaag gaagtatcgt tcaaaaagta aaggcgatga ttcccatttt gattcctctt
    37141 tttgcgacaa gtttaaaacg tgcagattcc ttggctatcg ctatggaagc gcgtggctat
    37201 cagggtggaa aaggcagaag tcaataccga caattgaaat ggactctaaa ggatacgctg
    37261 accattcttg ttattctcgt acttggttgt tgtttatttt tcttaaaatc ttagtagctt
    37321 tcaggaattg ataaaaagtt actgtaacag tttttgatag aaaggtaggg atatgaaccg
    37381 ttttaaaaaa tcaaaatatg tcattattgt ttttgtcact gttctgcttg tgtcagctct
    37441 cttagcgacg acttattcaa gtacaattgt gacaaaatta ggagatggaa tctcattggt
    37501 tgatagagtt gtacaaaaac cttttcagtg gtttgattct gtcaaatcag atttggctca
    37561 tttgacacga acatataatg aaaatgaaag tttgaagaaa cagctttacc aattagaagt
    37621 taaatcaaat gaggtggaaa gtttaaagac agaaaatgaa caactgcgcc aattgcttga
    37681 tatgaagtct aaattgcaag ccacaaagac tttagcagca gatgttatta tgcgttctcc
    37741 ggtatcttgg aagcaggagt tgaccttaga tgcaggtaga tcaaaaggtg cttctgagaa
    37801 catgttagct attgcaaatg gtggcttgat tgggagtgtt tcaaaagtag aggagaactc
    37861 tactatagtc aaccttctga caaatacgga aaatgctgat aagatttctg ttaaaattca
    37921 acatggctct actacaattt atggaattat tattggctat gacaaggaaa atgacgttct
    37981 taaaattagc caattaaata gtaatagcga tattagtgcg ggagataagg tgactactgg
    38041 tggattagga aactttaacg ttgctgatat tcctgttggt gaagtggttg ccacaacgca
    38101 tagtacagac tatttgacac gagaagtaac tgttaaattg agtgcagata ctcataatgt
    38161 agatgtgata gaattagtgg ggaattcata atgagacagt tgaagcgagt tggagtattt
    38221 ttattgcttc ctttctttgt tctaattgac gcccatatta gccagcttct gggctcattt
    38281 ttcccccatg tacatttggc tagtcatttt ctttttctat ttctcttatt tgagacgata
    38341 gaagtatcag agtatctcta cctagtctat tgttttgtta taggcttggt ttatgatgtt
    38401 tactttttcc atctaatagg gattacaact ctcttattta tcttattggg agccttcctt
    38461 cataaattga atagtgttat tttgttgaat cgttggacaa gaatgctagc tatgattgtg
    38521 ctgacattcc tgtttgaaat gggtagttat cttttggctt ttatggtagg gttgacagta
    38581 gatagcatgt cgatttttat agtctatagc ttggtaccga cgatgatttt aaatttttta
    38641 tggattactg tttttcaatt tatttttgaa aaatattatc tataagaacg acatataaat
    38701 gtaacaaagg cgtaatattt attaggcctt tttttggtat actagtattg tctttaaaag
    38761 aaggagtatc tacgtaatat gaagaaaaaa atcttagcgt cacttttatt aagtacagta
    38821 atggtttctc aagtagctgt tttaacaact gcgcatgcag aaacgactga tgacaaaatt
    38881 gctgctcaag ataataaaat tagtaactta acagcacaac aacaagaagc ccaaaaacaa
    38941 gttgaccaaa ttcaggagca agtatcagct attcaagctg agcagtctaa cttgcaagct
    39001 gaaaatgata gattacaagc agaatctaag aaactcgagg gtgagattac agaactttct
    39061 aaaaacattg tttctcgtaa ccaatcgttg gaaaaacaag ctcgtagtgc tcaaacaaat
    39121 ggagccgtaa ctagctatat caataccatt gtaaactcaa aatcaattac agaagctatt
    39181 tcacgtgttg ctgcaatgag tgaaatcgta tctgcaaaca acaaaatgtt agaacaacaa
    39241 aaggcagata aaaaagctat ttctgaaaaa caagtagcaa ataatgatgc tatcaatact
    39301 gtaattgcta atcaacaaaa attggctgat gatgctcaag cattgactac gaaacaggca
    39361 gaactaaaag ctgctgaatt aagtcttgct gctgagaaag cgacagctga aggggaaaaa
    39421 gcaagtctat tagagcaaaa agcagcagct gaggcagagg ctcgtgcagc tgcggtagca
    39481 gaagcagctt ataaagaaaa acgagctagc caacaacaat cagtacttgc ttcagcaaac
    39541 actaacttaa cagctcaagt gcaagcagta tctgaatctg cagcagcacc tgtccgtgca
    39601 aaagttcgtc caacatacag tacaaacgct tcaagttatc caattggaga atgtacatgg
    39661 ggagtaaaaa cattggcacc ttgggctgga gactactggg gtaatggagc acagtgggct
    39721 acaagtgcag cagcagcagg tttccgtaca ggttcaacac ctcaagttgg agcaattgca
    39781 tgttggaatg atggtggata tggtcacgta gcggttgtta cagctgttga atcaacaaca
    39841 cgtatccaag tatcagaatc aaattatgca ggtaatcgta caattggaaa tcaccgtgga
    39901 tggttcaatc caacaacaac ttctgaaggt tttgttacat atatttatgc agattaattt
    39961 acagagggac tcgaatagag ccctcttttc aggttttacc gtgacaatcc ctattaaaaa
    40021 ttatatcaaa atagcttgaa aatattggaa aagtatggta aaatgaaaat tgtcgtgtga
    40081 acgataatac tcattcttga tgaattgtga agcagttgcc cttgggtcgt tttgcgagtt
    40141 gaagtcaaga agaggaaaaa aacaaaaagg agaaatactc atggcagtaa tttcaatgaa
    40201 acaacttctt gaggctggtg tacactttgg tcaccaaact cgtcgctgga atcctaagat
    40261 ggctaagtac atctttactg aacgtaacgg aatccacgtt atcgacttgc aacaaactgt
    40321 aaaatacgct gaccaagcat acgacttcat gcgtgatgca gcagctaacg atgcagttgt
    40381 attgttcgtt ggtactaaga aacaagcagc tgatgcagtt gctgaagaag cagtacgttc
    40441 aggtcaatac ttcatcaacc accgttggtt gggtggaact cttacaaact ggggaacaat
    40501 ccaaaaacgt atcgctcgtt tgaaagaaat taaacgtatg gaagaagatg gaactttcga
    40561 agttcttcct aagaaagaag ttgcacttct taacaaacaa cgtgcgcgtc ttgaaaaatt
    40621 cttgggtggt atcgaagata tgcctcgtat cccagatgtg atgtacgtag ttgacccaca
    40681 taaagagcaa atcgctgtta aagaagctaa aaaattggga atcccagttg tagcgatggt
    40741 tgacaccaat actgatccag atgatatcga tgtaatcatc ccagctaacg atgacgctat
    40801 ccgtgctgtt aaattgatca cagctaaatt ggctgacgct attatcgaag gacgtcaagg
    40861 tgaggatgca gtagcagttg aagcagaatt tgcagcttca gaaactcaag cagattcaat
    40921 tgaagaaatc gttgaagttg tagaaggtga caacgcttaa tttatacaaa tagtaattac
    40981 ctaggagggc ggggcttagc ccggctctcc tattttcaaa aaatatagga gaattaaaat
    41041 ggcagaaatt acagctaaac ttgtaaaaga gttgcgtgaa aaatctggtg ccggtgttat
    41101 ggacgctaaa aaagcgcttg tagaaacaga cggtgacatc gaaaaagcga ttgaattgct
    41161 tcgtgaaaaa ggtatggcta aggcagctaa gaaagctgac cgtgttgctg cagaaggttt
    41221 gactggtgtt tatgttaacg gtaatgttgc agcagttatt gaagtaaacg ctgaaactga
    41281 cttcgttgca aaaaacgctc aattcgttga attggtaaat actacagcta aagtcattgc
    41341 tgaaggaaaa cctgctaaca acgaagaagc tcttgctttg ataatgcctt caggtgaaac
    41401 tcttgaagct gcatacgtat ctgcaacagc aactatcgga gagaaaatct cattccgtcg
    41461 ctttgcattg attgaaaaaa cagacgcaca acactttgga gcataccaac ataacggtgg
    41521 acgtatcggt gttatttcag ttgttgaagg tggagacgaa gcacttgcta aacaattgtc
    41581 aatgcacatc gcagcgatga aaccaacagt tctttcttac aaagaattgg atgagcaatt
    41641 cgttaaagat gagttggcac aattgaatca cgttatcgac caagacaacg aaagccgtgc
    41701 aatggttaat aaaccagctc ttccacactt gaagtatgga tcaaaagctc aattaactga
    41761 tgatgttatt gctcaagctg aagctgacat caaagctgaa ttggctgcag aaggcaaacc
    41821 agaaaaaatc tgggacaaaa ttattccagg taaaatggat cgcttcatgc ttgataacac
    41881 taaagttgac caagcttaca cacttcttgc acaagtttac atcatggatg acagcaagac
    41941 agttgaagca taccttgaat cagttaacgc ttcggtagtt gagtttgctc gctttgaagt
    42001 tggtgaaggt atcgagaaag ctgcaaacga cttcgaagct gaagttgcag ctacaatggc
    42061 agcagccttg aataactaat aatagaaagg aagcaaattg cttccttttt tgtatagggc
    42121 ttagattttt cctgaaattg ttttttcccc agtctcactc gattagaata attaaaacaa
    42181 aaagccctat aataagggct aagtgcattt aggagactat acttcaaatt catagtaagc
    42241 gcgtcataac aaggtatcta tcctaattcc ccaacttcca gtataccaga taaaaaataa
    42301 ttatcggagg aaaggtattg tactatgata attcaactaa gtgatttagg tcaagttcac
    42361 cttgtttgtg gcaagacaga tatgaggcag ggaatagact cattagccta tgtagttaaa
    42421 acccactttg aattggatcc tttctccgat caagtctttc tcttttgtgg tggacgtaaa
    42481 gaccgcttta aagttcttta ctgggatggt caaggatttt ggatattata taaacgcttt
    42541 gagaacggaa aactgacttg gtccagtaca gaaaaggatg tcaaagctct cacatctgaa
    42601 caagtagatt ggctgatgaa gggcttttct atcactcccc aaatatagtg gatttaaact
    42661 agaatagtac acctctgctt ctaaaacatt gttagaaatc gatttgacta tcctgttctt
    42721 atttcatttt actataaatt catcagaaag tcgtgatttc tattgaaatg aggactttct
    42781 ttttatactc atctgttttc aaaaagcatt ctagtccgtc tccgattaac gatggacttt
    42841 atcacctcct tctccagtcc ttgtatgaca tcttccaaag ttcgaaaggc tttattctta
    42901 aatccacgtt tacgaatctc tttccacact tgttcaatgg ggttcatctc tggtgtgtat
    42961 ggaggaataa atgcaaagcc aatattagtc ggaatcttta aggtacttga tttatgccat
    43021 atagcattgt ccataacgag taaaagataa tcatctggat aagcttgtga aagctcctat
    43081 tcctaaagcc cctttagcgc ataactttgg ctcagcttct attatcgctc acaccatcca
    43141 tcagaagttt aatctgaagg tacccaatta tcgccaagaa gaagattggg ctaggatggg
    43201 tttaccaatc acacgtaagg aaatctctaa ttggcatatc aagacgagtc aatactattt
    43261 ggagcccctt tataacctct tgcgagagag actattgact cagcccttac ttcatgcgga
    43321 tgaaacttct tatagggtgc tagagagtga tagtcagctg acttactatt ggactttttt
    43381 gtctgggaaa gctgagaaac aagggattac gctttaccat catgttctaa tcgatttgtt
    43441 catatcttat ttcaatccat tataaatagt gagaaatatc tatcctatct tctagaatgt
    43501 cttccaaacg tggaaactct cgtaaacaaa gaggttttag aggcctattt accatggact
    43561 aaagttgtac aagaaaagtg caaataagaa atctccagat taggaactat ccgtgagttc
    43621 tctagtctgg agatttttca atagacttcg ttattggacg gttacaattc ataaagtgct
    43681 gtagagagat aacgttcacc gttatctggt gctagggcaa ggactttttt acctgtacct
    43741 aattttttgg caacctcgat ggctccgtag atagctgcag ctgaggaaat ccctacaagg
    43801 aagccttctt ttccaccaat ttcacgtccg agtgcaagag cgtcatctga tgttacacga
    43861 acgataccat cataggcttt agtatcaagt gtatcaggaa taaatccagc tgagatacct
    43921 tgaattttgt gaggaccagg tttttcacca gatagaatag cagattcatc tgcttctact
    43981 gcaaaaactt gaatgttaga attttctgat ttgagtgcat gagaaacacc agaaatcgtt
    44041 ccaccagtac ctactccagc aacaaaggca tctaatccat ctttaccgaa agcagctagt
    44101 atctcagctc ctgttgttct ttcgtgtact tctggattag ctggattgtc aaattgaaga
    44161 ggaaggaaac catcacgttc agcagcgatt tcttgagcct tagcaatagc acctttcatt
    44221 ccctcgctac caggagttag gacgagttca gcaccataag cttggataat tttacgtcgt
    44281 tctacactca tagtttcagg cataacgatg acgactttat accctttagc agcacctacc
    44341 catgaaagtc caataccggt gtttccactt gttgcttcaa caatagtaga accaggtttc
    44401 agaataccat cttgttcagc tttttcaatc atgctaaggg caatacggtc ttttacagat
    44461 gaaccaggat taaatgcttc aagctttata tagacgtctg cagcaccttc tggcacgatg
    44521 ttgttaagtt taacaatcgg tgtttgaccg attaattcag taatgttgtt ataaatagac
    44581 atatgaatac ctctttgtat aagatatctt tagtataacg ctatccatac catttgtaaa
    44641 atatagaaat cctatcgaag cgataggatt tctatatatc atagatcaaa gtcattaatt
    44701 ttcaagtgat tgcgttcagc taattctagt aaataggtgt gaaggaaaac gatatcaggt
    44761 ttcgtttgaa ttgcttcatt ttctagtata ttttggtacg catcttttta ttttgctcgc
    44821 taaagtagtt gtgagaatgt caacgaaacg ctgtattatt cattgtttac actaagttta
    44881 caggaacttc aacctctcgt aaaccttggt cagttaaagt gacttttcca ttaaaaaact
    44941 ccacaagtgc agctttaata gtttcttttt cttctttatc aacataaatc atcgtatcga
    45001 cttgatctgt aaagtttgta tccagctcca tgagaccatg ttctttaagg aagttactgt
    45061 actcttggta ctgagcataa gacatttgaa tagcaatgcc agcctgttct tttatttcaa
    45121 taataccaat ttctttgaca gctaaggcga cactgccggc gtaagcacga attagtcctc
    45181 cagcgcctag tttaatacca ccaaagtagc gtgtcacgac cacacagaca ttggtgagat
    45241 tgtgattttc tagtacccca agcatgggaa caccagcagt accactaggc tcaccatcat
    45301 cacttgtacg tttaatttca ctacgttctc caataatgaa ggcagagcag ttatgtgtcg
    45361 ctttgtagtg ttcttttttg atggcagtaa tgaagtcacg agcctcttct tcgctataaa
    45421 cacgcttggc atggcagata aagcgagatt ttttgatttc ttcttggact tgaccgtcct
    45481 ctttaattgt cctaaattcc atgatttaat tgtactaaaa aatcatctaa agtgctagtt
    45541 tttacgaata aagaagtatg aaagtaaatt tagattatct cggtcgttta tttactgaga
    45601 atgaattaac agaagaagaa cgtcagttgg cggagaaact tccagcaatg agaaaggaga
    45661 aggggaaact tttctgtcaa cgctgtaata gtactattct agaagaatgg tatttgccca
    45721 tcggtgctta ctattgtcga gagtgcttgc tgatgaagcg agtcagaagt gatcaaactt
    45781 tatactattt tccgcaggag gattttccaa agcaagatgt tctcaaatgg cgcggccaat
    45841 taactccttt tcaagagaag gtgtcagagg gattgcttca agtagtagac aagcaaaagc
    45901 caaccttagt tcatgcggta acaggagctg gaaagacaga aatgatttat caagtagtgg
    45961 ctaaagtgat caatgcgggt ggtgcagtgt gtttggctag tcctcgcata gatgtttgtt
    46021 tggagctgta caagcgcctg caacaggatt tttcttgcgg gatagctttg ctacatggag
    46081 aatcggaacc ttattttcga acaccactag ttgttgcaac aacccatcag ttattgaagt
    46141 tttatcaagc ttttgatttg ctgatagtgg atgaagtaga tgcttttcct tatgttgata
    46201 atcccatgct ttaccacgct gtcaagaata gtgtaaagga gaatggattg agaatctttt
    46261 taacagcgac ttcgaccaat gagttagata aaaaggtccg tttaggagaa ctaaaaagac
    46321 tgaatttacc gagacggttt catggaaatc cgttgattat tccaaaacca atttggttat
    46381 cggattttaa tcgctactta gacaagaatc gtttgtcacc aaagttaaag tcctatattg
    46441 agaagcagag aaagacagct tatccgttac tcatttttgc ttcagaaatt aagaaagggg
    46501 agcagttagc agaaatctta caggagcaat ttccaaatga gaaaattggc tttgtatctt
    46561 ctgtaacaga ggatcgatta gagcaagtac aagcttttcg agatggagaa ctgacaatac
    46621 ttatcagtac gacaatcttg gagcgcggag ttaccttccc ttgtgtggat gttttcgtag
    46681 tagaggccaa tcatcgtttg tttaccaagt ctagtttgat tcagattggt ggacgagttg
    46741 gacgaagcat ggatagaccg acaggagatt tgcttttctt ccatgatggg ttaaatgctt
    46801 caatcaagaa ggcgattaag gaaattcaga tgatgaataa ggaggctggt ctatgaagtg
    46861 cttgttatgt gggcagacta tgaagactgt tttaactttt agtagtctct tacttctgag
    46921 gaatgatgac tcttgtcttt gttcagactg tgattctact tttgaaagaa ttggggaaga
    46981 gaactgtcca aattgtatga aaacagagtt gtcaacaaag tgtcaagatt gtcaactttg
    47041 gtgtaaagag ggagttgaag tcagtcatag agcgattttt acttacaatc aagctatgaa
    47101 ggattttttc agtcggtata agtttgatgg agacttcctg ttaagaaaag ttttcgcttc
    47161 atttttaagt gaggagttga aaaagtacaa agagtatcaa tttgttgtaa ttcccctaag
    47221 tcctgataga tatgctaata gaggatttaa tcaggttgag ggcttggtag aggcagcagg
    47281 ctttgagtat ctggatttat tagagaaaag agaagagaga gccagttctt ctaaaaatcg
    47341 ttcagagcgc ttggggacag aacttccttt ctttattaaa agtggagtca ctattcctaa
    47401 aaaaatccta cttatagatg atatctatac tacaggagca actataaatc gtgttaagaa
    47461 actgttggaa gaagctggtg ctaaggatgt aaaaacattt tcccttgtaa gatgaggaaa
    47521 aaatttgcaa aaatagaatg aaagcgttat aataaaatca taaaaacaaa aatgtttaga
    47581 aagaaggtac tcatatgatt aaatatagta tccgtggtga aaacctagaa gtaacagaag
    47641 caattcgtga ttatgtagtt tctaaactcg aaaagatcga aaagtacttc caaccagaac
    47701 aagagttgga tgcccgaatt aacttaaaag tttatcgtga aaaaacggct aaagtggaag
    47761 taacgattcc gcttggatct attactcttc gcgcagaaga tgtatctcaa gatatgtatg
    47821 gttcaattga ccttgtaact gataaaattg aacgtcagat tcgtaaaaat aaaacaaaaa
    47881 tcgagcgtaa aaataaaaat aaggtagcaa ctggtcaatt atttacagat gctttggtgg
    47941 aagattcaaa tattgtccag tctaaagttg ttcgttcaaa acaaattgat ttaaaaccaa
    48001 tggatttgga agaagcaatt ctacaaatgg atttattggg gcatgatttc tttatctatg
    48061 tggatgttga agatcagaca accaatgtga tttatcgtcg tgaggatggc gaaattggtt
    48121 tgttagaggt taaagaatct taatttcaat atgtgtaaag gtaggtttac tgaattgtaa
    48181 actacctttt tcttataatt gatagaatta ctgattacac ttttaaaaag tcgctttttg
    48241 aggggtatta tggtataatg ggtgccaaga ggttttgaat gaaaaaattt tatgtaagtc
    48301 caatttttcc tattctagta ggattgattg cgtttggagt cttatccact ttcattattt
    48361 ttgttaataa taatctgttg acggttttaa ttttgtttct ttttgtagga ggctatgttt
    48421 ttttatttaa gaaactgaga gtgcattata caaggagtga tgtagaacag atacagtatg
    48481 taaaccacca agcggaagaa agtttgacat ctctattgga acaaatgcct gtaggtgtta
    48541 tgaaattgaa tttatcttct ggagaggttg agtggtttaa tccctatgct gaattgattt
    48601 tgaccaagga agatggtgat tttgatttag aagctgttca aacgattatc aaggcttcag
    48661 taggaaatcc gtctacttat gccaagcttg gtgagaagcg ttatgctgtt catatggatg
    48721 cttcttccgg tgttttgtat tttgtagatg tatccaggga acaagccata acagatgaat
    48781 tggtaacaag tcgaccagtg attgggattg tctctgtgga taattatgat gatttggagg
    48841 atgcaacttc tgagtcagat attagtcaaa tcaatagttt tgtagctaat tttatatcag
    48901 agttttcaga aaaatacatg atgttttctc gtcgggtaag tatggatcga ttttatctat
    48961 ttactgacta cacggtgctt gagggcttga tgaatgataa attttctgtt attgatgctt
    49021 tcagagaaga gtcgaaacag agacagttgc ccttgacctt aagtatggga ttttcttatg
    49081 gcgatggaaa tcatgatgag atagggaaag ttgctttgct caatttgaac ttggctgaag
    49141 tacgtggtgg cgaccaggtg gttgttaagg aaaacgacga aacgaaaaat ccagtttatt
    49201 ttggtggtgg gtctgctgct tcaatcaagc gtacacggac tcgtacgcgc gctatgatga
    49261 cagctatttc agataagatt cggagtgtag atcatgtttt tgtagtcggt cacaaaaatt
    49321 tagacatgga tgctttgggc tctgctgtag gtatgcagtt gttcgccagc aatgtgattg
    49381 aaaatagcta tgctctttat gatgaagaac aaatgtctcc agatattgaa cgagctgttt
    49441 cattcataga aaaagaagga gttacgaagt tgttgtctgt taaggatgca atggggatgg
    49501 tgaccaatcg ttctttgttg attcttgtag accattcaaa gacagcctta acattatcaa
    49561 aagaatttta tgatttattt acccaaacca ttgttattga ccaccataga agggatcagg
    49621 attttccaga taatgcggtt attacttata tcgaaagtgg tgcaagtagt gccagtgagt
    49681 tggtaacgga attgattcag ttccagaatt ctaagaaaaa tcgtttgagt cgtatgcaag
    49741 caagtgtctt gatggctggt atgatgttgg atactaaaaa tttcacctcg cgagtaacta
    49801 gtcggacatt tgatgttgct agctatctca gaacgcgcgg aagtgatagt attgctatcc
    49861 aggaaatcgc tgcgacagat tttgaagaat atcgtgaggt caatgaactt attttacagg
    49921 ggcgtaaatt aggttcagat gtactaatag cagaggctaa ggacacgaaa tgctatgata
    49981 cagttgttat tagtaaggca gcagatgcca tgttagccat gtcaggtatt gaagcgagtt
    50041 ttgttcttgc gaagaataca caaggattta tctctatctc agctcgaagt cgtagtaaac
    50101 tgaatgtaca acggattatg gaagagttag gcggtggagg ccactttaat ttggcagcag
    50161 ctcaaattaa agatgtaacc ttgtcagaag caggtgaaaa actgacagaa attgtattaa
    50221 atgaaataaa ggaaaaggag aaagaagaat gaaagtaatc tttttagcag atgttaaagg
    50281 aaaaggtaaa aaaggcgaaa ttaaggaagt accaacaggg tatgcgcaaa actttcttat
    50341 caaaaagaat ctagccaaag aagcgactgc tcaagctgta ggtgaacttc gtggtaaaca
    50401 aaaatcggaa gaaaaagctc acgctgagat gattgcagaa gggaaagcaa ttaaagcaca
    50461 acttgaagca gaagaaactg ttgtagaatt tgttgaaaaa gttggtccag atggtcgtac
    50521 ctttggttct attaccaata agaagattgc agaagaatta caaaagcaat ttggaattaa
    50581 gattgataaa cgtcatattc aagtacaagc tccgattcga gcggttggtt tgattgatgt
    50641 gccagtgaaa atctatcaag atatcacaag tgtaatcaat cttcgtgtga aagaaggata
    50701 agtttacacc ttcttgacaa gattgtaaaa ggaagggaag tctgatggca gaagtagaag
    50761 agttacgagt acaacctcaa gatatcttag ctgagcaatc cgttttaggg gctatcttta
    50821 ttgatgagag taaacttgtt tttgtgcgag aatacattga gtctcgggac ttttttaagt
    50881 atgcccatcg tttgattttc caagccatgg tcgatttatc cgatcgtggt gatgccatag
    50941 atgcaacaac ggttcgtact atccttgata atcaaggtga tttacagaat attggtggct
    51001 tgtcttactt ggttgagatt gtcaattctg tgccaacttc tgctaatgcg gagtattatg
    51061 ctaagattgt tgcagaaaaa gcaatgctac gtcgtttaat tgccaagttg acagagtctg
    51121 tcaaccaagc ttacgaagcg tcacaaccag ctgatgaaat tattgctcag gcagaaaaag
    51181 ggctgattga tgtcagtgaa aatgcaaatc gaagcgggtt taagaacatt cgagatgtgt
    51241 tgaatctcaa ctttggaaat ctggaagctc gctcgcaaca aacgaccgat attacaggta
    51301 ttgcgacagg ttatcgtgat ttggatcata tgacaacagg acttcatgag gaggagttga
    51361 ttatcttagc agctcgtcca gcagttggta agacagcatt tgccttgaat atcgctcaga
    51421 atattgggac taagttggac aaaacggttg ctattttttc actcgaaatg ggtgcggaaa
    51481 gcttggtaga ccgtatgtta gctgcagaag gcttggtgga gtcacattct atccgtacag
    51541 ggcaattgac agatgaggag tggcaaaaat atactattgc tcagggtaat ctagctaacg
    51601 ccagtatcta tatcgatgat acgccaggta ttcggattac agagattcgt tctcgttctc
    51661 gtaaattggc tcaagaaact ggaaatcttg gtttgatttt gatagactat ttgcaactta
    51721 tcacgggaac tggtcgagaa aatcgtcaac aagaagtttc tgaaatttct cgtcagttga
    51781 aaatactagc caaggaattg aaggttccag taatcgctct gagtcagctt tctcgtggtg
    51841 tagaacaacg tcaggacaag agaccggtct tgtctgatat tcgtgaatct gggtctattg
    51901 agcaggacgc tgatatcgta gcttttctct atcgcgatga ctactatgaa cgtggtggtg
    51961 aagaagagga gggtatccca aataataagg tggaagttat tatcgagaaa aaccgtagtg
    52021 gagctcgtgg aacagtggaa ttgattttcc aaaaagaata caataaattt tcaagtatct
    52081 caaagaggga ggcataagat gtcagatgca tttacagatg tagccaagat gaaaaaaatc
    52141 aaagaagaaa tcaaggcaca tgagggacaa gtcgtagaaa tgactttgga gaatggtcgt
    52201 aagcgccaaa aaaatagatt gggtaagcta attgaagttt atccatccct atttattgtg
    52261 gagtttgggg atgtggaagg agataaacaa gttaatgttt acgttgaatc ctttacttac
    52321 tcagatattc ttacagaaaa gaatttgatt cattatcttg actaaagtga g
//
LOCUS       DAVEHY010000012        52284 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVEHY010000012 DAVEHY010000000
VERSION     DAVEHY010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.012"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            25..1086
                     /gene="dinB"
                     /locus_tag="VUZ44_000847"
     CDS             25..1086
                     /gene="dinB"
                     /locus_tag="VUZ44_000847"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU0319793.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSN
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(1233..2078)
                     /locus_tag="VUZ44_000848"
     CDS             complement(1233..2078)
                     /locus_tag="VUZ44_000848"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU0319794.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGIAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            2334..3362
                     /locus_tag="VUZ44_000849"
     CDS             2334..3362
                     /locus_tag="VUZ44_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU0319795.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     FRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILAEIRNI
                     HAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACARFSPAFK
                     AYLKTKLE"
     gene            complement(3663..5552)
                     /locus_tag="VUZ44_000850"
     CDS             complement(3663..5552)
                     /locus_tag="VUZ44_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU0319796.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRGA
                     KAADEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            5690..7255
                     /locus_tag="VUZ44_000851"
     CDS             5690..7255
                     /locus_tag="VUZ44_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU0319797.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            7255..7995
                     /locus_tag="VUZ44_000852"
     CDS             7255..7995
                     /locus_tag="VUZ44_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU0319798.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(8104..8319)
                     /locus_tag="VUZ44_000853"
     CDS             complement(8104..8319)
                     /locus_tag="VUZ44_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319799.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(9190..10440)
                     /gene="ilvA"
                     /locus_tag="VUZ44_000854"
     CDS             complement(9190..10440)
                     /gene="ilvA"
                     /locus_tag="VUZ44_000854"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU0319800.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(10490..10846)
                     /locus_tag="VUZ44_000855"
     CDS             complement(10490..10846)
                     /locus_tag="VUZ44_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU0319801.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(11084..11320)
                     /locus_tag="VUZ44_000856"
     CDS             complement(11084..11320)
                     /locus_tag="VUZ44_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319802.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(11427..12449)
                     /gene="ilvC"
                     /locus_tag="VUZ44_000857"
     CDS             complement(11427..12449)
                     /gene="ilvC"
                     /locus_tag="VUZ44_000857"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU0319803.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(12515..12991)
                     /gene="ilvN"
                     /locus_tag="VUZ44_000858"
     CDS             complement(12515..12991)
                     /gene="ilvN"
                     /locus_tag="VUZ44_000858"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU0319804.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(12984..14684)
                     /locus_tag="VUZ44_000859"
     CDS             complement(12984..14684)
                     /locus_tag="VUZ44_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU0319805.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(14884..16551)
                     /locus_tag="VUZ44_000860"
     CDS             complement(14884..16551)
                     /locus_tag="VUZ44_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU0319806.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(16554..16919)
                     /locus_tag="VUZ44_000861"
     CDS             complement(16554..16919)
                     /locus_tag="VUZ44_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU0319807.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(17076..17264)
                     /locus_tag="VUZ44_000862"
     CDS             complement(17076..17264)
                     /locus_tag="VUZ44_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU0319808.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(17380..17556)
                     /locus_tag="VUZ44_000863"
     CDS             complement(17380..17556)
                     /locus_tag="VUZ44_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU0319809.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(17667..17864)
                     /locus_tag="VUZ44_000864"
     CDS             complement(17667..17864)
                     /locus_tag="VUZ44_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU0319810.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(18119..19663)
                     /locus_tag="VUZ44_000865"
     CDS             complement(18119..19663)
                     /locus_tag="VUZ44_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU0319811.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            19876..20178
                     /gene="gatC"
                     /locus_tag="VUZ44_000866"
     CDS             19876..20178
                     /gene="gatC"
                     /locus_tag="VUZ44_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU0319812.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTNRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            20178..21644
                     /gene="gatA"
                     /locus_tag="VUZ44_000867"
     CDS             20178..21644
                     /gene="gatA"
                     /locus_tag="VUZ44_000867"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU0319813.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPATFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            21644..23086
                     /gene="gatB"
                     /locus_tag="VUZ44_000868"
     CDS             21644..23086
                     /gene="gatB"
                     /locus_tag="VUZ44_000868"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU0319814.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            23215..23775
                     /gene="efp"
                     /locus_tag="VUZ44_000869"
     CDS             23215..23775
                     /gene="efp"
                     /locus_tag="VUZ44_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU0319815.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            23797..24186
                     /locus_tag="VUZ44_000870"
     CDS             23797..24186
                     /locus_tag="VUZ44_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU0319816.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            24179..24601
                     /gene="nusB"
                     /locus_tag="VUZ44_000871"
     CDS             24179..24601
                     /gene="nusB"
                     /locus_tag="VUZ44_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU0319817.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(24650..24878)
                     /locus_tag="VUZ44_000872"
                     /pseudo
     CDS             complement(24650..24878)
                     /locus_tag="VUZ44_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(24900..25349)
                     /locus_tag="VUZ44_000873"
     CDS             complement(24900..25349)
                     /locus_tag="VUZ44_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319818.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIELYVTIILGLGADVYSL
                     ILTMVLVGSFLLLIWRLKKKKSWNWSFVFSLFATYVVYQILGNFWARYAHLINHRNIH
                     DEYFTVVLSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(25367..25551)
                     /gene="briC"
                     /locus_tag="VUZ44_000874"
                     /pseudo
     CDS             complement(25367..25551)
                     /gene="briC"
                     /locus_tag="VUZ44_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
     gene            complement(25709..26476)
                     /locus_tag="VUZ44_000875"
     CDS             complement(25709..26476)
                     /locus_tag="VUZ44_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU0319819.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKSLEELLEERYQRFRKY"
     gene            complement(26473..27339)
                     /locus_tag="VUZ44_000876"
     CDS             complement(26473..27339)
                     /locus_tag="VUZ44_000876"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU0319820.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(27376..28743)
                     /gene="accC"
                     /locus_tag="VUZ44_000877"
     CDS             complement(27376..28743)
                     /gene="accC"
                     /locus_tag="VUZ44_000877"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU0319821.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(28755..29177)
                     /gene="fabZ"
                     /locus_tag="VUZ44_000878"
     CDS             complement(28755..29177)
                     /gene="fabZ"
                     /locus_tag="VUZ44_000878"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU0319822.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(29174..29659)
                     /locus_tag="VUZ44_000879"
     CDS             complement(29174..29659)
                     /locus_tag="VUZ44_000879"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU0319823.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(29662..30897)
                     /gene="fabF"
                     /locus_tag="VUZ44_000880"
     CDS             complement(29662..30897)
                     /gene="fabF"
                     /locus_tag="VUZ44_000880"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU0319824.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(30919..31650)
                     /gene="fabG"
                     /locus_tag="VUZ44_000881"
     CDS             complement(30919..31650)
                     /gene="fabG"
                     /locus_tag="VUZ44_000881"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU0319825.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQVGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(31684..32604)
                     /gene="fabD"
                     /locus_tag="VUZ44_000882"
     CDS             complement(31684..32604)
                     /gene="fabD"
                     /locus_tag="VUZ44_000882"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU0319826.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(32597..33571)
                     /gene="fabK"
                     /locus_tag="VUZ44_000883"
     CDS             complement(32597..33571)
                     /gene="fabK"
                     /locus_tag="VUZ44_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU0319827.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(33690..33914)
                     /locus_tag="VUZ44_000884"
     CDS             complement(33690..33914)
                     /locus_tag="VUZ44_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU0319828.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQEK"
     gene            complement(33974..34948)
                     /locus_tag="VUZ44_000885"
     CDS             complement(33974..34948)
                     /locus_tag="VUZ44_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU0319829.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(34948..35382)
                     /locus_tag="VUZ44_000886"
     CDS             complement(34948..35382)
                     /locus_tag="VUZ44_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU0319830.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(35476..36261)
                     /locus_tag="VUZ44_000887"
     CDS             complement(35476..36261)
                     /locus_tag="VUZ44_000887"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU0319831.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            36631..37995
                     /locus_tag="VUZ44_000888"
     CDS             36631..37995
                     /locus_tag="VUZ44_000888"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU0319832.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            37998..38369
                     /locus_tag="VUZ44_000889"
     CDS             37998..38369
                     /locus_tag="VUZ44_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU0319833.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            38583..39857
                     /gene="serS"
                     /locus_tag="VUZ44_000890"
     CDS             38583..39857
                     /gene="serS"
                     /locus_tag="VUZ44_000890"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU0319834.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(39882..40781)
                     /locus_tag="VUZ44_000891"
     CDS             complement(39882..40781)
                     /locus_tag="VUZ44_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU0319835.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDMLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPERRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(40891..41439)
                     /locus_tag="VUZ44_000892"
     CDS             complement(40891..41439)
                     /locus_tag="VUZ44_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU0319836.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(41657..42979)
                     /locus_tag="VUZ44_000893"
     CDS             complement(41657..42979)
                     /locus_tag="VUZ44_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU0319837.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLVIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(43070..43158)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(43322..45658)
                     /locus_tag="VUZ44_000894"
     CDS             complement(43322..45658)
                     /locus_tag="VUZ44_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU0319838.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(45762..46310)
                     /locus_tag="VUZ44_000895"
     CDS             complement(45762..46310)
                     /locus_tag="VUZ44_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU0319839.1"
                     /translation="MISLLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(46307..46609)
                     /gene="zapA"
                     /locus_tag="VUZ44_000896"
     CDS             complement(46307..46609)
                     /gene="zapA"
                     /locus_tag="VUZ44_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU0319840.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSTDDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            46696..47577
                     /locus_tag="VUZ44_000897"
     CDS             46696..47577
                     /locus_tag="VUZ44_000897"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU0319841.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            47581..48195
                     /gene="lepB"
                     /locus_tag="VUZ44_000898"
     CDS             47581..48195
                     /gene="lepB"
                     /locus_tag="VUZ44_000898"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU0319842.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            48275..48397
                     /locus_tag="VUZ44_000899"
     CDS             48275..48397
                     /locus_tag="VUZ44_000899"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEU0319843.1"
                     /translation="MKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVADGS"
     gene            48474..50840
                     /locus_tag="VUZ44_000900"
     CDS             48474..50840
                     /locus_tag="VUZ44_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU0319844.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEVPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(50888..52171)
                     /locus_tag="VUZ44_000901"
     CDS             complement(50888..52171)
                     /locus_tag="VUZ44_000901"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU0319845.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        15436 a        11917 c         9877 g        15054 t
ORIGIN      
        1 gaaaagtata aaaaggtgct aggcatgttg atttttcctt tgttaaatga tttgtcaaga
       61 aaaatcatcc atattgacat ggatgccttt tttgctgcag tggaaatcag ggataatcct
      121 aaactcagag gaaaacctgt cattattgga agcaaccctc ggcaaacagg tggacgggga
      181 gtcgtttcta cctgtagtta tgaggcaaga gcttttggtg tccattctgc catgagttcc
      241 aaggaagctt atgaacgttg tccccaggct gtctttatct cagggaatta tgagaaatac
      301 aagtctgtgg gactccagat tcgagctatt tttaagcgct atacagattt gattgaaccc
      361 atgagtattg acgaagccta tttggatgtg acagaaaata aactcggtat caagtcagcg
      421 gtcaaaattg ctcgcctcat tcaaaaagat atctggcaag aactccatct aactgcttct
      481 gccggtattt cctataacaa gttcttagct aaaatggcga gtgattatca aaaacctcat
      541 ggtttgacag tgattctacc tgaacaggct gaggattttc tcaaacaaat ggatatttcc
      601 aaatttcatg gagtaggaaa aaagacagta gaacgtcttc atcaaatggg cgtttttact
      661 ggtgctgatt tacttgaagt tcctgaggtg accctaatag accgttttgg tagactaggc
      721 tatgatctgt atcgaaaggc tcgtggcatt cacaactctc cagtcaaatc caatcgcatc
      781 cgtaaatcaa tcggcaagga gaaaacctac gggaagattc tccgtgctga ggaagatatc
      841 aaaaaagagc tgactcttct atcagaaaaa gtcgctctca atctacatca acaagaaaaa
      901 gctggaaaaa ttgtcatttt gaaaatccgc tacgaggact tttcaactct taccaaacga
      961 aaaagtcttg ctcaaaaaac acaagatgct agtcagataa gccaaatagc cctgcaactc
     1021 tatgaagaat taagtgagaa agaaagaggt gtccgcctat tggggattac catgactgga
     1081 ttttaaagct caatgaaaat caaagagcaa actaggaggc tagccgcagg ctgctcaaaa
     1141 cactgttttg aggttgcaga taaagctgac gcggtttgaa gagattttct aagagtataa
     1201 aaccttgaag agttgcccct tcaaggtttt tcttatacaa ataaacggac aaaactgtaa
     1261 agtagcaaaa cactaccaag cacgatacgg tatttaccaa aaagggtgaa gtcgtgtttt
     1321 ttcacatagc tggtcaagaa gcgaatagcc accatgctga ccgcaaaagc tactcccatc
     1381 gcgaccaaga gcaaaaacaa ttgcccaaag ctcaagagtt ctccggcttt cacaaatttg
     1441 aaaatcttta aggcactagc tccaaacata acaggaatcc caagatagaa ggtaaattct
     1501 gtcacaactg aacgactggt tccatttaac aaaccaccga caatcgttgc acctgaacgg
     1561 ctagtccctg gtaaaagagc aagaacttgg aagagtccga tatagaaagc ggtcgtataa
     1621 ggaagcttgt ccaactctgt tacacttggc tcgatagcac gcgctttatt gcgcttttcc
     1681 aaatagatga aggcaatccc gtagataatc aacatgagag caactgaaac catgttatgg
     1741 aagtgggtat caaaccaatc atcaaattta aagacaccaa gtaaaggtaa agtagcaatc
     1801 aagaccttca accatagtct ccaagtctta cgaacttcct gtttgtcctt agtcggttta
     1861 aaaggattga gcttgttaaa ataaatcacc ataactgcta aaatagcacc aagctgaatc
     1921 acgacattaa acatggacat aaaggcttca ttttgatttt ggtattggat aaactcctct
     1981 gctaaaatca agtgacctgt actggaaatc ggcaaccatt ccgtaattcc ttcaacaatc
     2041 ccgaagaaga tagattttaa aatttcaata agatacatat atttctcctt atattatatt
     2101 taacgcagtt agctactgcc aaagcccaag tggtatactt ggaataagcc actgtggatt
     2161 agttcatttc ctccaatcgc ttgacgattt ccgaaagggt ctaaccacag ctttttgttt
     2221 caattggtaa tgagtttgat aacgcataga cgttttatct cgtctaaggt aacaaggcaa
     2281 aaagttcgtg gataaccaag tagacttgaa atactatatc tggaggtact cccatgcttt
     2341 atgtgggcat tgatgtcgct aaaaataaac acgatgttac agccttgaat gttccaggaa
     2401 aaactgttct taaaccactc actttttcaa ataataaagc tggttttgaa ctcttagatc
     2461 tgtcttttcg acagctcaac caagactgtc tcatcgctct tgaagatact ggacattatg
     2521 cctttaatct actgaacttc ctgcatgaac aaggatataa agtttacacc tacactcctt
     2581 tgctcatcaa ggaatttgcc aaatcattat cacttcgcaa gactaaaacg gataagaaag
     2641 acgctcatgg catcgctctt aaacttcttt ctgaccccaa tcgtgaacaa tttcaacacg
     2701 ataatcggca agtagaacta aaaatactgg ctagacatat tcatcgtctc aagaaaaaac
     2761 agtctgattg gaaagtacaa tacactcgtt gtcttgatat catctttcct gagttggata
     2821 aaatcgttgg aaagcattca gaatatacct accaactctt gacatgctac cctaatcctc
     2881 agaaaaggct tgaggcagga tttgataagc tgatagaaat taagcgattg accgcttcta
     2941 aaattcagga tatcctctca gtcgcacctc gttctatcgg aacaacatct cctgctcgtg
     3001 aattcgaaat catcgaaatc atcaaacatt acaagaggct cattgacaag gcggaaacat
     3061 gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggttact gggattgggg
     3121 gtcgtttagg ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt gataatcctg
     3181 ctcaattaca agctttcgct ggactggatt cttctattta tcagtcaggt cagattgatt
     3241 tagctggaag aatgatcaaa cggggttccc ctcatctgcg gtgggcactc atacaagctg
     3301 ccaaagcatg cgctcgcttt tcacctgctt ttaaggccta tcttaagact aagttagaat
     3361 aaggaaaaca ttacaatgta gccatcatcc accttgcaaa aaaacttatc cgaaccctgt
     3421 tttatatcct aaaaaagagc tgccatttga cgaacaaaaa gtgatgtaat ttctgaaatt
     3481 aacacaggat tacctttgaa aaaatggact ttttcaatag ctttttgccg tgctctaaaa
     3541 tcatcgccaa atcatcaaat tgaaataaga aatagtttag ataaaactat tgacttttct
     3601 tatagtttgt ctttcttcta tcttccatta tatcatactt tttcagtcta tggtagctct
     3661 ctttaaaagg ctccgatact gccgccacct ccgcctccag agaagccacc accagaactt
     3721 ccacttccag aagatacaga gtaagtactt gctgtatttg cgacactagc ataatggctc
     3781 atttgcgcgc ttgaatgata aaacatactg tgccagccat aagctacata gagattgata
     3841 tctggatttt caacttgaat ctgatgaacc ttcatcaaat gactaacctt gtccgcatag
     3901 ccaaataagg ttgcatagac caagagacga ttccaaacaa caatactttc caattcagcc
     3961 ttatccagtc gtgcaatctc acgtaacata ttttcaaaac tggtccagag atagtagacc
     4021 tcagctcccg cttcatttag aacaccatca cgattatcta gtcgaagctt ccaataatag
     4081 aaaacagaca aaactaaccc tagaaaacca agtattggca aagggaggta aagatagcca
     4141 tgaacgtcta aactgtacaa gaacaaacca aatccgataa ataggggcaa gatagtcaag
     4201 acacccatac ccacttgcaa agccttttcc aaaccagtta aaggacgata gtaatctggg
     4261 agtccccaga agacaactcg ctttctcact ccttcttgca tctcttttaa tactgcttcg
     4321 aaagaagatt tgagctgaat ccctcttgct tgaatccgtt tctcatcagc agctttagct
     4381 ccgcgataaa ggctgtcaga taccttgtaa tccgcaaaca aattggaaag agtggcttct
     4441 tttttgcctg aaaaggctag atttagacag tctctctcaa atcttgacaa accatcttct
     4501 ttcaccaatc tcaagccaac tgcatctcct tctgaaataa tagaaacatt cccacggtcc
     4561 atcacatcta gcaaggtagc ttgaataagt tggtcaaaag tgaatttgcc agcccccttg
     4621 actaagggac tcacttcctc caaggaggtc gagtagacag cctctgataa aaccataggc
     4681 tctaattcca ttggtggttc atagagacga tgatttttgg catatttgac tgaaggagtg
     4741 gtctttcttc tataaataaa atagaagcag acactcaata acaaggagat agaaaggatc
     4801 gaagggagga cccaagtaac aagttgttta ctctgatctt tttctctaac aatcgagtct
     4861 tctatcttat taaactcttc taaacgattc cctttcaatc cctgatccct agcgctagca
     4921 aaatcggtcc gaggccagta ggcatgcaac tcaactccac gcttagccgg aagattgtct
     4981 aaacggatag tataatcaag gttactcttt tcaatcgttc cctctctaaa aagtttccct
     5041 gtatggaaaa agagtttttc agcccccttg tctcccctta catgaaattc aaacttttca
     5101 atagactctg aactatctgt cagaggttgc caatttaatt cagcgatatc atcataaaga
     5161 aaaagtaaat tttttaagtt ccagacgagg tcaacttcaa ctatgtcgcc ctcctgacct
     5221 ggattataga ctctcacagt ataaccatcc gcttcttctg ttacttcgct agtcacatct
     5281 gctagttctg caccgttttt cgcggcctga acctttggat gagggtcaat gtcaaacccg
     5341 ctaggcatct taccagcacg tccaagtccc acgatttgtc ccttaaagtc ctcctcaaac
     5401 tggtaaacta tcttctgtct aaactctgcc gtattatctg catgaatata caaatcccct
     5461 tgataagagt ttatcttgaa atcaatggca aaaacagaga gtggaagaag gcaaaacaag
     5521 cctaacacca gtaagaaaaa agtttttttc atcaactaag cccccttttt atctttctta
     5581 tcattatagc attttttcgt aagtaaaggc ttacttatgt tgaaaaatta cgcatttttc
     5641 gataaaatag gagacagtta ttttttaata gatcagaata ggagaaatca tgagaaaaat
     5701 atacttatct attttcacaa gtctcttgct gatgctagga cttgtcaatg ttgctcaagc
     5761 cgatgaatat ttacgcatcg ggatggaagc agcatatgct ccctttaact ggacccagga
     5821 tgatgatagc aacggagctg tcaaaatcga tgggaccaat cagtatgcca acggatacga
     5881 tgttcaaatc gccaagaaaa tcgctaagga cttaggtaaa gaacctttgg ttgttaaaac
     5941 caagtgggaa ggtctagtcc ctgcccttac ttctggtaag attgacatga ttatcgcagg
     6001 tatgagtcca actgcagaac gcaaacaaga aattgccttt tcgagcagtt actacactag
     6061 cgaaccagtt ttgcttgtca aaaaagattc tgcctacgca agtgctaaat ctttggatga
     6121 ctttaacggt gcaaaaatca cttctcaaca aggggtctac ctctacgact tgattgcaca
     6181 aatcccaggt gctaaaaaag aaacagccat gggagacttc gctcaaatgc gccaagctct
     6241 tgaggctggt gtcattgatg cttatgtttc tgaacgtcca gaagcactga ctgctgaagc
     6301 tgcgaactct aagttcaaga tgattcaagt agaacctggt ttcaaaactg gggaagaaga
     6361 tacagctatc gctatcgggc ttcgtaaaaa tgacaatcgt attagccaaa tcaatgccag
     6421 cattgaaacc atttcaaaag atgaccaagt tgccttgatg gatcgtatga tcaaggaaca
     6481 acctgccgaa gctacaacaa ctgaagagac tagcagtagt ttctttagcc aagtcgctaa
     6541 aattctttct gaaaactggc aacaactctt gcgtggtgct ggtatcactc ttttaatctc
     6601 tatcgtcgga accatcatag gtctcattat tggacttgcc attggtgtct tccgtactgc
     6661 tcctctctct gaaaacaaag ccatttatgg ccttcaaaaa ctagtcggct gggttctcaa
     6721 tgtctacatt gaaattttcc gtggtacgcc aatgattgtt caatcgatgg ttatctacta
     6781 tggaactgcc caagctttcg ggatcaacct tgaccgtaca ctagctgcta tcttcatcgt
     6841 ttcaatcaat accggtgcct acatgactga aatcgtccgt ggtggtatcc tagcagttga
     6901 caagggacaa tttgaagctg cgactgctct tggtatgacc cataaccaga ccatgcgtaa
     6961 gattgtccta cctcaggtag tccgtaacat cctacctgca actggtaatg aatttgtcat
     7021 caatatcaaa gatacatctg tattgaacgt tatctctgtt gtcgaacttt atttctcagg
     7081 aaataccgtg gcaacacaaa cctatcaata cttccagaca tttacaatca tcgccgtgat
     7141 ttactttgtc ctcaccttca ccgtaacacg tatcctacgc tttatcgagc gcagaatgga
     7201 catggatacc tacactacag gtgctaacca aatgcaaacg gaggatttga aataatgaca
     7261 caagcaatcc ttgaaattaa acacctcaaa aaatcctatg gacaaaacga agtgctaaaa
     7321 gacatttcac tcactgtcca caagggagag gtcatctcta tcatcggaag ctctggaagc
     7381 ggaaaatcga ccttcctacg ctccattaac ctacttgaaa caccaactga tggacaaatc
     7441 ctttatcatg gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata ccgtgaaaag
     7501 ttggggatgg ttttccaatc ctttaacctc tttgaaaatc tcaatgttct tgaaaacaca
     7561 atcgtcgctc agacaactgt cctaaaacgc gaacgcacag aagctgaaaa gattgccaaa
     7621 gaaaacctgg aaaaggtcgg catgggagaa cgctactggc aagccaaacc aaaacaactc
     7681 tcaggtggtc aaaaacaacg tgtggccatc gctcgtgccc tctccatgaa tccggacgcc
     7741 attctctttg atgaaccaac atcagctctc gatccagaaa tggttggaga agtcctcaaa
     7801 atcatgcagg acctggctca ggaaggcttg accatgattg tcgtaaccca tgaaatggaa
     7861 tttgcccgtg atgtctctca ccgtgttatc tttatggata agggcgtgat cgctgaagaa
     7921 ggtaaaccag aagacctctt caccaatcct aaagaagacc gaacaaaaga gttccttcaa
     7981 cgctatctca aataaaaaga aaaggctgca tcaaccgtgc agtctttttg ctgtcctcaa
     8041 aatgaaaagg cagattctct atctctacta cttgaaggtc aagaatccgc cgttatccaa
     8101 agattaatct tcaaattttt cataattttt ttcatagaaa tcaattaggc ctagggctgt
     8161 ttcaaatgaa atatttttta cttttgcacg accctgcgcc agagcaatga tagacatttc
     8221 acgcgcattc gtttctttag agatacggta gcctgtgatt ttcttatcac gaacccagcc
     8281 aacaactgat tctacttttt caaagtttga cttagccatg tttttctcct attttcttct
     8341 ttataatatt taattgtata cgtttttact acttttgtca ataaaaaaaa catatattca
     8401 acgaaaataa ttagttcaga attttcttac ttccttttta aatccgataa tatataggtt
     8461 ttgctagcct ctacaccata aatatttgct aataaaacta ctgtattatt accctcttaa
     8521 ggtgcgaaat tattcaagtt cttaaaaaat gcttctctat ttccgtaaga tagcttattt
     8581 cttcgattta agaactgaag atgatagttc taacctttag aaatccaagc cttcactagc
     8641 tcaaaaactc ctatctttct tcctcaataa atcatctgag agataggtat tccttatatc
     8701 cttcaaattc atcactcctt tggatattga ggtgctagcc tagaagcaga cacccgatta
     8761 tctaaaccat ccttaataga gatgacaaga cagataagct cagttaatta cttatatatc
     8821 tttttaatat ggtatatttg tcaacaaaaa gaaatcaaat cataccttat actcaatgaa
     8881 aatcaaagag caaactagga agctagccgc aagttgctca aaacactgtt ttgaggttgc
     8941 agatagagct aacgtggttt gaagagattt tcgaagagta ttaaagacag tgtgactatg
     9001 cttgtcaata gataggaaat caaaatgaag gatggaaatc tgagccaaac atcataagtg
     9061 ctataatgaa cagaagtaag aattgcacga taagttttct aaaaccatag gaatcgtccc
     9121 ctttcttcat cttcattata gcacatatac atcagttgta caaataatat gatatttttt
     9181 tattagtcct cagacaagca tattataaag cgtttcatta ccatttaagt taatataagc
     9241 tggatcaaaa ccttccattc tacgaatcaa acctgcataa tcatgcttat ctgctaaagc
     9301 gatcccaatt aatactgggc ctgttccctt gctagctcgt ttgatatact caaaacgtgt
     9361 gatatcatca tttggcccca ggatatcatt tacaaactca cgcaaagctc ctggacgttg
     9421 tgggaaattg accacaaagt aatgtttgat accatcataa atcaaggcac gctcttccat
     9481 ttctggcata cggttgatat cattatttcc tccagaaatg atacaacaaa tggttttccc
     9541 cttaatatat tcagctaaaa cctctaaaga ggcgatacta gctgctccag caggttctgc
     9601 gactatccct tgcttagagt aaaggtcaat caaggtttca gaaatcaatc cctcatcgac
     9661 acctaccaaa gtttgaatat gttgacgagt tgcttcatag gtcaactgac ctaccttttg
     9721 cacagcaatc ccatccgcaa atttatcaat ttccttgagt ttgactggac ctccagcctc
     9781 aaaggcagct ttcatggaac gcgctccatt cgcctctact ccgataacct caatctctgg
     9841 acttgtttcc ttgatatagg tagaaacccc ggcaatgaga ccgccaccac caacaggaac
     9901 caagacagca tcaaaatcaa tcgattcttt tcgagcttct tctaaaatct cataagcaac
     9961 tgttccttga cctgcttgaa catgagcatc atcaaaagga tcaataaagg tacgattttc
    10021 agagactgta aattcttgag ctgctttggc tgaggcatca aaggtatctc caactagttt
    10081 aatagttaca aaatccccac caaaaaagcg aacctgacca atcttttgtt gtggcgtagt
    10141 aatgggcata aagatagtag caggaatttt catttcatta caagtatagg ctactccctg
    10201 cgcatgattt cccgcagaag cgcaaactac cccacgttca cgttcttcct tgctgagctg
    10261 ggaaatggca taataggcac cacgaatttt aaaggagcga acacgctggg cattttcttt
    10321 tttcaaataa atcttagcac catacttctc cgataaataa tgatcgtaat ccagtggagt
    10381 attcacaacc acaccgttca agaccttgtg agccttgatt atatcttttg aacttaacat
    10441 ataaaacctc tttttctata aaaaacagtc actaatgact gttttttagt tattcatctc
    10501 cgaaaatttc agtaacactt tcatggtatt tatgagccat acgaatcgaa aactctttag
    10561 gaagttcata acgatttgtg gaaatccaat catataacca ttctaccaaa ctttcttcac
    10621 tatcattacg atggaagata aaatagttta aaatttcttt atattctaca tcattcaaat
    10681 ccaacgtgtc tacaaattga ctacgaggaa caaaattaga atctaatttt cttagttgat
    10741 ctgtcaattc tcccaattgt aaatccaact gaaaaaatag tttttgcagt tgcctatcag
    10801 tttcatcaca tcctgtcttg atagaaaaca aattggtaat attcatatga tttcaacccc
    10861 taaataagta catctaatat cccacgaata gctgaagcta aagttttcgc agtccagtca
    10921 tttaaacccg attctttcaa tccagatgca ataatttgct ctatttgata taaaccgcca
    10981 tctatcgtct catttattct gcgaagagga ccttcaatat aggataaagc ttctccgaat
    11041 ctaacagctg atttaggtcc taatgattta ccaactatat ttgttaatat tttttatttc
    11101 tcaaaatcca tttcgctata taacgagcag atttagtcgc accagctctc tcaaacggag
    11161 aatgaatttc aagaccttct tctctagcta tttgtgccaa tttgaagaat tgttcaaagg
    11221 tcatatgcaa cctaccatct tcaaaattag catcatcata aatgttaatt acagcatttt
    11281 catcatacga ccaatctgct ttattttggt ctgctagcac tattaccgac ggtgtaatta
    11341 cattatacaa ctagaaccaa taataacgat gcaatttttc tcataatctt tttcataaaa
    11401 tcatctccag cgctatatat ttctaattag ttatagattt tgaatgcatc atcgtcgttt
    11461 ttaccaacga atggcattgc tttacgcaat tctgcaccaa ctttttcaat ttcaaggtta
    11521 gctgcttgtt cacggtaagc agtcaatttt ggacgtccag ctttatagtc atttacaaag
    11581 tcatttgcaa atttaccatt ttggatgtct gccaagacag ccttcatatt ttctttaact
    11641 tgttcagtga ttacacgtgg acctgataca tagtcaccgt attcagcagt gtttgaaata
    11701 gattgacgca ttttcttgaa tccaccttcg tagatcaagt caacgatcaa tttcatttcg
    11761 tgaagaactt caaagtaagc caattctgga gcgtaacctg cttctgtcaa gacttcgaaa
    11821 cctgcttcga taagggcagt caaaccacca caaagtacag cttgttcacc aaacaaatct
    11881 tcttcagttt cttctttgta agttgtttca agaagaccta cacgagccgc tccaacacct
    11941 ttacaccagt ccatagcaat gtttttagca tttcctgttg catcttggta tactgcataa
    12001 agagctggaa caccaaatcc ttcttcgtaa gtacgacgta ccaagtgtcc tggtccttta
    12061 ggagcacaca tgaagacatc tacatccgca ggaactttga taaattcaaa gtggatgttg
    12121 aaaccatggg caaatccaac tgcgtttcca gcttccaagt ttggagcgat ttctgcttcg
    12181 tacaattctt gttgaatttc gtctggcgcc aagatcatga taacatcagc caacttagta
    12241 gcttctgcta ctgtgtaagt atcaaatcca tcttcttttg ctttatcaaa agatttacct
    12301 ggacgtacac cgataataac gtcacgacct gaatcacgca agttttgagc atgcgcatgc
    12361 ccttgtgaac cataaccgat aacggcgatt tttttaccgt caagtgctgc tactttaaca
    12421 tctttttcat attccatttg aactgtcata gcttttctct cttttctatt atttattgcc
    12481 ttttaagctg gtttaacaaa tttaagttgg atttttaatc gcgggtaaat ccagttgcac
    12541 ccgttcgagc aatattgcga ataccgtatg ggcgaatgac tcgcaatagg gcttcgctct
    12601 tttctgcatt tcccgtcatc tgaatggtaa tcgagcttgg cgctacgtct accactgttg
    12661 cacggaaagg ttgaataatc gctaaaatct cagctctctt ctcagctggc gctgacatct
    12721 taaccaaaat cacctcgcgc tccaaatgag gcttgtctgt aatatctcga atgcgaatca
    12781 catcaatctg acgattgagc tgtttgatga tttgctccac ttcatcatga gaagcaacat
    12841 caataataat agtgatacgc gatacattcg gatcttctgt tgctccaaca gagatgcttt
    12901 caatattaac ctgacgacga gataggacac ctgtaaagcg attgaggact cctgaacgat
    12961 tttgtagttt tgctgttaac attctacgca tggaactgca cccccaacat ctcatgatta
    13021 ctcttaccag ccggtaccat tggtaacacc tgttccttac gagaaatatc tacctcaatt
    13081 agcataggaa catcctcagt gatgacttca aggtcttgag ccaaggtctc aggattgtca
    13141 aacttatagt ttttaatacc ataagcctgc gccatcaatt ggaaatcagg aagggtatca
    13201 aagaccgact ctgatgttct gccttcatag aaggattcct gccactggcg aaccattccg
    13261 agtgaatgat tgttcagcat aaccaccttg attggcacct tgtaaatatt caaaatagcc
    13321 aactcctggt tggtcatttg gaaaccacca tccccaacaa acaagactac ttccttatct
    13381 gggttagcaa ttttagcacc gattgctgct ggaattccaa agcccattgt tcccaaacca
    13441 cctgaagtca ctaactgacg ttcattttgg tagggataat actgagctgt ccacatttgg
    13501 tgttgaccaa cgtctgttac cacaatggca tctccattcg tcaattcacc aattcgttca
    13561 ataactgctt gcggttgaac cacacgctct ttcttgtcat acgaacgaac acgattcttg
    13621 tctttagtga ctttctcaat ccacttttca gtattgttgt gaactgttgg ttctgctagc
    13681 aacatttgca aggccttctt agcatctcca actacaggaa tgtctgcact gataatcttg
    13741 ccaatctcag ctgggtcaat atcaatgtgg gcaaccttag cattcttagc gaaagtctta
    13801 ggattccccg tcaaacggtc atcgaaacga gaaccaatac taatcataaa gtccgcttcc
    13861 gtcatggcaa tatttgctgc gaatgacccg tgcatgcctc ccattccaag aaagagtggg
    13921 tgactcgttg caatcgttcc ttgtcccaaa agactggtta ccactggaat ttgatagcgt
    13981 tctgcaaatt catttagttc cgtagcagcc tcagcataac taattccacc accagctaac
    14041 aagactggct ttttagcctt ggacaattgc ttcaagattt tcttgatttg catatcattc
    14101 ggctcaagag tcggctgata acttggtaaa ttcacttctg gtgaataaat gaagtctgtt
    14161 tctaaagcag atatgtcttt tggtaggtca attacaactg gccctggacg gcctgtagtt
    14221 gcgatatgga cagcttccgt aatgatacgc ggaatatcag ctgtctcacg aacttggtaa
    14281 ttgtacttag tgattggcat ggtaattcct acgatgtctg cctcctgaaa ggcatccttc
    14341 ccaatccctg ctcgcgccac ctgacctgta aagaccaaaa ggggaacgct atcgctcata
    14401 gcatccgcaa tccctgtaat ggcatttgtt gctcctggtc cactagtgac gacggcaaca
    14461 cccaactttc cagttgattt ggcatagcct tcagcttcat gcaaacaacc ttgctcatgg
    14521 cgccctagaa tgtggcgaat gcctttaaaa ttatatatcg catcataaaa aggcaaaacc
    14581 gcaccaccag gataaccaaa gatggtatca actcctaaat cacgaagtgt ttccaaaact
    14641 aggtccgacc ccgtcttagg agattctaaa ctgattttct ccattattcc cctttctttc
    14701 ctcttaaaaa taacttgtta ctatcatacc attttttcaa aatttttcaa gataaaagaa
    14761 gaaattttct gaattttcta ttttaacgtt tatttatgaa tgttattttt gtttttatta
    14821 aaaagatacc gatttcattt actaaaaaga aaaaagaact gatttctcag tccttcatta
    14881 atcttattcc acactaaata ggtatgggta aacaggttgt tgaccttggt gaatctcgac
    14941 ttcaacgtct tcgaattctt ctacgatttc ttgagcgatt tcattggcaa gttcttcgct
    15001 tccgtcttca ccgacataga aggttacgat ttcactatct tcatccaaca tatgtttcaa
    15061 ggtttcagtc aatgtttggt gcatatcagg gtttgacaca agaatttttc catccaccat
    15121 acctagatta tcgttttcat ggatttctaa gccatcgatc gttgtatcac gcacggctgt
    15181 tgtgacgctt ccgctaacga catcgctaag agcagctgtc atacgctctt ggttttcttc
    15241 aatggacttg cttggatcaa aggcaagaag acttgtcata ccttgaggaa gagtgcgagc
    15301 ctctaccact actgctggtt gctccaaaac ttctgccgca gattgagctg ccatgaagat
    15361 gttcttgttg tttggtaaga agatgatgtt acgggcattg acctgttcaa cagccttgat
    15421 aaagtcttct gttgaagggt tcatggtttg accgccttcg ataacataat ccacgccttg
    15481 agaacagaag atatctgcta gacctttacc agccaccaca gcaatcaaag catactcttt
    15541 ttcttcagcc gacttgataa cttgagtagc ttctttctca acctgtgctt cgtgttggtt
    15601 acgcatattg tcaactttta ccttgaccaa gctaccatat ttgagacctt cttgcataac
    15661 aagtcctgga tcttctgtat gaacatggac tttgacaatt tcatcatcgt taacaacgag
    15721 gagagaatcc ccaagctcat ccaagtagtt acggaattca tcgtagtcaa aatctttagc
    15781 ataggttgga ccttgcttaa gagctaccat gatttcagta cagtaaccaa acgtgatgtc
    15841 ctcagttgct acgtgaccag ctacagactt atgatgctct acattgatca tctcactcat
    15901 gttggcagga gtcgctacaa agtcctcaga tgcaatatat tcgccagtaa gggctgaaag
    15961 gaaaccttcg tagatgaaga ccaatccttg accacctgag tccacaacgc caacttcttt
    16021 caatactgga agcatgtctg gtgttttagc tagagctgtt ttagcacctt ccaaggctgc
    16081 gcgcatgact tcaacagtgt catctgtttg ctcagctttt ttcttagcac cgatagcagc
    16141 tccacgagaa actgtcaaaa tcgttccttc aacaggtttc atcactgcct tataggcaac
    16201 ttccacacct gattggaagg ccagagccaa gtcttgacct gttaactcgt ctttatcctt
    16261 gatagcttgg gaaaatccac ggaaaagctg agacgtaatc actcctgagt tcccacgcgc
    16321 acccatcaaa agccctttgg caagaatgct cgctacttct ccaactgtag aagctggctt
    16381 gtctgcaact tctttagcac cattttcaat ggtcattccc atatttgtcc cagtatctcc
    16441 atctggaact ggaaagacgt ttaatgaatt gacatattca gcttgcttat tcaagcgagt
    16501 tgatgcagcc tgcaccattt cttgaaataa gctagtagta atttttgaca cggttattct
    16561 cctacaactt tgatattttg aatgtagaca tttacagtct gagcagtaat tccaagctgg
    16621 ttttccaagc taaaggcaac acgctcttga atgttttttg acacttcact aatctttgtt
    16681 ccgtagctta acacggtata tacatcaact gcaatactgc catcttcggc tgcctttacg
    16741 acgacacctt tagaataatt ttccttacct agcagggctt ggaaattatc tttgagggca
    16801 tttttactag ccataccgac cacaccaaaa atctcagttg ctgctccacc tacgacggtt
    16861 gcaatcactt catctgttag ttcgatttga ccatcttttg tattaatttt tacagtcatc
    16921 ctttttacct caactagttg atactctatt ttatcatatt tcagcccaag tgtaaaagca
    16981 gaatgatgta tcagcggata tttactctat ttttcaaacg atgttatacc cacaataaaa
    17041 gaaaaaagac cctaaggtct cctttgcttt tattattaaa cgcgttcaac tttacctgat
    17101 ttcaaagcac gagctgaagc ccaaactttt ttaggtttac catcgataag aacagtaact
    17161 ttttgaaggt ttggttttac ggcacgtttt gtttggttca tcgcgtgtga acggttgttt
    17221 cctgatacag tcttacgacc tgtaaagtaa catactttag ccattgtgtt ttcctcctat
    17281 tagatctaat atagcggatg tgctagcacc acataccgta ctatgttatc acactttctt
    17341 gttttttgca agggaattgg aagatttttt atttgtgtct taaatcaggt cttgcgtgac
    17401 attttctgct ctccacatgc catcgttgat taacagaaca ccagaattaa aattatgtgt
    17461 ataaaaatca tctctaactg cagctaaggg tatagccgtc aagtccaaat cccacagctc
    17521 atctatcgat tttcttacaa caatatctga atccaaatac agtacacgag actcgcttac
    17581 atactttgga ataaaatacc taaaaaagcc gcatatgaaa gtccctcaaa ggggagacga
    17641 taacctttca gaatattact gtcaatctaa acattcacaa tctcactatt caaagtctct
    17701 agtctttttt ccatcaattg gaaccattct cgcggaaggt catcattaaa aacataaaac
    17761 ttaagattat aatgatgaac acaaagagat tttattgttg tttcaacttt atccatataa
    17821 gcattatctg cacctaagac aatcgctttt ttctcttctt tcacttttta tctcatttct
    17881 ttttattccc atcatatgtt tctacgtaac cattattttc gcctattcgt tcgtaaaacc
    17941 ataccagtgg agattttaga tgaagtccca ttacggttta caatttttac attacgacac
    18001 ggagttttac aaatcgattt catttgccaa acgtagttag tgaggcagtt agctagttcg
    18061 ccaaatagcg actagcgtcc aacaatttgg aactttagtt ccaattgttg gtactgagtc
    18121 acatcttctc ctctaactct acgtctggat acttgtcagc aaaccagcgg agggcaaagt
    18181 cattttcaaa gagaaagact ggttggtcaa aacggtcttt ggctaagata ttgcgacttg
    18241 acgacatccg ttcatccaag tcctcaggct tgatccaacg aacggtcttt ttacccattg
    18301 ggttcataac tacttctgca ttgtactcgc cttccatgcg gtgtttaaag acttcaaact
    18361 ggagttgacc tacagcgcct agcatgtact cacctgtttg gtaattctta taaagctgaa
    18421 cggctccttc ttgcaccaat tgctcaatcc ccttgtggaa ggatttttgc ttcataacat
    18481 tcttagcaga aactttcatg aaaatttcag gagtaaaggt tggcagtggt tcaaattcaa
    18541 acttgttttt accaactgtc aaggtatccc caacttgata agtaccggta tcgtaaaccc
    18601 cgataatatc acctgccacg gcattgatca cattctcacg actttccgcc ataaactgag
    18661 taacattaga cagtttagcc cccttaccag tacgagggag attgacactc atgccgcgct
    18721 caaattcgcc agatacgata cggacaaagg caatacggtc acggtgacga gggtccatgt
    18781 tggcttggat tttaaagaca aagcctgaga aatccttgtc ataaggatcc acaatttcac
    18841 cgtctgtttt cttgtgacca tgtggttctg gagcaaactt gaggaaggtt tcaaggaagg
    18901 tctgcacacc aaagtttgtc agggctgaac cgaaaaagac aggcgtcaat tctccagcca
    18961 gaatagcttc ctctgaaaac tcattcccgg cttcatttaa aagctcaata tcatccttga
    19021 cttgctcgta gaaaggattg ctaccaaaaa gtttgtcccc atcttctaga ctggcaaaac
    19081 gctcatcccc tttataaagc tctaaacgtt ggttatagag gtcatacaag ccctcaaagg
    19141 ctttccccat cccgataggc cagttcatag ggtagctagc aatgcccaag atttcttcca
    19201 attcttgcaa gagatccaaa ggctcacgac cgtcacggtc cagcttgttc ataaaggtaa
    19261 agactggaat gccacgatgt ttcacaacct caaacaattt cttggtttga gcctcgatcc
    19321 ccttggcaga gtccacgacc atgaccgcag catccaccgc catcaaggta cgataggtat
    19381 cttctgagaa gtcctcgtgc cctggcgtgt ctaagatatt cacgcgcttg ccgtcgtagt
    19441 caaattgcat aacagatgaa gtaacagaaa tcccacgttg cttctcgata tccatccaat
    19501 cagatttagc aaaagtccct gttttcttcc cttttaccgt accagcctca cgaatttcac
    19561 ccccaaagta gagtaactgc tcagtgatgg ttgttttccc cgcgtccggg tgggagataa
    19621 tggcaaaggt acgacgtttc ttaatttctt cttgaatatt cataagttct ctttctttga
    19681 ttctctattt ttcttgtttc aatagctgag aatgattttt acattggatt ttaccattcc
    19741 tttcaacact ccattatatc ggattttagc atttttttca atttctattt cttttcactt
    19801 ccccctccct tatttatagg aaaatatggt aaaatagaac agactaaaaa tcatcatttc
    19861 acgaaaggat gcaagatgaa aattacgcaa gaagaggtaa cacacgttgc caatctttca
    19921 aaattaagat tctctgaaaa agaaactgct gcctttgcga ccaccttgtc taagattgtt
    19981 gacatggttg aattgctggg cgaagttgac acaactggtg tcgcacctac tacgactatg
    20041 gctgaccgca agactgtact ccgccctgat gtggccgaag aaggaacaaa ccgtgatcgc
    20101 ttgtttaaaa acgtacctga acaagacaac tactatatca aggtgccagc tatcctagac
    20161 gatggaggag atgcctaatg acttttaaca ataaaactat tgaagagttg cacaatctcc
    20221 ttgtctctaa ggaaatttct gcaacagaat tgacccaagc aacacttgaa aatatcaagt
    20281 ctcgtgagga agccctcaac tcatttgtca ccatcgctga ggagcaagct cttgttcaag
    20341 ctaaagccat tgatgaagct ggaattgatg ctgacaatgt cctttcagga attccacttg
    20401 ctgttaagga taacatctct acagacggta ttctcacaac tgctgcctca aaaatgctct
    20461 acaactatga gccaatcttt gatgcgacag ctgttgccaa tgcaaaaacc aagggcatga
    20521 ttgtcgttgg aaagaccaac atggacgaat ttgctatggg gggttcaggt gaaacttcac
    20581 actacggagc aactaaaaac gcttgggacc acagcaaggt tcctggtggg tcatcaagtg
    20641 gttctgccgc agctgtagcc tcaggacaag ttcgcttgtc acttggttct gatactggtg
    20701 gttccatccg ccaacctgct accttcaacg gaatcgttgg tctcaaacca acctacggaa
    20761 cagtttcacg tttcggtctc attgcctttg gtagctcatt agaccagatt ggaccttttg
    20821 ctcctactgt taaggaaaat gccctcttgc tcaacgctat tgccagcgaa gatgctaaag
    20881 actctacttc tgctcctgtc cgcatcgccg actttacttc aaaaatcggc caagacatca
    20941 agggtatgaa aatcgctttg cctaaggaat acctcggtga aggaattaac ccagaggtta
    21001 aggaaaccat tctaaatgcc gctaaacact ttgaaaaatt gggtgctatt gtcgaagaag
    21061 tcagccttcc tcactctaaa tacggagttg ccgtatacta catcatcgct tcatcagaag
    21121 cttcatcaaa cttgcaacgc ttcgacggta tccgttacgg ctatcgcgca gaagatgcaa
    21181 ccaaccttga tgaaatctat gtaaacagcc gaagccaagg ttttggtgaa gaggtaaaac
    21241 gtcgtatcat gctgggtact ttcagtcttt catcaggtta ctatgatgcc tactataaaa
    21301 aggctggtca agtccgtacc ctcatcattc aagatttcga aaaagtcttc gcggattacg
    21361 atttgatttt gggtccaact gctccaagtg ttgcctatga cttggattct ctcaaccatg
    21421 acccagttgc catgtactta gccgacctat tgaccatacc tgtaaacttg gcaggactgc
    21481 ctggaatttc gattcctgct ggattctctc aaggtctacc tgtcggactc caattgattg
    21541 gtcccaagta ctctgaggaa accatttacc aagctgctgc tgcttttgaa gcaacaacag
    21601 actaccacaa acaacaaccc gtgatttttg gaggtgacaa ctaatgaact ttgaaacagt
    21661 catcggactt gaagtccacg tagagctcaa caccaattca aaaatcttct cacctacttc
    21721 tgcccacttt ggaaatgacc aaaatgccaa cactaacgtg attgactggt ctttcccagg
    21781 agttctacca gttctcaata aaggggttgt tgatgccggt atcaaggctg ctcttgccct
    21841 caacatggac atccacaaaa agatgcactt tgaccgcaag aactacttct atcctgataa
    21901 ccccaaagcc taccaaattt ctcaatttga tgaaccaatc ggatataatg gctggattga
    21961 agtcaaacta gaagacggta cgaccaagaa aatcggtatc gaacgtgccc acctagagga
    22021 agacgctggt aaaaacaccc atggtacaga tggctactct tatgttgacc tcaaccgcca
    22081 aggggttccc ttgattgaga ttgtatctga ggcagatatg cgttcgccag aggaggccta
    22141 tgcttatctg acagccctca aggaagttat ccagtacgct ggcatttctg acgttaagat
    22201 ggaagaaggt tctatgcgtg tggatgccaa catctccctt cgcccttatg gtcaagaaaa
    22261 attcggtacc aagactgaat tgaagaacct caactccttc tcaaacgttc gtaaaggtct
    22321 tgaatacgaa gtccaacgcc aggctgaaat tcttcgctca ggtggtcaaa tccgccaaga
    22381 aacacgccgt tacgatgaag cgaataaagc aaccattctc atgcgtgtca aggaaggggc
    22441 tgcagactac cgctacttcc cagaaccaga cctacccctc tttgaaattt ctgacgagtg
    22501 gattgaggaa atgcggactg agttgccaga gtttccaaaa gaacgtcgtg cgcgttatgt
    22561 atctgacctt ggtttatcag actacgatgc tagtcagttg actgctaata aagtcacttc
    22621 tgacttcttt gaaaaagctg ttgccctagg tggtgatgcc aaacaagtct ctaactggct
    22681 ccaaggggaa gtcgctcagt tcttgaatgc tgaaggtaaa acactggaac aaatcgaatt
    22741 gacaccagaa aacttggttg aaatgattac catcatcgaa gacggtacta tttcatctaa
    22801 gattgccaag aaagtctttg tccatctagc taaaaatggc ggtggcgcgc gtgaatacgt
    22861 ggaaaaagca ggtatggttc aaatttcaga tccagctatc ttgatcccaa tcatccacca
    22921 agtctttgcc gataacgaag ctgctgttgc cgacttcaag tcaggcaaac gtaacgccga
    22981 caaagccttt acaggattcc ttatgaaggc aaccaaaggc caagccaacc cacaagttgc
    23041 ccttaaacta cttgcacagg aattggcgaa gttgaaagaa aactagacag aacaaaacca
    23101 gccctaaggt tggttttttc ttctctacca actcccaata actattttgg ctttatttcc
    23161 agagtatttt atggtaaaat gaagagtaat aatatttatt aaagaggtaa aaacatgatt
    23221 gaagcaagta aattaaaagc tggtatgacc tttgaaacag ctgacggcaa attgattcgc
    23281 gttttggaag ctagtcacca caaaccaggt aaaggaaaca cgatcatgcg tatgaaattg
    23341 cgtgatgtcc gtactggttc tacatttgac acaagctacc gtccagagga aaaatttgaa
    23401 caagctatta tcgagactgt cccagctcaa tacttgtaca aaatggatga cacagcatac
    23461 ttcatgaata cagaaactta cgaccagtac gaaatccctg tagtcaatgt tgaaaacgaa
    23521 ttgctttaca tccttgaaaa ctctgatgtg aaaatccaat tctacggaac tgaagtgatc
    23581 ggtgtcaccg ttcctactac tgttgagttg acagttgctg aaactcaacc atctatcaaa
    23641 ggtgctactg ttacaggttc tggtaaacca gcaacgatgg aaactggact tgtcgtaaac
    23701 gttccagact tcatcgaagc aggacaaaaa ctcgttatca acactgcaga aggaacttac
    23761 gtttctcgtg cctaatctct agaaagaggt cattctatgg gaattgaaga acaacttggc
    23821 gaaatcgtta tcgccccacg tgtacttgaa aaaatcattg ctatcgctac tgcaaaggta
    23881 gagggtgttc actctttttc aaacagatca gtgtctgata ccctttcaaa actttcactc
    23941 ggccgtggcg tttatcttaa aaacgtggac gaagaactca cagcagatat ctatctctac
    24001 cttgagtacg gagtaaaagt tcctaaggta gcggttgcta tccagaaagc tgtcaaagat
    24061 gccgtccgta atatggctga tgtagaactc gctgctatca atattcacgt tgcaggtatc
    24121 gtcccagata aaacaccaaa accagaattg aaagatctat ttgacgagga cttcctcaat
    24181 gactagtcca ctattagaat ctagacgcca actccgtaaa tgcgcttttc aagctctcat
    24241 gagccttgag ttcggtacgg atgtcgaaac tgcttgtcgt ttcgcctata ctcatgatcg
    24301 tgaagatacg gatgtacaac ttccagcctt tttgatagac ctcgtttctg gtgttcaagc
    24361 taaaaaggaa gaactagata agcaaatcac tcagcatcta aaagcaggtt ggaccattga
    24421 acgcttaacg ctcgtggaga gaaacctcct tcgcttggga gtctttgaaa tcacttcatt
    24481 tgacactcct cagctggttg ctgttaatga agctatcgag cttgcaaagg acttctccga
    24541 tcaaaaatct gcccgtttta tcaatggact gctcagccag tttgtaacag aagaacaata
    24601 aaaagaaaaa gtgtttgata gatatcaaac actttttctt tgcctcccac tatctaaaaa
    24661 aatgataata gatataattg taaacaaaaa tccagatagg ttttgcatga ttgagaaagt
    24721 taaaaaaaac tatggcagag aatcgttaat ctcagattgt cggtaaaacg ataaacaagg
    24781 gcaaaaaaga aaccaatcag actataatat aataaactaa ttggatctct gtgagatagt
    24841 atcaaatgac taagcccaaa gataaggcct gataagatga catctaaata atacttggac
    24901 tagggaaaga aggtattcat aaaataccct ctatcaagag tctcctcaaa aacaggaccg
    24961 atgattacag gcaggacaaa agataagata gtcgataaaa aggttggttg tccatttgaa
    25021 agaaccacgg taaaatactc atcatgaata ttcctatgat taatcaaatg agcatagcgt
    25081 gcccaaaaat taccgagaat ctgataaacc acataagttg caaataagga gaagacaaat
    25141 gaccagttcc agctcttttt cttttttaac ctccaaatta atagaaggaa acttcccact
    25201 aataccattg ttaaaataag agaatagaca tcagctccta accctaaaat gatcgtcaca
    25261 tacaattcaa ttgtttgtgg taaataggta gatagtaaaa taataagcaa aaatattcca
    25321 aattgtctta gtttctttgt gtttctcatc gtactttttt gaaagattac cctgttcgga
    25381 agccgtactt ccaagcatct atataagaat taagtgccct tgcctcatat agggagcaaa
    25441 ttctctataa tataaccatc tactatatcc atcttcccaa acagcaagac cacctgaagt
    25501 ttgctccaag tcctcagttg aaataactgt aaatgtttct gtacctgtca ttgcaagtac
    25561 cttcttaaaa tagattgttg taggctcaca tttatagtat atttcttttt tgtctatttt
    25621 atagcccatc tcctcaacta tcaatttttc aacctgaatt gcatttttcc ataaaaaatg
    25681 agacctttct agtctcattt agtcattctt agtattttct aaatcgttga tagcgttctt
    25741 ccagcaactc ttctagcgat ttttgtgaaa gtctagccag ctccgtttgg agttcttttt
    25801 tgacactctt aatcagttct ttactagaaa gtcctacttc agaaatcacc ttatccacca
    25861 cgtccatttc taacagttca tgcgaagtga ttttcatcag ttctgctgct tccatggcgc
    25921 gagtaccgtc cttccataaa atggaagcaa agccttctgg actgagaatg gcatagatag
    25981 aattttccag catccagaca cggtccgcga cagctagagc cagagccccg cctgaaccac
    26041 cttcaccgat aataatggcg ataataggaa ctttcaggtc actcatttcc atgagattgc
    26101 gagcgatagc ttccccttga ccacgttctt ccgctccgac accaggataa gcacctgctg
    26161 tattgataaa ggtcacaact ggacggccaa atttctcagc ctgtttcatc aaccgcagtg
    26221 cctttcggta gccttctgga tgtggttggc caaaatttcg tttgaggttg tcttgcaaac
    26281 tcttgccttt ttggatacca accactgtta cagcttggtc tccaagccaa ccaataccac
    26341 caacaactgc accatcatca cgaaaagaac ggtcaccatg taattggata aattcatcaa
    26401 aaatgcctgt cgcaaagtcc aaggttgtca agcgactctg ctcacgcgct tctctgacta
    26461 tttttgcaat attcatctag gactccctcc atgcaatctg actaggctag caatcgtatc
    26521 tggtaagtct cttcttttga caatagcatc cacaaagcca tgttctaata ggaattctgc
    26581 cttttggaaa tcctcaggca agctttcacg aaccgtattt tcaatcacac gacgtccagc
    26641 aaaaccaacc aagctctgtg gttcagccag aatgatatcg ccttccatag cgaaagaagc
    26701 tgtcacacca ccagtcgttg gatctgtcaa aatggtcagg taaaagagac cagcatttga
    26761 atggcgttta accgccgcag agatcttagc catctgcatg agactcatga ttccttcctg
    26821 catacgggct ccaccagagg ctgtgaatag gacaactggc aatttttcga cagtcgcata
    26881 ctcaaacaaa cgagtgattt tttcacctac aaccgtaccc atagaagcca tgataaagtt
    26941 agaatccata atcccaagag ccacagtctg acctttaata agagcagttc ctgtcacaac
    27001 ggcttcatgc agacctgttt tttcacgcat agatgccagt ttcttttggt aaccagggaa
    27061 atgcaaggga tccttgcttt caatccctgt aaacaattct ttgaaggttc ccatatcaat
    27121 cgtcaaagcc aagcgttctt gggcagaaat acgaaaggta tagctacagt gcggacagat
    27181 acgttcactt cccagatcct tctgatagat ggtatgctta cagcctggac actgggaaaa
    27241 taattcatct ggaacctctg gcttagcttg aggtttttcc ctaaccgaac gattgggatt
    27301 gattcgaata tacttatctt ttttactaaa tagagccatt gattcccctt ttcggtttaa
    27361 actcttaaag tcattttatt ctttttcttg atatttaggt aagaaggttt ccatcaagaa
    27421 ggaagtatca taatccccag caatgacatt gcgatctgaa atgaggtcaa gctggaaatc
    27481 tgcattggtc tgcactcctt caatttctaa ttcatagagg gcacgttgca ttttcatcaa
    27541 ggcgtcaaaa cgattttcgc cgtgtactat gattttggca atcatactat cataataagg
    27601 cggaatggta taacctggat aaactgctga atccacgcgc aagccaactc caccacttgg
    27661 cagatagaga ttagtaatct tacctggact tggagcaaag ttaaaggctg ggttttctgc
    27721 attgatacga cactcgatgg catgaccgcg taggacaata tcttcttgct taacagacaa
    27781 aggctgacct gccgcaatgc aaatctgttc cttaacgata tcaacacctg aaacaaactc
    27841 tgttactgga tgttctacct gaacacgagt attcatctcc atgaaataga aattgctact
    27901 tgcttcatca agaagaaatt caatggttcc tgcattctca tagccaacaa actctgccgc
    27961 tcgaacagca gcagcaccta tttcatgacg cagcgttttt ccgattgcaa tcgagggact
    28021 ttcttccaaa accttttggt tattcctttg aagagaacaa tcccgttcac ccaagtgaat
    28081 cacatgtcca tgctcatcac ctaggatttg aacctcaatg tgccgagctg gatagataac
    28141 ccgttctatg tacatggcac cattgccata attggccttg gcctcactag aggcagtttc
    28201 aaaggcagaa acgaggtcat ctggtttttc aaccttacga atccctttac cacctccacc
    28261 tgctgaagcc ttgagcataa caggatagcc aattttttca gcaacaatca aagcttcttc
    28321 agagttatgc acttctccat ctgaacctgg tataacaggc acacctgctt taatcatctg
    28381 agcacgcgca ttgatcttat cccccatcat atccataaca tgaccagatg gaccgataaa
    28441 cttgatacct acttcttcac acatggtcgc aaatttggaa ttttcactga gaaatccaaa
    28501 accagggtga atagcttctg cctcagtcaa gactgcagct gatagaactg cattaatatt
    28561 gagataagac tctgttgcct tgccaggacc aatacaaact gcttcatctg ccaacagcgt
    28621 atgaagagct tccttatcag cagttgaata aaccgctacc gtcgcaatcc ccaattcacg
    28681 tgccgcacgg ataatacgaa ccgcaatttc accacgattg gcaattaaaa tttttcgaaa
    28741 catggagaac ctccttagtt cccaattgca aaagtaaggg taccactggc tgcaagcttg
    28801 ccatccactt cagcctttgc ttcaaccaca gctatggtgc cacgacgttt tacaaaagtc
    28861 gctgtcataa ccaattggtc gcctggtaca acttgcttct tgaacttaac cttatccata
    28921 ccagcgtaaa agaccagttt tcctttattt tcaggttttg ataactccaa cacaccagca
    28981 gtttgcgcca aggcttccat aatcagaaca cctggcataa ctgggtattg aggaaagtgg
    29041 ccgttaaaga aaggctcgtt gatggtcaca tttttgatag caacaatggt atcctcgctc
    29101 acctccaaga cacggtccac tagaagcata ggataacggt ggggaagggc ttctttgatt
    29161 ccttgaatat cgatcatttg atacgtacca atcctttacc aaactcaacc atttcttcgt
    29221 tagagacgag aatttccgtt accacaccat ccttaggagc tgggatttca ttcatgactt
    29281 tcatggcttc gataattacc aatgtttgac cttttttgac actatcacca actgtaacga
    29341 aggcaggttt atctggtcca gcagccaagt aaaccactcc aacaagtgga ctctctacaa
    29401 gatttccctc agtagccaca cttgcttcag ctggagctgg aacttcttct gctacagtct
    29461 ctgctggagc agatgtagga gctactggac tcggtgttgc tagaacgggt gctggagcga
    29521 cttgagttgc aacttcaggc acaggtctcg cttcattctt gctaaactgc aactcatccg
    29581 tcccattttt ataagaaaat tctctcaaac ttgactggtc aaattgagtc atcaagtctt
    29641 taatatcgtt taaattcata cttatctatt ctcccaacgt ttgaaagcaa gaactgcatt
    29701 gtggcctcca aaaccaaaag tatttgaaat agcgtatgga atttctttct ccaagccttg
    29761 tccataaacg acattagctt cgatataatc tgatacttca cttgtcccag ctgtcattgg
    29821 tacaaagtta tgacgcatag cttcgatggt gacgatagct tctactgcac ccgcagcccc
    29881 cagcaaatgt cctgtaaaag acttggttga tgatacaggt acttccttac caagaacagc
    29941 tacgatagca ccactttctc ctttttcatt ggcaggagtt gacgttccgt gagcattgac
    30001 ataggctact tgctctggag aaatctcagc ttcttccaag gctagtttga tggccttgat
    30061 agctccctga ccttctggat gtggagaagt catgtggtag gcatcacaag tatttccgta
    30121 accaaccact tcagccagga tagtagctcc acgtttttca gcgtgttcaa gactttctag
    30181 aaccaacatc cctgaacctt cacccataac aaacccattg cgatccttat caaatgggat
    30241 cgaagcacga gttggatcct ctgtagtaga gagagctgtt aaggcttgga aaccagcgat
    30301 ggcaaaaggt gtgatagaag cttctgttcc tcccaccaac atcacatctt ggaaaccaaa
    30361 cttaatagag cggaaggcat ccccaatcgc atcatttgat gaagagcagg cagtattgat
    30421 agatttacaa acaccatttg caccaaaacg catggctaca ttcccagaag ccatatttgg
    30481 taaagctttt ggaagagtca ttggtttgac acgtttgggt cctttttcat gaaggcgaag
    30541 tacctgatct tcaatttcct tgattccacc aataccagat gcaacgataa caccaaaacg
    30601 atccctatta agagcctcta catcaagatt ggcatgattt acagcctctt gggctgcata
    30661 caaggcatat aaagaatagt tatcaaaacg gttggtatct ttttttacaa agtatttatc
    30721 gaacggaaaa tcttggattt ctgccgcatt atgcacatca aagtcactat gatcaaattt
    30781 tgtaatgcca ccaatgccga ttttcccagt tgctaaacta ttccaaaatt cttctggtgt
    30841 atttccgatt ggagatgtta ctccataacc tgttaccact actcgattta gtttcattct
    30901 tttcacctct agctttcgct acatacttaa gccaccatca atggcaacca cttgaccagt
    30961 tagataatct tggcctgcta aaaatactgt caaatctgca acctgctctg cctgcccaaa
    31021 ttctttcatc ggaatctgag ctagtgtagc ttccttaatc ttatctgata agatagctgt
    31081 catatcagac tcaatcattc ctggagcaat cacattgact cgtatattcc gactagcgac
    31141 ctcgcgtgcc acagacttgg taaagccaat caagccagcc ttagaagcag catagttagc
    31201 ttgaccaata ttccccatca aaccaacaac actagacata ttaatgatag caccttctct
    31261 ggctttcatc atcggtttca agactgattg tgtcatatta aaggcaccag tcagattgac
    31321 cttgagcact ttttcaaaat ctgcttctgt catcttaagc ataagagtat cttgggtgat
    31381 ccctgcattg ttgaccaaaa catctactga acccagttct gcaatagctt gatcaatcat
    31441 acgcttagcg tctgcaaaat ctgatacatc tcctgaaatg ggaaccacct tgataccata
    31501 gtttgaaaac tcagcgagca attcttctga gattgcccca cgactgttta agacaatgtt
    31561 ggctcctact tgagcaaact tgtgggcgat ggcaagacca attccacgac tcgaacctgt
    31621 aataaagata tttttatgtt ctagtttcat ttttttcctt tcaaaacttc tacttatttt
    31681 agtctatttc tctaaaagtg ctactaaact cgcttgatct tccacatgag ctaagtgagc
    31741 agtttgatca atttttttaa caaaacctga caagactttc cccggtccaa tctcgataaa
    31801 gttgcttatg cctgcttctt gcatgacccc aatactttca tagaaacgaa cgggttcctt
    31861 gacctgacgc gtcaagagct gagcaatgtc ctctttttgc atcacagcag cttctgtatt
    31921 gccgactagg ggacaagtaa aatctgaaaa acttacctga gctagagttt cagctagttt
    31981 ctggctagct ggctcaagga gagcggtgtg aaagggacct gacaccttaa gaggaatcaa
    32041 gcgtttggca cctgcttctt gcaaaagttc aaccgctcga tcaactgcaa ccacttctcc
    32101 agcaatgacg atttgtgcag gtgtgttata gttggctgga gtaaccactc caagttcaga
    32161 agctttttga caggcttctt caatgacctc tactggcgta ttgagaactg ctaccatctt
    32221 gccagagtca gcaggagccg cttcttccat ataggctcca cgcttagcta ccaaggcaac
    32281 cgcatcttca aaatccaagg cgccgcttgc caccaaggca gagtattctc caagagacaa
    32341 accagcaacc atatcaggct gatagccctt ttcttgcaat aaacggtaga tagcaaccga
    32401 agtcgctaga atggctggtt gcgtatagcg ggtctgattg agtttgtcct cttccgtatc
    32461 gatgagataa cgtaaatcat aaccgagcac ctgactcgct cgatcaatcg tttctttgac
    32521 aatcggatac tgatcataga aatcccgtcc catccctaga tactgggcac cttgaccagc
    32581 aaataaaaag gctgttttag tcatttctta caactcctgc ccagcgagag gcttcttctt
    32641 gaattttctt agcggctccg taatacaaat cttttaggat ttcttcagct gtttcttctt
    32701 tagaaacaag tcctgcgatt tgacctgcca tgacagagcc accctccaca tcaccgtgaa
    32761 caactgcttt ggctagggca cctgctccca tttgttcaaa gatttctaaa tcaggatctt
    32821 cctgcttaaa ggcatctttt tcagccagtt caaaatctct agtcaactga tttttaatag
    32881 cacgaacagc atgaccaaag tgctgagctg aaatcgtagt gtcaatatcc cttgctttta
    32941 aaattttctc cttgtagttt ggatgagcat tcgactcttt tgcaactaca aaccgtgtcc
    33001 ccacctgtac agcctctgca cctagcataa agccagccgc agcaccttca ccatccgcaa
    33061 ttcctcctgc agcaataaca ggaatagata cagctgtggc tacctgtcgc accaaggtca
    33121 tggttgttaa tttaccgata tgccccccag cttccattcc ttctgcaata acagcgtctg
    33181 caccgatttt ttccatgcgt ttagctaaag cgacactagg aacaacagga ataacgatta
    33241 tcccagcttc atggaaacgt tccatatact tgcttggatt tcctgctcct gttgtgacaa
    33301 ctttaacacc ttcttcaata acgagatcca cgatatcttc cacaaaggga gataagagca
    33361 tgatgttgac cccaaagggt ttatcagtca atgatttgat tttatcaata ttggccttga
    33421 caacttcttt cggggcattt cccccaccga taattcctaa tcctccagcc ttggaaacag
    33481 cccctgccaa atcaccatca gcaacccagg ccatccctcc ttggaaaata ggatagtcaa
    33541 tcttcaataa ttctgtaata cgcgttttca tagtgcctcc aaccttcctt gcttacgtaa
    33601 tagttcgatt tcaccataat ttgacagtca aactattacc taaacaagag ggagtgggtt
    33661 tctccctact ccttctacta atattctgct tatttttctt gctcttcaac gtaagcaacc
    33721 aagtcaccaa ctgttttcaa gtcattttct gcttcgattt ggatatcaaa agcatcttcg
    33781 atttctgaga ttacttggaa caagtccaat gaatctgcgt ccaaatcatc aaaagttgat
    33841 tcaagtgtta cttctgatgc gtcttttcca agttcttcaa cgataatttc ttgtactttt
    33901 tcaaatactg ccatgatagg actcctttaa aataaatagt ttttttataa caatgtgttc
    33961 accacatgat tacctaaatt gtaagaatga gcgtgcccca ggtcaagcct ccaccgaagc
    34021 ctgatagaag aacagtctgg ctaccatcta aagggatgag accttgttct acacactctg
    34081 aaagtaaaat cgggatactg gctgcactgg tattgccata ttccatcata ttggctggaa
    34141 gtttggctcg gtcaacacca atttttctag ccatcttatc caaaatacgg tcattggctt
    34201 gatgaagtag cagataatcc aagtctgtca cctctatagg agattcatca atagtctgct
    34261 tgatagactt ggctacatct cgaatggcaa aatcaaagac tgtgcgtcca tccatcttca
    34321 aaaacgaatc tgcactttct tgatctgaaa atggagaatg caaacctgaa tgcccataag
    34381 ttaaacactc gctgcgactt ccatcgctat tgagactctc agctaagaaa tgctcttgct
    34441 cgctagcttc taacaagaca ccaccagcac catctccaaa caacacagct gttgatcgat
    34501 ccgaccaatc gactgcctta gagagggttt cactaccaat caccaagcct ttttgaaagc
    34561 gaccagaagc gataaacttt tcagcagttg aaagagcaaa tacaaatcca ctgcaagccg
    34621 cggttaagtc aaaagcaaag gctttattag cgccaatatt agcttgaaca cgagcagctg
    34681 tagagggcat catcgaatct ggagtaatgg tagctaggat gataaaatcc agttcttttc
    34741 ctgttattcc agcttttgcc atcagtttct tagcaacctc tgtagccaaa tcactggtag
    34801 attctgttct tgaaatatgc ctttgtcgta ttcccgttcg acttgaaatc cactcatcat
    34861 tggtatccat aatctgagcc aagtcgtgat ttgtaaccac ttgctctggc acataatgag
    34921 caacctgact tatttttgca aaagccatta tttcaaatcc tccaaaaatt ggtaaagatt
    34981 agtcaagcct ttacccatga cagcaatttc ttcctcgctc atgccatcaa taattttttc
    35041 taccatggcc ttgtggaagc gtttatgcag tctatgaatc aagcgaccct tctttgtcaa
    35101 atgcagatgc accacacgac gatcctgttc tgaccgaact cgctcaatgt agcccttacg
    35161 ctctaaattg ttcaaacttg tcgtaacagt tccaagagtt accatcaact cttttgacac
    35221 ttgacttgga gtcacatctg gagccttacc gatgacatca atcgtatgca tttctttgat
    35281 ggagatatcc ttaaaacgac tacctctcaa gttcacttcc tcaattacaa ggacattgtt
    35341 aaatatagat gttaaatatt cattgattcg ttggtagtcc atttttcata tccctccttc
    35401 ttcaaaaaac ttttacaatc aaaacatttg acagaaagaa ttatatcaaa attcaaagaa
    35461 tgatgcaagt attttttatt ttcctgtaaa tttaggtctt cttctctccg aatgagctcg
    35521 cactccttct ttgaaatcct ctgtttgagc taaggatttc tgtaggttca gttctaaagt
    35581 agcgtaaccc tgccagtctt taaattggct ctcccaaacc aacttcttaa tggcagcata
    35641 ggaattactt gaagcacgtc ttaatttttt aagaagctgt tctctcgtct tttcaagttt
    35701 ttcagcttca gaaacgcggt aaaccaaccc ccattctagg gctttttctg ccgttaaagc
    35761 ctctcctgtc atagctaatt gagcagcacg cgtcacaccg atactgcggc tcaagagatg
    35821 aattccccct gcatctggag ccaaaccaac accaacaaag gcttggataa acttagcctt
    35881 atccgtcgcc aaacagaaat ctgccgcaac agccatattc gctgcggcac ctgcaacagc
    35941 accgtcaact tccattaaaa caggtttggc tatttgcttg attttataag aaatcgtatt
    36001 gaccaactct gcgatttttg tcaatgatgg aatatcatcc tcatccactg cccgcttcat
    36061 ctctaccaaa tctcccccaa ctgagaagac ctttccattg gcattgatta agataaaatg
    36121 cacagctgga ttttcttctg ccaaagtcag agcttctaaa atctcctcac acatgggaat
    36181 atgaaaacca tttgcgacct caggacggtt caaggtaagg attgccaagt cctcttcaag
    36241 ctgataaata atgtgttcca tcagggctcc tttttatttt ataagcagtt tatactcttc
    36301 gaaaatctct tcaaaccgcg tcagcttcca tctgcaacct caaaacagta ttttgagctg
    36361 acttcgtcag tcttatttac aacctcaaag cagtgctttg agcagtctgc ggctagcttc
    36421 ctagtttgct ctttgatttt cattgagtgt taaattattt cactgtcaaa gtatatcttt
    36481 tttaggagca gaaagcaaga aaaaatcgac tgaaagtgtc tcagccgata agaaaggctc
    36541 gctttaggct agaacgcatc ttattttctt cattgaaaaa agcctttctt tctgctataa
    36601 tcgtataaaa tacttacttt aggagttctt atgaaagttg ttaaatttgg aggtagttct
    36661 cttgcctctg ctagtcaatt agaaaaagtt ttaaacatcg tcaaaagcga ttcagagcgt
    36721 cgttttgtag tcgtttctgc gcctggtaaa cgcaatgctg aagatactaa ggttacggat
    36781 gccctgatta aatactaccg cgactatgtt gcgggtaacg atattagcaa gagccaaagc
    36841 tggattatcg accgctatgc tgctatggtt agtgaattgg gactaaaacc agctgtgcta
    36901 gaaaaaattt ctaaaagcat tcacgccttg gccactcttc ctattgaaga aaatgaattt
    36961 ctctacgata ctttcctagc agccggtgaa aataacaatg ccaaattgat tgctgcctac
    37021 tttaaccaaa atggtatcga tgcacgctat atgcacccta gagaagctgg gattgtggtc
    37081 acaagtgaac ctggtcacgc tcgcatcatt ccatcaagtt atgacaagat tgaagaattg
    37141 acaaacacca atgaagtcct tgtcattcct ggtttctttg gtgtcactaa ggaaaatcaa
    37201 atctgtactt tctcacgtgg aggttctgat attacaggtt ctatcattgc tgctggtgtc
    37261 aaagccgacc tctatgaaaa ctttacggac gttgatggta tctttgcagc ccaccctggt
    37321 attatccacc aaccacactc gattcctgag ttgacctacc gtgaaatgcg cgagttggcc
    37381 tatgcaggct tctcagtcct tcatgacgag gctcttcttc ctgcctaccg tggaaaaatt
    37441 cctctggtta tcaagaatac caacaaccct gaccatccag gtactcgtat cgttctaaaa
    37501 cacagtaatg atgaatttcc agttgtggga attgctggtg actcaggctt tgtcagtatt
    37561 aacatgtcga aatacctcat gaaccgtgag gttggatttg gccgcaaggt tctgcaaatc
    37621 ctggaagaac ttaacatcgg ttgggaacat atgccaacag gtatcgacga tctttctatc
    37681 attctccgtt ctcgccaact aactcccatc aaggaagaag aaatcctgcg tcagttggtt
    37741 caaaaggcta aagtagatca tgcagaaatc gaacacgacc tttctatcat tatgattgtt
    37801 ggtgaaaaaa tgaagagcca catcggagtg actgctactg cgacacgcgc tctatctgaa
    37861 aacaaaatca acatccagat gatgtctcaa ggttctagtg aagtttctat tatgtttgtt
    37921 gtcaataaag accaagagaa agcagcaatt aaagccctct acaatgcctt ttttggagaa
    37981 agtaaggaag actaagcatg gctcaatcac ttaacaaaac agtactcctc agtacgacag
    38041 gcacttccta cctctctatc gctgggaaag ttgggaaatt ccttgtcgga gatcaggctt
    38101 tggaatttta cccagatgtc aatgtcgaac aatttatcca gattccttgg agccatatca
    38161 atcagattgg agccaatgtc actggatgca aaatcagccg ccacttcgaa gtctttacag
    38221 acaaaggaaa attcctcttt gcttcaaaag actcaggtgc cattctcaaa attgcacgcg
    38281 aaaaactagg caatgacaag gtcgtcaaac ttccgaccct gattcagaca attagccaaa
    38341 aatttaaaaa tctatttgca aaaaagtaga aactttagta taatcatagc aacggataag
    38401 taggttatct tcttctttca gaaagtctgc gggtactgcg agcagatagg agggataggt
    38461 gaaattctac cgttagtaac aattacatac acaatcaagt gcacacctgt gaagttggat
    38521 ggaaccgtgg ccctgccact ccaacgtttt gtcaggcgtg cttttttcat aaaggagttc
    38581 ttatgttaga tatcaaacgt attcgtacag attttgaagc tgtcgcagaa aaattagcta
    38641 cacgtggtgt agatgctgct gtcttgaatg aaatgaaaga aatcgatgct aaacgtcgta
    38701 acatcttggt caaggttgaa actctcaaag cagaacgtaa cacagtttct gctgagattg
    38761 cccaagctaa gcgcaacaag gaaaatacag atgacaagat tgctgccatg caaaatctat
    38821 ctgctgaggt taaagccttg gatgctgaat tggcagaaat cgatgctaaa ttgacagaat
    38881 ttacaacgac tcttccaaat atcccagctg acagcgttcc tgttggggct gacgaagacg
    38941 acaatgtgga agttcgccgt tggggtactc cacgcgagtt tgacttcgaa cctaaagctc
    39001 actgggatct cggtgaagac cttggtatcc ttgactggga acgcggtggt aaggtaacag
    39061 gcgctcgctt cctcttttat aaaggcctcg gtgctcgttt ggaacgtgct atctacaact
    39121 ttatgttgga tgaacatgga aaagaaggct atactgaagt catcacacct tacatagtca
    39181 accatgattc tatgtttggt actggtcagt atccaaaatt taaggaagat acttttgaac
    39241 tcagcgatac caactttgtc ttgattccaa ctgctgaagt tcctctgaca aactactacc
    39301 gtgatgaaat cttagacggc aaagatcttc caatctactt cactgctatg agtccgtcat
    39361 tccgttctga ggctggttct gccggtcgtg atacgcgtgg cttgatccgt ttgcaccaat
    39421 tccacaaggt tgaaatggtc aaatttgcca aaccagaaga atcttacgaa gaattggaaa
    39481 aaatgacagc caacgctgaa aacattcttc aaaaactcaa ccttccatac cgtgtcgttg
    39541 ctctctctac tggagatatg ggcttctcag ctacgaagac ttacgacttg gaagtgtgga
    39601 ttccagcaca aaacaattac cgtgaaatct caagctgttc aaacacagaa gatttccaag
    39661 cccgtcgtgc ccaaatccgt taccgtgatg aagcagatgg caaggtgaaa ctccttcata
    39721 ccttgaacgg ttctggactt gcagttggac gtacagtggc tgcaattctt gaaaattacc
    39781 aaaatgaaga tggttctgtg accatcccag aagcacttcg tccatacatg ggtggagctg
    39841 aagtcatcaa accataaaaa ataaggttta gctatttcta gctagacctt ttttcgtaac
    39901 caaatcagat aagcacctag tacaaagaat aaaatagtta ggcatataat ggtttcagcc
    39961 aataccaggt aatccagaaa tggaagtttc aaaattccct gagccatctt gagcgaggtc
    40021 gctgtgataa tggttgggaa ggtgagggct gagaaggctg gttgaaaacc ttgttttaaa
    40081 atgttgggca gacgagttaa aacaaagaaa aagaaggatt gagaagccaa aatcatgaca
    40141 atcaagaccc aagtcggcag gctggttcct cctactcgaa ctagagaagc caagagtaga
    40201 gagaaaggag cacagtagat tccttcttgt ccaagcaagg ctagtgggag tggatgtttc
    40261 tttaaatcgc tataaataag gggatagaga tagaaggtca agagaaaacc aaaactcaag
    40321 gtcgcatagg caatttcgat aatacctacc agaggatagg tcaaggcagc cactgctatc
    40381 cccacataga gaaccgtcca gcttggagtg gcatgaaccc tccgctctgg acaagcaaac
    40441 ttgatggtaa aaccagcaat caaggtcaaa tccaagagaa atgaaaacca ccaaatccct
    40501 tgtgctacca aaggaagata agagaatacg cgaaagacat aggtcgataa aatcatccca
    40561 gccataggaa aggttgccat tcctgacaaa agagggggct tggtcaattc ttgcttggtt
    40621 tctttccaat taaagagatg cagaattaga aagtaaatcc ataaaaccaa accagtcaga
    40681 ctaaaaagat gggatagaac tggcaacata tctaaaataa gatttccagc tcctgccaaa
    40741 cctagcaaac aacctgaaaa tactaagggg agttttttca tcctaacctc caataatcat
    40801 gttagtttca gtataacata aaagcgctta aatgaggatt taaaaaaacg aagtccgatt
    40861 atttcagact tcattttact cagatatgaa ttaggcataa ggttgcaatt ctggattaat
    40921 tggtgtatta gctaagttgt tggcatagtt acagaggatt gctaggctga caccgaaaac
    40981 cacatccaag gcattttgtt gagtgtagcc agcttctaaa aactcagaca aggcttcatc
    41041 tcctacacga cccttggtat tgataactgc caaggtaaac ttagctaggg tatccaattt
    41101 aggatctgtt tcaattggag tacgattgcg aagagcttga atcaagtcat cattcatctg
    41161 gatttgtttg atggaaaagg ctgtgtgacc tgcgacacag aaggcacaac cattggtcac
    41221 ggctgccgtg atttgcacca cttcacgctc aacgggtgtc aggctgttgc gacggtggat
    41281 agatgagaca atttggtagg cttctaaaac agtcggggca ttggccaaga gaccgattag
    41341 gttgggaata tagccattgt tgtctttttc tactgtttca agaatttctt tcacttctgc
    41401 tggtgctgac tctactgtat ggatagtaaa tgttgtcata agatacctct tttcttatta
    41461 ttgacactaa tattattgga aaatcttata aaatcctgat tcctaagttt atctaagata
    41521 aagctttatt ctctcataag attttcgttg ttatattagt ttatcacact tccaatcact
    41581 tgcataatat atattatata tcaggctgat aaaaattatt tataggcaaa aaaatcacac
    41641 gagctgtgtg attccattat ttgtcaaaat actttttagt ttcagcaata acgactggcg
    41701 acaagaccaa gagggcaatc aagtttggca gagccatcaa ggcgttaacg atatctgcga
    41761 taatccagac catatccaac tcgataaatc ctcctaacaa gaccatgagc acaaaaacca
    41821 cacggtagag ccagataaag cgaaccccaa agaggaactc aaaacagcgt tctccgtaat
    41881 agttccaacc tagaatcgtt gtaaaggcaa aaagtacaag gaagatggtc aagagggcag
    41941 gcccaaagtg tgaaaagact gttgagaaag ctgactgagt caaggcaacc ccattcaagt
    42001 caccactcca aactccagtt accaagatgg tcaaaccagt tagagtacaa atgatgaggg
    42061 tatcaataaa ggttcctgtc atggaaatca aaccttgctc tactggttca tttgtcttgg
    42121 cagctgcagc tgcaatagga gcagaaccca gaccagattc gtttgagaac acaccacgcg
    42181 ccacaccatt ttgaatagcc atccgaacgc tagcaccagc aaatccacct accgcagcaa
    42241 ggggactaaa agctgaggta aagactaaag cgattgtgcc agggattttt ccgatattaa
    42301 agaaaataac tataagagtt cctaagatat aaatgatggt cataaaagga acaacagtag
    42361 ttgaaacctt agaaatagac ttgagtccac caaagactgc aatcgctaca aagacagaca
    42421 agacgagagc tgtgatgact ggcgaaatcg tcgttgtatt ttggatagat tctgtaatcg
    42481 agttgacttg ggtgaaggtt ccgattccca agagagcaac caatactcct gctactgcaa
    42541 acaaaacagc aagtggtcgc cacttttctc ccatccctag aaggatatag tgcatgggac
    42601 ctcccgctac tgcaccatgg tcgtccttgg tgcggtattt gatgaccaag agtccttccg
    42661 catacttggt agccattcca aagaaagccg ccatccacat ccaaaataga gctcctggtc
    42721 caccaacctt gatagccgtc gcaactccta tgatatttcc tgttccaaca gttgatgcca
    42781 aggctgtaca cagagctgca aaactggata catcaccatg tcccttatcc tggataaaaa
    42841 taagctgaaa ggccttgggc agacgcaaaa cctgcaagag tcctagccgc atggttaggt
    42901 aaatccctgt tccgaccaat aaaatcaaga ggggcggtcc ccaagcaaaa tcatcgattg
    42961 atttaagcaa ttctaacatt tccttctcct atcgtttcaa ccccaaaaga aagagcacat
    43021 gcaagataca tgtactctgg aatgcttaga taaatgctaa aaagcggtct atcctagctc
    43081 tgtcctttta cctgagagtt tgagcagttg cctgccttgc cccttcggtg cctttacggt
    43141 ctctccagag ttccgtccat ttacagtcat ggaaaatcaa acgattcccc acttctatta
    43201 aacttcattc ggtgttggta tttaattgat tctaatttta caaaaaatgt tggcttttgt
    43261 caatgtgttt attagtaaaa attagttcaa cagtttttac tttataaagt ccagaatact
    43321 gctatccttt aaaagtgaca atagtcgcac cactgcctcc agcattttgt ggggcatagc
    43381 cgaaactctt gacatgtttg tttctttgca agtatttggt aactccttca cggatgactc
    43441 ctgttccgat accatggatg atatcaactt gagccatatt gttaagcaag gcttggtcga
    43501 tgaaggtatc tagctcattc atggcttctt catagcgctt gcctcgaaga tccagtctag
    43561 cttgaggtcc tcgcccagaa gttcgtttca caacattgac ctgtttcttc ttgactggtt
    43621 tttcttgctg ggcttgaaca agatcaaact ctttctcttc caaggtcatc ttaatcaagc
    43681 caacttgggc ttcccagcgg ccgtccttga gttgactggt caaggtacca cgctgaccat
    43741 aactgagaac cacgatatca tctcccacct ttggagctcg ttttttcttg gccttttgaa
    43801 ggaccttgtt tttagacaag tccacttttt caggagccaa ttttttcaac ttggccttgg
    43861 cttcaatgat ttcgtggggc ttgagttggg atttactgtg gagatttttg agaatctggt
    43921 cactttcact tagggccata tccacaatct cagcagcctg ttcacgcgcc ttgttaagct
    43981 cggtttcctt ttcacgatta agctcgttgt agagtttttt tagcgcacgg ttcatcttga
    44041 gattttcttg ctccacctca cggatattgt ccaaacgttt gcggctttcc agcgtctgct
    44101 cttctaattg ctcaatgata cgattgacgt cattgtcctg atcgatctgc tgactggcat
    44161 ctcctacgat aacttcagat aggcctagac gtttggcaat ttcaaaggca ttacttcggc
    44221 caggaacacc ctgcataaag cgataggtcg ggcgaagagt tgcagtatca aactccatac
    44281 tggcattttg cacaaaggct gtctcaatac cgtaggcctt gagttctgga tagtgggtcg
    44341 tcgccatggt cttgatttga cgcaggcgaa ggtcctccag aatagccatg gcaagggctg
    44401 ctccctcttg gggatcagta ccagccccca actcatccaa aagtaagagt gaatgttggt
    44461 tgaccttgcc aagaatatcc acgatattgg tcatatggct agagaaggta gacaagctct
    44521 gctcaataga ctgctcatct ccaatatcag caaagatttc ttcaaaaata ccaacacgac
    44581 ttcccttgtc tgctaaaatc ggcaatcctg actgggccat gacctgtgtc aagcccagag
    44641 ttttgagcat gatggtcttc ccacctgtat tgggacctgt aatgacaata gctgttaaat
    44701 cttgaccaaa atagacatca tttgcgacgg catttttgac caaaggatgg cagacatgga
    44761 gcagttgaat ctcttgattt tctgacagct gaggcacgac tgcttgtctt tcttggataa
    44821 atcgaacctt ggcacgaatc aagtccagat gaccgataat ccaagcgtca ttagcaatct
    44881 cagccgcatg agggcggaca cgctcagaaa tttcttggag aatgcgaagc atttcatagc
    44941 gctcatctgc tcgcagacta gcaatttctt cgctcagttt gactacctca cgtggttcga
    45001 tatagacggt gtttccacta gcagaaatat catgaacgac acctgcaatc ttattgcggt
    45061 aggtgttttt gactggtaaa acctgacggc catttctgct agcaacaatt ccttccgtca
    45121 acatctgcgc tttttgcttg agtaagtctt gtaaaacatc gcgcacctga ctctcgctat
    45181 catgtatttt tcgacggatt cgcgccaatt cttcactggc aaaattttca atgaaacccg
    45241 catcattaaa ggcctgaaga tttccttgta attgcggaaa atcatgtaat ttctcaaacc
    45301 aaagggctaa ttcttccaag ctgacatttt ccagattggc gtaaaaattt tgaagttctc
    45361 ggctggcaag aagcacgcgt ttcaagagta ggaactcctc gatattgaga tccgctccca
    45421 tctccaacct cttgcagact cctgcaattt ccttagttga gagaatagta aaatgcggtt
    45481 gctcgacgaa aagagcctgc atttctttca tctcagcaaa agcctgtttg attttatctg
    45541 ctttggcagt cggagccagc tgtctcaatt gctccaagcc ctgctcggtc aacaaatgag
    45601 gctcaaacaa ggccttgacc ttatcgaact ctaatgtttc taatattttc ttattcatct
    45661 ttatttcctt gtctttgaat gtctaggtgt ggtagctttt tacattctga tagattcgag
    45721 tcaaatctgt aaacaaaggg ctaggaaaac tcctgccctt tttatccgat taaatttgtc
    45781 acccagattt gtttgagcca actggttgtt atcggtatgc tctggatgat gtgttttgcg
    45841 acgatactct tttcaagagg attttgtata actgccatgg ggatggtcgc caagattgtc
    45901 aaggccattt gcaagacaaa taaggtcacc aacatggaca agatacctgc tgaaacttgg
    45961 aacaacttac cacccagttt tttgctagga atcaagtgta agagaagacc aagcaaacga
    46021 ccaatgctat agacaatccc aaatacaagc aagtagccga tacctgcata aaagacctta
    46081 tccagctgaa agagttgatc cgatgggaaa aagaaagtcc cctgaccttc ctgcgaattt
    46141 gcataaggga gcaataaatg gaattgctct ccaagcccct tataaaactg gccagccata
    46201 aaagccgatg ccatggctga aatcaggtaa taaacctgta agagcaggcc tctccgatag
    46261 ccgatataaa atccccaaac caagaccaat agaagaagga gtgaaatcat aaggaatcct
    46321 caatcttgct ctgttcttgc ttacaagtca caagcttgtg acggagttct tctagctctt
    46381 gctccttatc gtcaaattca atctcacggc tgagctgagt tgataaacag ttgactgcca
    46441 acaaaagagc gattgtttca tcatctgtgc taggcatttg ttctttaatt gcttggtatt
    46501 tttctgtcgc aaccttagcg atttcctcca taaaaaggtt atcatgttcg cttgtcaagg
    46561 ttaacgattt tttcccgaat gtaaatttga atcgatttag atttgccata aaattcacct
    46621 cacgatatta taccaaaatt cgctaatttt gtcagttttt acaaatttta ctgcttttgt
    46681 ggtacaatag aaactatggc aagtatcaca ctcacaccaa gcgaaaagga tattcaggct
    46741 tttcttgaac actatcaaac cagtctggct cctagcaaga atccctatat ccgctacttt
    46801 ttgaaactac ctcaagcaac ggtttctatc tatacttctg gaaaaatctt gcttcagggt
    46861 gaaggggctg aaaaatacgc cagtttcttt ggctatcaag ctgtagagca aaccagcgga
    46921 caaaatcttc ctttgattgg gacagatgag gtagggaatg gttcctactt tggtgggctt
    46981 gcagttgtgg cttcctttgt cacacctgac cagcatgcct tcttacgaaa actcggtgtg
    47041 ggagattcta agactctgac cgaccaaaag attcgtcaga ttgctcctat tctcaaggaa
    47101 aaaattcagc accaggcact ccttctctca cccagcaagt acaacgaggt catcggagac
    47161 cgctacaatg ctgtttcggt taaggttgcc ctccataatc aggctatcta tctcctcctt
    47221 caaaaaggtg ttcagcctga gaaaattgtg attgatgcct ttaccagtgc taaaaattat
    47281 gacaagtact tggcacaaga gaccaatcgt ttcagcaatc ctatcagctt agaagaaaag
    47341 gctgagggca aatacttggc tgtcgcagtt tcttctgtca ttgcgcgtga tctctttctg
    47401 gaaaatcttg aaaatttggg acgagaactg ggttatcagc tcccaagtgg agctggaacg
    47461 gcttctgaca aggtggctag ccagattttg caagcctatg gtatgcaggg actcagcttc
    47521 tgcgccaaat tgcactttaa aaacactgaa aaagcgaaaa aacgcttaga aaggtaagtt
    47581 atgaattcat ttaaaaattt cttaaaagag tggggattgt tcctcctaat tctgtcatta
    47641 ctagctttaa gtcgtatctt tttttggagc aatgttcgcg tagaaggaca ttccatggat
    47701 ccgaccctag cggatggcga aattctcttc gttgtaaaac accttcctat tgaccgtttt
    47761 gatatcgtgg ttgcccatga ggaagatggc aataaggaca tcgtcaagcg cgtgattgga
    47821 atgcctggcg acaccattcg ttacgaaaat gataaacttt acatcaatga caaagaaacg
    47881 gacgagcctt atctagcaga ctatatcaaa cgcttcaagg atgacaaact ccaaagcact
    47941 tactcaggca agggctttga aggaaataaa ggaactttct ttagaagtat cgctcaaaaa
    48001 gcccaagcct tcacagttga tgtcaactac aacaccaact ttagctttac tgttccagaa
    48061 ggagaatacc ttctcctcgg agatgaccgc ttggtttcga gcgacagccg ccacgtaggt
    48121 accttcaaag caaaagatat cacaggggaa gctaaattcc gcttctggcc aatcacccgt
    48181 atcggaacat tttaagagac ctaagaggcc gagaatcacc aatctcagcc tcttcttcta
    48241 tcgtgagaag tgattgttta ttgacaaata ctcaatgaaa atcaaagaac aaactaggaa
    48301 gctagccgta ggctgcttaa aacagtgttt tgaggttgtg gatagaactg acgaagtcag
    48361 ctcaaaatac tgttttgagg ttgcagatgg aagctgacgt ggtttgaaga tattttcgaa
    48421 gagtataaaa taaaaacaat cccaactctc acctattcat gcaaaggaat tttatggaag
    48481 tttatttttc aggaaccatt gaacggatta tttttgaaaa tcccagcaat ttttatcgca
    48541 tcctcctcct agaaatcgac gatacggacg cagaggattt tgatgacttt gaaatcattg
    48601 tcacaggaac catggctgat gtaattgagg gcgaagacta tactttttgg gggcaaattg
    48661 tccagcactc caagtatgga gaacaactgc aaatcagtcg ttatgatcgc gcaaaaccaa
    48721 ctagtaaggg cttggtcaag tacttttcaa gtagccattt caaggggatt ggtctcaaga
    48781 cagctcagaa aatcgtggat acctatggcg aaaataccat tgacgaaatt ttgcaacacc
    48841 cagaaaagtt agaaggcatc gcaggactct ctgccaaaaa tcgcgaggct ttcgtctcca
    48901 ctctccgtct caactacgga acggagatgg ttttggccaa actagccaac tacggcattc
    48961 ccaacaaact agcctttcag attcaagact tttacaagga agaaaccctt gatgtggttg
    49021 aaaattatcc ctaccagctg gttgaggata tcaagggttt gggctttacc attgctgacc
    49081 aactagctga ggaactaggc atcgaaagtc aggctcctga acgcttccgc gccggtctag
    49141 ttcacagtct ttttcaggcc tgtatggaaa caggggacac ctatgttgaa gcacgggatt
    49201 tgctggaaca aacccttact ctccttgagt cttcccgtcc cgtagaacta gaccccagcc
    49261 aagttgccca agagctctcc tacctgatcg aagaagacaa ggttcagcag attgatacca
    49321 agatctttga caacagcctc tttttcgctg aggaaggcat ccgcagtcac ttggttcgta
    49381 tccttgaaaa aggaaaacag aagagtcatg atttagaaac cattcaaaaa catatcacta
    49441 ctatcgagga agagctggga attgagtatg ataacattca aaaacaggct atctgtgatg
    49501 ctatccagaa taaggtcttt atcctgacag gtggacctgg tactggtaag acaactgtta
    49561 tcaatgggat catcgctgtt tacgccctgt tagagggact tgacctcagg aagaaaagca
    49621 atctgcccat tcttcttgct gctccaactg gacgagccgc tcgccgcatg aatgaattga
    49681 caggtttgcc tagcgcgacc atacaccgcc acttgggaat gacaggtgac gatgatacca
    49741 gtcatctgga agattaccta gatgctgact ttatcatcgt ggatgaattc tctatggtgg
    49801 atacttggct ggccaatcaa ctcttctcca atatctcttc taacagtaag atcctcatcg
    49861 taggtgacag tgatcagcta ccttctgtca gtcctggaca ggttctagcg gatctgcttc
    49921 atattccttt gattcctcag actcgcttgg aaaaaattta tcgacaaagc gaagaatcaa
    49981 ccatcgtcac cctagctagt cagattcgac agggcatctt gccagctgat ttcacccaaa
    50041 aaaaagctga ccgttcctac tttgaaattg ctagtggcca tattcctgcc accattgaaa
    50101 aaatcttagg tgccgccctc agaaatggta ttcctgcccg tgatatccaa gttctggctc
    50161 ctatgtaccg agggacggca gggattgatg ctatcaatca gctcatgcaa gacctgctca
    50221 atcccccaca aaaagatcaa ctcagttttg aagttcctca gtgccactat cgtaagggag
    50281 acaaggtcat tcatttggtt aacgatgctg aaatcaatgt ctttaatggg gatttaggag
    50341 ctatcacaga cctgattcct ggtaaataca ccgaatcgaa acaagacgag attgtcattg
    50401 attttgatgg taatgaagtc tcttaccccc gtaacgaatg gtacaagatt cgcttggcct
    50461 atgccatgag tattcataag tctcagggaa gtgagttccc agttgtcatc ctaccgatta
    50521 ctagtgctag ccgacgtatg ctggagcgaa atctcatcta cacagccatt acacgtgcca
    50581 aaagcaaact catcttacta ggcgaattac aagccttcga ctatgctacc caacacatcg
    50641 gaactgcccg aaaaacctat ctgattgaac gcttcagtga tctactggag aatgttgaag
    50701 aaaagcaaca agctgtctct gaaacagtca catcaagtgc ctctgaacaa tcctacatcc
    50761 taaccgaaga aaactgggac agcattccag ccatgattgg gattacagac acagacctca
    50821 aagagatttt tggaaaatag tgcatcagaa aaaccaccaa ttcaggtggg ttttctgttt
    50881 attaagatta ttttactgtt gctgtgcttg taatcaattc aacagctttt ttgatagtga
    50941 tatcatgttt caacatgtca gctgaaagca agttttgaac ttgtgcaact tccatgttgt
    51001 agtctgctgc caattgctca acttcttttt ggatttcttc ttctgaagca tcaaatcctt
    51061 cagctttggc aactgcttcg ataacaaggt tagtcttagt acgtgactca gcttctgctt
    51121 ggtattggtt gtgaaggtct tcttgagtag ttccagtgat ttggaagtac atgtcagggt
    51181 tgatcccttg acgttgcaag ttcccaagga attcatttac tgaacggtga acttcttcgt
    51241 ggatcatttc ttctggaagt tctacgattt cagcattttc tacagctgta tcaattgctg
    51301 caccttcaac tgcatctttg taagcttctt ctttagcagc agccaattct ttgcggtatt
    51361 tttctttcaa gtcagcaagt gtttcaactt cttcatcaat gtcttttgca agttcatcgt
    51421 caagagctgg aacttcttta gcttttactt cgtggatagt tgtcacgaat ttagcttctt
    51481 tacctgcaag gtcttctgct tggtagtctt ctgggaatgt tacgataaca tcaacggttt
    51541 cgccagctga gtgacctacc aattggtctt cgaaaccagg gatgaattga cctgaaccaa
    51601 gtccaagtga gaagttttca ccttttccac cgtcaaattc aacaccgtcg atagaaccaa
    51661 cgaagtcgat cacaacagtg tcgccgtttt cagcagcagc ttccttgata accaattcag
    51721 ccaggttgtt gcgttcgcgt tcgatacgct cttcaacatc agcgtcagtt acttcttttt
    51781 ctacatcaac tgatacttca aggtttttgt agtcacccaa ttttacttca ggttttgtaa
    51841 cgacttcagc agcgataacc cagtcttgac ctttttccat tgaagttacg tcaatttttg
    51901 gttgggcaac cacttcaaga ccagcttctt ttacagctgc ttcataagcg tttggcaaaa
    51961 gagcgttcat aacgtcttgg taaagtgatt cttcaccaaa ttttttatcg aagataggac
    52021 gtggaaggtg acctttacgg aaacctggaa cattaagaga tttcttcact gacttgaaga
    52081 cacggtccaa ttctggtttg atttggtctt gagagatagt gaaagtcaag acaccacggt
    52141 ttgtttcttt gttttcaaat gatacagaca ttctgtcatt tctccttaaa attttttaaa
    52201 tacagtctat tataacattt tctataaata aaatctagac taatgcagcc aattatagac
    52261 aacaagcctt tttcctaact aaaa
//
LOCUS       DAVEHY010000013        50748 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVEHY010000013 DAVEHY010000000
VERSION     DAVEHY010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.013"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..235
                     /locus_tag="VUZ44_000902"
     CDS             <1..235
                     /locus_tag="VUZ44_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU0319846.1"
                     /translation="NQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            265..3615
                     /locus_tag="VUZ44_000903"
     CDS             265..3615
                     /locus_tag="VUZ44_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU0319847.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(4121..4591)
                     /locus_tag="VUZ44_000904"
     CDS             complement(4121..4591)
                     /locus_tag="VUZ44_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU0319848.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4608..6881)
                     /locus_tag="VUZ44_000905"
     CDS             complement(4608..6881)
                     /locus_tag="VUZ44_000905"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU0319849.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7228..10329
                     /locus_tag="VUZ44_000906"
     CDS             7228..10329
                     /locus_tag="VUZ44_000906"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU0319850.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLDITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVELLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYLIDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10412..11419
                     /gene="pfkA"
                     /locus_tag="VUZ44_000907"
     CDS             10412..11419
                     /gene="pfkA"
                     /locus_tag="VUZ44_000907"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU0319851.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDASSVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11478..12983
                     /gene="pyk"
                     /locus_tag="VUZ44_000908"
     CDS             11478..12983
                     /gene="pyk"
                     /locus_tag="VUZ44_000908"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU0319852.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(13727..13952)
                     /locus_tag="VUZ44_000909"
                     /pseudo
     CDS             complement(13727..13952)
                     /locus_tag="VUZ44_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            14800..15672
                     /locus_tag="VUZ44_000910"
     CDS             14800..15672
                     /locus_tag="VUZ44_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU0319853.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFNSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(15818..16162)
                     /locus_tag="VUZ44_000911"
                     /pseudo
     CDS             complement(15818..16162)
                     /locus_tag="VUZ44_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            16305..16616
                     /locus_tag="VUZ44_000912"
     CDS             16305..16616
                     /locus_tag="VUZ44_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319854.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            16620..17336
                     /locus_tag="VUZ44_000913"
     CDS             16620..17336
                     /locus_tag="VUZ44_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU0319855.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYSASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(17466..18281)
                     /locus_tag="VUZ44_000914"
     CDS             complement(17466..18281)
                     /locus_tag="VUZ44_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU0319856.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLIIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(18278..19183)
                     /locus_tag="VUZ44_000915"
     CDS             complement(18278..19183)
                     /locus_tag="VUZ44_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU0319857.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGWAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            19595..21724
                     /locus_tag="VUZ44_000916"
     CDS             19595..21724
                     /locus_tag="VUZ44_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU0319858.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            21711..22160
                     /locus_tag="VUZ44_000917"
     CDS             21711..22160
                     /locus_tag="VUZ44_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU0319859.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            22218..22490
                     /locus_tag="VUZ44_000918"
     CDS             22218..22490
                     /locus_tag="VUZ44_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU0319860.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(22844..23035)
                     /locus_tag="VUZ44_000919"
     CDS             complement(22844..23035)
                     /locus_tag="VUZ44_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319861.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            23463..24221
                     /locus_tag="VUZ44_000920"
     CDS             23463..24221
                     /locus_tag="VUZ44_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319862.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            24223..26211
                     /locus_tag="VUZ44_000921"
     CDS             24223..26211
                     /locus_tag="VUZ44_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0319863.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTIHKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(26253..26897)
                     /locus_tag="VUZ44_000922"
     CDS             complement(26253..26897)
                     /locus_tag="VUZ44_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU0319864.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(26923..27918)
                     /locus_tag="VUZ44_000923"
     CDS             complement(26923..27918)
                     /locus_tag="VUZ44_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU0319865.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            28625..30100
                     /locus_tag="VUZ44_000924"
     CDS             28625..30100
                     /locus_tag="VUZ44_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU0319866.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(30066..30781)
                     /locus_tag="VUZ44_000925"
                     /pseudo
     CDS             complement(30066..30781)
                     /locus_tag="VUZ44_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            30868..31005
                     /locus_tag="VUZ44_000926"
     CDS             30868..31005
                     /locus_tag="VUZ44_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319867.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            31036..31896
                     /gene="speE"
                     /locus_tag="VUZ44_000927"
     CDS             31036..31896
                     /gene="speE"
                     /locus_tag="VUZ44_000927"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU0319868.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            31893..33152
                     /locus_tag="VUZ44_000928"
     CDS             31893..33152
                     /locus_tag="VUZ44_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU0319869.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            33152..34279
                     /gene="nspC"
                     /locus_tag="VUZ44_000929"
     CDS             33152..34279
                     /gene="nspC"
                     /locus_tag="VUZ44_000929"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU0319870.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            34276..35361
                     /gene="aguA"
                     /locus_tag="VUZ44_000930"
     CDS             34276..35361
                     /gene="aguA"
                     /locus_tag="VUZ44_000930"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU0319871.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRSF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            35371..36246
                     /gene="aguB"
                     /locus_tag="VUZ44_000931"
     CDS             35371..36246
                     /gene="aguB"
                     /locus_tag="VUZ44_000931"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU0319872.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(36427..37236)
                     /locus_tag="VUZ44_000932"
     CDS             complement(36427..37236)
                     /locus_tag="VUZ44_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU0319873.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATAISRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            37508..37729
                     /locus_tag="VUZ44_000933"
     CDS             37508..37729
                     /locus_tag="VUZ44_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319874.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            37783..38454
                     /locus_tag="VUZ44_000934"
     CDS             37783..38454
                     /locus_tag="VUZ44_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0319875.1"
                     /translation="MKKRAIQILLVLSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLLLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYITSYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(38506..38703)
                     /locus_tag="VUZ44_000935"
     CDS             complement(38506..38703)
                     /locus_tag="VUZ44_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319876.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFLRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            38696..39604
                     /locus_tag="VUZ44_000936"
     CDS             38696..39604
                     /locus_tag="VUZ44_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU0319877.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            39601..40062
                     /locus_tag="VUZ44_000937"
     CDS             39601..40062
                     /locus_tag="VUZ44_000937"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU0319878.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            40052..40939
                     /locus_tag="VUZ44_000938"
     CDS             40052..40939
                     /locus_tag="VUZ44_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU0319879.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            40942..42825
                     /gene="cbpE"
                     /locus_tag="VUZ44_000939"
                     /gene_synonym="pce"
     CDS             40942..42825
                     /gene="cbpE"
                     /locus_tag="VUZ44_000939"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU0319880.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNFERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIVGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            42905..44035
                     /locus_tag="VUZ44_000940"
     CDS             42905..44035
                     /locus_tag="VUZ44_000940"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU0319881.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            44045..45307
                     /locus_tag="VUZ44_000941"
     CDS             44045..45307
                     /locus_tag="VUZ44_000941"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU0319882.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            45311..46108
                     /gene="proC"
                     /locus_tag="VUZ44_000942"
     CDS             45311..46108
                     /gene="proC"
                     /locus_tag="VUZ44_000942"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU0319883.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLILEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            46328..46966
                     /locus_tag="VUZ44_000943"
     CDS             46328..46966
                     /locus_tag="VUZ44_000943"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU0319884.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            46963..47853
                     /locus_tag="VUZ44_000944"
     CDS             46963..47853
                     /locus_tag="VUZ44_000944"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU0319885.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            47893..48210
                     /gene="yabA"
                     /locus_tag="VUZ44_000945"
     CDS             47893..48210
                     /gene="yabA"
                     /locus_tag="VUZ44_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU0319886.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            48213..49082
                     /gene="rsmI"
                     /locus_tag="VUZ44_000946"
     CDS             48213..49082
                     /gene="rsmI"
                     /locus_tag="VUZ44_000946"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU0319887.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            49309..49827
                     /locus_tag="VUZ44_000947"
     CDS             49309..49827
                     /locus_tag="VUZ44_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU0319888.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            49936..50583
                     /locus_tag="VUZ44_000948"
     CDS             49936..50583
                     /locus_tag="VUZ44_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU0319889.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKIES"
     gene            complement(50536..50730)
                     /locus_tag="VUZ44_000949"
                     /pseudo
     CDS             complement(50536..50730)
                     /locus_tag="VUZ44_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        15422 a         9074 c        11123 g        15129 t
ORIGIN      
        1 aaatcagaaa tttattatcc atgttttaag gaataataat tatagtcgag tgatatcagg
       61 aagtgctcag cctcagttac caattacaaa attaaaaaaa atacttctcc ccctcccccc
      121 actagccctc caaaatgagt tcgcagactt tgtagtccag gtcgacaaat cacaatttgc
      181 ttgtgagata gctataaaag tgtggagaaa tagcttgaaa tttagtataa tatagctaaa
      241 ctatttgttt aaagtgagaa aaaaatggga aattttagct ttcttttaaa aaatgacgaa
      301 tatgaatctt tttcaaaacc ttgcattgaa gctgaaaata tgattgctac atcaactgtg
      361 gctactgcct ttatggcgcg tcgtgctttg gagcaggctg tccattggat atatagtcac
      421 gattcatatt tagaagctcc ctatcgtgct actctatctt ctttagtatg ggatgatgat
      481 tttagggata tcgtagattc tgaactccac aagcagatag ttctgttgat tcggtgggga
      541 aaccatgctg ctcatggtgg tgaaattaag gaacgagaag cgattttagc tttacatcat
      601 ttgtatcagt ttgttaattt tatcgattat tgttacagca atgaatttgt ggagcgttat
      661 tttgatgaga agtgtttacc actttcagca aacatcaaat accgagaaac tccacaatct
      721 atgataaagt tacaagacag tttaccagaa ctgcctgatt ttcatgaaca gatggctgct
      781 cagtccgtag aagttcaaga gacttatact gaaaaacgtg agactgcagc gcaacggcaa
      841 gatgtgcctt tccatattga tcaattatct gaggcagaga caagaaagct ctttattgat
      901 atcgatctcc gtttagcagg atggatattt gaagaaaact gtcgtgttga gatagccgtt
      961 gatggtctca agcacggttc aggaattggt tactgtgact atgtacttta tggtaaaaat
     1021 gggaaaattt tagcgattgt ggaggctaaa aaagcctctg tcaatccaga agtaggggaa
     1081 gtacaggtca aagaatatgc tgaagctttg gagaaacata tcggctatca gccaatttgc
     1141 tttattacaa atgggttgaa gcactatata cttgatggtc cgaaccgccg ccagattgca
     1201 ggcttttact ctcaagaaga attgcaatta gtgatggata gacgtcatct tcaaaaaccg
     1261 cttgaggata tttctagtaa aattagggac gatatttccg ggcgtcacta ccaaaaacat
     1321 gccattgcaa gcgtttgtga agctttctct aatcatcgta gacaggcact tttggttatg
     1381 gcaactgggg cggggaaaac tcgtacagca gtttctctag ttgatatctt atcacgtcat
     1441 aactgggtaa aaaacgttct cttcttagcc gatagaactt ccttggttaa gcaagcctat
     1501 gattcgttta gaaaattact cccagatctt tccgtttgta acttcttaga agataaagaa
     1561 ggagctcaat caagtcgtat ggtcttttca acttatccga ccatgattgg agcgattagt
     1621 ggtcaagaag aagtaaatca acgccctttt actgttgggc attttgacct tatcataatt
     1681 gacgaatctc accgttctat ttatcagaaa tacaagtcca tttttgatta ttttgatgca
     1741 agaattgtag gcttaacagc tactccgcgt caagatttag ataaaaacac ctatggattc
     1801 tttaatttgg agaatggggt tccaacatat gcatatgatt tggaagaggc tgttaaagac
     1861 ggatatttag tagcctatca ttctatcgaa accaaactga aactacctac ggatggtcta
     1921 cattatgatg atttgtccga agaagaaaag gaacattttg atagcaaatt tgaagacaat
     1981 agctgtgaaa aagatattga tgggagtgta tttaattcct ttattttcaa taaaagtaca
     2041 gtagaaattg ttttaaatga actcatgaca agaggaattc agacagcctc gggtgatgaa
     2101 attggtaaaa ctattatttt tgctaaaaat catgatcatg cggaatatat cagaggtatt
     2161 tttaacaacc gctatcctga aaaagggagc gactatgctc aggtgattga ttatagtatt
     2221 aagcattatc agaccttgat tgatgatttt aaaattaagg agaagtatcc tcaaattgcg
     2281 atttctgtcg atatgttaga tacaggtatt gatgtaccag aggttgttaa tttagtcttc
     2341 ttcaagaaag tacgctctaa aactaagttt tggcagatga ttggtcgagg aacccgtcta
     2401 tgtaaagatt tatttggacc tgagcaggat aaggaaaact tcttggtatt tgattatggg
     2461 gacaattttg attattttcg tgcagatcca agagatggag agggtcgtca cattgtttcg
     2521 ctgactcagc gtttatttaa tatcaaagtg gacttgattc gagaacttca gggactccaa
     2581 taccaagaag atcagtttgc gagagcatac cgtcagcagc ttgtctcgga acttcaaggt
     2641 cgtatagaga gcttaaatga gttggacttc agggttcgta tggttttaga tacagtttat
     2701 agctatagga aattggaaag ttggcagaat ctaactgctg ttacaagtga aaccattcaa
     2761 aaaaatctct ctccgctttt atttgatgaa gataaagaag atgagatggc caggagattt
     2821 gatttgtggt tgcttcatat tcagttgggg caactgacag ctaaatcttc cactgttcat
     2881 atttcccaag tgatgaagac ggctagagct ctttctgcta ttggcaatat cccgcaggtt
     2941 tttgagcagg ctgaaattat caggaaagta caggagcctg aattttggaa agaagttaac
     3001 ttgtctgatt tggaaaaaat tcgtcttgct attcgagatt tattacagtt tttggataaa
     3061 acagaccgta aaccctacta tgttaacttt gaagatcgta tactctccac tgttcacgag
     3121 accacagcat ttttgcaggt caacgatctt cggtcttaca atgaaaaagt tgagcattat
     3181 ttgaaaactc atctggatga ggagtccatt tctaagctat accataataa aaagttgaca
     3241 tctgatgata tgcttgcact tgaaaaattg ctttgggaaa aattaggtag taaagcagac
     3301 taccaaagtc attatgaaaa taaggcaatt ccgagattgg ttcgtgagat tattggctta
     3361 gatagagagt ctgccaatcg tattttttct aaatttttgt cggatgagaa tcttaatgcc
     3421 aggcagattt catttgtaaa attgattgta gactacattg tagaaaatgg ttttttagag
     3481 acgaaagtgt taacgcaaga gccgtttaaa tcttatggtt ctgttcaact actcttccaa
     3541 caccaactac cagtacttcg taatattgtt caaatcattg aacttatcaa taatcgagct
     3601 ggagaagcgg cttaaattct aaagtgattg ccatgctgag actcatttaa aattaaaaag
     3661 agtagaaatt tatgctatat atgagaagtt ttattaggaa gaatgtcatc gttttcctag
     3721 aatacagtat cagttgttaa gtggttgata aatttcaaag tagatacttg taccacgatg
     3781 tttgttgatc gagttattaa caaaagagct actttgattt taaagaaata gaaaacaaaa
     3841 agccgagcaa gaattcaatt gcaggagaaa atgaaataat actcaatgaa aatcaaagag
     3901 caaactagga aactagctgc aggctgctca aaacactgtt ttgaggttgc agatggaagc
     3961 tgacgcggat tgaagagatt ttcgaagagt ataaatcttc ctaggataaa gcaaaacgca
     4021 tagtatcaag ggttttcaac acttgatact atgcgttttc tgatgttaaa gactttctac
     4081 caggtttttt aaaagcataa ttgttagttg tagtcattta ttattcttca aagaaaaatg
     4141 gtggggcgaa ttttttcagt tcttcaaagc acttttgagc agtatctgca tcttcacaga
     4201 tgataagaca gacatcatta ccacaaaggg tagcgatagc gtcagggaag ctcaaagtat
     4261 caatgataga accaaaggat tgagccagtc caggaagggt ttttagtagg acttggtgtt
     4321 gaactgggcg catccagaca agggcgtctt ccatgtagag ttcgagacgt ttttcccatt
     4381 ttgagatgga accattgtta agaacataat aagcgctatc ttcttcgcgg acttttgata
     4441 ggttcatatt tttgatgtcg cgtgagaggg ttgcctgggt tacttgaatg tcgttctcag
     4501 caagaagggc ttgcaactca gcctgtgtat gaatcttgtt ttttgtgata agagcgcgta
     4561 taagttggtg gcggtgttct gatttattca taataatgta actcctttta gcaaggtaag
     4621 gtaagcatgg actgagcgag gtcgacagtc aagtggtagt ctgtattgtc acggatggtg
     4681 atttcaaagt cagtagtata gaggactaaa cggagagtgt ctccttcttt tagcttgtaa
     4741 atagttggct gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat atcctctact
     4801 aacagtaaat catttctatt ttgtaaatta aggtaacctt ttgtcacgac tcgttgtgcc
     4861 tctggtctaa atggcaattc acagagattt tccaacatgt gatagcgacc gttgtcaatg
     4921 gttctagcac ttaaaatagc tggataaggt tgtaggtatt tcttttgccc aaattctagc
     4981 agttgggcag ataagagccc cttgtttgta ctggatttga tacgaagatt gagctgagcg
     5041 cgaccgttta ggtggagatc tttagtcaca ggaaggttaa tagtaatctg attggctttc
     5101 ccttgataga gctctgtatt gaaggtttgg tatgtcttac catagcgctc aaaatcctta
     5161 tctgggtact ggttttgaat agcttgctct tcttgaccaa gtgagaaggt ttcacagttt
     5221 tcttgcccac cgaagttatc aagtgataac caagtctgtg gagctgtatt gtcctgccag
     5281 ataacagtag gaagttgaaa gtctgtttcc tgtcctagta atttcttggt taataaggca
     5341 tttatggact cacggaagtc aattgattgc caattgttca tgtaaacatg ggcaccatta
     5401 tggaaaaaga gatgcttgtg tatatgagta ggaagagcat ggaacatctg gtaaacatga
     5461 agtggtttga cattccaatc ctgagaacca tgagtaaaga caacctctgc ctttacttta
     5521 tgggcattga gcagataatt gcggtcatgc caaaactgat tgtagtcccc agtttttcgg
     5581 tctagctgag ctttcacttt ttctaagtca gcttggtgag cttcattgcc acggatatag
     5641 tcgccagcta agagattacg agaataggtt aactcagcaa gggagtcaaa gtcctcacct
     5701 ggataaccac ctgggctagt caccagaccg ttttcacggt agtagttgta ccatgatgaa
     5761 attcctgcct cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc aagaccattg
     5821 gacatggtac ctagatagga aagtcctgtt gtagcaactt ttccgtttga ccaatcagcc
     5881 ttgacttgac gctggcgcgt gtgatcagta aaggcacggc aacgaccgtt aagccaatcg
     5941 atgacatttt tataagcctc gatttgctgg tagtctccat tagtcatgaa acctgtcgag
     6001 tctttggtac caacacctga gacatagaga ttggcaaagc ctctcggaag gaagtagtcg
     6061 tttagtgtat agctagagtt gatgtgagtt agcttttcct cagcctctgc tataagctca
     6121 gctttacctt ggggttggac gagatttagt tgaggtttct ctagctcaat cttgtgagga
     6181 agcttaacct caagctcgcc ctccatcttg tagagagcct tgtcactagc cttgtcattg
     6241 gttccctgat gataagggct ggctgtcatg atggcaggga tttttccatc aaaacgaggg
     6301 cgaataatgc taacctttac taggtctgat agcccttttt ggtcagtatc gacacgagac
     6361 tcaacgtaaa cgacttcacg aatgacatcc tggttagaaa aagtagccaa actcttgccg
     6421 ttaaagtagt ggtagtcatt atcctccgga ataagaccat cactaacaag ttggtcgata
     6481 agagtatttc cttttttggt gcgagtattg agtaactgat agagattttc aatcaagtca
     6541 ccatatataa tgggaaatcc agtttcttta cgaaaaacgt cactatcttc gaagtcaacc
     6601 aaataagaaa agcctaaaag ttgaaaagca acagtataaa aaatatctgc tgtcagttca
     6661 tcttctgatt gaaaaaatgt cagcaggtct gtttttttat cagctgctag gatagaaagt
     6721 gggtagttgg tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc aagtgagtct
     6781 ttgtgattgg ctgtattttg taaatcaaag ccacattttt ttagttcaga taagacattt
     6841 tcttttggaa aattgatata actatattga ttaaaacgca tagaacctcc atatagaatg
     6901 acagttaagg ttattatatc aaaaaaaaag cagaaaggga attgttaact tcaaaaggaa
     6961 ataatccaat aaaaatgaat aaagtactaa attcaatata gagaacagag taacaataag
     7021 aataaataga tagggtataa aagttctagg agatttatat tatatgcttt ctatttttat
     7081 atacaatata gtataaatat aaaaatgatg acaaaaatac aaatgaatag aaaataaatt
     7141 agtaagctga tgaaattttt ctcaagagaa gccatttata ggtgaaaatg gtataatata
     7201 gtgagaagga tagaggagaa gtgtaaattg atcgcacaac tagatacaaa aacagtctat
     7261 agttttatgg aaagcgtcat ttcgatcgaa aagtatgtga gagcagctaa agaatacggc
     7321 tacactcatt tggctatgat ggatattgac aatctttatg gcgctttcga ctttctagat
     7381 attacaaaaa aatacggcat tcatcctttg ctagggcttg aaatgacagt gtttgtagat
     7441 gatcaggaag tgaatttgcg ctttttagct ctatctagtg tgggctatca gcagttgatg
     7501 aagctttcga cagccaagat gcagggggag aaaacttggt cagtcctgtc ccagtacctg
     7561 gaggatatcg cggtcattgt gccttatttt gatagagttg agttgttaga actaggctgt
     7621 gattactata taggggttta tccagaaaca ctagcaagcg aatttcatca tcctatctta
     7681 cctctttatc gggtcaacgc ttttgaaagc agggatagag aagttcttca agttttaaca
     7741 gcgattaaag aaaatctacc gctcagagaa gttcccttgc gttcgagaca agatgtcttt
     7801 atatcagcaa gttctttaga gaaactattc caagagtgtt ttccgcaagc tttggacaat
     7861 ttagaaaagc ttatttcagg catttcttac gacttggata ctagtctgaa actgcctcgt
     7921 tttaatccag ctagaccagc agtagaggag ttgagagagc gtgctgaact ggggcttgtt
     7981 cagaaggggt tgactagtaa agaatatcaa gatagactag accaagaatt gtctgttatt
     8041 catgatatgg gctttgatga ttatttcttg gttgtttggg atttgttgcg ttttggacga
     8101 tcgaatggct attatatggg aatgggaagg ggttctgcag taggcagttt ggtttcttat
     8161 gccttagaca tcacggggat tgacccagta gagaaaaatc tgatttttga acgctttctt
     8221 aatcgtgaac gctataccat gcctgatatt gatattgata tcccagatat ttatcgtcca
     8281 gattttatca gatatgttgg taataaatat ggtagtaaac atgcggcaca aatcgttact
     8341 ttttcaacct ttggagccaa gcaagctctt cgagatgtct tgaaacgctt tggtgtgcca
     8401 gagtatgaat tatctgcaat tactaagaaa atcagttttc gtgacaatct taagtcggcc
     8461 tatgagggca atctccagtt tcgtcagcaa atcaatagta agttagaata ccaaaaagct
     8521 tttgagattg cttgcaagat agagggctat ccaaggcaaa cctctgtcca tgcggctggt
     8581 gttgtaatta gtgaccaaga tttaaccaac tacattcctc taaagtatgg tgatgaaatt
     8641 ccactgactc agtatgatgc tcatggagtt gaggctagcg gacttttgaa gatggacttt
     8701 ctgggactac gaaatttgac ctttgtccag aagatgcaag agttgcttgc tgaaacagaa
     8761 ggtattcatc tgaaaattga agaaatcgat ttagaagaca aagaaacgtt agctttattt
     8821 gcctctggta atacaaaagg tatctttcaa tttgagcaac caggtgccat tcgtctgctt
     8881 aagcgtgtgc aaccagtctg ttttgaagat gtcgtcgcga ctacttctct aaatcgaccg
     8941 ggtgctagtg actatatcaa taattttgtg gcaagaaagc atgggcagga agaagtgact
     9001 gttctggatc cagtactgga ggatattttg gctccaacct acggcataat gctctatcag
     9061 gagcaggtta tgcaggttgc ccagcgattt gccggattta gtcttgggaa agccgatatt
     9121 ttgcgtcggg ctatggggaa aaaggatgcc tctgccatgc atgagatgag ggcttccttt
     9181 attcaaggtt cattagaagc tggtcatact gtggaaaaag cagagcaggt ctttgatgtt
     9241 atggagaagt ttgcaggcta tggttttaac aggtcacacg cctatgccta ctcagcattg
     9301 gccttccagt tggcttattt taaaacacat tatccagcca tattttatca gattatgttg
     9361 aattctgcca acagtgatta cttaatagat gcacttgaag caggttttga agtggcgcct
     9421 ctgtccatca acacgattcc ctatcacgat aaaattgcca acaaggccat ctatctaggt
     9481 ttgaaatcca ttaaaggagt cagtaatgat ttagctctct ggattattga aaatagacct
     9541 tattctaaca ttgaagattt tatagctaaa ttacctgaga attatctgaa acttcctctg
     9601 ctagaacctt tggtaaaagt tggtcttttc gattcatttg aaaaaaatcg tcaaaaagta
     9661 tttaataact tagctaatct atttgaattt gtgaaagagt tgggaagttt gtttggagat
     9721 gctatttata gttggcagga atcggaagat tggacggaac aagaaaaatt ttatatggaa
     9781 caagagcttt tagggatagg tgtcagcaaa catccactac aagctattgc aagtaaggct
     9841 atttacccga ttaccccaat cggaaatttg tcagaaaata gctatgctat tattttggtt
     9901 gaagttcaga aaataaaagt gattcgtacc aaaaagggtg aaaatatggc cttcttacag
     9961 gcagatgata gtaagaaaaa attggatgtc actctctttt cagacttata tcgtcaggtt
    10021 ggacaggaaa taaaagaggg agccttctac tatgtaaaag gaaaaataca atcacgtgat
    10081 ggccgtctgc aaatgattgc acaagaaata agagaagcag ttgctgaacg cttttggata
    10141 caggtgaaaa atcatgaatc ggatcaagaa atttcacgta ttttagaaca atttaaaggc
    10201 ccaatcccag tcatcatccg gtatgaagag gaacagaaaa ccatcgtttc tccccatcat
    10261 tttgtagcta aatccaatga attagaggag aaattgaatg aaatcgttat gaaaacgatt
    10321 tatcgctaaa aatacggaaa atagaagaat tttaaaatca aatgtgatat aatcaagaag
    10381 aatgttaaaa gaaaaaggag cataaaccaa tatgaaacgt attgctgttt tgactagtgg
    10441 cggagacgca cctggtatga acgctgctat ccgtgcagtt gttcgtcaag caatttcaga
    10501 aggaatggaa gtgtttggta tctatgacgg atatgctggt atggttgccg gtgaaattca
    10561 tcccctagat gcatcttcag taggagacat catttctcgt ggtggtactt ttcttcactc
    10621 agctcgttat ccagagttcg ctcaacttga agggcaactt aaagggattg agcaattgaa
    10681 aaaacacgga attgaaggtg tagttgttat cggtggtgac ggatcttacc acggcgctat
    10741 gcgtttgact gaacatggct tcccagctat tggtcttcca ggtacaatcg ataacgatat
    10801 cgttggtact gactttacaa ttggttttga cacagcggtt actactgcca tggacgctat
    10861 cgataagatt cgtgatacat catcaagtca ccgtcgtact tttgtaatcg aagttatggg
    10921 acgtaacgct ggtgatatcg ctctttgggc tggtattgca actggtgctg atgaaatcat
    10981 catccctgaa gcaggcttca agatggaaga tatcgtagca agcatcaaag ctggttatga
    11041 atgtggtaaa aaacacaata tcatcgtctt agctgaaggt gtgatgtcag cggctgaatt
    11101 tggtcaaaaa cttaaagaag ctggagatac aagcgacctt cgtgtaacag aacttggaca
    11161 tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt ttggcgtcac gtatgggtgc
    11221 acatgctgtt aaacttctta aagaaggtat cggtggtgtt gcggttggta ttcgtaacga
    11281 aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa ggggcattgt ttagccttac
    11341 tgcagaaggt aagattgtgg ttaacaaccc acacaaagcc gatattgagc tatctagctt
    11401 gaataagagc ttgtcataat ttacaattta gttaataaga ccaaaaaggt catatatata
    11461 aaggagtcac aaaaatcatg aacaaacgtg taaaaatcgt tgcaactttg ggtcctgcgg
    11521 tagaaatccg tggtggtaaa aaattcggtg aggacggata ctggggtgaa aaacttgatg
    11581 ttgaagcttc agctaaaaac attgctaaat tgattgaagc tggtgctaac acattccgat
    11641 tcaacttctc acacggcgac caccaagaac aaggtgagcg tatggcaact gttaaacttg
    11701 cggaaaaaat tgcaggtaaa aaagttggtt tccttcttga tacaaaagga cctgaaatcc
    11761 gtacagaatt gttcgaaggt gaagctaaag aatattcata caaaactggt gaaaaaattc
    11821 gtgttgcaac taaacaagga atcaaatcaa ctcgtgaagt gattgcgttg aacgttgctg
    11881 gtgctcttga tatctatgat gatgttgaag ttggtcgtca agttttggtt gacgatggta
    11941 aacttggtct tcgtgtggtt gctaaagatg atgcaactcg tgaatttgaa gttgaagttg
    12001 aaaacgatgg tatcatcgct aaacaaaaag gtgtgaacat ccctaacact aaaattcctt
    12061 tcccagctct tgctgaacgc gataacgacg atatccgttt cggtcttgaa caaggtatca
    12121 acttcatcgc aatttcattc gtacgtactg caaaagatgt gaacgaagtt cgtgcaatct
    12181 gtgaagaaac tggaaacgga catgttcaat tgttcgctaa aatcgaaaac caacaaggta
    12241 tcgataactt agacgaaatt atcgaagcag ctgatggtat tatgattgct cgtggtgata
    12301 tgggtatcga agtaccgttc gaaatggttc cagtttatca aaaaatgatt atcaagaaag
    12361 tcaatgctgc aggtaaagtt gttatcactg caacaaacat gcttgaaaca atgactgaaa
    12421 aaccacgtgc aactcgttca gaagtatcag acgtattcaa cgctgttatc gacggaactg
    12481 acgctacaat gctgtcaggc gagtctgcaa acggtaaata cccactcgag tcagtaacta
    12541 caatggctac aatcgacaag aacgctcaag ctcttcttaa tgaatacgga cgtcttgatt
    12601 cagattcatt tgagcgtaac tctaagacag aagtaatggc ttctgctgtt aaagatgcta
    12661 ctagctcaat ggatatcaaa ttggttgtaa ctcttactaa gacaggtcat actgcacgtt
    12721 tgatttctaa ataccgtcca aatgctgaca tcttagcatt gacatttgac gaattgacag
    12781 aacgtggctt gatgttgaac tggggtgtta tcccaatgtt gacagatgct ccatcttcaa
    12841 ctgacgatat gttcgaaatc gctgaacgta aagcggtaga agcaggtctc gttgagtcag
    12901 gcgatgatat cgttatcgtt gctggtgtgc cagtaggaga agctgttcgc acaaacacaa
    12961 tgcgtatccg cacagtacgt taagaaaaat ataaaaacct atcatatcca gctttctagc
    13021 ctgtatgatg ggctcttttt ttgtccaggg ggcaaaaagg ggggcaaaac tttcataatg
    13081 gattgatact cttcgaaaat caaattcaaa ccacgtcagc gtcgccttac cgtatatatg
    13141 ttactgactt cgtcagttct atctacaacc tcaaagcagt gctttgagca acctgcggct
    13201 agcttcctag tttgctcttt gattttcatt gagtatgaaa taagatatgc acaaattgat
    13261 tagaaagtca aatgaatttc tacaaatgtt ttagcaatcg taatgtactt gtctagattc
    13321 gatctgatat attttcgatt taatgatatg gtatttaaaa cctccaaagt agcttgctcc
    13381 attcttttac ttacgtgagt gtagatgtta tttactgttt tagcgtttta gcgtttttgt
    13441 gttccactct aaccattata gcattcttct cagctagtgt actaaggagt gtgtgcctga
    13501 aaatatggga actaaggggc tggtttatcg gtttctctag tttagtattt gccttttgca
    13561 aagtgatgtt aaatgccttt ctctaaattt acatatcact attgtttaac aaaatctaat
    13621 ctattttagg tcacttattc tttttttgaa atgtagaatg aactttttca aagtttttcg
    13681 aatcttttaa aatttgtttg ttttatatcg ccattctccc ccttttttaa ttctccctat
    13741 atagcctgac aactttcccg atggtacgaa tatggttgct ttcgtctagg tggatgtcgg
    13801 ggtatttggg attgagtttt tttaaggtag ccttggcgga gtttcttgac atagttagcg
    13861 ccgtctactt ggaagatgcc gatggtatta tagtcaatct gtggggtatt cttgataaat
    13921 aggtagtcgc tgtttcttat ctttggctcc atggacttgc tgacgacata agcgattggg
    13981 tcgtagtcgt ctgggataat ggaaactcca tatctaaatc gttgtcctgc atcgagcggc
    14041 tacctgcaga gataaactac ctaacacgag agtaagtagt ctgtctgtag tcgtccagtc
    14101 tgatgatttt tacgatactt cgtttttctg atcatacagt tgcctctcgg cataggtcag
    14161 aactttacct tgtctgggtg gtgcccgttg gtcgtagata gattggatat cgctaggaga
    14221 atccttttga actggagaaa agagggcatc aatcaagcta ctgaatactt taactaagtc
    14281 aaatatagta tttttcttag tagacctaac ccttttttca taatttctaa tggtgttttt
    14341 acttatacct atcttagtac ccaattctta ttgagtccaa ccattactag tctatattgt
    14401 tttatagttg attgagtttg gaatagtacg ctgtagctgc taaaacattt ctaggaatta
    14461 atttgccttt cctaatagag ttgttcatat cttatttcaa tctactatat ttttcgcctc
    14521 taacaatcgc aatctcttct ttatctacga atgaaatcgc tttctatttt tgtaagtaaa
    14581 gcatcacacg aaatccacga aaatgaaaac ctttgttgtg ttttcgtaaa aaatttgttg
    14641 acagagcacg aaacgcctac tataattaaa tcaagcttaa ggaaataaca aaaaaacaaa
    14701 tcggagggaa agacgatgaa cacattaaat gagaaagtaa tcaatatctg taaagcagta
    14761 gttaaagaaa ctttaatcca agacatttag gagaaagaaa tgaagaaatc aagaaaatta
    14821 gccacattag gaatctgttc agccttgttt ttaggcttgg ctgcttgtca acaacaacat
    14881 gctacttctg aggggacgaa tcaaaggcaa agcagttcag cgaaagttcc atggaaagct
    14941 tcatacacca acctaaacaa ccaggtaagt acagaagagg tcaaatctct cttatcagct
    15001 cacttggatc caaatagtgt tgatgcattt tttaatctcg ttaatgacta taataccatt
    15061 gtcggctcaa ctggcttatc aggagatttc acttccttta ctcacaccga atacgatgtt
    15121 gagaaaatca gtcatctctg gaatcaaaag aagggcgatt tcgttgggac caactgccgt
    15181 atcaatagtt attgtctttt gaaaaattca gtcaccattc caaagcttga aaagaatgac
    15241 caattgcttt tcctagataa tgatgcgatt gataaaggaa aggtctttaa ttcacaagat
    15301 aaggaagagt ttgatattct attttcgaga gttccaactg aggcaactac agatgtcaag
    15361 gttcacgctg aaaagatgga aacattcttc tcacaatttc aattcaatga aaaagctcga
    15421 atgctgtctg tagtcttgca cgacaatttg gatggcgagt atctgtttgt aggccacgtt
    15481 ggggtcttag tacctgctga tgacggtttc ttatttgtag agaaattgac tttcgaagag
    15541 ccctaccaag cgattaaatt tgctagtaag gaagattgct acaagtattt gggcaccaag
    15601 tatgcggatt atacaggcga gggactggct aagcctttta tcatggataa tgataagtgg
    15661 gttaaacttt aatagtgtta tgatatgaca gtaatcttag gatttttatt tctatttttg
    15721 atgacttggt gggttatttc aatcgttaat agccagaaac cactcaaaaa tgaaacattt
    15781 attggctatg tccaaagata cgatattgat gggaatggct atcaatcatt accgtgtcct
    15841 cagaactgag aggagttctt gaaatcgtaa aaccactttg aacaagagtt acttcaaccc
    15901 attggctctg atggattaag ttgctttcgt gaataccaaa atcagccaca atttgttcat
    15961 aagtgcggta ttctcgcaca tattgaagag tggccataag aaggtcttct aggcttaatt
    16021 taggttttcg tccacctttt gcgtgtttaa gttgataagc tgtttttaat acagctaata
    16081 tctcttcaaa agtcgtgcgc tgaacaccaa caagacattt aaatcgtgca tcagttagtt
    16141 gtttacttgc ttcataattc atagaactac tataccatat tttgtttcgc aggaagtcta
    16201 atgctaaaat cttatcagtg agaagatttc ttaaagttta ttctttgtag tttcatctgt
    16261 attagtacat aatttaactt agagaaaata ggaggactaa tcgaatggaa ttaaaagatt
    16321 ttacagaaaa agaacaggaa atgattaaga aaaggcttac aatgtctaat attagtgaca
    16381 aagaaactac tgagaagatt ctggcgctag taccacaaga cttgattaag cgaatcccgt
    16441 tttttgtcag aaaacatgct acaacacgta cgattaaacg catttcaatt gaacaccctg
    16501 aactctacgc tgtagctcaa acaagtggtg agattccgga aaaagaacgc gaagaattgc
    16561 gtcagattat cacgactatc tttgaacaaa agatgaataa gcatagtatt aagtagagaa
    16621 tgaaaaaata ttttattagc ggtttgggaa gcaatgccta tcatagcaag gatttttttc
    16681 aagaactaga ttcgcaggtc tattttctaa atccatatga aaagcatctt cgagatgaaa
    16741 cagaattgaa atcatggttt aaaaatgaga ttgtagagga agaatctatc tgtctgatag
    16801 gtcattctct tggaggagat ttagctcgtt attccgcatc ggaatttgaa gaagtaaaga
    16861 aactgattct tttggatggt ggctatctag atttagataa gattttacct ttggatacag
    16921 agttagagga aactaaaaat tatatcaaat ctcaaattgt ttcggactta gctcttctta
    16981 cttctaaaga aaaatctgaa gcaaagcatt ggtcagaaaa tatggagaaa gctgtaagac
    17041 agtcctatca ctggaatgtt gagtataata gatatgagtt ggctataaat tatgaaaata
    17101 tagaagcgat actccgccta cggagaaaaa tacaagcttt taagagagaa gtgggagata
    17161 ccttgtttat tagtcctcgc tatcctaatg aagctacatg gagagaggaa gccctaaaag
    17221 aattgccaga ctattttgat actatttttt tagaaaactt tggccatgag ctttatactc
    17281 aagcacctaa agaaatcgct agtctaatga atgagtggct cgcttatttt ctatgagcta
    17341 cttgtattgc tggaaatggt ataagatgaa aatctacaag tcactaattt tcatataacc
    17401 aaaaaacgaa caggctcttt ttctgttatt cagaagagaa cttgttcgtt tttatcttga
    17461 ttttcttaaa aagctctata tacataggga ttttctggtt tatcgacttt ggtaaagctg
    17521 tcgatttcca aggttggaag gttttgtttg agttctttat ggtagtgatt gaccagtttt
    17581 cctttggctg aaatccaagt gttgttttca tactgccggg tattgccctt ggtcagcaat
    17641 ccatagacac cagaatctgc gatacagtgg ataataccga atcggaacag aaattgacta
    17701 ttggcatgac tggggtcgtt atagacaaag cctgtaaact ggattgtctt gccctcaaac
    17761 tcatctggat agtcgtagat agcctccatg acttccatat agttttcatt agtgatctga
    17821 atactatctt gggataagta tttatccgcc gccgttcgca tttccttttc ataggctgat
    17881 tttgaaaaat aagaactggt atctggtttc aaatattggc ttgtcgtccc ttcgcttgtc
    17941 tgaatggcta gatccgttcc ttctgatagg gggaaatgat aacctttagc agaaacggtc
    18001 tgagaatcca agctaacagt tgggaaagtt aagccgatga taagtggaat agccagaaga
    18061 gaaatactcg tcatcttggc caatcggctg ttcagatgac tgtgggtttt gacttgcttc
    18121 atccagatat acaattgaac aattgccaag ataaaggaaa gcaccatgga gatataggcc
    18181 agataggaat agtgcatgtt gatgtactgg tttagtttgc ccgacagatg gaggtaaata
    18241 gtcagttcaa aatagccagc taaaactaaa aatcgaatca taggatgact ccaatcaaga
    18301 gagaataggc taaaacgacc agagtcacaa tcgtaatgaa gtgactaata aatcgtgctt
    18361 tcaagtaatt tttcatcatg agaatatttt tgatatccag cattgggcca atgacgagaa
    18421 aggccagaac tggtgcccaa ccgaaactcg agagtagaga agcacctata aaggcatccg
    18481 cctcactaca gagcgaaaga agaaaggcca aaagcatcaa gagcaggatg gcaaaaagag
    18541 gagtcgcact gatagaggtc agaatccgag tcggaacgta gacctgtatt atagaagcaa
    18601 agaggcagcc aaataccaaa taacgccccg tatcaaaaaa ttcatcaatg gcctgcacaa
    18661 agacttgaaa aacttttttt gcagaactca agtaagaaaa atcatgctca tgacaagcca
    18721 gacgattttc tttctgaatc ggttcttgcc agaaaaatcc tagaaaaatt cctagtatta
    18781 cagccacaag aatggaaccc agagctcgta atagggcgac atggaaggag ttgccaaagg
    18841 cagaataggt cgcaaaaaga acaatgggat tgataacagg tgctgtcaca agaaaaggaa
    18901 cggccgtgta acttggaacc tttttttcca gaaaacgatt gatgatgggg acgattccac
    18961 attcacaaga agggaaaagt ataccgacaa aggtcccaaa aaagattctc ccccaacgat
    19021 ttcgagggag aaaatgataa accttgtcag gtgtgatata aacttcaatc agccctgaga
    19081 caatgcttcc tatcagaacg aagggaaggg cttcaatgat aatggagaga aaaatggctc
    19141 cagtttgaag tacactagat gggagttgtt gaaaagcagt catctagttt ttcttttctg
    19201 ctttgacttt tttctctttg tcatcaggga aagtaacttg tttcaaatca gggagtttag
    19261 caaactcttc aaacatcttg tccaagtcgt ctcgttttgt aaatttgaca gccataggtg
    19321 tacctcgatt ctaaattcta cctctattat actattattt tgcggaaaag ggagtttttt
    19381 aatttgtttt cgatagttga tacacttcga aaatctcttc aaaccacgtc agcttcgcct
    19441 taccgtagta cggttactga cttcgtcagt tctatccaca acctcaaaac agtattttga
    19501 gcagcctacg gctagcttcc tagtttgctt tttgattttc attgagtatg aaaaggattg
    19561 gagaaagcct tccagcttgt ggtataatag atttatggat aaaaaatatg aaaaaatctc
    19621 tcaggatttg ggagtgacgt taaagcaaat tgataccgtt ctaagtttga cagctgaagg
    19681 ggcgactatt ccctttatcg cgcgttatcg caaggacatg actggtagtc tggatgaggt
    19741 ggcgattaag gctattattg atttggataa aagtctgaca aatctcaatg accgtaagga
    19801 agctgtctta gctaagattc aagaacaagg taagttgacc aaggaattgg aagaagctat
    19861 cttagttgcc gaaaaattag cagacgttga agaactctat cttccttata aggaaaagcg
    19921 tcgtaccaag gcaaccattg cccgtgaagc tggactcttt cctcttgctc gcttgatttt
    19981 gcagaatata gttgacttag agaaagaagc tgaaaagttc gtctgtgaag gatttgcgac
    20041 tggcaaggaa gccttgaccg gtgcagttga tattttggtc gaagccttat cggaagatgt
    20101 gaccttgcgt tctatgactt atcaggaagt gctgagacac tctaaactta cttctcaagc
    20161 caaggatgaa agtcttgatg aaaagcaggt ttttcagatt tattatgatt tttcagagac
    20221 agttggaact atgcaaggct atcgtacctt ggctctcaat cgtggggaga aacttggtgt
    20281 cttgaagatc ggttttgaac atgcgacgga ccgtattctt gccttctttg ctactcgttt
    20341 caaggtgaaa aatgcttata ttgatgaagt tgttcagcaa tccgttaaga aaaaggtctt
    20401 gcctgctatc gagcgtcgta ttcggacaga attaactgag aaagctgaag aaggagctat
    20461 ccaacttttt tctgacaatc tgcgcaatct cctcttggtt gctccactga aagggcgcgt
    20521 ggttcttgga tttgacccag cctttcgtac aggtgccaag ctagctgtcg tggatgcaac
    20581 aggaaaaatg ctgacaactc aggttattta tcctgttaaa ccagcatcag ctcgtcaaat
    20641 cgaagaagcc aagaaagatt tagcagattt aattggtcaa tacggtgtag agattattgc
    20701 cattggaaat ggaacggcca gtcgtgaaag tgaagctttt gtagcggaag ttctgaaaga
    20761 tttccctgaa gtcagctatg ttatcgttaa tgaaagtggt gcttctgtct attctgccag
    20821 cgaacttgct cgtcaggagt ttccagactt gaccgttgaa aaacgctctg ccatttctat
    20881 cgcccgtcgt ttgcaagatc ctcttgcgga attggtcaaa atcgatccta agtcaattgg
    20941 tgtcggtcaa taccaacacg atgtcagtca gaagaaacta tctgagagtc tggactttgt
    21001 tgtcgataca gtggttaacc aagttggtgt caatgtcaat acagctagcc cagctcttct
    21061 ttcacacgta gctggactca acaaaactat ctctgaaaat attgtcaaat accgcgagga
    21121 agaaggaaaa atcacttcac gcgcccaaat caagaaagtt cctcgtctgg gagccaaggc
    21181 ctttgagcag gctgctggtt tccttcgtat ccctgaaagt agcaatatcc ttgataatac
    21241 aggagttcac ccagagaatt acactgcagt taaggaactc ttcaaacgtt tagatattaa
    21301 agacctaaac gaagaagccc aaagcaaact caagtcgctt tcagtcaagg aaatggcgca
    21361 agagttagac cttggtccag aaactcttaa agatatcatt gcagatcttc tcaaaccagg
    21421 tcgagatttc cgtgattcct ttgacgcacc tgtgcttcgc caagatgtcc tagatatcaa
    21481 ggacttagtg gttggacaaa agctagaagg agtggtgcgt aacgttgttg atttcggtgc
    21541 ttttgttgat atcggaattc atgaggacgg tctcatccat atttcccata tgagtcgcaa
    21601 gtttatcaaa caccctagtc aagtggtggc agttggagat ttggtgagcg tttgggttaa
    21661 gaaaattgat actgaacgtg aaaaagttaa tctgtctctc ctagctccaa atgaaactga
    21721 ctgattacgt caagcaggtt tcactagaag acttcggcag accttttatc catcatgtcc
    21781 agtggaatag gcgtctacgt tcgacaggtg ggcgattttt ccccaaagat gggcatttgg
    21841 attttaatcc caaggtttat caggaactgg ggttggacgt ttttaggaaa attgtccgac
    21901 atgaactctg tcattatcac ctctattttc aagggaaagg ctatcaacac aaggatcggg
    21961 attttaagga actgttgaaa gcagtggatg gattacggtt tgtaccatcc ttgcccaata
    22021 gtaactccaa gccaatcaag ctctatcgtt gccaatcctg ccagcaaagg tatcagcgta
    22081 agcgtaggat tgatacccaa cgctatcgct gtggactttg tcgaggaaag ttgctattag
    22141 taaatcagcc tgaggactga tgaaagccga gcctatccgt gatatactag tctaacctag
    22201 cagaaagagg aaatatcatg aacagtaagt tttataaaat gagacgaaat cgcatgattt
    22261 caggagtttt agcaggtctg tcagacaagt ggaactttga tgttaccctt gtacgttttc
    22321 tgtttgccat ttttacagtc gcaaactttg gacttggggt gattatctat atcatcctag
    22381 cttctatcat gccaaccaag gaagaaatcg aagcagaaat gtacggaaca ggcccacgta
    22441 aacgcaaaga agctcaagcc attgacgata atgaaggctg gttttggtga ggttttacaa
    22501 aagatttgga atacgcaaaa agctttaaat caatagtcta aactgcttga tttaaagctt
    22561 ttttactttt atactcaata aaaatcaaag tgcaaactag gaagccagcc gcaggctgta
    22621 atttagtcgg caatgtgaag ttgatatagt ttgcactttg atttttgaat agtattaata
    22681 atatttcgcc agcttcatcc acaaactata gtggattgga actagaatag gacacctata
    22741 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttcttatt
    22801 tcattttact ataaaagcag taatttaaac gcagtttttt aatctatttt tgctgttgag
    22861 acaatacatt tttggaaaaa tggtggatgc tgataacaac tgataaccag caaataacat
    22921 aagcagtgcc ggtaaattct gtactgataa agtgtgtgtg ttcaactaag agctgaccga
    22981 tgaatggaga gagcagatag agaagtccga tgagtatatg ttctttgtgt ttcattaaag
    23041 cgcaccttct ttccttatag gttgaacgac ttgcaagtgt taaattgaat ggtatgttat
    23101 ctaggtaagc ttactaaaat gttagttccc gcttcctcct tttcaaagta agccttttca
    23161 cacttatatt ttacaacttt aaaaatagga aatcaaatca ttttctaagt aattttgctt
    23221 atatttcacc caatcttaca aaaatgtaag attaaagtct cttttgtaag gttaggttat
    23281 ggcaagcggt ctttttttga tgtaaactag actcataaag aacaaaggag taacatcatg
    23341 aaacaaatct tacataagaa aactagaaaa ccaagtcaca aagaaattga gcgcgttcag
    23401 ctgggatgca ctatgatgca agctacattt catttgatgg gatattaaga aaggagattt
    23461 tcatgacact tttagatgta aaacacgttc aaaaaattta taaaacacgt tttcagggca
    23521 accaagtaga agccctcaag gatattcact ttaccgtaga aaagggtgac tacgttgcca
    23581 tcatgggtga gtctggttct ggtaaatcaa ctcttctcaa tattctagct atgttggata
    23641 aaccaagtcg tggtcaggtt tacttgaatg gaactgacac cgcaactatt aaaaattcac
    23701 aggcttctag tttccggcgt gaaaagctag gatttgtctt ccaagacttt aacttgctag
    23761 atactctgtc tgttaaggac aatatcttgc ttccgcttgt cttgtcaaga agacctataa
    23821 cggagatgat gaagaaattg gtggtgacag ctgagaatct gggtattaac caattgcaag
    23881 agaagtaccc ttacgagatt tctggtggtc agaaacagcg tgtagcagta gcccgcgcca
    23941 tcatcacaga acctgaaatt ctccttgcgg acgagccaac aggagccctt gattccaagt
    24001 catctgcagc cttacttgat gtctttaatg aaatcaatga gcgtgggcaa accatcctca
    24061 tggtaaccca ctcaacagca gctgctagca gggccaagcg tgttctcttt atcaaagacg
    24121 gcattcttta caaccaaatc taccgtggag agaagacaga gcgtcagatg ttccaagaaa
    24181 tctctgatac cttgactgtc atggcaagcg aggtgaatta gtatgtttcg attaaccaat
    24241 aagttagcgg tatcgaactt gattaaaaac cgcaaactct actatccctt tgcactggct
    24301 gttctcttgg cagtcaccat cacctatctc ttttactccc taaccttcaa tccaaagatt
    24361 gcggaaatcc gtggaggaac caccattcaa gcaacacttg gatttggtat gtttgtcgtt
    24421 acccttgcgt cagccattat cgtcctctat gccaatagtt ttgtcatgaa aaaccgttcc
    24481 aaggaactgg gtatatatgg catgttaggc ttggagaagc gccatctaat cagtatgacc
    24541 tttaaggagt tagtgctatt tgggattcta actgttggag caggaatcgg tattggagcc
    24601 ttgtttgaca agttgatttt cgctttccta ctcaaactga tgaaattgaa ggtggaactg
    24661 gtcgctacct tccagatgaa agttgttatt acagtacttc ttgtctttgg attgattttc
    24721 ctaggcctca tgttcctgaa tgcccttcga atcgcccgta tgaatgccct ccagctctca
    24781 cgtgagaaag ctagcggaga gaaaaaaggt cgcttccttc ctctccaaac gattcttggt
    24841 tccataagtt tagggattgg ctattatctt gcccttacgg taaccgatcc tcttacagcc
    24901 ctaacaacct tcttcctagc tgttttgctg gttatctttg gtacttatct attgtttaat
    24961 gcagggatta cagtcttcct acaaatctta aagaaaaaca agaaatacta ttaccaacct
    25021 aataacctca tatctgtttc caacttgatt ttccgtatga agaaaaatgc ggttggacta
    25081 gcaaccatcg ctattttgtc aacaatggtt ttggtaacca tgtcagcagc gacaagcatt
    25141 ttcaattccg cagaatcctt taaaaaagtt ctaaatcctc atgattttgg ggtttcaggg
    25201 caaaatgttg aaaaagaaga tttggacaaa ctcttgagcc agtttgcaag tgacaaaggt
    25261 tatagtgtca aagagaaaga agtacttcgt tacagtaact ttggtattgc aaatcaagaa
    25321 ggaaccaagt taactatttt tgaaaaagga caaaaccgtg tccaaccaaa aacagttttc
    25381 atggtatttg accaaaaaga ttatgaaaat atgactggtc aaaaactgtc tctatcagga
    25441 aatgaggtcg gtctctttgc caaaaatgac ggactgaaag gacagaaagc tctaactcta
    25501 aatgatcatc aattttctgt caaagaagaa tttaataaag atttcattgt caaccatgtt
    25561 ccaaataagt ttaatatctt gactactgat tacaattacc ttgttgttcc tgatttacaa
    25621 gcctttttgg atcaattccc agattcggct atctataatc agttttacgg tggtatgaat
    25681 gtagatgcca gcgaagaaga acaactcaag gtcgctgagg agtatgaaaa ctacctcaat
    25741 caatttaatg ctcaattaga cacagaaggt agctatgttt atggtagcaa tctagcagat
    25801 gctagtgctc agatgagtgc cctctttggt ggtgtcttct ttatcggtat tttcctatcc
    25861 attatcttta tggtcggaac tgttctggtc atctactaca aacaaatttc tgaaggctac
    25921 gaagaccgtg aacgctttat tatcttgcag aaagtcggtt tggaccaaaa gcaaatcaag
    25981 caaaccatcc acaaacaggt tttaactgtt ttcttccttc ctttgctctt tgccttcata
    26041 catctcgcct ttgcctacca tatgcttagc ctgattttaa aagtgattgg tgtactggat
    26101 acgactatga tgttgattgt gaccttgtct atctgcgcta tcttcctcat cgcctatgtg
    26161 ctgattttca tgattacttc aagaagttat cgcaagattg tgcaaatgta aaaaagatac
    26221 ctcgacttca aaatcgaggt atttcttgta ttttaaatgc tgaaaagttg ttcgagcagg
    26281 aaggtaactc ccatggtcaa gagaccaata gcaaggttcc gaatcatagc tgttttggtt
    26341 ggggcttttc caagtctagc acttgtgtaa ccagtgagaa gaagggccac accgacaata
    26401 aggacggtag cagggatgcg gtaatcactt ggaaaaatgg tcactgacag cattggaggc
    26461 aaacttctaa ggaaaaaggc aacgaagcta gaaatggcag cgtgccaagg attggtaaat
    26521 tcttcatact caatcccata tttttcctct accagagcct tgagtggatt tttaagaaag
    26581 atcttattag tcaagagttg ggcagaagtt ttgaattctc cattttggat ataagaagca
    26641 tagagggatt ttttggctag ttccctatct tggtctagca agagtttttc tcgcgaaacg
    26701 gcagcttcct cggtatcttt tggagttgaa acggatacat attctccacc agccattgaa
    26761 aaggcaccag ctaagatagc cgcaaaacct gataaaaaga taatccagat attgctcgtg
    26821 gcactggcaa ctccgataac cacaccagca atggaaataa ttccatcgtt agcatcaaga
    26881 acacccgcac gcaggatatt taaacgacct gcaaaatttg aatcaatttc gtgatttgtt
    26941 tctgacgcta aatttcaagt tcaagttagc catccagaag tcttctctgg gtgacttgta
    27001 gtccaagcat tttttaggat agttgttaat ccacttttcg atgaatgcga cttctttggg
    27061 agtcattttc ttgattccct taggtaacca tctacgaatg agcctgttgt gattctcatt
    27121 agttcccctt tcccaagagg cataggggtg cgcataatag atgtgctcct cagaaaatac
    27181 atcaaataag cgattgaatt ccgttccatt atctgccgtg atggaaagaa tcttgtgttg
    27241 ttttaagatg agttttagag cctgattgac cacatcagca cttttatttg gaatcaatcg
    27301 gatgatctga tgtctactct ttcgatcagt caagacaagc aaacagtagt ttttcgctct
    27361 cgtaagtaga accgtatcaa tctcataatg cccattctcc aagcgaagat tgatagcttc
    27421 agaccgctgt tcgatggatt gaccagcagg tttaaagttg gtgctagcct gtttcttaag
    27481 cgcttttcct tttctagggt aaagcagatc ctgtttgctt aaccccaatt ttccatgatg
    27541 aatccaatag taaatggttg aaattcccac gttaacccct ttaaccatca ccatcatttc
    27601 aggcgaaaat ttttggttat gatagtggag aatcttttct tttagttcct tggtcacgct
    27661 tgatttcctg accgagcgct tgcgattgtt ttcataagac tgttgagcat agtcggcaga
    27721 ataaacctct ttgaagcgcc cttttccaag acattgtcgg actgtcccac gcttgatttc
    27781 agtgtggata gtttgaggaa cttttccaag cagagaggca atttctctat ttgatttccc
    27841 ttcttttttc catctttcga ttaagcgacg gctatcgatt gtcaaatgtt tggcttttgt
    27901 agtataattg tcttgcatct ctgtgccttt cttgtgtttg tggttgaaca acaagtataa
    27961 cacagaggtg ttttcttatg cctacaagag ctatcagcta gttgaaccat ctaattttta
    28021 ggagggctgg gtggctaact tcattataga actttcattt acgaacatat agtaaaatga
    28081 aacaagaaca gaacaaatcg atcaggacag taaaatctat ttctaataat gttttagaag
    28141 cagaagtgta ctattctagt ttcaatctac tatatttttg ttttttatca aaaaatactt
    28201 tacaagttct taaaaacatg atatagtaat aaagcttaga aaatgagatg atgttttcta
    28261 gcaaatataa acccgagtaa aaaatgccta cggacaggca gggttgaatg ccgaagcgtg
    28321 gttgaaaagc cacattattg atagggttaa aagcctactt ttataagttg atgttaggac
    28381 acttgtccta attcataaat ttttagtgtg gtgaaagcac acgtcatctt gtgaaacgat
    28441 caataaagta cgtaatattt gctactagag agttaggaaa catcgggaac agacatactc
    28501 aacagaaacc aaaataaaca cgtcagaaga ttgcagagca ggtgaaaacc tgctcttttt
    28561 tcatgagtca acctttagtt ccttagtttt cataaggtcc taaaaatatt gaaaggagta
    28621 tgttttgaaa gagttagatc aaaaccaagc cccaatttat gaagccttgg tgaagttacg
    28681 caagaaaagg attgttccct ttgatgttcc aggtcacaag cgtggacggg gaaatccaga
    28741 acttgtcgaa ctcttaggag aaaaatgtgt aggcattgat gtcaattcga tgaaaccctt
    28801 ggataattta ggccatccta tttcgattat tcgtgatgca gaggagctgg ctgcagatgc
    28861 ttttggagct agccatgcct ttctaatgat tggtggaaca acttcatcgg tgcagactat
    28921 gattctggca acctgcaagg caggagataa gattattctg ccacgaaatg tccataaatc
    28981 tgctatcaat gcgttggttc tatgtggtgc cattcccatc tatatcgaga tgagtgtaga
    29041 tcctaagatt ggtatcgctt taggtcttga aaatgaccga gtagcacagg ccataaagga
    29101 ccatccagat gctaaggcta tcctaatcaa caatcctact tactacggca tctgttcaga
    29161 cctaaagggg ttgacagaaa tggctcatga agctggcatg atggttttag tagatgaagc
    29221 ccatggagcg catttgcatt tcactggtaa acttccaatt tctgctatgg atgcaggagc
    29281 tgatatggca gcagtttcca tgcataagtc tggtgggagt ttgacacaaa gttcgcttct
    29341 tttaatcggg gagcagatga atcccgagta cgttcgtcag attataaacc tgacccagtc
    29401 tacatctgcc tcttacttat tgatggctag tttggatatt tcacgtcgca acttggccct
    29461 tcgtggtaaa gagtcgtttg aggaagtcat tgagctatcc gagtacgctc gtcatgaaat
    29521 caatgccatt ggcggttact atgcttactc aaaagagtta atagatggtg tgtcggtctg
    29581 tgattttgat gtaaccaagt tgtcagttta cactcaggga ataggcttaa caggtatcga
    29641 ggtttatgac ctcttgcgag acgaatacga cattcagatc gagtttggtg atatcggcaa
    29701 tatcttggcc tatatttcca tcggcgaccg catccaagac atcgagcgct tggttggtgc
    29761 tctggctgat attaagagac tctattcacg agatgggaag gacttaatag ctggagaata
    29821 tattcagccc gagttggtgc tgtctccaca agaagccttc tattcagaga gaaaaagttt
    29881 gaccttagat gagtctgttg gacaggtctg tggagaattt gtcatgtgct atcctccagg
    29941 gattcctatc ttggctcctg gtgaacgcat tacacgagaa attgtagact atatccaatt
    30001 cgccaaggaa cgtggttgct ccctccaagg gacggaagat ccagaggtca atcatatcaa
    30061 cgttattaag agaaagacaa actataagaa aagtcaatag ttttatctaa actatttctt
    30121 atttcaattt gatgatttgg cgatgatttt agagcacggc aaaaagccct tgaattagaa
    30181 gcggtcaatc gcttaatttc tatcagctta tcaaatcctg cctcaatcct tttctgagga
    30241 ttagggtagc gtgtcaagag ttggtaggta tattctgaat gctttccaac gattttatcc
    30301 aactcaggaa agatgatatc aagacaacga gtgtattgta ctttccaatc agactgtttt
    30361 tcttgagacg atgaatatgt ctagccagta tttttagttc tacttgccga ttatcgtgtt
    30421 gaaattgttc acgattgggg tcagaaagaa gtttaagagc gatgccatga gcgtctttct
    30481 tatccgtttt agtcttgcga agtgataatg atttggcaaa ttccttgatg agcaaaggat
    30541 tgtaggtgta aactttatat ccttgttcat gcaggaagtt cagtagatta aaggcataat
    30601 gtccagtatc ttcaagagcg atgagacagt cttggttgag ctgtcgaaga gacagatcta
    30661 agagttcaaa accagcttta ttatttgaaa aagtgagtgg tttaagaaca gtttttcctt
    30721 gaacattcaa ggctgtaaca tcgtgtttat ttttagcgat atcaatgccc acataaagca
    30781 tgggagtacc tccagatgta gtatttcaag tctacttggt tatccacgaa ctttttgcct
    30841 tgttacctta gacgagataa aacgtctatg cgttatcaaa ctcattacca attgaaacaa
    30901 aagctgtggt tagagccttt cggaaatcgt caagcgattg gaggaaatga actaatccac
    30961 agtggcttat tccaagtata ccacttgggc tttggcagta gctaactgcg ctaaatataa
    31021 tataaggaga aatagatgga tttatggttt tctgaagttc atactccaga tgtcaaattg
    31081 tctctgagaa cagccaagca actttacgct ggaaaaagtg aatggcagga tatcgaagtc
    31141 ttggatacgc cagcttttgg gaaaatactg attttaaatg gccatgtctt gttctcagat
    31201 gcggatgatt tcgtctacaa tgaaatgacc gttcacgttc ccatggctgt ccacccaaat
    31261 ccaaagaaag tattggttat tgggggtggt gacggcggtg ttgcccaagt attaacactc
    31321 tatcctgaac tggaacaaat cgatatcgtg gaaccggatg agatgttggt cgaggtctgt
    31381 cgtgagtatt tcccagactt tgctgcaggg ctagatgatc ctcgtgttac catttactac
    31441 caaaatgggc tacgcttttt gcgaaactgc gaagatgatt acgatattat catcaacgat
    31501 gcgacagatc catttggcca tacggaagga ctctttacca aggaattcta cggcaatagt
    31561 tatcgagctc tgaaggaaga cggcatcatg atttaccagc atgggagtcc cttctttgac
    31621 gaggatgagt cggcctgccg aagcatgcac cgcaaggtca atcaatcctt tccaatcagt
    31681 cgggtttatc aggcccatat tccaactagc ccagctggct attggttgtt tggatttgca
    31741 tcgaaaaaat accaccctgt caaagatttt gacaaggaag gttggaaaaa acgccagctt
    31801 ttcacagaat actacactgc aaacttacac gtgggagctt ttatgttgcc caagtatgtt
    31861 gaggacattt tagaagaaga ggaaggaaaa aaatgagtcg tttactagtt attggttgtg
    31921 ggggcgttgc ccaagttgct atttcaaaaa tttgtcaaga tagcgaaaca tttacagaga
    31981 ttatgattgc tagccgtacc aagtcaaaat gcgatgactt gaaagcgaag ctagaaggca
    32041 aaacaagtac taaaattgaa actgcagcac ttgatgctga caaggtagaa gaggtcatta
    32101 ccttgattga aagctacaaa ccagaagctg ttttgaatgt agctctgcct tatcaagatt
    32161 taaccattat ggatgcttgt ttggcaacag gtgttcacta tatcgataca gccaactacg
    32221 aagcagaaga cacagaagac cctgagtggc gtgctatcta cgaaaaacgt tgtaaggaac
    32281 ttggttttac agcctacttt gactactcat ggcagtgggc ttatcaagag aaattcaaag
    32341 aagcaggctt gactgctctt cttggttctg gttttgaccc aggtgtaact agtgtctttt
    32401 cagcttatgc cctcaaacac tattttgatg aaatccatta tatcgacatt ttagactgta
    32461 atggcggtga ccacggttat ccatttgcaa ccaactttaa tccagaaatt aatctccgtg
    32521 aggtttctgc gccaggttct tactgggaag atgggaaatg ggtcgaagtc gaagctatgt
    32581 ctatcaagcg tgagtatgat ttccctcaag ttggacaaaa agatatgtat ctccttcacc
    32641 atgaagaaat cgaatcattg gccaagaaca ttccaggtgt caaacgcatt cgtttcttta
    32701 tgacttttgg tcaatcttac ttgacgcaca tgaaatgtct tgaaaatgtt ggactccttc
    32761 gtacggatac cattaacttt aacggccaag aaattgttcc aattcaattt ttgaaagcct
    32821 tgcttccaga tcctgctagc cttggcccac gtacagtcgg aaaaaccaat attggatgta
    32881 tctttacagg tgtcaaagat ggcgttgaaa agactatcta catctacaat gtttgcgacc
    32941 atcaagagtg ctatgcagaa gtcgggtcac aagcaatttc atacacgaca ggcgttccag
    33001 ccatgattgg gacaaaatta gtcatgaacg gaacttggaa acaagctgga gtgtataacc
    33061 ttgaggagtt agatccagat ccattcatgg aagctttgaa tgagtatggt ttgccatggg
    33121 ttgtggttga aaatccacaa atggtggact aatgaagtta gaacaagtac caacaccagc
    33181 ctatgttatt gacttggcca agttagaagc taattgccgc attctacaat atgtacaaga
    33241 agaggccggt tgcaaggtct tgcttgccca gaaggcatat tccctctaca aaacttatcc
    33301 cttgattagc cagtatctat caggtacgac agctagtgga ctctatgagg ccaaattggc
    33361 aagggaagaa tttcctggtg aagtccatgt atttgcgcct gctttcaagg atgcagactt
    33421 ggaggaattg cttgggataa cagaccatat cgtctttaac tcagagagac agttgcgtaa
    33481 gcatggggct cgttgtcgag aggctggtgt cagtgttggt ttgcgcctca accctcagtg
    33541 ttcaactcaa ggagatcacg cgctctatga cccttgtgca ccaggttctc gctttggagt
    33601 tactatagac aagattccga gtgatttgct agatttggtt gacggacttc attttcatac
    33661 cctttgcgag cagggagcag atgatttaca aacaactttg aaagcagtag aagaacaatt
    33721 tggtccctac ttacatgagg taaaatggct caatatgggt ggtggtcatc atattacaag
    33781 agaaggttac gatgtggatt tgctgatttc agaaatcaag cgtatccgaa aaacttacaa
    33841 tcttgaaatc tatatcgagc ctggtgaagc cattgcgctt aatgcgggtt atttagcaac
    33901 tgaggtatta gatattgtag aaaacggtat ggaaatcttg gttttagacg cctctgcgac
    33961 ctgccatatg cctgatgtac ttgagatgcc ctatcgtcca cctttgagaa atggctttga
    34021 ggcacaggaa aaagcccata cctacagact ttcttctaat acctgtctga cgggcgatgt
    34081 gattggtgat tatagttttg aaaatccagt ccaaatcgga gacagacttt attttcaaga
    34141 catggccatt tattcttttg tcaaaaataa tacctttaat ggtattggat tgccaagtct
    34201 ctatctcatg gacgaacagg gagactgtag cttactcaaa gcttttggct atcaagactt
    34261 taaagggaga ttatcatgat ggacagtcca aaaaaattag gctatcacat gccagcagag
    34321 tacgaacccc atcatggtac cctcatgata tggccgactc gaccaggatc atggcctttt
    34381 caaggaaagg ctgctaaaag atcatttact cagatcatcg agaccatagc agaaggggaa
    34441 agagtctatc ttttggtgga gcaggcctat ctatctgaag cccaatccta tcttggagac
    34501 aaggttgttt atttagacat tcccaccaat gatgcctggg cgcgtgatac tggcccaacc
    34561 attctcgtca atgataaagg taagaaatta gccgtggatt gggccttcaa tgcttgggga
    34621 ggcacctatg atggtcttta tcaagattat gaagaggatg accaagtagc cagtcgtttt
    34681 gctgaggcct tgggaaagcc tgtctatgat gctaaacctt ttgtactgga aggaggcgca
    34741 atccatagcg atggtcaagg aactattctc gtaactgaaa gttgcttgct tagtcctggt
    34801 cgcaatccta acctgactaa agaggagatt gaaaacacat tattagaaag tcttggtgct
    34861 gaaaaagtta tttggcttcc ttatggtatt tatcaggatg aaaccaatga acacgtcgat
    34921 aatgttgctg cctttgttgg tcctgctgag gttgttttag cttggacaga tgacgaaaat
    34981 gatccccagt atgccatgtc aaaagcagat ctcgaactct tagaacagga aacagatgca
    35041 aaaggttgtc acttcaccat tcataaattg cctatccctg cagttcgaca agttgtgaca
    35101 gaagaagatt tgccaggcta catctatgaa gaaggagaag aaaagcgata cgcaggtgaa
    35161 cgactagcag cttcctacgt aaacttttat atcgccaaca aggctgtctt ggttccacag
    35221 tttgaggatg taaacgacca agtggcctta gatatcctca gcaagtgttt cccagaccgt
    35281 aaagttgtcg gaataccagc cagagatatt ctcttaggtg gtggcaatat ccactgtatc
    35341 acccaacaaa ttccagaata ggagaaaaag atgagaaatg taagagttgc aaccattcag
    35401 atgcaatgcg ctaaggatgt ggcaacaaat atccaaaccg cagagcgttt agtacgtcag
    35461 gctgctgagc aaggagccca aattattctc ttgcccgagt tgtttgaaca tccctatttc
    35521 tgtcaggaac gtcagtatga ctactaccag tatgcccaat ctgtagcgga aaatactgcc
    35581 attcagcatt ttaaggtgat tgctaaggaa ctacaagttg ttttaccaat cagtttctat
    35641 gaaaaagatg gtaatgtctt gtataactct attgccgtca ttgatgcaga tggggaagtg
    35701 ctgggcgttt atcgaaagac ccacatacca gatgaccatt attatcaaga aaaattctat
    35761 ttcacgcctg gtaacactgg tttcaaggtc tggaatactc gctatgctaa gattggtatc
    35821 ggtatctgtt gggatcaatg gttccctgaa acagcgcgct gtcttgcatt gaatggtgct
    35881 gaattgctct tttatcctac agctatcggt tcagagccaa ttttggatac agatagttgt
    35941 ggtcactggc aacgtactat gcaagggcac gcagcagcga atattgttcc agtcatcgca
    36001 gccaatcgtt atggtttaga ggaggttact cctagtgagg aaaatggcgg acagagttcc
    36061 agtcttgact tctacggttc ctcctttatg acggatgaaa caggagctat tctagaacga
    36121 gctgaaagac aagaagaagc tgttctgtta gctacttatg acctagacaa gggagcaagt
    36181 gaacgcctaa actggggctt gtttcgagat agaagaccag aaatgtatag acaaattaca
    36241 gattagtgtg ggagaaatga gagattcatt ctgctagact aacttcttat tagcaactat
    36301 aagatactat ggcatctagt aaatcgattt ttatgattcg ctattcttgt ctattgatta
    36361 gtccgtattt taaaatatta gcaaaaaagc aaatagcagt aacttctgtc tatttgcttt
    36421 tcttttttat agaatatatt tctcaatagc acgcgcaacg ccgtcttctt cgttgcttga
    36481 ggtaacggca tccgcaagag atttgacata atcgctggca tttcccattg caatcccaag
    36541 ccctgcaaac tggagcattt cgatatcgtt attagcatcg cccatggcca taatctctga
    36601 ggaatcaatc ttcaaaatct cagctagtcg tgaaatagca gtagcctttg tcgttccaag
    36661 cggcattgct tcataaatga caggctgcga acgaactcca ctgaatcgtt ggcaaagctc
    36721 ttcagcaaaa cgctgctcaa aatcgtctgt ttgttctttt gttcctaaaa acataccttg
    36781 gaacatccgg aactttccac tagtcgcttc ttcaagagaa atttcagtca ggtctgaaaa
    36841 tactagttta gcatcatttt caataacttg attgggtttg ccaccgagaa caaaataatg
    36901 tgactcgtca aaaagtgtca actgaacatc actcttttca gcaaggtcat agaggtattc
    36961 gatgtcagct ggactcagtt ctttccagtc aactagactc caatcactgg tctggtgagt
    37021 tgaacaaccg ttgttaacaa taatatattc gttctggagg tcgagtccca gttttttgta
    37081 gtaggggagg acaccgaaaa gggggcgacc cgtacagaga accagtttga cacctttttc
    37141 aatggctttg tgaatagcag taatgtgagc ttgtgggatt tccttggctt cattgaggag
    37201 ggtgccgtcc atatccaagg ctagtagttt aatcataggt cttccttctt tatcttttgc
    37261 tattattata gcatattttg gagaagaaat tgatagaaag cttgagacta attgatttta
    37321 tagtttaaga tgttttgatg acaattcatg atttgaagag gatatttggc aaagatatgc
    37381 tatactatgt ttgtcaatgt tgcaactaga caaattaaaa aaccaactta atataatagt
    37441 ttttttgtaa gtaggtatga gtatcagatt actcaactaa tctgaagaat aatggaggaa
    37501 atatatcatg attttaatga caaaaaatat aaatctaaca aatgaagaat tagagctgat
    37561 acaaggtgga gcagatccct atggtaaaga acctaatggt tattatcctt ggcaaatgga
    37621 accagtatta actatgccgg ttcatggatt ttgtcccaga ggaaccgatg atttaggata
    37681 tattggagga ggtaatcatc tttgcaaagg aagtgctgcg agattttaag taaaatttat
    37741 taggaatatg aagaaacaag gggagaaaac agaggattta atatgaaaaa acgagctatt
    37801 caaattttac tagtattgtc cttaattttt tacaaatcaa cttggttttg gaggcttttc
    37861 aattatctcg caaagcccta tctaccagca agtcgtgaat tttttcagat tctgcttttg
    37921 atggagagtg gagttctttt attagcggtc atctatctac tggtttttgc aggaaagaaa
    37981 atttttcatt tcaagtggca gctgaggtat tttatctacc ttttactggg ttacatcact
    38041 tcgtatatgt ctgactttct cttttcgtat ttcatatctc tgtcttcaaa tcagatttct
    38101 ttgaatgaaa cggtagaaat gatggggaga caggagttcc cttatttctt gctcatcgtt
    38161 tgcttcatcg cccctattgc tgaggaattg atttatcgag gtgtgcttat gacaaccttt
    38221 ttcaaaaact caccttggta cggagatgtt ttgctttctg ctattatttt cggttatatt
    38281 catatcaatt ttgctttaac tcctcttgct tttttcattt atgctagtgg aggtcttatt
    38341 ttagctctat tgtatcgcat gactaaaaat ctctactatc caatactagt tcatattctc
    38401 atcaatatca ctgccttctg ggatgtttgg ttactcctat tttcaggaag ttagcttact
    38461 aaaaaaatgt cggaattttc cggcattttc ttttttcaca aatagtcaac gtttttcttt
    38521 ccgatactga agtggtgtgt agccacttat ttttttgaat tgattttgaa aataagattg
    38581 gcgtaagaaa ggcagatagt gaagatagtt aagaagaata ggatgttctt ttttcctttt
    38641 tggaaaactt ctaaaatatg gtataatgaa aagataaaga agttgggggt agaagatgaa
    38701 cattcaacaa ttacgctatg ttgtggctat tgccaatagt ggtacttttc gtgaagctgc
    38761 tgaaaagatg tatgttagtc agccgagtct gtctatttct gttcgtgatt tggaaaaaga
    38821 gttgggcttt aagattttcc gtcggaccag ctcagggact ttcttgaccc gtcgtgggat
    38881 ggaattttat gaaaaagcgc aagaattggt taaaggattt gatatttttc aaaatcagta
    38941 tgccaatcct gaagaagaaa aagatgaatt ttccgttgct agccagcact atgacttctt
    39001 gccaccaact attacggcct tttcagagcg ctatcctgac tataagaact tccgtatttt
    39061 tgaatcaact actgttcaaa tattagatga agtggcgcaa gggcatagtg agattgggat
    39121 tatctacctc aacaatcaaa ataaaaaggg gattatgcaa cgggttgaaa aattaggtct
    39181 ggaggtcatc gaattgattc ctttccatac ccatatttat ctccgtgagg gtcatccttt
    39241 agcccagaaa gaggaattag tcatggagga tttagcggat ttaccaacgg ttcgtttcac
    39301 tcaagagaaa gacgagtacc tttattattc agagaacttt gtcgatacca gcgctagctc
    39361 acagatgttt aatgtgacag accgtgccac cttgaatggt attttggagc ggacggacgc
    39421 ctatgcgaca ggttctggat ttttagatag tgacagtgtt aatggcatta cagttattcg
    39481 tctcaaggat aacctagata accgcatggt ctatgttaaa cgtgaagaag tggagcttag
    39541 tcaagctggg actctcttcg tagaagtcat gcaagaatat tttgatcaaa agaggaaatc
    39601 atgaaaaaaa gagcaatagt ggcagtcatt gtactgcttt taattgggct ggatcagttg
    39661 gtcaaatcct atatcgtcca gcagattcca ctgggtgaag tgcgctcctg gattcccaat
    39721 ttcgttagct tgacctacct gcaaaatcga ggtgcagcct tttctatctt acaagatcag
    39781 cagctgttat tcgctgtcat tactctggtt gtcgtgatag gtgccatttg gtatttacat
    39841 aaacacatgg aggactcatt ctggatggtc ttgggtttga ctctaataat cgcgggtggt
    39901 cttggaaact ttattgacag ggtcagtcag ggctttgttg tggatatgtt ccaccttgac
    39961 tttatcaact ttgcaatttt caatgtggca gatagctatc tgacggttgg agtgattatt
    40021 ttattgattg caatgctaaa agaggaaata aatggaaatt aaaattgaaa ctggtggtct
    40081 gcgtttggat aaggctttgt cagatttgtc agaattatca cgtagtctcg cgaatgaaca
    40141 aattaaatca ggccaggtct tggtcaatgg tcaagtcaag aaagctaaat acacagtcca
    40201 agagggtgat gtcgtcactt accatgtgcc agaaccagag gtattagagt atgtggctga
    40261 ggatcttccg ctagaaatag tctaccaaga tgaggatgtg gctgtcgtta acaaacctca
    40321 gggaatggtt gtgcacccga gtgctggtca taccagtgga accctagtca atgccctcat
    40381 gtatcatatt aaggacttgt cgggtatcaa tggggttctg cgtccaggga ttgttcaccg
    40441 tattgataag gatacgtcag gtcttctcat gattgctaaa aacgatgatg cgcatctagt
    40501 acttgcccaa gaactcaaag ataaaaagtc tctccgcaaa tattgggcga ttgttcatgg
    40561 aaatctgcct aatgatcgtg gtgtaattga agcgccgatt ggccggagtg aaaaagaccg
    40621 taagaaacag gctgtaactg ctaaagggaa gcctgcagtg acgcgttttc acgtcttgga
    40681 acgctttggc gattatagct tagtagagtt gcaactggag acagggcgta ctcatcaaat
    40741 ccgtgtccac atggcttata tcggccatcc agtcgctggt gatgaggtct atggtcctcg
    40801 caagactttg aaaggacatg gacaatttct tcatgccaag actttaggtt ttactcatcc
    40861 gagaacaggt aagaccttgg aatttaaagc agatatccca gagattttta aggaaacctt
    40921 ggagagattg agaaagtaag aatgaaaaag aaattaacta gtttagcact tgtaggcgct
    40981 tttttaggtt tgtcatggta tgggaatgtt caggctcaag aaagttcagg aaataaaatc
    41041 cactttatca atgttcaaga aggtggcagt gatgcgatta ttcttgaaag caatggacat
    41101 tttgccatgg tggatacagg agaagattat gatttcccag atggaagtga ttctcgctat
    41161 ccatggagag aaggaattga aacgtcttat aagcatgttc taacagaccg tgtctttcgt
    41221 cgtttgaagg aattgggtgt ccaaaaactt gattttattt tggtgaccca tacccacagt
    41281 gatcatattg gaaatgttga tgaattactg tctacctatc cagttgaccg agtctatctt
    41341 aaaaaatata gtgataatcg tattactaat tttgaacgtc tatgggataa tctgtacggt
    41401 tatgataagg ttttacagac tgcttcagaa aaaggtgttt cagttattca aaacatcaca
    41461 cagggagatg ctcattttca gtttggggac atggatattc aactctataa ctatgaaaat
    41521 gaaaccgatt catcaggtga attaaagaaa atttgggatg ataattccaa ttccttgatt
    41581 agtgtggtaa aagtcaatgg caagaaaatt taccttgggg gcgacttaga taatgttcat
    41641 ggagcagaag acaagtatgg tcctctcatt ggaaaagttg atttgatgaa gtttaatcat
    41701 caccatgata ccaacaaatc aaataccaag gatttcatta aaaatttgag tccgagtttg
    41761 attgttcaaa cttcggatag tctaccttgg aaaaatggtg ttgatagtga gtatgttaat
    41821 tggctcaaag aacgaggaat tgagagaatc aacgcagcca gcaaagacta tgatgcgaca
    41881 gtttttgata ttcgaaaaga cggttttgtc aatatttcaa catcctacaa gcctattcca
    41941 agttttcaag ctggttggca taagagttca tatggaaact ggtggtatca agcgcctgat
    42001 tctacaggag aatatgctgt cggttggaat gaaattaagg gtgaatggta ttactttaac
    42061 caaacgggta tcttgttaca gaatcaatgg aaaaaatgga acaatcgttg gttctatttg
    42121 acagactctg gtgttgctgc taaaaattgg aagaaaattg ttggaatctg gtattatttt
    42181 aacaaagaaa accagatgga aattggttgg attcaagata aagagcagtg gtattatttg
    42241 gatgttgatg gttctatgaa gacaggatgg cttcaatata tggggcaatg gtattacttt
    42301 gctccatcag gggaaatgaa aatgggctgg gtaaaagata aagaaacctg gtactatatg
    42361 gattctactg gtgtcatgaa gacaggtgag atagaagttg ctggacatca ttactatcta
    42421 gaagaatcag gagctatgaa gcaaggctgg cttaaaaagg caaatgattg gtatttctac
    42481 aagacagatg gttcacgagc tataggttgg attaaagaca aggataaatg gtacttcttg
    42541 aaagaaaatg gtcaattact tgtgaatggt aagacaccag aaggctatac tgtggattca
    42601 agtggtgcct ggttagtgga tgttccgatc gagaaatctg ctacaattaa aactacaagt
    42661 cattcagaaa taaaagaatc caaagaagta gtgaaaaagg atcttgaaaa taaagaaacg
    42721 agtcaacatg aaagtgttac aaattcttca actagtcaag atttgacatc ctcaacttca
    42781 caaagctctg aaacgagtgt aaacaaatcg gaatcagaac agtagtagaa aagaaggttt
    42841 tagggccttc tttttcctat caactctttt ctatttcctg ttattcatgt tataatggat
    42901 aaatatgaat aatcggagtg agactatgaa atacaaacgg attgtcttta aggtgggtac
    42961 ttcttctctg acaaatgagg atggaagttt atcacgtagt aaggtaaagg atattaccca
    43021 gcagttggct atgctgcacg aggctggtca tgagttgatt ttggtgtctt caggtgccat
    43081 tgcggctggt tttggagcct taggatttaa aaagcgtccg actaaaattg ctgataaaca
    43141 ggcttcagca gcggtagggc agggactttt gttggaagaa tatacgacca atcttctctt
    43201 gcgtcaaatc gtttctgcac aaatcttgct gacccaagat gactttgtgg ataagcgtcg
    43261 ttataaaaat gcccatcagg ctttgtcggt tttgctcaac cgtggggcaa ttcctatcat
    43321 aaatgagaat gatagtgtcg ttattgatga gctcaaggtt ggggacaatg acactctaag
    43381 tgctcaagta gcggcgatgg tccaagcaga ccttttagtt ttcttgacag atgtggacgg
    43441 tctctatact ggaaatccta attcagatcc aagagccaaa cgcttggaga gaatcgagac
    43501 catcaatcgt gagattattg atatggctgg tggagcaggt tcgtcaaacg gaactggggg
    43561 tatgttaacc aaaatcaagg ctgcaactat cgcgacggaa tcaggagttc ctgtttatat
    43621 ctgctcatcc ttgaaatcag attccatgat tgaggcggca gaggagactg aggatggttc
    43681 ttactttgtt gctcaagaga aggggcttcg tacccagaaa caatggcttg ccttctatgc
    43741 tcagagtcaa ggttctattt gggttgataa aggggctgcg gaagctctct ctcaacatgg
    43801 aaagagtctt ctcttatctg gtatcgttga agcagaagga gccttttctt acggtgatat
    43861 cgtgacagta tttgacaagg aaagtggaaa atcacttgga aaaggacgcg tgcaatttgg
    43921 agcatctgct ttggaggata tgttgcgttc tcaaaaagcc aagggtgtct tgatttaccg
    43981 tgacgactgg atttccatta ctcctgaaat ccaactactt tttacagaat tttagaggta
    44041 aactatggtg agtagacaag aacaatttga acaggtacag gctgttaaaa aatcgattaa
    44101 cacagctagt gaagaagtga aaaaccaagc cttgctagcc atggctgatc acttagtggc
    44161 tgctactgag gaaattttag cggctaatgc cctcgatatg gcagcggcta aggggaaaat
    44221 ctcagatgtg atgttggatc gtctttattt ggatgcagat cggatagaag cgatggcaag
    44281 aggaattcgt gaagtggttg ccttaccaga tccaatcggt gaagttttag aaacaagtca
    44341 gcttgaaaat ggtttggtta tcacaaaaaa acgtgtagct atgggtgtca tcggtattat
    44401 ctatgaaagc cgtccaaatg tgacgtctga tgcggctgct ttgactctta agagtggaaa
    44461 tgcggttgtt cttcgtagtg gtaaggatgc ctatcaaaca acccatgcca ttgtcacagc
    44521 cttgaagaag ggcttggaga cgactactat tcatccaaat gtgattcaac tggtggagga
    44581 tactagccgt gaaagtagtt atgctatgat gaaggccaag ggctatctag accttctcat
    44641 tcctcgtgga ggagctggct tgatcaatgc agtggttgag aatgcgattg tacctgttat
    44701 cgagacaggg actgggattg tccatgtcta tgtggataag gatgcagacg aagacaaggc
    44761 gctgtctatc atcaacaatg ctaaaaccag tcgtccttct gtttgtaatg ccatggaggt
    44821 tctgctggtt catgaaaaca aggcagtaag cttccttcct cgcttggagc aagtgttggt
    44881 tgcagatcga aaagaagctg ggttggaacc aattcaattc cgcctagata gcaaagcaag
    44941 ccagtttgtt tcaggtcaag ctgctcaagc acaagacttt gataccgagt ttttagacta
    45001 tattctagct gttaaggttg tgagcagttt agaagaagcg gttgcgcata ttgaatccca
    45061 cagtacccat cattcggatg ccattgtgac ggaaaatgct gaagctgcag catactttac
    45121 agatcaagtg gactctgcag cggtgtatgt taatgcctca actcgtttca cagatggagg
    45181 acaatttggt cttggttgtg aaatggggat ttctactcag aaattgcacg cgcgtggtcc
    45241 tatgggcttg aaggaattga ctagctacaa gtatgtggtc actggtgatg gacagataag
    45301 ggagtaagag atgaagattg gatttatcgg tttggggaat atgggtgcta gtttagccaa
    45361 gtctgtcttg caggctagac cgtcagatga gattctcctt gccaatcgta gtcaagtcaa
    45421 ggtggatgct ttcatcgcta acttcggtgg tcagacttct aacaatgaag aaatattcga
    45481 agaagcagat gtgatttttc taggtgttaa gcctgctcag ttttctgaac tgctttctca
    45541 ataccagacc atccttgaaa aaagagaaag tcttcttttg atttcgatgg cagctggatt
    45601 gatcttagaa aaactagcaa gtcttatccc aagccaacac cgaattattc gtatgatgcc
    45661 taatacccct gcttctatcg ggcaaggagt gattagttat gccttgtctc ctaattgcag
    45721 ggctgaggac agtgagctct tttgtcagct tttatccaag gctggtctct tggttgaatt
    45781 aggagaaagt ttaatcaatg cagcgacagg tcttgcaggc tgtggaccag cctttgtcta
    45841 tctctttatt gaggccttgg cagatgcagg tgttcagacg ggattaccac gagaaacagc
    45901 cttgaaaatg gcagcccaaa ctgtggtagg agctgggcaa ttggtcctag aaagccagca
    45961 acatcctgga gttttgaaag atcaagtttg tagtccaggc ggttcgacta ttgctggcgt
    46021 agcaagccta gaagcgcatg cttttcgagg aacggtcatg gaggcagttc atcaagccta
    46081 taaacgaaca caagaactag gtaaataaga ggtagtttta tctgcctctt ttatggtggt
    46141 tgatactctt cgaaaatcaa attcaaactg cgtcagcttc accttgccgt actcaagtac
    46201 agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtatgaa atgagaagac
    46261 aaaaagattg tcacaaaccc ctattttttt gatagaatag aagtagtaaa aaagaaatga
    46321 gttagacatg tcaaaaggat ttttagtctc tcttgaggga ccagagggag caggcaagac
    46381 cagtgtttta gaggctctgc taccaatttt agaggaaaaa ggagtaaagg tgctgacgac
    46441 ccgtgaacct ggcggagtct tgattgggga gaagattcgg gaagtgattt tggatccaag
    46501 tcatactcag atggatgcta aaacagagct acttctctat attgccagtc gcagacagca
    46561 tttggtggaa aaagttcttc cagcccttga agctggcaag ttggtcatca tggatcgttt
    46621 tatcgatagt tctgttgcct atcagggatt tggtcgtggc ttagatattg aagccattga
    46681 ctggctcaat cagtttgcga cagatggcct caaacccgat ttgacactct attttgacat
    46741 cgaggtggaa gaagggctgg ctcgcattgc tgcgaatagt gaccgcgagg tcaatcgtct
    46801 ggacttggaa ggtttggaat tgcacaagaa agtccgtcaa ggctaccttt ctctcctgga
    46861 aaaagaagga aatcgcattg tcaagattga tgctagtctc cctttggagc aagttgtgga
    46921 aactaccaag gctgtcttgt ttgacggaat ggacttggcc aaatgaaaca agatcaacta
    46981 aaggcttggc aaccagctca gtttgaccgt tttgtccgta tcttagaaca agaccagctc
    47041 aatcacgcct atctcttttc aggtttcttt ggaagcttgg aaatggcgca atttttagct
    47101 aagagcctct tttgtacgga taaagttggc gtcttaccat gtgagaaatg ccgaagttgc
    47161 aagctgattg aacaggaaga gtttccagat gtcaccttga ttaagccagt caatcaggtc
    47221 atcaagacag aacgcattcg ggaattggtg ggacagtttt ctcaagcagg gattgaaagc
    47281 cagcaacagg tctttattat cgagcaagcg gataaaatgc atcccaacgc agccaattct
    47341 ctgctcaagg tcatcgaaga accccagagt gaagtttata ttttcttctt gactagcgat
    47401 gaggaaaaga tgttaccgac aatccgaagt cggactcaga tcttccactt taaaaagcaa
    47461 gaagaaaaac ttatcttact cttagaacaa atgggacttg ttaagaaaaa agcgactctt
    47521 ttagctaagt ttagtcaatc gcgagctgaa gcagaaaagt tggcacatca ggcaagtttt
    47581 tggaccttgg tcgatgaaag tgaacgcctg ctgacttggt tagtagctaa gaaaaaagaa
    47641 agttatctac aggttgccaa attagccaac ttggcagatg ataaggaaaa acaggatcag
    47701 gttttacgga ttcttgaagt tctctgtggg caggacctct tgcaggtaag agtaagagtg
    47761 attctacaag atttactaga agctagaaaa atgtggcaag ctaatgtcag ctttcaaaat
    47821 gccatggaat atctggtctt gaaagaaata taaactcaaa aatgaatgat aaagaaagga
    47881 aagggctgtt ttatggacaa aaaagaatta tttgacgcgc tggatgattt ttcccaacag
    47941 ttattggtaa ccttggccga tgtggaagcc atcaagaaaa atctcaagag cctggtagag
    48001 gaaaatacag ctcttcgttt ggaaaattct aagttgcgag aacgcttggg tgaggtggaa
    48061 gcagatgctc ctgtcaaggc caagcatgtt cgtgaaagtg tccgtcgcat ttaccgtgat
    48121 ggatttcacg tatgtaatga tttttatgga caacgtcgag agcaggacga ggaatgtatg
    48181 ttttgtgacg agttgctata cagggagtag gcatgcagat tcaaaaaagt tttaaggggc
    48241 agtctcccta tggcaagctg tatctagtgg caacgccgat tggcaatcta gatgatatga
    48301 cttttcgtgc tatccagacc ttgaaagaag tggactggat tgctgctgag gatacgcgca
    48361 atacagggct tttgctcaag cattttgaca tttccaccaa gcagatcagt tttcatgagc
    48421 acaatgccaa ggaaaaaatt cctgatttga ttggtttctt gaaagcaggg caaagtattg
    48481 ctcaggtctc tgatgccggt ttgcctagca tttcagaccc tggtcatgat ttagttaagg
    48541 cagctattga ggaagaaatt gcagttgtga cagttccagg tgcctctgca ggaatttctg
    48601 ccttgattgc cagtggttta gcgccacagc cacatatctt ttacggtttt ttaccgagaa
    48661 aatcaggtca gcagaagcaa ttttttggct tgaaaaaaga ttatcctgaa acacagattt
    48721 tttatgaatc acctcatcgt gtagcagaca cgttggaaaa tatgttagaa gtctacggtg
    48781 accgctccgt tgtcttggtc agggaattga ccaaaatcta tgaagaatac caacgaggta
    48841 ctatctctga gttattagaa agcattgctg aaacgccact caagggcgaa tgtcttctca
    48901 ttgttgaggg tgccagtcag ggtgtggagg aaaaggacga ggaagacttg ttcgtagaaa
    48961 ttcaaacccg catccagcaa ggtgtgaaga aaaaccaagc tatcaaggaa gtcgctaaga
    49021 tttaccagtg gaataaaagt cagctctacg ctgcctacca cgactgggaa gaaaaacaat
    49081 aaagggagac aggatgtaat aattctgtct gtttctgttt aacttaatta gtgatgataa
    49141 tataaagatg tatcacttgg tatagaagct ttggtattaa gttttttatt aagcccatac
    49201 ggaataccga tggttggagc agcagttata gcgttcttag aaggtataaa tagaaaaata
    49261 aggtcatttt aaatcaaagg attgataaat cagaaagaag gtgatttttt gcgaacatac
    49321 gaaaataaag aagaactaaa agctgagata gagaaaacat ttgagaaata tattttagaa
    49381 tttgataata ttccagaaaa tttaaaagat aagagagctg atgaagttga cagaactcca
    49441 gcagaaaacc ttgcttatca ggttggttgg accaacttgg ttcttaaatg ggaagaagat
    49501 gaaagaaagg ggcttcaagt aaaaacacca tcggataaat ttaaatggaa tcaacttggt
    49561 gaattatatc agtggttcac agatacctac gctcatttat ctctgcaaga gttgaaagca
    49621 aaattaaatg aaaatattca ttctatctct gcaatgattg attcgttgag tgaggaagaa
    49681 ttatttgaac cgcatatgag aaagtgggct gatgaagcga ctaaaacagc gacttgggaa
    49741 gtgtataagt ttattcatgt aaatacggtt gcaccttttg gaactttcag aactaaaatc
    49801 agaaaatgga agaagatagt attataaatt atatttttaa ctttaaaaaa tttcataaaa
    49861 atggttacca aaggcgatag aagaaaaact atcgtctttt tctttgcaaa tttttaagaa
    49921 gggaggtgat cttgcatgga ctttgaatat ttttataaca gagaagcgga aagatttaac
    49981 ttcttaaaag taccggagat attagttgat agagaagaat ttcggggctt atcagcagaa
    50041 gcaattatcc tttattccat acttcttaaa cagacaggaa tgtcatttaa gaataactgg
    50101 atagacaagg aaggcagagt atttatctat tttactgtcg aagaaattat gaaaagaaga
    50161 aatatctcaa agccaactgc cataaaaaca ttagatgagc ttgatgtaaa aaaaggaata
    50221 ggactgatcg aaagagtaag gcttggactt ggtaagccga acatcattta tgttaaagac
    50281 tttatgagta tatttcaggt aaaagaaaat gacttacaga agtcaaaaaa cttaacttca
    50341 gaagtaaaag attttaacct cagaagtaaa gaaaatgaac ttcaagaggt taagaacctt
    50401 gactctaact atatagagaa taataagagt aagtatagta agagagaata tagttttggt
    50461 gaaaacggac ttggaacatt tcaaaatgtg tttttagctg ctgaagatat atcggattta
    50521 caaatcataa tgaactcaca gcttgagaat tacattagac ttcctgcaaa aatagaatcc
    50581 tagttcatga ttgataatac cagcaatcaa attcattcgt aatccgaagc gtttacgatg
    50641 atttcgatag gttgttgaaa acattttaaa cgtttttact ttggcaaaga tgttctcaac
    50701 cttgcttctc tccttagata gcgcatggtt taagccttat cttcaact
//
LOCUS       DAVEHY010000014        50198 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVEHY010000014 DAVEHY010000000
VERSION     DAVEHY010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50198
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.014"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(188..2011)
                     /locus_tag="VUZ44_000950"
     CDS             complement(188..2011)
                     /locus_tag="VUZ44_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU0319890.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRVIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            complement(1998..2363)
                     /locus_tag="VUZ44_000951"
     CDS             complement(1998..2363)
                     /locus_tag="VUZ44_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU0319891.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLISGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            complement(2368..2724)
                     /locus_tag="VUZ44_000952"
     CDS             complement(2368..2724)
                     /locus_tag="VUZ44_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319892.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            complement(3556..4713)
                     /locus_tag="VUZ44_000953"
     CDS             complement(3556..4713)
                     /locus_tag="VUZ44_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319893.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LLGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNTTIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(4741..5502)
                     /locus_tag="VUZ44_000954"
     CDS             complement(4741..5502)
                     /locus_tag="VUZ44_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PezT"
                     /protein_id="HEU0319894.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(5502..5978)
                     /locus_tag="VUZ44_000955"
     CDS             complement(5502..5978)
                     /locus_tag="VUZ44_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319895.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(6423..6878)
                     /locus_tag="VUZ44_000956"
     CDS             complement(6423..6878)
                     /locus_tag="VUZ44_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319896.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(7153..8892)
                     /locus_tag="VUZ44_000957"
                     /pseudo
     CDS             complement(7153..8892)
                     /locus_tag="VUZ44_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(9055..9939)
                     /locus_tag="VUZ44_000958"
     CDS             complement(9055..9939)
                     /locus_tag="VUZ44_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU0319897.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDDYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(10051..10905)
                     /locus_tag="VUZ44_000959"
     CDS             complement(10051..10905)
                     /locus_tag="VUZ44_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU0319898.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(10963..11721)
                     /locus_tag="VUZ44_000960"
     CDS             complement(10963..11721)
                     /locus_tag="VUZ44_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU0319899.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTYDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(11783..11971)
                     /locus_tag="VUZ44_000961"
     CDS             complement(11783..11971)
                     /locus_tag="VUZ44_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU0319900.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(12293..12859)
                     /locus_tag="VUZ44_000962"
     CDS             complement(12293..12859)
                     /locus_tag="VUZ44_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319901.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(13127..14806)
                     /locus_tag="VUZ44_000963"
     CDS             complement(13127..14806)
                     /locus_tag="VUZ44_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU0319902.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGYKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            complement(14898..15059)
                     /locus_tag="VUZ44_000964"
     CDS             complement(14898..15059)
                     /locus_tag="VUZ44_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319903.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(15659..16393)
                     /locus_tag="VUZ44_000965"
     CDS             complement(15659..16393)
                     /locus_tag="VUZ44_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU0319904.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEIDKEIEIDKEREGEIDK
                     KSTPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILK
                     WYEEDKDKLRQKGLNKKMNYDVGESL"
     gene            complement(16520..17047)
                     /locus_tag="VUZ44_000966"
     CDS             complement(16520..17047)
                     /locus_tag="VUZ44_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEU0319905.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(17233..17406)
                     /locus_tag="VUZ44_000967"
     CDS             complement(17233..17406)
                     /locus_tag="VUZ44_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319906.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            complement(17732..19119)
                     /locus_tag="VUZ44_000968"
                     /pseudo
     CDS             complement(17732..19119)
                     /locus_tag="VUZ44_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785367.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
     gene            complement(19433..19765)
                     /locus_tag="VUZ44_000969"
     CDS             complement(19433..19765)
                     /locus_tag="VUZ44_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU0319907.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVE
                     KSSKDEIT"
     gene            complement(19821..20246)
                     /locus_tag="VUZ44_000970"
     CDS             complement(19821..20246)
                     /locus_tag="VUZ44_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU0319908.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(20634..21428)
                     /locus_tag="VUZ44_000971"
     CDS             complement(20634..21428)
                     /locus_tag="VUZ44_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0319909.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(21428..22435)
                     /locus_tag="VUZ44_000972"
     CDS             complement(21428..22435)
                     /locus_tag="VUZ44_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU0319910.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(22435..23442)
                     /locus_tag="VUZ44_000973"
     CDS             complement(22435..23442)
                     /locus_tag="VUZ44_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU0319911.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(23432..24457)
                     /locus_tag="VUZ44_000974"
     CDS             complement(23432..24457)
                     /locus_tag="VUZ44_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU0319912.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(24850..25068)
                     /locus_tag="VUZ44_000975"
     CDS             complement(24850..25068)
                     /locus_tag="VUZ44_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0319913.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(25313..25591)
                     /locus_tag="VUZ44_000976"
     CDS             complement(25313..25591)
                     /locus_tag="VUZ44_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319914.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(25805..27436)
                     /gene="rlmD"
                     /locus_tag="VUZ44_000977"
     CDS             complement(25805..27436)
                     /gene="rlmD"
                     /locus_tag="VUZ44_000977"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU0319915.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLIRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSQKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(27510..28484)
                     /locus_tag="VUZ44_000978"
     CDS             complement(27510..28484)
                     /locus_tag="VUZ44_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU0319916.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTSDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(28558..29172)
                     /gene="pmp23"
                     /locus_tag="VUZ44_000979"
     CDS             complement(28558..29172)
                     /gene="pmp23"
                     /locus_tag="VUZ44_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU0319917.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(29172..30146)
                     /locus_tag="VUZ44_000980"
     CDS             complement(29172..30146)
                     /locus_tag="VUZ44_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU0319918.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(30154..31410)
                     /locus_tag="VUZ44_000981"
     CDS             complement(30154..31410)
                     /locus_tag="VUZ44_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU0319919.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(31472..31903)
                     /locus_tag="VUZ44_000982"
     CDS             complement(31472..31903)
                     /locus_tag="VUZ44_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0319920.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAVNHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(31905..32507)
                     /locus_tag="VUZ44_000983"
     CDS             complement(31905..32507)
                     /locus_tag="VUZ44_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU0319921.1"
                     /translation="MMDRIRQELEKGGAVILPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEV"
     gene            complement(32491..33330)
                     /gene="prmC"
                     /locus_tag="VUZ44_000984"
     CDS             complement(32491..33330)
                     /gene="prmC"
                     /locus_tag="VUZ44_000984"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU0319922.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(33330..34409)
                     /gene="prfA"
                     /locus_tag="VUZ44_000985"
     CDS             complement(33330..34409)
                     /gene="prfA"
                     /locus_tag="VUZ44_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU0319923.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(34419..34898)
                     /locus_tag="VUZ44_000986"
     CDS             complement(34419..34898)
                     /locus_tag="VUZ44_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0319924.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(34888..35487)
                     /locus_tag="VUZ44_000987"
     CDS             complement(34888..35487)
                     /locus_tag="VUZ44_000987"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU0319925.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            35610..35792
                     /locus_tag="VUZ44_000988"
     CDS             35610..35792
                     /locus_tag="VUZ44_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU0319926.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            35928..37301
                     /gene="mnmE"
                     /locus_tag="VUZ44_000989"
     CDS             35928..37301
                     /gene="mnmE"
                     /locus_tag="VUZ44_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU0319927.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(37348..38283)
                     /gene="dapA"
                     /locus_tag="VUZ44_000990"
     CDS             complement(37348..38283)
                     /gene="dapA"
                     /locus_tag="VUZ44_000990"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU0319928.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     IPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(38339..39415)
                     /locus_tag="VUZ44_000991"
     CDS             complement(38339..39415)
                     /locus_tag="VUZ44_000991"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU0319929.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKT
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGAVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGAKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(39757..39829)
                     /locus_tag="VUZ44_000992"
     tRNA            complement(39757..39829)
                     /locus_tag="VUZ44_000992"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39794..39796),aa:Thr,seq:ggt)
     gene            complement(39929..40438)
                     /locus_tag="VUZ44_000993"
     CDS             complement(39929..40438)
                     /locus_tag="VUZ44_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU0319930.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(40436..40532)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            40561..40992
                     /locus_tag="VUZ44_000994"
     CDS             40561..40992
                     /locus_tag="VUZ44_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU0319931.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            41074..41451
                     /gene="mscL"
                     /locus_tag="VUZ44_000995"
     CDS             41074..41451
                     /gene="mscL"
                     /locus_tag="VUZ44_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU0319932.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(41493..42587)
                     /gene="hemH"
                     /locus_tag="VUZ44_000996"
     CDS             complement(41493..42587)
                     /gene="hemH"
                     /locus_tag="VUZ44_000996"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU0319933.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESQDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            42742..43965
                     /gene="pepT"
                     /locus_tag="VUZ44_000997"
     CDS             42742..43965
                     /gene="pepT"
                     /locus_tag="VUZ44_000997"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU0319934.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(44001..44630)
                     /locus_tag="VUZ44_000998"
     CDS             complement(44001..44630)
                     /locus_tag="VUZ44_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319935.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLEPTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            44595..44816
                     /locus_tag="VUZ44_000999"
     CDS             44595..44816
                     /locus_tag="VUZ44_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319936.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(44953..45162)
                     /locus_tag="VUZ44_001000"
                     /pseudo
     CDS             complement(44953..45162)
                     /locus_tag="VUZ44_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(45283..45425)
                     /locus_tag="VUZ44_001001"
                     /pseudo
     CDS             complement(45283..45425)
                     /locus_tag="VUZ44_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(45459..45599)
                     /locus_tag="VUZ44_001002"
     CDS             complement(45459..45599)
                     /locus_tag="VUZ44_001002"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU0319937.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(45643..46203)
                     /locus_tag="VUZ44_001003"
                     /pseudo
     CDS             complement(45643..46203)
                     /locus_tag="VUZ44_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(46429..49548)
                     /gene="phtE"
                     /locus_tag="VUZ44_001004"
     CDS             complement(46429..49548)
                     /gene="phtE"
                     /locus_tag="VUZ44_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU0319938.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDLNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNSSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSIGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(49770..>50198)
                     /locus_tag="VUZ44_001005"
     CDS             complement(49770..>50198)
                     /locus_tag="VUZ44_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU0319939.1"
                     /translation="DHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT        14380 a        10003 c         8050 g        17765 t
ORIGIN      
        1 tcagctaatt ctcgctgaga catttttaat tcttttcgtc tattttttaa tcttgttgct
       61 aatagtgtac ccacgtttgc atcttccttt tctatttgat ttcaatgtta attgtaacat
      121 gattaaatct aaatttcaaa tatattttac aaaagataca cattgtatat aattattggc
      181 tagattccta tttttgaaaa tctatcccat ctccttttga aagtcctgta tttaagcgat
      241 ttataaattt atctagcctg actaccatct tttcatacct gcccctttcc aattccagtt
      301 gattccccag gctcttcaat tttttctcaa caatattagc actgatattc tcagttatat
      361 tcagttttga aagatttaat ttcatttctt gcttactttc aactgaagcc agtagatatt
      421 ctgctacttg attcaaggtt gacattcgtt cttgcaactc attgattctc aattcagacg
      481 ctgctagttc atgcactaac tcatctttaa tcgtgacata agattgattt tctacttcca
      541 gttcaatcaa agcatccact tccgcaatct tctctttaat catatcgact gtcgcttttc
      601 tgcgtaatgg aatggtttga ttttcatagc tgaactgtct aattaaggtt cgacctttca
      661 tataacaatt tttctcggca gcgtctttgt ggtagacata gtaggagctg gtttccctga
      721 tgaaaacctt caccttatcc tcttccatat caagctgcat gttcggcaca aagataagtc
      781 cctcctgacg aataccaaac ttgaccttga cgtaaattcc atcatccact actttttcaa
      841 tttgattgag tgacaactcc acctcaaatt catgaacggc atctctgtta ctcttgaact
      901 cttgatagga ctcccagaac ttctcatcgc ttggaagttc tttttctttg gataactttt
      961 cttcttgata aagttgaacg aaatcctcag tttctggagc ttgccaatct tttctatttt
     1021 taaaataatc ttggaaaaac tctacatcat aaagattttt ctggtctagc tctgtctcct
     1081 ttacctccac tcctgcaaat tgaaaagaaa catgcttttg tttaggattg atagttagtc
     1141 caaaaagttt tgctttctga agtaaatcat ccatattctc aactttcagc aataaaaatt
     1201 ccatgagact ttctatttct cttttggcaa agtagttctt aaaaaattct tctgtgtaag
     1261 gctgcttgcg attgagttgc ttgccacgca ccacctgttt catagttgag tccgtaataa
     1321 aaaaggtggc atgcttgtga cggaaatcca tctccacatg tagtagcgga gcattctttt
     1381 tgaaatcctc aaagtcccta gaatgttcca tcaaaaaata gagtcgctgc ttgagttcat
     1441 acttgtgatt agtcttacga tagacttcat accgctggtg agaatagcgg ttctcaatga
     1501 ttttagcacc tgcgatttta gaaaaacggt cagaaatcac gcgaagattt cgctccacct
     1561 tgtagtccca cttgagcttt ttgtcagaat tgctatctac tgaattgata atgatgtgat
     1621 tgtgcaggtg gtctttatca acatgggtcg caacgataaa acgaaatttg ccaccagtta
     1681 attccttcac agtctcataa cctatccgat tgatttgttc aggagtgaga tgatcctctg
     1741 gtgagaaaga ctgaatgatg tggtgagcgt gtatttttcg ttgattttct tccatcctgt
     1801 cgtggcgaaa atcgtaaagc gtatcgttgc tgatgaaatt ttcatgatac atctgcacca
     1861 tttcctcata gctaggaaag tccagaaaat tcttcatgcc atagtccgac accaaggcaa
     1921 gattattggt tttctcagga ttgagaatgt acttgataag ctttctgcgg taactctttc
     1981 cgtgaatggc aaagtgttta gtgatgacca tggaactcct ttagcttctg cgcttgcaga
     2041 ttaaattcct tatcaacttc ttttatcaat tcaccaattc cttttttcaa ctcctgcaat
     2101 tcttcaccag aaattaactg agattgatta acacttcgag caatctggtt gatattattg
     2161 ccaatcctct ttaactcaaa cactaaatct tggtaaccgt ttgtgtcaat cgtgataaaa
     2221 ttcataccag gatcgagtag agttcgtctc gcatattcag aaaaggattt acaaccactt
     2281 tgatcgatat ttatatttag ttggttcaac tcactatcag acaaaaacac tttcttgaga
     2341 ttggttcggt aacgatgttc catgtgctta cctcatgtac ttctcacgaa attctttact
     2401 gaggggtatg gtgtttgcaa cctcttgaat caattcctgc acgcacgtta agagaataga
     2461 tacatgctct tgggtgactt gacgttctga ctgtgccaag attaaaactt catgaacgtc
     2521 acgactgatt tgttctagtt tttgggattg ccagagggca aaccatgtct ccatctgttt
     2581 ttgtaaatca gaggaaagta aacttttacg aagaaaatca gagaaattag tctctccccg
     2641 ctctctcatc aaagctagaa tttgcttttc ttctgcttct gttaaacgaa attgtttccg
     2701 aatatcacgc acatctcgtt tcatactgct acttcctttc caaaatactt gtactgacaa
     2761 tgtgagctac catacaatgt cagtacactt ttccaacaac tgattttcat tcttgtaagg
     2821 ctttgcgagc tcagatattg tgtccacaat atcccaaaaa tcatatcgcc agcctatcaa
     2881 aacctaccag ttttgacagc taacgataag ataacttagt ggctccgccc ccaaaccccc
     2941 aggtaaaatt cttagttgga tttttaaaag ttgagaaaag tatagcagaa gaaatttggg
     3001 gaagttatca caaatcaagt aaggactaat ctctaacacc actgcatgta ccgtcctata
     3061 tttatgatca gctcccatcg tttacatttt caggtcactg tcttttcata ccaggaatta
     3121 gaattgacaa atttaattag agaggtattc atttaattgt tcacttcttc gctccatttc
     3181 cattacagaa atttcttcaa tactatgtgt tcagctgact cccatgattc gttgtactac
     3241 gtcctaaacg ctcacggaat aagccgtaca tctttcctag tttactctcg taatttacgt
     3301 atataggtta cgacacctat ttggatttta gagttcctca tccgctatat atggcttcaa
     3361 gtcacgattc tgtttgtaga accttgattt cgctaattcc ttcctatccc ccctacctca
     3421 cgatattcag gcttaggagt cgctattggt ttcatctgca gcaaatatcc acagaggact
     3481 tggacctcag atgtacacta tgcctgtcgg acaaagaaaa aagtaggcta aatttctaac
     3541 ctactttttc tgactctact ctgataaagc cgtctcatat atagacattt tatgcttgaa
     3601 ggaatctttt cctccctcta attgattgat gatatgattt tttatatatt tttcactaac
     3661 atatccctgt gattcaatcc atccgttaac tccatctgac tccataataa caacttgatc
     3721 tgtcatagaa tttgttacaa ttgtagtatt atgtgttgct aaaataattt gacgttgagc
     3781 tttcacatct ctaaactgct gaactaaatg cctgtaaata taacgattgt ctagattgtc
     3841 ttcaggctga tcaataatca atggtctgaa gtctttagaa taatcactat atgctaataa
     3901 aaaatcaagc atggctacaa ctttttgtcc caaacttaat acaccaactt ctttatagag
     3961 aatatcaagt tgttgcgaag attctttcga gttaatatta aactccaaaa atcgtgtatt
     4021 ttctttagaa aaaatttttc gtttatatgc acctaataag tgagaacctt ttttcaaaat
     4081 gtcataacta ttgaaatgag caatatagtt aactattttt tgattattga aatccttcat
     4141 tatagtcagt gaatgttgat aacttccatc tttctcactt ataatatttt cacttaacca
     4201 ttgattaacc catgattctt gttcataatc atatatacat acaatatgca atttatctgc
     4261 tgcactaatt tctactccat gtaaaatatg aggatgtata tcataaatcg gataattttt
     4321 cattatgatt gagactgcca tttgtaactt tttaatacct ttggtagtat tatgatcagt
     4381 tactacaact atttctattc cattttttat gattgcctct gctaacataa gaaaactaat
     4441 atattctttt gaactagaaa aaacaacctt atcaaaatta ctaaaaaaaa ttgtcttatc
     4501 aacttttatt ttcttatttt caaaaaatat atcatatagt tcatcttcag taatttttct
     4561 atatttcgtt gcagtccaat tagaaaatag cttgtaatca taagaaacag gtgtatgcaa
     4621 atgaattaaa gtcttgtgaa agctaccgaa tttctctttg gaatttgtta gttcttgata
     4681 aacagacttt atcttgttat taaaccctct catttctatt ctcctaaaaa tatcaattgt
     4741 ttatttttca agtaattcat taagtctctt ttcccccacc tgcaacatct ccttctctac
     4801 ctgactccac tccccaaaga gtaactcttg aagaacatct gctgctgaag ttgtattttc
     4861 ttttgaatca tatacacaac ttctatctcg ttggtaaatt tgaattcttt caaagatagc
     4921 tagttcttcc aattttcgtg tgttatcaac tagatgattt acaatgaaat catgatgttc
     4981 ttttggagtt gcgcgtgctt gatttggatt gataatgtac agttcttcat aacggataag
     5041 agtacttaga tacgacaatt caggctttgt cgcaattaag gccaattgta cttcatatcc
     5101 cttatttttc aagagttgtg ctgttttctt tggaacatca actgttcgta aagttccctc
     5161 tatcaaaaga ttgtatctca aactactcaa ttttgttact aaagactcta ccatttttcc
     5221 tgcaaaatct ttggtatatt ctacactgtc tttgccatat tcttgctgca gttctaaata
     5281 gtgtggatgc tgagaacgaa aactatcacc atctatgata acaatatttc cttgaaattc
     5341 tttctgttta atacgatgaa ttgtagtctt accggcacca ctttgccctc caagcaaaat
     5401 cgctataggt tgcttactgg acttttttcc tcttgtcagt gaacgaagat tccttgctaa
     5461 agcatgtttg aattcactat cagtataatc ttggatttcc attaagctac catccgcttt
     5521 tcagatatct ctaacatacg ttcaattcca tccaaatagc cactatatct ctctatttca
     5581 tcaaaagttt ctactaaata gatattcgta tgaatcaagt cagatagatc atcactcatt
     5641 aaaatccaag gattagattc atcatcaatg ctaattccct gactatcttg ataacgatag
     5701 agtcgagata atagattagc acctctttct ttcacaattt caattttcaa agtcaattca
     5761 taatcttcaa caggattgag cattttatct tctcctacaa tatcgacata agatacatta
     5821 aacttctgac aaatgatgtc aattaattcc gtagagactg aactagttcc attttcataa
     5881 cgactcaagc tatttcgaga aattcctata attcgtgcaa attcgggttg tgttaagtca
     5941 tgtgttttac gtaaggattt tatgttcttt ccaatcatag caaactcctt tatttttata
     6001 aatccattat agcataaaaa agcataacgc accaaaaatg gtgcgttatt tcttgttttt
     6061 ctatcctaaa ctttacttct ataaaagtca cctaaagagc tataaatatt tattcttgta
     6121 ttaatttttt cgatgcgcaa acgatatcta caaatacatc tataacgatt caccttttag
     6181 gatttttatt gtcaaaattg cctttatcta caaagacaaa atgcttataa aatagcttga
     6241 aatcaaggat tatcaccttt ttcgttgtag caacactcca catgtgatta ttaggctatt
     6301 agcaaagcgt atccaatacc tcaataaagt gttgttttta ctgatatttt aactatattg
     6361 tatagtctac tatttaaatc tcaattagga tattttatag aatacccaaa attcaacaat
     6421 aactaaaagt aagattccat tgtatttcct tgttggtctt tcatatcacg aattttattt
     6481 ttcagaatat taaagttaca aatttcatct ctaatatcgt tatccgctct gtagccatta
     6541 atcatctcag tcagagtttt ccctttacta ccattcttta tagtagtatt tactcttttt
     6601 atactgcttt caaaaggctc atatgtttta tacttaatta cttcgtcttt aaaattaaat
     6661 aaaggtgtat ccggcttagc attccataaa ataatcaacc acattataac attataaagc
     6721 tgctttgcag tttcattcca cttttcaggt tgtaaatttc cactccctgt attgtcatat
     6781 tcttgtctat tatttacatg agaatcacct acaagcggat taaaaagagg tagccctttg
     6841 tgattaatta gttctaaaaa atcccttgcc gcacccatgc aacactgaat aacttccttc
     6901 ttgccatcaa ttttactctc agcgataaat acataatatt catcttcaat agttgctcct
     6961 gcatcactat gtttttgttg atttgctaac agcttaatat gtgctttagg ctaaacttca
     7021 aaatctctaa caattctttg tcttgtttca tgtcctctac aattcattta agttctcctt
     7081 tacaagttta gtaactagcc ttattatact atataagata tgaaatgtac cataatcttc
     7141 atcaactagt ttttagaaaa tcacaaatcc atctggagag atgacaagct gattctccaa
     7201 ttcttggcaa ttgcttgcta gtgctactgc ttatttctct aaaagataat cttctgttga
     7261 ttggttgaat attgctttga ggatccgtcc ttcgtatttc cattccagag ctactagatc
     7321 agatttgatt tcttgaaggc tatacttgcc atgcgaaatg attactgacg cgtatttccg
     7381 aatcttaatc agcctcttca taaagttcag catatcattg tcacttgata cacgttccca
     7441 aggcatacaa cgacgacaat ctggatctgg tcctccagtc aaggctagct cggttccgta
     7501 ataaatgcac ggtgttcctt tttgtaaaaa gagaaaggct aaggctgatt taaccagttg
     7561 aacatcttca ttggccgtcc acaggattcg ctctgtatca tgtgaatcca agagattaaa
     7621 catgacctct gaaatctgct gcttgtaata catagactct ccattgattt catcgatgaa
     7681 ctggtctgtc ttcttaattc ctcgtaagaa atagtccttg atactatcag ataaaggata
     7741 attcatgacg gcatggaact catctccatt tagccaaggc tgagatgtat gccagacttc
     7801 tcctaggata taaagatcag gatttttagc taaaactgcc ttacgaaaat ccttccagaa
     7861 ctgatggtca atctcattag ccacatccaa acgccaagca tcgatattaa actcttcaat
     7921 ccaataagtc gcaaccttta aaagataatt cttgacctct ggattggctg tatttagctt
     7981 aggcatataa tcctcgaaac caaaaacatg atagggtaag tctctcttat taactagctt
     8041 ttcagttgtc actgggaatt gttgaatatg gaaccaatcc ttataagcag actgttcacc
     8101 atttttgacg acattttttc attgaagaga ttgcgaacca atataattaa ataccgcatc
     8161 cagcatgact ttcatgccac gatgatgcgc ttgatccacc agttcccgaa aggtctcctt
     8221 gtctccaaaa tgacggtcaa tttcaaagta atctgtcgta ttgtacttgt gattgcttgc
     8281 agattcaaag atgggacaaa gatatagtcc agtaataccc aagtcttgca agtaatccat
     8341 atgatcaata atcccctgta aatcaccacc aaagaaatca tcgctcttag gtgtgacaga
     8401 tgaatcccag tctaaagtcc cttctgggtt taatagagca ttgccattgg caaatctttc
     8461 aggaaatatc tgataccata ccgtatttga aacccagtca ggaaccttgc aggcatcaat
     8521 ctcatgaaga taaggcaact taaatccatt cccaattgca tgaagatttt ctagagaatt
     8581 ttccacacac cctttatcgc catacaaaat attttgacct tctgtatctc tgagctcaaa
     8641 gagatactgg atacgtgcaa agtcaactga cacttcaacc tgccaatggt caaataaggt
     8701 accagaagtt atcttgacca tttcttttgt atcctgataa aactcctcca taaagataaa
     8761 agggtcccca tagtgcaagt ttatgctttc aatgtcccct ttcttagttc gaattcgaat
     8821 atggagtttc ttatccttat aaagataggc atactccgac tcaggcctat ggtaaatagc
     8881 actcaattcc atcaatttgt ctcctaaagt attcattcaa attttacgca aacgttttca
     8941 aactcaatga atccagtata ctatttttgt aaactatttg caaggaatgt ccgttgttaa
     9001 aggaactatc ttttaaagta tacaaaaagc cttaaaaaag gctttctcta tatactaatc
     9061 ctctttcggt tttgaaaata cttctactcg ctgagctagg actttgattt ctacaggtag
     9121 gttatctgat ttatctccgt caacatctga ctccaattca ctatctgaag agattttaat
     9181 attacgcgct ttgatatact cgatattatc atttgcgaca acatcccctt ttaataaatc
     9241 aggaatgacg gataatttgg agaatataga ggcatctttc agaatcaaaa tgttggcata
     9301 gtcgtccttg ttttcttcaa agattttctt atcagcgaag taatttgtca aaaggaccaa
     9361 aacatggcta gcttcaccaa cataatttcc attttctgtc tcaaccttaa tgttaaagac
     9421 ctgatctgtc atgacagact tcatggtatt tacagcatag gttaaaatac cgaattttgt
     9481 tttgtcctct atttcaacat tgtgaatcgc ctcaggcaga gaaccgatac taaagatata
     9541 accaaaatag ttgtcatttg ctttaccgat atcaatctta ttggttaaat caaaatccag
     9601 ttcgtcaatt gcgccatcga tgtcttgatt gatttccaaa agttttgtaa tgaggttacc
     9661 cgtaccgcct gggataatcc ctaacttagg aatgtagtct ctctcatcaa tacctgaaat
     9721 gacttcattg acagttccat ctccaccaaa cacaaccact gcatcatact gctcacgaga
     9781 agcttcttca gcaaaatgtg ttgcatccag cgctttttcg gtaattttgg tttcaacata
     9841 ttcaaagtat tcttttgctt tattctccag cttttctttg taatccaaag ccttctcgcc
     9901 accagaagta gggttgataa ttaccattgc ttttttcatt gattttatcc ttaattttaa
     9961 acagaaatgt ttacatttcg tcgtatgcaa gtaaatgtaa tcctattata caatgaaaat
    10021 acagaaaaga gaaatctgac gtactggaga ttaatacgct tttattctat tttcccatcg
    10081 cctaactaca tcctttaagg gttcatccaa gtaagaatag gccttatcct tgatccaatc
    10141 aggaataccg taagctgcct ctgctatgct acaagtgatt gctgcgagag tatcactgtc
    10201 gccaccaagt gagatggcat ttcttatcgc atcttcgaag tctctacttt caagaaaggc
    10261 gataatggct tgagggacag tttcctgaca tgtttcgtta aaacgatagt taggacggat
    10321 ttcatctaaa gtttgagata gattgtaatc gtattctttt tctatataat ccttaattcg
    10381 tcttttacac tctgtaggat tgtcgttaat tgattgctcg tactctctac aataaccacc
    10441 aaagtaaaaa cgacatagaa agatagcatc agctgtagcc atagcgcctt tgacaccttc
    10501 tggatgatta tgagttacct ctgcagaaag actcgtaagt cctctagatg atggccacat
    10561 accagttttc gcataaaaac cacagtccat gatccaagca catggagaaa tacgcatagc
    10621 tgatccattc ccaaagctat tataaggctc acggttatcg ctgtttagcc atgcattaaa
    10681 ccgagcaccg taatcagcat tcggatacat tctgccatat ttcttcatcg cgtcaatgaa
    10741 atcgtctttt tgtccaccat tcataattgc ttctgcaaca gcacaggtca taaccgtgtc
    10801 atctgtaaaa aagcagtcct tccgaaataa aggaaagtcc tttgttttga tattgttcca
    10861 ttcgtaaaca gaaccgacaa tatctccaat aattgctcca agcatcagat tcctccttgt
    10921 tcattttgat gctttttata ttggttatct accatattta ttttagaaaa taacatcctg
    10981 ttggatttta aaaatttcat ttttttcaaa atagggtttt accatttctt tccacctagc
    11041 tctatgaaaa ttgattgatt ttaaaggaga taggccataa tttcccaatg cataaccatc
    11101 atttacttca acaacaagtg ttctgccatc gcgagtaaca ccgatatcta gtccataagc
    11161 tattggcgca tctttccaac atgatatcgc ttcatcaatt acacttgcat caaattgtgc
    11221 atgataatca cctgtatagg gtcgaacatc taatacgcga ccatctaaca caaaacaacg
    11281 ccattcagct atgaattcta caacctcact aatccatata ggatagtcga aaggtagacc
    11341 aatacctatt aaatcatagg ttccattaac aactcttcca gtaaagactt ttgaaccagc
    11401 tttaggctta ataaattttc cccaattatc aggtatattc acaatctctc ctaaaatacc
    11461 agcataaatc tttcgaccat aaaactcttt aagctcaata ggatagtcat gaaccggaac
    11521 gtttaagccc atcattttta gtaatgctct agtctccatt atataatcta caactatatc
    11581 ttcacttgtt aactctttta tttcagaaaa agattgatat aaaacagctt cttctccttg
    11641 taagtaggca cctacttgag cattgtattt attaattgaa acctcacttg gtaatttact
    11701 ttgtctaata taaacaacca tttcatcact cctatatcac tagtgttaca ccaatttgta
    11761 aaaaataata gcaattttgc tcttattttt ttgagtaaat agcccccata atatcatcga
    11821 aataatcaac ggtatttagg agtaattcaa taacctggga ctttgttagt cgcattcccc
    11881 ttctatctct agcatcttct actaaatttt caagtttctc tagattttta tcatccaagc
    11941 taatcattat tctattttta tcggttgcca ttttcatcac ctcaagttaa ttctatcaca
    12001 ggtgtaacac ttgtgtcaac tggcttttat aatacattag tttaaaagtg gagaggattt
    12061 ttaacacagt aactttaaat ctttggtatt aaaaaatttt cacaatattt atagaaataa
    12121 aatctgtctc aaatcagtta tcaaatctag tataaattat gagcggctac tctaatactt
    12181 tccctctaaa caagaaaaag acttacactc aagggttttc ttccccccct tcgttataac
    12241 gttttgactc ttttactagc aaaggtatat actcacaagg aactttggtt gactattgaa
    12301 tctctccaac ttcttcttta acatatcctt ctacatcttc aatctctaca aacattgggt
    12361 ctaagtgaca caagaaatgc caaacttcga tccctttttt tctgtaaaga atcgcttcac
    12421 cgtcttcact tccgaaaaag cttctgtcga tttcatatcc gcggctttct aagaagtctt
    12481 ttgctttacg atagttcgtt tctcttgttt cgacataggc tttaacttca tggttgttaa
    12541 cgacatatgc atcaattttt gaatatcctt cgatcactct atcatttttg agggataaat
    12601 ttgaaatctc tttccaaata atgtttacat tttcctcagg atcgaacata aatttagata
    12661 aaggaacaat atttccgtta aaaataattt ccatataatc cggtatgttt ttaggattaa
    12721 aatactccac ttcaaaacca tcttctgttt ccagagtgta tcccgggatt tgagccacaa
    12781 aggctttccc atcttctatg gaatcaaatg ctactaaatc tttagaataa tcattttggt
    12841 acaattccaa tataaccatc gataatctct ccattttcat tatcaggcta atgtaaataa
    12901 gcacgtcacc tgaccaattc aggctctctg tatcatctca tcatatttcc tacttacttt
    12961 acgagtccta tacccagaac acaccttatc gaccttcggt ctcacctcgt cgcattggct
    13021 gaacatctac ttttacttcg ctgatgcttc aactcgtaca agcagtgata ccgcctcagc
    13081 gtgatgcgtc agtgggactc aaaaagtttg gggaaccttt tgaggattaa ctacgtttct
    13141 ctaataaact tacacattca acttgttcat cattgtccaa atctatgttg agattttctt
    13201 ctataattgg tagcttaaaa gtaatggatt ttagccattg tccgttagat tgtttttctt
    13261 cataaacttg aatttcagaa atcaaagctg aaattaactg cctacgctct acatcattca
    13321 tgactttata gagcttatca aaatagatca gaaccttata tatgttatct cctgtaagct
    13381 tttcagcttc aatagtctgt ttctttgctt tcgcatcaat tagtgatgat tctaattcat
    13441 ctattttgtc atacatacga tatagtctat catctaaatc ctgtttcctt ctcttataat
    13501 gcttatcttc aacatctaaa ttatctattt cctcaattag cttaaacttt gtagaatgac
    13561 tctttctcaa ttccttttgg taattatcta tttctttttc tatttcagag gtatccacct
    13621 tcatgttgat tttttcttgc atcatagaag caaatttcgg attacttact atcttgacaa
    13681 tcacctctgc aacagcatca tctaacaatt cttctctaat ttgcttactg aatgtacact
    13741 tatgacctct tatcatctgc ctatgtttat aaccatagta ataaaaatct ttatactttg
    13801 tgccatcttt ctttttcttg atacacttgt tcccaaacat tcccactcca catatcgggc
    13861 attttacaat tccagaaagc aagtgtgtgc gtgtatcttt tcctttattc acatgctcat
    13921 atttctttgc ttgagatttt agcttaacct gagcagcttg ccaaacttca tcggaaacta
    13981 tagcttcatg tatcccttca gatattagat attcatcttg ttcaacctgc ttatattcat
    14041 ttcttgtacc atgaactttt tctaaagttc ttcttccaaa tgctattttc ccattatata
    14101 caggattctt taatatcttt cttataagac ctgcatcaaa caaaggattc ttaccattct
    14161 gtcttgggat ttttctaatt ccatgattct ctaagtattt agatatccca ttggctccta
    14221 tcgtagtatt tacatactgg tcgaaaatcg ttcttattgc aactgcctct tcctcattta
    14281 taaacagctt gccgtcttca agtttatatc catacggagc aaagccacca ttccattttc
    14341 cttcccttgc tttttgaatg cgaccttcca ttgtttgaat acggatgttt tctctttcta
    14401 tttcagccac agctgataaa acagaaatca ttagtttccc agcatcttta gatgaatcaa
    14461 tgccatcttc aacgcagata agattaactc cataatcctg cattatctga agtgtagaaa
    14521 gaacatcagc ggcatttctt gcaaatcttg ataacttaaa cacaagaaca aaagatactc
    14581 catcttttcc agattttata tcttccatca ttcgattgaa ctgtattcta ccttcaatag
    14641 acttgccaga cttcccggca tcttcatatt ctccaacaat ttcataatca ttgtaaatag
    14701 caaaagcttt cattcgtgat ttttgtgcct ctaacgaata cccctctatc tgtattgacg
    14761 tagatactcg tgtatagaga tatactttta ttttttcttt tgacatagta ttaacctcaa
    14821 tataattttt ctatatcata tataattttt ttaatttaag tttggactat catttcaagt
    14881 atattataac acttttatta gtccgtctca atttgtgttt ttgccatgtc aaaactattt
    14941 ttcatctctt gattttttgc tggcgttgga tcgggtagat tatctaaatc taaagcacca
    15001 gcatattttg caatcagatt tgctattaaa tcagccaatc cattccagtc attgtccaat
    15061 atatacctcc tctaaagttt tatatctaat aattatttgt ttaattaagt tttttgacat
    15121 tgacaagtgc tttggattag caacatagga atctcacctc cgcctctatt ccggatgagc
    15181 cggcttcaac cttagaagta tcattatcct cattttcttc atagcggata gggtatccct
    15241 ccctatattc aaactcttac ttatcgctca ctttcttttt gcttagcaga actttttttg
    15301 ccgaattatt cagccgaaag atcttgacgg ataggttatt acgctccaaa aataattaac
    15361 gtcttgtctt ggtctattca attgttaagg ttcaaaattt atcgagagtt attaatcttt
    15421 ttaaaatttg accatcagaa aatatttatc ttgatgtaac aaaattctat aaattaccct
    15481 cttatactta acagtgaaaa gaagtctttc ttggtaactg tcatctaaaa gtcttctagc
    15541 atttctttaa ttttctaatc gcctttaaag tgtcatattt atattttttt atctctggca
    15601 tactttgata cctttttaga cttaaagtct ttaatagtgc ctttccacct ctttttatct
    15661 ataaagattc tcctacatca taattcattt ttttatttaa acctttctgt cttagtttgt
    15721 ctttatcttc ttcataccat tttaagattg tcacatagtg gttttgatag gtcttaccac
    15781 tgctttccat gtatctggat agtttattta tcattatatc tgtgtgtgag tttaattttt
    15841 cttttagatt tttatattct tctttgctta accttacatt tttgaattct ccataaaaaa
    15901 tgggggtgga ctttttatct atctctccct ctctctcttt atctatctct atctctttat
    15961 ctatctctat ctctatctct tgtcggacat gggttggact cattaaggac aatgtcctct
    16021 gtttattttg tctgtatctt ctttttttct ctgcccaggc tgtttctgat ccgattaagt
    16081 ttggtatttc agttaggtag tattcatcat tttctgttac aacttctaat aagccttgat
    16141 tgattaaata atttactgtt accattacat catcgtctgt ttcatctatg gttagtgcta
    16201 actcttttat aaaatcactt tctactccgt cataatagag tttgccctca tcttttaggc
    16261 ttagtagtag aagttttagg tagattatcg tataggtatc tcctccagat attctcctta
    16321 acctttttat ccttttgtct gtgaaaaatt cttcttttaa ttttatccaa tagtatcttt
    16381 tgtttgttgc catatctgct cctttcttga ttttcgataa tcgaaattct tgatttccga
    16441 ttttcggaat tctggacttc tgtttttcgg aagtcttgtt attatggtta tttaagggtg
    16501 taacttttcg ttactccctt tagatttctc tggtcatatc ttttttgttt ggttttactt
    16561 tttcttttac tttccttttt cctttttctt ttgtcttatc tttgtttttg gataggtctt
    16621 tgtatttctt tatttgtttt aggatacttt ctttttcttt tttattttcc ttggctatga
    16681 cttgcttaaa ggcatattcc attactttta tgtctttggc ttggaagaat atttcatagt
    16741 ttttgctttc tttgtttttc attactgaga aacttactcc aagtttgttt agttcttttt
    16801 ttaagtcttt gaggtcgatt tgatctatgc ttatattttc tagttgtcct ttcttgtaga
    16861 gatcttttat tttcatttca tcgcccataa gactttttaa gtttccattt gctttttcta
    16921 aagtttcatt catctttttt cttatttctt tttctaaatt gattgattct tttgttgcct
    16981 ttattgtgta tgatattatg gtttgtgctg cttgacctgc ttccttgctt atttcttcgt
    17041 ttatcatgct tttctctcct ttgtttgaat taaaaaaggg aagtataggt tttaattttt
    17101 ctatacttcc ctttgcttgt ttttatttta ttgttcttgg tggtggaata ctttattttg
    17161 atgtttttat atatttctta ggtctttgta ccttttatac ttttaaaaat agcttacact
    17221 acctttccac ctttaatagt ttatgtgtgt tcttttgtct gatagatagt ttttcatgtt
    17281 ggaatatata atctgtattt cttcattgtt cattgctttt atttcttctg tgcttttata
    17341 ggttttgtat gttccatctt catttgcttt tatgagttca tctattagct cttgcctttt
    17401 attcatctct attacctcct agatctgact ttagttgttt ggtcatatta tagcttggat
    17461 aagatatttt taccaggtct tatctttctt gatccatttt cttgtttttc atcatttctc
    17521 tgtattcatt atctttattg acttggtctt ggaacttttt aatctgtgct attacacttg
    17581 gtttttctcc ctgttttatt agcttatcta tttctatgga taaatctata ccaagttctt
    17641 tgtttacaaa atctactgaa tattttatat gattaatttc ctggtattca tcttttatct
    17701 tgtctttttc tttatttatt tcttcaagat tttacattaa aagaattttt tcttcattcc
    17761 actttttagg acttagtttt tccttatctg ataggagttt ttttaatttc ccacttacta
    17821 ctttatattg gtctatatct ttcttatgtt tgttataaaa tgcttctttt gtgaatatat
    17881 ttttcttttg atattcttca taaacttctt ttttggcttt gtagatttca tagtatagaa
    17941 ttttcttttc tacatcttcc atttctttat ggattgtctt tgctttttta tttagcctat
    18001 aactattaga ctttaaagtt tctatttttg tttgtaactg acctatggtt tctatgttgt
    18061 tttttcttaa ataactatat gcacttgtta gctttttgaa gtcatatttt tctttattag
    18121 tttttgcata tccttttaga tatttacttt tttctttttg aatttctgaa taagttaata
    18181 gataatttgt tagattaaaa agtttagggt tgtctattac cttatctctt tcgatatcct
    18241 taaatttttc ataagcagta gataagttat ctaataaatt tcctatccaa ccctttaatg
    18301 tttttatctc ttcttttatt gtttttacaa gttgattata ttttcttatt tctctattat
    18361 agtttccctt gtcagtttct attccctttc tttccattgc acttgctgct gatcctaaat
    18421 ggattgtcgg tagataatct gaattttgtc ttttaaaact cctatggtct actctttttt
    18481 ctgctcctgc tctttctaaa tatttgttac aaagatctga aaaattttct ctccattttt
    18541 ctacattgcc tgtatcgttc caggttgtta gttctacttt tcttgtcttt ggttttccat
    18601 ttttgtttaa tacttttctc ctttttcatc taggatatat tctttttttg acttggctaa
    18661 gaactctcct ttttcgttta ttggtcgcat tatggtcatt atatgacaat ggatatttcc
    18721 atttttatct tgactctcat catgaattgc ataatctact atcattcctt gtgatgttaa
    18781 attttctttt atatatcttt caaccaggtt tttattttca cttaaagata actcttttgg
    18841 tagtcctatt atgaattgtc ttgctagttg tgcattagaa tttttttctg ccatttctac
    18901 tttattccat aaggtagacc tatcattaaa ttcttttggt atatgatcag gcaatattat
    18961 attttttact aatatttttt cttttcttgt gtagtcatgg gttactccgt cccattcatt
    19021 ttttattttt tctccactta tatatgctgc acttgctact gcacttttgc cttttcctct
    19081 tgatattatg tttactgaaa aatgaaaact gtctgccatt tttatcactt cctttctttc
    19141 tttgttgttt taggtggagg cttaatagtt tttttatatc ctctttgtga atgagcgttt
    19201 tgaaatgata aaattaaaaa agccgactac tgaattaatt tttgttgttt cagtatgtcg
    19261 gcttaattgt tactttcatt tcaaatttta aaagtcaagg gcgagcctta gcgagtttat
    19321 ttacccttga cttttaaaaa gcgaatggtt gttgctccct gcaagggttt gactccgcag
    19381 gacgcaagca ccctttaggg tgtataattg cgcccttgta accaagggac aattatgtta
    19441 tttcatcttt agatgatttt tctacattat catctattct ttcttctaaa atttccatta
    19501 tgtttaatct tatttcttca tcatttaacg tttttattaa cttataaaat tcatcttttg
    19561 ttaaatcaat actttcttca aaaatacttt cttcaaaaat actttcaaac actgcacctt
    19621 tttctataag tcttttgttt cttgcttttc tttcttgttc attaagtttt ttcttcaact
    19681 gtcttttttg attttgtaat tgcttaatgc tttcttcttt cttttcaatc tgttcttcaa
    19741 tacttaatct tttacttgcc atcatgtatc ctttcttaaa ataaaaaacg actagatttt
    19801 tatttctaat cgttcttgtt ttaaatatta taatttgcta tattgcattt taattttaag
    19861 tcttctatat atctttccat gtaattccaa tctggagtac ctctactgtc tatcggtaat
    19921 ttaattttga tatctggcaa tactgtgcta gatatttgat ctttatattc agtatttttt
    19981 aaagcttgcc taataattga agttaaatag aatgctactt ctttattcaa ttctttattt
    20041 tttaatttta aacaatgaat tttcatatct aggcttgctt tatatttatg ataaaagact
    20101 gctcctaaaa atgaaacaga tataaaattt tcaaaaactc tataattttt atcatctata
    20161 tcttcgtagt aacctaagat accattgtca atatttgtag cactaattct aggagttttt
    20221 ccatcgagta aatatctttt tggaatagat gagcctgttg gtacttgact cgatttcctc
    20281 tttttttcgg taataaatat ttctttttat tttgttgtct gatatttttc ctacctgtcc
    20341 tttgtaggat gagtattttc tagattttct tgaataactt tttacttgaa gttttagctt
    20401 ttgaactagt cgttgtactt tctttttgtt tattatcagt cctgatcttt ttaatattgc
    20461 tgttattctc tatatcctat ttttcattca tgatattctt ttactaattt tatcttaaat
    20521 tctgtgctgt atttgccatt aaaaaactga cctcctttag ttagtttttt ggcctaactt
    20581 ttgagggtca gttcaaaatt tgcgactttt aaatgaattc cgatattcaa ttattaagag
    20641 ctaacatggt gcttgccaat aggaatcatt agaggcgaat tggaaatagg gtcacgtata
    20701 atttttgctt caagattaaa gatatcttta actagtttat catttagtat atcttcaggc
    20761 tttccctctg caacaagttt accttcttta attgcaaata ggtaatcagc gtatcttgct
    20821 gttagattta tatcgtgcaa aatcatgcaa atggttgtct tatatttttg gtttagatca
    20881 gtcaagaggt ctaatagttc tatttgatat gagatatcca agtaagtagt tggctcatct
    20941 aaaagtagga tacttgtatc ttgggctagg gctagagcta tccatactct ttgcctttga
    21001 cccccagaaa gttcttcaac taggttattt gctagatctt caacattggc cttaaccatt
    21061 gatctgttta ttatttcaag gtcatctttt ccaagactct taaaaggctt tctgtagggg
    21121 aaacgaccac ggcttacaag atcagctact gttattgatt cagggattat tggagattga
    21181 ggtaatatag ctatgtgttt tgctaaatct ttttctttat aagaattaat tgatttatta
    21241 tcaagcaata cttctccctc taatggcttt ataagtcgag acaaggtttt aatgagtgtt
    21301 gatttcccac aaccatttga cccaataata actgatattt tttcttcagg tatttttata
    21361 tttatatttt ccaagattat tttttcatca taaccgcagg taagattatt tgaccacaga
    21421 cctttcatta tatattcctc ctgttcattt ttattagtaa gtatattaag tatggtgaac
    21481 ctaacaagcc agttacaaca cctactggat atctagctgg taaaatattt tgagagaata
    21541 tgtctgataa caaaactagt aaaattccaa ccaatccagc taatattggg cttcttttct
    21601 tgccaatatt taaggctatg ggaccagcta aaaaagatat acaagctatt ggtcctgtaa
    21661 ttgaagtaga aaaagcagtt aaagatacag cgcaaaaaat taaaacaagc cttgaaagct
    21721 cgggatttgc tccaagtccg attgctattt cttcaccaag ttcaataatt tctagtcttt
    21781 tattaaaaaa taaaactaat atagtagcaa taatacttac tattagaaca agaggtatgt
    21841 catctaactt tgtaaaagat aaagagccac tgagccatct cataacttct tgtaattcat
    21901 atcttgctac tttcaacaat aaaaatgagg tgcctgctct tgtgacagct tgaaaaccaa
    21961 tacctaatat tatcagtctt gctgctgaaa aaccatcttt tttagctagt aaaaataata
    22021 ttaaagatga tgttagtcca caagttattg aaataattcc agtagttaaa ctatttgttt
    22081 ttaataccaa tatgcaaaag accgctgcaa tagatgaaga acttgtgaca ccgattatat
    22141 caggacttgc aagaggattt cttaacatag tttgaaagat aaatcctgcc aatccaaaag
    22201 accagccagc tataattcct gctaataatt ttggtaatct aatttccata atcgaaaaac
    22261 tagctccagg aacagtttca ctatttaaga ctttaatcaa agttgaaaaa gaataacttt
    22321 catctccgat aagtaaaatg aaaaatgata gactgattat tattaataaa aatagtgagg
    22381 aaaatagtgt tattctattt tttctttttt gaatacctat aattaaattt tgcattagtt
    22441 attaacccct ctatttttca tagttacata aataagtact ggacccccga ttattgcagt
    22501 aattatccct acttcaattt cacctggttt acctaacata cggccgatta tatcacatat
    22561 aagcaagagc tctgcaccta taaaagatga agaaatggtc attgtgcgta tatctttgct
    22621 tataaataag ccacaaaagt gaggaactat aagacctacg aagccaatag gtccaccaat
    22681 tgcagtaata cttgaacata aaagcacact tgcaattatt gcaagtgatc ttatcctatt
    22741 aacattaact ccaagaccaa cagccatttc atcacccata gctaaagcgt ttaaatctga
    22801 tgaaataaat atagctatca agtgacctaa aattataaaa ggtagtagtg tagatataga
    22861 agataatgta gctgctccaa ggctacctat ttgccaaaat ctaaatttgt ctaagacgtt
    22921 attattcggt aaaattaaaa aacttacaaa actgcttaaa gccatactaa cacaagttcc
    22981 tgataaggca agttttatag gggtaaggcc tgcttttccg cttacagcaa tcgcgtatac
    23041 aaaaattgca cttactaagc caccaatgat tgcaaaactt atatggctta tgcttgatga
    23101 aattcctaaa aaagaaagac caattactac actaagactt gctcctgtgt ttataccgag
    23161 tatacctgga tcagctattg ggtttctagt aactgattgc atcaatacac cgcttatggc
    23221 aagactagaa cctgctaaaa ttgcaaaaat agttctaggt attcttttat atataattga
    23281 tttaataaaa tcatcatttg tattacccat tccaaaagct gctaaaaaat ctctgatatt
    23341 aatttctttt gttccaagct ttaatgacaa aaatattgta ataagaagac ctaggcagat
    23401 tacaaaaatt atgcctaggt ttatttgttt tttatttcgc atttttgcat gcatttccta
    23461 aaagatttag atattcttca atagtatagt ttattgaaag tggtgttgga gtgcatgagg
    23521 ctgctaacgg tgtattatct ggaattacag caacggcacc atttttaatt gcatttattt
    23581 tacctaaaag aggatctttt tgtaaagctt caagagtttt atcatcacca taagttatga
    23641 ttacatcagc atcatttatc ttatttgctt cttctgcaga aatttccttt gcaaaactat
    23701 cttcactctc aaattctttt aatgattcag ggaaaactag acctaaatct gttaaataat
    23761 ttgctcttgg atctttgcta gtataaatcc agaattttga tgtatctgca gcattaatca
    23821 tagtaaataa tacttttttt cctttgattt ttcctttgat ttctggatgt ttttctaatt
    23881 ctttggatat acgagcttca gtatttttga ttaactcatc accttctttt tccataccta
    23941 aggcttttga atcaatttta atcatatctc tccataaagt ttgccaaggt ttagatttgt
    24001 atgctgctac aggagcaatt tttgatagag tgtcataatc ttctttagtt ataccagaat
    24061 aacctgctaa gataacatct ggtttagaat ttgatattgc ttcaaagtta agtccatcca
    24121 aatcgtcaaa taggttagct ttaccattta gttctttgat tttttcttct gtccatggta
    24181 aaactccttt atcagcactt acaccgtaat ttgcttttga aaatccaaca ggaactattc
    24241 ctaaagctaa tgctacatca tgatttcccc aagcaatagt tgcaactctt tcaggttttt
    24301 tatctaatat agtttgaccg aaagcatgat ctaaaactat tttatcaggc gcatgctctt
    24361 tagaagtatt ttcttcattt ttaacagaat tagaagaaca agcgctaaaa actatacaca
    24421 tagctaaaat agctattaga aaaaatttgt ttttcataaa aactccttaa acatatttca
    24481 agtctattgt atcgataata attatcattg tcaatagata cagttacaaa tttaataata
    24541 taattttttc aaaaaaggat ctagttttta tttttagtta aattatgtct atatttttca
    24601 ttaactcatc aataaaaatt tgtttgctaa tatctctttc ttctgatttt gtttcaagga
    24661 ttattgctac atcattcata tttttaggta aataccaacc atctggctta tctgaatatc
    24721 ccttgaagcc taattgatta aaagtagtta tttgaccagt accttgattg atgttttctt
    24781 caacttcatt aaagcctata cttctcttgc ataatcccta acttgatctt ctgtccttaa
    24841 agtcattttc tattcctcgt cactaaaatt atcttcaaaa ctaataatat cattaggagt
    24901 gcaagataaa gccttacata ttctttctaa attcttaaat gtaattggtt tatcctttcc
    24961 catttgtgcc ataacatttg ttgtaagtcc tgccatagct attacatctg ttttctttag
    25021 tccttttttt gctaactgta tccataatgg tttatagtta agtgccataa tatccctctt
    25081 ttttcttcat tagatttatt taattatagc ataaatattg atttcattca atcttacatt
    25141 gatttagtga tttgttttag agaatttgtt gtgttattcc gtccttattt tgccataaat
    25201 tgttttaagt gggacctctt atccttacca tttttacctc ctaattttga gtataaaaaa
    25261 gacgatagag tttttaattt ctatcgtctg agatttacat attaaatttt catcacaaaa
    25321 taagactctt taaagaatct ttaaattcat tggtgtgctg cttacaatat ccattattaa
    25381 aatggatatt gtaagcagca caccaactat ttattttttg agttttaaac tttggtagaa
    25441 gtcttgaact ccttatattt acataactat ttgcctctat aactattatg acacgaaacc
    25501 aacaagcaag ttcaagcacc tccatatctt tattcaaatg aggactaaga tattcacaaa
    25561 ctttatcata aacctcttta tcttttttca taaaaggggc atacaactta gcaaatttat
    25621 cctaaaattt tttgttgcct ttatcaatca tttcagcgct cctttaaata taaaaatgat
    25681 cctatcaatc tttatattga gcctattttc taattgatac cttgcaagaa aggaataata
    25741 gctgttccta taccaagtag gaatgtaata aatgcagaaa gtcatatact gtcattcttt
    25801 tctattaaat cattttgaag tgtctcaaag catccatgat ggcttcttct ttttcaggtg
    25861 tacactgtgg aataatttgt ttatcctttt gagacttgtt gtaatgttct cgtaattcta
    25921 ttccacattt cttttttatc tgtgcaatat ataatgtcga aacttttaat tcaaatttat
    25981 tccaaacata ttctttgatt tgagcatatg ttgctttgct ctccgcactt gtcaaatcca
    26041 tctcatccag ctcaatttca acacttatgt gcttatcgac atcgagtttg gacaaaagtg
    26101 ctaccgtctc gacgtgatgc gtttgaggaa atagatccac cggctggact ttcttcaatt
    26161 catatcccaa ctcttggtat agtttaatat cacgcgccat ggttgcgaca ttgcaggaga
    26221 tataggcgat gcgatcggct cctgtttggg cgcttgcttt gataaagctt tctgtcaagc
    26281 ccttgcgtgg aggatcaacc aagataacgg ttggttgaat accttccttg agccatttct
    26341 tcatggcatt ttcagccgtg tcacagacat agtgggcatt agtaatcttg ttcaaagaag
    26401 cattcttctg gctattctct actgcttctg gaatcagttc aacaccgtag acttctttga
    26461 catgcttggc gactgataaa ccaatggttc caataccaga ataggcatca ataatcacat
    26521 catctttttt taactctgca aagtcaatgg ctgtttgata gagtttctcc gccatttcag
    26581 tattgacttg gtaaaaggct gggccagcga tttggaagtc atttcccaac atctggtccg
    26641 taatatagtc ttgaccataa agagtgcgcc actccttacc aaaaatcgca ttggtattct
    26701 ggtcgttgat attttgcatg acagacacaa tctctgggaa ctgcttgata acttgttcaa
    26761 tcaattggtc aacacgaaaa acttttggac gagttgtcac caaaacgacc atgatttgcc
    26821 ctgaatagtg gccacgacgc accacaagat tccgaattaa tccagactgt tccttttcgt
    26881 cataaggttt taaatcaaaa cgacggatca ggtctcgaag agctactacg acttggtcaa
    26941 tgacaggatc ctggataaag aaatcttcaa ggggcatgag gtcgtgcgaa ttcttacgga
    27001 aaaatcctgt ttccaagaca ccattcactc gacgaacggg cacctgcgcc ttattgcgat
    27061 acttgactgg atgttccata ccaagcgttt cagcaacttc tacatctgca attccagcaa
    27121 tcttgtagag actgtccttg acttgcttgg ttttaaactt gagctgttct ggataagaaa
    27181 ggtgtcctaa atccgcgatt cctgaacgca ggtaagccaa atctagatct tgattacggt
    27241 gtggtgactg gacaaggtat ttttcaactt ttccaaagcc aatcttttta ttgaccttga
    27301 ggacacgcat gagaattttt tcactcggta aagcattctc tacaaaaaag accaaaccat
    27361 ctaccttggc aactcctgcc ccttcatggg tcaaatcaac aatttcaact tctacaatat
    27421 catttttctt taacattctt ttctctttct attggccgac aaaaaagacg gcaacgttac
    27481 ggttaccatc cattatacca tgaaatttct taagaaccaa aactcttgaa gaagttgaca
    27541 agggcttgcc agagggagct taagaagtta ccaccgtcct ctagcgcctt atccgcatca
    27601 aagttaaggt tgatattttt aaaactgtcg ccagcttgtg atacgatgct ttgtttaagg
    27661 tcatttaggg ttttagtgaa atctgcattg ctgaggatat cactctttga gagattcaag
    27721 gcaaaattga tgatgatatt gatctggttt cctgttatga cctgatcaag tttgtaattt
    27781 tttaaggtat cttcaacaat cttgcggaca tcttcttctg tcagatttcc cttgctttct
    27841 ttagctttgg caagtcctga cttgatatca gctagggcaa cgtttaattt attagcatca
    27901 tagcctgatt tgtccttgtt ttcagcattg atatctgaca aagccttcaa ctcttcttga
    27961 gccaaatctt tattagcttg tggcaccttg gctccattag cctctagcga atagtaaatc
    28021 cctgctaagg cactttctcc tgtaaccgga ataggggctg ctacagtgat tttggcgtgt
    28081 tccacaccca aagttacggc tgcatttcgg tacatatcct gagttacctt agtgatgttt
    28141 tcaggtgttt caatcttgac ctcaagtggc gatttgtcac ctagcttttg aatcttggct
    28201 gatgaataca actgtaagct agagtcattg gccacattca tgattttaga ataaacatca
    28261 gatgtcatgg tcttgagttc tttggtatct gttgaggcat tgtagcccag ttttttaaga
    28321 gtttgatttt tttggtcttc agatagggaa gaacctagga catattcagg ttggacatag
    28381 gtttcatcga taactttttg aacatctgtt gctgcatgga cgctattcat agctgttact
    28441 gcccacaaga tcgcagcgct agtcagaaag agtttctttc tcatagggaa tttcctcctt
    28501 tacttcttta gagtaatata tctatcttaa agaaaactta taacaaaaac acctggtcta
    28561 gccagatgtt gaaaagagag tgaaacattt gatgatgtaa aggttaagtc gtacctgtct
    28621 agaataataa tagtttcctc catttacata gagttcagca ccgtgaaaaa tggaaatggg
    28681 gtgaatataa ctataagtct ttccagtcgt attaccaagc aagggggcaa cagtctcacg
    28741 agagtactgt ttggctagag ccaaggtatt ttccttgcca ttttgggcga taaaatcgat
    28801 ataggcaggt ccaaaattat aggcttgaac agctgtccag atatctacac ccttcttctg
    28861 cgccagatag agattgcctg tcagagtttg aatgccttgc cgaatgctag aggcattatc
    28921 attgatggtg ttggtggaac cacttgcaga ctcactagac tgcataacat cgccttcttt
    28981 tccttttgtt tcagtataaa tcatagcaag cacaagctct tcgtttgctg gggtgtcttt
    29041 ttcactcaag atttctcgca ccatgggttg ataggtcatg acttgtttga catcttgatg
    29101 aacgcggtaa gctttatagc cagcaaaaag gaagactgct agtacaagca ctcttcgaat
    29161 tcgtttaaac attatttact ttggatatcc tcgatatttt tgattaagat agagtaggtt
    29221 ccattttcgt tttggataaa ctcaacagac tcggcgtctt gatagacgtt attgggaacg
    29281 atgagctcaa ttccatttga taaggagagt ttttggtttt caaatttctt taattggcga
    29341 cttgcatcaa tttcatcaaa ttgaacaggt tctggtacgg cttctttgac ttggtcaata
    29401 aagctcaaac gagccgtcag attgttgtca aaaaggtcat tagccaattt ctcaggtgac
    29461 aattcattgc tttcttctag gttgttgaaa atcgctgatt tgaccttgga ttgaaattga
    29521 aaatcatctg tgttaaaaga ttcagcaatt ctctgggctg ttttttccag ttccttgata
    29581 gattttttag gagaaatctt aggagcgaca gcaagaagat tatctgaaaa atagttcaaa
    29641 aaagtcccgt tgtacttgat tcgtttttca atcaggtgat acttgcgact ctgaagattg
    29701 accaccaagg cctcgtcagc acccgttcca aatccaggca ggttattctg agtcagcttg
    29761 attggattat caacttctcc tccgaggtgg gtcaaggtct cccgcagggc aattcgcaag
    29821 aaagcgaaat gttctacacc ttctttagaa aattgaacaa aaatcaagtc attggtcttg
    29881 agattttcag aaatgctaaa ctcctctttc cagagattag ccagcgttac tgatgtctcc
    29941 aacaaatcgt ctgtaatatg attgaagaag ggattttctt cttcgaaaat cccagtcttg
    30001 gcttcatctg aatacacatg ttcaattttt ttacgtaggt attcttcgat ttttggagta
    30061 atattgagaa acttatctgc taagaacagc tcggtatcat ccggactgaa ctggtgaata
    30121 atggctttct taatataaat gtccataaaa gttttattcc tcgtataatg ggaaggcatc
    30181 tgtcaattct ttgactgcac ttctcacttc ttctaataca gcctcatttt ctgaattctt
    30241 aagggtttta atgatgagtt cagccacttt gcgactttct tcttcaccaa atccacgtgc
    30301 agtaatagct gctgctccga tacgaatccc acttgtcttg aatggtgaca aggtttcgta
    30361 agggattgaa tttttattta gggtaatatt gacttcatcc agcaagtttt gagcaacttt
    30421 tccgttttct acaaccttag tcacatcaac aaggaagaga tggttttcag ttccacctga
    30481 aataatacgg aaatcagggt cttgcaagaa gacatctgcc atagccttgc tgttcttaat
    30541 tacattggca gcatattcct tgaaagctgg atccaaaact tctttgaagg aaactgcctt
    30601 agcagccaca acatgctcca aaggaccacc ctgaatacca gggaaaatag ctgaattgat
    30661 tttcttagct aaatcctcat cattggtcaa aatcaaacca ccacgaggac cacgaagggt
    30721 tttgtgggtc gttgttgtag tgatatgagc gtatggcact gggcttgggt gaagaccagc
    30781 tgcaaccaag ccagcgatgt gggccatatc aaccataagc ttagccccaa cagcatctgc
    30841 aatttcacgg aattttgaaa agtcaataat ttgagaatag gctgaagcac cagctacaat
    30901 cagttttggt tttacttctt gggcttgttt caagatagca tcaaagtcca aaagttccgt
    30961 ttcaggatcc acactatagg aaagaaagtt gtaggtttga ccagagaagc taactggagc
    31021 tccgtgggtc aagtgtccac ctgctgccaa atccattccc ataaccgtat cacctggctc
    31081 aatcaaggac atgtaagccg cacagttagc ttggcttcct gaatgtggtt ggacattggc
    31141 aaatttagca ccgaaaattt cttttgcgcg ttcaatagca agagtctcta caacgtctac
    31201 tacatcagtt ccaccataat aacggcgtcc tgggtaaccc tcggcatatt tatttgtcaa
    31261 gatagaccct tgagctgcca taacagcctt ggaaactacg ttttccgaag caattaactc
    31321 gatattattt tgttggcgtt cttcttcttt ggcaatagca ttccagagat cagcatcata
    31381 tgctttaaaa tcatctttgt caaaaatcat aggtcttctc ctttattgtg tgactagtcc
    31441 attagtttga ttttacaata agaaaatcaa actaaaagat gcgaataaac cgtttctgca
    31501 ttttatcaca agtatagcca actttttcat aaaatgcatg agcacccaga cgatgattgg
    31561 cagaatttaa gcggataaac ccataaccac atcttttggc ttcttgttcc aacccttgta
    31621 gtaaactttt accgatacct tgaccttgcg cttgaggtga aactgctaaa gctaagatat
    31681 taaatcctgc tttggaatag agtgattcgt aaacttcagc gtggacatat ccaagtaaga
    31741 catgattaac tgcatcctca tagccaagta ggaaatgatg ggaatcctga gacagtctag
    31801 ctagttggct agccgtttcc tctggactaa aagtataacc caaagcctct tggttgatgt
    31861 cacatatcgc tttcacatct gtttcttgca aatctcttag catttcaaac ctcctcaaaa
    31921 gaaatctctg gcaaccgagc aagaatatct tctcgtttaa ttgcgccttg gcgtaagatt
    31981 ttcaccttgt ctccagacaa atccacaata gttgaatcct gtccagttag aaaagcatcg
    32041 tcttccagac ccagaacctc ttggtcaaaa tccttcagaa tttgttcaaa ggttacacca
    32101 cttgcctgac ctgagatatt ggcagacggc ccaatcaagg gacctgtctc tcgaattaaa
    32161 tccagtgtga tagggtgact gggcatccga aatccaatag ttgcaaggtc agaatttacc
    32221 caatagggaa ctcggtcatt ggcttcgaga ataatggtca agggacctgg caaaaaggtc
    32281 tctacaagtt tttgtagata agctggctga ttcttagaaa agtgcaagat atcctctaaa
    32341 gaggcaacat tgagattgag cgccttgtct ctaggacgac gtttgagctg gtaaacatgg
    32401 tcaactgctt tttcgtctaa ggccttggca aaaagaccat aaaccgtctc tgtaggcaga
    32461 atgacagctc cacccttttc caactcttgt ctaatcctgt ccatcatcaa ccacgaccat
    32521 cctatcttga ccaaattggt ccttgagtgt tcgaactctt ttttcaggaa gatgtttcct
    32581 aaaaagttcg ggaacacttt gaccttgctt gtatccaatt tcaaggtaaa tcttaccacc
    32641 atccttgaga tagtcttttg catcttccgc aattctacag taaatagcta ggccatcctc
    32701 gtctgcaaag agagctagat gaggctccga atgcaaaaca ttcaagccta cctctgactc
    32761 atcttcacga gagatatagg gtggattgga tacaattata tcatattttt cagaaatttc
    32821 tgcaaaacaa tcagattttt taaaaaatat attaagattt tgatcgctag cattctctga
    32881 tgcaagctct aaggcctctt gagaaacatc tgctgctgtc actgaccaat ctggtctatt
    32941 ttttgctaga gcgagagcaa tagctccact acctgttcca atatccagaa ctgagagatt
    33001 cgtctcaaga ttttcagtta gaataagctc cactaactcc tctgtttctg gacgaggaat
    33061 caaaacccgt tcatccacct ttaaatgcat tccataaaaa tctgcctgtc caatgatgta
    33121 ctgagctggc ttgtgagctg ctagttgctg gtaaatatct tctacaaatt gtttttcttc
    33181 ctctgttgtc acctcctgct ggagggcaaa aataaagtct gtaaaagata gatttttcag
    33241 actacgatag acaaaagaga ggctttccgc ttcctctcct tgtcttatca actcttcttc
    33301 aaaatttgaa aataattgag ctaatttcat tatttgttta attcttctag tttttgtgtt
    33361 tggtcataaa gcaccaaggc atccacaact tcgtccaatt taccagacaa aatcgtatct
    33421 agtttttgga gggtcaagcc gatacggtgg tctgtgacac ggttttgtgg gaagttataa
    33481 gttcggatcc gttctgaacg gtcaccagta ccgattgtcg acttacgctc agcgtcttgt
    33541 tcatcctgag caatctgagc aaagtggtca gcgacgcgtg cacggataat cttcatagcc
    33601 ttctcgcggt tcttctgctg ggtacgttct tcctgcatct caaccttgat attggttggc
    33661 aagtgaacga tacgaacggc agtcgcaacc ttattgacgt tctgtccacc agcaccagag
    33721 gcgtgataga tgtcgacacg aaggtctttt ggatcaatgt cgtattcaac ctcttcaact
    33781 tctggcataa caagaactgt cgctgtcgaa gtatgaacac ggccttggct ttctgtcaca
    33841 ggaacacgtt gcacacggtg ggcacctgat tcatacttaa gcttagagta tacagactga
    33901 cctgaaacca tagcaaccac ttctttaaaa ccaccgacac cattcataga ggcttccatg
    33961 acttcaaagc gccaaccttg ggcttccgca tacttttggt acatagttag caaatctcca
    34021 gcgaaaagtg ccgcttcgtc tccaccagct gctccacgga tttcaaggat gatattcttg
    34081 tcatcgtttg gatcctttgg aaggagcaaa attttcagtt tttcttcata ttcttctttt
    34141 tcagccttgg catctttgag ttcttgcttg gccaattctt ccaagtccgc atctccgcct
    34201 gattccttaa tcatctcttc ggcatcgacg atattttgaa ggacttgttt atactcacgg
    34261 taggctatta cggtgtcacg attggaagct tcttcttttg aaagctccat aaaacgcttg
    34321 gtgtctgaaa cgacatcagg gtcactcagc aattctccta gttcttcata acggtcttct
    34381 acagcttgta gttgatcata gatgttcatt ttttctcctt atttctcaat tgttaaatca
    34441 tagattgcta ctacttcatt ctcggatatt tccccagttt ctttaaatcc ataactgagg
    34501 taacaaaatc ttgcctgttc attttctggt tcataagaca accaaagttt attgcttaaa
    34561 cctgctggcg ctgttcgaac atagtctagt actttatcca taattggttt aaaatatcct
    34621 tgattttgaa aattcttatc aatcataaaa cgaaatagta aataatttcc actactaatt
    34681 ccgatctttt tatcataagc tatcatcaca aaacctataa ttgcatcatt atcataaact
    34741 gccaatggag ctacaaaatc tccattttta gtgtagacgt atgcttcagc taaactaatt
    34801 gcgttggttg caatgaattg tttttgatat tccttgacat ccaaatttaa aacatcaaaa
    34861 taattttcca ttgtaacatc tcttagttca attgtcatag ttttgctcct tgttagaggt
    34921 tatcattggc gcaaaataat gtttacggca aaccgagata taggtttcat taccaccaat
    34981 ctggatctgt tctccatcgt aaacgggcag tccatcctgt gttcgcaaca ccatggtcgc
    35041 ctttttcttg caatactgac agatggtctt gatttcgtca atcttgtctg ctaaaagcaa
    35101 gagatatttg gaaccttcga acaattcatt gcgaaagtca tttttcaagc caaaagccat
    35161 gacgggtatg tctaactcgt ccacaacacg agctaggtca taaacatggt ggcgtttgag
    35221 aaactgggct tcatcgacca aaacacagta aggtttttct ggtaggtctc ggatatagcc
    35281 aaagatatcc gttgtttcct caatcgcaag ggcagggcgt ttcatgccaa ttcgactcga
    35341 cacatagcca acaccgtcac gcgtatccag agccgaggtc ataatcacaa caccttttcc
    35401 ttgctcctcg tagttatagg ccactttgag aatctcaatc gttttaccag agttcatggt
    35461 cccataacga tagtacaact gtgccatgtt tcttgcttca cgtccatttc taaatttttg
    35521 ctacattcta gtatatcata attttcttaa gctttaaacg gcaaaatgtg gtaaaatgga
    35581 agaaatcaaa actagtggag gaagctatta tgccatttgt acgcatcgat ttatttgaag
    35641 gacgcacgct cgagcaaaag aaagctcttg ctaaggaagt aacggaagcg gttgttcgca
    35701 acactggagc acctcaatct gctgttcatg tcatcatcaa cgacatgcca gaaggaactt
    35761 atttcccaca aggggaaatg cgcaccaaat aagctagctt aagcagaatt gcttaggctt
    35821 tttcaatctc caagtagcac ccattgaaga aatagtctaa atttgttaca atttgaaaag
    35881 agacttggaa aattccaaga aaagagcaat taattaaagg aaacattatg attacacgtg
    35941 aatttgatac catcgctgct atctctactc cactaggtga aggggctatt ggtattgtcc
    36001 gcctgagcgg aacagacagt tttgctattg cgcaaaagat ttttaaagga aaagacttga
    36061 acaaggttgc cagccacact ctcaactacg gtcacattat tgatcctctg actggtaaag
    36121 tcatggacga ggttatggtt ggggctatga agtctccaaa gacctttact cgtgaggata
    36181 ttatcgagat taacacccac ggtgggattg cggtgaccaa tgagattctc cagctagcta
    36241 tccgtgaagg agctcggttg gcagaacctg gtgaatttac caaacgtgcc tttttaaacg
    36301 gtcgcgtaga tttgacacag gccgaggcgg tgatggatat catccgcgcc aagacagaca
    36361 aggccatgaa catcgcggtc aaacaacttg atggttccct ttctgatctt atcaataata
    36421 tccgtcaaga aatccttaat acacttgccc aagttgaggt caatatcgac tatcctgagt
    36481 atgacgatgt tgaggaagcc actactgctg ttgtccgaga gaagacaatg gagtttgagc
    36541 aattactaac caagctcctt aggacagccc gtcgcggcaa aatccttcgt gaaggaattt
    36601 caacggctat cattggacgt cccaacgttg ggaaatcaag ccttctcaac aacctcttgc
    36661 gtgaggacaa ggctatcgta acagatatcg ctgggacaac acgagatgtc atcgaagagt
    36721 acgtcaacat caatggtgta cctctcaaat tgattgatac agccggtatt cgtgaaacag
    36781 atgacatagt ggaacaaatc ggtgttgagc gttcgaaaaa agccctcaag gaagccgact
    36841 tggttctact agtgctaaat gccagtgaac cactgactgc gcaagacaga caacttcttg
    36901 aaattagcca agataccaat cgcattattc tacttaataa aaccgacctg ccagaaacga
    36961 ttgaaacttc gaaactacct gaagacgtta tccgtatttc agtccttaaa aaccaaaaca
    37021 tcgacaagat tgaagagcga atcaacaacc tcttctttga aaatgctggc ttggtcgagc
    37081 aagatgctac ttacttgtca aacgcccgtc acatttccct gattgaaaaa gcagttgaaa
    37141 gcctacaagc cgttaatcaa ggtcttgagc tggggatgcc agttgatttg cttcaagttg
    37201 acttgactcg tacttgggaa atcctcggag aaatcactgg ggatgctgct ccagatgaac
    37261 tcatcaccca actctttagc caattctgtt taggaaaata agaaaaatcc atgatccttc
    37321 attcggtcat ggattttatt gtctttatta gtaatctggt cttaagaccc ctgttacagt
    37381 tgccttagtt gcttcgtagt cgccatctac gacaaccttg ataatgcgtt tggcatcttc
    37441 ttctggtgct ggaataagag gtagacgagt gggtccagct tcaaatccca tatagttaag
    37501 aactgcctta actggagcag gacttggata agagaagaga gcattaacct taggaatgaa
    37561 tttacgctga attgctgcgg ctttcttcat atcgctttct gcaatggcag taaacatctc
    37621 gtgcatttca tccccatttg tatgagaggc aacagaaata accccatccg ccccaaggtt
    37681 catggcatgg aaagcatctc catcctcacc tgtataaatc aaaaactctt caggcttgtg
    37741 ctcaatcaag taagccatat tagccaagct agtacattct ttgacaccga taatatttgg
    37801 atggtcagcc aaacgaagca tggtttctgg agtcaattcg accactacac gccctggaat
    37861 gttatagata ataattggta ggtcagaagc atctgcaata gccttaaagt gctgatacat
    37921 cccttcttga gaaggtttgt tgtagtaagg aacaatagca agcccagctg cgaaaccacc
    37981 aaattccgct acttctttga caaactcaat agagtcacgc gtatcattag tacctacacc
    38041 cgcaatcaaa ggaacgcgtc cattgacaac cttttgtaca gccgcaaaca actccaactc
    38101 ctcatcgtgg gtcaaagttg gactctcagc agtcgttcct gcgagaagaa ttccatccgt
    38161 atgatgggcc aataaatgct caatcaaggc tggaatagca tcaaagttaa tggaaccatc
    38221 ctcatggaag ggggtaataa aggctgtaat gattttacat tcttttaaat cttgataaga
    38281 cacgaaaaca cctctctatt tcaaagaagg agttcatctg aactcctaaa cgatatgact
    38341 attttaattc aaatttcaat tcggctgttg gacgaaccaa tccacgttca tgaagagttt
    38401 cagcaatctg aactgagttc caagcagcac ctttgagaag gttatctgaa acaacccaca
    38461 tgtgaattcc tttttctgca tccaagtctt tacggatacg accaacaaag gtatcacgcg
    38521 aaccaactgc attgatagct tgaggataga tttgatgagc tacatcatct tcaagaacag
    38581 cacctgggaa ggctgcgata gctgctttta cttcttcgat tggagccact tcttttgttt
    38641 cgatataaac agactcagag tgagctgaca agactggaat acgcacacat gttgcagata
    38701 ctgcaatgct atcatcttcc ataattttct tagtttcctt ggtcatcttc atctcttcgt
    38761 aagtgtaatc attgtcagtg aagacatcga tttgtggaag agcattgaag gcgataggat
    38821 aatgtttctt gtcaccgcct gaaggtaaga tttccgcatg caaatcacgt ggtttcgctc
    38881 catcattcaa gacctcacga agttcacgtt gcgtctcaag aattgctccc ataccagcac
    38941 ctgaaacggc ttgataagtt gaaacaatga tacggtccaa gccccatttt tggcgaactg
    39001 gctcaagagc taccatcatt tggattgttg aacagttagg gcaagcaata atcccgttgt
    39061 gggcatcaag tgcgtgagca ttgacctctg gaacaaccaa aggaacgtct ggattttgac
    39121 ggaagtaaga tgtattatct actactactg cgccagcttt aactgcgtat ggtgcatact
    39181 tagctgatgt cgaaccacct gctgaaaaaa gagcaatatc aactccttca aaagctgttt
    39241 cagtcgtttc ttcaatcgta atatcttgat ctttaaattt caatgtcttg cccgctgaac
    39301 gtgcagaagc aaggtaacgg attttatcga ttggaagtgt tgattcttcc aacattttta
    39361 tcatctgagc accgacagca cctgtcgcgc cgactacagc aactgtatat cccataaata
    39421 acctctttcg gaattttcta aaaatttcta taatagaagt attatactac tttttccatg
    39481 aattgcaaag ctttttcatc attttttgga aaataaaaat cccagtcgct agactaggga
    39541 ctaagaggca tcttcatgtg atgagcaggt tcacacaact catcaaggtc cgctcctgcg
    39601 ttatgacctc cttatgctca atagtagtcc gaagactacc tatcgactca tcgcatattc
    39661 tatattacta gagatacttg attttgtcaa taagaaattt tttcgatcga gtataacaaa
    39721 aaactctcgt attcaagagt ttccctatac atatcatgct aattgccggg attgaaccgg
    39781 cgacctcatc cttaccatgg atgcgctctg ccaactgagc taaatcagct tacttaagaa
    39841 gtatactata ttcagaaaaa cttgtcaagt ttccttagaa attttccata ggaaaaagcc
    39901 aggtaagaac tacctagctt atcttcttct atttacttaa atcaattcga cgaccaattt
    39961 taccaataat aatcgctcca ataatcaatg aagcaaattc accgattcct gttgtaaacc
    40021 aagtaaggaa gaatggtaat tctgctacaa tatttaactc tgcagcgata gtaaacatgg
    40081 aaattgaaaa gaggattgaa aagaagaaat gatcttttcg aatcaatccg ttaaagaggt
    40141 aatccttgct atattttgca aaaagccaaa cacctaaact gaggaatact aaggttgaac
    40201 caccaccaac aaagacatct agcagtccga agctaaagaa attagcaatc atacaaccga
    40261 tggtaactcc gatgatgtac ttaggattgt aaaaagccat aaagttcatc atttctgaaa
    40321 tacgaaactg ataagcacca tagctgatgg catttagggg cggtgtgaca gtcaaaacga
    40381 cgtagatagc agcgacgatt gcaatatctg caacatcacg aatagttaat tttttcatct
    40441 tttctccttt ggcggttatc cgcgtgtaat atgcttggtg aaagaagcta agcaccaagg
    40501 gttgattcat tcaaccttac cagtatagca caatagcctg ctttatgcta tacttaaagc
    40561 atgaaaaaac ctattcaaaa attttttaac aatgaaatct tagcctatct cttttttggc
    40621 cttgcgacaa ctctagtttc gattctctca cgactagtca tttatcaact aagtcatcag
    40681 gaactccttg ctacggcctt ggcaaatatt atcggtatct tatttgcctt tatcacaaat
    40741 gatacgattg tatttaagca aaaaaagaaa aatagactta tccgtttagt gaaattttct
    40801 cttgcccgcc tttctacttt tctgttagac ttgtttttaa cttttctctt tgtaacccaa
    40861 tttcctcaca tcatagggca attcgtaact gaaaacattg ataagataaa tgctattgaa
    40921 acaataattg cacaaatatt cattattatc atcaattata tcttgagcaa ggtctatatt
    40981 tttagaaaat aatgctccat ttatgagcct tttaattgcc ttctataatg atttaggata
    41041 caatgaaaca cgaaacattg aaaggaaaac agtatgttaa aaaatctaaa atcgttcttg
    41101 cttcgaggaa atgttattga ccttgctgtc ggtgttgtca ttgcctctgc ttttggtgct
    41161 atcgttactt cacttgtaaa cgacattatc actcctctta ttttaaatcc cgctttgaaa
    41221 gctgctaaag tcgaacgtat cgctcaactt tcttggcatg gagtcggcta tggtaacttt
    41281 ttaagtgcta ttatcaattt tatctttgtg ggtaccgccc tcttctttat tatcaagggc
    41341 attgaaaaag cacagaaact gactggcata aaggaagaaa aaactgccga aaaaaaacca
    41401 accgaattgg aagtccttca agaaataaaa gctctccttg agaaaaaata atcgattaaa
    41461 aggatctagc gcaaagctaa atcctttttt ctttactctt tgggtaactt gcctgctttt
    41521 tcaagcattt tcttgatcag ataaggcatc ttaacatttt cacgaccttt tttctcaatc
    41581 aattttttca caaattctgg catttgtaaa tcttgagatt cggctaagat atttttagtc
    41641 tcatctgaag gcactaactc atcaaaggtt tcttcttctg ggagaaattc cttaaactct
    41701 tgattttcat tgactctaac tgtattgacc aaggcatcaa tcaaacgaga atctgtattt
    41761 ggcattggtg gacgatggta gtttacccca aattcctggc ataagtcata acattccaca
    41821 tcattgtcaa acaagacctc aatatgctca ctgatgaaac taataggtac aaaaatataa
    41881 tggtctggat gttctgtctg ttctctgaga tactccaaaa catctggttt aatccatgga
    41941 ataccaatat cactctcact ctgccaagtg ttggtatatt gttctgaact caagcccagt
    42001 ttttcagcga ctaacttgct attttcgaaa atttggtcta tataaggatc accaaagtcc
    42061 aaggcaaaaa taggcacact atgggctgaa aagatgactt taaagctgtc ttgctttact
    42121 tcttctttta aaatcttagc aatttcatct gcccaatagt ttaagagcgc ttcttcctga
    42181 taccagtcct taatgaccaa aaattgaatt tgtttgcttt ctaaaaattt ttcatagccc
    42241 atgacagagt agaaagaata atggggctcc aaaatcaaac aaatacactg ttcaattccg
    42301 tctgcttcca tttgaccgat cacatctgga ataaagggac tggaaaactt attagcaaag
    42361 tagacactgt attcattccc cagcctagct tctaccaagg caacctcttg acgggtaatt
    42421 ttttgcagag gcgtgcctcc aattcgtaca taattatcat agagagtctg aatctcgtgg
    42481 tcttggggtc tcaccccacg acgaatattt gtgaaaaaat cagctacacc ttcaaaggta
    42541 atctcttctg gtgaaccgaa ggtcatcatt aaaattgctt ttttcatgac tgcttccttg
    42601 tgatgttttt atcaagttta ttttatcatt aattcatcga taagtaaacg ctagcatagg
    42661 gacattctca atcttctgtc ttttgttttt ctcttctttc tatgatacaa tggaaaaaat
    42721 aaattcaaaa ggagtttttt tatgacttat ccaaatctct tggaccgctt cttaacctac
    42781 gttaaggtca acacgcgctc tgatgaacac tctactacta ctccaagtac acagagtcag
    42841 gttgacttcg caacaaatgt cctaattcct gaaatgaaac gtgttggact gcaaaatgtt
    42901 tactatctac cgaatggttt tgctattgga accttgccag ccaacgatcc gtctttaaca
    42961 cgtaagattg gttttatatc gcacatggat actgctgatt ttaatgctga aggagtcaat
    43021 ccacaggtaa ttgaaaacta cgatggtggt gtgattgaac tagggaattc tggtttcaaa
    43081 ctcgatccag ctgacttcaa gagtcttgaa aaatatccag gacaaacgct catcacaaca
    43141 gatggaacaa ccttgctagg tgctgatgac aagtcaggaa ttgctgaaat tatgacagcc
    43201 attgaatatc taactgctca tcctgaaatt aagcactgtg agattcgtgt tggttttggt
    43261 ccagatgaag aaatcggtgt tggtgccaat aaatttgatg cagaagattt tgatgtggat
    43321 tttgcctaca ctgttgatgg tggtccacta ggtgaacttc agtacgagac tttctcagcc
    43381 gctggtgctg aattgcattt ccaaggccgt aatgtccacc ctggtactgc caaagggcag
    43441 atggtcaatg cccttcagct agcaattgat tttcataatc aacttccaga aaatgaccga
    43501 cctgagttaa ctgaaggtta ccaaggtttt taccatctaa tggatgtgac aggtagtgtt
    43561 gaggaggcgc gtgcaagcta catcattcgt gattttgaaa aagatgcctt tgaagcgcgt
    43621 aaagcatcca tgcaatctat cgctgataag atgaatgaag aacttgggag cgaccgtgtc
    43681 actctcaact tgacagacca gtactacaat atgaaagaag tcattgaaaa agatatgact
    43741 ccaattacca ttgctaaagc cgttatggaa gatctaggta tcacgcctat tatcgaacca
    43801 atccggggtg gaacagacgg ctctaagatt tcctttatgg gaatcccaac tccgaatatc
    43861 tttgcaggtg gcgaaaatat gcacggacgt tttgaatacg ttagccttca gactatggaa
    43921 cgtgcagttg ataccatcat tggcatcgta gcttataaag gctaaaaaga cgaggtggct
    43981 cagctacttc gcctttcttt ttattctact ggtttttctt gatttccagt agttgtagaa
    44041 gattctgttg tttcattttc tgaagttgat tcagcaggtt tagaatctct tgtattgctt
    44101 ggtttgtttt cgtcgctagc agtttcaatg ttagattctg cagttgcgtt tggttggttc
    44161 tcagcactgg tgttatcacc atttgcttca gcatttcttg ctggacttgt ttcttcactt
    44221 gcgctagctt ttgactggat ttgatgattc aaaactagaa tagcttttgt cggttcaagt
    44281 aaagctgttt tgtctttact cttagcagaa agttgatcta ataatgcatc caccttatca
    44341 aagtccgcat cagatccatt attactttct aaataagagt gaagcgacat gagaatatcg
    44401 tagagttttt gatagagtac aagtgtctga ggatcttgct cagcattttc cttttcttgt
    44461 tgaagggcgc tagcgatacg agtcaaaaca tcttttacct gactgtttac ttcatccaag
    44521 tctgcatcag ccttgtttgt ggcagctttt agattttcta cttcttctgc caaggattgt
    44581 ctgattcctt cttcatggat ttgttccaag agttgatttg ccttgctcaa aagactttct
    44641 acttcttcct tgctatctgt cgcagattat tggttgccat ctaccatgta ctcctaaaac
    44701 aggagagtta taatccaaga ttacaaggcc ttacagaaat aagaaatcca gataagacaa
    44761 tgttcgtcca agacgctatt cgcttcgcac agcagcacgg attcaatatg ctttaatttt
    44821 aaagtttagg tgtcaagacc tctttttagt gtgcccaaaa tttagagaag taatcaatca
    44881 actaactttt atttttttca aactttcagt aaactgacct aaagctaact caatctgtct
    44941 ttgttcgata ggcttgtctt tgtagatgct tctgctatca gctagaagtt gatctacttt
    45001 tgccaagact gccttctcat caaaagttcc aggttgatag ttggattgca gggatggaat
    45061 cttgtttttc aaagccgctt catatccctt agtttgaacc ttgatgtagt gattgtggtc
    45121 gccacgagga atcacaaaac cttctgaatc ttcacttata attcgattgg catcaaaacc
    45181 atgaccatct tcttcctcat ggtggacatg tagtgacgga ttacttaata cagaactaga
    45241 agaacttcct accttttccg tgttagagtg tgatggggga ttgttaagag atgacttagg
    45301 aatatagtga tagtgacccc atgtcttact atataagcat cacctgtatc tctgacaata
    45361 tcattagggt taaagacata accatcatct gctgcagaaa caccattatt cggtgtcacc
    45421 gacaaagatt gactgagagc tgtagtattc tctgataatt atacttttgc agctgctaat
    45481 tcacctgccg acaagtcact ctcaggaatg aaatgatagt gaccaccatg tggtactata
    45541 gtagattgaa atagaatatg agcaaattga taaggggatt ttaaagtaat ttctaacaat
    45601 gatttagaaa ctatgatgtg ctattctaaa ttcaactcac tatatataac catcatcggt
    45661 agtataacgt ccctgtaatt ttgctacaga tacttctgca ctagctcctt tatcgtcttt
    45721 accatgttct tgtttttggc gattgatttc atcttttatt cgtacatttt ctgcatgagc
    45781 ttgatcttta aggtaaacat aatactttcc atctacctta ataatatatc ctcccttaac
    45841 ctaactgacg atatcttgat ctttcggctg atagttgggg gctttcatta atagctcttc
    45901 actaaagagc gcatccaaag gaactttacc attatagtag tgataatgat cgccatgaga
    45961 agttacataa ccttgacctg taatcttaat aacaatttgt tttgcttgaa ttccttcttt
    46021 ttgactaacc tagtctggag tcaaattttc agtcttctta gtgtctttat tactgtttac
    46081 atatgaaaca cgatttttat ctgtattagc ctgttagcta tgttggttca gagcataaac
    46141 acacagactt aaggaaagga taacaacaga tccagctact atatatttct ttttaaattt
    46201 cataattacc tcatttctat aattatttat atgatgtctt cattattaaa tgattaaata
    46261 aattgattaa ccaattaatt aactagtaaa tattccgcct ctttttaagt tgtatgtcaa
    46321 gaaattttat atattaataa taaaatgaaa ttctcccaaa gtcagagttt tatttctaac
    46381 ttttgagaga acttcatttt tgattcagac tttttctact gctattcctt acgctatgag
    46441 atcagataaa ttctttttta tcacttctcc acttggcaat cttaattcaa tcgttccatc
    46501 catattgaat ataacactat ctaagcctaa tccgtaacta gctgtaaatt tttctaattt
    46561 ttcttgtaca ggatctactg ctggagcttc ctctaatgct ggatctaaca tagggtcact
    46621 ccccacattc ccttctggat tcaacattcc attatccgtt gagttttctg gttttacagg
    46681 tttttcgttt ggtgcctctg gtaaagaatc tgctggttta ttttctgttg gttggttctc
    46741 aactgttcca atagatactt ttccattttc agatggttta ttttcaccat ttccttgagg
    46801 tgcttctcct gtaaaatctg ccatattctt tttaatgact tctcccgatg gtaaatataa
    46861 ttcaattgtt ccgtccatat taaacaagac attttctagc ttcatcccat aactttcagc
    46921 aaattttgct actttttctt gtacaggatc cactgtagga acttcttcta acgttgaatt
    46981 actagtacta ttcccagttt cagaaagttt ttctttttct accttctcac tagtctttgg
    47041 ttcttctacc ttttcatcaa gttttgagtt ttcttgtgct ttattccttt taaattgtgg
    47101 tagaatactt ggtttatcag tttgattttc tttttccaag ataggtactt ccacaatata
    47161 agtcgattga ttgtccaaat aagcatttgc catgaaggtt acaggaattt tatttccggc
    47221 cgttctggtt gttccttggt ttaatttcgg aatcggtaat ttgatttcac caactttata
    47281 gttattttct aaataagcat ttccatgaaa ttcatcaaac actctgacta aagcatcagt
    47341 tcctttaggc actgcaaatt gagggttcac tcttaaataa gtatcccctg catggaaagg
    47401 atagaaaatc gtttgactgg ccattttgta agctaaagag gttggaactg taaatgtacc
    47461 atcataactt acttctggat aatcttttga agcgatagta tacttaaatg tttgtcctgg
    47521 taaataaggt tgatctaatt caaagtttgc aatattccct actccttctc caaatacttt
    47581 accagatact ttctccaata cttttccatc tggtgttatt aattttacta gcatattgat
    47641 acctaatttt ttctccaatt caggcggaaa actaaaagaa acgcgttttt gaccattggc
    47701 tagagtaaag ttttgattat taaacgtact attttttaac aaattaacaa cattcgttaa
    47761 ttcttctcca gtataaactt tattcccttc ttttttagca actccttctt cgggtttaaa
    47821 cagttcatag ttactgtgag aatgaccaat tccaaccggt ttatgttcat caatcggatc
    47881 tgcatgatgg tgatctccat gcggataaat aatcgcattt ttttctttat tcacgacaat
    47941 actttcacgt ttgacaccat attgtttcat aatgccagca attttttctt cgattttttt
    48001 atctaaatct ttcatttctt tggcattact tggataatcc tgttcatgag atgacaaaga
    48061 atctaatcca ttatgactag ttttaacttc ctctaaatgt ttttgcgcag ccttaatttg
    48121 ctcttctgtc aagtccttct tgaagaaata atgattgtgg tctccgtgac tcatgacaaa
    48181 acctgattca tcttcagcga taatacgatt agcatcaaat ccgtatccat cttcttcatg
    48241 tttctcatgt gaagttcctg gattgattgg aagagatgga gaaggtgttg ctagactatt
    48301 gtttggaaga gtcggttgcc caatttgatt tgattttgga atgtaatgga aatgatcacc
    48361 atgtcttaca atataagctg tagccgtttc ttcaacgata tcttttggat taaaaatata
    48421 accatcagat gctgaagaga gctccttact tgtcgttaaa gaagaagaat tgcttgaaag
    48481 actgcctaga ctagacacta cttcattagg ttttgcattt gtagaaactg tagaaccagt
    48541 tccactgata ggcaccattc tggcaatctt ttcttctaag gcagaaagct tgctgtaagg
    48601 aataaagtgg taatggtcgc catgcggaat cgcaactcca tttggtgtac gactgataat
    48661 cttagcaggg tcaaagacca ggccatctga ttcactgtaa cgttgggcgc taggtgaatc
    48721 atagagttcc ttcaaaagac tctggagatt ttcagattta tttgctggct tgctagttga
    48781 tccttttgct acagattgcg tgttattgtc actagctgtt gaagaatagc ttaactgact
    48841 cggttgcata ttttttccag ccagatgtgc tttagctgct gctaattcac tagcagataa
    48901 atcgcttttg ggaatgtagt gatagtgacc tccatgagga acgatataag cattacccgt
    48961 atcttcgata atatcagctg gattaaagac ataaccatca tttgtcgtat atcgtccctg
    49021 agaccttgct acagcaacat tagagttaac cttctcatta tctttgacat gttcttgttt
    49081 ttgacgattg atttcatctt tagttcgaac attatcagca tgagctgcat ctttcaggta
    49141 gacataatat tttccatcga ccttgatgat ataaccaccc ttgacttcat tgacaatatc
    49201 agcgtcttta agttgatagt ttagatcctt catcaagagt tcttcactaa agagggcatc
    49261 ataaggaact ttcccattat agtaatgata gtggtcaccg tgtgacgtta catagccctg
    49321 atctgtaatt ttgattacaa tttgctcagc ctgaattcct tctttctggc taacctggtc
    49381 tggtgtcaag ttttcacttt tctgacttga ctggctgcca tccacataag agacacgatt
    49441 attgtcctta ttttcctgcg aacgatgctg gtttagtgca taggcacata gactcaagga
    49501 tacgataaca gctgatccag ctgctatata ttttttacta aatttcataa atccctcatt
    49561 tcaataaatg atgaagtttt ttctcaactt cttttacttt attaaatagt tttctaaacc
    49621 ggttatttaa ccatttaatt aaccatttaa ttaaccagta aatagtttac tatttaaaat
    49681 tacttttgtc aagtttctgt tacgtttttc taaaaaagag aagtaacacg aaaggttact
    49741 tctccataaa atatgctcca ttcattttac tactgtatag gagccggttg actttttttt
    49801 aacaaagcca agagactatc tacttctgct gaaatagtgt tattatcttt cgttccgaga
    49861 agaagactac tttttagacc agtcaatgtc tccatagcat tttgtctaat actaggatct
    49921 gttacttttt ctagcaaggc ctccgcatct gctatcttag cgttaataac agaatgctct
    49981 acttgaggaa tttcagcctc atctgtagta tcttcagctt cttcctctgt ctcttccgta
    50041 tcagtgcttg gtttataaag attatctgct gaaggattta aaccagcgtg attctctttt
    50101 tcatcagatt cagggtgagt tggctcactt acttcatcat gtcccttatc ttcatcaggt
    50161 ttactatctt ggtctgcctt atttttacga acatggtc
//
LOCUS       DAVEHY010000015        48927 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVEHY010000015 DAVEHY010000000
VERSION     DAVEHY010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.015"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(1..232)
                     /locus_tag="VUZ44_001006"
                     /pseudo
     CDS             complement(1..232)
                     /locus_tag="VUZ44_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(363..1235)
                     /locus_tag="VUZ44_001007"
     CDS             complement(363..1235)
                     /locus_tag="VUZ44_001007"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU0319940.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1471..2781
                     /locus_tag="VUZ44_001008"
     CDS             1471..2781
                     /locus_tag="VUZ44_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU0319941.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(3147..3341)
                     /locus_tag="VUZ44_001009"
     CDS             complement(3147..3341)
                     /locus_tag="VUZ44_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU0319942.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(3801..4529)
                     /locus_tag="VUZ44_001010"
     CDS             complement(3801..4529)
                     /locus_tag="VUZ44_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU0319943.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            4687..6096
                     /locus_tag="VUZ44_001011"
     CDS             4687..6096
                     /locus_tag="VUZ44_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU0319944.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            6114..7409
                     /locus_tag="VUZ44_001012"
     CDS             6114..7409
                     /locus_tag="VUZ44_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU0319945.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            7414..7722
                     /locus_tag="VUZ44_001013"
     CDS             7414..7722
                     /locus_tag="VUZ44_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU0319946.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            7719..8027
                     /locus_tag="VUZ44_001014"
     CDS             7719..8027
                     /locus_tag="VUZ44_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU0319947.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(8935..11586)
                     /gene="adhE"
                     /locus_tag="VUZ44_001015"
                     /gene_synonym="adhC"
     CDS             complement(8935..11586)
                     /gene="adhE"
                     /locus_tag="VUZ44_001015"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU0319948.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLNQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(11886..12296)
                     /locus_tag="VUZ44_001016"
     CDS             complement(11886..12296)
                     /locus_tag="VUZ44_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319949.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(12298..12726)
                     /locus_tag="VUZ44_001017"
     CDS             complement(12298..12726)
                     /locus_tag="VUZ44_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU0319950.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            complement(12772..13071)
                     /gene="yajC"
                     /locus_tag="VUZ44_001018"
     CDS             complement(12772..13071)
                     /gene="yajC"
                     /locus_tag="VUZ44_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU0319951.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(13188..15164)
                     /gene="tkt"
                     /locus_tag="VUZ44_001019"
     CDS             complement(13188..15164)
                     /gene="tkt"
                     /locus_tag="VUZ44_001019"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU0319952.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEEGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGENIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            complement(15278..16369)
                     /gene="ulaG"
                     /locus_tag="VUZ44_001020"
     CDS             complement(15278..16369)
                     /gene="ulaG"
                     /locus_tag="VUZ44_001020"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU0319953.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(16481..18154)
                     /locus_tag="VUZ44_001021"
     CDS             complement(16481..18154)
                     /locus_tag="VUZ44_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU0319954.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            complement(18333..19037)
                     /locus_tag="VUZ44_001022"
     CDS             complement(18333..19037)
                     /locus_tag="VUZ44_001022"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU0319955.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(19039..19902)
                     /locus_tag="VUZ44_001023"
     CDS             complement(19039..19902)
                     /locus_tag="VUZ44_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU0319956.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKSCDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(19906..20571)
                     /locus_tag="VUZ44_001024"
     CDS             complement(19906..20571)
                     /locus_tag="VUZ44_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU0319957.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            complement(20588..21073)
                     /locus_tag="VUZ44_001025"
     CDS             complement(20588..21073)
                     /locus_tag="VUZ44_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU0319958.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(21150..21431)
                     /locus_tag="VUZ44_001026"
     CDS             complement(21150..21431)
                     /locus_tag="VUZ44_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU0319959.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(21454..22911)
                     /locus_tag="VUZ44_001027"
     CDS             complement(21454..22911)
                     /locus_tag="VUZ44_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU0319960.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIVAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFWLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(23042..23665)
                     /locus_tag="VUZ44_001028"
     CDS             complement(23042..23665)
                     /locus_tag="VUZ44_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU0319961.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(23716..24702)
                     /locus_tag="VUZ44_001029"
     CDS             complement(23716..24702)
                     /locus_tag="VUZ44_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU0319962.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(24721..25545)
                     /locus_tag="VUZ44_001030"
     CDS             complement(24721..25545)
                     /locus_tag="VUZ44_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU0319963.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            complement(25520..25891)
                     /gene="rnpA"
                     /locus_tag="VUZ44_001031"
     CDS             complement(25520..25891)
                     /gene="rnpA"
                     /locus_tag="VUZ44_001031"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU0319964.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(26040..27230)
                     /locus_tag="VUZ44_001032"
     CDS             complement(26040..27230)
                     /locus_tag="VUZ44_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU0319965.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(27281..28234)
                     /locus_tag="VUZ44_001033"
     CDS             complement(27281..28234)
                     /locus_tag="VUZ44_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU0319966.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(28295..28889)
                     /locus_tag="VUZ44_001034"
                     /pseudo
     CDS             complement(28295..28889)
                     /locus_tag="VUZ44_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            complement(29026..29439)
                     /locus_tag="VUZ44_001035"
     CDS             complement(29026..29439)
                     /locus_tag="VUZ44_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU0319967.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            complement(29417..29878)
                     /locus_tag="VUZ44_001036"
     CDS             complement(29417..29878)
                     /locus_tag="VUZ44_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU0319968.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIHRVEKEKS"
     gene            complement(29841..30101)
                     /locus_tag="VUZ44_001037"
     CDS             complement(29841..30101)
                     /locus_tag="VUZ44_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319969.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(30106..30534)
                     /locus_tag="VUZ44_001038"
     CDS             complement(30106..30534)
                     /locus_tag="VUZ44_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU0319970.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(30503..30829)
                     /gene="comGC"
                     /locus_tag="VUZ44_001039"
     CDS             complement(30503..30829)
                     /gene="comGC"
                     /locus_tag="VUZ44_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU0319971.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLGKNEEASLNKLQADGRITEEQAKAYKEYHTKNGGA
                     NRKVND"
     gene            complement(30831..31847)
                     /locus_tag="VUZ44_001040"
     CDS             complement(30831..31847)
                     /locus_tag="VUZ44_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU0319972.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMRVFSILARLPFLGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQIMQEQGSHLFKEIGQDLAQSLQNGREFSQTIATYPFFKKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(31795..32736)
                     /locus_tag="VUZ44_001041"
     CDS             complement(31795..32736)
                     /locus_tag="VUZ44_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU0319973.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(32811..33176)
                     /locus_tag="VUZ44_001042"
     CDS             complement(32811..33176)
                     /locus_tag="VUZ44_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU0319974.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(33327..34385)
                     /locus_tag="VUZ44_001043"
     CDS             complement(33327..34385)
                     /locus_tag="VUZ44_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU0319975.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(34548..35699)
                     /gene="nagA"
                     /locus_tag="VUZ44_001044"
     CDS             complement(34548..35699)
                     /gene="nagA"
                     /locus_tag="VUZ44_001044"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU0319976.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(35852..37669)
                     /locus_tag="VUZ44_001045"
     CDS             complement(35852..37669)
                     /locus_tag="VUZ44_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU0319977.1"
                     /translation="MRIKWFSLIRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(37767..38909)
                     /gene="tgt"
                     /locus_tag="VUZ44_001046"
     CDS             complement(37767..38909)
                     /gene="tgt"
                     /locus_tag="VUZ44_001046"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU0319978.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKTDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            39039..39896
                     /locus_tag="VUZ44_001047"
     CDS             39039..39896
                     /locus_tag="VUZ44_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU0319979.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(39924..40568)
                     /gene="pcp"
                     /locus_tag="VUZ44_001048"
     CDS             complement(39924..40568)
                     /gene="pcp"
                     /locus_tag="VUZ44_001048"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU0319980.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(40675..41034)
                     /locus_tag="VUZ44_001049"
     CDS             complement(40675..41034)
                     /locus_tag="VUZ44_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU0319981.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            complement(41045..41470)
                     /locus_tag="VUZ44_001050"
     CDS             complement(41045..41470)
                     /locus_tag="VUZ44_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU0319982.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(41793..42905)
                     /locus_tag="VUZ44_001051"
     CDS             complement(41793..42905)
                     /locus_tag="VUZ44_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU0319983.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(43071..43691)
                     /locus_tag="VUZ44_001052"
     CDS             complement(43071..43691)
                     /locus_tag="VUZ44_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU0319984.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(43695..44975)
                     /locus_tag="VUZ44_001053"
     CDS             complement(43695..44975)
                     /locus_tag="VUZ44_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU0319985.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(45036..46520)
                     /locus_tag="VUZ44_001054"
     CDS             complement(45036..46520)
                     /locus_tag="VUZ44_001054"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU0319986.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(46596..47873)
                     /locus_tag="VUZ44_001055"
     CDS             complement(46596..47873)
                     /locus_tag="VUZ44_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU0319987.1"
                     /translation="MSCSIDLLKHRYLKNIKENSELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(47980..48063)
                     /locus_tag="VUZ44_001056"
     tRNA            complement(47980..48063)
                     /locus_tag="VUZ44_001056"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48027..48029),aa:Leu,seq:caa)
     gene            complement(48073..48144)
                     /locus_tag="VUZ44_001057"
     tRNA            complement(48073..48144)
                     /locus_tag="VUZ44_001057"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48110..48112),aa:Gln,seq:ttg)
     gene            complement(48158..48230)
                     /locus_tag="VUZ44_001058"
     tRNA            complement(48158..48230)
                     /locus_tag="VUZ44_001058"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48195..48197),aa:His,seq:gtg)
     gene            complement(48245..48315)
                     /locus_tag="VUZ44_001059"
     tRNA            complement(48245..48315)
                     /locus_tag="VUZ44_001059"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48281..48283),aa:Trp,seq:cca)
     gene            complement(48320..48400)
                     /locus_tag="VUZ44_001060"
     tRNA            complement(48320..48400)
                     /locus_tag="VUZ44_001060"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48364..48366),aa:Tyr,seq:gta)
     gene            complement(48413..48485)
                     /locus_tag="VUZ44_001061"
     tRNA            complement(48413..48485)
                     /locus_tag="VUZ44_001061"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48450..48452),aa:Phe,seq:gaa)
     gene            complement(48489..48562)
                     /locus_tag="VUZ44_001062"
     tRNA            complement(48489..48562)
                     /locus_tag="VUZ44_001062"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48526..48528),aa:Met,seq:cat)
     gene            complement(48573..48662)
                     /locus_tag="VUZ44_001063"
     tRNA            complement(48573..48662)
                     /locus_tag="VUZ44_001063"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48624..48626),aa:Ser,seq:tga)
     gene            complement(48745..48818)
                     /locus_tag="VUZ44_001064"
     tRNA            complement(48745..48818)
                     /locus_tag="VUZ44_001064"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48782..48784),aa:Ile,seq:gat)
     gene            complement(48853..48923)
                     /locus_tag="VUZ44_001065"
     tRNA            complement(48853..48923)
                     /locus_tag="VUZ44_001065"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48889..48891),aa:Gly,seq:tcc)
BASE COUNT        14565 a        10700 c         8718 g        14944 t
ORIGIN      
        1 tcaaataagc atctggattg tcagtaagat agtttttaag tctatctcta tcaacttttc
       61 ttggttttgt tccttttact tggtggttta gctctcctgt tttctctttt agctttaacc
      121 agccataaat ggtattacgt gagatttgga aaacgtgtta tgcttctgtt acactacctg
      181 tttgctcaca ataagagaga acttttttac gaaaatctat tgaatatgcc ataaaaagat
      241 tataccacat tgtgtactat ttttggttca ttttactata tttgaagagg cgtttaaact
      301 atctgacata aaactcgttc tagaggaaaa acatccttta aaaagttagt ttattttaca
      361 acttagacat caaggtaggt taaccccttc atggaaaaat caagactctt agcactatgg
      421 gttaaactac cactggagac gtaatcaatc gctaaaccac gaaaacggct aatagtggtc
      481 atatcaatat ttccagaaca ttcaatccga gaacgtcctg caattagggt aatagcctgt
      541 tcaatctgtt ccaatgacat attatccaac atgataatat cagcacccgc cgccgcagct
      601 tcttcggcag cagcaaggct ttccacttcc acctcgacca ttttcacaaa aggggcatag
      661 gcacgcgctt gagcaattgc cttttgaaca ctacctactg ccgcaatgtg attgtctttt
      721 agcatgatag catctgataa attaaagcga tgattatagc caccgccaac tctcacggca
      781 tatttctcaa aaagacgtaa attaggagta gtttttcgag tatcaaatac cttaatgcaa
      841 tcatcgccta aggcttctac ataagcagct gtcatcgaag caatccctga taaatgttgt
      901 aaaaaattca aggcaacgcg ttcacatgtt aagagacttc tcaccgagcc tatgatttct
      961 aaaaccaaat cgccactagt caaacgatcc ccatccttaa attgatgagg attctggaag
     1021 gtcacctcgg catcaaatag ggtaaaaacc ctttgaaaaa cggttaatcc cgctaaaaca
     1081 ccagcttcct tggcaaaaag cgacaccttg gcttggccat gatgatcaaa aatggcattg
     1141 gtactgtaat cttcggaatg aacatcttct cgcaaggctg ctttcaatgt atcatctatt
     1201 tgaaaagggg ttaaatcagt tgaaatgatt gacatcacta agtcctctat ttttaatatc
     1261 acttgtaagc actagaggca attactatta acttccatag gaaatcacaa gcctgaatac
     1321 ctcattttta attctaacaa gtgtcaatac aattgtcaag acaattgtat ttttttgtgt
     1381 ataatagtca agtaccaata ggaaacaggt ggtcttttga gcgccaaaat tgccaatcta
     1441 tttccatatt ctaactgaaa ggacaattca atgattcatt taataatgat tagcgccatt
     1501 gctctagcca ttggaattgg ttaccgcacc aaaatcaata ttggcctgct ggctattgct
     1561 ttttcttacc tcatcgcaac cactctcatg ggattaagcc ccaaagaact tcttcatttt
     1621 tggccaacct cactcttttt taccattttt agcgtctctc tcttttataa cgttgcaaca
     1681 actaacggta ctcttgatgt tttggctcaa cacattctct accgcacacg cacccaccct
     1741 aacgccctct acatgatttt atacctgatg gcaacccttt tgtctgcttt aggtgctgga
     1801 tttttcacta ctatggccgt ttgctgtcct ctagcgatta ccctctgtca aaaagcggac
     1861 aaacaccctt tgattggagc tcaagccgtc aattggggag cttcaggagg ggctaatttg
     1921 ataaccagta gctcaggcat tgtctttcaa ggcctgttta agcaaatggg atgggaagag
     1981 caagcttttt cacttggcaa tcatatcttt atcgtcagca ttatctaccc actcatcgtc
     2041 ttgcttttat tatcctgtta cagccactat agtaagggaa gaacaaactc atccttgact
     2101 attgaccaac caccactcct cagcaaggtt caaagacaaa ccaccttgct catgatcagc
     2161 agcatggttt tggtttggct ttttcccttg ttgcatctca ttttcccaaa catcgcctgg
     2221 atagctactt atcaaaaaac atttgatatt ggctttgtct caatactcat ggtctgcctc
     2281 gccttaaggc tcaaattagg gaagcaagaa gccattttag ctaaggttcc ctgggctaca
     2341 attatcatgc tctgcggcat gagcttacta atgtctctag cggtcaagtc aggtttagtc
     2401 acactgatag ggcacctcat gacaacaacc attcctcatt tctggttacc tctgttcttt
     2461 tgtgtgatag ccggagtgat gtcactcttt agttccaccc tatccgttgt agctccagcc
     2521 ctctttccca tcattgctat catcagtgct caaaatcctc agattgatat tcacttactc
     2581 acaacagcca ccgttattgg cgctctatct actaatatct cacccttttc atcagctggt
     2641 tctctcattc aactctcact tcccaatata gaggaacgtg gccttgcctt caaaaagcaa
     2701 attattctgg gtgtccccat cagcttaagt ttgggactct tgaccacctg gattctcatc
     2761 cttctagctt ccttaagtta gatttattat ctaacttaag ggtggacttg gtataataaa
     2821 gtagacacaa aattaagtgg aaacgaggaa aagtcattat gccaagaaaa acctttgata
     2881 aagccttcaa actctctgct gtaaatctca tcctgtaaaa atgattagtt caactttaaa
     2941 aattcatccc aatagtcttt atcgatggat tcaagaatat gaaaaatatg aagaaagtgc
     3001 gttcccagga catgggagcg cacttcgtca tactcaattt gagatatagt gaaatgaaat
     3061 aagaacagga caaatagatc aggatagtca aatcgatttc taacaatatt ttagaagtag
     3121 atgtgtacta ttctagtttc aatctactat agtaaagttg actttcctgt accattttta
     3181 ccagtaatta atgtcacgcc tgaactcgaa gtatcaaaag aaatattatc aaacaatata
     3241 cgatgatcca ccctatacga aatattttct actttcattt tttctccttt tgaactaata
     3301 gcaaaagaaa cagttctgtt ttcatactct ttccccttca tctatattat tcgtaatgaa
     3361 aaataaaaaa ataaaatttt tttaaatgat tatgattcag aatttattca atatattaaa
     3421 acaatatttg aacaaataaa ttgggagatt gaaattcatt tctagcaatt tgttagaagt
     3481 cacagtctac tattctaacc tcagtatact atatgtgtta caagaaaaga ctcaaaaact
     3541 tctcgtcagt gtaagaatat ttgaaacact atttaaaact aaataactat aagaagtaga
     3601 tcaggtgaac aatttcagta cctactctat aagctatacg aagatatttt tcaacatgat
     3661 ggataaaacg atcactcttt taaagccatc ttatttagaa aagagaaacc atttaagcat
     3721 agatgggacc ttcttgccct gttttaaatt tttcttaaac tagagtctgt aaaagattgg
     3781 cttcattttc acattttctc ctaggaggaa tgtcgtaatg caaaagaatt aaattcaaat
     3841 aaatcatagc gatgacgact aatcgagtac tcaaacggag ttccgttatc caaataagcc
     3901 acttgttcta cttcaaatac cggttccgtt ggaaggagct gcaagtaatg ttgctcattt
     3961 tctgaactag aagaagctcg taagattttt gtagcactgg caatatgcaa tcctaacttt
     4021 ccttcaatgt aattgtaaat cgatttttgt aaaatatctt cagtaatacc tggaataaca
     4081 tcggtactca tataagtttg ttccagaaca taaggtttac cgtcaataat acgcaggcgg
     4141 taaatattat aaactggact ctgcaaagcg acctgtagtt tttctgctaa aaattcattt
     4201 gcaaattcta atttgaagtg aataatcctc gagtcaattg tagaatgagc atcttcagat
     4261 atttttgtca gtccccggat atctctttct ggaacgatta attttctttt tgagctgcca
     4321 cgagagagaa caaaggttcc ctgcccacgt tttctaaaaa ttaagccctc agaaactaac
     4381 aagtctaaag cttttttgat cgtcattcga ctacaggcaa actgtttagc taatgtcatt
     4441 tcatcaggta attgttcgtt catggtatat ttattacaaa gaatcttttc acgaatctca
     4501 ttgtaaataa ataaatattt tgtactcatt taatctggtt ctctctataa tattctaata
     4561 gtagtataac aaagttcaag aaatgaggca aacacaagat atgtatcaac aatttttaaa
     4621 aatgtctaga caaattttaa aattatgcta tactttatgt atagaataat agaaaggagg
     4681 ttgagcatga aaaaaaagtt agtatttcct aatctgtttt ggtggggagc agcttctagc
     4741 ggacctcaga cagaaggtca atatggaaaa gtacatgaaa atgtgatgga ctactggttc
     4801 aaaacgcatc cagaagattt tttcgataat gtcggacctc ttgtagccag taactttttt
     4861 catacttaca ccgaagattt ccacttgatg aaggaaattg gagttaattc tttccgcact
     4921 tccatccaat ggagtcgact catcaagaat ttagagacag gtgagcctga tccaaaaggt
     4981 attgctttct acaatgccat cattgaagaa gctaaaaaga accagatgga tcttgtgatg
     5041 aatttacatc attttgattt accagtggaa cttcttcaaa aatacggtgg ttgggaaagc
     5101 aaacatgtag tggagttatt cgtgaagttt gccaagactg ctttcacatg ctttggagat
     5161 aaggttcatt actggacaac tttcaatgag ccaatggtca ttccagaagc aggatactta
     5221 tatgctttcc attatccaaa tctaaaagga aagggaaaag aggccgtaca agtcatctat
     5281 aatctaaacc ttgctagtgc aaaagtgatt caactatatc gctcattaga acttgatgga
     5341 aagattggga ttattttaaa cttgacacct gcttatccaa gaagtaattc tccagaagac
     5401 ttagaagcaa gtcgatttac agatgacttc tttaacaaag tcttcttgaa tccagctgtt
     5461 aaaggaactt tcccagaaag attggtaaaa cagctagaga gagatggcgt gttatggagt
     5521 cataccgaaa aagagcttca actgatgaaa tcaaatacgg ttgattttct tggagtaaac
     5581 tactaccatc caaaacgtgt tcaagcacaa gcaaatcctg aggaatatca gacgccctgg
     5641 atgccagacc aatacttcaa agagtatgaa tggccggagc gtcgcatgaa tccatatcgt
     5701 ggttgggaaa tttttccgaa atccatttat gatattgcta tgattgtgaa ggaagaatat
     5761 ggtaatatcc catggtttat cagtgaaaac ggaatgggtg ttgaaaacga agcacggttt
     5821 atcgatgaaa atggagttat cgatgacgtg tatcgtattg aattttatga agaacattta
     5881 agatggctac ataaagccat tgaagaggga agtcactgtt ttggatacca cgcttggacc
     5941 gcatttgatt gctggtcttg gaataatgca tataagaatc gttacggatt tatctccgtt
     6001 gatttagaaa cgcaaaagag aaccatcaag agctcaggaa gatggtatcg caaagtaagt
     6061 gacaataacg gttttgaagt agaaattgag gagtaaagag aggagatatt catatgaaaa
     6121 actcaaaatt tatagaccaa tttgccacct ttgctggtaa actagggaac caaattcatt
     6181 taaaaaccct aagagatgca ttcgtaacag taatgccatt atatattttg gcaggtttaa
     6241 tcgttctttt gaacaacacg gtatttaagt ggattttcca aggggataca ttaacaagat
     6301 tccaatattg gggaataaca attgcaaacg gtactttaag tatttcaggt atgattattg
     6361 ctgtaatggt tggttatttc ttagctaaaa acagagattt cgaaaacccg ttagcagcat
     6421 caatgctatc attagtttct ttaattgtga tgatgccaaa tacagtttct gtagttcctg
     6481 acggagcaaa agatgctgta aacatttcag gtgttctttc attcaacaac acaggtacag
     6541 gcgcaatgtt cgccggggtt atcgtagcga ttattgcaac agaattattc attgaattat
     6601 caaatgttaa agctttacaa atgaaccttg gtgaaaatat tccaccagct gttagtagat
     6661 catttagcgt attacttcca gtcatgaccg tcatctcctt atttggggtt gtttcagcat
     6721 tattattcaa tataactgga atgaacttaa tctcaatcat tacaatcttt attcaagaac
     6781 caattcgtca tattggtaca agcttaatcg gggtcattat tatttactct ttaggaaata
     6841 tgttatggct atttggtatt caccaagcag ttatttacag tgccatccta gaaccattac
     6901 tattaattaa cattactgaa aacatcactg cagcaaataa tggacaagcc attccacaca
     6961 tcatcaacct atcacaaata caaacattcg ctttaatggg tggtagtgga tctacattat
     7021 gtttattaat agcaacattc ttagtgagtc gcaatgctgt ctctaaaaac gtggctaaat
     7081 tatcttttgg acctggtatc ttcaatatca atgaaccagt attattcggt tacccaatcg
     7141 tttataacat ttcattagct attccattta tcacagttcc agtccttggt attttaatca
     7201 gctacttagc aacagttaca ggattcatga gtcctgcatt tatacaagtt ccttggacta
     7261 caccagtatt cttaaatgca tggttagcaa cagcagggga cgtgagagca gttctagttc
     7321 aattcatcat ctttgcactt ggagttcttc tatacattcc atttatcaaa gttaatgaca
     7381 aagttgttga acaagaaatg gaaggttaag attatgaaac aaattttatt agtatgtaat
     7441 gcgggaatgt cgacaagtat gcttgttaaa aaaatgcaac aaagtgcgac tgaacgtggg
     7501 attgaaatct ctatccaagc aaaatcaatg acagaagcta aaaagaatat ccatgaagca
     7561 gatgtcattc taattgggcc acaaattcgt tatgagttac ttgctgtgaa agaaattgca
     7621 ggaaatatcc ctgtagatac cattgatatg cgggattacg gaatgatgaa tggagcaaaa
     7681 gttctggaac aagcacttgc atggatagga gaaataagat gacagaagaa atggaatata
     7741 tctgttttca gctcattgcc aatagtggag cagccaaatc atcctttatt gaagccatcc
     7801 aactagctaa ggcaggaaat ttaaaagaag cgaaaattaa agttgaagaa gcggaagact
     7861 ccttagtaga agcgcacaag attcactcta atctcataca aaaagaagct actggagaaa
     7921 aaataggatt ctccttgcta tttatgcatg cagaagacca aatggcttca acagagatta
     7981 ttcagttgct atctaaagaa ttcatcgatc tctatcaaaa taaataggaa cactgtcatt
     8041 cccatctgtc tttattaatg acgactacat tgtaggaacc tccaaaagtt ggacaaaatg
     8101 attgaaagga ttggatcctg cattacacaa gatccaatcc ttttctttta ctctagtttt
     8161 tataatatgt tgaatctaga atagtccact gtagtttcta aaaaattgct ggaaatggat
     8221 gttaagctcc aatttatttg tttatatctt atttcagttt actatactag cttattattc
     8281 tagtgaaaaa ttgaatgagc cactatttat ttaatatgta tgatgaggga atgactcaaa
     8341 aacttcttgt cgatataaga atatctgaga tagtatttta aaacgaaagg attataaaag
     8401 ctcatttcct tcgcacttat tttatagaga tctatcatta tactctttag aaatcaaaaa
     8461 gcaacacacc ttgtcatcgt tttctcgttt gctctttgat tttaattggg ccttagtaaa
     8521 tactactctt aaattaaact atagtgaatt gaaataagat gtgaacaact ctatcagaaa
     8581 agtaaaatta atttctataa atgttttagc aattgtttcg tactatttta gattcagtct
     8641 actatactat attttttata tattaaaatg aaataagaac aggacaaatc gatcaggaca
     8701 gtcaaatcga attctaacaa tgttttagaa gcagatgtgt actattctag tttcaatcta
     8761 ttatatattt tgtttctatt ctagtttttc aaaaagggca aaaaggcctc aatatcataa
     8821 aaaggcatcc tatcaggtgt tcaaaaacct tgataggatg ccttttatca tagaaaaatt
     8881 actggatctt tccctcaaat tgagtttttg tcttgcttct agactaataa acaattattt
     8941 acggcgtcct ggtctttctt tgtagccata gtatgcatct tcgatgattt cttgcatatg
     9001 gtctaccatt ggaagacgtg ggttagctgg tgaacattgg tcttcataag ccaggaaggc
     9061 taattcacga gaatgttctt tccattcttt ttcgtcaatt ccttggtctc taaaattcat
     9121 ttggatccca atacgttcac cgagttcgta gacagctttt gcgtaagatt caaccccttc
     9181 ttctggagta gaagctggaa gtccaagcat gcgtgcgata tcttggtatt tttcatctgc
     9241 acggtagtag ttgtacttag gccatgttgc tgtcttagct ggacgtgtac cgttgtaacg
     9301 gataacgtat ggaagcaaga tagcatttgt acgaccgtgt attgtgtgga attgcgcacc
     9361 aatcttatgg gccattgagt gagaaatacc taggaaggca ttggcaaagg ccataccagc
     9421 gattgttgaa gcgttatgca ttttctcacg tgagtggaag tctgcattct taactgagct
     9481 ttcgagattt tcaaagacca atttaatggc ttgaagtgct aaaccatcag tgtagtcact
     9541 agccatttgt gatacgtatg cttctgtcgc gtgagtcaat acgtccatac cagtatcagc
     9601 agcaacaaat cctggaactg tcaataccaa agcaggatct acgattgcca cagttggtgt
     9661 caatgagtag tcagcgattg ggtatttacg gttgtttgct ttatcagaga taacggcaaa
     9721 tggtgttact tcagatcctg taccagatgt agttggaatc gcgatgaatt tagtcttctt
     9781 accaagcaat gggaacttga aggcacgttt acggatatcc atgaattttt ggacaaggtc
     9841 acggaagtcc acttctggtt gctcgtagaa gagccacatt actttggcag catccattgg
     9901 agacccacca ccgagtgcga tgatggtatc tggtttgaag gcacgcataa tctcagtacc
     9961 acggtttaca gttgtgatat ctggatccgg ttctacatcc gcaaagattt ggtaaacaac
    10021 cttattgcga cgaaggtcca gttgttcgat gatacgatca aggaaaccaa gctctaccat
    10081 ggcatggtca gtaacgatca tgacacgttc aacgtcacga catttttgaa ggtattgaat
    10141 tgaatcacgt tcaaagtatg tttttgaagg aagtttcatc cattgcatgt tatttctccg
    10201 tcttccgact tttttgatat tcaagaggtt aatggcacta acgttatccc caactgagtt
    10261 gcgtccgtaa gaaccacatc caagtgtcaa tgatggcaag aaggcattgt aaacgtcccc
    10321 gataccacca aaagtagaag gtgagttaca gataacacga atagctttaa cagctttacc
    10381 aaattcttta gtcaattctt cgtcagctgt gtggatagct gctgagtgtc caagaccgtt
    10441 aaattcaacc atttgacgag ccttagtaat accatcttca cggctttcag atttcaaaac
    10501 tgcaataact ggtgacaatt tttcacgagt caatggctca ttttcgccaa cttctttaca
    10561 ttctgcagca agaatgtttg ttccttctgg aactgtaaat cctgcttgtt ctgcaatcca
    10621 agttgctggt ttaccaacga tgtcagcgtt caattttgca ccagcacagt ttttgctgtt
    10681 tgctttgacg ccgaagcaga actcttcaag aagagctttt tcttttttgt ttacaaagta
    10741 agtgtggtaa gatttgaact ctgctacaaa ttcatcgtaa atttctttat caatgataac
    10801 tgcttgttca gatgcacaga ccataccgtt atcaaatgat ttagacatga cgatatcgtg
    10861 tgctgcttga cgaatgtttg ctgatttttc aacataagct ggaacgtttc cggcacctac
    10921 cccaagagct ggtttaccac atgaataagc cgccttaacc atggcattac cacctgttgc
    10981 aaggattgtc gcaacacctt cgtggttcat aagggcactt gttgcttcca tagatggttg
    11041 agtaatccat tgcacacagt tttcaggagc accagctgcg atagctgcat cgcggacgat
    11101 acgagctgca tgagcagatg attcttgtgc tgatggatgg aaggcaaaga cgattgggtt
    11161 acgtgtcttc aatgaaatca atgatttgaa gattgctgtt gatgttgggt ttgttgttgg
    11221 agtaatacca caaacaacac caactggttc agcaataaga gtcaatcctg ttacatcgtc
    11281 ttcttcgata acaccaactg tcttagtgtg gcgcatgttg tttactacgt gttcacaagc
    11341 aaacaagttc ttagttgctt tatcttcaaa tacaccacgt cctgtttctt caaaggcatg
    11401 taaagccaat tctccatggg catccaaagc tgctactgat gctttggcaa cgatgtagtc
    11461 aacttgctct tgattcaatt tacgcatttc ttcaagggca actagagctt tttgaaccaa
    11521 ctcatctacg tgcttttcag caacgagttt cttttcctct ggtgtcacag tttttttatc
    11581 agccatattt tcctccatag ctttcaagga acgatatcct ttgttaattt tttcacaagt
    11641 ttattataac gcattatttc aactttgtaa acagtttcat aaacatttca caaagaattt
    11701 ttaaactctt gtgaaacttt tctcattttc ttttcttatc aagttttatc tttgaagttt
    11761 gtgaaattta tttcaaatat tttttatttc acaaacttgc ttggaagagg gatttggaaa
    11821 gaaagggatt tacaggtaag cgcttacctt gtgattctaa taatacctcc tttgataagg
    11881 aggctttatt tttgttgaaa aacgccttgt ttaaaagttc cttcataaac gacttcttgt
    11941 tctgttgtta gtttcccttt tccttcagcc tgaccattta caaaatcacc ttcgtaggtc
    12001 cagccttctt tagattgaaa ggtacctttt ccgttgaagg ctccattgtt gaagccacct
    12061 gtatattggt ctccattttg gaaggtaatg gtaccttggc cattcatttt accacggaca
    12121 agactgccat cataaacaat cgttccatta tcgagtttta agacaccttt tcctggaata
    12181 tttagaaaaa agacgagtac agcacagaaa acaatggtaa ctactgccaa aagctctaaa
    12241 cgtggacgag tcagatagac acgatacttt tcgtaaaaat tcgtaagatt ttccacctta
    12301 actctccttt tctaaacgtt ctaaccaagc ttgacagccc tcttgaacac gtcgataggt
    12361 ttcttcaaaa tctcctgtat accaagggtc tggaacactt tcagatgaaa atgagtaaat
    12421 cttatcttga cagtctactg gacacatctg acgtaagtca gaaatatttg aagcgtccat
    12481 tccgataata taatcaaagg cttcaaaatc ttccttacta atctgaagcg atgtcttgtt
    12541 cttgtcataa ggaatctcat actcttgaaa aattccctga gtccccttat gaatcggatt
    12601 gccatgttcc caagaggaag ttgctcgact ttggatttcg tagttatctg tcattgattt
    12661 cataacaaac tcggccatag ggctacggca aatatttccc agacagacaa agactaattt
    12721 tttcatccca tttcctttct tttatagaaa acgggagttc gtgatcccgt cttatttttc
    12781 aattgcgcct tctagtgaag ctgtttcttt cagcggtaat actgtcttga tagcagctag
    12841 ttcaaaagtc aagtaaactc catctacgtc aagaactatt gttcccttct ccgtatctac
    12901 ttcatcgact gttccataaa gtccaccgat tgtaatcact tcatagcctt tttgtagttt
    12961 atttaagctt tccatacgct tttgagcttg tttcttttga gaacgttgca taaagaacat
    13021 caaggccatc atacctacaa gcatgattaa aaaagtaata tttggattca ttgttttctc
    13081 ctttgtcttt tacataggac tactatatca aatttcagct acttttacaa gattgtacct
    13141 tacttttctg gtaagaaaaa ccagagctta cgccctgatt tttaggatta tttcaaattt
    13201 cgaacaactt ttacaagatt ttcgacagta aagccatatt ctgccaatac ttttggtgct
    13261 ggggcagagg ctccgaaggt atcaatacct agaacggcac catcgagacc aacatatttg
    13321 taccagtttt gacttgcacc catttcgact gcaacacgac ggcggactgc atttggaaga
    13381 atttcttcct tgtaagctgc atcttgttta tcaaagacat ctgtagatgg catgctgact
    13441 acgcggatgt tttcgccttg actagccaat tctttagcag ctgagacagc aagattaacc
    13501 tctgaacctg tcgcaatcaa gatggtatca aagtcggctg cattttcata tacaacataa
    13561 gcacctttag caaccttgtc gaagtctgtt ccctcttcga cagtcaagtt ttgacgtgtc
    13621 aagacaaggg cagttggtgt tttctcactt gtcactgcaa ggtaccaagc tgcttgcgtt
    13681 tcacgcgcat ctgctggacg gaaaacattt agatttggca tagcacgaag acctgctaaa
    13741 tgctcaactg gttcgtgagt cggaccatct tccccaactg cgattgaatc atgggtaaag
    13801 acataagtca caggaagtcc ttgtaaggct gacaagcgga cagctgcctt cacatagtca
    13861 gagaagacga agaaagttcc accgtataca cgaagtccac catgaagggc catcccgttc
    13921 aagattgttc ccattgcaaa ttcacgaaca ccaaactgaa tgttacgatt caagcgattg
    13981 gcatcgtctt gaagtccatc cgtcttgata taagtcatgt ttgagtgagc aaggtcagct
    14041 gatccaccta gaaaggttgg taatttagct gccacaacat tcaaggcatc ttgacttgaa
    14101 ttacgagttg cttgagaaaa accattttct aaagctggga agtctgctgg agtcacttcg
    14161 actggatcac gtccgtcgat gatggcttct acttctgcag ccagttctgg atgagcttct
    14221 ttataatctg caactaattt agtccaagct tgataagctg atgcgccacg gtctgcaaca
    14281 tgttctttga aatcagcata tacttgttct ggaatttcaa atggttcgta gtcccaaccg
    14341 agggcttgac gagttgatgc agtttcatct gctccaagag gggcgccgtg tacagcatta
    14401 gttccttgtt tgtttggaga accgtatcca ataaccgtct tcacttcaat caaagatggc
    14461 ttgcctgaag cttttgctgt ttcgatagca gcatggatgg cttccaagtc tgttccattt
    14521 tcaaccaagg cagtatgcca accgtaggca ttgtaacggt cacgaacact ttctgtaaag
    14581 gaatcctttg tctcaccatc caagttgata tcatttgaat cataaagaac aaccaactta
    14641 tcaagttttt gcaaacctgc gtatgaagct gcctcgcttg agacaccttc catcaagtct
    14701 ccgtctccac agataacgta agtatagtgg tcaaagatat tgtagccttc acggttatat
    14761 ttggctgcca agaaacgttc tgcttgggca aaaccagtag cagttgaaat accttgccct
    14821 agaggacctg tcgtagcatc aatccctgcc gtatgaccaa attctgggtg acctggtgtt
    14881 tttgaacccc attgacggaa actcttaatc tcatccatgc tgacatcttc aaaaccagaa
    14941 aggtgaagaa gagcataaag gagcattgaa ccatgacctg ctgaaagaat aaagcggtcg
    15001 cggttaatcc agtttggttg agctggattg atatgaagtt gttttgtaaa gaggctgtaa
    15061 gccatcggag ccgctcccat aaccacacct ggatgacctg agttggcttt attaatggcg
    15121 tcaataccta gaaaacgaat tgcattaaca gatagatttg acatagaatt tcctttctat
    15181 ttgaggtgat tattgaatca cacattctat tttactatta tatgaaaatt atccgtatca
    15241 tgcaacatac ggataacctc caaagaatat ttttatatta tagcaaagct ttaaattgaa
    15301 tgttagagtc ttgttcaaaa caatcatcaa aaccacgtgg atgatggtat tctactaagt
    15361 gttgatcttg aggataagtg tacttaccgc caacttccca gataaatgga tggaaatcgt
    15421 attgcaagcg atcttttcgc attttccaaa gttctagaat ctcattagta gaagccatga
    15481 agttagacca gatatcatag tgaactggga taatgacttt ggtacgcaga ttttctgcca
    15541 tacgaagaag gtcgatagat gtcattttgt cttggatacc taccggattt tcaccatagt
    15601 tattcaaagc aacatcaatt ttaaagtctt taccatgttt tgcaaaatag tttgagaagt
    15661 gagaatctgc accatgatag atggttccac ctggtgtttc aaagatatag ttaacagcct
    15721 tttgagccat ttcttcatct gtaacagcca agccagcaag ttcaccgcct gtctcatcag
    15781 caccgttcac tgggagagtt accaagcaag tacggtcaaa tgattctact gcatgaatct
    15841 tcatatcttt taattcgata gtgtcacctg gtttaacaac gatgatacgt tcttttggaa
    15901 caccccatcc ttcccagatt cgtccacagt ggtaaggacc gataaactta acatgctcta
    15961 acttaggatt gttgagaatt gctgcagctg tgtatgggtc gatatgatca ctgtggaagt
    16021 gtgaaactaa gtaatagtct agttcgttga tagcaaatgg atcgataacc attggctgaa
    16081 cacgcaagtt tggttgcaac ttacgaacac ctgccatatt tgccatttgg tgcccacgaa
    16141 ccatatcttt cacttttttg gttgattttc cacggtttga ccaaaggtcc atgacaacgt
    16201 tagcaccagc tggtgtctta atccaagtac cacagttgcc tagccaccac atggcaaagt
    16261 tgccttcagg tacgacttct tcttcgattt cttcgttcaa ccatgttccc cactctggga
    16321 aagtggctaa aatccatgac tctcttgtaa tttctttgac gtttggcata tgttgcctcc
    16381 tttggatata attgttatct ttgagattag tataccaccc ttcaaaacac taaaaaagac
    16441 caagaaaaac acaggtttgt gttcatcatt ggactgtcct tcaaatatct tccaaaaaag
    16501 cttgaactac tatttcttga tttataagtg tttgaacctc ttcttggaac ttactagcca
    16561 acttgctgtc tacaatataa gacgaaataa gactagaaag attttcactg aaacttttgc
    16621 tcttattacg aaatatattg tgtttaagat agtctagcat tttcaaaata tcttctgctt
    16681 caaggatagg attaaccctt aaaatcggaa atctgctatc caaatcatca ttagtagtaa
    16741 tcactacatc aacttgtgca atatcttcca cactcttaaa ttgttctgtt gtaaatacag
    16801 tgtcaatttg ctcatttgga aaataaagtt tgcattgttt cagcaaaagt ctcgaaaccg
    16861 caacaccttc atcacaaacg agataaactt ttttcatatt tttttgagac gatggtgtat
    16921 attttaaaaa tcctccaata tgaatcgtca aataggcaat atcatcgtct gttagccgaa
    16981 taaaccatgc tccttctaaa atttccgcag attttctagt gactaaaaat aattctccat
    17041 acttggatcg aatttgtttt gttagaggat ttttagaaaa aataccgtaa gtctttctaa
    17101 ataacaaggc tttacagtgg atcatcaaat ttcgtaacaa atcatccttg ttctcaatct
    17161 ccattcggat ttgtgattca aaataccaga taaattcttc taaagcaagt tttaattgcc
    17221 gaaaatcatc actttctgca tgaatatcca aatctttacg ataggagagg aggagaacag
    17281 ctacaagaga aacttcaagt cctgacaaag aaatttcaaa cttttgaaac aaccgttctc
    17341 ctaatttctt agacacctga tactctattc tttttcttat caaagaaaat tctttctcta
    17401 tatcctgatg tctttcttga tactgttcaa cattatgaca gcttaacagc aaataaggta
    17461 gaacctgcaa cataaaagtt atttcatgat ggtttatttt cttccctaaa tcttgttcaa
    17521 ctaaaggaac ctgttcctta aaaaattggt tcatttcaac agaaagcaaa cactcatcat
    17581 ctaacctctc tttcatctta tcttctaaaa tagatacaaa agtggcattt tcttccataa
    17641 aaatatgata tagaagcgat tgaagatact gaattttatt aagagggtgg gcatgaaggt
    17701 ggtatccctg tgacttgctc acttgcaaga tcacctgata ttgttccaaa gttagttgat
    17761 aacgaatact attcaaatca ttgagaacag tattcctaga tacctctgtt aactctatca
    17821 atttttcaat cgtaatacgt tctttagaaa tacctatcca tagtaacatt atcatcatac
    17881 gttcatgcgc actcatgata taatcgtacg aatctacttc cgataatagt ttacaacaag
    17941 catctctctg ctcttccgtt aagtgaatac caattcgtgg aatactaatg atgtgaagcg
    18001 cctcgtcacc cagagcagca ttgattttgt caatgtgata ataaattttc cttcttgact
    18061 ctttcaaatc tttcgaaatc gccataatcg ttttggacgt ttcttgatcc atcaaatatt
    18121 gaagcaaatc acaacttgcc ttatccagta ccatattaaa aaatccccca aatctattga
    18181 tatcacagca attcttttta ttttaccata tatatatcaa gcgctatttc taaaaaatct
    18241 tttaaaatta cttcaattcc aactttactc tcaataaaaa tcaaatgtaa aaagaggagc
    18301 taaatttatc tttttctcct ccttcatcgt tcttactttt gaccataata agcatttggt
    18361 ccatgtttac gttggtagtg tttttctagt atgtactggg gagcaggtcc aactcttgga
    18421 ttgatttgtt ctgtaaagcg attcatcttt gatacttcct ctagtacgac agagtgataa
    18481 acagcattct ctggattttt gccccaggtg aatggaccgt gattgcgtac aacaattcct
    18541 ggtacttcaa ccgggttaag tccgcgatgt tcaaactctt ctacgataac caggccagta
    18601 tctttttcat aggccacttc tacttcgtcc ttggtcaaac tacgggcgca agggattgaa
    18661 ccgtagaaat aatctgcatg ggttgttccg tagaaaggaa tatcacgacc tgcctgagcc
    18721 caaccaacag cttctgtcga atgggtgtga accacactac caatttctga ccaagcctta
    18781 tataattgca catgagttgg gaggtcggaa gatggtctta aatccccttc taggatctta
    18841 ccatctagat cagtcactac catgttttca ggtgtcaatt cgtcataatc cacgcctgat
    18901 ggtttgataa caatgacacc gagttcgcga ttaacttcag atacattccc ccaggtaaat
    18961 ttgacaagtc catgttttgg caatgattga ttggcatcac agactcgttt acgcatagca
    19021 ttgattactt gattcatctt acatcaaacc tgctttctta atgagtggat agagaaaagc
    19081 ttgcgcctct tgaatggctg cgcgtgtttc ttctactgtt tcacaatttt cagaccacat
    19141 ttcgattagg aaaggtccat tataattggt ttcctttaaa atatcgaaag cttcttccca
    19201 tttgacacaa ccttgcccga aaggtacatc tcggaactgg ccctttgaac tttctgtcac
    19261 tgcataagta tccttgagat ggagagctgc gatggcatga tgaccaagat aaaactcact
    19321 atagatatca ttatgccatg cagacacatt accaatatct ggatatacaa agaggaaggg
    19381 agagtcaatc tctttttcta tagccaaata tttttcgatg ctactgatga aaggatcatc
    19441 cataatttca atagcaagta ccacctgagc ttcttcagcc cagtcacagg attttctcaa
    19501 atttttgata aaacgttggc gtgtctgggg tgacttttcc tcatagtaaa catcgtaacc
    19561 agctaattga atcgtacgaa ctcccaagtc ttgagctaat tcgatacatt ttttcatgag
    19621 ttctagagat ttttcctcta gaactgaatc ttttgatccc aatgggtagc gacgatggcc
    19681 tgaaaaacag atagaaggaa tacgaacacc agtttcatag atttctttga caacttccaa
    19741 gcgttcttcc ttactccagt caagtcttgc taaacgctcg tcacgttcgt caatagacat
    19801 ctcgataaaa tcaaagccta actccttggc aaaatttaaa cgttctagcc aagtaaagtg
    19861 tgttggggtt gccttttcat aaattccaat tggacgtacc atgatttacc cccaaattcg
    19921 tttgatttca tccttgaagg cacgcgctgc tcctgctgga tccacagcct ctgtaattcc
    19981 acgacctgcg ataaaggtaa agacatcaac accttcaaag agtttgagag tatctacatc
    20041 tagaccacct gttacagata cacggaagcc catgtcaatg agttttttaa ccttattaag
    20101 gtctttttca ccccaagttt caccagcaag aagagcatca cgagattggt gataaatagc
    20161 ttgtgagata cctgcatcta gccaaagctg agcttgttca aaagtccaat cgccataaag
    20221 ctcgatctgg atttcgcctc gttctcctcg ttcagtcttg atagccttta gagctgcttc
    20281 catagtaggg atggttgcac aacagataca agtcatccag tctgctccac gaaccgcatt
    20341 atttttagca actgttccac cagcatcagc acattttgtg tctgccacaa taatcttatc
    20401 tgggaaaagg ctacgcaaga cttcagccag ttcacttcca acttgaagca agcaaacagt
    20461 tccagcttcg ataatatcta cttcctgacc aacagaaaca gctgctttaa tcgctccttg
    20521 caagtctgaa tggtctaatg caacttgtaa attaggtatt ctttttgtca tttctttatt
    20581 cctctttcta actttccaaa tccaatcctt cgagataagg gctatcctta gattcttcaa
    20641 tcatagccaa gacatcttct ttagtctggc aagcctgtaa acgtgcaata gaatcttcta
    20701 attcaaacag ggcaataatt tgtggaatgg ctacacttgt gtgaattttt gaacttgttg
    20761 ctgctagtgc caacaaaaca gatacctctt tcccatctga aaatacaaca ggattttgta
    20821 aggtaattaa tgaaaaggca tcactttgca caccagcttc aggtctagcg tggggcatag
    20881 ccatacctgg catcaagata tagtaaggcc catactcttc agtcgattca atgatagcat
    20941 cgtaatactc tggcaaaatt gccccacttt caatcaaggg atctactgct accttgactg
    21001 cttctttcca atcgttagcc tctaaaccta gtcggatcga gtcgttgtca attaaagctt
    21061 gttttaaatt catatctgcc tcctttattt aaagaggggg ctggacagaa acgataactc
    21121 tcagtttctg tccagccccc tccaaccttt tactgtagtg cttgactgag tttttcggtg
    21181 atttctttat catccatcaa gttatcaagc ccaattaact tcccattagt tcgcccttcc
    21241 aattcttgaa tcaaatgaag agaagcgatt acaatgtcat atcctactgc taaaccttta
    21301 gcttcaccga cactgcatga attgactgta aaatctgttt gattaagctt acggagagca
    21361 ttttcaacct tcatcttgat aaccattgat gaacccattc catttccgca cgctgctaat
    21421 actttaacca ttttatttct ccttttctag atactaagct tcttcttgaa cttcaccgtt
    21481 gtaatatttc tctttatctt ttgctttggc aaattgaagt tgaggaataa caagccagaa
    21541 gagacacaca agtacataac caacaatacc aaggtatttg aagatatatc caaatccaag
    21601 ccatgggaat tcaaagtcga tatttccatg gtagccacca taagatgcca aatcgagaag
    21661 ggccacacaa agagctccta gagcaacttg aaggacacct gatataaagg aaaggataac
    21721 agccgctttc catccgccgc gtttatcagc gtagaccgca atggctgcat tgtcaaagaa
    21781 cactggtaca aatcctgtaa taataagaat cggattttta aagacgatga gcaaaacaat
    21841 tgtaatcaat tgaccaatca aaccaaaggt aaatcctgac aagacagcat ttggagaacc
    21901 aaatccataa gaagctgcaa cgtcaaccgc tgggaatgaa cctggcaaca atttgtttga
    21961 aataccttgg aaggcgtttg tcaactcaga tacgaacatt cggacacctt gcatcaaaac
    22021 gaacaagtaa actgagaagg taaaggctgt ttggataatg tacataaaga aatcttgttt
    22081 agcaggattg aatagagttc ctgaagtgat gacttcttta ttagacataa tgtctggacc
    22141 caagattaaa agaatggctc cgaagaatac gagcatcaag gtagcagatg caacaactgt
    22201 atcgtggaag attgagagga acttaggtaa tttaagattg tctaaacttt cttctttctt
    22261 accaaagcgt cctgctactt tatctacaaa ccagattgca aattgctgtt ggtgaccaat
    22321 cgcaaatccg ccaccaccag tcaagcgttg agttgcctca acagtcatat ttgaactaac
    22381 tgcccagtaa agtccacaga tgataccaat cgctgctgta ccgtaagcat tgcgcaattg
    22441 tggtactaag aatagaacca taagagatac tgttgcagct tgttgtacca tgatgtgacc
    22501 agtaataaag agggttctta ccttcgtaat ctttcgaaga gctacgagca agatatttat
    22561 tccaaaacca atcaatagag ctgtagttgc agttccaaca aaatctggaa actctgctac
    22621 aattttgttg tttgctgcag caagtccaaa ataagggtcg ataaccgctg caccaatttg
    22681 gaatttgtag ttaagagctg ctaagattgg acgaaaggtt gtaaccaaac caccagcacc
    22741 cacgttaagc aacatatacc ctactgttgc tttaacaaac cctgaaaaaa cgtcatgggc
    22801 aggttttttc aaaagtgcat atcctatcaa caccaataaa cctacgaaaa atgcgggatt
    22861 ctgcaaaata ttgctagaaa accaatttag aacacttgaa acgacttcca taattgttct
    22921 ccttttgaat tgtttttgta agtttattat ataatgcgaa agcgcaaaca aaaagaccaa
    22981 gaattacaca gcggactgtt cactcttgga ctgtatgatt tatgatgttt tacaaattat
    23041 cttattttct cgtagctaga taatagggaa gaattttaga ataagacttc aataagcctt
    23101 ctacgatttc ttcttcagac gaattttctg tcataggaac atctaccttc actaaaactt
    23161 ttcgaacttc ttgacttctc accttctcgc gtaaagtacg acgcttttct tcattcgcct
    23221 cccaccgttg actttgacca ttagagtagg ttagataata aatcccttta acggttggaa
    23281 tgtctaaaac tttggcctgc ttgcccagtg tttgctcatc cttcttacgt tcgatgaaac
    23341 tgacttccaa agaaattcca aagtcagtag atgtcccata caaacgtaag gccatcatag
    23401 gttctgtcac ttgtccgtct ctctgtagat aaacccaaaa atgtggtctc aaacgctggg
    23461 cctgattcat ccactgacta gtctgttgga gttgccattc tggatggctt gcttgaaagg
    23521 ctttggccag ttctgtaaaa gcctttcggg cctcttgtcc tttgtggcgg aacgccagca
    23581 tcttctctcg ctctgctccc gctttatcag gactacggta ctgcaaacca gaaaagtcta
    23641 gatagtctct tatcttattc aacatcagtt taacctcctc taactagcaa aaaatcaggt
    23701 caaccctgat tttacttatt ctgtatctac aacaacatag cgatttggct catcaccttc
    23761 agagtaacta gtcacgccat ccatacgtga aataatacga tggataatct tgcgttcgct
    23821 atttgacatt ggatctgttt tatgactgcg accttcttcc aaaacacgat tcgccaattt
    23881 ttgcgcatag gtctgcaaga cttctgcacg gtgttcgaca taatcattga cattgattgt
    23941 aacgtagaag gttttggaat agcggttgta aagataattt tgagccaaca gttgcaaggc
    24001 cttcaagact ttaccatggt agccgataat acgacctggt tcgttggtgt caatttgtag
    24061 attgatgcta cgacggttat aatcatttga aagtgtagct tcaacatcca tgtcatccac
    24121 aatcgcttga acataggcag tcacatccgt agccacctgg gcaatatcat aactttgctc
    24181 gaccttcaag cccatctctt tcaagtcttg attttcagtt tgatcttgct cagtttcaag
    24241 gtcatcagcg cctgcttctt ccctcatcgc ttcctcgatt tgaagttcat ttaaaatctc
    24301 aatgtgacca gtttcttcta agatagtgct ggcatgtctt tcatgtttta agatttcagc
    24361 cttgacttca tcagaaatac cttgaccttc ttcctctatt tttttaatag cattaaccac
    24421 atgaccaagg tcaacggttt cttcactaac cgtcttcaca ggctcgttca aatcattgat
    24481 ttttttcgga acgcctttta ctacctgttg atttgctttg acaacagtcg tttcactaat
    24541 cgcttcaata tccacttggg ctggtttttt accaaataga ccaagaaagc cttttttctc
    24601 cctagaaatg actttgatat gagccttcat tcttggaata tctaattctt tcaatccttt
    24661 ctggattgct tcttcaacag ttgaacctgt aaatactacc attaccagat tcctccttat
    24721 ttatttcgtt ttctgagcct ttttcttggc ttttcttttt ctattttcca aatctttttg
    24781 tgcctgtact acggcctcgc gctctgcgat aatcttgaat ggattattca agaaataggt
    24841 ttgcaagact tgataagcat tagacactgt ccagtatagg gcgactccac ctggcgcata
    24901 aactgcaaag ataaaaatca agactggaat cccatacatc atcgcagtcg tagcgccatt
    24961 tcgttcagac aaagctttgt tggacaacca agtacttaaa aaggtgaata ctgctgctaa
    25021 aatcggaaga acaagggttg tatccacact accaaggtta atccataaga aatgacctgt
    25081 ctttaaaaag tcaactcttg atagggcttg gaacagggcc aaaataaccg gcatctgaat
    25141 caaaatcggc caaagagagt ctgactgtct gacacccatt tctttaaata ctttacgcat
    25201 ttcctgctct agtttggttc tgctttccat atctcgacct ggatattgtt ctcgaagcgc
    25261 cttaatgcgt ggctgagctt cctgcatttt cctagaagcc accatttgca cctgaaagac
    25321 tggcaagagg actgtacgaa tcaagaccgt aaagagaata atccccactc cgatactaat
    25381 atcaaacgat aaaaagcgaa tgatttccgc aaagaagtaa accaatttac tccaaaaatc
    25441 agccgattcg gctgtaatat cgctagttac cccattagtc gcacaggctg tcatgattaa
    25501 cagagacagt cctagcaaac tagtcaactt tagtttcttt ttcactccca tttccttccc
    25561 ggtaaatctt tgataatttt aatacatgga gtagattttt ctccatctct gcgtatccca
    25621 aggtttcgac tccttttcga gcaatgacaa caaagtcgac atcttctacc agactccctt
    25681 ttgcattctg gataatatgc cgaatccgtc gcttaatttg atttctagtg acggcattcc
    25741 ccagtttttt gctaactgat agacctactc gaaaatggtt tttctggttt tctaattggt
    25801 agaccacaaa tttgcgatta gcaaaacttg tcccctcctt gaaaatcgcc ttaaaatctt
    25861 tctctctttt tacacgaaag tttttcttca aaactcaact ccatctatta aattactact
    25921 attataccat atttttcaaa aaagccaatc atagcaaggt tttggacaat ttcatcagaa
    25981 aaagaagctg gaaaaataac tttcccaact ccttgtattg aatatttttt tagtttcact
    26041 tattttttca agcgttcaac gtcacgggca atgactaatt cttcatctgt tggaataacc
    26101 aagacacgga ttttagctgc ctctgttgag atgtctcctg taacgccaaa gacattcttt
    26161 tcatcatcaa catcacaacc aaaccacgaa atccctgaga ttacatcacg acggaaactc
    26221 tctgcatttt caccgacacc tgctgtgaaa acaatggcat ctgctccatt tagcactgca
    26281 aggtactgac cgatatgttt ttggatacgg tcaacataca tttcataagc caagctagcc
    26341 tcgtgattcc cttctgctac agctgcttct atatcgcgca tatcgctaga attagcagaa
    26401 actcccaaaa gacctgattc acggttaaga acacgactga tatcttctgg tgtgttaaaa
    26461 tcctctgtat attgcattaa ataaggaatg atagctggat caatatcccc tgtacgcgtt
    26521 cccatcataa taccaccaag aggagtgaac cccatagaag tgtctacaga tttgccggct
    26581 ttcacagctg taattgagcc tccgttacca atatgacagg taattaactt caagtcttct
    26641 aatggacgtc ccaagagttt tgcagcttct cctgctacaa actggtgact tgtaccatga
    26701 gcaccgtatt tacgaacctt gttttctgtg taatattttg ttggtagagg gtagcgataa
    26761 gctttctctg gcatacttgt gtggaaggaa gtatcaaaaa caactacact ggtaatgtct
    26821 ggcaacaatt ccttgaaggc acgaacacct gctgcattgg ccgggttgtg tagaggagcc
    26881 aacaaactca actcttcaac tttttctaaa acatctccct caacaactgt tgattctttg
    26941 aaatattctc caccagcaac aacacgatgt ccaacacctg taatctcgtc ataagccttg
    27001 ataatatcga aacgaatcaa gtcatccaat aaaattttaa cggcttgtat atgattttca
    27061 atatccaaaa tttgttgttc agaacggccg tcaaatttta cagttgaaat tgaatctttc
    27121 aaaccgatac gttcaatcaa acctttcgcc aatacttttt cttctggcat taagtataat
    27181 tgccatttca aacttgaact tcctgcattg attgcaattg tttttgtcat aacatgatac
    27241 ccctttttaa gcgttttcaa ctattataac aaaatctatt ttatatttca gtaccttgag
    27301 tccatttttg aaaattttct ttaaatttca ttaaaacact tgcatcttgc aagctagcaa
    27361 gtggataaac aaaaggctct actgctattt catttttctt ctgtaagata aaaatagtct
    27421 tagattgttt ggcattagca aagagatttt caggcagact aatcatagca accagactcg
    27481 cctcttcttt cagccattct tttaacaaat cactttgagg actggtcaac aaatcactcg
    27541 gagctagaaa aatagcgtat ccgtctgact tgaggtactt aagcccttgt tccatgagca
    27601 agtgatgggc gtaagtatgt tcttggctag aagcaacttg atggcgcgac gcaacggcat
    27661 catcaggata atagccgaca ggcaagtcac tgatgaccac atcgctttct ttgagcattt
    27721 gtgggcgaac ggcatctcct tggacaaagc cagcctgcaa accaattaca tctgccatgc
    27781 tagctgccag atcaatcagc aaatcatcca cttccattcc caagtaatcc acctttttag
    27841 taagcgaggt caagaaaata gcgcctagaa ttcccatccc agaacccatt tcgaggatag
    27901 taatttcctc ctctttaaac aactcttcca caataaacac caaaagcaaa gcaatagcat
    27961 ccggtgtaaa ctggtgattg gcctgcaagg gttctgtttg cccagccttc atcaagagaa
    28021 actggtaggt cttgagccat tcttctttgc gtagtgctaa acgcttaagg gtttgattgt
    28081 tctccttgac ctggtttagc tcagtttcac catccagata gatgctattt tgctccacca
    28141 aggcgtcata aaagttggtc gccaaatcac tttggatgac ttggacattc tctagtaaat
    28201 aggtataagc ttgttcaatt ttttcaaaat ccatattcct atcttaccaa atttcccttc
    28261 ttttttccat ccttatagaa aaatcactcc ctgactaggc gagtgatttt tgggctacta
    28321 ttaaaaagaa ttctgagtga tttccttgaa acaggtcttc agcactatag agaatctgac
    28381 tatgcacaga tgaaaaacca tgctcaatta gcttgttttc cagttcagct aaatcaaatc
    28441 catgatgatt agcttctgtc ttggtaaaat cagcaatgat gagtttccca tcttccttca
    28501 aatgttgatg aaacagtgag agagccgcat ccaaatcagg catatgatga agaacccgac
    28561 taacagcaag gcaatcaaac tctttctcca agggattttt cggtaaatct tgctccaaaa
    28621 actggatatt cttgattgct tgctgctcca ctttcaaacg agcttgctcc aacattttct
    28681 cagaaatgtc tacaagagtg actgacttag cctgcttggc taggggttag gggcaaggct
    28741 aatagacccg tgccaccacc gaaatctaaa atttctttgt ctgatagaag atcaatctgt
    28801 ttctcggctg cttgacatac caagtttgcg aggaagatat ttttagggga atcgaaagtt
    28861 tctgctttgt ggttaaaatc atgtttcata tctttaattt agcacaaagt atagtaaact
    28921 gaaataagat ataaacaaat gaattggagc ttaacatcca tttccagcaa ttttctagaa
    28981 actacagtgg actattctgg attcaacgca ttatagttga attgactatg aattctcttt
    29041 cttttcaggc ttctcttctg attttttctt ctccactttt tcgcttgaat cggtcgctac
    29101 ctcttccttt ttatctcttt tctcttcttt gattttgact gaaggaaaca gaaactcata
    29161 ttggctctta tccgtacgaa ccctcgtcac taagccagtt ttcttgtttt gatagcttac
    29221 ctgacctaga ttaaaaaact gttccccact ttcttgctca accttatctt tggttcgttt
    29281 agccatagca aaagcaacca atttttcttt attcaaagca tagtcttgat agtgggcgac
    29341 ttgtcggttc aaataaaatt gcaacaaaag actaaagatg gctgctatgg tgactgcgta
    29401 gaggagaaca cctgccttaa cttttttctt tttccacacg atggatgaac tccctttcta
    29461 agcctttttg gaactggaaa tgaaagcgaa ccagttgatt gtcctctgta atccgtacag
    29521 atttgagtcc ataaaccata ggctgataac ctcgaccacg agcattcgtt ttacggaaat
    29581 catctgactt tgacttaccg atggcgatgt ccttgccatc ttgcttcatg tataggcgat
    29641 tgccttctac tttttcgaac tgcgaacggt ctaattctac ctcaagttgg tccacaaaca
    29701 agagccactc cttttgctcg ctttgttgct ggtagcgaac ttctgaaatg aggagctgac
    29761 tcatagcttg aaaaaggagt aatcccccac tgatgacaat gagggcaagc agggattcta
    29821 acaaggtaaa agccttgacc ttatggctct ttgattgcca acaactgttc tgaaccatgg
    29881 tagacctcca atcctttttc actagaaaat acctgaatct caactccgtt gatgcttacc
    29941 tgattttgcc ccgtctgcag ggccatctta gctaccctca agacttcttc cttttgcaag
    30001 atttttgctt cctcttgcct atttttttga atttgtccca aaaggagggt cgcaatgctg
    30061 gcaaagatag ctagagcgac tactgcttcc agtaaaatca ctgccctaat tttttgtttc
    30121 cttaatgcgt ttaatttttc catttcctag atataattga tagcgaatcg ctcctttact
    30181 ggtctgaaat tcaaccttag ccagggacga attgccccca gctcggtcaa atgtaatact
    30241 ttggcctgat ggtgcctgaa ttcctttagg aactgtcaac ttttgactgc cattgctaat
    30301 catctgccca tccaagttca gactagtctt ttgctgactg gctacactgc gtttttgggt
    30361 ttcccgatag agttcttcaa actccataaa gaaaatctgc tcctctactg ctgcaaaagt
    30421 ggactggaca gagctggata agcccaaggc aaggatactc acaagtccca aaaccaagag
    30481 actttccagc atggtaaagg ccttaatcat tgactttacg atttgcccct ccatttttag
    30541 tatggtattc tttataggct ttagcctgtt cctcggtgat tcgcccatct gcttgtaact
    30601 tgtttaggct agcctcttca ttttttccca aactataaag ctctgcctgg ctttctacca
    30661 ccttaacaac agcagctttt cctttgtcgt tgactgcttc tttttgcttg gtcagattag
    30721 gtacaaagag caagagaagc acactgatga ttaaaaggac cactaacatc tctaccagag
    30781 tgaaagcttt aaccttagct tttttcaaga atgtcatcat ttttttcatg ttaaaaattt
    30841 acctccatat tttgatacat gggcatgagc attgccgcat aaagtaaaac gataatcagt
    30901 gccacaaaga taaaaaccag tggctgcacc aaattcatgg tgcggttgac tcgggtaaaa
    30961 aaggcttccc aagttttttc agcatagatt tccaactcac tacccagctt ggacttgact
    31021 tccccatact cgataatgag actcaactcc ttcttaaaga aaggataggt tgctatggtt
    31081 tgagaaaatt cgcggccatt ttgtagggat tgagctaaat cttgaccgat ttctttaaag
    31141 agatgggaac cttgttcctg catgatttga aaaatctgcg tcagctccat tccctgcgaa
    31201 atcatattac cccattcacg cgcataataa gctgtcagat aagtctgcac aaagattcca
    31261 agaaagggaa ggcgtgctaa gatagaaaag acgcgcatct tagaacttct tttataaaaa
    31321 gttagtgcta aaagggcaag cacggaaaca agccctacca tgcctagaaa aatttgtggc
    31381 agattaccga taattcgggt ggcaatattg ctactatcca gttgtgggag caggtaattc
    31441 cgtagcccca gcataattaa gagaagaaaa cccagcaaaa tcaaaggata ggtcgctact
    31501 tcaattaact ttttcttgac cttggccaga ttgtctagat attcttctat ctttcccaaa
    31561 ctcaggtgaa gattgccatg aacttcagct agagataact gagtgacaat ggtacttgaa
    31621 catcccaaac tttccatcat ttctgagaat gatttcccct gagacaagcc tgtacgcatc
    31681 tgggtcacac actgcttgtc caacaaggaa ctcctatcta aaaaggagat agtctccacc
    31741 agatgaaaac cgctagaaaa gagattgtta aatagggtga tgatattttt ttgcttagct
    31801 gtagctaatt ttttccgtct cagcctgaag acttgtgata tgtccatctt taagaagctg
    31861 gtcaatttgc tcattccact tggctgcttg gtgttcttga taatctctgt ttgcaaagtc
    31921 aacgattcct cctcccccga ttaatctctg gtagcagact ccttgcagaa caactgccaa
    31981 ttcttcttca ctcacaccca actccagcag acgctcataa acacctcgga tactcttggc
    32041 gtgaatggtt gaaaagactg tcgcacctgt caaactagct ctgaccactg cacgcgccgt
    32101 ctcgctgtca cgaatttctc cgataatcaa gagatctggt cgatgacgca aggaaagttt
    32161 gattagattt tcataggtta ggccgattgc ttcgttcaac tgcaactgaa gcatgtcgtc
    32221 ctgcttgatt tcgacaggat cttcgatgga cataacttgc tgtcctttaa agagtgactt
    32281 ggacaattca tgcatcaagg tcgtcttacc actcccaacc ggaccagcaa aaagatagag
    32341 tccccgttgc ctgtactgct tgcctaattc ttcaatatcc tgaaaccaaa aatgcaagtc
    32401 ctgctcctca tcgtgcaaca aacggataac caaactctca tgcccccgat aatcgcctac
    32461 agtagataaa cgtagagacg ccatcttctg gtcataggca taatcacagg aacccagttg
    32521 actacgtctt ttttctccca cattcatacc cgccacaaac ttaaagtgac tgataacggc
    32581 tgcaaacttt tcaaaatcat agctaccaat tttacagcgc tcgtctccta ccctcatatg
    32641 aagctcatag gcatctaact tggggacaaa ataaatgtct tgcgcccctt ttttccgagc
    32701 cgaacgaatg atttcttgtg caatttcttg aaccatactt acctcctcac ctatactatt
    32761 cgcaaagcgt tagaaaaata aaaaaagcaa ctccaaaaag ttacttttct ctattttaat
    32821 ttcatacggc aagaacgatt cctttcctga ctggtttgtt tttcatagcc tgagcgtagt
    32881 ttttcgtctg ggataacctg ctcatcctgc aaaagagcca aagaatggta ttgttgtaaa
    32941 tactcatcac attcatcaca ccagcgttgg tcttccgggt cccaaaaaat ggtcatcaag
    33001 tcgcttctac ttttataaag aggcgattct tgttccaatc taaaccagca agttttgtag
    33061 tatttgagag catcataata ctggtcaaat tttctacttg ctacaatatc ttcttcccaa
    33121 ccttctaaga accaccacgg ttcaaaatct ccgtacattt ctataacacg atacatattc
    33181 attcattcct ttgtaccgta tattataacc aattccgcca gacaaggaaa gaaatatgct
    33241 catttcttaa ttttttgata aaaaatccaa ccatctgatg gatgactgaa tttctattta
    33301 cttatgtaca aaaatatttt tactacttag gcttctgaga tatcgttttc gataatgacc
    33361 ttaatggcat ggtggtctgc tgccttactg aagacttcgt aggctttttc aatttcactg
    33421 agtttgaaat agtgagttac caatttttcc ggttcaatct tatgactttc aagtgctttc
    33481 aacaattgtg gagtcgtatt tgtagatacc aaaccagttg ttacattgat gttgcgaatc
    33541 caaagtttat ctaaatcgaa ttcaactggt ttaccatgca caccacagtt ggcaaccgtt
    33601 ccgtctacac cgataatctt ttgacagaaa tcaaatgttt caggaatccc tacagcttcg
    33661 atagcgacat ccacaccacg accatctgtc aaatcataaa tttctttaat ggctttttta
    33721 gggtctgaag aattaacctt atgagtcgca ccgaatgata gggcagtttc caagcggtta
    33781 tcgtctaggt ctaccataat caatttagct ggtgaataga attgggctgt taaaagagca
    33841 gccaatccaa ctggacctga accaataatg gctacgctgc aaccaggttc tactttccct
    33901 tttaagacac caatttcata tccagtaggc agaatgtctg acagcataac caaagcttca
    33961 tctgacaagt cttctggagt atggtaaaga gtattatctg catgagggac acgtagatat
    34021 tcagcctgca taccatcaat caagtgaccg aaaatccagc ccccttcgtc ttcacagtgg
    34081 gcataaattc cttttttaca gtagtagcat ttaccacagg cacagacgca agaaatcaag
    34141 accttgtcgc cttttttgaa gttggaaact ccttccccaa cttcttcaac aatcccaatc
    34201 ccttcgtggc caagaatggt accactttgg caagtaggaa catccccttt gataatatgg
    34261 aggtctgttc cacaaatagt ggtttttaca atacgcacaa tagcgtctgt tggcttgcga
    34321 ataactggtt tgtctacatc aacaaaagaa gcaagtcctg gtttaacata agtataggct
    34381 ttcataaagc actcctccgt ttttttattt gtaatattta tagttcaatt gtaagccttt
    34441 ttctttgttt cttcaagctt tttttgtgat ttttttaact ttttatttac cagtaaagta
    34501 ccctgtataa aaaagcagaa gctagtctct aacttctgcc ttctctctta tgcttgataa
    34561 cgttttacgc catctagata ggttgctacc aattccaaat ctttatctaa tacgatgaag
    34621 tcagcgtcgt agccttcacg gatttggcca cagacgtcat cgatgtgaac ggatttagct
    34681 gggttgaagc tggccatcat gactgcttca tgcggattcg caattcccca ttcgaccaca
    34741 ttcttcaaac catctttgag tttgaggata gaacctgcca agttacctgt cgatttgagg
    34801 cgtgcagttc catttgcaac gacaactggg aattctccca acatataatc tccgtcttcc
    34861 aatcccccag ctgtcataca gtctgtgata agagcgatgt tttctgttcc tttttgtttg
    34921 ataagaattt cgcaagcctt tggatctacg tggtgaccat cacagatcaa ctctgcatag
    34981 gtatgtggca attggtacat ggctccaacc atacccaatt cacggtgagt caacccacgc
    35041 attccattgt aggcatgcac ccaaacactc gctccagcat cgactgcttt tttggcttca
    35101 tcaaaagtcg cgtttgaatg tccaagagca accgtcacac cttcgcccgt aactgtacga
    35161 acaaagtctt ccaccccatc acgttctggt gcaagggcaa ttttattaag caagccattt
    35221 gccgcttttt gccaagaatg aaactcctca acacccgggt ctctcatata agttggattt
    35281 tgtgccccct taaaagtttc tgtgaaatat ggaccttcat aataaatccc acgaatctta
    35341 gcacctgttg cttctttata atggtttcca agattttcag tgactgcaag caattgctca
    35401 taagtggctg ttaaagttgt gggtaagaaa ctggtaacac cggtactaag aagtccttca
    35461 ctcatagtat gcaatgtacc ttcaatgttg ttgtccatca catctacacc tgcatatcca
    35521 tgaatatgag tatccacaag acctggggca atgctataac ctgtatagtc aatcacctca
    35581 gccccttcag gaatctgctc tacatgtttc ccaaacttgc cgtccacaag ttccaagtaa
    35641 ccacctcgac gaactccgtg tgggtagaaa aactgatccg ctttaatata gttaggcata
    35701 atgttaacct ccttaaaaga ttgattctac aatttattat gtcaattaca ttataaacct
    35761 ttctttttta tttgtaaatg gtatagacct attttttgga gatattttaa aagagctgga
    35821 tttctccaac tcttctcttt tttaatacaa gttattttga tttaaccggc ttgtcttgag
    35881 ctgtctgcaa agctgtggca atcgtatctg catacaattt tgctcctgct tcgatagtgc
    35941 tactctcact cccgaaatga acctggtctg ttccagccca aatttctgga tgctctttcg
    36001 caacttgatt ccaatctgct atcgtaatgt aaggtgtctt ctctgccaat tctctcatat
    36061 aggcagcagc cttctcaacg atggcatagg tctcttttgt cttatctccc tcataaggag
    36121 tcaccaaaat catatggtgt cccttaggaa gatttttcac gatactgtcc cagtcatcct
    36181 tgtaattctc aggattattt accccagtcg caatgaccac cgtcttaggt aaaaatttat
    36241 tctggctatt atttagcatg atttcatttg cggtcttggt tgttacgctg acctgcgcgt
    36301 taatctgtgc tccaggaaga gctgtctgta gtgctgtatt tgcccttaaa gccactgagt
    36361 caccaattaa catagtgcca tcagcaattc ccaaactgtt tgcatctgcc cgttctgcca
    36421 tcaccttggt ctggccaata tttgttgcag cttgcttcaa gccattgaca gtcaagtctg
    36481 tctcaaacgc tcccacttgt ggtgccaaca aggtcaccgt gcagacaatg atggtcaaga
    36541 ttcctgtacc tgctacaaga attgcgtgaa tataaggcag gggacgaaga gtttgtaaaa
    36601 taggtgtgtt cttgcctgca atccaaggtt ccaatacata gaatgacaga ctggcaaagc
    36661 cataagaaca aatcagagtc agtaatacag caagaagatt tgatgtcaac tgtgagaaaa
    36721 tgatatagaa aggccaatgg aaaagataaa ccgcatagct agtatccgct aaaaagctga
    36781 taatcttcgg ctcctgtata tgatgtgtct tttcatgtaa gacacgcgcc gccagaatca
    36841 tggcaagagc tgcaagactg gcaagcaaga agccgataag ataggcaaaa agataagtga
    36901 atttgacaaa gaaagtcaaa agaactagga aaccaaagcc tcctccaaaa actaccaaag
    36961 tctttcgtaa atcccagatt ttatccaact gcttgacgag ggaagtcgtc tgacgaacac
    37021 ctacaatagt tgctaacata cttcccaaaa agaatggata gacatgagtt aaactggaga
    37081 aataaacaga ggaataagag gtcactagaa aactaccaat aaacatggag aagaaactga
    37141 tcaagaaggc agcagcagat aagagaaaga ccatcccctt caactgacca tttgatttag
    37201 cttgtttgga taagaaccaa actgccaatc cccaaagaat atagtaatga acctcaactg
    37261 ccaaactcca attatgaaca aacaaatgag gaatgaactg agattcataa ctcccacctg
    37321 ttaggagttc atagaagttg gtcataaagc ctaagacgcc cgcaatctgg ccaccaattc
    37381 cagcaacata gtcttggcga accaagaaag taaaaggcat ggtcaccaag accatcaaaa
    37441 ccacaggtgg cacaatccga taaaagcgtc ttctaaaaaa tcctatcaaa tcaatctcat
    37501 ggtttttaga aaattcttca atgagtagag ctgtaatcag gaaacctgaa aatgtgaaaa
    37561 agacatctac cccgaaaaat cctccaggaa agatcgtctg aaagaagtga tacaagagta
    37621 ccaaaagtaa acctgtaatc ctaatcaagg aaaaccattt aatgcgcata cgagtttatt
    37681 cttcctttca ttgtacactt tattctatca aaaaaagaag aaaaatccta agagaaaact
    37741 taggattttt ttatatcaat tccattttag aaattacgtc ctgacttatt atagccatat
    37801 ttttccacaa aatactcacg gaattccaag agattgtcat ccatgatggc ttgtcgcact
    37861 tgcttcatca ggttaagcaa gaagtaaaga ttgtggtagc tagtcaagcg gataccaaag
    37921 gtttcatcag tcttgagcag gtgacgaagg taagcgcgtg tatagttatt acatgtgtag
    37981 caatcacact caggatccag tggcgtaaag tcctcagcaa actgggcatt tttcacaacc
    38041 aaacgtcctt gactggtcat acaagtcccg ttacgagcaa ttcgagtcgg taagacacag
    38101 tcaaacatat ccaccccacg aatgacccca tcgatcaagc tatctggcgc tcccacaccc
    38161 atcagataac gaggtttatt ttcaggtagc agttgagttg taaagtccaa gaccgcattc
    38221 atctcttcat gggtttctcc cactgccaaa ccaccgatag agtagcctga gaaatccatg
    38281 ctgacaagat catgagctga ttggcggcga aggtcttcaa atcctgcacc ttgcacaatt
    38341 ccaaacaaac cttggtcatg tggacgacgg tgagccttca aaccacgctc agcccaacgg
    38401 ctggtacgct cgatcgattt cttaacgtag tcataaggtt gataaaactg aggacattca
    38461 tcaaaggaca tcatgatgtc tgaacccaga ttattctgaa tagagatggc tttttctggg
    38521 gataggaaca tcttagaacc atttagatga tttttaaagg ttactccttc ttctgtgata
    38581 ttacggctat ctgctaaaga ataaacctga aaaccaccac tatctgtcaa gataggctgg
    38641 tcccaattca tgaacttgtg gagaccacca gcgcgtgcaa tgagttcatc tccagggcga
    38701 agccagagat gataggtatt tgataggata attcccgaac ccatctcctt caattcttca
    38761 ggtgactgag ttttgacagt ggcttgtgtc ccaactggca taaacatagg tgtcggaaag
    38821 gtaccgtggg gagtgatgat ttctcccaga cgagctcctg tgtgtttttc tttcttaatc
    38881 aaacgatatt tgattggtga atctgacatt ttttacctcc gaagctggga aagacagtcc
    38941 cagttcatac agtgtgccca aggacacact gtatgatttt atcaaaaaaa gtaggaactg
    39001 tcacgaacta tgtataagaa ctatggtata ataagagaat gaactatcca aaaattgatt
    39061 taaaaacaat tcgtcaggag tcaaaacatt ttcaggctga caccccccgt ctctttctcc
    39121 tctatatcct tcccagtatg ctggtcatct tatctggttt tcttaatccc ttatctcgga
    39181 tccacgggac tgttttagaa cagccatttt tcagcatact tggccaaata cttcaaacct
    39241 acctctttcc tctactagtc tcctttatcg ggactattct tttgaccagt tccgtctatg
    39301 caacactgac actcatgaaa gattctaaaa cggagccatc tgtaaaaaac agcctagctc
    39361 tctttgatga ggagcgcttt tctcaaacct ttttgaccct acttctcaaa cgtttctatc
    39421 tctttttatg gagtatccct aatttacttg ggatttacct cctcttttat agtagctttt
    39481 tagccaaaaa attcgtcacc ctacatcctg agtttccaaa tctagatctc tcatcagttg
    39541 aaaccgagcg tttcctcatg gtctttggac tctactttct tgcaagtctc atcttgatca
    39601 ttgtaggaaa tatcctctat attccacagt attatgccta ttcacaggtg gaatttcttc
    39661 tctgttatag tctagaccta ggacaggtcc caccaagacg aatcctaaaa actagccgtt
    39721 cctttatgaa gggctacaag ttccagcact ttgtcctaga tttacagctt cttccttggt
    39781 acttcctcaa ttggattacc tttggcattg ctagtttttc actcctacct tatatccaat
    39841 gcactaaaat tatgttttac cgagcagtat tggcccgaaa acgtccaaaa gcttgaaggt
    39901 ttttcccctc aagctttttt ctatcaatga gtttctccgc ctaccaactt gagttcctga
    39961 tctccatgtt ctattatagc gccgattgct gcttctatcc ctcgccgaat atccactaaa
    40021 ctcatagctg gagtagtcgg tctgttcacc acctgttcca tcatataagg aatatgcata
    40081 aaacctgcct taacatatgg agatttcttt tctaccaaat agagagcctg atacatcaaa
    40141 tggctgcaga caaaagtccc tgccgtattg gaaacagagg ccggtaagcc ctcttttttt
    40201 atagcttgaa ccatcgcttt aatcggcaaa ctactaaagt aggccgaagc accatctggg
    40261 cgaatgggac ggtcaatcgg ttgattatct tcgttatcag aaatgcatgc atcgtcttga
    40321 ttaatggtca ctcgttcagg tgtcaaacta gttcttccac cagcttgccc aatacaaagg
    40381 acaaagtcag gttgataacg attcatctct tcttccaata cttgagcaga tttgtgaaaa
    40441 actgtcggca cctctagcca acggacctca gcaccatgga tttcagctgg taaaccttta
    40501 atggcctcca aagctggatt gcccttttcc cctccaaagg gctcaaaacc tgtcactaat
    40561 actttcattt ctaactcctc aaaaccaatt caatgagact tttttcttaa aaacaagtat
    40621 aacatatttc ccttattctg gattaaaaag gattagcgag attagaatcg accttcaagt
    40681 gtatttaaag agtaaaatac taatcaaggc caaaatagct gatccacctt gtttcaaaat
    40741 aattttttta tccgctgtta aagagccgta agtcgcagca ccaatcacaa ataagacaaa
    40801 aatagtcaca atttctaaat tctgtgagaa ataaatgaca tacaagagaa agactcctag
    40861 cagagcctta taaattcctt gatttttgaa caatgaactt actgacggat gagccaattc
    40921 ttccttttcc atattaaata cacgactagt cgcatctgat tgcgtggcaa tactttccaa
    40981 ataaaaaatg taaaaatgct ccaaagcaac gatcgttgtt aaaataattg acatctattt
    41041 ctccttaaat ttctatattt tcaataccca aaaccaattt atttaataaa cggctgagtt
    41101 ctgttctctc aaactctgtt aagatacttt ctatctcttc cttaaccctg atatgttgca
    41161 gagggggatt caccactaac tgctccttgg catacttcgc agcctctacc aacacttccc
    41221 gctgattttc aggattacga tgacgctcca ccaaaccttc cgtttccaaa attttgaaat
    41281 gccgtgtcaa agcagcctga tcaattttca aacgctcctg aaccgccatt tggttacaag
    41341 gagaatgctc cagcaaaaac agtaaaatct gataccgtgt caaactaatc ccaagccttt
    41401 tttcaaacaa ttgcgtactc gcttgctcag acaagcggag ttgatacagt aaatcttgaa
    41461 tctctagcat ttcttcccct ctctttttat tgatttatca atatttgact aattaattgt
    41521 gatataaagt aaaatagatt gcaagaatgt tgcttaactc attacaagat gataactttc
    41581 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    41641 aggttgctca aagcacagct ttgaagtttc agataaaact gacgtggttt gaagagattt
    41701 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt tccatcacga aagctagatc
    41761 tcattcgtca aaatgatgtt atcaagtcgg gtttatccat tcattgaaac gtgaacgtga
    41821 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    41881 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    41941 cggctggcca tattttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    42001 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    42061 ccactaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    42121 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    42181 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    42241 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttacttcc
    42301 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgtttcc
    42361 tgaggagttg cttcttcaac tgggcgagtt gtttcggtcg tttgctcctc tgggacagaa
    42421 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgcaatt
    42481 ggttgagaaa ggtctgcaac ctgaacagtt tgatcatcaa cggtcacttg attagtggtc
    42541 aaatctgctg tcgcagttgt cacttcttca ctagagtctg cttgaggtgt ttggatttca
    42601 acttctgtta cttcttctgc ttcattgaca gtcgttgtca aaacagtttc tgggaaaatc
    42661 aagtccatat tagtgatttt gttcagattc gcaagcactg ttacatctac acccaaggct
    42721 tctgcaatgg tgctcaaagt atcaccatac tgtacggtat aacttgtttt gttgtccgtt
    42781 ttagtcaaat cgttttggat ttgctcaaca ctacgtgcag tccaaagaac ttcttctgct
    42841 tgagttgcca atactggggc aaatgacaag gctactgttg acgctaataa cattcttttc
    42901 ttcattcttt caaattcctt tcaaatgagt acctgtctat cataacacaa aaaatgtaga
    42961 aaaaaagccc tctcgggcct atttaacaga actgtctatt ccttgtaaca aactaggtta
    43021 cttgaaatag tttgttaggt ctctgtcaca aaactgacac aatcttttta tcacttagtc
    43081 tcaaaaatac gggaaatatc tgctaacgct tgaatcctgt gattcccttc ataagtagac
    43141 tctaaaaagt tgatgctttg aatcccacta ttctgggcaa attccacatc cagagtccga
    43201 tcccctatat aataagtatt atcagaattc aactgatact tatctagcag ataggtagcc
    43261 gcttctggac ttggcttccg cacaaagcca ctctgactgg ttaaaatctc tgtaaaatag
    43321 gattccaccc ccaagtcctt gagaatggta aaagcgttgt tccccttatg agtatatata
    43381 aactgctgaa ttcctgattc gtctgcccaa gctagcacct cacgcgcacc tggcatcaaa
    43441 actacctgag cattcttctc agccagactc tgggcacgca cctgatttag cacctcaaca
    43501 tccagatttc tatcttctgc cacccgcaca agcaaatctt gcaccgaata cttgaagata
    43561 aactctctca ccttctcctt atcataagga atagaaaact gagcaaaagt ctcctcaatc
    43621 cctgataaaa tcgcttcgta agagtccaat aaagtcccgt ctaaatccca aataaaagct
    43681 gttttttgca tttcctatcc tttcaagctc atatagcgct ggtaacgata gcgtagaaat
    43741 aaccagcgaa aaccattatc caagagagac cctgcccaaa taccaggcaa gccccaacca
    43801 agcacaatcc ccatcagata tcctgtccca atgcggatac accacattcc tatacttgtc
    43861 gcataaaaag ggaggcgtgc atttcctaat ccctgccaga ctgccgtata gatgactgtt
    43921 cctgtcgtca taggggtccc aagtagtgaa aacagtgtca ctagaacact agcctccacc
    43981 gctagagaat cagtcgtata gagatgagtt aatggtacac ccaagacata tatactaaag
    44041 gacaggggca acatgaggaa cagagaaagc caaaaggttt gtttactcaa actagcaact
    44101 cttttccaat catcctctcc aactgctcgg gccaacagca tgaccgttgc cgtagcgacg
    44161 ccaaaggcag gcatatagtt aaactgggtc aagacttctc cgattgcatt cccagcaact
    44221 gcctccgtcc caaaagaaac gaccaaggca atgatcacta catctccagc cctcatcata
    44281 agtcgctctc cagctgctgg taaagccaag gtcaacagtt ccttatctaa accaaaagtt
    44341 ggcttcccat aaggcagttt taattgtgac cacaaaatca caagaccaac caaacgagac
    44401 acaattgtcc cccaagcaac accagctatc cccatatcca gaacaaaaat agctagactt
    44461 gaaaaaagaa tattcaaggc attggataaa aaactaacat agagaggcag acgtggatta
    44521 tgcgttgcac gaatcaaggc tcctagacta gtcattaaac ctaagagaac aatcgatccg
    44581 cctaccaaag atagatacag tccaccactc tcagctacat ccctctccgt ccccaaaagt
    44641 cctatcatct ctttcccagc gaagatggac aaaaatccta aaaggaaact taatagtaag
    44701 gtaatcttca acgcctcagt cacatgatag gccaacttcg actggtcttt ctgccctatg
    44761 ctttttgaaa taacactgga aatagcagct cccagagcga tgaaaatcgc ctgataaatg
    44821 gtgataatat taccagctac tgaaacccct gaaatagcta tcaatcctaa atgagcaacc
    44881 aaataactgt ccaccattcc cattagcatc tgcaaaaagt tttcacccat agctggcaat
    44941 gcaatattaa gaatgtcttt atttttctta aacaatctct cctcctgatg aaaagaaact
    45001 cagttggttt cccaaccgag tttgctccct ctgtcttaaa gtcctaaata agcctcaacc
    45061 gctgcttgca tgtcagcagc tgccactgtt gtcttgtgac gaattggagc tatttcaagc
    45121 ccatcaactg ctggtggcac tgcaacgcct gagatttcat gtaattgagc caaggcttca
    45181 aagtctgtta aacctgcttt tccagttaca gcttctactg caactactgg gaacttgtat
    45241 ggactagctg ttgaagcaat cactgtctta gttacatctc cagtggccga ttggtatttt
    45301 ttataaactg ctgaagcaac agctgtatga gggtcctcga tataagaatc taactcacaa
    45361 acacgcttga tctctgctgc cgtttcttcc tcagtcgcat attcagctgc aaagaggtcc
    45421 aaaatctctg catcaaagtc tgtcaactta tattgtcctt gcgtgttcaa ggcattcata
    45481 agttcagttg tcttttcagc attatttccc aaaagatgga aaatcaagcg ctccaagttt
    45541 gaagatacca agatatccat agatgggctg gttgttacct taaactcacg ttttttgtca
    45601 tagacacgtg ttttaaagaa gtctgtcaaa acattgttgt catttgaagc acagattaat
    45661 ttaccaactg gcaaaccaat ttgtttggca taaaaggcag ccaagatatt tccaaagttt
    45721 cctgttggta ctgtgaagtt aaccttttca ccagctacaa tttcaccagt cttaaccaat
    45781 tgagcgtaag cataaacata ataaacaatt tgtggcacca gacgaccaat gttcatagag
    45841 ttagctgatg aaaattgcaa cttgttggta gtcaattttt cacgaagagc cacgtcgtta
    45901 aacatgtgct tcacatttgt ttgcgcatcg tcaaagttac catcaatagc aataacatga
    45961 gtattgtcgc cagtctgagt ggtcatttgt aactcttgaa tcttgctgac accatccttt
    46021 ggataaaaga cgataatctc agtaccaggc acattcgcaa accccgccat agcagctttc
    46081 cccgtgtcac cagatgtcgc tgtcaagata acaatcttgt tctccaaacc atgtttctta
    46141 gcagcagtcg tcataaagta tggcaaaata gacaaggcca tatccttaaa ggcaatcgtt
    46201 gaaccatgga aaagttccaa attgtattgc ccatctaatt tcactaatgg tgcaatagct
    46261 ggagtatcaa atttgctatc gtaggcattg ttgatacagt agtccaactc ctcaactgta
    46321 aagtcatcta aaaatgctga caaaactagc ttagcaactt cctggtaaga agcatctttc
    46381 aatttgtcaa agttcaaatc tacctttgga taagtatccg gtgtaaacaa accgccgtcc
    46441 gtcgccaaac cttgcaaaat tgcttggctg gcagttactg tattgttggc atcacgcgtt
    46501 gattgataaa ctaatgtcat tactctctat cctttatcta tagtctcgtc cattatatca
    46561 tgatttttca gaaaattctc cctttataag agaaattata ggctcaattc ttctctcaaa
    46621 ggctgtaaat aggtcatttc ttccttattt ctcaccacta gtccctcctc agctagtagg
    46681 agtaagtctt tggaaaattc aataatcgta gtttcttcct catctgtaag atttttctta
    46741 gaaaattgtc tccttaaaga cttgtaatca taaccaaata ctttaaagaa aggtgctgtt
    46801 tctaagtaag cttctaactt gtctaaatta accaataatc ccaagtgaaa agctgcagaa
    46861 gcaaaagtcc tatcaagtgg ctgtgtacac acactacgaa actcaactgt tcctcgagtc
    46921 gttaaatctt ggtactggta actacgatga gtttcaaaat ccttctcttg ggggtaaata
    46981 ataacctcat ccccattcag agcaaatgct tggatttcgg acgtagccaa atagtcccca
    47041 gcctgaatag gataaaaata ataggtctgc ccatcacgtt ccgcagtaaa aatcgcagaa
    47101 tgatttagat agtcaaaaaa atcagcttca tcattaagga gtctagcatt gaccccaaca
    47161 ttctctggat agataccatg catagattct tcccagaaaa tatcccttga aattttcgta
    47221 tcccaatccg cacccgaaaa ttcagagttt gcaaataaat aagccttagc cgcttcaatt
    47281 tgagtaaaag cattaatcac ccgtaagtag ttggtttttg aaatatccag ctgaacctgg
    47341 ctcccacaga taaaagtacc atattcaggg aaatgatgta aatctgattt aataatattt
    47401 ctactcaaat tcaaataatc catcaacatc tgatagcgtg gataagccac tggacaattc
    47461 tcatttttat cccagttggg atggatacca cagccaacaa tagcatgatt tgattcagct
    47521 aactttctct gaattacatt catataatta ttgaaacgat tttcgacctc ttgaatcgtt
    47581 tcagccttac caaatgcaaa ctcaatcgtt gtataggaaa cttcaaataa aatagcatcc
    47641 tgacttatcg gatctactaa ctggatcaga ttgccaaaat catctacctt tgctacggtg
    47701 agatccaaag tagaaactaa ataatgaaat agatccttca taacttcaac atctgtagca
    47761 tccccttcta aacttgcaac aggatactcc aactcaattc cgacaaacaa ttcagaattt
    47821 tctttaatat ttttcaaata ccgatgtttt aataaatcga tagaacaaga catactcccc
    47881 tacactttct taatctaaat aaaatttgaa taactataat tataccaaaa ataatataaa
    47941 aaaggaacga agaataacaa cgttcctaac actatactat accggcggcc ggggtcgaac
    48001 cggcacgtcc ttgcggacac tggattttga gtccagcgcg tctgccaatt ccgccacgcc
    48061 ggcaaatagt aactggggta gctggattcg aaccaacgca tgagggagtc aaagtccctt
    48121 gccttaccgc ttggctatac cccaataata taaaataggc gagtgatggg gatcgaaccc
    48181 acgcatgcca gagccacaat ctggtgtgtt aaccacttca ccacacccgc cataattcta
    48241 ttaacacggg cagtaggaat tgaacccaca ctgaaggttt tggagacctt agttctacct
    48301 ttaaactatg cccgtaaaat ggaaggggag ggattcgaac ccccgaaccc gaaggagcgg
    48361 atttacagtc cgccgcgttt agcctcttcg ctacccttcc aaaatatata aatggcgcga
    48421 gacggaatcg aaccgccgac acatggagct tcaatccatt gctctaccaa ctgagctacc
    48481 gagccttatt gcgggagcag gatttgaacc tacgaccttc gggttatgag cccgacgagc
    48541 taccgagctg ctccatcccg cgttaatata aaaggaggat gtgggattcg aacccacgca
    48601 cgcttttaca cgcctgacgg ttttcaagac cgttcccttc agccggactt gggtaatcct
    48661 ccaaaatagt ttatacggga acaagcccgt gtcctcttag tgaacagata atattccaat
    48721 cccctagtaa tggactaaac actatgggca cgagtggact cgaaccaccg acctcacgct
    48781 tatcaggcgt gcgctctaac cacctgagct acgcgcccaa gtcaaaaact tggtacaaag
    48841 aacaaagttc aaagcgggtg acgagaatcg aactcgcgac aacagcttgg aaggctgtag
    48901 ttttaccact aaactacacc cgctaaa
//
LOCUS       DAVEHY010000016        45791 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVEHY010000016 DAVEHY010000000
VERSION     DAVEHY010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.016"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(178..981)
                     /locus_tag="VUZ44_001066"
     CDS             complement(178..981)
                     /locus_tag="VUZ44_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU0319988.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1264..2019)
                     /locus_tag="VUZ44_001067"
     CDS             complement(1264..2019)
                     /locus_tag="VUZ44_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU0319989.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCFSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPCFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2089..4740)
                     /locus_tag="VUZ44_001068"
     CDS             complement(2089..4740)
                     /locus_tag="VUZ44_001068"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU0319990.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPVFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(4733..5311)
                     /locus_tag="VUZ44_001069"
     CDS             complement(4733..5311)
                     /locus_tag="VUZ44_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU0319991.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5311..5871)
                     /locus_tag="VUZ44_001070"
     CDS             complement(5311..5871)
                     /locus_tag="VUZ44_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0319992.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKILEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(5858..6307)
                     /locus_tag="VUZ44_001071"
     CDS             complement(5858..6307)
                     /locus_tag="VUZ44_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEU0319993.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6719..7114)
                     /locus_tag="VUZ44_001072"
     CDS             complement(6719..7114)
                     /locus_tag="VUZ44_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU0319994.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7210..7464)
                     /locus_tag="VUZ44_001073"
     CDS             complement(7210..7464)
                     /locus_tag="VUZ44_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU0319995.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(7474..8808)
                     /locus_tag="VUZ44_001074"
     CDS             complement(7474..8808)
                     /locus_tag="VUZ44_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU0319996.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8808..9041)
                     /locus_tag="VUZ44_001075"
     CDS             complement(8808..9041)
                     /locus_tag="VUZ44_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU0319997.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            9072..9146
                     /locus_tag="VUZ44_001076"
                     /pseudo
     CDS             9072..9146
                     /locus_tag="VUZ44_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9501..9683)
                     /locus_tag="VUZ44_001077"
     CDS             complement(9501..9683)
                     /locus_tag="VUZ44_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319998.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9685..10464)
                     /locus_tag="VUZ44_001078"
     CDS             complement(9685..10464)
                     /locus_tag="VUZ44_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0319999.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            complement(10743..11093)
                     /gene="rbfA"
                     /locus_tag="VUZ44_001079"
     CDS             complement(10743..11093)
                     /gene="rbfA"
                     /locus_tag="VUZ44_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU0320000.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKVQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(11344..14136)
                     /gene="infB"
                     /locus_tag="VUZ44_001080"
     CDS             complement(11344..14136)
                     /gene="infB"
                     /locus_tag="VUZ44_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU0320001.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(14153..14452)
                     /locus_tag="VUZ44_001081"
     CDS             complement(14153..14452)
                     /locus_tag="VUZ44_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU0320002.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(14445..14738)
                     /locus_tag="VUZ44_001082"
     CDS             complement(14445..14738)
                     /locus_tag="VUZ44_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU0320003.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(14760..15896)
                     /gene="nusA"
                     /locus_tag="VUZ44_001083"
     CDS             complement(14760..15896)
                     /gene="nusA"
                     /locus_tag="VUZ44_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU0320004.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPDRYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(15940..16419)
                     /gene="rimP"
                     /locus_tag="VUZ44_001084"
     CDS             complement(15940..16419)
                     /gene="rimP"
                     /locus_tag="VUZ44_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU0320005.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KTEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(16545..17180)
                     /gene="trmB"
                     /locus_tag="VUZ44_001085"
     CDS             complement(16545..17180)
                     /gene="trmB"
                     /locus_tag="VUZ44_001085"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU0320006.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(17177..17971)
                     /locus_tag="VUZ44_001086"
     CDS             complement(17177..17971)
                     /locus_tag="VUZ44_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU0320007.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(18132..18743)
                     /locus_tag="VUZ44_001087"
     CDS             complement(18132..18743)
                     /locus_tag="VUZ44_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0320008.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            complement(18773..19021)
                     /locus_tag="VUZ44_001088"
     CDS             complement(18773..19021)
                     /locus_tag="VUZ44_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320009.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLDLKNDV"
     gene            complement(19063..19752)
                     /locus_tag="VUZ44_001089"
     CDS             complement(19063..19752)
                     /locus_tag="VUZ44_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0320010.1"
                     /translation="MKKYQLLFKTSAILSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(19784..20017)
                     /locus_tag="VUZ44_001090"
     CDS             complement(19784..20017)
                     /locus_tag="VUZ44_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEU0320011.1"
                     /translation="MDTKMMEQFEIMDTEMLACIEGGDVSGIYRGYAYQDSPFGPYPS
                     ILKNSDPFPVSGYCPRGYRDLGYIGAGFHLCGI"
     gene            complement(20264..21233)
                     /locus_tag="VUZ44_001091"
                     /pseudo
     CDS             complement(20264..21233)
                     /locus_tag="VUZ44_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744512.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21394..21765)
                     /locus_tag="VUZ44_001092"
     CDS             complement(21394..21765)
                     /locus_tag="VUZ44_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320012.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQIMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLIIILFLIWGLKYYKK"
     gene            complement(22234..22353)
                     /locus_tag="VUZ44_001093"
     CDS             complement(22234..22353)
                     /locus_tag="VUZ44_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU0320013.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTP"
     gene            complement(22457..22606)
                     /gene="blpO"
                     /locus_tag="VUZ44_001094"
     CDS             complement(22457..22606)
                     /gene="blpO"
                     /locus_tag="VUZ44_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU0320014.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(22850..23134)
                     /locus_tag="VUZ44_001095"
     CDS             complement(22850..23134)
                     /locus_tag="VUZ44_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEU0320015.1"
                     /translation="MGTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(23203..23472)
                     /gene="blpJ"
                     /locus_tag="VUZ44_001096"
     CDS             complement(23203..23472)
                     /gene="blpJ"
                     /locus_tag="VUZ44_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU0320016.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLVGAFVGAHIGAIGDGLTCLGGMVGDKLGLSW"
     gene            complement(23939..24136)
                     /gene="blpI"
                     /locus_tag="VUZ44_001097"
     CDS             complement(23939..24136)
                     /gene="blpI"
                     /locus_tag="VUZ44_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU0320017.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            24417..25004
                     /locus_tag="VUZ44_001098"
     CDS             24417..25004
                     /locus_tag="VUZ44_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU0320018.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            24931..26574
                     /locus_tag="VUZ44_001099"
     CDS             24931..26574
                     /locus_tag="VUZ44_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU0320019.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHIFINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRL
                     SIAEQTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            26585..27946
                     /locus_tag="VUZ44_001100"
     CDS             26585..27946
                     /locus_tag="VUZ44_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU0320020.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            28003..28131
                     /gene="blpC"
                     /locus_tag="VUZ44_001101"
     CDS             28003..28131
                     /gene="blpC"
                     /locus_tag="VUZ44_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU0320021.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(28202..29542)
                     /locus_tag="VUZ44_001102"
     CDS             complement(28202..29542)
                     /locus_tag="VUZ44_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU0320022.1"
                     /translation="MYIFWIILYTLITNGLEIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(29555..30292)
                     /locus_tag="VUZ44_001103"
     CDS             complement(29555..30292)
                     /locus_tag="VUZ44_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320023.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(30297..30635)
                     /locus_tag="VUZ44_001104"
     CDS             complement(30297..30635)
                     /locus_tag="VUZ44_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320024.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            30912..31241
                     /locus_tag="VUZ44_001105"
     CDS             30912..31241
                     /locus_tag="VUZ44_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU0320025.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKTETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(31409..32458)
                     /locus_tag="VUZ44_001106"
     CDS             complement(31409..32458)
                     /locus_tag="VUZ44_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320026.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(32455..33186)
                     /locus_tag="VUZ44_001107"
     CDS             complement(32455..33186)
                     /locus_tag="VUZ44_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320027.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            33254..33664
                     /locus_tag="VUZ44_001108"
     CDS             33254..33664
                     /locus_tag="VUZ44_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU0320028.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            33674..33961
                     /locus_tag="VUZ44_001109"
     CDS             33674..33961
                     /locus_tag="VUZ44_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320029.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            34123..34407
                     /locus_tag="VUZ44_001110"
     CDS             34123..34407
                     /locus_tag="VUZ44_001110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320030.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTDEVSSKHCFEVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(34729..35865)
                     /gene="dnaJ"
                     /locus_tag="VUZ44_001111"
     CDS             complement(34729..35865)
                     /gene="dnaJ"
                     /locus_tag="VUZ44_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU0320031.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGGLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(36267..36623)
                     /locus_tag="VUZ44_001112"
     CDS             complement(36267..36623)
                     /locus_tag="VUZ44_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEU0320032.1"
                     /translation="MSVLAEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIECLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(36625..38448)
                     /gene="dnaK"
                     /locus_tag="VUZ44_001113"
     CDS             complement(36625..38448)
                     /gene="dnaK"
                     /locus_tag="VUZ44_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU0320033.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGNDVVDGEFTEK"
     gene            complement(38928..39452)
                     /gene="grpE"
                     /locus_tag="VUZ44_001114"
     CDS             complement(38928..39452)
                     /gene="grpE"
                     /locus_tag="VUZ44_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU0320034.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(39479..40513)
                     /gene="hrcA"
                     /locus_tag="VUZ44_001115"
     CDS             complement(39479..40513)
                     /gene="hrcA"
                     /locus_tag="VUZ44_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU0320035.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(40677..41186)
                     /locus_tag="VUZ44_001116"
     CDS             complement(40677..41186)
                     /locus_tag="VUZ44_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU0320036.1"
                     /translation="MNSRVEFRIFTILDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQEFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREELSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            41793..44126
                     /locus_tag="VUZ44_001117"
     CDS             41793..44126
                     /locus_tag="VUZ44_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU0320037.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            44139..45602
                     /locus_tag="VUZ44_001118"
     CDS             44139..45602
                     /locus_tag="VUZ44_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU0320038.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            45602..>45791
                     /locus_tag="VUZ44_001119"
     CDS             45602..>45791
                     /locus_tag="VUZ44_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEU0320039.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT        13933 a         9802 c         8265 g        13791 t
ORIGIN      
        1 cggattttta tcgctctgaa catcaaaaaa gaaaggacga aatttgtcct ttctcgaact
       61 tagcttttct tcaacccact acaattgaca aagagccaaa ctttgatgat atacgttttc
      121 ttgtgagaat atttacttca ttttttccta aaattcaatg tttactcagt atttggatta
      181 tgaaaaatcg aggtctaaat ctagatacat tttttctgaa gacaaatcat tttgaccacc
      241 gagcaagaga ttttcaaaaa aagctgttaa aaactcagga cgtcgctgta aaatctttgc
      301 attatctaat accaaggcat cacgaaaata cttggaatgt tgctgaaatg gtatattatc
      361 aatatcaaaa ccaaactcac gaagatactg aatcaaaaag accgttactg tccgagtgtt
      421 tccttcgcga aatggatgaa tctgccagat tcctgaaata aaatgctgga tttgtttaac
      481 cacatccgcc tgagttagtg tcgcatatgc aacttgtttt tcctgattaa aatcataatc
      541 taaggtcatt tgaatcatgg agtaatcaga gtacacaaca ctttcaccat tcaaaacagg
      601 ttcattcttt gtgatattgg tctgacgaaa ttgccccacc ggaatagagg gttcaaatat
      661 atcttgaaac aactccttat gaatagcaag taaggtcgca ggactaaagc taaagcctct
      721 tcgagacaat agttctacaa tacgtagaga aaccaagtct gcctcttccg tacttgcatc
      781 aatagtatgg tgataagccg ttgcatcctc ataaacctgc tcataagtca gttctccccg
      841 ggactgtttc tcagccaaag attccatata cgctgatggc actagattgt caactttctg
      901 cagaccaaaa cctatccgcc ataaatcacg cttcgcttca taagacaagt ttggattgtc
      961 aatgttgtaa gttggttgca tagaaatatc ctttcaattg tttttcttca ttaccagtaa
     1021 atcacgaaat tggttggaaa ctggcttaaa ctataaaaag tcctcacaat aggttctatg
     1081 atatatatat atatatatac ttcatgtaaa taataaaaga gttataatca gcactactga
     1141 taaattcaat accgatttcg ccatcttaaa acttagtcaa acgaataccg ttgatttcca
     1201 gttcattaag tcgttgacct gtcaagactt ctcgttcctt caactggaaa agttaagggg
     1261 gaactaatac aaatcctcta cgcttctata ttcaatgatt tcatttttga taatattctt
     1321 tttaaactca aaatgtttta aaggattatc gattaacact aactttggaa tatcatctag
     1381 atttgtgacc aaggataaaa taaaatccga ttgaaactcc ttgacttttt caaattcttt
     1441 tgcagttaaa cgcacacgcc ccttagattt tcggatacct tttacttcgg caaggtaaga
     1501 atactcttgg acatctacct gaaagtcata tccatcacca taaagacggg catcggttaa
     1561 ctgtccacct tggaattttt cttctttatc aaaatgaagg ataaaataat tctcagcctc
     1621 cattcccgtt tcctgtagac gtttgaattt agttcgaact attggttttt caacgatggt
     1681 tatgcctgtt ttcttccctt cactggcaag taacatttta actatttcag cataactatg
     1741 aacatcttca tttccaaaca tcatatcaat taaatcttta cgaaaacgat aaacttcagc
     1801 tttctgccac caaccttttc gattattgtc aaaacaagga tcaaataaat ccattctatt
     1861 ttttacaact ccagttgttt cagcaattcc cagagaaacc acatagcgat aaaactccga
     1921 cttgctaaag cattgaaatt cttttataaa aagcttgtca aacttggcaa gaccgtagcc
     1981 aattaaattt aacaattcat aatgagggtg tttggacatc actttctcca tcaatagata
     2041 ttgatttcat tataccaaaa aacacggctc atcaccgtgt ttctgtgttt atttcaccaa
     2101 cttcttcatc tcatcaatac gtgctacggt cacatcatac ttggcttggt agtcggcttg
     2161 tttgtctttt tctttttgga caacttctgg tttagcgttg gcgacgaagc gttcgttaga
     2221 gagtttctta ccaaccatgt ccagttcttt ttgccattta gcgagttctt tgtcgagacg
     2281 agctagttct tcttcaacat tgaggagatc ggccagtggc aagaagattt cggctcctgt
     2341 aataacgctt gacatagcca gttcaggtgc agggatggtt gatgcgattt ccaagtgttc
     2401 tggatttgta aagcgtttga tatagttgac attgctgtta aagaaggctt ccaagtcact
     2461 atcgcttgtc ttaacaagga tggtgatagg cttgcttggt gctacattta cttccgcacg
     2521 cgcattccga acggcacgga tcaagtcttt gagactttcc acaccagtgt gggcagcaag
     2581 gtcctcaaag actgggttga cagttgggta tgctgctgtc acgatagagc cttcagcgta
     2641 ctgaccaaag atttcttctg tcacgaacgg cattattgag tgaaggagac gaaggatttt
     2701 atccagcgta tagaggagaa cagatcgagt aattacctta tcgtcttcat tgtcgctgta
     2761 aagaacttcc ttggtcaact caacatacca gttggcaaat tcttcccaaa tgaagttgta
     2821 aaggatatga ccagccacac caaactcgaa cttatcaaag ttttcagtaa cttttgcaat
     2881 ggtttcgttg agattgtgga gaatccagcg gtccgtcaca ttaccagcct cacctgttgc
     2941 aacttttgtg acattgtcat gcgccacatc cagcgtcaaa cctccattgt tcatgaggat
     3001 atagcgagaa atgttccaaa tcttgttaat aaagttccat gaagcatcca ttttctcata
     3061 agagaaacgc acgtcttgtc ctggcgcaga accgtttgaa aggaaccatc gaagggcatc
     3121 ggcaccgtat ttctcgataa catccattgg gtcaatcccg ttaccgagag acttagacat
     3181 cttgcgtcct tgctcgtcac gaataagacc gtggataagg acgttttgga atggttgacg
     3241 gcctgtgaat tccaatgact ggaagatcat acgagacacc cagaagaaga tgatgtcgta
     3301 acctgttacc aaggttgaag ttgggaaata acgtttaaag tcttctgagt cgacttcagg
     3361 ccagcccatg gttgaaaatg gccagagggc agaactgaac caagtatcca agacgtcttc
     3421 gtcctgagtc catccgtcac cttctggagc ttcttcgccg acatacattt caccatcagc
     3481 attgtaccag gcagggattt ggtgacccca ccaaagctga cgagagataa cccagtcgtg
     3541 gacattttcc atccattgaa ggaaggtatc gttgaaacga ggtgggtaga attcgacctt
     3601 gtcctctgtg tcttggttgg caatggcgtt cttagccaat tggtccatct tgacgaacca
     3661 ttgagtagac aagcgtggct caactacgac acctgtacgt tctgagtgac caacactgtg
     3721 gacacgtttt tcgattttga caagggcacc gatttcttcc aacttagcaa cgactgcctt
     3781 acgagcttca aaacgatcca tgcctgaaaa ttcaaaggca agctcattca tagttccgtc
     3841 gtcgttcatg acgttgactt gtggcaagtt atgacgttgg ccaaccaaga agtcatttgg
     3901 atcgtgggca ggtgtgattt tcacgacacc agtaccaaac tcaggatctg cgtgctcatc
     3961 tccaacgatt gggatgagtt tattagcgat tggaaggatg acgtttttac caatcaagtc
     4021 cttgtagcgc gggtcttctg gattaaccgc aaccgcaacg tccccaaaca tggtctcagg
     4081 acgagttgta gcaacttcaa gggcgcgtga accatcttcc agcatgtaat tcatgtggta
     4141 gaaggcacct tctacatcct tgtgaatcac ctcaatatca gaaagggctg tgcgagctgc
     4201 tgggtcccag ttgatgataa actcaccacg gtagatccag cctttcttgt aaaggtccac
     4261 aaagacctta cgaacagctt ttgacaaacc ttcgtcaaga gtgaaacgct cacgagagta
     4321 gtctacagag agccccatct tgccccattg ttccttgata gtagtggcat attcgtcttt
     4381 ccattcccag actttcgtca agaaagactc acgaccaagg tcatagcggg aaatgccctc
     4441 accacgcaag cgctcctcta ccttagcctg agtggcaatc cctgcgtggt ccatcccagg
     4501 aagccaaagg gtatcaaaac cttgcatgcg tttttgacgg atgataatat cttgcaaagt
     4561 tgtatcccaa gcgtgaccaa ggtgaagttt acctgtaacg tttggtggtg gaataacgat
     4621 tgaataaggc ttagcctttt gatcgcctga aggcttgaaa acatcagcat caagccattt
     4681 ttggtaacga ccagcctcaa cctcggctgg attgtattta gatgaaagtt ctttagacat
     4741 gtgtgtgtcc tttctctatt ttgtttattt tattttgaat ttgcttagca gcttcttctg
     4801 cagacaaatt cgtattattt attttaaagt agtggtgcaa ctcattcggt tgatattggg
     4861 aatttaattg aagtgtttca gcggtctcta taatttctct ttcagatacc tcaatatgtc
     4921 gttttaaggg tttgtacttt aatcgattct ccgttcgatt tcgacgtatg cactcttcaa
     4981 gacttgtttc caactcaaca aaaagaatct cttgatgata atcatccaac aaactctgaa
     5041 tttgctttaa atatatcaga tgatactgat ttgaaaaatc aattacatct gttaaaatta
     5101 ctgatcgctg atttcttgca ctcgctccaa ggaatgaaaa agtgattcca cgaacaaatt
     5161 cccacatttc ctctgtatag tcctgataga tttctagtgc aaaatcgatg gcttgatggt
     5221 tataaaatag ggtagcatcc gtcagtcgag ataattcttg accaatggtc atttttcctg
     5281 atgctggagc accaatgatg aaaagatgca tcaaatcacc tcccattcac tcttcagcaa
     5341 ggcatatctt aaatcatcac agcagttgcc ttgagcatct ttgcggtctc ttatgcgagc
     5401 ttcgagggta aagccaagct tttccgcgac tcgttgactt tgaaggttat atccaaagca
     5461 agttagttca atcttgtgaa gacccaaatc tttaaaggct aagtcaatca aggcacgcgc
     5521 agcttctggc acataacctc gcccccaata gtctgagtgt aaggtatagc cgatttccat
     5581 cacatcatct tcatggcgat ggttgaaata gatagagcca acgatcttat ccgttccttt
     5641 gacgacaatc ccgtagcctg ctgggagatt ttccttttga ttacgctccg gaagaatgtg
     5701 ctccagataa taaatctcat cttccaagat cttgactgga ggaaaacctg ctggataggc
     5761 gacctctggc aaactagcat agtcaaagat atcctcagca tccgccacag tacggactcg
     5821 taaaacgaga cgttctgttt cgattttatc tggcagctca gttcttgcca tccttcttcc
     5881 tcgctttttt gatgaaactg cccttcatat ctacacgctt gtccagatag cgataaacgc
     5941 gctgatatcc atctcccatg aaataggttg gggcaaacag ttgattttta aaatgtccct
     6001 tttcatccag gagttctggg gcaacaagtc gctcaagaat cttggcaaag atgtggcaaa
     6061 taccgtcttc ctcaacaatc ctatctaccc gacaatctaa aacaagtgga caggcgtcta
     6121 aaataggaat ctgagttcgt tcagaaattt cataatgcac tcccaaacgt tccaatttct
     6181 cctgatgact gataaaacca gcctgctcca tcgcaagcat agaagtttca tcagaaatat
     6241 tcacagtaaa tttttgatac tgtttgatct gctctgcggc attctctctc gcaacgactc
     6301 caatcacaac ccaatctcct agactataag aggaactaca ggtcgtgatg ttatagccaa
     6361 aattctaatc ttgatatcct aaaataaaaa caggaaaacc ataatatagt ttacttgtgt
     6421 taaaagattg cttcataaca acctcctttg actaagacac aaaagaaaag ccctgccatc
     6481 tacatgacag ggacgaatgt gtttatccgc ggtaccaccc aatttcgggc caagcccgca
     6541 tctttagtct ttaaaataaa aagacagaaa tatttcattt tttcagtcat tagcaaccag
     6601 ttttgacaca tttgtggact tctcagcgcc gccactttct gtaaaatgtg ggattcaaaa
     6661 cacctctaat ggctctattg tagcaagatt ttttcggaaa tgcaaggctc aagaaaaatt
     6721 acttgaactt gatgccattt tctttcaatt tcttgatggt agctggaccg attcctttca
     6781 agtcaaggag ttctttttca gtccagtttt tgaaatctga agcagacttg attccttcat
     6841 catagaaagt cttggcacga tcaagtggaa gtccacccaa gtttgctgca aaatcttcta
     6901 cagaattagc tactttttga gcttgctctt tggtagcttc tactgcttgt tcaacttttt
     6961 tagaaacagc cttaccagct gcgcttgctg actgttctgc acgcttcacg actttttttg
     7021 tctcatctac aaccttagtc accgtacttg aaaaggcacc tgcgcgacgg aggccatttc
     7081 gtaattgttt tttacgattg agtttctttg acatgataaa atcctttcaa taaaaaatcc
     7141 ctgctctgac aaggatttaa cataaacatt ctatcaagat tttagtgaaa aatcaagaat
     7201 ctttctcgtt taataatttc gctcaccaaa caagccttct ggcaaatcat ggaatccctt
     7261 gcctgctttg aagttttcaa acttaccaag caagaactga taagcatcca agcgactctc
     7321 gtagcgaatc atggcatctt tggcacgctc gtcctggtct tcttcgtaaa ctttttgact
     7381 ttccttgtgc gccatatcgt taatcatgat ttgggtattg acccaagctt caaattcctt
     7441 cataaattct tgttcgtaac tcattttttc tccttattct aatccacgaa aatagtccgt
     7501 atcaatctca cggtagggct ggatatcctg aacatactcc aacactcctt ggaattctcc
     7561 gtcttcatcg tgtactgcag cataggtgat gtggacaaac ttacctcgcg actcagactt
     7621 gaaccacatt tcatacttgt ctttgcttcc ctcacgaagc cccttcatga tagttttgac
     7681 cttgtccaag tacttaggcg gatggcagag ttcgacattg cgcccgactt gagacggcgt
     7741 ccgtttgaaa atcatctcat cagctggcgt attgtcattg taatactgga aaatatcatc
     7801 tttattgaca aaggtaatct ccatagggag gtgattgagg atgagattgg cctgctcgac
     7861 tgaaagatag ccattaccaa aagcctgttg actatggcgg tccagcacag cttccttttc
     7921 cttaggggta aaggtaatgg taaaatggcc ttctggcgta tctatgactt gttgaacttg
     7981 accttctgcc gtatctagct gtacaggctc ctctgcaatc ttttcctcaa taaagctctg
     8041 tcgttctggc acccatttct ctgacggacg gatgatggca tagccatagg catcgctctc
     8101 ctccgcaatc tgaagccagt catcctgagt aaaagactca aggagaatca tgaggaggat
     8161 ggactcttcc ttgaaaatca tactttcaaa ctctgtcgca aaagcttcaa aagcttcctt
     8221 tacactgcta attgacactt ctggtagtga cttggctgtc gttagagctg tttgaaagag
     8281 ttccctaatc tgatcatcca ctccccacat aactttggga ggtgaatcgt gtccatagcg
     8341 ctccatgata ggaaagaaga gttcttcctt acgttggtaa tggatgtcaa attgacccac
     8401 aagtcccatc tgacgcacca aacccttacg catctccgcc agcatttcct cgtcttccat
     8461 agactcatag gtatctaaca atctacgaat gcgaatcaag gccgcacgga gagccagatt
     8521 ttcttctttg aagacacgaa ctgggtgacc tggatgctca gtatctgaaa cttcgacacc
     8581 tttgatagca tttttaaaaa gattggcatg gacatcacag agttccataa catcttcaaa
     8641 agtgacgccc gaatccgagt tcatcagctc gtgctccata agggaaatct cgatggctga
     8701 cacgcccgta aaggtcgcat caaagcgatc ttgaaccgac tcaggagagg cgccattgtg
     8761 caattctaac aaaatatccc gtaggatatg aatccgttca tctgtcatta gtctaatcca
     8821 atcacttcgt agccattcgc ttccagtgtg cgtacaatct tgtccatagg agttcctgct
     8881 agcttagaac cctgtttaag tgatacttta cgaccaactg tattgcgcat taagggattg
     8941 gcaaggggtt taaaacccaa ctccactaga atttccaaga cttctggatg cttgtccacc
     9001 acttctgcaa caggaattga cacatcgatg atattgtcca tgacgacctc cattgtatgt
     9061 tctaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac
     9121 agtgttttga ggttgtagat agaactgacg aagtcagctc aaaacaccgt tttgaggttg
     9181 tggatagaac tgacgaagtc agtaacatat atactgcaag gtgaagctga cgtggtttga
     9241 agagattttc gaagagtata aaatgatttt actgcttata ttataccata tggaaagaga
     9301 ataaaaaact agcagtggag ttcctgctag ttctctgcaa cttggattac catctagata
     9361 agtttaaaga gccaatccaa tatcttaaac actatcttgt aaaacagcaa ttggactgca
     9421 aaagagatga tcatccaaaa gaatttcaca atcccaataa tcggtttgat aaaaagaata
     9481 gcaagaagac caaaaaaatt tcattctctc tcctctggct taatgagcca ccgagccgta
     9541 tccattaact tgtcggcaat aaaaagtttc cccagaccaa caacgacatg gtcagctttc
     9601 tttatcgttt tcatcacttt tacaccttgc acggtcaaaa agtaattacc ataaatttta
     9661 gcaaaagctt tgataggatt catattactc tcctttgatg atttcagcct cttttcggat
     9721 tgtttcaaca tcttcttgat attgaacttc actatagttg actagcttgg ataattcttt
     9781 ctgcaagctt tcccccattg gtttcatagt tgcaaaggtt aaaccacctg aaatgatacc
     9841 acccaagata ggaataaatt tccctattcc tttggccagc cctcccttgg taagattcac
     9901 accaaatatt cttaagactt ttttcaaaat agggtaccaa agcgtctttg ttaaagcttt
     9961 attaggcact gttttcatta cctgtttggc aattgttata ccaccagcac gtagcaaagc
    10021 agcggttcca ttcaccccta acattacgcc tagataaagc aagagggtat tttgagcatc
    10081 ttcactcaac tcctcgcgtg aagcccaaag atcctcataa ccataaatat aacctaattc
    10141 ttgagccaat ttcagagaga aagcataaaa ttgagccaca tcagctggaa tggtaattgc
    10201 catagcaagc cctccagcta atcctgccaa aacagaagtc ccactcgcta ataatacatt
    10261 gtcccgaata caagcattag ctacacgatc taatatttct tgagatagaa gagtcgttgt
    10321 accttgttcc aataaggtag gaatatcttt tggatccaat tctttggaaa acttatccac
    10381 taaaaatttc gaacgatcaa ccttaacaac aggtagtttc accacttgtt gcaatacttg
    10441 catagctaag tcttgttcag ccatatacaa actccttatt tcttttttac accttatcat
    10501 attatatttc ctacaaaaaa agcattttct aattagataa cattaaaaaa tacagaatcc
    10561 cttttttata ttaaaacgaa acaagaacag gacaaatcga tcaggacagt caaatcgatt
    10621 tctaacaata ttttagaagt agaggcgtac tattctagtt tcaatctatt ataaaagaat
    10681 atttttccat ttcaaattca acctattttc ctccaccaaa aaagaggggc aacccctctt
    10741 ctttagttct tatccagatt gcgtagcatc tcgtcaatct tgtttccata ctcgatggac
    10801 tcgtctttga cgaaggtcaa atctgggatt ttgtacaatt tcaaattgcg accaagttca
    10861 cgtttgatgg taccagttgc tttttcaagc ccgatttgga ctttttggtt atccgaagca
    10921 aggttactca aaatggtgta ataaaccttg gcaacagaca agtcacccag catctgaaca
    10981 tctgtgatgg tcacaccttg gacacgtgga tcacggactt tcttttgcaa aatctcattg
    11041 acttcacgct tgatttccat gcccacacga tctgtacgga aatgatttgc catgatattc
    11101 ctttctctac tttgaaccaa aagctaggcc agcagaccta gctattttaa acttcttgat
    11161 tttcagttta aattgaaacg aagttcaatt tgaagtcatc tgcttctttc gccgtggtga
    11221 aagtgatgga actgatttat cagtcccatc acaggggatt tttgagaccc taggctcaaa
    11281 aataagcaat gaaaccatcg gtttgcttgc gtccctcacc acctaagaaa ggagcaaaaa
    11341 atcttatctc ttgatttctt ccatgacata cgcctcaatc acatcatcca tcttaatatc
    11401 attgtagccg tcgatcatca atccaccttc acggccgttt gtaacttcct taacgtcgtc
    11461 tttatagtgt ttcaagcttg cgagttcacc atcatagata acgacaccat cacggataac
    11521 acggacttta gagtcacggg caaccttacc gttgataacc ataaatccac cgatagttcc
    11581 cactttagac accttgaagg tttcacggat aaccgcttca ccaataactt tttcttcaaa
    11641 ttctggatca agcatccctt tcatagcttc ttccatctct tcgataacct tgtagataat
    11701 gctgtgaaga cggatttcca catcgtcagc ttctgcttgt tgacgagctt gtggtgtagg
    11761 gcgtacgttg aaaccaacga taaaggcatt tgaagcttcg gcaagggtca cgtctgattc
    11821 gttgatagca ccgaccgctg agtggacgat agtcactttg acaccttcca cgtcaatctt
    11881 ttgaagtgag gcagaaaggg cttcaacaga accttgtaca tcagccttga tgataacatt
    11941 aacagatttg agttccccag ctttaagggt atcaaagagg ttttcaaggc taacacgttg
    12001 ggtagcttga cgttgtttca tgagggcacg tttggcacgc tcttcacctg ctgcacgcgc
    12061 agatttttca tcctcgtaaa cggcaaagtg gtcacccgcc atcggtgctt cgttcaaacc
    12121 tgtgatagag actggtgttg atggtccagc aactttaaca cgacgaccaa ggtcgttggt
    12181 catagcacgg acacgaccga aggtatttcc gacaacgatt gggtcttgaa cattcaaggt
    12241 accttgttgt acaagaaggg ttgcgaccgc accttttcct ttatccaagc gcgcttcgat
    12301 aaccgtaccg attgcacgca ctgttgggtc tgccttaagt tcttggattt cagctacaag
    12361 aaggactgtt tccaacaatt cttcgatatt ttggttgaat ttagctgaga tttcaacaaa
    12421 ttcagaatct ccaccccaag cggttgacat cacaccatgc tctgccaatt caccgataac
    12481 gcgttctggg ttagcacctg gtttatcaat cttgttaatg gctacgatga ttggaacgtt
    12541 ggccgctttt gagtggttaa tggcttcgat agtctgaggc ataaccccgt catctgccgc
    12601 tacgaccaag atcgtaatat cggtaacaga agcaccacgc gcacgcattg atgtaaaggc
    12661 cgcgtgtcct ggtgtatcaa ggaaggtaat cttcttacca ttttccacga tttggtaggc
    12721 accgatatgc tgagtaatac cacctgcttc acctgtcgca acacgtgagt tacgaagagt
    12781 atccaaaagg gttgttttac cgtggtcaac gtgtcccatg atagtaacaa ctggtggacg
    12841 ctcaaccaat tcatcttcat tgagataacc atcttcgaca aagaaacgtt cgatgtcagc
    12901 attatccact tcaacctttt gtttggcttc gataccgtaa tccaccatga ggagttcaat
    12961 tgtttcccca tccaaggatt ggttttgtgt ggccatgaca cccatcatga aaagtttctt
    13021 aacgatttca gctggttcac gtttgatacg ttttgcgatt tccgcaacgg tcataccatc
    13081 tgtatattca aattctgttg gcaattcatg gaatttacgc tccgtaacag gttttggagt
    13141 ctgattacgg ttgttcttgt tattgccttt tttgttcttt ttgttgttat tccagttact
    13201 attcttttga tttctcactt gattttgact acttcgattc ttttgttgtt ttctaggacc
    13261 atcttcttca tgatcataat cgtcacgatt tttgtctggt cgagcttgtt ttttacgacg
    13321 tgtatccact gcaggttctt ttttctcagg gacgacttca accactgctt gaacttgctg
    13381 tgcttgttca gctaacttag ccgcttcttc aaagatttcc tctggttcct tgcgtttgtt
    13441 agcttgagcc aaggcttctt tagcagcctg atactgcttg aagcgttcct cacttgaacg
    13501 agcgtactct gcattttgct ctgcttttag ggctgctgca cgggctttaa agtcaatacg
    13561 tggagccact tgatttgaac gtttgtcctc ttgctgacgg cgctcatttc tacgtttttg
    13621 ctgaccttgc tgcttcttag cttggtcatt aaagcgacga ttgtcgcggt tgctttgacc
    13681 ttgttttcca ccattacggc cgtcgttttt ctgacggttt ccgttttgtt gttggtcacg
    13741 gttattgccc ttattttgct tgcgtcgttc tgcctgctct ttagcacggg cttcacgctc
    13801 agccttgaaa ttacggcttt gcggtttcgc tgctactttt tctgttttcg gagcaactgg
    13861 ctcagccggt tttgcctctt ccttagctac agctggttta gctggctcag atttttcggc
    13921 tttcttttct gcacttactt ttggtgctgc aggttttgct tctactttcg gagcagctgc
    13981 aggcttaaag ctggcagcaa tttttgcagc gacagcttct tccacacttg atgagtggct
    14041 tttcacatcc aagcccaact cttttgcacg cgctacaact tctttacttt cttttccaag
    14101 ttcttttgcg atttcgtaca atcttttctt agacaaatca tgtcctcctc ttctattcca
    14161 taagagacct cattttcttt gtaaatccag catctgttac agccaaaacc tttctcgatt
    14221 tcccgactgc tatgcttaat tccagtgttg aaaacacggt tacaatttct acttgataat
    14281 aatgactttt atcttgaatc ttcttggtca gattgggtcc agcatcatga gctagaaaga
    14341 ccaacttggc cttgccgtct tgaatggcct tgaccaccaa ttcttcaccc gatatgatgc
    14401 gccctgctcg ctgagcaagc cccaagagat tacttatctt ttgcttattc aagtcccaac
    14461 tctcttcttt tcactttgtg atccacataa gcgatcaact cgtcataaaa gctttcttcc
    14521 acttccatgc taaaactgcg gttaaagacc ttcttctttt tcgcctctag ggcttctgca
    14581 ttgtctagtt tgatataagc gccgcggcca ttggccttgc ccgtaggatc aataaagact
    14641 tgtccttcct tgttcttgac aatgcggagc aaatcacgct tatcaatcac ttcgttagac
    14701 acaacagact tgcgcaaagg gatttttctt gttttcatct ttccctcctc tagcagcttt
    14761 tattcttcta cagtatcgtt ttctacttcc aactctactg aagcagcgtc ttccatggct
    14821 tcaaattcgc tagcagactt gatatcgata cggtaaccag tcaagtgagc cgccaagcgc
    14881 acgttttgtc cacgacgacc aatggcaaga gaaagcttgt tatctggaac aaccaccaag
    14941 gcacgtttgc tgtcgttttc atcaaagata acttggtcaa cctcagcagg agcgatggca
    15001 ttgtagataa attcagctgg atctgctacc cactcgataa catcgatatt ttcttcgatt
    15061 ggtaccatgc gatcattttt agcatcgtaa cgatctgggt ggaatttgct agtaatcttc
    15121 ttgatattag caccaccacg tccaacgatt gtaccgatag catccacgtt tggattgtgg
    15181 ctacgaacag caaccttcgt acggtcacct gcttcacgag ccacgctcat gatttcaaca
    15241 gttccatcat aaacttctgg aatttcttgc tccatcaaac gtttgatcat ttctggatgg
    15301 ctacggctaa caaagacgtt cacaccacga gggttgtctt caaccttgta aacataaact
    15361 tcgatacgat catgagaagc aaaaacttct ccaggaattt ggtcttgttt tgacaattgg
    15421 gcttcgatgc taccaaggtt gacatagata aagcggttgt caaagcgttc tactgtacca
    15481 gacatgattt cttgctcatg ttctttgtaa gtattgtaag tgatggcacg tgtttgcttg
    15541 cgcatttttt ccatgatggt ttgtttggca gattgggctg ctacacgacc aaactcagct
    15601 ggtgcttctt caaacttgat tttgtctcca agttcataag ctgaattaat ggcaagagca
    15661 tctttcaagc tgatttccaa acggctatca aatacttcat caacaacttc acggacagta
    15721 taaactgtaa agtcacctgt tttttcgttg aagtcaatag ctacgctgtc tgactgacca
    15781 tagcgtctgc gataagcgga acgaagcgac tctactactg cgtcgatgat gtcttctttt
    15841 ttgattccct tgtcttcttc caaaatgcgg aaggcctcta gcatttcttt actcatgttt
    15901 tcttcacttt tgaatcctca aaagctatcc tttctttttc tataatttaa ctgctaaacg
    15961 tgcttttgat actaaactgt atggaatttg gacggttttc ttacgcgtct tgtccatata
    16021 ttccatagtc aactcgtcct cttcgaaggc caacaaggtt ccttcaaaga ccttttgctt
    16081 atcgatggct tggtagagcc cgacatggat gtattttcca accgctccag cgacggcatc
    16141 cttggttttc aaaggacgtt ccaagcctgg actggtaatt tctaggaaat attgttctgg
    16201 gaagggatct ggcttgatgg tgtctaggac aggactgatc atttctgtta agtctgccgt
    16261 gtcgttcaag gtaattcctt cggttttatc tacaaaaata ctgagaatca tgtcactgcc
    16321 aatctttcca tactcgatat ccacgagttc aaaaggagct tctatgacag gttctacaac
    16381 ttctctgact aattctacga ttgttgcgat tgcgtccacc tcctcataag caagaggcga
    16441 agatatttcc ccgcctcact tttcatattc ttaccatcag tatagcacgt ttgccaactt
    16501 atgtaaagca aaagcacttg tacagcctaa ttttaggcta tctcttaaaa ttctgcctca
    16561 actcggtaga taacttgccc cttgtttgag aatttttgct cgtattctgt catgacattg
    16621 ccttcaaaat cactggcatg caaatctagc cagacaccat tgagtttcat gccatattga
    16681 gaaaagctca ctaaactgta ctcaaacaag ccacggttat ccgtcttgaa atgaatttct
    16741 ccattttcag gcaagatacg tttgaaggta tccaaaaagg tcttgtaggt caaacgacgc
    16801 ttttcatggc gttttttcgg ccatggatct gaaaagttca gatacaagcg atcaatctca
    16861 ccgtcttcaa agtagtcagt caagtcagaa ccatctaccc acaagagctt gatgttagac
    16921 actccagctt caagcacctt gtccaaagcg tagctcaaaa cagacttttg aatatcaatc
    16981 ccgatatagt tgatgtcagg gttttgcttg gccatacctg aaacaaaggc accctttcca
    17041 cttccaactt ccacatgaat gggattatca ttgccaaaca agtcccgcca ttttgccttg
    17101 gcttccaagg gattgaggac cacatactgg ggatttgcct ctagtaattc tgttgcccct
    17161 ttacgatttc taactctcat cttctctttc catacttgtc tcggaaatga cgcaaaccat
    17221 gaatctcccg attgacattt tctaaatctt ggttcatata atacttggaa atctgactca
    17281 aataagacaa ttgaccatac caatacaatt tacttaatac cgtttgattg tacttgtaac
    17341 cgtagtaggt caaccattcc ttccactgat gttctgaaat ataatggcag agcatatggg
    17401 ccacatcaaa catgcgatcg gtcaagcgaa ccgaatccca atctactaaa taaatcaagc
    17461 cactatctgt ctcaatccaa ttactatgtc gtacatctcc atggacaatg gtcgcatggt
    17521 cctctctaaa tcctggaata gtctgacgta aatcagccat cacttcactg ataaaatgat
    17581 ttttacgcaa agcatctgga gccgtttcct gccaagactg tagtaaatct acaggtgttt
    17641 ccatggcata gcccaaacga ctcaattgtg tcatcaacgg acgtgagcga tgaagacggg
    17701 ttaaaatatt gacgatttgc ttacgattca tatcataggg ggtcaatatc ttgcctgtca
    17761 accattcttg agcacacata tcacgcccat ctgccaaacg acgactccat aataattgtg
    17821 gagcaatttg ttctctagct agaccaggta ggattggaga ggtgttcatt tttacaaaga
    17881 tgcgcttccc atcaggatag ctacccatat aagccttgcc acttttccca ggtatgggag
    17941 tcagtgttag ctcattatca cccaaatcca tttctttcct ccgtataaag tttccttact
    18001 attctactag tttttggcct attcgtcaac cactctaacc cgattctcaa agaaaagcct
    18061 ctggattggc ttgggtatca ttatagcttg aaaaaggtaa gcaccgtctt ctgcttacct
    18121 tttcataatt tttataaata atataagagt ggccaactgt tgtaaaacat gtggactaga
    18181 gtagaaaccc ataagttttg gctcttttta taagcaaggc ccagcaacaa gcccccaagt
    18241 agataaaaaa taaacgaagg gacattagaa ggtccatgca tgaaagaaaa gagagaggaa
    18301 gttagcacaa gccctaacca agaattgtca aaaaccgcac cttgaagaag tcctctgaaa
    18361 atgagttcct cctggatggg gccaaaaact gaggtagtta aaatcaaaga cagggaaatt
    18421 cctctgctga cttccgccaa gtgttggacc cctgagccag aagaaacagc gaagaaatga
    18481 atataaacca gcgtctcaag tacacttaga agaaagattg caatgaaaag caaaagttgt
    18541 ttcttgctta acatcccaaa agaaatcatt tcaaactttc tagcataagc aacactcagc
    18601 gaggttacaa gaagacttac aagaatcaat gcagattcat tttgaaaaaa aaccccatgg
    18661 ttaatcgtat aaggaactgt aatgacaatt attagtacta aaaatccaaa acacaaggca
    18721 tgaaatttat caaaaaactc cataaaatta tcctcctcaa caaacagact tcctacacgt
    18781 cattctttag atctagcctt tccaaaacaa accattttag caaccaaaat ccgaccacat
    18841 agccagcccc tatgaatata gccattaaag ctagcatgga atttaggaaa ttaaaaacca
    18901 ccgcagatac aaaggttagc acaaaaacat taaaagcaat ggtgtcagaa gccaagacta
    18961 gaatataggg tgtcaaccga tctaaagttt tggaatctag gaaaaataag tgtttataca
    19021 tgatgacctc ctctatggct gaaaagcaag ccttttgttt ttttacccca agaccctatg
    19081 tagaaaagtg agcaaaaacg ggaaggtcgc tacaatatta ttgatcacat gcaccgcata
    19141 ggatggataa atgctcttgg tatagcgggt caaaccagca aagatgattc caactgttgc
    19201 aaagacgaag atatctaaca gactaggcag gcttgaaaaa tgagggagag caaataaaat
    19261 agaaggaaga agcaaatcaa gaccaaatcg cgaatgctta aagaaagcat gttgcagtaa
    19321 tcctctataa atcaattctt ccatcagtgg aaccagaaag aacagggcta tataaatacc
    19381 tagctctgca aagttagtcc cactataacc aatcaataca gcccaacctt ccgcagttga
    19441 ctgaacatgt ttagctgtct gaacgttaaa agagatctgg aacactacca ctaatactgt
    19501 caaaatcgaa taccaaagcc atttttttct tggaatgcgg aagagataac catggcctgt
    19561 cttaacaaga accacaatca tgactccaat aaaaagtaaa ctcaagatat tttgaatcca
    19621 gaataaattg cctatctgag aagaaaattg ccaatagttt tggacgataa gcgtcagctg
    19681 agaaagacca aatacgaaaa ataggtagga taaaattgca cttgttttga atagaagctg
    19741 atactttttc atagaaattc ttcctcattt cttatatttc agcctatatt ccacataaat
    19801 gaaaacctgc tcctatataa ccaaggtcac gataaccacg cgggcagtac ccacttactg
    19861 ggaaaggatc tgaatttttt aatatagaag ggtaaggacc aaatggactg tcctgataag
    19921 cataccctct ataaatacca gatacatccc caccctctat acaagcaagc atttcagtat
    19981 ccataatttc aaattgttcc atcatttttg tatccatgac aaatactcct ttttttattt
    20041 ttaatttttt gtcctgttac aactttgaca agtttagtat atcatcgttt attaattttt
    20101 ttcatccaaa tcttgaattg tcatcgaaac gtcttgaatt gttaaaaaat ttaaaaagca
    20161 agcattaaaa acatacttgc cctttcactc ttgtctatag gaaaattcta gccatatgtt
    20221 attacaaaca aataatatca ttgcacctgt ttaccatcta tttttattta tgaattcttt
    20281 gtctccactt aatcatacct gaagtaatta agagtgcaac cgctagacgt aatagattgt
    20341 aactttcttc cactcctgta ttaggtagta attgtttact caaatgactg gttttggagg
    20401 gaaaatcatt cccctcaacc ttggataaag gagtttgtaa cttctcagta ttttcagaaa
    20461 tcgtctgaga tgactcccct cgcttcttct tatctatcat taccaaatct tcagactgaa
    20521 cagttatagt gttagaagga ggaatattat ccttcaatgg ctctctgtta tcactgttat
    20581 tagtcgaatt ttcctttgaa ttcttcacct ctcctgtttt atcatcacgg acactttcag
    20641 ttactgtttc ctcagaagat ttcactgtct ccgtttgctt aggtgagttt ctcgaataca
    20701 tataatcata cacctgttgt gcagttgctc cgtcaccaac ccatccagat gtcggatgtc
    20761 catttcttaa atacaaaatt gttggtgttc ctggaatacc gactttttta aaatagaaac
    20821 tctctcgctt ccccatcaaa atccttacca tccaaatcat aatactctaa cttcttttca
    20881 atcaagttat taaattcttt caattcagga gaaaattgac gacaatgaga gcaagttttt
    20941 ctaccaaaat aaatagtatg ttccaattga tcccctgtaa aagattgacg aacagcttca
    21001 atatctatct ttttaaagtc cgtaacattc ttctcatact cttctggggt tacaacagaa
    21061 ggcttatgct ccaccttttc cttagccgat ggcaaatctg gcgccacaag agaactatta
    21121 ttcgcctggg tagatgaagt aataggctgt tcttctgcat atgcaagacc tgcagtaata
    21181 gatgcaaata caagtggtac aagtaatagc gattttatct tttgtttctt cataagaata
    21241 ctcctttaca tttgttatct ttatcttacc ttatttaaga ttacaaattc atctaaatct
    21301 taaatggtca tcgaaacatc ttgaattgca aaaacttcat tataaaaggg taagtatttc
    21361 aaaaacactt acccctttat actttattaa gctctacttt ttataatact tcaagcccca
    21421 aatgagaaaa agtataataa tcaagcagag aatagcacca atgtaggcaa ttatttgttg
    21481 gtaggattct cctgctgtga tccctctata caaacaaata atagacataa aacctgtcaa
    21541 gccgatgaac atgatttgat tagttctagg actaaccaaa tcatcgtctt caaactcttt
    21601 tatccgcatt tccctagtga ggtaaacagt gaccaaaata gaagctaagt taataaccac
    21661 taaaagaaat tggaaaactg acgaaataga aatagataag tagaaacaag caaaggcaac
    21721 tgacccagga acaatctcac aaagaatatg attcttttta atcaagaaaa tctttcattt
    21781 cttttctttc tttctaatta aagaaaaata gatcataacc gcaatcatat aggctatggt
    21841 ataaaataga ttataccaaa tactctccct aagcggataa agaaagatgg acatgatcag
    21901 atacagaacg aaaataatca gtattttttt cttcataaga tttcctccta aatgtgcgat
    21961 ttatcttagt tgagcaagaa catttacact gctagtatag cacttatttt gaccttggat
    22021 cactcaaatc ataaatggtc atcaaaacct cttgaattgt aaaaattaaa aaaagcaagc
    22081 atgaaaaaca tactttcctc tttatattgt attgatacca acttgtttgt agacttttca
    22141 tcctgctatc acatatcatt ttgacaggcg aaacaatatt caagaaactc ccctgtaaat
    22201 taagctagca aatacagggg agaaatttat tttttagggg gtactatccg tatccttttt
    22261 ggaagatttt gaaaatattt ttctaattaa gtcatccata taaggaccaa atataccaac
    22321 tactaaacca ataataaaac ttttaaaatc cataattacc accaacatgt tgctacatag
    22381 gctacacctc caagtatagc tccacctgca gcaccagtta cacctattcc tatagcaaat
    22441 ggtcccaata gaaatgtcaa accgttgttg cacacccatc aattgcgcca tatgcaaccc
    22501 ctgctgcaca actaattttt cttccccaat caatatctcc accttcaacg caagcaagca
    22561 tttcattatc cataacagaa aattgtgaca tcatttttgt attcatatag tatgtcactt
    22621 ttcagttacg gaacaagttt aatataaaaa ttatcaaaaa aacataggca ataaagagaa
    22681 aaattaattt atcatagatt agaaataata tgacaaaaca attcaatgat gttaattcaa
    22741 tagtcttttg ttttttatca gagatactta tggatagata aataagatag gtttgaaaag
    22801 cgaagagaat aataaagaat atagccttca taaaatttag ctttcatttt tatgatgtag
    22861 cggtataggc taaatatcca caaaccactg ctcctccaat tcctcctatt gcagcgcccc
    22921 atggtcctag aattttccca tatttcactc cacccgcagc accagttgct gcaccttgcc
    22981 atgttcctgt tttaatgcct agttgaagac ctcttgctgc tgctcctcca acacctgctt
    23041 tggcaaaatc tccccaattg catccgccac cttcaacgca agcaagcatt tcagtatcca
    23101 taacagaaaa ttgtgacatc atttttgtac ccatgacaaa tactcctttt ttaaaaaact
    23161 aaaataaatc agaatagaat cctcataatt ttactataag tcttaccaac ttagtcccaa
    23221 tttatcacca accatacctc ctaagcatgt taatccatcc ccaattgcac caatgtgtgc
    23281 tccaacaaat gcaccaacaa gtccagctac tcctaaagtg gccaaacctg ctccagttcc
    23341 accagttata attcccgtag tgactcctgt aatcagtgca ttttgacaat cagtggagct
    23401 atacccccct tcaactttcg caagcatttc agtatccata acctctaact gtgacaacat
    23461 ttttgtattc atgatgaata cctccttttt attttcaatt tgttaccaaa gtcttaaatt
    23521 caataaacaa atagattttt tatagtatct ttttgatttt cttaaaaaag tatatacgtc
    23581 tactatcttc ttaaaggtag cagtacctat tttttagtct aagatttcaa taatcttgag
    23641 tatctaaaat atcttaattt cgttattctc cttgcaataa aaagttttac tatactattt
    23701 attaacttgc agaaagcaaa aaatattagt aaataatagt ttatagttaa gttttttatt
    23761 cctaccaatc catcaactaa gtaaagcatc aacgattaca taaacgattg ataatataat
    23821 taaaatttta ctaactatct tattctcatc attcttagat aactttgata ttttgtaagt
    23881 aagtaaataa gacagtaaat taatagcgat aataatacta tatttaagaa tcataatctt
    23941 acaaagagga cataattcct gaacctacac aaataagtgt tgctgctccc ccagttatcg
    24001 gaccagtcgc agcagctaat agtactgctc caatacaacc accgattgca gatcctaaat
    24061 tgcctcttcc tccactaact atttcgagtt cttcattatc cataacagaa aattgttcca
    24121 tcatttttgt attcatgaca aatactcctt ttttattttt tatttttgtc ttgttgtaac
    24181 tttgataagt ttagtatatc atcgtttttt aaaatttttc atccagatct tgaattgtca
    24241 tcgaaacgtc ttgaattagc ttttttattt caagccacct ctaaatgttt aaaaaaaata
    24301 atttctaatc acttttttac cattcaggaa gttttaatga ctattcaaga tttcataaaa
    24361 tatgaactta gttttatgac ataatagacc tatccactat atgaaaggaa ttgccaatga
    24421 cttcttataa acgtacattt gttcctcaaa tagatgcgag agactgtggt gtcgctgcct
    24481 tagcctcgat tgctaaattc tatggttcag atttttctct agctcacttg agagaacttg
    24541 caaagaccaa taaagaaggg acgactgctc ttggcattgt aaaagccgct gatgaaatgg
    24601 gctttgaaac aagacctgtt caagcagata aaacgctctt tgacatgagt gatgtcccct
    24661 atccatttat cgttcacgtt aacaaagaag gaaaactcca acattactat gttgtctatc
    24721 aaacaaagaa agactatctg attattggtg atcctgaccc ttctgtaaaa atcactaaaa
    24781 tgtcaaaaga acgctttttc tatgaatgga ctggagtagc tatttttcta gctaccaaac
    24841 ccagctatca accccataaa gataaaaaga atggtctact aagcaagctt ccttcctctg
    24901 attttcaaac aaaaatctct cattgcttac attgttctct caagcttatt ggtcactatt
    24961 atcaatatag gtggttctta ctatctccaa ggaatcttgg atgaatacat tccaaatcag
    25021 atgaaatcaa ctttaggaat catctcagtt ggtctggtta tcacctatat cctccaacaa
    25081 gtcatgagct tctccagaga ttatctccta accgttctga gtcaaagatt aagtattgat
    25141 gtgattttat cctatattcg ccatattttt gaacttccca tgtctttctt tgcgacacgt
    25201 cgtacaggag aaatcatttc acggttcaca gatgctaact ctattataga tgccttggct
    25261 tctaccattc tttctctttt tctggatgtt tctattctga ttcttgtagg gggagtcttg
    25321 ctggcacaaa accctaatct cttccttctt tctcttattt ccattcctat atacatgttc
    25381 atcatctttt cttttatgaa acctttcgaa aaaatgaacc atgatgtcat gcaaagtaat
    25441 tctatggtta gctctgccat tatcgaagat atcaacggga ttgaaactat aaagtcgctc
    25501 acgagtgaag aaaatcgcta tcaaaatata gacagcgaat ttgtagatta tttggaaaaa
    25561 tcctttaagc tcagtaaata ttctatttta caaacgagtt taaagcaggg aacaaaatta
    25621 gttctgaata tccttatcct atggtttggc gctcaattag tcatgtcaag taaaatttct
    25681 atcggtcagc tgattacctt taacacactt ttttcttact ttacaactcc tatggaaaat
    25741 attatcaacc tccaaaccaa actccaatct gcgaaggtcg ctaataaccg tttgaacgaa
    25801 gtctatctag tcgaatctga atttcaagtt caagaaaacc ctgttcattc acattttttg
    25861 atgggcgata ttgaatttga tgacctttct tataagtatg gttttggacg agatacctta
    25921 acagatatta atctcacgat taaacaagga gataaggtta gcctagttgg agttagtggt
    25981 tctggtaaaa caactttagc caaaatgatt gtcaatttct ttgaacccta caaagggcat
    26041 attttcatca atcatcagga tattaaaaac attgataaaa aagtcttgcg ccgtcatatt
    26101 aattacctac cacaacaagc ctatatcttt aatggctcta ttttggaaaa cttaaccttg
    26161 ggcggtaatc atatgattag ccaagaagat attctaaaag cttgtgaatt agctgaaatt
    26221 cgtcaagaca ttgaaagaat gcctatgggc tatcaaactc agctctctga tggagctggt
    26281 ctatcaggag gacaaaagca acgaatcgct ctcgctcgtg ctcttttaac taaagctcct
    26341 gttttaatac tagatgaagc tactagcggt cttgatgtct tgactgagaa aaaggttata
    26401 gataatctta tatccctaac tgataaaacc attctctttg tagcccatcg tctcagtata
    26461 gccgaacaaa ctaaccgtgt cattgttctt gaccagggga aaatcattga agttggtagt
    26521 caccaagagt taatgcaggc gcaaggcttc taccatcatc tattcaataa ataaggagaa
    26581 tgtcatgaat cctaatcttt ttagaagcgt cgagttttat cagagacgtt accataacta
    26641 tgcgacagtg ttaattatac ctctttcatt actgtttact ttcatcttga ttttctccct
    26701 tgttgccaca aaagaaatta ctgttacttc ccaaggagaa atcgccccta caagtgtcat
    26761 tgcatctatt cagtcgacca gtgataatcc tatccttgct aatcatttag tggcaaatca
    26821 agtagttgag aaaggtgact tactcatcaa atactctgaa acaatggaag aaagtcagaa
    26881 aactgcctta gcaactcaat tacaaagact tgagaagcaa aaagaaggac ttggaatttt
    26941 gaaacaaagc ttagaaaaag cgactgatct tttttctggc gaggatgaat ttggctacca
    27001 taataccttt atgaatttta ctaaacaatc ccatgatatt gaactgggta tcacaaagac
    27061 taacactgag gtttcaaatc aagctaatct tgccaatagc agttcatcag ctattgaaca
    27121 agaaattaca aaagttcaac aacaaattgg agaatatcaa gagctgagag atgctatcat
    27181 aaataacaga gcacgcttac caactagcaa tccacaccag tcaattttga atcgttatct
    27241 tgtagcctca caaggacaaa cacaaggaac ggcagaggag ccatttttat ctcaaattaa
    27301 tcaaagtatt gcaggtcttg aatcatctat cgcaagcctc aaaattcagc aagctggtat
    27361 cggaagtgta gcaacttatg ataacagttt agcaaccaaa attgaagtac tccgcactca
    27421 gtttttacag acagcctcac agcaacaact aactgtggag aatcaattaa cagaattaaa
    27481 agtacaacta gatcaagcca cacagcgttt ggaaaacaat accttaacct ccccaagtaa
    27541 aggtatcgtt catctgaaca gcgaatttga aggtaaaaat agaattccaa ctggtacaga
    27601 aattgctcaa atattccctg tcatcacaga tacaagagaa gtactaatca cttactacgt
    27661 atcttctgac tatctacctc tactagataa aggacaaact gtaagattaa aactggagaa
    27721 gattggaaat cacggcacca ccatcatcgg ccaacttcag acaattgatc aaactcctac
    27781 cagaacagag caaggaaatc tctttaaatt aaccgctctt gcaaaactat ctaacgagga
    27841 tagtaaactc atccaatatg gcttacaagg tcgcgtcact agtgtaacta caaagaaaac
    27901 atattttgat tatttcaaag ataaaatttt aacacattct gattaatttt cagataacac
    27961 tctataacta tttattatct tatcaaaaag gagaatcata acatggataa gaaacaaaac
    28021 ctaacttcat ttcaagaact aacaactacc gaactcaacc aaattacagg tggaggattg
    28081 tgggaagatt tattatataa cattaataga tatgctcatt acatcacata agaacttcat
    28141 catccaatac aactataaaa aaataagacc gagaaacaag tactctcggt cttatttttc
    28201 atcattctgt aggtatcata gtaagcacct gacgaaagac ttgatcttga caggtagtat
    28261 ttaaactggc attgggataa ctttccacaa tcttcataac ggtatagaga ccgacacctc
    28321 tctcctcccc tttagaacta actccaaagg agaagatttc agaaatatct atgccctctt
    28381 ctttgatgga attttcgatg atgaaggtct cctgtgctcc actttttaaa aaggcaattg
    28441 aaacatgagg ttgaccggcc tctgcactcg cttcaatagc attatcacaa aggatagaca
    28501 caatggttag aaaatcaagc agtctcatcc cctcaacctg aatctcttca ggaacttcga
    28561 cattaaagac aatgtccttt tctctagctt ttataaattt tccagctagg agacttttga
    28621 gggcacgatc ccgaacattc accaatctgc ccaggtcata tttattgttc tgcaatttct
    28681 gactggaatc ctttaagacg gagccataga cctcttttat ctgctccata tcctcctctt
    28741 caatgcccag acgtaagcta gtcaagaggt tggtataatc atgacgaaag ctccgtactt
    28801 ccttgtaaag ctcctctata tgccgactat agcgttccat atctctatag cgcagggcct
    28861 gctcttgttc caatctctca tagagttttt ccttcaaata ggtatccaat ttcttgataa
    28921 cccccataaa aaagagtagg taaaacacta ggatgagatg gcgaacagtc gttgattgaa
    28981 taccttgctc atattcaaag taagacagac tttgtatcac caaatagtaa gcccccatta
    29041 tccagttaat cttagtcagg gacttttgaa aacctgtatc tagaatctcc cttctcaaac
    29101 tagtaaaatc atagtccaac catttcaaaa aggctagaga aatgaagaaa ttgaaaatta
    29161 ttatacataa cccagtaaat gagtagccat catatacttg ctcttgtccc aaaaatggaa
    29221 gcacaaaata ggagactcct ctataaaaga gattcaccaa tatcattgga aagagaccat
    29281 aaaagaaaag gagtttttta ggaagccctc ttaacaataa gaaagacaag cctatgccgt
    29341 acaagggttc cataaaataa gataggtaaa catttcctac catatagcca atcattacaa
    29401 aaacaaaggc caacagtatc ttcaaaagaa aggccttaaa aatcctctca aaagtgagac
    29461 caattccatc taccttaaag aaaatgacaa tttctagccc attagtaata agtgtataca
    29521 atataatcca aaaaatatac ataaatttcc tagttcagtg taagttatta atagcctcag
    29581 acacttccct gaccttataa cgcgcgatca gacagcttcc accattggga aagaaaagga
    29641 gtttttcttt cttatccaaa tgcaccacat ttgcaggatt gatgagaaaa gagcgatggc
    29701 actgcaagag acggggttcc tgcttaaaaa cctcctctaa actcgccgta aattctagcc
    29761 tgtccgtctt ggtatagaga ataacacgat ggggtcttgg ggatgtttcg agatagtaaa
    29821 cctctttgaa aggatattgg aattgggcaa attttgattt aaagtaaaag caatcttccg
    29881 ccagactttt actatcttga ctattggcat agaggagggc tgtctcgata cgagattcaa
    29941 actcctctgc cgaaagggcc ttatcaatgt agtccaaagc tgacacttgg tagcgaaagg
    30001 acagaggcat aaactccgag tgagtcgtca caaagacgat tagggcataa gggtcccgat
    30061 cccgaatctt tctagccact tccagcccct tcatctcctc atttcgaatc tcaatgtcca
    30121 aaaagaatag ctgatgggcc cccttctcat gcacctctgc cagcagttgg tccggcttgc
    30181 caaatacctc aaaagagcta ggaatgatat gatgtgcttt caaaagtttc tcaatcgtcg
    30241 tttcaattct agtctgttgg gaaaaatcat cttctaaaac aaatattctc atcttcttac
    30301 tctccctctt tcaaccattt ttgacgaatt tctctatagc gacgtctggc atacttgaca
    30361 gcgtattgac cttcttctcc gagaaaaagg attctttctt gaaaatcaat cgattttaat
    30421 ttatcaagat taaccaaaca atttcgatga catctcatca aggtttcccc atattggttc
    30481 tcaagattac ttaaattttg aagcatatta aaactagctt cttctgtaac aatctgtacg
    30541 gtatgggctt tagttggatg tgtttggata tagtagatat cgtcgacgtt tactttatag
    30601 actgttttct gcgtctgaat aatcatatgt ttcattggat tctcctccta agaaaagaat
    30661 aacagaaaag gtctagccca agcccaccca atcctaaaca gtctttgaaa gctcctaaaa
    30721 ggattatttt tctacaacat catgatgagc ttacaactat tttatcataa aattcactca
    30781 gcgcaattca agacatttca atgacaatta aagatttgaa taaaaaaaaa gaattaaaag
    30841 tgataaacta acagtatcaa aacacagttg ccagaagtaa gactggcacc cagattaaag
    30901 gaggcattcc catgacagat acagacccca tcaaaagagc tcatactttg attactgact
    30961 taaacaaagc ctaccaagca tgcaaacagg caagcgctga cgacgtccgc tttcaggagc
    31021 aattaaactc tattcttggt tttctagcca agactgaaac agtggataat cgattcttga
    31081 ttgaactaga aaaattttac cagacttcca gtcttctcat gggactcagc gctcttgatc
    31141 cagatgctcc aactcgcgcc gcttggcggg cctatgaccg cttccacttt gaccaagtca
    31201 agaccaagtt aatactcaat gagaatcaaa gagcaaacta ggaagctagc cgcaagctgt
    31261 acttgagtac ggtaaggcga cgctgacgtg gtttgaagag attttcgaag agtataagtc
    31321 tctacggacc aaccattatc ctgtagtaac aaaaaagaag ctgagacaaa ctgaactcaa
    31381 cttctttttt agtgtcgtat cagcaatgtt agtcctgcat ctgacgtttt acctgataag
    31441 gcaaatacaa gactagtaaa accaaaccag ctcctagtaa ggctagaagg gctagttttt
    31501 cttggaaggt aatcaaccca acaactaatt ccacaagtaa aacaaaactg gtcaatcctc
    31561 gaactacctc ctgtaagcct ttttcctttt gccccttgtc cagcggaaag agttgggtca
    31621 aatactggta gtcaaaggca tgatagaggg ccagcaactg gaagagcaag aggtagttaa
    31681 agagaactac cactgctgtc gcaatccaag cttgctcgat aaaaacctgc gccagtacgg
    31741 aaagtaagag aagacgaaga ctgagagcaa agaggtcgcc atttcgcaga taagaacgca
    31801 gatagagatt ttgccaaatc ttcccaggca ccttctgaac agcctttaag ataaagtcca
    31861 gataggcacg acgcttgaca ctgtttgaaa ttcccttgac ctgcgtaaag agggcaaaga
    31921 aacgaagcaa gacttgctta cgcttgcttt cttgagaaat aagatagtcc cagtccagtc
    31981 cagtttcagt gaaaaatttg ctggcctttt gacgaaagtg gaaatatttt cctaccccca
    32041 ataaaagcac atagagcaga aaaactggca agccataacc cattgctaaa aataaaggcg
    32101 caaataacag caagaaaagg gtctgtacaa agagccaaaa gactagggaa atgccagttt
    32161 gacgcttgag atggagcttg atttcctctt ctccaactaa gagaaagagc ttgtctggag
    32221 cctccatata ggtggcaatt cctccccaaa gtaagagtaa aacagacgta attcctacaa
    32281 acaaaaggat aggccaatga ttttcaggaa aatgttgtaa gagttgactg tactggtagg
    32341 ctagaaagcc caacaggaca agcaggaaca agacaaagtg gtcattgagc acatagcgca
    32401 gataaccaag acactcctta cgaaaggcct gctttctctt taaaaacaag tctttcatag
    32461 atcctcctct ttggtcagag ccaagtaaat atcattcaaa ctagcctcag gcatatcaaa
    32521 ggcttcacgt agttgcagga gattgccttt ggcacgcacc tctcccttgt gaagaatgac
    32581 aaaggcatca cacatcttct ccgccgaatc cagcacgtgg gtactcatga gaatagactt
    32641 gcccttttgc ttctccactt ccaaaagctg aatcaaatca gaaatagcca gcggatcaag
    32701 accaaggaaa ggctcatcca cgatgaaaag acttggatcc accacaaaag cacagataat
    32761 catgaccttc tgcttcatcc cttttgaaaa atgaacaggg aaccagtcta atttctggtc
    32821 cagacggaac atctttaaca agggctctac tcgttcgaaa gccacttttt gctcaatacc
    32881 gtaagccata gcaaccgttt cgatatgctc tctgagggtc aattcctcat acagactagg
    32941 cgtctcagga atgtagccaa tctgcttgcg gtagctagtc gcatctcctt gcagagtcag
    33001 gccattgata ttgatggagc cactataagg tgccaacaga ccgataatct cattgatcgt
    33061 cgttgatttc ccagcaccat tgagaccaat caaaccgacc aactgcccac tttcaacagt
    33121 aaaggacaca tctttcaaaa caggaacatg aacatagcca cctgtcaggt ttttaatttc
    33181 taacatattt tctccaaatc tggtataatg tagctatatt atatcaaaat tcagtacagt
    33241 agaggtagat tttatgtcag attgcatttt ttgtaaaatc atcgcagggg aaattcctgc
    33301 ttcaaaagta tatgaagatg agcaggtcct tgcctttctt gatatctctc aagtaacact
    33361 aggacacacc ttggtcgtgc caaaagaaca ctatcgcaat cttttggaga tggatgctac
    33421 gagcgccagc caactctttg cccaagtacc aaaagtagct caaaaagtca tgaaagtcac
    33481 taaggctgct ggtatgaata tcatttccaa ctgtgaagaa gtcgctggtc aaacagtttt
    33541 tcatactcac gttcaccttg tgcctcgcta cagtgctgac gatgacctca agattgattt
    33601 tatcgcccac gaaccagact ttgacaaact tgctcaagtc gctgaaacca tcaaaaacgc
    33661 ttaaggagtt gctatgaaat tatccaacct actgctattt gcaggagctg cagccggaag
    33721 ttatctggtt acaaaaaatc gccaaaccat cacagatgaa gtcttgaata ccactgaccg
    33781 cgttcaagct atcaaggacg atgtggatat tatccaaaac agcctgcaaa tcattaacca
    33841 gcaaaaagaa cttatcaagg aataccaaga agacttgact tacaagttta aggtcttgga
    33901 aaaggatatc cagactagac tagctgtgat aaaagaaatg cagggaactg aagataagta
    33961 aaaagagccc cccggctctt ttttaaaacg taaacaagtt atagtgaatt gaatttagaa
    34021 tagcacatca tagtttctaa agcattgcta gagattactt taaaatcctc ttatcaattt
    34081 gttcatattc tatttcaatc tactatatat atcccatcaa ctatgcatca taatttaggt
    34141 aactcatact caataaaaat caaaaagcaa actagaaagc taggcacaga ctgctcaaaa
    34201 caccgtttta aggttgtgga tagaactgac gaagtcagct caaaacactg ttttgaggtt
    34261 gtagatacga ctgacgaagt cagctcaaaa cactgttttg aggttgtgga tagaactgac
    34321 gaagtcagta accataccca tgacaagccg acgctgacgt ggtttgaaga aatttttgaa
    34381 gagtatcatt caccatttca caactaaatc gaagactttc tgccgtaatg aaaacacctg
    34441 aaacagcttg gtttcagctg tccggaaact ttaagactta ggttcaaagt ttaggtatgg
    34501 aacttcgaag aaggtcgcta ccgtccgtca ttacttagga aagtcttaaa aaatctataa
    34561 agtaaaaaga gcccgacagc tctttttgtt tatactcaat gaaaatcaaa aagcaaacta
    34621 ggaaactagc cacgggctgc tcaaaacact gttttgaggt tgtagatacg actcacatat
    34681 atacggcaag gcaacgctga cgtggtttga agagattttc gaagagtatt attctccatc
    34741 aaaggcatct ttaatatggt caaagaagcc ttttttcttt ggatttactt tcaagccacc
    34801 agcagccgcg aattctttca aggctacttt ttgccggtcg ttcaagcctg tcggtgttac
    34861 gacattaaca gtaacgtatt ggtcaccaac tgcaccgcca cgaaggctcg gtgccccctt
    34921 actacgtagg cggaatttct taccagtctg agttccctct ggaataacca attcaacatc
    34981 accgtgaaca gttggaatat ctactgtatc accaagagcc gcttggacaa agttgaggtt
    35041 gagattgtag aagatagtcg ttccttcacg ttcaaacttg tcgctagctt ccacagaaac
    35101 tactacatac aagtcaccat aaggtccacc gttaaagcct gcttcacctt gaccagcgag
    35161 gcgaatttgt tgacctgttt ccacaccagc agggattttc acatgtacgc tatgagcttg
    35221 tttctcatga cctgttccat gacaggttgt acatggatat ttgatttctt ttcctcgacc
    35281 gtgacagaca tcacaggtta cttggcgacg catcatacca agaggagtct gcgtatcgac
    35341 gttaatgaca ccagcgccat gacagcgtcc acaagtgact ggacttgtcc ctggcttagc
    35401 accagagcca ttacatgtac gacagccagc ttcacgatga tacttaactt ccttctcagt
    35461 tccgaagata gcttcttcaa aggtcaaatt gacacgatac tggagatcat ctccttggcg
    35521 aggagcgttt ggattgcgcg aagaaccgcc tccgccgaag aaacttgaga aaatatcctc
    35581 aaaaccaccg aaaccacctg ccccattgaa accgccgaaa ccaccagctc caccaaaacc
    35641 accattggcg cctgcagcac catactggtc ataggcagca cgtttttggt cgtcactcaa
    35701 agtctcatag gcttcttgaa cttccttgta cttgtcctca gcaccaggct ccttgttgat
    35761 atctgggtga tattttttgg aaagcttacg ataagccttt ttgatttcgt ctgccgaagc
    35821 gtttttggat acccccagac gatcataaaa ttcagtattg ttcataattc aagatacaaa
    35881 gggcgtcaaa cggacacagc catctaggag ttttgacgac ggacgcttac gtcctagaaa
    35941 aaactatctt ttgggcacag tccgtagccc gtgttcagtt acgaacaccc ttattccttt
    36001 ctattgatgt tctgaatcga accaccattt aggtcgggtt caattccttt cttttatatt
    36061 tagtaagaaa ttctgaaacc cgtgttcagt tacgaacact ctttgttccc ttctattgat
    36121 gagacaaaac ccaaacaaat gagattccgt ccctttttat cgaaaaacag aggctgggtt
    36181 gcaacctctg caaataagta aattaacttt attttgattt taaatatcct ataagtacag
    36241 aaatatttat atatttttgt ctcttcttag tatttgccta tataattcca attgatcata
    36301 agaaatacaa ctactgtcca aatcatacca attatgaacg gtattacaaa tttatatgtt
    36361 tgtatttcta atgatatcat agctgatacc agcgctgata caaatgcaga caacaatact
    36421 gaggtaacaa aattccttac cgcttcatca tttttgatac aactatcatg ttcagctaat
    36481 ataatttctc tatatctagc taaacattct attggaatat tatcaataaa atcttttgat
    36541 gttctatagt tatcagcttg attacaaaaa tcattataaa cttttcgtgt attttttaga
    36601 tactcttcag ccaatacact catcttactt ttccgtaaac tctccgtcta cgacgtcatt
    36661 gcctgcgttt cctgttgctt gtgcgccttc tgctccttct tgagcttgtt gcgctgctgc
    36721 ggcttgttcg tagagtttaa cagcaagtcc ttgagctttt tcgttcaatg cttcaagttt
    36781 tgttttcatg tcgtccaagt tgttgtcttc ttgagctttc ttaaggtcat caagggcagc
    36841 ttgggcagcg tcacgttctg cgtcgaagcc tttaccttca gtttccttga ttgtcttttc
    36901 agtcgcaaag attgcttggt ctacttcatt acgaaggtct acttcttctt tacgtttctt
    36961 atcggcttca gcgtttgctt ctgcatcttt catcatgcgg tcgatttctt cgtcagtcaa
    37021 acctgagttc gattggatga caatagtttg ttctttttga gttccaaggt ctttggcctt
    37081 aacagacacg ataccgttct tgtcgatgtc aaatgttact tcgatttgag gaattccacg
    37141 aggtgcagct gggatatcag tcaattggaa gcgtccaaga gtcttgttat ctgctgccat
    37201 tgggcgttca ccttgaagaa cgtggatatc aacggctggt tggttgtctg ctgctgttga
    37261 gaagacttgt gatttagatg ttgggattgt agtgttgcga tcgataagtt ttgtaaatac
    37321 tccacccatt gtttcgatac caagtgacaa tggcgttaca tcaagaagga caacgtcctt
    37381 gacatcacca gtaatcacac caccttggat agccgcaccc atagcaacta cttcatcagg
    37441 gtttactgat ttgtttggtt ctttaccagt ttcagcttta acagcttcaa caacggcagg
    37501 gatacgagtt gaaccaccaa caaggataac ttcgtcgatt tctgacaagc tcaaacctgc
    37561 atctgaaagg gcttgacgaa ctggaacttt tgtacgttca acaaggtcac gagtcaaatc
    37621 gtcaaatttc gcacgagtca aagtcatttc caagtgaaga ggtccagcct cacctgcagt
    37681 gataaatggc aagctgattt gtgttgaagt tacaccagaa aggtctttct tcgctttttc
    37741 agccgcatct ttcaaacgtt gcattgccat cttgtcagta gacaagtcga taccgttttc
    37801 tttcttgaat tctgctacca agtggtcaat gattttttgg tcaaagtcgt caccaccaag
    37861 tttgttgtcc cctgcagttg acaatacgtc gaagacaccg tcacccaatt caaggataga
    37921 gacgtcgaat gtaccaccac caaggtcaaa taccaagatt ttttcttctt tgtcagtctt
    37981 gtccaaacca taagcaagag ctgctgcagt tggttcgtta acaatacgtt ctacttcaag
    38041 accagcaatt ttaccagcgt cttttgttgc ttgacgttga gcgtcgttga agtaagccgg
    38101 aactgtgata acagctttgg ttactttctc accaaggtag tcttcagcgt agcctttcaa
    38161 gtattgaagg atcatagctg agatttcttg tggagtgtat tcttttccat ttgcagaaac
    38221 tttttcagaa gttcccatct tagatttgat agagataact gtatctgggt ttgtaactgc
    38281 ttgacgtttt gcagcatcac caacgatgat ttctccgttt ttgaatgaga ctacagatgg
    38341 agttgtgcgg tttccttctg ggtttgcgat gattttgctt tcagttcctt caagaactgc
    38401 aactgctgag tttgttgtac ctaagtcaat accgataatt ttagacatgt gtttttctcc
    38461 ttgttagtta attttctatt tttctttttg atactcttct taagtggcga cgccgtcaga
    38521 gcttgacttc gtcaatctct ttgactaaac tttgagccta aggtctcaaa atttgcgcaa
    38581 atagcgccac ggcgaagagt atcgtgtttg gttcgcttcg ctcactatta caaagccaaa
    38641 catattttat ctttcttcat agtttattgt cgtttcggac aagttttcta ttatgtaaat
    38701 tgcgacacga ggagtcgaaa tcgattttat ttcgacgacg agttagtaag gaagctaggc
    38761 aaacgccata gcgattgccg ttttctgacg agttgcttta gctaccgtca gaattgccga
    38821 atcgaacacg ccctaagctc tgagtaaaaa agatagattt tcttgtgttc atcgaacact
    38881 tcgtcaatct cctattttta ctgcgagctt tttacgggct ttatatctta gttatacacc
    38941 actaccattg ctgggcgtag gatgcggtca tggagtttgt agcctttttg aaagacttga
    39001 gcgatggtat ctactgggtg ttcatcgtct gctgggagag tttggatggc catatggtag
    39061 ttatggtcaa attcgccatc tgctgcgatt tcttcaattc cttcttcttt caaagcgtga
    39121 atcaagcttt cttgcaccat ccccaagccc ttcttcacat catctgtcaa accttcaact
    39181 gcaagtgcac gctcaaggtt gtcaagagat ggtaagattg cttttgccaa gtcctggcta
    39241 cgataacgtt gcaagttttg acgttcttca ttggcacggc gttggatatt ttgcatttct
    39301 gcatgagcgc gaagatattt gttttcgaac tcatctgcac gttcatttgc caagtccaac
    39361 tcagactttt caggagttgt ttcttcagct gtttccacaa cttcctcttc ttgaacttct
    39421 tctacttctt cattttttat atcttgggcc atgttcgcct cctttaatga tttcaatctt
    39481 aatgtacttc gtaatgatta ctgctgaggt agcggtaaaa atctgtcaac ttcatggtca
    39541 aaacacggtt gaccacattg atttgattga ttagctgttg gtaatccaga ttaactggac
    39601 cgataatggc tagaattcca actccccgat aaggaatgag gaacttacta ctaatcaccg
    39661 ctaggtcagc taaacaggac tcttgaccgt ctgcaacacg aacattttgc atctgatcct
    39721 cacgcaaccc ctcacgaatc tccaaggcca ccttttgcgg ttggtcaaag aactgatagg
    39781 ctgctagatt ggcaaaattc aagagattga ccttgcccgc catcacaatg ttttcgttga
    39841 acatttcctt aaagatgtgt tcaaagagat cgatgacatt atccgttgtt gtaaagtaac
    39901 gctggataat ctgcggaatc tccgtccgaa tcttgtagtg aatatctaaa acggtgtgac
    39961 cgaggaaacg ttcctgaatg atgctcttca gtttcagcaa atcctcctgc aagaagttcc
    40021 ttggaatcag aaactgacta gtaaccgttc gcgactcgtc tagggtaaat accgccaagg
    40081 ctgtatgttg ccccaaaaca acgatatcaa aggctgtcaa acgttgcctg ctcggctcaa
    40141 catccagtgc cactaccgta cagccactca ggtctgttag caagttagca gcctcttgca
    40201 gaatatcctc caatttgaag aattcctgat caaaggcttt gacaatctca tatacctcat
    40261 tttcagccag tcggtcaaaa tccagtgagt gtttcacata gtactgaaaa ccagcaacac
    40321 ttggcatccg accgcttgaa gtatgagcct tctcaagcaa cccttgtttt tctagttccg
    40381 ccatgtcatt acgaatggtt gcactgctag agttaataga ctcttgcaag gcttttgatc
    40441 cgacaggttc gtgcgttttg gtaaagatgt caataatcag atttaaaata tcctgctgac
    40501 gctctgtaac catctcatca ctcctctctg tctgatcaat tagcactcaa tgcatccaag
    40561 tgctaactca tgattctatt atacaccctt agaagagaat gtcaagacaa aaactcaaaa
    40621 aattagcact cttttatcaa gagtgctaaa aatcaatctg aagacctaga accttgctat
    40681 tcatctactc ggtatttcct ttttagtctg aaataaccat gaattagata agaaatcaga
    40741 aaagcatata aaacaaaaat aagaaagaaa gacatagaaa gttcctctct aaacaaactc
    40801 atacaaacaa caagaccacc taagaaagta gctgtacagg aacgaagtct agatcgcata
    40861 acttcccatt tgagcccctt actcatatag acttgatcct ctggaagtaa atcagaagac
    40921 gatttacgaa gaatcgaaca agaacctgct cctatcaatt cccaacctct atctctaaat
    40981 tcttgcagtt catgcttata ttttttaaga aatctagaat catagatacg gtagatgaca
    41041 tcgtctggtt gacattggtc aaaatagaac aaaccaaaac gactcgttct atacctccaa
    41101 cctttcaaat gcatctcatg taaatattct tcttccttgt ccaaatcaag aatggtgaaa
    41161 atccgaaatt ctactctgct attcattgtc ttaccccaaa attagaaaac atgcctggcg
    41221 ttatttatta gataattctt tccacttttg actcaatctc caaaaaatat aagaaatctg
    41281 aatcgcaaaa actatcaata aaacccaatc tattatgaaa gtcaaaaaca cttcccaact
    41341 gaaagaacta cctccagtga caaactttga gaaaaacggt agtagagcta aaaagagaag
    41401 caaaatagga agcatccgca ttgttaaaat ccttttggca taaaaaaatc tttatttaaa
    41461 cgaaaatatt atggcaaaat ttacgccagt ttttgaacgg ctgatgtaga tattttatac
    41521 tttcaaaatg tttaaatgtg attatttatt tttgaaaaat agctcaccag cccgactgaa
    41581 agtgcttata aatgataata agtcgcctgc cgaaaacagc gaaaaatagc ggtgttatgc
    41641 ggagataatc tgacgcgatg cgaaagtata ttgcatactt attttcaaca atttagcaga
    41701 gtatttttat aagtgtgata taatagaagt ataatttgtt ctgatagttt attttatgga
    41761 gaagtagatt tttagaatgc ggagggttca atatggttga gtttataaag tctaagaaag
    41821 aaatgagtga ggaggatatt aaagcaaatt tcatcactcc tgctattgta tccaaaggat
    41881 ggaaaaatgg tgagcatatc gcttacgaag aatacttcac tgatggtcga attgaggtta
    41941 gaggagataa ggctcgtcgt aaagaaggaa aaaaatcaga ctattcactg tattaccaat
    42001 ttggaactcg aattgcaatt gttgaggcaa aggataataa acacagcgtt cgagcaggat
    42061 tacaacaagc tattgaatat ggagagattt tagatgttcc atttgtttat tcttcgaatg
    42121 gtgatggctt tattgaacac gaccgtatca cgagagaaga acgtgagctg gagttagacg
    42181 aattccctac tcgtgaagaa ttattttctc gtatgacgaa ggaaaaagga ttgacgtacg
    42241 aaattacaga agctatctca actccatact atacagacgc cttctcaatg aaaacgccac
    42301 gctattatca gcaaatagct atcaaccgta ctattgaaac agttgccaga ggacaaaaac
    42361 gagtaatgtt tgtgatggca acaggaacgg ggaaaacgtt catggctttt caaattattc
    42421 atcgccttcg aaaagctggt ttggctaaac gagttttatt cttagcggat agaaacatct
    42481 tagtagacca aacgatggct gaagacttta ggccattcga aaaggtaatg acgaaaatta
    42541 caccaaaact tttgactgct cctgaaaaat taaattcttt tgaaatttat ctagggcttt
    42601 atcagcaact aactggtgaa gatggaactg aaacacatta tcaaaaattt gacaaagact
    42661 tctttgattt aatcgtaatt gatgaagcgc accgtggttc agctaaggaa aacagtaact
    42721 ggcgtaagat aattgattat ttcagttctg cgacacagat tgggatgacc gctactccta
    42781 aagaaaccaa gaatgcttcc aatacggaat actttggtga gccaatctat acttatagtt
    42841 taaaacaggg aatcgaggat ggttttttgg ctccatatcg tgttatgaga gttaatttag
    42901 atgtagatgt ggatggttat cgtccagaaa ctggaaaagt tgatgctaac ggacaattaa
    42961 tagaagatag gtactacggc aggaaagatt ttgataaaac cattgtcatt gatgatagaa
    43021 cgcaaagagt tgccaagttt gtttctgatt atatgaagca aaacaatgca cgatttgata
    43081 aaacaattgt tttttgtgtt gatattgacc atgccgagcg aatgcgtgct gcacttgtaa
    43141 aagagaatct agacttagtc caagaagact atcgttatgt catgcaagta actggtgaca
    43201 acgctgaagg aaaagctcaa ctggataact ttatggatgt caattctaat tttcccgcta
    43261 ttgtaacaac gtctaaatta ttaacgacag gagttaatgc taaaacatgt cgtttgattg
    43321 ttttagactc taatatccaa tccatgactg aatttaaaca aattattggt cgtggcacac
    43381 gtctttatcc tcaaaagggg aaagaatttt ttacgattat tgattttcga aatgttacca
    43441 atttgtttgc tgaccctgat tttgatggtg atccagtgaa ggtgctggaa acaggtgcga
    43501 aaacagtcag tggttctacg cccggtttcg taagtgagga aggtgaccca gtagaaaaat
    43561 atatcgttac agacaagcag gttaccattc ttaattctac tgttcaagta ttggatgaaa
    43621 acgggaaact gattaccgaa agcctgaccg actacactcg gaagaatatc ttaggtagct
    43681 acgccacttt gaacgatttt atcacagttt ggcatacggc ggataaaaag aagcttatct
    43741 tagacgaact ttataaaaaa ggagtttatc tagatgctat tcgagagtcg gagggaatat
    43801 cagaacaaga aatcgatgat tttgatttac tcctaaaact tgcctatggt caaaaagaat
    43861 taaccaaaac ggaacgtatc aataagctca aacaaagcgg atatttatat aaatatagtg
    43921 aggaagcgcg tgctgttttg gaaattttac tgaacaaata catggataaa ggtattggag
    43981 aactcgaaag cattgaaaca ttaaaacttc cagaatttca gatatatggt ggaaccttca
    44041 aaatcatcaa tacttatttt ggagataaaa aacgatattt acaagcaatt aaagaattgg
    44101 agcaagagct atttacagta gcttaatgaa aggaaagtat gtcaattaca tcatttgtaa
    44161 aaagaattca agatatcact cgaaacgatg ctggtgttaa tggtgatgct caacgtattg
    44221 agcaaatgtc ttggttatta ttcttaaaaa tttatgatag ccgtgaaatg gtttgggaat
    44281 tagaagaaga cgagtatgag tcaattatcc cagaggaatt aaaatggcga aattgggctc
    44341 atgctcaaaa tggggaacgg gtattgacag gcgatgaatt acttgatttt gtcaataaca
    44401 agttattcaa agagttgaaa gagcttgaaa taacttcaaa tatgcctatt cgaaaaacga
    44461 ttgttaaatc agcttttgaa gatgcgaaca actatatgaa aaatggcgtc ttgttacgcc
    44521 aagtcatcaa tgttattgat gaagttgatt tcaatagccc tgaagatcgt cattcgttta
    44581 atgatattta cgaaaaaatt cttaaagata ttcaaaatgc tgggaactca ggagaatttt
    44641 atacgccacg tgcagcgact gattttattg ccgaagttct tgacccaaaa cttggagaat
    44701 caatggcaga ccttgcttgc ggaacaggag gcttcttgac ttcgactctg aaccgtttaa
    44761 gtagtcaacg taaaactagt gaagatacca aaaaatataa tacagctgtt tttggtattg
    44821 aaaagaaagc atttcctcat cttttagcag ttacaaatct gtttcttcac gaaattgatg
    44881 accctaaaat tgttcatgga aatactttgg agaaaaatgt tcgtgaatat acggatgatg
    44941 aaaaatttga cattattatg atgaatccac cttttggagg gtcagaatta gaaacaataa
    45001 aaaataactt tccagcagaa ttacggagtt ctgaaacagc tgatttattt atggctgtca
    45061 ttatgtatcg tttgaaagaa aatggtcgtg ttggagttat tttacctgat ggttttctat
    45121 ttggtgaagg tgtaaaaact cgcttgaaac aaaaactggt agatgagttc aacttgcata
    45181 cgattattag gttgcctcat agtgtctttg caccgtatac aggaatccat acgaacattc
    45241 ttttctttga taaaacaaag aaaacagaag aaacttggtt ttatcgttta gatatgccag
    45301 atggttataa aaatttctcg aaaactaagc cgatgaagtc agaacacttc aatcctgttc
    45361 gtgactggtg ggaaaatcgt gaagagattc tggaaggtaa gttctacaaa tctaaatcat
    45421 ttacacctag tgaattggct gagttgaatt ataatttaga ccagtgtggt tttccaaaag
    45481 aggaagagga aatcttaaat ccctttgagt tgattcagaa ttatcaagcg gaaagagcaa
    45541 ctttaaatca taagattgat aatgtattag ctgatatttt gcagttgttg gaggacaaat
    45601 aatgacacca gaacaactta aggcaagtat tctccaaaga gcgatggaag ggaaattagt
    45661 gccgcaaaat cccaatgacg aacctgcaag tgaattatta aagagaatta aagctgaaaa
    45721 agaaaaactt atcagtgaag gaaaaatcaa acgagataaa aaggaaactg agatatttcg
    45781 tggtgatgat g
//
LOCUS       DAVEHY010000017        39857 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVEHY010000017 DAVEHY010000000
VERSION     DAVEHY010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.017"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(131..1618)
                     /locus_tag="VUZ44_001120"
     CDS             complement(131..1618)
                     /locus_tag="VUZ44_001120"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU0320040.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(1767..2507)
                     /locus_tag="VUZ44_001121"
     CDS             complement(1767..2507)
                     /locus_tag="VUZ44_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU0320041.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(2507..4672)
                     /locus_tag="VUZ44_001122"
     CDS             complement(2507..4672)
                     /locus_tag="VUZ44_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU0320042.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            4845..5798
                     /locus_tag="VUZ44_001123"
     CDS             4845..5798
                     /locus_tag="VUZ44_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0320043.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSSLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLVLFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            5875..7863
                     /gene="uvrB"
                     /locus_tag="VUZ44_001124"
     CDS             5875..7863
                     /gene="uvrB"
                     /locus_tag="VUZ44_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU0320044.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            7873..8436
                     /locus_tag="VUZ44_001125"
     CDS             7873..8436
                     /locus_tag="VUZ44_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320045.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            8402..8922
                     /locus_tag="VUZ44_001126"
                     /pseudo
     CDS             8402..8922
                     /locus_tag="VUZ44_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8975..9442
                     /locus_tag="VUZ44_001127"
     CDS             8975..9442
                     /locus_tag="VUZ44_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU0320046.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPDTNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLRS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYRHRTEDDWEKKIF"
     gene            complement(9439..9954)
                     /locus_tag="VUZ44_001128"
     CDS             complement(9439..9954)
                     /locus_tag="VUZ44_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU0320047.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALEQLGYLVKD"
     gene            complement(9966..10493)
                     /locus_tag="VUZ44_001129"
     CDS             complement(9966..10493)
                     /locus_tag="VUZ44_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU0320048.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(10775..11338)
                     /locus_tag="VUZ44_001130"
     CDS             complement(10775..11338)
                     /locus_tag="VUZ44_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU0320049.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(11322..11873)
                     /gene="coaC"
                     /locus_tag="VUZ44_001131"
     CDS             complement(11322..11873)
                     /gene="coaC"
                     /locus_tag="VUZ44_001131"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU0320050.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(11885..12574)
                     /gene="coaB"
                     /locus_tag="VUZ44_001132"
     CDS             complement(11885..12574)
                     /gene="coaB"
                     /locus_tag="VUZ44_001132"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU0320051.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQTKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            12804..14474
                     /locus_tag="VUZ44_001133"
     CDS             12804..14474
                     /locus_tag="VUZ44_001133"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU0320052.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            14802..15977
                     /gene="mutY"
                     /locus_tag="VUZ44_001134"
     CDS             14802..15977
                     /gene="mutY"
                     /locus_tag="VUZ44_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU0320053.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            16032..16736
                     /locus_tag="VUZ44_001135"
     CDS             16032..16736
                     /locus_tag="VUZ44_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320054.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            16729..18078
                     /gene="vicK"
                     /locus_tag="VUZ44_001136"
     CDS             16729..18078
                     /gene="vicK"
                     /locus_tag="VUZ44_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU0320055.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            18080..18889
                     /locus_tag="VUZ44_001137"
     CDS             18080..18889
                     /locus_tag="VUZ44_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU0320056.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            18980..19222
                     /locus_tag="VUZ44_001138"
     CDS             18980..19222
                     /locus_tag="VUZ44_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU0320057.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            19224..19478
                     /locus_tag="VUZ44_001139"
     CDS             19224..19478
                     /locus_tag="VUZ44_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU0320058.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            19525..20298
                     /locus_tag="VUZ44_001140"
     CDS             19525..20298
                     /locus_tag="VUZ44_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU0320059.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(20558..21544)
                     /locus_tag="VUZ44_001141"
     CDS             complement(20558..21544)
                     /locus_tag="VUZ44_001141"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU0320060.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            21738..24206
                     /gene="gyrA"
                     /locus_tag="VUZ44_001142"
     CDS             21738..24206
                     /gene="gyrA"
                     /locus_tag="VUZ44_001142"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU0320061.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            24206..24949
                     /gene="srtA"
                     /locus_tag="VUZ44_001143"
     CDS             24206..24949
                     /gene="srtA"
                     /locus_tag="VUZ44_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU0320062.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            25193..25990
                     /locus_tag="VUZ44_001144"
     CDS             25193..25990
                     /locus_tag="VUZ44_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU0320063.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            26138..27397
                     /locus_tag="VUZ44_001145"
                     /pseudo
     CDS             26138..27397
                     /locus_tag="VUZ44_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            27493..28767
                     /locus_tag="VUZ44_001146"
     CDS             27493..28767
                     /locus_tag="VUZ44_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU0320064.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            28777..29655
                     /gene="truB"
                     /locus_tag="VUZ44_001147"
     CDS             28777..29655
                     /gene="truB"
                     /locus_tag="VUZ44_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU0320065.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEDATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            29897..30199
                     /locus_tag="VUZ44_001148"
     CDS             29897..30199
                     /locus_tag="VUZ44_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU0320066.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFSLWIAKAPSQERGRLAFLQMLAQILQGFR"
     gene            30307..30945
                     /gene="udk"
                     /locus_tag="VUZ44_001149"
     CDS             30307..30945
                     /gene="udk"
                     /locus_tag="VUZ44_001149"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU0320067.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            31073..32413
                     /locus_tag="VUZ44_001150"
     CDS             31073..32413
                     /locus_tag="VUZ44_001150"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU0320068.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            32391..32603
                     /locus_tag="VUZ44_001151"
     CDS             32391..32603
                     /locus_tag="VUZ44_001151"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU0320069.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            32600..33475
                     /locus_tag="VUZ44_001152"
     CDS             32600..33475
                     /locus_tag="VUZ44_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU0320070.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            33468..34283
                     /locus_tag="VUZ44_001153"
     CDS             33468..34283
                     /locus_tag="VUZ44_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU0320071.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            34276..34707
                     /locus_tag="VUZ44_001154"
     CDS             34276..34707
                     /locus_tag="VUZ44_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU0320072.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            34714..36381
                     /gene="recN"
                     /locus_tag="VUZ44_001155"
     CDS             34714..36381
                     /gene="recN"
                     /locus_tag="VUZ44_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU0320073.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            36383..37111
                     /locus_tag="VUZ44_001156"
     CDS             36383..37111
                     /locus_tag="VUZ44_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU0320074.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            37190..39013
                     /gene="lepA"
                     /locus_tag="VUZ44_001157"
     CDS             37190..39013
                     /gene="lepA"
                     /locus_tag="VUZ44_001157"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU0320075.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            39427..>39857
                     /locus_tag="VUZ44_001158"
     CDS             39427..>39857
                     /locus_tag="VUZ44_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU0320076.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKIS"
BASE COUNT        11976 a         7137 c         8994 g        11750 t
ORIGIN      
        1 cttttcatta tagatcttat gggacttttt ttctacaata aaataggctc cataatatct
       61 atagtggatt tacccactac aaatattata gaaccaaatc ctgcaaggca taaacttgca
      121 ggaaattttt ttattcgaaa cgaccatctt gacgataggc gatatctggt tgccaagtcc
      181 atttggcacc gaatttttca agtaggtcaa agctggcttg aggtcccatg cttccagctt
      241 tatagtcatg aagtggggca ccattttcag cccagagctc ttcaatacgg tcaatcaact
      301 tccatgacgc accaacctca tcccagtggc taaagttagt tgagttgtta tttaggacat
      361 cataaatcaa tttttcgtat ggttctggag aagcaccagt tgcagtcgca tctgtacggt
      421 aatcaagtga gttaggagcc aagttaaatt cttctcctac ttgcttccca tttaggctaa
      481 gagagaagcc ttctgttggt tgaatataga tggtcaaaat atttggagca agtggttctc
      541 caaagataga atccatttgt ttaaagacga tgttgacatg agttcctttt tcagtcagtc
      601 gtttacctgt acggaaaaag aaaggaacac tacggaatcg atcgctgtct acaaagaagg
      661 caccagatgt aaaggtttca gttgttgatt ctggattcac atttggctcg ctacgataag
      721 agatgtattt catgccatca atcttaccag agcggtattg cccacggata aagtgttctt
      781 tgagttcttc atcagttgga tgatagaggt ttttaaagac cttaatcttt tcagcacgaa
      841 tctcgtcttt tgtgaagctt gctggtttgt ccatggcgag gagcgaaaga agttgtagag
      901 tgtggttttg gaccatgtca cggagggcac cggattggtc atagtagcca ccacgttctt
      961 ctacacccaa gcgctccgca aaggtaattt gaacattgtc gataaaatcc ttgttccaaa
     1021 cgttttcaaa aatcaagttt gcaaagcgaa ctgcaaagat gctttggatc atttccttac
     1081 caagataatg gtcgatacgg aaaatttgtt cttcgtcaaa tgttgctagg agttcgtcat
     1141 tcaacttgct tgcagttgcg taatctgtac caaatggttt ttcaacgatc aagcgctcaa
     1201 aacctttgcc atcgacaatg ttttcagatt tgaggtgttt ggcaatggtt ccaaagaact
     1261 gaggtgccat agacaagaag aagagcttat tgtgttcagc ttggtatttt tcattaagct
     1321 cagcttgtaa ttgacgcaaa gcaatataat gttccgaatc attgacatca tggctttgat
     1381 agtagaagtg gctagcaaat tcttgggctt gctcggtact atctgccaaa tcaaggatgg
     1441 actcgacaac tacagattca aaatattcct tactccaagg tctacgggca gttccaataa
     1501 cggcaaagtg cttggaaaga ttgccggatt gatatagtct aaaaagggaa gggtagagct
     1561 tgcgtttagc caggtctcca ctcgcaccga aaattgtaac aataacctta gatgacatct
     1621 agctacctaa tttctatttt tattcctagt cttgctaggt atgaggaaac ctcatttcat
     1681 aaacttaatt ctaacataat tttccgaaaa atcaaaaatt ccaatacgag gtagaaaaac
     1741 tgcaaggaaa tccttacagt ttgagtttag acgtttaaga ccttatctaa gaactctttc
     1801 agacgagggt gttgtgggtt atcaaagatt tggtcaggtg ttccgtcttc aaggaactcg
     1861 ccatctgcag taaagataac gcggttggca acctgacgag caaatcccat ctcatgggtt
     1921 acgataatca tggtcatgcc ttgctcagcc aattccttca taacgttaag tacgtctcca
     1981 accatctcag ggtcaagggc agaagttggt tcatcgaaga gcatgatgtc tggattcatt
     2041 gctaggccac gagcgatggc cacacgttgt ttttgaccac ctgataggct atctggattg
     2101 gcattagctt tatctgctag tccaaccttt tcaagcaact ccattcccaa ttcctcagct
     2161 tcttccttag tcatcaactt gtgctcaata ggagcaaagg tgatgttgtc caatacagac
     2221 atatgaggga agaggttgaa gtgttggaat accatgccga tattttcacg gacgtggtca
     2281 acattggttg ttttttcagt taaatcatag ccgttcacag tgatgtgacc gctagtgact
     2341 tcttctaaaa gattgaggct acggaggaaa gttgacttac cagaacctga aggaccgatg
     2401 atacaaacaa catctccttc atagaactta gtcgtaattc cttttaggac ttcatttttt
     2461 ccatagtact tgtgtaaatc atttacatca atttttaatt ttgccattaa cgaatcctct
     2521 tttctaagcg tttcgctagt ctagtcaaaa gtgtgataat tacaagatag aagatagcaa
     2581 ggattgcata catcttgaaa ctttggtagt tacgagcaat gataatctta ccagtttgga
     2641 agagttcaac taaaccgata gcagatacga tagttgtatc tttaagagcg ataacgaatt
     2701 ggttgacaaa gtttggcaac atcaatttag ttgcttgtgg caagataatc ttacgcatgg
     2761 tttttccata agagataccc aagcttcggc tggcttccat ttggccaact ggaacggcct
     2821 gaataccacc acgaacgatt tcagcgatat aagcagccgc attgagtgag agggcaattg
     2881 ttccagctac aaagtcgtta attgggcttt gttggcctgt gatagactcg atgaagtttg
     2941 gaattcccca gaagatgaag gctgcaagaa tcatcaatgg aataccacga ataacgtcaa
     3001 cgaaaatctc agagatgacg cgaagagatt tgtatgggct aacgctaaac ataccgaaga
     3061 taattccgat gacaatggca atagcaaatg agataagagc tagagcaaga gtgataccaa
     3121 gaccgctaag gagttgtttg tagttgtttt gaagcaagcc ccagagcgtt gtttcgtcaa
     3181 cagtacttgt tgaagcagtt gaagattcgc tagctaggta tttgtcaaga atcttttgga
     3241 attcaccgtt tgctttaagg tttgcaagtc cgttgttgaa catttcaatc agttctggat
     3301 ttgctccttt tttaacggca aaggctgttt caccgattgg agttccagag attggagttt
     3361 tcaatttttg accttggctg atagaatatt tgagaacagg ttcatcatcc ataacggcat
     3421 caatggcacc agtgtttaaa ctgtcataca ttgaagaacc atcagcaaag gttttgattt
     3481 tgtaaccgta tttgctttga ttttctgtta ggaaggtttg agaagcagtt ccgtttttaa
     3541 caccgactgt ctttcctttt agatcttcat aagaagcaat attgcttgat tctttgacac
     3601 caagaatggt attagcagtg tagtatgatt ctgagaagtc aaaagttgcc ttacgagcat
     3661 ctgtgacaga cataccagca atgataccat cggcttgacc agcttggaca gcactgatag
     3721 cagcatcaaa accagggttg gtgatttcaa tttcaaaacc ttggtcttta gcgattgcct
     3781 taatcaattc catatcaata ccagtgtatt ggttgcttga attttggaaa acaaaaggtg
     3841 caaaagaaga atcgctggca atgatatatt tagccttaac aggaatagct tttaatcctg
     3901 cgagagtagt tgtagttggc actgctgaag atgatgaagc agtccatttc ttgataattt
     3961 tatcaagact accatctttt ttcatttcag ccaaggcttg gttaaattca gtaaccaggt
     4021 gttcgtattt acttcctttt ttcacaccga aagcaaaact tcctacagct tcaccatcca
     4081 tttcaatatg gaggtcttga ccttggttaa tggcatattc gataacaggt ttgtcatcca
     4141 tcatggcatc gatggcacca gcactcaagc tgttgttcat taaatcacca gtgtcaaatg
     4201 ttttaatagt aaagccgtat ttatctttga ttgtttcaag gaaacgttga gcggcagttc
     4261 cgtttttaac accaacggtt ttgccagtta attggtcgta cttgctaatt ttgtgtgact
     4321 ttgtagtagc aatgacaact tttgtatcat agtaagtatc agacatggtg aagacttttt
     4381 cacgttcttt agtctttgtc atccctgcca tgatagcgtc ggcttgccca gcttgaaccg
     4441 cattgactgc tgcgtcaaat ccaggatagg acatctgaat gttccagcct ttaatctcag
     4501 cgactttgtt aataatgtca acatcaattc ctttataagt ttgatctgaa tctttaaact
     4561 caaaaggtgc ataagcggta tcagaaacaa tcttaatcgt ttctgctttg gcaataccta
     4621 atgagaaaat tgggaataaa attagcaaaa atgctagaaa ttttttcttc atttttagtc
     4681 tccttttccg aatattctct cattatatca gaaaaagtaa aaaaaggcaa atttttatat
     4741 ttttcgtgtc agaaaatata acattgattt ttccttttct ttcttgaatt gctattaaaa
     4801 agtgctataa taatagtata tatagaagaa aagaggacgg ggatatgaag aacaaaagaa
     4861 tatttaaaga cttccaagct tcaaaaatga atttaaacat ttacacaagc tccttgttag
     4921 cctttgtttt tgtcttcata ggagagtttg tggcttatac tttatatggt attagtttgt
     4981 tagctctcat cggacttgct agaaattttg gagaggctgg tcaaaatctt gcaagctact
     5041 tgcagacctt gcatcagagc ttgacggata aaacaagtga ttttcgttta attttaggat
     5101 tactggcctt tggttttatt cttaacactg tgttcagatg gacaagaaaa gttgagaaaa
     5161 gacctattcg aaccttggga ttttatagag agaattgcct cagcaatctt ctgaaaggat
     5221 ttagtctagg cctggtactt tttcttctga ccttgttagg tttggtggtc ttaggtcaat
     5281 atcgtttgga atccattcac ttgaatcctt attctcttgc ctttgtcgtc tttactatcc
     5341 cattttggat tttacagggg acagcagaag aagtggtggc ccgtgcttgg ctacttcctc
     5401 aattggcctc aagaaccaat ctaaaactag ctattcttat atctagcctg ttctttaccc
     5461 tgcttcatat gggcaattct ggcctcaccc ctctatctct agtaaatctc tttttattcg
     5521 gagttgccat ggctctttac cttctcaaaa ctgatacagt ttggggtgtt gcaggtattc
     5581 atggtgcttg gaattttgct cagggtaatc tctttgggat tttagttagt ggtcaaccgt
     5641 caggaacgtc tctgatgacc tttttaccac aaggcaatca agattggcta tcaggtggtt
     5701 cttttggcat agaaggttcc attatgacaa gtctggtatt actactgctg attgtctatc
     5761 ttgctaataa attaaagaaa gaaaatgaaa ggatgtgact tcggtccgtc cttttcttcg
     5821 tgaaaatact ataagtatgc taaaatagga atagcacatg gagagaggat tcttatgatc
     5881 aatcacatta cagataatca atttaaacta gtatcaaaat atcaaccatc aggagatcaa
     5941 ccccaagcta tcgagcagtt ggtggataac attgaggggg gagaaaaagc tcagattctg
     6001 atgggggcga ctggaacagg gaagacctat actatgagtc aggtcatttc taaagtcaat
     6061 aaaccaactc tggttattgc ccacaataaa actctggctg gtcagctcta tggggagttt
     6121 aaggaatttt tccctgaaaa tgcagttgag tatttcgtat cctactatga ttattaccag
     6181 ccagaggcct atgtcccttc tagcgatacc tatattgaga aggatagttc tgtcaatgac
     6241 gagattgaca agcttcgcca ctcagctacc tcagcccttt tggagcgtaa tgatgttatt
     6301 gtcgtggcct cagtctcttg tatctatggt ttgggttcgc ccaaggaata cgctgatagt
     6361 gtcgttagtc tccgtcctgg tctagagatt tctcgtgata aactcttgaa tgacttggtc
     6421 gatattcagt ttgaacgtaa tgatattgat ttccaacgcg gaagatttcg cgttcgtggg
     6481 gatgtggtag agattttccc agcttcccga gatgaacatg cctttcgagt agaatttttt
     6541 ggagacgaaa ttgaccgtat ccgtgaggtt gaggctctga caggtcaggt attgggagag
     6601 gtggatcatt tggcgatttt cccagctact cactttgtga ccaatgacga ccatatggaa
     6661 gttgccgttg ccaagattca agcagaatta gaagagcagt tagctgtctt tgagaaggaa
     6721 ggtaaattgc ttgaagccca gcgcttgaaa caacggacag agtacgatat cgaaatgctg
     6781 cgcgagatgg gctatacaaa tggggttgaa aattattctc gccacatgga tggacgtagt
     6841 gaaggtgagc ctccttatac gcttctcgac tttttcccag atgatttttt gattatgatt
     6901 gacgagagtc atatgactat gggacaaata aaaggcatgt acaatggaga ccgttcgcgt
     6961 aaggaaatgc tagtaaatta tggtttccgt ttaccgtctg ccttggacaa tcgtcctctc
     7021 cgtcgtgagg agtttgaaag ccatgtgcat cagattgttt acgtatcagc gacacctggt
     7081 gactatgaaa atgaacagac tgagacggtg attgagcaaa tcattcgacc gacagggctt
     7141 ttggatcctg aggtggaagt ccgtccgact atgggacaga ttgatgatct cttaggtgaa
     7201 atcaatgccc gtgttgaaaa gaatgaacga acctttatca ccaccttgac caagaaaatg
     7261 gcagaggact tgaccgacta tttcaaggaa atgggcatca aggtcaagta catgcactcg
     7321 gatatcaaga ccttggaacg gacggagatt atccgtgatc tccgcttggg tgtctttgat
     7381 gtcttggttg gaatcaatct ccttcgtgaa gggattgacg ttcctgaggt tagcttggtt
     7441 gccattctcg atgctgacaa ggaaggtttc cttcgtaacg agcgtggact catccagacc
     7501 attgggcgtg ccgcccgtaa cagtgaaggt catgtcatca tgtatgcaga tacggttacc
     7561 cagtctatgc aacgtgctat cgatgaaact gcccgccgtc ggaaaattca gatggcctat
     7621 aatgaagagc atggtatcgt accacagaca atcaagaaag aaatccgtga cctgattgcc
     7681 gtgaccaagg cagttgctaa ggaagaggac aaggaagtcg acatcaatag cctcaacaaa
     7741 caagagcgca aagaactcgt caagaaacta gaaaaacaaa tgcaagaagc cgtcgaagtg
     7801 cttgactttg aactggcggc tcagatccgt gatatgatgt tggaagtcaa ggccttggat
     7861 taggggaata gtatgattta tttaagaaag ttaaagagag aagatttgat gtctttatgg
     7921 gaaatggctt attcacaact taatccagtt tggaaacagt atgatgctcc ctattatgat
     7981 gattatcagt atttttcaaa ttttaaagaa ttcgaactac aaaaatcaga atccatttta
     8041 agcaactcaa atcgccttgg tatttttgtt gatgataaac tagttgggac tgtttcgcgt
     8101 tattgggtat gtaaagaaac aagatggatg gaattgggaa ttggtattta tgataaaaaa
     8161 ttctggaaca ctggtattgg gaaagttgct atgttgcagt ggatagatag gacgtttcag
     8221 gattacttgg agttggagca tctgggtttg acaacttggt cagggaatct tggtatgatg
     8281 aaacttgctg aaaaattaag aatgaaaaaa gaagctcata ttccaaaagt tcgttattat
     8341 caaggtaaat attttgatag tattaaatat ggtattttga gagaagactg ggagaaaata
     8401 aatgacggtt attatcaaat caatggaaac tcctaaagag atagaaggta aatcccttgt
     8461 tcactggcaa atgtggagag aggcttatga tgaccttttg cctgcagaat ttcaggagac
     8521 aatgacatta gaaagatgtc gactctttag tcaaaagtat ccagaaaata cattgattgc
     8581 gataggtgat ctgaaggtag ttggttttat cagttatggt aactttcgtg atgagactat
     8641 tcaagctggt gaaattattg ctttatatgt tttaaaagac tattacggaa aaggcatagc
     8701 acaaaagtta atgaaagcag ctttgactgc tcttaatcat ttttctgaaa ttttcttatg
     8761 ggtattgaaa gataacaagc gcgccattgc tttctatcaa aaaatgggtt ttacttttga
     8821 tggacaagtg atggacaaga aaagatactt gaacttggaa agcctataaa ggaaaaacga
     8881 atggtattct attctaaaat aattttaaaa agtagaagct aatggcactg gtaccaagtc
     8941 tgaaaattta ataaattaga aagcgagtaa atttatgtcc cgttcccaat taacgatttt
     9001 aaccaatatt tgtctgattg aagacttaga aactcagcgc gtagtcatgc agtatcgctc
     9061 tcctgacact aatcgctggt caggttatgc ctttcctgga ggtcatgtag aaaatgatga
     9121 ggcttttgcg gagtctgtca ttcgtgaaat ctatgaagaa acagggttga ctatccaaaa
     9181 tcctcaactt gtcggcatta aaaattggcc actagataca ggtgggcgct acattgttat
     9241 ttgttataag gcgactgagt tctctggtac ccttcgctct tcagaagagg gagaagtttc
     9301 ttgggtgcaa aaagaccaga ttccaaactt ggatctggcc tatgatatgc tacctctgat
     9361 ggagatgatg gaagctccgg acaaatcaga gtttttctac cgtcatcgta cagaagacga
     9421 ttgggaaaag aaaattttct aatcctttac taaataaccg agctgctcca aggcctcctc
     9481 gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg tggtaatgga tgccatctgt
     9541 caattcagat agaggtctaa agtcagaatg ctcgacttgt tctagaaaat gttgcacatc
     9601 tctgcgacaa gacagtttaa gcaaggtttc aatttctcca taaacgggat ggtcaatcaa
     9661 ggtattctgg acatgcccac cattatcgac aatagcaagg agttcctgac cgatttcttc
     9721 aacttcatgt ttcactttga aaagtttgtg aacataagga ttggtatcaa tttgcttata
     9781 gatgtagcca cgattggtgg ataggatagg agcgccatcg gctctcaaaa ttgcaatgtc
     9841 ctgcacaatg acctgacgtg tgacatgaaa atgttccgcc aaactttggc cattaagggc
     9901 tttaggagct tctttcaaga gttggagcag ggcttgtttg cgatcttttg tcatagcttt
     9961 tccttttaac ggcgttttcg aagcacttta tagacagcta gtgctaatgt atagtctacc
    10021 atactatgga taattgtgcc aaatccaact agcacaaata gaacatagaa catgttttct
    10081 acattggtac ccgaagttgc gtaaaaaagg acacaggcta atacttcagc aagggcatga
    10141 acaacagcca aaacaaagtt gaaaacccag gaagattttg gtttatctag ggtatcgggg
    10201 aatttttgta ggtaaagagc tcctaaagca ccaaaagata tatgggaaaa agcccgaaaa
    10261 acgataacca tgggatagcc agccatcaaa aatccaaaac tagaggctag gatgacaaaa
    10321 actgccatca agggcgacaa gaacatggct ataaaaatag cgatgtggct ccccaaagta
    10381 taggaagcag gtggaatgac aatcttgaaa ggcataacaa ttggaatcaa aatcgcaata
    10441 gccgttaaaa gggctgtcat tgtcataaat tgtgtctttt tccgtgtatt cacaagaatc
    10501 tcctttttaa ctgcatatac actagtatgg tacaataaac cagacaataa agcaagaatt
    10561 tacttgggtt tatagatcat tttttagtta aaagttatag tagattgaaa ctagaatagt
    10621 ccacctctac ttctaaaaca ttgttagaaa tcgatttggc tgtcctgatc aatttgtcct
    10681 gttcttattt cgttttacta tagtaaagat ttcattaaaa agaaactgta tagagcaaaa
    10741 tctccaccct caggtttgaa agcggagatt gtttttattt tttcaaggtt tgtagtcgtg
    10801 gaacaatggc tagggttaga attgcagaaa tgaccaattc agcaattgaa tttgttgaga
    10861 taacggttgc cagaagaagt tggatatttc cgttataaac atttccaaat aggaagaaga
    10921 ttcctccaag gacaaagata gtatttgtca aggaaccaag agccccagct aaaatcagac
    10981 cagtcttgtt tttcatcagt ttatagacta agtaaggagt taaaccaatc aaaatacgtg
    11041 ggacaatggc aatgatagct gagtagatgt ttccgtttgg tacgaaggga gagaagaggt
    11101 agcttgtcgg tagaatcgta atcgtgttaa ccgtcaagct aagtaatccc atcaaaaatc
    11161 caagtgtaac cccaactcgt ggaccataaa taatgctggc aataatgaca ggaatatgaa
    11221 caatggtcgg tttgattgga aatggaaaaa ggttaaagat aagtgagctc agaaagtgta
    11281 tcacgagcat ggtagcaaaa aagatagcaa tgggtgcaat attagagcgt tttttcatcg
    11341 atagtttcct ttattctttc taaaataatt gtgaggtcag ctaaagctcc tcgtccgtgg
    11401 tctccacaag ctagtaggga ttccttagga gcaatcagct gatagccgta ggtttctaat
    11461 gttttcagat tattctgagt tactggatgg tcatacattt ttgtattcat agcaggagct
    11521 attagtttgg gaatatgact tggtagggct agagctgtac tggttaccat gttgtccgca
    11581 aatccgtgag ctagttttgc aatagtgtta gcagttgcag gtaccacgat aaataaatct
    11641 gctttttttc caagttcgat atgattgacc tgatcaggat agggttcttt catgacatcc
    11701 aagtggacag gattctgtga gagtacctgt agtgtcaaag gttggataaa ctctgtagca
    11761 gcctgagtca ttaagacagt gacttgatgg ccttgttttt ttagagaact gactaaatct
    11821 gccgacttat aagaggcgat tgaacccgtt acagccaaga gaatgtttgc catagttttc
    11881 ctttctaaga atgataggct tgaatttttt caaggaggag ttctgcaatt tcttctttag
    11941 tctggactgt ttgaagctga tttttctcaa caaatatagc tcggtgctga tctgctgaaa
    12001 tttgagtcag gtcattcgcg atgattaaat ctgcttgatt cttgataaga ctttttcgtg
    12061 caatgtcaac cagatgatct tcggtaacat caaccagcag tttgaaacca atcagatgaa
    12121 tagtaggatt ccattccttg actagggata tgattttggg tgtcttttta aggaacaaaa
    12181 cctgaacctc atcagttgaa gaaatcttgg tctgatgatt ctgcttgctt aaaaattctt
    12241 ttagattgga gctagcctga acttcctcaa gccctgtcat ataaacagga gtgtagtcag
    12301 aaacagccat tgagtggatc aagacctgat aatcctgaac acgttcttgc atttctatta
    12361 gaaggtcctt ggtattggta atttctcgaa tacttaggtt aggatgaggc tctggcttca
    12421 gagctcgttt tgtcgtaatt aaacaaactt catgccctgc agaaagcaaa gtctctgtga
    12481 taattttccc caagtgacct gtagaatggt tagtgataga gcggacgcta tcgatagctt
    12541 cactggtacc gcccgatgta actaaaattt tcatagcact attgtacaca aaaataagcg
    12601 gtaagtaaaa tgaaagtgat aaatttttgg taaaaacgaa gatttattat agtttcaaac
    12661 tataaagcca tataaaattt aagaaaggac tctaaaagtc ttaaaaacag agatatttac
    12721 gaacgtttag agagttttaa gatgttaaaa atcttgtttt gtgatataat gaattatcat
    12781 ataagaggtt agaggaattt tgaatgaaaa cagatattga aatcgcacag agtattgagt
    12841 tgaagccaat tgttgatgtt gtagagaaac ttggtatttc ttacgacgat ttggagttgt
    12901 acggaaagta caaggctaaa ctcagctttg ataaaattcg ggcagttgag agcaatccag
    12961 tcggtaaatt gatcttggtt actgccatca acccaacacc tgcaggtgaa ggaaagtcga
    13021 cgcttaccat tggtcttgcg gatgccttga acaagattgg caagaaaacc atgattgcta
    13081 tccgcgaacc gtctcttggt ccagtcatgg ggatcaaggg tggtgctgct ggtggtgggt
    13141 atgcacaagt tctgccaatg gaagacatca acctccactt tactggagat atgcatgcta
    13201 ttacaactgc caacaatgcc ctttctgcct tgattgacaa ccacttgcac caagggaatg
    13261 agctgggaat tgatcaacgt cgtatcctct ggaaacgcgt tgtggacttg aacgaccgtg
    13321 cgctccgcca tgtgactgtt ggtcttggtg gtcctctaaa cggtattcca cgtgaggatg
    13381 gttttgatat tacagttgct tcagaaatca tggcaattct ttgcttggca acggacatcg
    13441 aggacttgaa acgtcgtttg gcgaatatcg ttattggtta tcgctatgac cgtacgcctg
    13501 tttctgtagg tgatttgcag gttgagggtg ccttggcttt gattttgaag gatgctatta
    13561 agccaaactt ggttcagaca atttacggta cacctgcctt tgtacacggt ggtccatttg
    13621 ccaatatcgc tcatggctgt aactctgttt tggcgacgac aacagccctt cacttggctg
    13681 attacactgt tactgaagct ggttttggtg cggaccttgg tgctgagaaa ttccttgata
    13741 tcaagacacc aaacttgcca acatctccag atgcagttgt tattgtcgca acccttcgtg
    13801 cccttaagat gaatggtggt gtggctaaag acgctctgac tgaagaaaat gtagaggcag
    13861 ttcgtgcagg ttttgctaac ttgaaacgcc acgttgaaaa tatccgtaag ttcggtattc
    13921 cagcagttgt agctattaac gaatttgtat ctgatacaga agctgaaatt gcagtcttaa
    13981 aagaactctg tgcctcaatc gatgtaccag ttgaattggc tagtgtctgg gctgatggag
    14041 cagaaggtgg agtagcactt gccgaaacag ttgttaagac aattgctgaa aatccagcta
    14101 actataaacg tttgtatgat aatgaccttt ctgtccaaga aaagattgaa aaaattgtca
    14161 ctgaaatcta tcgtggtagc aaagtgaact ttgagaagaa atctcaaaca caaattgctc
    14221 aaatcgttca aaacggttgg gacaaattgc caatctgtat ggctaaaact caatacagtt
    14281 tctcagacaa tccaaatgcg cttggagcac cagaaaactt tgaaattacc attcgtgaat
    14341 tggtaccaaa attaggtgca ggcttcatcg ttgccttaac tggtgatgtt atgaccatgc
    14401 caggtcttcc aaaacgtcca gcagctctca acatggatgt tgaaagcgat ggaactgtac
    14461 taggcttgtt ctagtggatt gaaattgact ttaagtgagt ttggaaataa tatccaagct
    14521 cattttttct cagactgcaa gcagttcatc aataagattt atactcttcg aaaatctctt
    14581 caaactacgt cagcttcacc ttgccgtagg tatatgatac tgactctgtc agttctatcc
    14641 acaacctcaa aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
    14701 ttcattgagt ataagtagat agaaaagtta tatactatct attgaaaata ttataaatca
    14761 gatacaaaga caggtgaaac cttctgtgtt atactagaga tatgttagat ttgaaagaat
    14821 acggtatcgt catgtggccg gaggagaaag tcatttcttt ccgtgagaaa cttctcgctt
    14881 ggtatgatga aaacaaaaga gatttgcctt ggaggagaag taaaaatcct tatcacatct
    14941 gggtatctga aatcatgctt cagcagacca gggtggatac agttatccct tactacgaaa
    15001 gattcctgga ctggtttcca actgtcgaaa gtctggcaac tgcgcctgag gagagtttac
    15061 tgaaagcttg ggagggcttg ggctattatt ctcgagttcg caatatgcag gctgcagccc
    15121 agcagattat gactgacttt ggtggccaat ttccaaatac ctatgaagga atttccagct
    15181 tgaaagggat tggaccttac acagcaggag ccatttccag tattgctttt aacttgcctg
    15241 agccagctgt agatggtaat gtcatgcggg tcttggcgcg tctgtttgaa gtcaaccacg
    15301 atattgggat tccaagtaat cgaaaaattt ttcaggcaat gatggagatc ttgattaatc
    15361 cggatcgtcc gggtgatttt aatcaagcct tgatggactt agggtctgat attgagtctc
    15421 ctgtaaatcc cagacctgaa gaaagcccag tcaaggactt tagtgcggca tatcagaatg
    15481 gaaccatgga ccgttatcca attaaatctc ctaagaaaaa gccggttcct atttatctta
    15541 aagccttagt tgtgaaaaat tctcaaggac aatttttact tgaaaaaaat gaaagcgaaa
    15601 agctcttggc aggtttttgg catttcccct ttatagaagt tgataacttt tcgcaagaag
    15661 agcagtttga cctctttcat caggttgcgg aagaaagtgt gaactttggc cccagtccag
    15721 aagagagttt ccagcaggac tatgacctag atgttgattg gcttgatgtt tgttttgata
    15781 cagtccagca tgtttttagt catcgaaaat ggcatgtaca gattgtagca ggtcaggtga
    15841 gtgacttcca tgatttttca gatagggaag ttcgttggct ttcaccagaa gaattcaaga
    15901 attacccact tgccaaaccc caacaaaaaa tctggcaggc ttatgcacaa gccaacttag
    15961 acagtagcca agactagcta ttgtgtcttc tgactatttt ttggtataat agtagagaaa
    16021 aaggtgaaca tatgaaaaaa atactaattg tagatgatga gaaaccaatc tcggatatta
    16081 tcaagtttaa tatgaccaag gaaggttatg aagttgtaac tgcttttaat ggtcgtgaag
    16141 cgctagagca atttgaagca gagcaaccag atattattat tctggatttg atgcttccag
    16201 aaattgatgg tttagaagtt gctaagacca ttcgtaagac aagcagtgtg cccattctta
    16261 tgctttcagc caaagatagt gaatttgata aggttatcgg tttggaactt ggggcagatg
    16321 actatgtaac gaaacccttc tccaatcgtg agttgcaggc gcgtgttaaa gctcttctgc
    16381 gtcgttctca acctatgcca gtagatggtc aggaagcaga tagtaaacct caacctatcc
    16441 aaattgggga tttagaaatt gttccagacg cctacgtggc taaaaaatat ggcgaagaac
    16501 tagacttaac ccatcgtgaa tttgagcttt tgtatcattt agcatcgcat acaggtcaag
    16561 tcatcacgcg cgaacacttg cttgagactg tctggggtta tgactatttt ggtgatgtcc
    16621 gcacagttga tgtgactgta cgacgtctgc gtgagaagat tgaagatacg cccagccgac
    16681 cagagtatat cttgacgcgc cgtggtgtag ggtattacat gagaaataat gcttgattta
    16741 ctgaaacaaa ccatttttac cagagatttt atctttatcc tgattttgtt aggtttcatc
    16801 cttgttgtga ccctcttatt actggaaaat agacgtgata atattcagtt gaagcaaatc
    16861 aatcaaaagg ttaaagattt gattgcagga gattattcca aggttcttga tatgcaaggt
    16921 gggtctgaaa tcaccaatat taccaataat ttgaatgact tgtcggaggt tattcgtctc
    16981 actcaggaaa atctagaaca agagagtaag aggctaaata gtattctgtt ttatatgaca
    17041 gatggggttc ttgcgactaa ccgtcggggt cagattatca tgattaacga tacagccaag
    17101 aagcaactgg ggttggttaa ggaagatgtt ctgaatagaa gcattttgga attgctcaag
    17161 atagaagaaa actatgaatt gcgtgatttg attacccaaa gtccagaatt gttgctagat
    17221 tcccaagata tcaatggtga atatttgaac cttcgagttc gctttgcctt gatacgtcga
    17281 gagtctggct ttatttcagg tttggtggct gttttgcatg atacgacgga gcaggagaag
    17341 gaagaacgcg aacgaagact ctttgtttcc aatgttagcc atgagttacg gactcctctg
    17401 actagcgtaa aatcctatct tgaagccttg gatgaggggg ctttgtgtga aactgtagca
    17461 ccagacttta tcaaggtttc tcttgatgag accaaccgta tgatgcgcat ggtgacggat
    17521 ctcctccatc tttcacgtat tgataatgct accagtcacc tagatgtgga actgattaac
    17581 ttcactgctt ttattacctt tatcctcaat cgttttgaca agatgaaagg acaggaaaag
    17641 gagaaaaaat atgagttggt gagagattat cccatcaatt ctatctggat ggaaattgat
    17701 acagataaga tgacgcaggt tgtcgacaat attttaaata atgctattaa gtattcgcca
    17761 gatgggggta aaatcactgt cagaatgaag acaactgaag accagatgat tttatccatt
    17821 tctgaccacg gtttggggat tcctaagcag gatttaccac gtatctttga ccgtttctat
    17881 cgtgtggatc gtgctagaag tcgtgcacaa ggtggtacag gtctaggact gtctatcgct
    17941 aaagaaatta tcaaacaaca taagggcttt atttgggcca agagtgaata cggcaagggt
    18001 tcaaccttta ccattgtgct cccttatgat aaggatgcag tgaaagaaga agtatgggag
    18061 gatgaagtag aagactagaa tgagtgaaat aggctttaaa tacagtattt tagcgtcggg
    18121 ttccagtgga aattcttttt atctggaaac ctcaaaaaag aagcttttag tagatgcagg
    18181 cttgtctggc aagaaaatta ccagtctgct agctgaaatt aaccgtaagc cagaagacct
    18241 ggatgccatc ttgattaccc atgagcattc agatcatatc catggagtag gcgttttggc
    18301 tcgcaagtat ggtatggatc tttatgccaa tgaaaagacc tggcaagcta tggaaaatag
    18361 taaatatctt ggcaaggtgg attcttcgca aaagcatatt tttgaaatgg gtaaaaccaa
    18421 aacctttgga gatatcgaca tcgagagttt tggtgtaagc catgatgcag tcgcaccgca
    18481 gttctatcgc tttatgaagg atgataagag ttttgtcctt ttgacagata caggttatgt
    18541 cagtgaccgt atggcgggca ttgtcgaaaa tgcggatggc tatcttatcg aggccaacca
    18601 tgatgtagag attttgcgat caggttctta cgcttggcga ctcaaacaac gaatcctatc
    18661 tgaccttggt cacctttcta acgaggacgg tgctgaagct atgattcgga cgctaggaaa
    18721 tcgtactaag aagatttacc ttgggcattt atctaaggaa aacaatatca aggaactggc
    18781 tcatatgacc atggtcaatc agctggctca agctgatctg ggagtcggag tagactttaa
    18841 ggtttatgat acctcaccag ataccgcaac accattgaca gagatataga aagaacgctg
    18901 agaaggtgtt ctttttatat tgactgaaca cctaaaaagt aatacaatgg tgttaccatt
    18961 aaaaaaggga gcacaaaaga tgactactat tacattaaaa gtttctgaag ctgataaaac
    19021 atttatgaaa gcaatggcta agtttgaagg cgtttccctt tcggaactta ttcgcaccaa
    19081 aactcttgaa gccctagaag atgaatacga tgctcgtgtg gcagatttag cctatcaaga
    19141 gtatttagaa gacttggaaa aaggagttga acccattact tgggaagaaa tgatgcatga
    19201 tttaggcttg aaggatgaat aatttgtata aattagttcc aacaagacgt tttatcaagc
    19261 aattgaaaaa attggaccgt tatacgcaga agctaattac aaactattta caaaccaatg
    19321 ttttggaaga cccaagacga cacggaaagg ctttggttgg taatcgcgtt ggtcaatggc
    19381 gctatagaat tggtaattat cgagttatcg tacaaattgt agatgatgaa ttagtcgttg
    19441 ctactctaga agttggtcat cggagagata tttattaaat taaagctgag taataacagt
    19501 atagaaagta aggagagtaa aaatttgaag aaaaaatggt tttttgcaga ttattatgac
    19561 acaacaatta ttttacttgc tttaatctct gttattctgg tattacttgg atttgctgag
    19621 atgattgatt tggacaatcc gccttatagt attattgatt tagtaatctg gggtgttttt
    19681 gtaattgatt atagttggcg cttttttacg actaaaagaa aatggcgctt tattcttgaa
    19741 aatatttttg atttattggc tattctccct ttaaatgcta tttttacagt gtttcgatta
    19801 gggcgtatct ttcgtttagc taaactaaca aaattactga aactgactcg tttacttaga
    19861 ataattggac ttacaggtaa attagaaaga aaaattagta gattcttacg gacaaatggc
    19921 ctgatttata tcttgtatgt taatatcttt attgttctag tagggagttc gattttatcc
    19981 gttgttgaag aaaaatcctt ctcagatagt ctttggtggg ctcttgtgac agtaactact
    20041 gttggatatg gggatattgt tcctgcttcc atttttggga aatggctagc agttttactg
    20101 atgcttgtcg gtattggaac aatagggatg ttaacaagtg ccttgacgaa cttttttgta
    20161 aaggataatc cagatgaaca gataaaactt gataaactca aagatgaatt atcgagccaa
    20221 agaatattac tagagaaaca atctaaaaag atagaagaac tacataaaat gatacaagat
    20281 ttgattgaaa aaacataata aaaataaaga tgagacaaag tttgagctga ggagaaatca
    20341 agtaagtttt gacacaatag aacgcatatt atcaggtata aaaacttgat actatgcgtt
    20401 ttatagagaa ataaaataaa atctgaacaa atcaattagg aatttaaagc attttataac
    20461 aacgttttag agtgatgggg tgctatttca acttcaacct actataatac agaaaaaaac
    20521 aactccctga tgattcaagg agttgtctat agttaaatta gtttttagaa gcttcttgga
    20581 attctggatt tttccatgct tcgtcaataa tagcttgcaa ttctttagca gatgcttgca
    20641 ttttttgagt ttctgcatcg ttcaatggaa tgtttactgg acgaacgata ccatgtgcac
    20701 caacaacagc tggttgaccg ataaagacat tctcaactcc gtattgacct tcttggaata
    20761 ctgaaagtgg aagtactgcg ttttcatcgt caaggattgc tttagtgata cgagcaaggg
    20821 ctactgcgat accgtagtat gttgcacctt ttttgttgat gattgtgtag gctgcatcac
    20881 gaacaccttc gaacaattca atcaattcag cttcttgaac attttgagtg tctttaagga
    20941 attcttcaag gtttacacca gcgatgttag cgtgtgacca aacagcgaac tcagagtcac
    21001 cgtgttcacc catgatgtag gcgtgcactg aacgagcatc cacatccaat ttttcagcaa
    21061 gtgcttgacg gaaacgagct gagtcaagtg aagtacctga accgataacg cgttctttag
    21121 ggaaaccaga gaatttccaa gttgagtaag tcaaaacgtc aactgggtta gcagcaacaa
    21181 ggaagatacc tttgaaacca gattcaacaa cttgagttac gattgatttg ttgatagcaa
    21241 ggtttttacc tacaaggtca agacgagttt cacctggttt ttgaggtgca cctgcagtga
    21301 tcacaacaag gtcagcgtct gcacagtcag agtattgagc tgcatagatt tttttaggtg
    21361 aagtgaaggc aagggcgtga ctaaggtcaa gcgcatcacc aacagctttt tcatgcaatt
    21421 gtggaatttc gataattcca agctcttgtg caattccttg gttaacaagt gcaaaagcgt
    21481 aagatgaacc tacagcacca tcaccgacaa ggataacttt tttgtgttgt ttagttgaag
    21541 tcattgtttt aaacatctcc ttaattttat taggggattt tccctagaca acttcattct
    21601 atcactttta aaaaactttg tcacgaatat gccttatagt tctcgatgta aacgttttag
    21661 tggtttagag gctgaaatag atgggaattt atggtataat gttgttactt actaattgtg
    21721 aaatgaggca tttattaatg caggataaaa atttagtgaa tgtcaatctg acaaaggaga
    21781 tgaaggcaag ttttatcgac tacgccatga gtgttatcgt agcgcgagct cttcctgatg
    21841 ttcgagatgg cttaaaacct gttcaccgtc gcattctcta cggaatgaat gaattgggtg
    21901 tgaccccaga caaaccccat aaaaaatctg ctcgtattac aggggatgtc atgggtaaat
    21961 atcacccaca cggggattcc tctatttatg aagccatggt ccgtatggct caatggtgga
    22021 gctaccgtta catgcttgta gatggtcatg ggaattttgg ttccatggat ggagatagtg
    22081 ctgccgctca acgttatacc gaggcacgta tgagcaagat tgctctggaa atgcttcgtg
    22141 atatcaacaa aaatacagtt gatttcgttg ataactatga tgccaatgaa cgggaaccct
    22201 tggtcttgcc agcgcgtttt ccaaaccttt tggttaatgg agcaactggt atcgcggttg
    22261 ggatggcaac caatattcca cctcataatc tgggtgaaac cattgatgca gtgaagttgg
    22321 tcatggataa tcctgaagtg actaccaagg acttgatgga agtcttgcct ggaccagatt
    22381 ttccaactgg tgctcttgtc atggggaaat caggtatcca taaggcttat gaaacaggta
    22441 aaggttcgat tgtcctacgt tctcgtacag agattgaaac gactaagact ggtcgtgagc
    22501 gcatcgttgt aacagaattt ccttacatgg tcaataaaac caaggtgcat gagcatattg
    22561 ttcgcttggt tcaggaaaaa cgcattgagg gtatcacagc agtacgtgat gagtcaaacc
    22621 gtgaaggtgt tcgatttgtt attgaagtca agcgcgacgc ctcagccaat gttattctca
    22681 ataacctctt caaaatgacc caaatgcaaa ccaattttgg tttcaatatg ctcgctatcc
    22741 aaaatggtat accgaaaatt ttgtctcttc gtcagatttt ggatgcttat atcgagcacc
    22801 aaaaagaagt ggttgttcgt cgtacacgtt ttgataagga aaaagcggaa gcgcgcgctc
    22861 atatcttaga aggtctcttg attgcgctag accatatcga cgaagtgatt cgtatcatcc
    22921 gtgctagtga aacggatgcg gaagctcaag ctgagttgat gagcaagttt aagctttctg
    22981 aacgtcaaag tcaagctatc cttgatatgc gtcttcgtcg tttgacaggt ttggaacgcg
    23041 ataagattca atctgagtat gatgacctct tggctctgat tgcggattta gcagatattc
    23101 ttgctaagcc tgaacgtgtt tctcaaatta tcaaagacga attggatgaa gttaaacgta
    23161 aattttctga taaacgccgt acagagttga tggttggaca gattttgagt ctcgaggatg
    23221 aggacttgat tgaagaatcg gatgtcttga ttaccctttc taacagaggc tacattaagc
    23281 gtttggatca ggacgagttc actgctcaaa aacgtggggg tcgtggtgtc caaggaacgg
    23341 gagtgaaaga tgatgacttt gttcgtgagt tagtgtcaac tagcacacat gatcatctgc
    23401 tcttcttcac aaacaaggga cgtgtctatc gtcttaaagg ttatgaaatt cctgagtatg
    23461 gtcggactgc caaagggcta ccagtagtca atctcttgaa attggatgaa gacgaaagta
    23521 ttcagacggt tatcaatgtt gagtctgatc gcagtgatga tgcttatctc ttctttacaa
    23581 cccgtcacgg tattgtgaag agaactagtg ttaaggagtt tgccaatatt cgtcaaaatg
    23641 gtctcaaagc gctgaattta aaggatgaag atgagttaat caatgtcttg ttggcagaag
    23701 gagatatgga tattatcatt ggtaccaagt ttggttatgc agttcgcttt aatcaatcag
    23761 ccgttcgtgg tatgagccgt atcgccactg gtgtgaaagg tgttaacctt cgtgaaggag
    23821 acacagttgt tggtgccagc ttgattactg atcaagatga agttcttatt atcacagaaa
    23881 aaggatatgg taagcgtaca gtcgctactg aatacccaac aaaaggtcgt ggtggtaagg
    23941 gaatgcagac agctaaaatt accgaaaaaa atggcttgct ggccggtctt atgactgttc
    24001 aaggggatga ggatttgatg attatcactg atacaggtgt catgattcga accaatcttg
    24061 ccaatatttc acaaacagga cgtgcaacta tgggagttaa agtaatgcgc ctggatcaag
    24121 atgctcagat agtgactttc acaacggttg cggtggcaga aaaagaagaa gttgggacag
    24181 aaaacgaaac agaaggtgaa gcataatgtc tcaaaaaaat aataaaaaga aaaacaagcg
    24241 aaaaaatctg ctgacaaata tcctagcagg atttctgata ttactgtcac tggctttgat
    24301 ttttaatact caaattcgaa atattttcat agtctggaat accaataagt atcaagttag
    24361 ccaggtatca aaagaaaaat tagaagaaaa tcaggataca gaaggcaatt ttgactttga
    24421 ttctgtcaaa gctatctctt cggaagctgt tctaacttct caatgggatg ctcaaaaatt
    24481 accagttatt gggggaattg caattcctga attggaaatg aatttgccga tttttaaagg
    24541 acttgataat gttaatctct tctacggagc tggtacaatg aaacgcgagc aagtaatggg
    24601 agaaggaaat tatagtctag ctagtcacca tatctttggt gttgataatg ctaataaaat
    24661 gttattttct cctttagata atgctaaaaa tggcatgaag atttatctaa ccgataaaaa
    24721 taaagtttat acttatgaaa tacgtgaagt caaacgtgtg acaccggatc gtgttgatga
    24781 agttgatgat agagatgggg tcaatgaaat cacattagta acctgtgaag accttgctgc
    24841 tacagaacgt attattgtca aaggtgattt gaaagaaaca aaagattatt cacaaacatc
    24901 tgatgaaatc ctaacagctt tcaatcaacc atataaacaa ttttattaat acaaatcagt
    24961 gaaatcatgg atttcactga ttttttaaga ttttcataaa aatatagtaa aatgaaataa
    25021 gaataggacg aattgttcag gacaatcaaa tcgatttcta acaatgtttt agaagtagag
    25081 gtgtactatt ctagtttcaa tctactataa acttttatga aatacagaaa acgcttccta
    25141 aaacctaaag tttgtgatat aattatcaag aaaaaagatt taggagttta ttatgatttc
    25201 ttcagaattt atctcaaaga ttgaatttgc ttgcaataag aaagaaagtc tttatagtca
    25261 aagcaaattt aagtatgcga ttcgttcgat gttcgcaggt gcatttttaa ccttcagtac
    25321 tgctgcaggt gcagttgggg ctgacttgat taataaaatt gcaccaggta gtggacgctt
    25381 cctctttcca ttcgtttttg cttggggctt ggcctacatt gtttttttga atgccgagtt
    25441 ggtcacttca aacatgatgt tcttgactgc tggtagtttc ttaaaaaaaa tctcttggag
    25501 aaaaacagct gagattttac tatactgtac cttgttcaac cttatcggag ccttgatagc
    25561 agggtggggc tttgctcatt cggcagccta tgcgaatctg acacacgata gtttcatctc
    25621 aggtgttgtt gagatgaagt taggccgctc aaatgaattg gtcttgcttg aggcgatttt
    25681 ggcaaatatt ttcgtaaata ttgcgattct gtcatttatt ttggtcaaag atggtggtgc
    25741 caaactttgg cttgtgttgt cagctattta catgtttgta ttcttaacaa acgagcacat
    25801 tgcggcgaac tttgcttctt tcgcgattgt gaaattcagt gttgctgcgg attcaattgc
    25861 caacttcggt gttggaaata tgcttcgcca ctggggtgtg actttcatcg gaaactttat
    25921 cggaggaggc ctcttgatgg gtcttccata tgctttcctc aataaaaacg aagatactta
    25981 tgtagattaa gaaaatgagc acgattgagt cgtgcttttt tcattttcaa aataaggtaa
    26041 tagctatttc ttatatcaaa atatagaaaa ctgatatttg taaactataa ctcaaggtgc
    26101 tacaatatcc ttaataaaat gatatggagg tcaccttatg acttgtgatt ttaaatctga
    26161 aactctacaa ctacatgctg gtcaagttgt ggctccagct actaagtctc gtgcagtgcc
    26221 gatttatcaa acaacatttt ttgtttttga tgacacgtag gaaggtgccg atctgtttgc
    26281 cttgaggaaa ccagggaaca tttatactcg tatcaccaat cctacaacag ctgcccttga
    26341 aggtggtgtt gaagcgctag caacagcatc aggtatgact gcagtgactt atacgatttt
    26401 ggcgcttgcc catgctggtg accatgtagt ggctgcttcg actatttacg gtggaacctt
    26461 caatcttttg aaagaacccc ttcctcgtta tggtatcaca acaacctttg tcgatgttga
    26521 taatttggag gaagtagaag cagctatcaa agacaatacc aagcttgtct tgattgaaac
    26581 cttgggtaac cccttgatta atattccaga cctggaaaaa ctggcagaga ttgctcataa
    26641 acatcaaatc ccacttgtgt cagacaatac ttttgcaata ccttatttga ttaacgtctt
    26701 ctctcatggc gttgacattg ccattcactc tgcgactaag tttatcggtg ggcatggtac
    26761 aactattgga ggaataattg tcgatagtgg tcgttttgac tggacggctt cagggaaatt
    26821 ccctcaattt gttgacgagg gttcaagctg ccacaatttg agctatattc gtgatgtggg
    26881 tgcagcaacc tttattatag ctgttcgagt tcaattgctt cgtgatacag gtgcagtctt
    26941 gtcaccattc aatgctttcc tcttgctaca aagacttgaa actctttcac ttcgtgtgga
    27001 acgccatgta caaaatgctg agacaattgt tgattttctt gtcaaccatc ctaaggtaga
    27061 aaaggtaaat tatccaaaac ttgcagatag tccttatcat gccttggctg agaaatactt
    27121 gccaaaaggt gtcggttcaa tctttacctt ccacgtcaaa ggtgacgagg aagaagcacg
    27181 caaggtcatt gatcatttag aaatcttttc tgaccttgca aacgcggcag atgctaaatc
    27241 gcttgttgtc catccagcaa caaccactca cggtcaattg tcagaaaaag acctagaagc
    27301 agcaggtgtc acaccaaacc aaattcgtct gtcaatcggt cttgaaaatg tagaagattt
    27361 gattgaagac ttacgcttgg ccttgggaaa aatttaaagt aaaagaagat aaacagtggg
    27421 ttttgactca ctgtttttga ttttccctca ggcatgatat aatggttaca gaagtctaga
    27481 aagaggaatg taatgaacga aatcaaatgt cccaactgtg gggaagtctt tacagtaaat
    27541 gaaagccagt atgctgaact tttgtcccaa gtgagaacgg cagagtttga taaggaacta
    27601 cacgatagga tgaggcagga actggccttg gctgagcaaa aggctatgaa tgagcaacag
    27661 actaaactgg ctcagaagga tcaagaaatt gcgcaattgc agagtcaaat ccaaaacttt
    27721 gatacagaaa aagaattggc caagaaagaa gttgaacaga caagccatca ggccttattg
    27781 gctaaggaca aggaagtaca ggctttggag aaccaattgg ccactttgcg tttggagcat
    27841 gaaaatcaac tgcaaaagac cctttctgac ctagaaaaag aacgcaatca ggtcaaaaat
    27901 cagctcctac tgcaagaaaa ggaaaatgag ttgtctttgg cttctgttaa gcaaaactac
    27961 gaagcccagc tcaaagcagc cagtgaacaa gtcgagtttt ataagaattt taaggctcaa
    28021 caatctacaa aagcgattgg ggaaagccta gaacagtatg cagagagtga gtttaacaag
    28081 gtccgtagtt tcgcctttcc aaatgcttac tttgagaagg ataacaaggt ctcttcgcgt
    28141 gggtctaaag gggactttat cttccgtgag tgtgatgaaa atggagttga aatcatttct
    28201 atcatgtttg agatgaaaaa cgaagcggac ggaacagaga agaagcacaa gaatgcagat
    28261 ttttacaagg aattggacaa ggaccgtcgg gagaagaact gtgagtatgc cgttttggtg
    28321 accatgcttg aggccgataa tgactacttt aacacaggga ttgttgacgt cagccacgag
    28381 tatgaaaaaa tgtatgttgt tcgtcctcaa ttctttatcc agttgattgg tctcttacgt
    28441 aatgcggcgc taaattccct aaaatacaag caggagttgg ccttggttcg cgagcaaaat
    28501 attgacatta cgcattttga ggaagatttg gatgccttta agctagcttt tgctaagaac
    28561 tataattcag cttcgactaa ctttggaaaa gctattgatg aaatcgacaa ggccatcaaa
    28621 cgcatggaag aggttaagaa attcctgact acatctgaaa accaactccg tctagctaac
    28681 aacaaattgg aagatgtctc tgttaaaaaa ttgacccgga aaaatccaac aatgaaagcg
    28741 aagttcgaag cattgaaggg ggagtagaaa gcaaaaatga acggtattat caacttaaaa
    28801 aaagaagcag gaatgacctc gcatgatgcg gtttttaaac tgcgtaagat tttgggaacc
    28861 aagaaaattg gtcatggcgg aaccttggat ccggatgtgg tgggtgtttt gccgattgcg
    28921 gttggcaagg cgacacgcat ggtcgagttt atgcaggacg agggtaagat ctatgagggg
    28981 gaaatcactc tgggctattc cacgacgact gaggatgcta gtggggaagt ggtcgcagaa
    29041 acccctgttt tgtctccctt ggatgaaaag cttgttgatg aagcgattgc tagcttgact
    29101 gggcctatta cccagattcc ccctatgtat tcggcagtta aggttaatgg tcgcaagctc
    29161 tatgagtatg cgcgtgctgg tcaggaagtg gagcgtccag aacgtcaggt gaccatttat
    29221 caatttgagc gaacaagtcc gatttcttat gatggccaac ttgcccgatt cacttttcgt
    29281 gtaaaatgca gtaaagggac ttacatccgt actttgtcag ttgatttggg tgaaaagctt
    29341 ggttatgcgg ctcatatgtc ccatttgact cgtactagtg ctgctggctt acaattagaa
    29401 gacgctcttg ccttggagga aattgctgaa aaagtagagg ctgggcaatt agattttctc
    29461 catcctttag agattgggac aggtgacctt gtcaaagttt tcctaactcc agaagatgct
    29521 acagaagttc gctttggtcg ttttattgag ctagaccaaa cggacaaaga actggctgcc
    29581 tttgaagatg ataaattgtt agccattcta gaaaaacggg gcaatctcta taagccaagg
    29641 aaggttttta gctagatcgt ttaggaataa aaatcgggtg atagataaca attgcttgat
    29701 aaaaccccat actaaatagt agaatggttt tgggaattat aatattccaa ttgttgcgag
    29761 ttgtaggtac tcaaataatc tatatagaaa tttagaggtg tgaaatgaag caatttaaaa
    29821 ttctttcaga taaatattta gagtccatta caggttctgg tgggaactta ggcccaggat
    29881 ttggtgtgat aattccatga tgcgaaatga gtttcgagaa agggtggagc aacttcttca
    29941 acaaaaagaa ataaatgaaa atagtgagtt gagtcacctg tttcgtcttg ctatacaaaa
    30001 tttagacaga aatgaaaaac accaatcggt catggccaat ttgagtcaag ggttgtcact
    30061 ttacctcatg acgcatcatt accaggcacc taagtctgtc attgatttta gtttatggat
    30121 tgccaaagct cctagccagg aaagagggag gctggctttc ttgcagatgc ttgctcaaat
    30181 cctacagggc tttcgttaaa actgtcgaac atcagaggga agactctggt gttttttgct
    30241 gatgagacta taaattttgt aaaaaatgtg atagaataga cgacggataa aataacggag
    30301 gatagcatgc aaaatagacc aatcattatt ggagtgacag gtggttctgg tggtggtaaa
    30361 accagtgttt caagagccat tttatcgcat tttcctgatg aaaagatttc catgattgag
    30421 catgattcat actacaagga tcagtctcat ttgacctttg aagagcgtgt caaaaccaac
    30481 tatgaccatc cttttgcctt tgatacagac ttgatgatcg agcagattaa ggaattgttg
    30541 gcagggcgtc cggtggacat cccgacctac gactatacag agcatacacg gagtagcaag
    30601 acctatcgtc aggagcctca agatgtcttt atcgttgagg gcattttggt cttggaggac
    30661 aagcgtctgc gcgatttgat ggatatcaag atttttgtgg atacggatga cgatgtgcgc
    30721 attattcgtc gtatcaagcg tgatatggag gagcgtggcc gtagccttga tagcgttatt
    30781 aaccagtact taggtgtggt caaaccaatg taccaccagt ttatcgagtc aactaagcgt
    30841 tatgctgata tcgtcattcc tgaaggggtt agcaataccg tggctatcga cctgttgacg
    30901 accaagattg caaagatttt ggaagaagct cgaaacagca aataatcaca tgtggaggcc
    30961 ttgcctcctt tttctatttt tccctcataa tggtacataa atggagattt ttaggcatat
    31021 ttttggtata ataataccca tgaaagagca agtaaatgaa tagtaggtgg agatggaaaa
    31081 gtatttatcg gtaacaactt tgaccaagta tctgaaaatg aaattcgata aagacccata
    31141 cttggaacgg gtctatttaa ctggtcaagt ttccaacttt cgtaaacgac ctactcacca
    31201 atatttctcc ctaaaggatg accatgcagt tattcaagcg accatctggt ctgggattta
    31261 tcagaaatta gggtttgacc tggaagaagg aatgaagatc aatgtgattg ggcgtgtaca
    31321 ggtttatgaa ccaagtggta gctactccat catcattgaa aaagctgagc ctgatggggt
    31381 tggggcgctt gcgattcagt ttgaacaact taagaaaaaa ttgacagaag aaggcctgtt
    31441 tcaagaacgc ttcaagcaag ctctacccca attttctaag agaattgggg tagtaaccag
    31501 ccgtagtgga gccgttattc gagatattat cacgaccgtc agcaggcgat tcccaggtgt
    31561 tgacatcctt ctttatccga ccaaggttca aggtgaaggg gctgcggagg aaattgctag
    31621 aaatattgcg cgtgctaatc aacgggatga tttggatttg ctcattattg gtcgtggagg
    31681 tggttctatt gaggatctct gggcctttaa cgaagaaatt gtggtacgag ctatttttga
    31741 atctcgtttg ccagttatct ctagtgtggg gcatgagacg gatgtgacct tggcagattt
    31801 tgtggcagat cgacgcgctg caacgccaac agcggcggct gaactggcaa cacctgtgac
    31861 caagttggat gtattagctc atttgcaaaa tcaggaaaaa cggatggcaa cggcagtccg
    31921 aaatgttcta tctaagaaac aagaggcttt gaaaaaatgc agtcagtctg ttatctttag
    31981 acaacctgag cgcttgtatg acggttattt gcaacgcttg gaccaactgc aactgcgttt
    32041 gaaacaaagt ttgcgaactc ggatttctga taacaaacaa ttagttcaag caagaactca
    32101 tcaattagta caattatcac ctgttaccaa aatccaacgc tatcaagacc gtttaggaca
    32161 gttggacaag ctcttaggta gccaaatggc gttagtttat gacgccaagg ttgctgaggc
    32221 caagcgactt tcggaagctt tgctcatgtt ggatactagc cgaatcgtgg cgcgtggtta
    32281 tgctattgtc aaaaaagaag agtccattgt agattcggtt gagagtttga agaaaaaaga
    32341 ccaagtaacg cttttgatgc gagatggtca agtagaatta gaggttaaag atgtcaaaac
    32401 aaaagaaatt tgaggaaaat ctagcagaac tggaaaccat tgtccaaagt ttggaaaatg
    32461 gtgaaattgc tctggaagat gcgattactg cctttcaaaa gggcatggtc ttgtcaaaag
    32521 agctccaagc tacgctggac aaggctgaaa agaccttggt caaggtcatg caagaagacg
    32581 gaacagaaag tgattttgaa tgaaaaagca agaaaaatta gctcttgtcg agtcggcttt
    32641 ggaagatttt tatggagacc agcagtttgc ctctagttta cgggagtctg ttctctattc
    32701 tattcatgct ggtggcaagc gtattcggcc ttttctcttg ttagaagttc tggaatcctt
    32761 gcaggttgcc atcaaacctg ctcacgcgca ggtagctact gccttggaga tgattcatac
    32821 agggagcttg attcacgatg accttcctgc tatggatgat gacgattatc gaagagggcg
    32881 gttaaccaat cacaagaaat tcggtgaagc tatggccatt ttggctggag atgccttatt
    32941 cttagaccca tatgccttga ttgcgcaggc agatttgcca agtcagatca aggtggactt
    33001 gattgccaac ttatcccttg cttcaggtag tctgggtatg gtggcagggc aagttttgga
    33061 tatggagggc gaacaccagc acttgtctct ggaagaactt cagactattc atgccaataa
    33121 gactgggaag ttactagcct atcccttcca agcggcagct attatagctg aattgtcacc
    33181 tgaaatgcag gtgaagctga aaactgtggg tgaattgatt ggacttgctt ttcaagtcag
    33241 agatgatgta ctggatgtga cagctagttt tgaggaaatc ggcaagacac ctcaaaagga
    33301 tctgcaggca gaaaaatcaa cctatcctgc cttgttgggc ttggaagagt ccattgcctt
    33361 ttgtaaccaa accctggatc aagctaatga aaaattagaa gagattgccc agcagcttcc
    33421 ctttgaaaca gaatcgattg taagtgtagt agaaagtttg agaatcaatg gctaaggaaa
    33481 gagtggatgt actagcttat aaacaggggt tgtttgaaac gagagagcag gccaagcgag
    33541 gtgtgatggc tggtctagtc gtagcagtcc ttaatggaga acggtttgac aagccaggag
    33601 agaaaattcc agatgacacc gaattaaaac tcaaggggga gaaactcaag tatgtcagcc
    33661 gtggtggttt gaaactggaa aaggccttgc aggtctttga tttgtcggtg gatggcgcga
    33721 ctacgattga tatcggggcc tctactggag gttttaccga tgtcatgcta cagaatagtg
    33781 ccaagttggt ctttgcagtc gatgttggta ccaatcagtt ggcttggaaa ttacgccaag
    33841 acccacgagt tgtcagcatg gagcagttca attttcgcta tgctgaaaag actgatttcg
    33901 agcaggagcc gagctttgcc agtattgatg tgagtttcat ttcccttagt ctgattttgc
    33961 cagccttgca ccgtgtcttg gctgatcaag gtcaggtggt agcacttgtc aaacctcagt
    34021 ttgaggcagg acgtgagcag attgggaaaa atggaattat tcgagatgct aagattcatc
    34081 agaatgtcct tgaatctgta acagctatgg cagtagaggc aggtttttca gtccttggct
    34141 tggacttttc tcccatccaa ggtggacatg gaaatattga atttttagcg tatttgaaaa
    34201 aagaaaagtc agcaagcaat cagattcttg ctgagattaa agaagcagta gagagggcgc
    34261 atagtcaatt taaaaatgaa taaaaaagaa agacttgaaa aaattagaag attggtgaca
    34321 gattatcaaa tcggcacgca agaagaaatt gtagaacatt tgaaagaagc aggtatcact
    34381 gccactcagg cgacggtatc ccgagatatc aaagagttag gtattgtcaa aattcctttg
    34441 agagacaaca cctatgtcta cgaattgcca aaatcaatcg taaaaagtct gcaactggct
    34501 gaagacaata tcgaatcggc tgaattgatg gataagatga tcaatctcca agttattcca
    34561 ggaaatacgg cttttgtaaa agctcagtta atcgagactt ttgcagacaa gatttttagc
    34621 tgtttgactg atgatagctc gattttagtc attgccagaa gtggaagtct agcagaggaa
    34681 atctttgaac aagtaaaaaa ttggtaggtc tatatgttac ttgaaatttc gataaaaaac
    34741 tttgccatta ttgaggctat ttccctcaat tttgaaaagg ggatgactgt cctgactggt
    34801 gaaacgggtg cagggaagtc gattatcatt gatgccatga atatgatgtt gggagctcgt
    34861 gcgacgacag atgttattcg tcatggtgca ccaaaggcag agattgaggg gcttttctca
    34921 gttgagaata gtcgtctttt acaggaaatt tttgatgagc aaggtttaga attaggtgat
    34981 gaaattatca tccgtcggga aatcttgcaa aatggtcgta gtatcagccg tgtaaatggt
    35041 cagatggtta atctgtctgt tttgcgaacc attgggcaac atcttgtaga tattcatggt
    35101 cagcatgacc atgaggagtt aatgcgtccc caactgcata tccagatgtt ggatgaattt
    35161 ggtgatgccg ctttttggga cttgaaagaa acctatcaaa cgagttttga tgcctatcgg
    35221 aaaatgcgca agcaggttct ggaagtcaag aaaaaccaac aggaacacaa ggcacgtatc
    35281 gaaatgttgg aatttcaaat ggcagagatt gaggcagcaa acttgcaggc tggagaagac
    35341 ttggatctca atcaagagcg agataaactc ctcaaccaca aaaatattgc ggatacactg
    35401 accaatgcct acagtatgtt ggacaatgaa gatttttcaa gtctggccaa tgttcgttca
    35461 gccatgaatg acatggaaag tgtcgaagag tatgaccctg aataccgtga aatttcaagc
    35521 tctctgtctg agacctacta tgttttagaa gacattagca aacgtttgga agctatcatt
    35581 gaggaccttg attttgatgg caatcgcctc atgcaggttg agaatcgttt ggacctcctt
    35641 catactatta ctcgtaagta tggtgggact gttgatgatg ttttgcttta ttttgccaag
    35701 attacggaag aatacaatct cttgacaggc aataatcttt cgtctgagga catggaagca
    35761 gagcttaaga agttggaagt caatcttgtc aatttggcag gtcaacttgc ttctgctcgt
    35821 cataatttgg ctcagcaact cgaagctgag attaaacaag aactgcaaga tctttatatg
    35881 gaaaaagccc agtttcaggt tcgttttagt aagggaaaat tcagtcgtga gggaaatgaa
    35941 atggttgagt tttatatttc aaccaaccct ggagaagact ttaaaccctt ggttaaggtt
    36001 gcttctggag gggaattatc tcgtctcatg ttagccatta agtctgcctt ttcacgtaaa
    36061 gaaggcaaga ctagcattgt ctttgatgaa gtggatacgg gagtttcagg tcgtgttgct
    36121 caagctattg ctcagaaaat tcataaaatt ggtcagcatg gtcaggtttt ggctatctcc
    36181 catttgccac aagtaattgc gattgcagat tatcaattct ttattgagaa gattagtaat
    36241 gaccattcaa cggtttcgac tgttcgtctc ttgacggtcg aagagcgagt ggaggaagtt
    36301 gccaagatgt tggcaggtga tgatgtgaca gaagcagccc tgacgcaagc cagagaattg
    36361 ttgagaaaca gggagaaata agatgacaga ttattatgta attggagatg ttcacggaaa
    36421 agctgggatg ctggaagacc ttcttaaaac ctgggatggt cagacccagt tgctctttct
    36481 aggtgatttg attgacagag gtgaggatag tcaccgtgtt cttgaaatgg tcaaggactt
    36541 ggtggacaat caaggggcta tctgtttgtc tggaaaccac gagtatatgt ttttgacttg
    36601 gctagatgac ccagaagaaa gttatgacca ttatcgtcgc aatggtggag atacaaccat
    36661 taactctatc ctaggtcgtc ccttggatgc accagttgat ggagtagaag atgccaagcg
    36721 ggttgccgct gaagcggcag acttggtcga attcattcgt caaatgccat ttgtagtaga
    36781 gacagacaag tatatctttg ttcacgcagg tattgatttg accttggatg actggcatga
    36841 aacaacagat tataaaaaag tatggcttag aaaaccattc cacggagctg aaaatcatac
    36901 tggaaaaacc attgtcttcg gtcatacacc ggtctatggt ttgttacagc aagaacgcgg
    36961 tacatctgag ctttggacta cagaagatgg caagattgga atggatggag gagctgttta
    37021 tggtggtgtc cttcacggga ttgtctttac agaccaagga atgacagaac accactttat
    37081 cgaaaatgac ggctttgtcg ctgaagatta gtactcctag cagggtatgg tcttgtcaaa
    37141 atatcaaaaa caatttataa taaatagata ccctgaaagg aagagaatca tgaacttaga
    37201 agaattgaaa aaacgacagg agaagatccg taacttctct attatcgccc atattgacca
    37261 tggaaaatca actctagcag accgcatttt ggaaaaaaca gagacggttt caagtcgtga
    37321 aatgcaggcc cagcttttgg atagcatgga gctagagcgg gaacgtggaa ttactattaa
    37381 gttgaatgcc atcgagttga attacactgc aaaagatggg gaaacttata ttttccattt
    37441 gattgacaca ccagggcacg ttgactttac ctatgaagtt tcacgttcgc tagctgcctg
    37501 tgagggtgct attttggtgg tcgatgcggc tcaaggaatt gaggctcaaa ctcttgccaa
    37561 cgtttatctg gctttggata atgatttgga aatcatgcct atcattaata aaattgacct
    37621 gccggctgca gatccggagc gcgtgcgtac agagattgaa gatgtgattg gtttggatgc
    37681 cagtgaagca gttttggctt ctgccaaggc tggtattggg attgaagaaa tcctcgagca
    37741 aattgtagaa aaagtaccag caccaacggg tgatgtgacg gcgccactta aggccttgat
    37801 tttcgactct gtttacgatg cttaccgtgg ggttatcctc caagtgcgtg tcatggacgg
    37861 agtggtcaaa cctggtgata agattcagct catgagcaat agtaagacct ttgatgtggc
    37921 cgaagtcggt atttttacac caaaagcggt tggtcgtgat ttccttgcga ctggtgatgt
    37981 tggttacatt gcggcgtcta tcaagacggt tcaggatact cgtgtgggtg ataccgttac
    38041 cttggcaacc aatcctgcgg cagaaccatt acatggttat aagcagatga atcctatggt
    38101 ctttgcgggt ctctacccaa tcgaatcaaa caaatacaat gacctgcgtg aagcgcttga
    38161 aaaattgcaa ctgaatgatg ctagtcttca gtttgaacca gaaacatctc aggcacttgg
    38221 atttggtttc cgttgtggat ttcttggact tctccatatg gatgttatcc aggaacgttt
    38281 agagcgtgag ttcaatattg acctcatcat gacagctccg tctgttattt acaaagttaa
    38341 tttgaccgac ggtgagtcta tggatgtgtc taacccatct gagtttccag acccaactaa
    38401 gattgcgacc attgaagagc cttatgtcaa ggcgcaaatc atggtaccac aggagttcgt
    38461 cggagcagta atggagctag ctcagcgtaa gcgtggggac tttgtgacta tggactatat
    38521 tgatgataac cgtgtcaatg ttatctatca aattcctctt gctgaaattg tctttgactt
    38581 ctttgataaa cttaagtctt cgacacgtgg ttatgcaagc tttgactacg aattgtcaga
    38641 atatcgccca tctaagctgg tgaaaatgga tatccttctc aatggagata aggtggatgc
    38701 cctcagcttt atcgttcaca aggactttgc ctacgaacgt gggaaactca tcgttgataa
    38761 actcaagaaa atcatccctc gccaacaatt tgaagttcca atccaagcgg ctattggaca
    38821 caagattgtc gctcgtactg atatcaaggc ccttcgtaag aacgtacttg ctaaatgtta
    38881 tggtggtgac gtttctcgta agcgtaaact ccttgaaaaa caaaaagctg gtaagaaacg
    38941 catgaaatcc atcggatcag ttgaagttcc gcaagaagcc ttcctcagcg tcttgagtat
    39001 ggatgaagaa taagttatca gaaatgcctt tccttgttca caggaaattt atataagaat
    39061 caatagtaaa gcaggcttag atggtctgct tttttagttt ttatactctt cgaaaatctc
    39121 ttcaaaccac gtcagcgtcg ccttactgta tgtatggtta ctgacttcgt cagtcttatc
    39181 tacaacctca aaactgtgtt ttgagcaacc tgcggctagc ttcctagctt actctttgat
    39241 tttcattgag tattagaaca gaaaaaatgc ttggagtatt tgtttgtgtg tttattttta
    39301 tataacaaac tataaacaaa acaaaaatat aaaaaaagag acaaaaaaga acagaaagta
    39361 attgacaacg gtttcatata gtgttatact tatggcataa agttaatgga aagaagggaa
    39421 aaacttatgg tattagatta tttctttgac aaaaaccttg tgttttgctt agaagcggat
    39481 aatcaagaac aactctttga tcaggttgca actttattgg aagaacgaga aattgtcact
    39541 ccaacttatc gtgaagcttt gatcacgcgt gaaaagtcat ttccaactgg tttagatatg
    39601 gaatttctag gaaaggactt gccaaatgta gcgattcctc atacagatat tgttcataat
    39661 ctagctgaga aagtggtggt tgttcgatta gaaaaaccag taacttttca caatatgata
    39721 gctcctgata aggaagtaga agtatccttg ctcttcttta tcatcaataa ctcaagttca
    39781 agtcaaacaa atattctggc tcagttgatg gactttttca caggaaatgg acatcttgaa
    39841 gacctatcaa aaatttc
//
LOCUS       DAVEHY010000018        39243 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVEHY010000018 DAVEHY010000000
VERSION     DAVEHY010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.018"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            2734..4116
                     /locus_tag="VUZ44_001159"
                     /pseudo
     CDS             2734..4116
                     /locus_tag="VUZ44_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            4097..4300
                     /locus_tag="VUZ44_001160"
     CDS             4097..4300
                     /locus_tag="VUZ44_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320077.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            4303..4653
                     /locus_tag="VUZ44_001161"
     CDS             4303..4653
                     /locus_tag="VUZ44_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320078.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            4663..5079
                     /locus_tag="VUZ44_001162"
     CDS             4663..5079
                     /locus_tag="VUZ44_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEU0320079.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            5083..5415
                     /locus_tag="VUZ44_001163"
     CDS             5083..5415
                     /locus_tag="VUZ44_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU0320080.1"
                     /translation="MQQITEIITNGAISILVVLAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVASETGFKGDEKLEQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            5419..6375
                     /locus_tag="VUZ44_001164"
     CDS             5419..6375
                     /locus_tag="VUZ44_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU0320081.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(6513..6692)
                     /locus_tag="VUZ44_001165"
     CDS             complement(6513..6692)
                     /locus_tag="VUZ44_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320082.1"
                     /translation="MRKVIEELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(6834..6983)
                     /locus_tag="VUZ44_001166"
     CDS             complement(6834..6983)
                     /locus_tag="VUZ44_001166"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320083.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            complement(7584..7676)
                     /locus_tag="VUZ44_001167"
     CDS             complement(7584..7676)
                     /locus_tag="VUZ44_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU0320084.1"
                     /translation="MMDTILKTIIGPIVVGVVLRLVDKWLNKDK"
     gene            7837..8808
                     /gene="ruvB"
                     /locus_tag="VUZ44_001168"
     CDS             7837..8808
                     /gene="ruvB"
                     /locus_tag="VUZ44_001168"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU0320085.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGIPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            8897..9361
                     /locus_tag="VUZ44_001169"
     CDS             8897..9361
                     /locus_tag="VUZ44_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU0320086.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQFYMHQHSPHTAFYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            9592..10350
                     /locus_tag="VUZ44_001170"
     CDS             9592..10350
                     /locus_tag="VUZ44_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU0320087.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            10359..11162
                     /locus_tag="VUZ44_001171"
     CDS             10359..11162
                     /locus_tag="VUZ44_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU0320088.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            11184..12443
                     /gene="rseP"
                     /locus_tag="VUZ44_001172"
     CDS             11184..12443
                     /gene="rseP"
                     /locus_tag="VUZ44_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU0320089.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            12456..14309
                     /locus_tag="VUZ44_001173"
     CDS             12456..14309
                     /locus_tag="VUZ44_001173"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU0320090.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVAQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            14408..15787
                     /gene="bglA"
                     /locus_tag="VUZ44_001174"
     CDS             14408..15787
                     /gene="bglA"
                     /locus_tag="VUZ44_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU0320091.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            15980..17788
                     /gene="glmS"
                     /locus_tag="VUZ44_001175"
     CDS             15980..17788
                     /gene="glmS"
                     /locus_tag="VUZ44_001175"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU0320092.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVAPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(17865..18002)
                     /locus_tag="VUZ44_001176"
     CDS             complement(17865..18002)
                     /locus_tag="VUZ44_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320093.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEISNHTYGKATLTWFEEI
                     F"
     gene            18059..19108
                     /locus_tag="VUZ44_001177"
     CDS             18059..19108
                     /locus_tag="VUZ44_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU0320094.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(19208..23071)
                     /gene="spuA"
                     /locus_tag="VUZ44_001178"
     CDS             complement(19208..23071)
                     /gene="spuA"
                     /locus_tag="VUZ44_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU0320095.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPATEPP
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDEAIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDE
                     TYSYDGKLGADLREEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVYTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYRTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENK
                     PSQATADSQAEQPAQEAQASSVKEAVRKESVENSSKENISATPDRQAELPNTGIKNEN
                     KLLFAGISLLALLGLGFLLKNKKEN"
     gene            23488..23901
                     /gene="rpsL"
                     /locus_tag="VUZ44_001179"
     CDS             23488..23901
                     /gene="rpsL"
                     /locus_tag="VUZ44_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU0320096.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            23921..24391
                     /gene="rpsG"
                     /locus_tag="VUZ44_001180"
     CDS             23921..24391
                     /gene="rpsG"
                     /locus_tag="VUZ44_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU0320097.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            24816..26897
                     /gene="fusA"
                     /locus_tag="VUZ44_001181"
     CDS             24816..26897
                     /gene="fusA"
                     /locus_tag="VUZ44_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU0320098.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            27001..31392
                     /locus_tag="VUZ44_001182"
     CDS             27001..31392
                     /locus_tag="VUZ44_001182"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU0320099.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPVEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEAIYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            31494..31757
                     /locus_tag="VUZ44_001183"
     CDS             31494..31757
                     /locus_tag="VUZ44_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU0320100.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            31750..32028
                     /locus_tag="VUZ44_001184"
     CDS             31750..32028
                     /locus_tag="VUZ44_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU0320101.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECYTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            32049..32201
                     /locus_tag="VUZ44_001185"
     CDS             32049..32201
                     /locus_tag="VUZ44_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320102.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            32223..33464
                     /locus_tag="VUZ44_001186"
     CDS             32223..33464
                     /locus_tag="VUZ44_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU0320103.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIIDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVGGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAS"
     gene            33474..33704
                     /locus_tag="VUZ44_001187"
     CDS             33474..33704
                     /locus_tag="VUZ44_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU0320104.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            33725..33802
                     /locus_tag="VUZ44_001188"
                     /pseudo
     CDS             33725..33802
                     /locus_tag="VUZ44_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            33972..34694
                     /locus_tag="VUZ44_001189"
     CDS             33972..34694
                     /locus_tag="VUZ44_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU0320105.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGILLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            34911..36245
                     /gene="pepC"
                     /locus_tag="VUZ44_001190"
     CDS             34911..36245
                     /gene="pepC"
                     /locus_tag="VUZ44_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU0320106.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(36301..37212)
                     /locus_tag="VUZ44_001191"
     CDS             complement(36301..37212)
                     /locus_tag="VUZ44_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU0320107.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(37236..38039)
                     /locus_tag="VUZ44_001192"
     CDS             complement(37236..38039)
                     /locus_tag="VUZ44_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU0320108.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(38067..39056)
                     /gene="manX"
                     /locus_tag="VUZ44_001193"
     CDS             complement(38067..39056)
                     /gene="manX"
                     /locus_tag="VUZ44_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU0320109.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYTKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT        11428 a         7512 c         9135 g        11168 t
ORIGIN      
        1 gctggtgtga atcgtctgac tgaaggcctt agaaccaaag tggatatcag cgcactcaac
       61 gtgactgctg aaaatatccg gcaatctgtg aagagtcttg agacagacac gcagaacaag
      121 ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ccggctctat ccgtcaggaa
      181 atcctgaacg caaccaagga taaagccagc aagtcagaac ttacgcagac agctgaggag
      241 ctctctagta agatagcgag tgtgcaggtc ggaggaatca acctcttgcg taatactgcg
      301 agtttgttga ttggcgatcg ttcaaaagga tgttggatga gtgcaagcgg aggaaatggg
      361 cgagcgatta gcgtagaagt tttggatcct cccaaaaaaa tgataaaaaa catgattcgt
      421 gttattgaaa atacgaatgg tggaaataaa gatttaactc aacttgttag attgcgaatt
      481 ggtgaaaagt acacgatttc ttgttatgca aggattgcta gcgatagccc aaatgcaaac
      541 gtgaacttgc tatttcgttc gtgggcaaat aataccgatt taaatcgcaa atttcagaaa
      601 tccatctctc ataaaaattg gcaaaaatat tcatttacat ttactgctga tgcaattgaa
      661 aattcaattc aatttggaca atctggcgca ggaattatcg aaatatgcgc tccgaaaatc
      721 gaatcaggaa cgttagcgac tgattacagc gaagctcctg aagatataga aggtcagatt
      781 tcaacagttg aatccaactt taaacagcgt gctgattcac tcgaagctgg tgtaagccgt
      841 ctgactgaag gccttagaac taaagtggat atcagcgcac tcaacgtgac tgctgaaaat
      901 atccggcaat ctgtgaagag tcttgagaca gacacgcaga acaaactaaa tcagaagttg
      961 agtcaggctg aatttgaggt gcgagctggc tctatccgtc aggaaatcct gaacgcaacc
     1021 aaggataaag cagataagac tttagttgta tctgaagctg ggaaattgcg tgaagaattt
     1081 tcaaaaatga aggtgggagg acggaatcta tggataaaat ccaagacggt tggagctgta
     1141 attgaaaaat tacctgaaaa ccacgtcaca ggtcaaaaag aatgctatag gctagagaac
     1201 aactctactt taacgttcaa cattgaacca gatttcagct caaggttgta tcaaaaagtt
     1261 acttttagcg cttgggtcaa gtacgaaaat gtagtccaag gtcgaaattt ttggaatgta
     1321 tttaattgct tcaaacatta tctttttaga aaaaatagtg agaccggagt acagagtggt
     1381 ccagattatg ctacgcttgg tatgtataaa ggttcggcag attggaaata tattacattc
     1441 acttatgact actctgaaaa aacaaatttt gatcaattga agacatcatt gcgattcaat
     1501 cttgaaggtg ctacaagcgg tacagcttgg gtaacaggaa tcaaggttga aatcggtagt
     1561 gtggcgacgg actggagtcc tgcgcctgag gacgctgatg gtctcatcac tgaagctaag
     1621 gctacctttg agcggacagc tcagggcttg cgaaccgatt tatcagctat tcaggaatat
     1681 gtaaataaag acggtcagcg acaggaagcc ctacagcgct atactcgtga ggagagcacg
     1741 agacaagcga cagcagtccg tgagctggtc aatcgtgatt tcgttggtaa ggctacttat
     1801 caagaagatg ttaagggtat caatcagagg attgaagctg ttaaaactag tgcgaataaa
     1861 gacatcgcta gtcaaatcgc tagctatcgt caatctgtag atggtaagtt cacggatatt
     1921 tcaagtcaga taactactta taagcaagat gtgggcggtc aaatcagtgg tctatcaaat
     1981 agacttacaa gcagtgagca aggaaccact actcagattt caaatatttc aaatcggata
     2041 aacagtaata agcaaggcac agataatcag atttcaaatt taaagactca ggtcgctaca
     2101 aacaaggata atgctgaacg acaaatgggt agaatatctg atcaggtttc tgcaaacaaa
     2161 gcgaatgctg atcgtcaatt tgcgaatgtg accaatcaat tagtgcgaaa agtagagact
     2221 actgacttcc agcgtgttaa ggaaaccagt aaactttacg agcggatttt gggcaatact
     2281 gaaaatggaa ttgcggataa ggttgctcgc atggctctga ccaatcaact gtttcaggtt
     2341 gaggttggga aatatagtgt aagcggccct aacctcatta agaatagtga ttttaaaaat
     2401 ggtacgaatg aatggggctc aactcaaaat ttaggaagat tggttaagca tagcttttat
     2461 cacaacgggc agaaagacct tatgcgttta agtaatgcaa ctaaaaacga aaactttttg
     2521 tatagtcacc gttttaatct tgaacgaaat actgactatg tactgaattt tagaggattt
     2581 aacaacagtg ctctagcaag ctatgatgtt tatattttgg gacgaagagc aggcgagagc
     2641 gatggattca caatcgttaa gaaagttgtt agcagcaaga aactatctac ctctagatgc
     2701 gaagatgtct cagtaacttt taattccgga gaaatggata atgcttacat tcgttttgat
     2761 aacaatggtt catcatcagg aacagctgat ttgtatatta cagaagttga cttgtacaaa
     2821 ggttataaac ctagaacatg gcaaccacat acagaagatg cagtcgcaga tgcgaataag
     2881 aagcttgaag caacgcaaac aaaaatgact caactagctg gctcatgggt agttgaaaac
     2941 atcaactcgg ctggagatat catctctgga atcaatcttg gcgccaatgg acataaccgc
     3001 tttgttggga aattgaccca catcactgga gagaccctga ttgacagagc agtcatcaag
     3061 tctgccatgg ttgataagct caaaacggcc aattttgaag ctggttcggt cacgactacg
     3121 atattagacg ctgaagcggt aactgctgag aagttgaaag ttgacgatgc gcttattaga
     3181 aaattaactg caactgatgc ttttattgac cgactgacat ctaaacgtat cttctctact
     3241 aaggttgagt ccgtcatttc tagctcaacc ttcctagaag cctatcaagg ccgaatcggt
     3301 ggattcacac ttggtcaatt tgaccagggt ggcggtcgct ggatttcagg tgtcaatcag
     3361 ttctctgttg gtatggggaa tggtgccggg tatggagtcc ggacagcctt ctgggcgaac
     3421 tggggaaata attggaacta tgccggacct aaagcatgga acgtcaatac tgatgggaaa
     3481 atgtactgta ggaatgaagt cggtttttat gatcaagtgg atttttcgaa ttcatcgaga
     3541 gcaaacttct atgggaatac tactttttct cgttctcctg tgttttcaaa tggtatcgaa
     3601 cttggaagta aagatgtgct tggtgatggt tggaatccca aaggcggaag gaatgcggtt
     3661 gtttggtgga atcaggtcgg tagcggtagc gtgaagtatt ggatggaaca aaaatcagac
     3721 agacgcttaa aagagaacat cacagataca gctgtgaaag ccttggataa aatcaacaga
     3781 ttaagaatgg ttgcatttga tttcatcgaa aataagaaac atgaggagat tggtctaata
     3841 gctcaagagg ctgaaaccat cgttccaaga attgtctcac gagatcctga gaatccagat
     3901 ggctatctgc atattgacta taccgcttta gttccttact taatcaaggc tattcaagaa
     3961 ttaaatcaaa aaatagaaaa aatggagaaa acaatagcat gaataacaac atgttgacca
     4021 atatcgcact ttaaagcaat tcaggagctt gctcttgaaa atagaaaacg aacacacaga
     4081 ttggagaact tagaaaatga acacagaaca gcttaaccaa gccttacaaa tgacaattag
     4141 tgaaatgtca acaacttcaa caaattcgat gattacaagt aatatcttga gtattcagtt
     4201 gaatgagcaa agggaagaga atcaaagact tcaagcacga gtggatgagc tggaagctct
     4261 gcttgatgaa caaactaaac cagcagacaa aggagaatag acatggcaga aacaattcaa
     4321 aacacagata acttactaga ccttacaaaa atcacagaac catttgatct tgcgagcgct
     4381 ttgcgctaca tgaaagaaaa tggagagttc attcgttgca agaatgtaag cgatgacttc
     4441 tatatgtatc gtgacgttca aaaacgtcct gtgatcgtaa atggccgtcg ccaattcaag
     4501 gatgttgaaa ccgtttgggc attcaaccag tggggtggta caatcgcaac aatcaacgta
     4561 gccgttctgt tgaatcatga attctatatc atgaaatttg atgcagaggg caatcctgac
     4621 tggacggatc caacggtaaa acctaaagaa taggaggtgt gtatgcaaat tgaatttttc
     4681 aattttctaa gaagtgtcgt acagactgaa gatggtttgg tcttgtacgc tctagcactg
     4741 attgtctcaa tggaaatcat tgattttgtg acagggacga ttgcggcgat tatcaatcct
     4801 gacatcgagt acaagagcaa aatcggcatt aacgggctcc ttcgtaagat ttcaggggtt
     4861 ctcttactga tgatcctcat tccggcgtcc gttttgttgc ctgaaaagac aggttttgta
     4921 ttcttgcact caatctatct cgggtacatc gcatttactt ttcaatctct cattgaaaat
     4981 taccgcaaat taaaaggaaa tgttactctt tttcagccga ttgtaaaagt atttcagcga
     5041 ttacttgaaa aagatgatga tacgaaaaaa ggagaataac aaatgcaaca aattactgaa
     5101 atcattacta atggagcaat cagcatccta gtcgttttgg caggggtggt agttagggca
     5161 gtcaaggact acctggttca aaaaggtgga gaaaagacca tcaaaatcgt tgaaatcttg
     5221 gccaaaaacg cagttaatgc cgtggagcag gttgcctcag agactggctt taaaggcgat
     5281 gaaaagctgg agcaggctcg tgctaaagtc cgtgctgagc ttacaaaata caatattagt
     5341 atgactgaca aagacttaga caccttcgta gagtcagcag tgaagcagat gaatgacgca
     5401 tggaaaggac gatagggaat ggatatcgat agaaacagac tacgtacagg cttgccccag
     5461 gttggggtgc agccttatcg acaagtacat gctcactcaa caggtaaccg caactcaacc
     5521 gtacagaatg aagcggatta tcactataga aaggaccctg aactagggtt cttttcacat
     5581 gttgtcggaa acggccgtgt catgcaagta ggtcctgtga acaacggaag ttgggatgtt
     5641 gggggcggtt ggaatactga gagttacgca gcggttgaac tgattgaaag ccattcaact
     5701 aaagaagagt tcatgacgga ctaccgcctc tatatcgaat tgctacgcaa tctagcggac
     5761 gaagcaggct tgccgaagac tcttgataca gacgacttgg caggtatcaa gacgcatgaa
     5821 tactgtacca ataaccaacc aaacaaccac tcagaccatg tggatccata tccatatctt
     5881 gcaagttggg gcattagccg tgaacagttt aagcaagaca tcgaaaacgg cttgagagct
     5941 gcaacaggct ggcagaaaaa tggcactggc tactggtacg tacactcaga cggctcttat
     6001 ccaaaagata agtttgagaa aatcaacggt acctggtatt atttcgatgg ctcaggctat
     6061 atgctttcag accgctggaa gaagcacaca gacggtaatt ggtactactt tgaccaatca
     6121 ggcgaaatgg ctacaggctg gaagaaaatc gctgagaagt ggtactattt tgatgtagaa
     6181 ggtgccatga agacaggctg ggtcaagtac aaggacactt ggtactactt agacgctaaa
     6241 gaaggcgcca tggtatcaaa tgcctttatc cagtcagcgg acggaacagg ctggtactac
     6301 ctcaaaccag acggaacact ggcagacaag ccagagttca cagtagagcc agatggcttg
     6361 attacagtta aataaataga aaggaaactt tctaaattgt tctttcaccg caggcttagg
     6421 cttgcggttt tttatttgct ctgattcttt aaaaaagcgt tttcttgaag aatagagagg
     6481 tgttttgtca aaaataaaaa cagtgaccga aatcactgct tatcagttgt agcaaattca
     6541 tagagctttt ctgccgttag aagagccatt ttgtccatgc ttgtttttcc ttttctgagg
     6601 tcagaaacag tagtccatgg aactccagca ccttgcgaaa tagcagatgt agacatcgaa
     6661 ctgtctaaca attcttcaat aactttcctc atcctatttg tcctttttat tttttagata
     6721 aatatataca ttgattgcaa ttataaaaat agctattgca ctaaccattg catttcctct
     6781 ttccatttga taaaatagag gtgtaagggg ctttcgcccc aacctcttag cgtttacctt
     6841 tttctttgac gggatttcgg tttacgcttt ttgttttgcc ttgcgaccgt tattgcggtc
     6901 actagacttg cgatagcagt taccgtttca ggaatattgt ctattgcctt ttcaagtaac
     6961 ctgagccaat cttctttgtt caacttcatc accccctttc cttatcttga ttatattata
     7021 tcacggtaca ccgagaaagt caagcgtttt gatgaagttt ttttaatttt ttcaaaaaaa
     7081 aaatagacct tgtccagagg tcggggagtt ggagggggca ccctccaaaa gcattgattt
     7141 aataaggttt tattttacct ttttcataat aatctccctt aactccaccg aatcaggtgg
     7201 agttttttag cgaatatgac taagaaatag gtctgtggtc gcttcagcta gttcaaactc
     7261 aatttgattg taagtgactg ttaattgaag gactggaact actgtaataa taattttgct
     7321 tgtctagtag tggcgtatta aatgagaagt gacatgtaag attgtctctt cgtttacgaa
     7381 atcaaaattt ctatgaaatt gatagaatcc ctaacgttct cttaatctta accgtcttgt
     7441 cgtacagcgg ttgaagaaaa tgtaaagttt tgacaaaatt cgtgaactat gggataataa
     7501 aagggaatta agtattgtgt ctatatcata ggctagaaaa gaccccaagc tcacgaccaa
     7561 ataagcttgg ggtctttttg acactatttg tccttgttta gccatttatc gactaagcga
     7621 agaacgacac cgaccacaat tggtccgatg atagttttaa gtattgtatc catcatgggc
     7681 tatctcacct cctttcgcag gcggtgtagc agtgtcgtag aatattatac cacataagtg
     7741 ctaaacttag gagtcaccca atcaggtggc ttttttgttt gtggcttggt tttttgatat
     7801 aatagagcca tgagtagaat tttagataat gagataatgg gggatgagga gttagtagaa
     7861 cgcacgctcc gtcctcagta tttacgtgaa tatatcggac aggataaggt caaggaccag
     7921 ctacaaatct ttattgaagc tgccaaaatg cgggatgaag cgctggatca tgtgctctta
     7981 tttgggcctc caggtctcgg gaaaacgacc atggcctttg ttattgccaa cgaactggga
     8041 gtcaatctta agcagacgtc gggtccagtc attgaaaaag ccggagatct ggtagctatt
     8101 ttgaatgagt tagagcctgg ggatgtactt tttattgatg agatccatcg tttgccaatg
     8161 tcagtggaag aggtgcttta tagtgctatg gaggacttct acatcgatat tatgattggg
     8221 gctggtgagg gtagtcgtag tgttcatttg gagttaccac cttttacctt gattggtgcg
     8281 acgactcggg ctggtatgct ctccaatccg ctacgggcac gttttgggat tacaggccat
     8341 atggagtatt atgcccatgc tgacttgaca gaaattgtcg agcggacggc agatattttt
     8401 gagatggaaa tcactcatga ggcagcatct gagttggccc tacgtagtcg tgggatccct
     8461 cgtattgcca atcgtctcct caagcgcgtg cgcgattttg cccagataat ggggaatggg
     8521 gtaattgatg atattattac cgataaggct ttgactatgc tggatgttga ccatgaaggt
     8581 ttggactatg tggatcaaaa aatccttcgt accatgattg agatgtacag tggaggacct
     8641 gttggtctag gaactctttc tgtgaatatc gccgaagagc gtgagacagt tgaagatatg
     8701 tatgagcctt acttgattca aaaaggtttt atcatgcgga cacggtctgg acgggtggcg
     8761 actgctaagg catatgagca cttaggttat gaatacagtg aaaaataagc aagaaatctt
     8821 agaggctttt agagaaaatc cagatatgat ggccattctg acgatcatcc gagaccttgg
     8881 tttgaaagac tcgtagttgg cagcaggttc tgtcagaaat ttcatctgga atcttttgtc
     8941 agacaaatcc ccttttgatc atgaaacaga tatagatgtg attttctttg atccagattt
     9001 ttcttatgag gaaaccttat tactggagaa aaagctgaga gaggattttc ctcagtacca
     9061 gtgggaattg aaaaatcagt tctatatgca tcagcacagt cctcacactg ctttctatac
     9121 cagttctcgt gatgctatga gtaagtatcc agaacggtgt acggcagttg gactgcgctt
     9181 gaatgaagaa tcagattttg aactctatgc accttatggt ttggaggata ttttgaattt
     9241 tcaagttcgt ccaactcctc atttcttaga aaatgaagac cgaatggaac tctatcaaac
     9301 acgtttatcc aagaaaaatt ggcaggagaa atggaaaaat ttgattttta aaaatactta
     9361 aggaaacttt aagctaggga gtgtacacta agttcataag ttaagaagac cttaacttaa
     9421 actcctaaaa ctttttcata ataatctccc tataaaaata aagtcgccca atcaggcggc
     9481 ttattttttt gaaaaatggg catggtgcct gagaataaat agcttagtga tagaagaaaa
     9541 tggggaaata tggtataatg aaacgataga tttttgaata ggaataagat catgtttgga
     9601 ttttttaaga aagataaggc tgtggaagta gaggttccga cacaggttcc tgctcatatc
     9661 ggcatcatca tggatggcaa tggccgttgg gctaaaaaac gtatgcaacc gcgagttttt
     9721 ggacataagg cgggcatgga agcattgcaa accgtgacca aggcagccaa caaactgggc
     9781 gtcaaggtta ttacggtcta tgctttttct acggaaaact ggacccgtcc agatcaggaa
     9841 gtcaagttta tcatgaactt gccagtagag ttttatgata attatgtccc ggaactacat
     9901 gcgaataatg ttaagattca aatgattggg gagacagacc gcctgcctaa gcaaaccttt
     9961 gaagctttaa ccaaggctga ggaattgact aagaacaaca caggattgat tcttaatttt
    10021 gctcttaact atggtggacg tgctgagatt acacaggcgc ttaagttgat ttcccaggat
    10081 gttttagatg ccaaaatcaa tccaggtgac atcacagagg aattgattgg caactatctc
    10141 tttacccagc atttgcctaa ggacttacga gacccagact tgattatccg tactagtgga
    10201 gaattgcgtt tgagcaattt ccttccatgg cagggagcct atagtgagct ttattttacg
    10261 gacaccttat ggcctgattt tgacgaagcg gccttgcagg aagctattct tgcctataat
    10321 cgtcgtcatc gccgatttgg aggagtttag gaggaaatat gacccaggat ttacagaaaa
    10381 gaaccttgtt tgcagggatt gccctggcta ttttcctacc aattttaatg attgggggcc
    10441 tcttgcttca gatagcaatc ggaatcatag ccatgctagc catgcatgaa cttttgaaga
    10501 tgagaggtct agagaccatg acgatggagg gcctcttgac cctctttgca acctttgcat
    10561 tgaccattcc cttggagaat tacctgactt ttttgccagt tgatgggaat gtggttgcct
    10621 atagtgtttt gatttcaatc atgttaggaa cgaccgtttt tagcaagtct tatacgattg
    10681 aggatgcggt tttccctctt gctatgagct tctacgtggg ctttggattt aatgctttac
    10741 tagatgctcg tgttgcaggt ttggacaagg ctctcttagc cttgtgtatc gtctgggcga
    10801 cagacagtgg tgcctatctt gttgggatga actatgggaa acgaaagtta gcaccaaggg
    10861 tatcgcctaa taaaaccctt gagggtgcct tgggtggtat tttaggagca attttagtaa
    10921 ccattatctt tatgatagtt gacagtacag ttgctcttcc atatggaatt tacaagatgt
    10981 cagtctttgc tattttcttt agcattgctg gacaatttgg tgatttacta gaaagttcga
    11041 tcaaacgtca ttttggtgtt aaggattctg ggaaatttat ccctggacat ggtggtgttt
    11101 tggatcgttt cgatagtatg ttgcttgtat ttccaatcat gcacttattt ggactctttt
    11161 aatcaaaaga cggaggaaac gctatgctcg gaattttaac ctttattctg gtttttggga
    11221 ttattgtagt ggtgcacgag ttcgggcact tctactttgc caagaaatca gggattttag
    11281 tacgtgaatt tgccatcggt atgggaccta aaatctttgc tcacattggc aaggatggaa
    11341 cggcctatac cattcgaatc ttgcctctgg gtggctatgt ccgcatggcc ggttggggtg
    11401 atgatacaac tgaaatcaag acaggaacgc ctgttagttt gacacttgct gatgatggta
    11461 aggttaaacg catcaatctc tcaggtaaaa aattggatca aacagccctc cctatgcagg
    11521 tgacccagtt tgattttgaa gacaagctct ttatcaaagg attggttctg gaagaagaaa
    11581 aaacatttgc agtggatcac gatgcaacgg ttgtggaagc agatggtact gaggttcgga
    11641 ttgcaccttt agatgttcaa tatcaaaatg cgactatctg gggcaaactg attaccaatt
    11701 ttgcaggtcc tatgaacaat tttatcttag gtgtcgttgt tttttgggtt ttaatcttta
    11761 tgcagggtgg tgtcagagat gttgatacca atcagttcca tatcatgccc caaggtgcct
    11821 tggccaaggt aggagtacca gaaacggcac aaattaccaa gattggctca catgaggtta
    11881 gcaactggga aagcttgatc caagctgtgg aaacagaaac caaagataag acggcaccga
    11941 ctttggatgt gactatttct gaaaagggga gtgacaaaca agtcactgtt acacccgaag
    12001 atagtcaagg tcgttacctt ctaggtgttc aaccgggggt taagtcagat tttctatcca
    12061 tgtttgtagg tggttttaca actgctgctg actcagctct ccgaattctc tcagctctga
    12121 aaaatctgat tttccaaccg gatttgaaca agttgggtgg acctgttgct atctttaagg
    12181 caagtagtga tgctgctaaa aatggaattg agaatatctt gtacttcttg gcaatgattt
    12241 ccatcaatat tgggattttt aatcttattc cgattccagc cttggatggt ggtaagattg
    12301 tgctcaatat cctagaagcc atccgccgca aaccattgaa acaagaaatt gaaacctatg
    12361 tcaccttggc cggagtggtc atcatggttg tcttgatgat tgctgtgact tggaatgaca
    12421 ttatgcgact cttttttaga taatcgagga atattatgaa acaaagtaaa atgcctatcc
    12481 caacgcttcg cgaaatgcca agcgatgctc aagttatcag ccatgctctt atgttgcgtg
    12541 ctggttatgt tcgccaagtt tcagcaggtg tttattctta tctaccactt gccaaccgtg
    12601 tgattgaaaa agctaaaaac atcatgcgcc aagaattcga aaagattggt gctgttgaga
    12661 tgttggctcc tgcccttctt agtgcagaat tgtggcgtga atcaggtcgt tacgaaacct
    12721 atggtgaaga cctttacaaa ctaaaaaacc gtgaaaaatc agactttatc ttaggtccaa
    12781 ctcatgaaga aacctttaca gctattgtcc gtgattctgt taaatcttac aagcaattgc
    12841 cactcaacct ttatcaaatt cagcccaagt atcgtgatga aaaacgccca cgtaatggac
    12901 ttcttcgtac acgtgagttt atcatgaagg atgcttatag tttccacgct aactatgata
    12961 gtttggatag tgtttatgat gagtacaaag cagcctatga gcgtattttc actcgtagtg
    13021 gtttagactt caaggctatt attggtgacg gtggagccat gggtggtaag gatagccaag
    13081 aatttatggc cattacatct gctcgtacag accttgaccg ctgggttgtc ttggacaagt
    13141 cagttgcctc atttgacgaa attcctgcag aagtgcaaga agaaatcaag gcagaattgc
    13201 tcaaatggat agtctctggt gaagatacca ttgcttactc aagtgagtct agctatgcag
    13261 ctaacttaga aatggcaaca aacgagtaca aaccaagcaa ccgtgttgtc gctgaagaag
    13321 aagttactcg tgttgcaacg ccagatgtta aatcaattga tgaagttgca gccttcctca
    13381 atgttccaga agaacaaacg attaaaaccc tcttctacat tgcagatggt gagcttgttg
    13441 cagcccttct agttggaaat gaccaactca acgaagtcaa gttgaaaaat cacttgggag
    13501 cagatttctt tgacgttgct agcgaagaag aagtggcgaa tgttgctcaa gcaggatttg
    13561 gttcacttgg accagttggt ttgccagaga atattaaaat tattgcagat cgtaaggtgc
    13621 aagatgttcg caatgcagtt gtcggtgcta acgaagatgg ctaccacttg actggtgtga
    13681 acccaggccg tgattttact gcagaatatg tggatatccg tgaagttcgt gagggtgaaa
    13741 tttccccaga tggacaaggt gtccttaact ttgcgcgtgg tattgagatc ggtcatattt
    13801 tcaaactcgg aactcgctat tcagcaagca tgggagcaga tgtcttggat gaaaatggtc
    13861 gtgctgtgcc aatcatcatg ggatgttacg gtatcggtgt cagccgtctt ctttcagcag
    13921 tgatggagca acacgctcgc ctctttgtta acaaaacgcc aaaaggtgaa taccgttacg
    13981 cttggggaat caatttccct aaagaattgg caccatttga tgtgcatttg attactgtta
    14041 atgtcaagga tgaagaagcg caagccttga cagaaaaact tgaagcaagc ttgatgggag
    14101 ctggttatga agtcttgaca gatgaccgta acgaacgtgt cggtgttaaa tttagcgata
    14161 gtgacttgat tggtcttcca atccgtatca ctgttggtaa aaaagcggcc gatggcattg
    14221 tagaagttaa gatcaaggca actggtgaca ccattgaggt tcatgcagat aatgtgcttg
    14281 aaacgcttga aatcctaagc aagaaataaa aactataatc agaagaaaaa caaggaaaaa
    14341 atgtaactag tttttacctt gttttttctg tataatggga gaaatgagta gataaagagg
    14401 taaatgtatg ctaagatttc caaaggattt tgtctgggga tcctctactt ctggaccgca
    14461 gacagaagga cgtgtagctg gtgacggtaa gggagacaat ctctgggatt actggttcca
    14521 agtggagcca aatcgttact ataatgggat tggttcagat aagacatcga ctttttatga
    14581 aaattgggag cgggatattg agcttttgtt agagactggt cacacagcct ttcggacttc
    14641 tattcagtgg tcacggattt ttccacaagg ctgtggaaaa gtcaaccctc aaggtgtgga
    14701 tttttatcgt aaggtctttg aggctattaa ggctaaagga attcgtctgt tagtcaatct
    14761 ctatcatttt gatttacctt ttgcccttca agaggatggt gatggttggg aaaataaggc
    14821 gacagtctca gcctatgaag actatgctcg tttttgtttt gagacttatg gagatttagt
    14881 ggatcaatgg attaccttta acgagcccat cgttcctgta gaatttggtt atttttatga
    14941 tgcccattat ccacataagg tggatgcaga ggcagctgtt aaggtagcct atcatacaca
    15001 attggccagc agccgggctg ttaaggcttg ccatgaactt ttgcctgatt ccaagattgg
    15061 gattgtcctc aacttgacac cggcttatcc acgtagccag catcctgctg atgtcaaggc
    15121 agctcgtatt gcggcccttt ttcaggccca atctttctta gatccatctg tcttggggac
    15181 ttatccacag gagttggtag aaatcttgca tgaacacggt cttttacctg atgctacaga
    15241 ggaagagttg gaactcattc gtgataatac ggtggacttc cttggtgtca actactatca
    15301 acctttgcgt gttatggctc ctcgatttgc taagcatcca gagagtccac tcttaccaga
    15361 acatttttac gagccttatg tgatgcctgg acgtaaaatc aattctcacc gtggttggga
    15421 gatttatgag caagggattt atgacatcgc ccaaaatatc aaggaaaatt atggcaatat
    15481 tgagtggatg ttgactgaga atggtatggg tgttgaaggg gaagaaaaat tccgtcaaga
    15541 tggaatgatt caagatgatt accgtattga ctttgtaaaa ggtcatcttc gtgaacttca
    15601 ccgtgccatt gaagatggtg ccaactgtaa gggctacttg atttggacct ttattgactg
    15661 ctggtcatgg ctcaacagct ataaaaatcg ctatggtttg gtcgaattag acttggaaac
    15721 gcaagaacgt cgtctgaaga aatcaggcca ctggttcaaa gaattaagcg ataataatgg
    15781 attttaaaaa ggactctgac tgattatccc aatcggtcag agtttttatg cttacaggag
    15841 cttaatttga actataccaa tttttactct tgacaagtga aagaaacaag tatatactgt
    15901 ttttgctgat tctataaaag atgaattaga ctataccaat tttaaggaga aagcacagct
    15961 tgcctgtgtc gtatatacta tgtgtggaat tgttggtgtt gttggaaaca caaatgcaac
    16021 tgatattttg attcaagggc ttgaaaagct tgaataccgt ggctatgatt ctgcgggaat
    16081 ttttgtccta gatggtgctg ataaccattt ggtgaaggcg gttggtcgta ttgcagaatt
    16141 gtctgccaag acagctggtg ttgagggaac aactggtatc ggacatactc gttgggctac
    16201 tcacggaaaa ccaactgagg acaatgctca cccacaccgc tctgagacag aacgttttgt
    16261 cttggtgcat aatggggtga ttgagaacta tcttgaaatc aaggaagaat accttgcagg
    16321 tcaccacttc aaggggcaga cagatactga aatagccgtt catttgattg gaaaatttgc
    16381 ggaagaagaa gggctctcag ttcttgaagc ctttaaaaaa gctcttcata ttatccgtgg
    16441 ttcatatgcc tttgccttga ttgactctga aaatccagat gtcatctatg tagcgaaaaa
    16501 caaatctcca cttttgattg gtcttgggga aggctacaat atggtctgct cagatgctat
    16561 ggctatgatt cgtgaaacca accaatacat ggaaattcat gaccaagagt tggtaatcgt
    16621 caaggctgat agcgtggaag ttcaagacta tgatggtaac agtcgtgaac gtgctagcta
    16681 tactgcggaa cttgacttgt cagatatcgg taagggaact tatccttact acatgcttaa
    16741 ggaaattgat gagcaaccaa ctgttatgcg taaactcatt caagcctaca cggatgatgc
    16801 tggtcaagta gtggttgctc ctgctatcat taaggctgtt caagacgcag accgcatcta
    16861 catccttgca gctggaacat cttaccatgc aggatttgct tctaagaaaa tgttggaaga
    16921 attgacagat acaccagttg aacttggaat ctcatctgag tggggctacg gtatgccact
    16981 tctcagcaag aaaccactct tcatctttat cagccaatct ggtgaaacag cggatagtcg
    17041 tcaagttttg gtcaaggcta atgaaatggg aattccaagc ttaacagtga caaatgttcc
    17101 aggttcaacc ctctcacgtg aagccaacta taccatgctc cttcacgcag gacctgaaat
    17161 tgccgtggca tcaactaaag cctatacagc gcaaatcgca gcccttgcct tccttgcaaa
    17221 agcagtcgga gaagcaaatg gtaatgctaa agcgcaagcc tttgacctgg ttcatgaatt
    17281 gtcaatcgta gctcagtcta ttgaatcaac tctttcagag aaagaaacca ttgaagccaa
    17341 ggttcgtgaa cttcttgaaa caactcgtaa cgccttttac atcggacgtg gtcaagatta
    17401 ctacgtagcc atggaagcaa gtctcaaact caaagagatt tcttatatcc agtgtgaagg
    17461 ttttgcggca ggagaactca agcacggaac cattgccttg attgaagaag gaacgcctgt
    17521 tttggctctc ttgtcagatc cagttcttgc caaccatact cgtggaaata tccaagaggt
    17581 cgcagcccgt ggtgccaaag tcctcactat cgcagaagag aatgtagcca aagataccga
    17641 cgatatcgtc cttacgaccg tacatccata cctctcacca atttcaatgg tcgtaccaac
    17701 gcaattagtc gcttactttg caaccctcca ccgtggcctc gatgtggaca aaccacgtaa
    17761 ccttgccaag tcagtaacgg tagaataagc taaaaaagtc tagttatcta ggctttttct
    17821 tgtgagcaaa ttggttgctt gtactcaaga ttcgtgttat actcttagaa aatctcttca
    17881 aaccacgtca acgtcgcctt gccgtaggta tggttactga tttcgtcagt tctatccaca
    17941 acctcaaaac actgttttga gcaacctgcg gctagcttcc tagtttgctc tttgattttc
    18001 attgagtatt agaataattt ttcaaattga agtacagaga tagacaagga gaatcacaat
    18061 ggtagaattg ggaatttcaa catttgggga aataacggag cttgaaggga ctggacaaac
    18121 ttacagtcat gctgaacgca ttcgccagtt ggtggcagag attgagctgg ctgacaaggt
    18181 tggtttggac gtatatggga ttggcgagca ccatcgggcg gattttgcag tatcagcccc
    18241 agagattgtc ctggccgctg gggcagtcaa taccaagaaa atccgtttga ccagcgcagt
    18301 cagcattctg tcaagcatgg acccgattcg tttgttccaa cagtatgcca ctatcgatgc
    18361 tttgtcaaat ggacgatcgg agattatggc tggaaggggc tctttcacgg aatctttccc
    18421 tctgtttggt tatgacttga aagactacga ctctcttttt gatgagaaat tagacttgct
    18481 tcagttagtc aatgaaaaga ccaagttaga ctggcaaggt cgattgactc aaacgattgc
    18541 tggtaaagaa gtttatcctc gtccagttca ggacaaattg cccttgtgga tagctacagg
    18601 tggtcatgtc gaatcaacag tgaagattgc tcaggctggt ctaccgattg tatatgctat
    18661 tattggtggt aatccacgtt attttaaaaa gttgattcag gcttatcgtg agattggaag
    18721 cgaagcgggc catgctgaca aagacttgaa agtgggagcc cattcttggg ggtggattgc
    18781 ggaagatggt gagcaggcgg tgaaagatta tttccatccg actaagcaag tggtggatgc
    18841 tatttccaaa gaccgtccgc actggcagga attgcgttat gagcaatatt tggagcaggt
    18901 agggtcaaat ggcgccatgt ttgttggcaa tccagatcag gtggccgaaa aattgattcg
    18961 catgatagag gatttaggat tggaccgctt catgcttcat ctaccgcttg gttctatgcc
    19021 tcatgaccag gttctgagag ctattgaact cttcggaaca caagttgcac ccaaagtacg
    19081 agcttatttt gctatgaaag aggcttaata aaaaatccta atcaagttta ttaggacaac
    19141 aaatattgta cgaaaattaa tcccccgagc tataatgctt gggggatttt tctataggag
    19201 ggctagctta gttctctttt ttatttttta gtaagaaacc gagaccaagg agcgcaagga
    19261 ggctgattcc tgcaaatagg agtttgtttt cgtttttgat tcctgtattt ggaagttcag
    19321 cttgtctatc tggggttgca gatatatttt ccttgctaga gttttctacc gattcttttc
    19381 gaaccgcttc ttttacagat gatgcttgtg cttcttgtgc tggttgttca gcttgtgaat
    19441 cagctgtagc ttggctaggt ttattttccg catcagctac tttggcatct ggtttagtag
    19501 aatcaggtct agcttctgga gctgggtctt gatgtgcagg gtgagaagct tcattttgat
    19561 gttcaggctt ggaaggggtt gagtctggtt tctcttctgc agttgactca tggctagttc
    19621 cattttgaga gactcgaaga acagtagctg taagggcatt caatttcaag cctttttcag
    19681 tccattcaag tcctttcggg ttggcaattc cgactgatcc tgcttggttt tcatctgcca
    19741 aaacttccgc atttcttaga tgtgcaaagg cagttcccaa attaaattcg cgagcttttt
    19801 catccgcatt gacaaagact gcgtagatat cgccgtttgg agcagtgatt tgatagccaa
    19861 tcactacatc ctctttttcc acaccatttt ggcctgggac agtgatgagg tggacacggt
    19921 ctttgatatc ttgaagactc ttaagtcgga aggcatctgt agattgacga agggcaatca
    19981 aacctttcat atagtcacgg ctcttgacat tttcaggata agctttacca tctgtagcct
    20041 tagtccagtc aaacttgttg actgcatcac tagaatcgta agagtcatgg atgaagtaag
    20101 gatagtcaaa tgggttgccg tccttatcac gcaacaagtg agatttgttt ggaaccttat
    20161 cctctgctac aggagttctg taggctgggt cacggaattg tttggtacgt ccatattcct
    20221 ggccagagtg gataaacgga gttccttgag ctgtcaagac catgagattt ccaagtctca
    20281 aacgacggtg gatttcagca tagttctcag ccttgcttgg gtcttttttg atagactggg
    20341 caatgatgtc aaagagggtc aagttatcgt gggctgcgat gtattggatg acatctccag
    20401 ggctgtcagc ttcaaagtta gttggctgag caatgagatt tttaaagatg gtgttgacat
    20461 cacgcttgcc acctgtgata aaggcaggtt gaccttcgtt tggataacca gatttgaggt
    20521 tgttacggat gtcatctgaa aagacagcga cagtatcggt atgtttcatc caatcttggt
    20581 cagcagcttt agtaggcatg ttttcatcac cggcataggt tctccaacct tcaccaagca
    20641 tgatgaggtt tggattgagg gcgcgtgcag ccttgtaagc ttcttcgata gaagcggcgt
    20701 catggtctcc catcatatcg aaacggaatc catccacttt gtaggtataa actaggtatt
    20761 tgatagagtc aactaggagc cgtttggtca tatggtgggt tgttcccaag cgtccaccac
    20821 caaagctagt tcgaggtgtg ccatcggcat ccataaagtg gtagtagttt ggctctaggt
    20881 cttcaaagat atcgactttg gctgtgtggt tataaacgac atctaggata gctcccatac
    20941 cacgtttgtg gatttcgttg atgaggtttt taaattctgc gattcgtttt tctggattct
    21001 taggatcgct tgagtacata ccagtcaagg agaagtagtt ttgagggtca tatccccagt
    21061 tgtagttgct gttgcttgaa gcgtagtcag acaagcgttc atggtttttc aattcattga
    21121 caaagtagta agacaagact ggaaggagct ggatatgggt tacacccaag tctttgagat
    21181 agtctagttt ttcaatgaag gcttcaaaag tcccaaatgg tttggtcaag tcttttgcaa
    21241 tggcaggatc tgaagtgaag tcacgcacat gagcttcgta gataacggcg tcttcacgag
    21301 tcttgaaatt gtgaatctta ccataagtca agtcttgagg tccgagttta gctggatcta
    21361 caaaggcggc tttagccact ttatgggcat cgtcaatttt ggcatcgtcg ctattccaag
    21421 cagcaagaga tttagcgtaa ggatcgagtg caagaacagt tttaccttga cgctcgattt
    21481 ggtattgata atagtagcca gtgaaatctg tgattccgag tttgtttgtg ctgtctagag
    21541 tttgtttcca agttcctctt tccccttttt cgagagcgac agttccaact actttgtcag
    21601 ggtcattctt gtcgtagaca acaacagaaa ccttatcagc acttggtgac caaagggtca
    21661 aatcaacttg ttttccttct tctcttaggt cagctcccag tttgccatca tagctgtatg
    21721 tctcatcttt caggcgccag cttgttttgg tagtgaattg atcggaattg tagctaacag
    21781 tataaggatg ttttgtgtca gagaaatctc cgctgtaggt cactttctta ccagcttcat
    21841 cgattgcaac atcggtaata gttaccttgt ttcctaggtg attagtgatg ttggagtgtt
    21901 tgaggatatc ttctttttta gcaccgacaa gtgttgaaaa gctactttca atgctagaag
    21961 tgcctacgtg ttgggctcct gtcatacgga tatcatggac atagtatgga tttgtgtaaa
    22021 tcgcttcatc atcgtctttt aggaaaattt ggctatgatt tttcaaatct gtgaacttat
    22081 aattttcttt acggattttc acgtcgtctc cttgtttgct ctcatctagt aataaaaatc
    22141 caaattctct tgcggcttca ttaagaggaa tgtcgatata gcggccatat ttgcctgtag
    22201 ccgtaaagtc tgttccgtca ggccattgag cgctacttgg atttttcaca tctccccaat
    22261 accagagaga tttcttgtca tagttgccat ctgtgcggta gtagttgacg cgaacagttc
    22321 ctgcaggctg tggctcgtaa gagaaaacct tgtaatcttg gtctaaccaa gcctcgttca
    22381 tttttggaac tagtttttct acagatttat cgccggttag attttttcca gctgtattgt
    22441 tgatgaggaa gctaattttc ttggcttgtt ctccctttaa tttgacatct aggtaatagc
    22501 cgtagtcatc tttcttggca tccttgaagg acaaagctcc gtttggccag ttttcagatg
    22561 gtttttcaac atcgtcccaa gtccatagtc cttgagcatc cttgttttct tcaggaagtt
    22621 ttttgacatg gatacggaag tagttatctt cgatgggctc ttctgcctta gtttcagttg
    22681 ttactggact agtagaagta gttggctcac ttgaacgatc ttgtccagtt tgtggtgctg
    22741 gatcggctgg gcttgcagca ggagttggtg gctctgttgc aggtttttct tctgttttct
    22801 ctagggaagc gtttgcattt ccaggtgaag aaatatcact ttcattctta ccagagccag
    22861 ctgctgtatc agtaagaggt tgggcaaggg tggttgtatt tctgttgttg ggttcgttag
    22921 tggttggtgt actttcgtcg gatgagatag ttggtgtagc catggcaagc aagacaaggc
    22981 ttgcgccgat aaggacagaa ccagttccat ttttgaggga acggatgctg tagaccattt
    23041 ttttctcagt gtgagatggt gtttttctca taatgattct ccaatcaata aatttctata
    23101 tcagtatagc atgtagtaaa acaatatgca agcgttttct ttggtttgtg aaaaaaattc
    23161 ttacttttga gaagttttct gtactatttt atgtatcagt ataaatgacg gagataaaaa
    23221 tgtcacataa gccaagccgt attattagga agatgatgtg ttcccagcta tttttattca
    23281 gaaattgatc tctaacatta ccaataaaaa agaaaaatat cttgacaagc aagggaaaat
    23341 tttgttacaa taatagacgg tactttttac ttttggtctc tcaagagtgt acagggacgt
    23401 gctgacaaat gttgcaaaag tacacacaga tgatatctgt caccaagtgt atcatcacca
    23461 aaaataaaaa aacacaggag aatgtagatg cctacaatta accaattggt tcgcaaaccg
    23521 cgtaaatcaa aagtagaaaa atctaaatca ccagctttga acgttggtta caatagtcat
    23581 aaaaaagttc aaacaaacgt ttcttcacca caaaaacgtg gtgttgcaac tcgtgttgga
    23641 acaatgacac ctaaaaaacc taactcagcc cttcgtaaat tcgctcgtgt acgtttgagc
    23701 aaccttatcg aagttactgc ctacatccca ggtatcggac acaacttgca agagcacagc
    23761 gtggtgcttc ttcgcggtgg acgtgtaaaa gaccttccag gggtacgtta ccatatcgtc
    23821 cgtggtgcac ttgatactgc aggtgttaac gatcgtaaac aaggccgttc taaatacggt
    23881 actaaacgtc caaaagcata aggaaagggg ataaagagaa atgagtcgta aaaatagagc
    23941 tccaaaacgt gacgtattgc cagatccgct atacaattca caactagtta ctcgtcttat
    24001 caaccgcgtt atgcttgatg gtaaacgtgg tactgctgct tcaatcgttt acggtgcttt
    24061 tgagcaaatc aaagaagcta ctggcaacga tgcacttgaa gtatttgaaa cagctatgga
    24121 aaacatcatg cctgtacttg aagtacgtgc acgtcgtgtt ggtggttcta actaccaagt
    24181 cccagttgaa gttcgtccag aacgtcgtac aacacttgga cttcgttggt tggtaacaat
    24241 cgctcgtctt cgtggtgaac acacaatgca agaccgtctt gcaaaagaaa tcttggatgc
    24301 tgctaacaac actggtgcag ctgttaagaa acgtgaagat actcaccgta tggctgaagc
    24361 taaccgtgca ttcgcacact tccgttggta agataggatg cgaaagcgtt aagaaagtcc
    24421 cagagaaaat agggaatcga agcaggttgc ggttgcaacc aatgagattc atctttttct
    24481 ccagactttt agcttgagct caactaaatc atgatgctag gcacggtaag gatgcaaggt
    24541 gaaaatagga aactgacgca gtattcaacg aatacaagga gttttatctt tttcacgcag
    24601 catcccgttc cagctcacat cggctaacta actttagccc gggttcaaat tagctaaatc
    24661 gattagtatt agctataact cagcttacca tctcgtaagt tgaaaccaac aatagcatga
    24721 aaacattgag aacgggtagg tcctgcctat ccgtttttat taaaatcgtg ttataataga
    24781 atagaaatca aaaataaata ggagaaacaa acctcatggc acgcgaattt tcacttgaaa
    24841 aaactcgtaa tatcggtatc atggctcacg tcgatgccgg taaaacaaca actactgagc
    24901 gtattcttta ctacactggt aaaatccaca aaatcggtga aactcacgaa ggtgcgtcac
    24961 aaatggactg gatggagcaa gagcaagaac gtggtatcac gatcacatct gctgcgacaa
    25021 cagctcaatg gaacaaccac cgcgtaaaca tcatcgacac accaggacac gtggacttca
    25081 caatcgaagt acaacgttct cttcgtgtat tggatggtgc ggttaccgtt cttgactcac
    25141 aatcaggtgt tgagcctcaa actgaaacag tttggcgtca agcaactgag tacggagttc
    25201 cacgtatcgt atttgccaac aaaatggaca aaatcggtgc tgacttcctt tactctgtaa
    25261 gcacacttca cgatcgcctt caagcaaatg cacacccaat ccaattgcca atcggttctg
    25321 aagatgactt ccgtggtatc attgacttga tcaagatgaa agctgaaatc tatactaacg
    25381 accttggtac agatatcctt gaagaagaca tcccagctga ataccttgac caagctcaag
    25441 aataccgtga aaaattgatt gaagcagttg ctgaaactga cgaagaattg atgatgaaat
    25501 acctcgaagg tgaagaaatc actaacgaag aattgaaagc tggtatccgt aaagcgacta
    25561 tcaacgttga attcttccca gtattgtgtg gttcagcctt caaaaacaaa ggtgttcaat
    25621 tgatgcttga tgcggttatc gactaccttc caagtccact tgacatccca gcaatcaaag
    25681 gtattaaccc agatacagac gctgaagaaa ctcgtccagc atctgacgaa gagccatttg
    25741 cagctcttgc cttcaagatc atgactgacc cattcgtagg tcgtttgaca ttcttccgtg
    25801 tttactcagg tgttcttcaa tcaggttcat acgtattgaa tacttctaaa ggtaaacgtg
    25861 aacgtatcgg acgtatcctt caaatgcacg ctaacagccg tcaagaaatc gacactgttt
    25921 actcaggtga tatcgctgct gccgttggtt tgaaagatac tacaactggt gactcattga
    25981 cagatgaaaa atctaaaatc atccttgagt caatcaacgt tccagaacca gttatccaat
    26041 tgatggttga gccaaaatct aaagctgacc aagacaagat gggtatcgcc cttcaaaaat
    26101 tggctgaaga agatccaaca ttccgcgttg aaacaaacgt tgaaactggt gaaacagtta
    26161 tctcaggtat gggtgaactt caccttgacg tccttgttga tcgtatgcgt cgtgagttca
    26221 aagttgaagc gaacgtaggt gcgcctcaag tatcttaccg tgaaacattc cgcgcttcta
    26281 cccaagcccg tggattcttc aaacgtcagt ctggtggtaa aggtcaattc ggtgatgtgt
    26341 ggattgaatt tactccaaac gaagaaggta aaggattcga attcgaaaac gcaatcgtcg
    26401 gtggtgtggt tcctcgtgaa tttatcccag cggttgaaaa aggtttggta gaatctatgg
    26461 ctaacggtgt tcttgcaggt tacccaatgg ttgacgttaa agctaagctt tatgatggtt
    26521 catatcacga tgtcgactca tctgaaactg ccttcaagat tgcggcttca ctttccctta
    26581 aagaagctgc taaatcagca caaccagcta tccttgaacc aatgatgctt gtaacaatca
    26641 ctgttccaga agaaaacctt ggtgatgtta tgggtcacgt aactgctcgt cgtggacgtg
    26701 tagatggtat ggaagcacac ggtaacagcc aaatcgttcg tgcttacgtt ccacttgctg
    26761 aaatgttcgg ttacgcaaca gttcttcgtt ctgcatctca aggacgtggt acattcatga
    26821 tggtatttga ccactacgaa gatgtaccta agtcagtaca agaagaaatt attaagaaaa
    26881 ataaaggtga agactaatcc gtcctcactc tagaaggaag tcacttagtg gcttcctttt
    26941 gtctttagaa aatacctcta aatatggtaa aatagtagaa gaataatgtg aggaaaatga
    27001 atgtcaaata gttttgaaat tttgatgaat caattgggga tgcctgctga aatgagacag
    27061 gctcctgctt tagcacaggc caatattgag cgagttgtgg ttcataaaat tagtaaggta
    27121 tgggagtttc atttcgtatt ttctaatatt ttaccgattg aaatcttttt agaattaaag
    27181 aaaggtttga gcgaagaatt ttctaagaca ggcaataaag ctgtttttga aattaaggct
    27241 cggtctcaag aattttcaaa tcagctcttg cagtcctact atagggaggc tttctctgaa
    27301 ggtccatgtg ctagtcaagg ttttaagtcc ctttatcaaa atttgcaagt tcgtgctgag
    27361 ggtaatcagc tatttattga aggatctgaa gcgattgata aggaacattt taagaagaat
    27421 catcttccta atttagccaa acaacttgaa aagtttggtt ttccaacttt taactgtcaa
    27481 gtcgagaaga atgatgtcct gacccaagag caggaagagg cctttcatgc tgaaaatgag
    27541 cagattgttc aagctgccaa tgaggaagcg ctccgtgcta tggaacaact ggagcagatg
    27601 gcacctcctc cagtggaaga gaaaccagtc tttgattttc aagcgaaaaa agctgcagct
    27661 aaacccaagc tggataaggc ggagattact cctatgatcg aagtgacgac agaggaaaat
    27721 cgtctggtat ttgaaggggt tgtttttgat gtggagcaaa aagtgactag aacaggtcgt
    27781 gttttaatca actttaaaat gacggactat acttcaagtt tttctatgca aaagtgggtt
    27841 aaaaacgagg aagaggccca gaagtttgac ctcatcaaga agaattcttg gctccgagtt
    27901 cgagggaatg tggagatgaa taacttcaca cgcgatttga ctatgaacgt acaggatctg
    27961 caggaagttg ttcactatga gcggaaggat ttgatgccag aaggtgagcg tcgggttgag
    28021 tttcatgctc atactaacat gtcgactatg gatgctttgc cagaggtcga agagattgtt
    28081 gcaacagctg ctaagtgggg acacaaggcg gttgctatca cagaccatgg gaatgtccag
    28141 tcctttccac atggctataa ggcggctaag aaagcgggaa tccagctgat ctatgggatg
    28201 gaagccaata tcgtggagga ccgtgtccct atcgtctata acgaagtgga gatggactta
    28261 tcagaagcaa tctacgtggt ctttgacgtg gaaacgacgg gactttcagc tatctataat
    28321 gacttgattc aggttgcggc ctctaagatg tacaagggga atgttattgc tgaatttgat
    28381 gaatttatca atcctgggca tcccttgtca gcttttacta cagagttaac tggaattaca
    28441 gatgatcatg tcaaaaatgc caaaccacta gaacaagttt tgcaagaatt ccaagaattt
    28501 tgcaaggata cggtcctagt tgcccacaat gctacctttg acgttggctt tatgaatgct
    28561 aattatgagc gtcatgatct tccaaagatt agtcagccag ttattgatac gctggagttt
    28621 gctagaaacc tctatcctga gtataaacgc catggtttgg ggcctttgac caagcgtttt
    28681 ggtgtggcct tggaacatca ccacatggcc aactacgatg cggaagcgac tggtcgtctg
    28741 cttttcatct ttatcaaaga ggtagcagaa aaacatggtg tgaccgattt agctagactc
    28801 aacattgatc taatcagtcc agattcttac aaaaaagctc ggatcaagca tgcgaccatc
    28861 tatgtcaaga atcaggtagg tctaaaaaat atctttaagc tggtttcctt gtctaatacc
    28921 aagtattttg aaggagtgcc acggattccg agaacggttc tagatgccca tcgagagggc
    28981 ttgattttag gttcagcctg ttcagagggt gaagtttttg acgtggtcgt ttctcaaggt
    29041 gtggatgcgg cggttgaggt ggccaagtat tatgacttta tcgaggtcat gccaccggct
    29101 atctatgcgc ccttgattgc taaagagcag gtcaaggata tggaggaact ccagaccatt
    29161 atcaagagtt tgatagaggt tggagaccgc cttggcaagc ctgttttggc tacgggaaat
    29221 gttcactata tcgaaccgga agaagagatt tatcgtgaaa ttatcgtccg tagtttggga
    29281 cagggtgcga tgattaaccg aactatcggt catggtgaac atgcccaacc agcaccactt
    29341 ccaaaggctc attttcgaac gactaatgag atgttggatg aatttgcctt tttgggagag
    29401 gaactggctc gtaaactggt tattgaaaac accaatgcct tggcagaaat atttgaaccc
    29461 gttgaagtcg ttaagggtga cttgtatacg cctttcatcg acaaggctga agaaacagtt
    29521 gctgagttga cctataagaa agcttttgag atttatggaa atccgctgcc agatattgtt
    29581 gatttgcgga ttgaaaaaga attaacatcc atactgggga atggatttgc tgtgatttat
    29641 ctggcatcgc agatgctggt gcaacgttct aatgaacggg gttatttggt tggttctcgt
    29701 gggtctgtcg gatctagttt cgttgcgacc atgattggga ttacggaggt caatcctctc
    29761 tctcctcact atgtctgtgg tcagtgtcag tacagtgagt ttatcacaga tggttcgtac
    29821 ggttcaggat ttgatatgcc ccataaggac tgtccaaact gtggtcacaa actcagtaaa
    29881 aacggacagg atattccgtt tgagaccttc cttggttttg atggggataa ggttcctgat
    29941 attgacttga acttctcggg agaagatcag cctagcgccc acttggatgt gcgtgatatc
    30001 tttggtgaag aatatgcctt ccgtgcggga acagttggta cggtagctgc caagactgcc
    30061 tatggatttg tcaagggtta cgagcgagat tatggcaagt tttatcgtga tgcagaagta
    30121 gaacgcctcg ctcaaggagc ggcgggtgtc aagcggacaa caggccaaca cccgggggga
    30181 atcgttgtta ttccgaacta catggatgtc tacgatttta cgcctgtcca gtatccagca
    30241 gatgatgtca cggctgaatg gcagaccact cactttaact tccacgatat cgatgagaac
    30301 gtcctcaaac tcgatgtact gggacatgat gatccgacca tgattcgaaa acttcaggat
    30361 ttgtctggta ttgaccctaa taaaattcct atggatgacg aaggcgtgat ggcactcttt
    30421 tctgggactg atgtgctagg ggtaacacct gaacaaattg gaacgcctac gggtatgttg
    30481 gggattccag agtttggaac aaatttcgta cgtggaatgg tagacgaaac ccatccgaca
    30541 acctttgcgg aattgcttca gctgtctggt ctgtcccacg gtactgacgt ttggttgggg
    30601 aatgctcagg atctgattaa gcaaggaata gcggacctat cgactgttat cggttgtcgg
    30661 gacgacatca tggtttacct catgcatgcg ggtctggaac ctaagatggc ctttactatt
    30721 atggaacggg tacgtaaggg tttgtggcta aagatttcag aagaggagag aaatgactat
    30781 atcgaagcca tgaaggctaa taaggtgcca gagtggtata tcgaatcctg tgggaaaatt
    30841 aagtacatgt tccctaaggc ccatgcggca gcctacgtta tgatggcctt gcgtgtagct
    30901 tacttcaagg ttcaccatcc tatttattac tactgtgctt acttctccat tcgtgctaag
    30961 gcttttgata tcaagaccat gggtgcgggc ttagaggcca tcaagcgcag aatggaagaa
    31021 atctctgaaa aacggaagaa caatgaagcc tctaatgtgg aaatcgatct ctatacaact
    31081 cttgagattg tcaatgagat gtgggaacga ggtttcaagt ttggtaaatt agatctctac
    31141 tgtagtcagg cgacagagtt cctcatcgac ggggataccc ttatcccacc atttgtagca
    31201 atggatggtc tgggagagaa cgttgccaag caactggtgc gggcgcgtga agagggagaa
    31261 ttcctctcta aaacagaact acgcaagcgt ggtggactct catcaacctt ggttgaaaag
    31321 atggatgaga tgggtattct tggaaatatg ccagaggata accagttgag tttgtttgat
    31381 gagttgtttt aaaaaattgc ttaataatct attaaaagag gctaacgtat atccaataga
    31441 tttacattag ctttcttttt tgttaaaata gtctatggaa agagggtgag agtatgtcaa
    31501 agatgagtat aagcatccgt ctggatagtg aggttaagga gcaggcccaa caggtgttta
    31561 gtaatctggg aatggatatg acaacagcta ttaatatttt ccttcgtcag gcaattcaat
    31621 atcagggact accttttgat gttagactag acgaaaatcg gaagttgctc caagtgttaa
    31681 cggatttaga ccaaaatcgt aatatgagcc agtcttttga atcagtctca gatttgatgg
    31741 aggacttacg tgcttaagat tcgttatcat aaacagttta aaaaagattt taagttggct
    31801 atgaagcgtg gtttgaaggc agaattatta gaagaagttt tgaattttct ggttcaagaa
    31861 aaagaacatc ctgccagata tcgtgatcat tcattgacgg catccaagca ttttcaagga
    31921 gttcgtgaat gctataccca gccagattgg cttttggttt ataaagtaga caagtcggaa
    31981 ttgattttaa atttgctgag gacaggcagt cacagtgatt tattttaatc tattttaagg
    32041 gggttctcat gaaactaaga atatttgcgg aagataagcc ggctaagaag gtatttgaat
    32101 atcaattaga acttgctgat cgtacaattc ttctatcgac agcactcttg tcaggtgcta
    32161 ttgctttagc aggaatcttt tctgctttga aagaaaaata aaaatagaaa agagaaaaca
    32221 ggatggtttt accaaatttt aaagaaaatc tagaaaaata tgcgaaattg ttggttgcga
    32281 acggaattaa cgtgcaacct ggtcacactt tggctctctc tattgatgtg gagcaacgtg
    32341 aattggcaca tctaatcgtg aaagaagctt atgccttggg tgcgcatgag gtcatcgttc
    32401 agtggacaga tgatgtgatt aaccgtgaga aattcctcca tgccccgatg gagcgtttgg
    32461 acaatgtgcc agaatacaag attgctgaga tgaactatct cttggagaac aaggctagcc
    32521 gtcttggagt tcgttcatct gatccaggtg ccttgaacgg agtggacgct gacaagcttt
    32581 cagcttctgc taaagctatg ggacttgcca tgaagccaat gcgaatcgca actcaatcta
    32641 acaaggttag ctggactgta gcagccgctg ctggacttga gtgggctaag aaagtcttcc
    32701 caaatgctgc gagcgacgaa gaagcagtcg atctcctttg ggaccaaatc ttcaaaactt
    32761 gccgtgtcta cgaagcagat cctgttaagg cctgggaaga gcatgcagcc attctcaaga
    32821 gcaaggccga tatgcttaat aaggagcaat tttcagccct tcactacaca gcgccaggaa
    32881 cagatttaac acttggtttg ccaaagaacc acgtttggga atcagctggt gctgtcaatg
    32941 cacagggcga aggattcttg ccaaatatgc cgacagaaga agtcttcaca gcgccagact
    33001 tccgtcgtgc agatggttat gtaacctcta caaaaccgct tagttataac ggaaacatta
    33061 ttgaaggtat taaggtgacc tttaaggatg gacaaatcat agatattact gctgagaagg
    33121 gtgatcaggt tatgaaggat cttgtctttg aaaatgcggg tgcgcgtgcc ttgggtgaat
    33181 gtgccttggt accagatcca agcccaattt ctcagtcagg tattactttc tttaacactc
    33241 ttttcgatga aaatgcgtca aatcacttgg ctatcggtgc agcctatgcg actagcgtcg
    33301 ttggtggagc agagatgagt gaagaagagc ttgaagctgc gggacttaac cgttcagatg
    33361 ttcacgtgga ttttatgatt gggtctaatc agatggatat cgatggtatc cgtgaggatg
    33421 gaactcgagt acctcttttc cgtaatggga attgggcaag ttaaggagat aatatgttag
    33481 gaagtatgtt cgttggtctc ctagtgggat ttttagcagg tgctatgacc aatcgtggag
    33541 agcgaatggg atgttttgga aaaatgtttc tcggttggat cggagccttt ctaggtcact
    33601 tgctctttgg aacttggggg ccagttttat caggaacagc tattatccca gcgattttag
    33661 gagccatgat tgttttagct attttttgga gacgaggaag ttaatttcct aaatctgata
    33721 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa agtactgctt
    33781 tgaggttgca gatagaactg acgaagtcag ctcaaaacac tgttttgagg ttgcagatag
    33841 aactgacgaa gtcagtaaca tatatacggc aaggcgacgt tgacgcggtt tgaagagatt
    33901 tttgaagagt atgaaacgaa aaggaggttg gtcattgtac tagcctcctt ttgatatgat
    33961 ataatagttc tatgagatta gataaatttt tagttgcctg tgcggtggga agtcggactg
    34021 aggtcaaaaa cttgctcaag gctgggcgcg tgactgtaaa tggtaaaaaa gaaaaatcag
    34081 ctaaattgca gattgatgaa aaaatagatg agattcgctt tgatgggcaa gtgttggagt
    34141 atgaagagtt tgtctactac atgatgaaca agcccaaagg agttatctca gcgactgagg
    34201 atcccaagca cagaaccgtt ctggacttgt tggatgactt ggcgcggagt aaggaagttt
    34261 tcccagtagg acgcttggat attgacacgc atggtctttt gctcttgacc aatgatggtc
    34321 agctggctca tgttcttctt tcgcccaagc gtcatgtgga caagacttat ctggcacaag
    34381 tcaagggaat catgacccaa gaagatgtgg agacatttgc tgagggtatt cttctcaaag
    34441 actttacctg tcaacccgct atactggagc ttgtatccat agatacagaa aagaatcaaa
    34501 gccaaatccg tgtgaccatt gcagaaggga agtttcatca gatcaagcgt atggtgggct
    34561 actgtggcaa ggaagtggtg gacttgcaac gattgactat gggaacttta gtattagatg
    34621 agaacctaga acgaggggaa tggcgtcgct tgaccaagga agaattagaa attctccgcg
    34681 ctaatattat ttaatttagt ttaatactca atgaaaatca aagagcaaac taggaaacta
    34741 gccgcaggct gtacttgagt acggcaaggc gacgttgacg tggtttgaag agattttcga
    34801 agagtataaa ttcgaaaaag gtgagggaca atgtcctcgc cttttatgtt ttttagttgc
    34861 ttcctttgtg aaaagagtta taatagactg tagaataaaa ggaggaatct atgaacgcga
    34921 ttcaagaatc atttactgat aaactatttg ccaactatga agcaaatgta aaataccaag
    34981 cgattgaaaa tgctgccagc cacaacggaa tttttgcagc tctggaacgt cgccaaagcc
    35041 atgtagacaa cacacctgtt ttctcattgg atttaaccaa ggacaaggtc actaaccaga
    35101 aagcgtctgg tcgttgctgg atgtttgcgg ctctcaacac cttccgccac aaactcatct
    35161 cgcaatacaa attggagaac tttgagttgt cacaagccca cactttcttc tgggataagt
    35221 atgagaaatc aaactggttc ttggagcaag tcattgcgac ttcagaccaa gaattgacta
    35281 gccgcaaggt tagcttctta ctccaaacac ctcaacaaga tggcggtcaa tgggatatgg
    35341 tcgtttccct ctttgaaaaa tacggtgtcg tgcctaagtc agtttatcct gagtctgttt
    35401 catctagcag cagtcgtgag ctaaatgcga tccttaataa attgcttcgt caagatgctc
    35461 aaatcttgcg tgacttgctt gtttctggtg cagatcaagc gactgttcaa gctaagaaag
    35521 aagacctctt gcaagaaatc tttaactttc ttgctatgtc attgggactt ccaccacgca
    35581 agtttgactt tgcttatcgc gataaagata acaactacaa aagtgaaaaa ggaatcacac
    35641 cacaagagtt ttacaagaaa tatgtcaatc ttcctttaga agactacgtt tctgttatca
    35701 atgctccaac tgctgataaa ccttacggaa aatcttacac agttgagatg ttggggaatg
    35761 tggttggtag ccgtgcagtt cgctacatca acgttccaat ggagcgcttg aaagaattgg
    35821 cgattgccca aatgcaagca ggtgagactg tttggtttgg ttctgatgtc ggccagctca
    35881 gcaaccgtaa ggctggcatc cttgcgacag atgtttatga ctttgaatca agcatggaca
    35941 ttaaacttac tcaagacaag gctggacgtt tggactatag tgaaagcttg atgacccacg
    36001 ccatggtctt gacaggtgtt gacttggacg aaaatggtaa atcaaccaag tggaaggttg
    36061 aaaactcatg gggagacaag gtcggtacag atggttactt tgttgcctca gacgcttgga
    36121 tggacgaata cacataccaa atcgttgttc gtaaggaatt gctgacagca gaagaacaag
    36181 ctgcctatgg agcagaacca atcgtacttg caccatggga tccaatggga gccttggctg
    36241 aataaaagca tagaaaaaag gaatcagatt ttagaacctg gttccttttt agttgcttga
    36301 ttacatgatg tgaagaacat gtgccacaat acccactgcg aagagggcaa ggataatagt
    36361 gattggagat acttttttct taagtaagta catgcaaagt aaagtaagga gtagtcctga
    36421 taatccagga atcaacatat ccaagttttg ttggaaagta gtaacttttt caggagtttg
    36481 agacaatcct tgtcctactt gtgcgaatgc ttcttggata cctttagacc cttctggcaa
    36541 tttatcccaa tggatataag ccttttcatc tagttgaact ttagaaacat cgaaagcaaa
    36601 tttaatattt acccagcgtt gaacaaggac agcaagaatg aacatcccaa ggatagaagc
    36661 tcctttagtg atatcttgaa ggataccacc agacatatct ttagtgattt ctgatccagc
    36721 cttgtatcca atctcttgaa cataccacaa gaatgacata cgaatcaagt tccatgcaac
    36781 aaagaagagg agtggcccca agatattgcc agtaagggca agtgaagcac cgagagatcc
    36841 aaggattggg cgtactgtaa accagaatac tgggtcaccg ataccggcaa gaggtcccat
    36901 cataccgatt ttaacccctt ggatagcagc gtcatcgatt tccacaccgt tagcacgttc
    36961 ttcttcaagc gcaagagtaa cccccatgac tggagcagct acgtatggat gagtgttgaa
    37021 gaactcaagg tgacgttcaa gagcagcgat ttgatcttct tttttagtat agagtttttt
    37081 gatagctgga atgagtgtat aagcccagcc caagttttgc atccgttcaa agttccaaga
    37141 cccttgtaag aaggttgaac gccaccaaac ttttttacga tctgatttag ttaattgaag
    37201 tttttcagtc atgatgtttt cagtcctttc ttatcttagt agtcttctag gatatcgccg
    37261 attgggtcgt tagaagttgc ggctcctccg ccaccatttc caccagtttt agaaaggtga
    37321 aggtagataa gagcgatagc aacaccgata gcaccgaatc cgattagagt aatatctgac
    37381 acagcagcga gaacgaaacc aagagcgaag aatggccata cttcacgagt tgccatcatg
    37441 ttgataacca tggcgtaacc aacggcaacg accataccac caccgatagc cataccatct
    37501 ttgagccagt ctggcatggc actaaggata ctttgtacag tttcagttgg taccataagg
    37561 agaagagctg caggaagcgc gatacgaagt ccttggaaga gtagcgcaat gaaatgcgca
    37621 cgctccacag cgccgaagtc acctttttta gcggcagcat ctgcagtatg aaccaaacca
    37681 actgaaattg tacgaacaat cattgtcaag aaaagtccag ctacggcaag agggatagca
    37741 accgcttggg caacaccgat accagtcttg gtaaagtcac caccaagaac catgataatg
    37801 gcagcagcga cagaagcaag tgcagcatca ggagcgatag cagcaccgat atttgaccaa
    37861 ccaagggcaa tcatttgaag cgatccaccg aggataatcc ctgcttccaa gtgacctgtt
    37921 acaagcccaa taagggtaca ggctacaagt ggttggtgaa attggaactg gtcgaggatg
    37981 ccttcaagac ctgcaaagaa ggctacaacg actactaaaa ccatagaaat aatagacatg
    38041 tttaaaatcc tttcataaat aatggcttat ttgacattgg ctttgttaat caagtcaaac
    38101 aaatcttttt tagaatcatt tggtacttta cggacatcaa attcaacacc caagtcacgc
    38161 attttttcaa atgtagcaac atcttctttg tccatagaca aaacggtatt gaccaatgtt
    38221 ttacctgttg agtgagccat agaaccaacg ttaagagtct tgattggcac gccaccttcg
    38281 atggcacgaa gggcatcttg aggtgtttca aacaagataa gggcatgtgt ttctccaaaa
    38341 cgtgggtctt ttgaaatctc aatcagtttt tgaattggaa ccacgttagc cttgacatta
    38401 cctggagctg cttgtttaat caattcttta cgaaggtcgt ctttagccac gttatctgaa
    38461 gcaacgatga tacgatttgc ttttgaatct ggagtccaag cagttgcaac ctgaccgtga
    38521 agtagacgtg tgtcaagacg ggcaagattg attttcaatt taccgtctcc gataacagtt
    38581 ccttctggga tagcagtttg ggcaactgga gcagctgcag cgcttgcaac ttcttcaact
    38641 ggatttagct cttctggaag agctttgatg ccatctttgg cttctttaat gatattagca
    38701 gcgacttttt ctacacctgc agcagcgtcc atgaggcgct ctgtgtaggc ttgaatcaac
    38761 atcggtaagt taagtcctgt gatgatggca aacttacgct caggattttc tcccatcacg
    38821 cgactagctt ggttaaatgg agaaccactc caaaggtcag ccaaaactag aacctcatct
    38881 tctgcgtcaa atgcagcaac agcgttatta aacttagtgt atagatcatc aggaccttca
    38941 tttggcataa aggtcacaac ttgaaccttt tcttgttcac caaagatcat agatcctgac
    39001 tgatgaatac ccgcagcaaa ttcgccgtgg ctcgcaataa tgattccgat actcattatt
    39061 gtcattcctc cttttttgtt ttagttttca tttaagaaaa ctttaagact gtttaagtat
    39121 aaaccgtttt cataaaaaaa gcaactattt atcataaaaa attaaaaaat ttttattttt
    39181 gtatgttgat atgttgagtt tttgaggagt aatcttgaat tcttatttaa aatttaatat
    39241 aaa
//
LOCUS       DAVEHY010000019        38640 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVEHY010000019 DAVEHY010000000
VERSION     DAVEHY010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38640
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.019"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(91..228)
                     /locus_tag="VUZ44_001194"
     CDS             complement(91..228)
                     /locus_tag="VUZ44_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320110.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEVLNIRLEVK
                     N"
     gene            486..605
                     /locus_tag="VUZ44_001195"
     CDS             486..605
                     /locus_tag="VUZ44_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU0320111.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="VUZ44_001196"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="VUZ44_001196"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU0320112.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="VUZ44_001197"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="VUZ44_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU0320113.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="VUZ44_001198"
     CDS             complement(2517..3044)
                     /locus_tag="VUZ44_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU0320114.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFIGVFVAIIVN
                     YDIDRIRLFLEKKGK"
     gene            complement(3180..4376)
                     /locus_tag="VUZ44_001199"
     CDS             complement(3180..4376)
                     /locus_tag="VUZ44_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU0320115.1"
                     /translation="MAKLTVKDVDLKGNKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4466..9406)
                     /locus_tag="VUZ44_001200"
     CDS             complement(4466..9406)
                     /locus_tag="VUZ44_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU0320116.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETAEAASAAKPEEK
                     VGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAEEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTVQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTSDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFSDVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGH
                     EVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHIIFTAPHFTHYAFVYESAEKPQPAKPAPQNT
                     VLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            9695..11326
                     /locus_tag="VUZ44_001201"
     CDS             9695..11326
                     /locus_tag="VUZ44_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU0320117.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNIIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11885..13492)
                     /locus_tag="VUZ44_001202"
     CDS             complement(11885..13492)
                     /locus_tag="VUZ44_001202"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU0320118.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13882..14469)
                     /locus_tag="VUZ44_001203"
     CDS             complement(13882..14469)
                     /locus_tag="VUZ44_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU0320119.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14597..15046)
                     /locus_tag="VUZ44_001204"
     CDS             complement(14597..15046)
                     /locus_tag="VUZ44_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320120.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15051..15440)
                     /locus_tag="VUZ44_001205"
     CDS             complement(15051..15440)
                     /locus_tag="VUZ44_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU0320121.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15468..16094)
                     /locus_tag="VUZ44_001206"
     CDS             complement(15468..16094)
                     /locus_tag="VUZ44_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU0320122.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16108..16671)
                     /locus_tag="VUZ44_001207"
     CDS             complement(16108..16671)
                     /locus_tag="VUZ44_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU0320123.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16836..17070)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17124..17627)
                     /locus_tag="VUZ44_001208"
     CDS             complement(17124..17627)
                     /locus_tag="VUZ44_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU0320124.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17820..18650)
                     /locus_tag="VUZ44_001209"
     CDS             complement(17820..18650)
                     /locus_tag="VUZ44_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU0320125.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATIFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18635..20317)
                     /locus_tag="VUZ44_001210"
     CDS             complement(18635..20317)
                     /locus_tag="VUZ44_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320126.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20419..20631)
                     /locus_tag="VUZ44_001211"
     CDS             complement(20419..20631)
                     /locus_tag="VUZ44_001211"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320127.1"
                     /translation="MKIKEQTRKLAAGCSKHGFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(20638..21186)
                     /locus_tag="VUZ44_001212"
     CDS             complement(20638..21186)
                     /locus_tag="VUZ44_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU0320128.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21201..22049)
                     /locus_tag="VUZ44_001213"
     CDS             complement(21201..22049)
                     /locus_tag="VUZ44_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU0320129.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22237..23586
                     /gene="trkA"
                     /locus_tag="VUZ44_001214"
     CDS             22237..23586
                     /gene="trkA"
                     /locus_tag="VUZ44_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU0320130.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23590..25029
                     /locus_tag="VUZ44_001215"
     CDS             23590..25029
                     /locus_tag="VUZ44_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU0320131.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLITLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25154..26833)
                     /locus_tag="VUZ44_001216"
     CDS             complement(25154..26833)
                     /locus_tag="VUZ44_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU0320132.1"
                     /translation="MGKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDISAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWTFPGPLGLLIGTNF
                     QLISFVFLSLILVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGTQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(26902..28314)
                     /gene="lacG"
                     /locus_tag="VUZ44_001217"
     CDS             complement(26902..28314)
                     /gene="lacG"
                     /locus_tag="VUZ44_001217"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU0320133.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(28324..28668)
                     /locus_tag="VUZ44_001218"
     CDS             complement(28324..28668)
                     /locus_tag="VUZ44_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU0320134.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(28836..30722)
                     /locus_tag="VUZ44_001219"
     CDS             complement(28836..30722)
                     /locus_tag="VUZ44_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU0320135.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(30724..32046)
                     /locus_tag="VUZ44_001220"
     CDS             complement(30724..32046)
                     /locus_tag="VUZ44_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU0320136.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            32213..33436
                     /locus_tag="VUZ44_001221"
     CDS             32213..33436
                     /locus_tag="VUZ44_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU0320137.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            34088..34258
                     /locus_tag="VUZ44_001222"
     CDS             34088..34258
                     /locus_tag="VUZ44_001222"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320138.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            34870..35154
                     /locus_tag="VUZ44_001223"
     CDS             34870..35154
                     /locus_tag="VUZ44_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320139.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            35147..35395
                     /locus_tag="VUZ44_001224"
     CDS             35147..35395
                     /locus_tag="VUZ44_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320140.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            35491..35709
                     /locus_tag="VUZ44_001225"
     CDS             35491..35709
                     /locus_tag="VUZ44_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320141.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(36077..38401)
                     /gene="pflB"
                     /locus_tag="VUZ44_001226"
     CDS             complement(36077..38401)
                     /gene="pflB"
                     /locus_tag="VUZ44_001226"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU0320142.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT        11756 a         8255 c         6760 g        11869 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 aacctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttggcaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattag tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttgaaattg aatttttcca tagtgactcc ttaattttct
      541 tctacacgtc tgatgataaa tctaattcgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acgaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaagct agtatagatg tgatctccga gagcagcttt aaccacttca tcttctgtca
      841 aagctttcaa agcgttgtga agagttgatg gaaggtctgt aataccagct tccttgcgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccata caaaccaact tccaaaagaa cagccatagc aacgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatagcagt atagttgtaa gcatgcttga
     1201 tcaaaccgcc taggaaatgg taagctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgcat caaacaagga catattacag tgcatacctg
     1321 atccagcaat accaaatttt ggcttcgcca taaatgttgc gtaaagtccg tgtttgcgag
     1381 caatggtttt aacaacaagc ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 cgtacttaaa gtcaatctca tgctgtccaa ccgcaacctc gtggtgactc gcttctactt
     1501 caaatcccat tttggtcaag acattcacaa tctcacgacg tgtgttgtcc gcaaggtcag
     1561 taggtgccaa atcaaagtag ccacccttgt cattcacttc aagtgttggg tccccatttt
     1621 catccaactt aaataggaag aattctggct ctggaccaag gttgaaggat ttgaatccaa
     1681 cttcttccat gtgacgaaga gctcgtttca aattaccacg agggtcaccc gcaaatggtt
     1741 caccttctgt tgtatagaca tcacagatca gacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtccg ggtacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acataacctt gttcgacaag accttatcta
     1921 actgttcatc tgtagcagga atttcgacgt ttttcatggt tcccaaaata tctgagaaca
     1981 taagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcataag ttttctcctt aatctatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaaa cgcccctgtt ggaggagttc attgtgaagt gcacgacgta
     2161 cttcagtctg actaaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 cttcataata acgaatctga cgcgccgata gatcggtcaa cttcataaca ctgccaatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattgataat gttataaaat gtaacattat
     2521 tttccttttt tctctaaaaa gagacgaata cgatcaatat cgtaatttac gataattgcg
     2581 acaaaaactc ctataaacgt ttctgataca cgcacaaaca cgtacgaaat tgtctcacca
     2641 cttggaattg atagggtaat gattaacata gctgctacac caccaataac ccctgctttg
     2701 ttattcatgg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga agaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctc atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaag
     2941 ccaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttgaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactctcatc cctctcttct ttgatttgtt tataaaatct
     3181 tatttttctg tcaaggctgc aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccaa ttgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atgtcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccgatt
     3661 tcgatacctt gtgctttgta gaatgtgtaa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg agataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgcttccaat
     4081 tcagcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtca
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattacg ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga ctttgttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattcgaaa ctattatatc acactttgga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctagact agcaagacca aggctggcta agcctgctat tagggcttca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccgtttt
     4741 catcaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcgttgtt
     4801 ccccaactag catctcagta ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagtcgg ttgataagta ggttttggaa
     4921 ggactgtgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtga ggtgctgtaa agataatatg actatccgtt tgttcaaaag
     5041 ccaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcat aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaac ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tggcttgtct tctttcaata
     5341 aagcaaccag atcttttaga ctctgtttcg ctgttgtaag ctcttctgga ctcaaatcta
     5401 ctttttcaac caaggccttg tttttctcaa gaagcggagc tagggcagaa cctgaaggat
     5461 ggtttggttt ggcagccaag agttcttgaa cctcacctgt taagcgatca agctctgtct
     5521 tttcttccgt aaatttctct tgaccattca gagctttatg agcttctgtc aatttattaa
     5581 gtcggtcatt gacttgatct tgggtgctag tttcatggtc tttcaacact tgttcggccg
     5641 cttcaattgc tttcaagaag gcttctttta cttctgatga agcaaagtta tagaccacct
     5701 tgttcttagc agcttcaact tctgctaatt tttgtttgag gtactcatcg ttcaatgctg
     5761 cttttggaga taccaaaaca tcaaagctaa cttcatggcc ttggtaatga agcgtcaagg
     5821 tttgacgacc agtcttttga gcatcgtaac cagaaatttc aactccctca tcagtaaagg
     5881 aatgttcttc catggtgtca ttgctataag ccactgcaaa gcgtccttca gacaagtcta
     5941 agctatcacc aactaggtaa tcttttttcg gttcctgact tacttcaatt cccaaaatag
     6001 ttttcggact tgcttcgtct tggccagtga cagtcactga caaattagca tttaccggtt
     6061 gtcccaaata ttggagagta agattctgtt ctcccttatg atgcgtatca aaacctgata
     6121 ctgatacacc tgcgtgagtt aggcgaatga gttcgtcctc agttcctcct tcatactgaa
     6181 ctcgaagaac accacctcta aggtccaaat cctccccttc ggcgtagctt gttttcttag
     6241 gtcctgtttc taggctgact gacttgattc ttctgtcatc ttttggaacg gaaactgcta
     6301 ggacattact aatttccttg cctggcaact gggtacgata ataaagaaga ccagattgat
     6361 ttgtcaaatc caatggtgca cttgctaggt ctcctccaac ttcgctcttc aaggttgcaa
     6421 gcggagtttg agaatttgga ttatcataaa cagtaatagt tgctccagcc ggtacatctg
     6481 aaaagccaac ttgtaccttg ttattgccta gagaacgggc tgcagccttg gccatcggaa
     6541 tattgacact ctcagtatca agcttttcat acattttcca gttatagata cgaatagcct
     6601 tccatggagt tccattgtca gaagtgacaa cattcaagcg ccagtcttga gcagtgattg
     6661 gtttatcaag agtgatatct gtcacgtgtg ctttgttacc acggacttcc ttagctagct
     6721 tccactcacc atctgcatct ttataataaa ggtcaaagtc tttggtgttc atcaagccat
     6781 cgttaacaga ctcaccacca gcccctgcat gatccatgac ccatctaaca acggtacgtg
     6841 gcttggtcaa acgaatatcc acactaccac tcaactgagc tgaagaccat ttatctgaca
     6901 agctagtaat ggtaccgttc aacatacctt caataccttc tccgccttca gtcttaggga
     6961 aagtactatc aataactgtt gcacctggaa cgatattttc agctagtggt tttggtaggc
     7021 tggtatcttt tacagtcata ccccaatcaa aggttgtggt tgcagcttct gaacgaactc
     7081 catttttacc gactgctaca accttcagtt cttgagttgt accctgagca cttgctgagc
     7141 ggctaacttt tggtagataa atagttgtag aagatgagcc agttagtaat ttccagctgt
     7201 ctccatcttt ttcataaact tcatagaaat ctgcatcctt gttgccttta aattgcacaa
     7261 ctgcttccgc ttcttgggca tttttaagag attgtttcac tacagaaaag cttgtcggcg
     7321 attgtggctc ttggtgattg tccgagatag ttaattgtcc gaggttgaac tgataatctt
     7381 ttacagcacc ttcatgctcg aaaaatagtt tgactgcata gatggtttta cctgctagtg
     7441 agctgagatc aaattcttca tttgtccagt tgtcagaaag ggttagctct ttccatgcat
     7501 ctgcatcatc gaatttgtag tctgaagttg tagagaatgc catataaact ttagaacctt
     7561 ttcctccctt gtgggcaaca cgaagtttgg tcttctcagt tacttctaac ttagtagaat
     7621 aaagtctcac atcctgaact gtcttaccgg ctacatcacc agagaattta agggaatttc
     7681 cgccattata ggcatctgta aaatcatatt ctgcacgaag tttttcccct gttgaagtct
     7741 gccaccagcg ccatgttgga agaacacctg atactgaacg ataattccac tcagaatcct
     7801 tagaaacctt accatctacg aaccattttt taccatgacc tgtattaaaa gaagtagtaa
     7861 aagtattacc taccgctggc gtacggtccg caactaggtt agcaatacca taccaatctt
     7921 tgtcacctgg tttttggcca gtggggtctc cttgataacc tgtaaagaag atatcttcat
     7981 ttttatgata atcttcacca gtttttccta aacttgtaat ggtatctggg gcaaataaac
     8041 caagagaaag gcgcaatttc ccattttcgt ctaaaatgtc attccactta acctttgtct
     8101 tgtaggaacc accctgttgc aattccaaac ctgcaaatac atcataagga ttacgaccaa
     8161 tccagttggc agttgcaata gtgtaatcat ttttagcctt atcccagtta aagttagcaa
     8221 agaagttatc tgccggaacc ttatctcctt ctggttgcat gaattggtag ttgtattctc
     8281 ccaaaccatc ttgatggtaa cgtccatagt tataggtcat ggcatcatac caagaatact
     8341 tgattggatg gtttacctta gcagcatatt ccttgctata gagcataaac tggcgcatct
     8401 tttctccaag aggtttaacc aaatctccag ttgtttcttg gttgatgaaa tagccatcat
     8461 agccataata cttggccatg tctaccaatt tacgggcaat tgggaagcta ccatctgcgt
     8521 cttgcttcaa agcttcagca aatctttctt gatctgcaat actattagac cagttgaaga
     8581 agagtgtacc gtatacagga accccgttac ggtgacctgc atcaataacg tcaggagttg
     8641 gtacgagacc ttcccagaag accattgaat ctagatattg ccaatagtca aaagcatagg
     8701 ccttgaactc ttctccacca acagaagcat ggtcttttgc tttagaatta gtgtttgata
     8761 aggcttgaac ttttgcttcc ttgctagctt tttcattgac taaatgacct gtccgacgtg
     8821 aagcgaggac aacagatccg cggttaatag catcatcttc acgagcacct ggttcccatt
     8881 ttaacaattc ttcccaagaa ttaaatttga tttcctttgg ttttaatgtt ttttctgtat
     8941 ttttagggac atctggctgg acttcttttt cagtcttatt agcttcttct gctggtttag
     9001 actcatcccc ttggttagtt gcttcgggct ttgcttctgt ttccttgtca gacttaggtt
     9061 ttgcttctgc agatggtgtt tctgcaacca cctcacctac tttttcctct ggtttagctg
     9121 cgctagctgc ttctgcagtt tcagatgctg tcgctactcc ttctgccttt tctagcttgt
     9181 tttctctagc atgttcccct tcattctgct tatcagcttc attggtcgaa tgctcactct
     9241 ctcctgaaac aagctctgta ttagctccgc tattttcagg aactgcagtt tcttcagcca
     9301 aggctggacc agcaaataaa acagcaccaa tcatcagcga gcaggctcct actgataact
     9361 tacgaatact gtaacgacaa cgtctttcaa aaaatggatt cttcattttc tcctcctaaa
     9421 agattgattt tgttgttttc aagaaagcgc tttatattct gtagtttttt aactctagaa
     9481 tcatgataat cacattttta tcctaaaaca tttttagaca aaaaacaata gctgttttca
     9541 caaatctaaa ataaggttaa aaactcttaa aaataataca cttatcaatt ataattttct
     9601 tttacaaact tgacattaac acttgttaga tttactttta tcctttaaaa tagaatagga
     9661 gatattccgc gattattttt cggaggaaaa agaaatgtcc attaattggc aggaaatttt
     9721 atttcacttt ttaggtggtc tggggctatt cttatatagc atcaagacca tgggagacgg
     9781 tttacaacaa gctgctggag atcgccttcg tttttacatt gacaaatata ctagtaatcc
     9841 tttctttgga gttctggttg gtattgggat gactgctcta attcagtcta gttctggtgt
     9901 aacagttatc acagtcggcc tggtcagtgc cggtctctta accttacgtc aggctatcgg
     9961 gattgtcatg ggtgctaata ttgggacaac tgtcacatcc tttctcatcg gttttaaatt
    10021 aggtaactat gccctaccta tgctctttat cggtgccgtc tgtctctttt ttacaaaaaa
    10081 tcggacagtc aataatatcg gacgcatcct ctttggtatc ggtggtatct tttttgccct
    10141 caatctcatg agcggcgcaa tggctccact caaggattta caggtcttta aggactatat
    10201 gattgagcta agtaagaatc ctgttttggg tgtctttgtc ggtactggct tgaccttgct
    10261 aattcaagct tcttcggcta ccattgggat tttacaaaac ctctacgccg gcaatctaat
    10321 tgacctacag ggagctttgc cagttctatt tggtgacaat atcgggacaa ccattacagc
    10381 catcattgcc tctttagggg ctaatattgc agctaaacgg gtagcaggag ctcatgttgc
    10441 cttcaacatt atcggaacag tcgtctgcgt tatttttcta gttcctttta ctgtcctgat
    10501 tcattggttt gaagctacgc taaatctagc accggaaatg accatcgcct ttgctcacgg
    10561 aacctttaat attaccaaca ccattgtcca atttccattt atcggagctc tggcttactt
    10621 tgtaaccaag attattcctg gagaggacga ggttgtcaaa tacgaaccct tatatcttga
    10681 tgaacatttc atcaaacagg ccccatctat cgctctagga aatgctaaga aagagctctt
    10741 gcacttagga aactacgctg ctaaagcctt tgacctttcc tataagtaca tcattgactt
    10801 ggatgaaaaa gttgctgaaa aagggcataa aaccgaagaa gcaattaaca ccatcgatga
    10861 gcaattaaca cgttatctca ttgccctttc aagcgaagct ctcagccaaa aagaaagtga
    10921 agtgcttacc aatatccttg attcctcccg tgatttggaa cggattggag accacacgga
    10981 ggctctactc aatctgactg actatcttca acggaaaaat gttgaatttt ctgatgccgc
    11041 cttgaaagaa ttagaggaag tttaccgcca aactagtgac tttatcaaag atgctctgga
    11101 tagtgtggaa aacaatgata ttgaaaaagc acgcagtctt gtagaacgtc atgaagcaat
    11161 caataagata gaacgtgttc tcagaaaaac ccacatcaaa cgcctcaaca aaggcgaatg
    11221 ttcaacacaa gctggagtca actttatcga catcatctca cactacactc gtgtatcaga
    11281 ccacgctatg aaccttgctg aaaaggtttt tgcagaacaa atctaataac caagaagcta
    11341 tccatcataa ttggatggct tcttactttt tcctaagcaa gactaggctg aatgaaactg
    11401 aaagagtatt ctgcagatat ataatatatt gaaactagaa tagtacacct ctatttctaa
    11461 aacattgtta gaaatcgatt tgactgtcct gaacgatttg tcctgttatt atttcatttt
    11521 attatagtgg attaaattaa aaaagtatag tatattgaat ctataacagt ccatcttgac
    11581 tgctaaaata tttctataaa ttaatttgac tttcctgata gagatgttca catcttattt
    11641 caattcacta tacaatccag ttcctaaaac tttgctagaa attgatttgg ctttccgaat
    11701 taatttgttc aaattttatt tcatttcaat atactgataa atccattcac tagcacaggg
    11761 caagagggag tcgctattga tttcaacggt agcaggtaca tacagaggac tcctacctca
    11821 gatatactgc aatatcatcg tatgcaaaaa acctctgaga tttttctcaa aggttctgat
    11881 tttgctaatt gctgttctca accgctgcag taacaaaggc agtgtagagt tcttctggtc
    11941 ggtttggacg gcttgacagt tcagggtgat actgacaagc tacaaagaat ttattttcag
    12001 gaatttccac gatttctacc aaacgattgt ctggagaaac tcctgaaaag acaaaacctg
    12061 ctgcctcaaa ctgctcacgg aaggcattat taaactcata acggtgacgg tgacggcgtt
    12121 gcaccacttc ttgattgtga taagcagcag cagccttaga gccacgtttc aacttagacg
    12181 gataaagtcc caaacgaagg gttccaccca tatcctcaat atcaatctga tcacgcatga
    12241 tatcaatgat agggtatttt gtttctggtg caagctctgc agaattggca ccttcaagac
    12301 ctaaaacgtg acgagcaaac tcgatacatg tcaactgcat tcccaagcag actcccaaca
    12361 ttggaacatc attttcacgc gcatagcgga tggcttggat tttcccttct gtaccacgtt
    12421 gaccaaaacc acctggtacg atgatcccgt ccgcatcaga caagagttct gctacattct
    12481 ctgctgtcac atcattggca ttgacccaat tgattttaac ttctacatca ttgacatagc
    12541 cagagtgttt caaggcttcg accactgaga tataggcatc ttgcaactcc acatacttac
    12601 caacaaggga aatcttaact tgtttcttga ggttcatgac cttgtccacc atggctgacc
    12661 attctgtcat atccgctgct ggtgcgtcta atttcaaatg atcacaaaca atttggtcca
    12721 tcccttgtgc ctgcaagttc agtggaattt ggtaaaggtg ttcaacatcc aacgattcga
    12781 taacggcttc tggtgccaca tcacagaact gggccagttt atttttaatt ccttgaccag
    12841 ctggctcttc tgtacgaata accaacatat ttggttggat tcccaagcca cgcaattctt
    12901 tgacagagtg ttgggttggt ttggttttca tttcaccagc agccttgagg taaggaagca
    12961 aggttgtatg gatatacatg acattatccg cacccacatc tgccttcatc tgacgaagag
    13021 cctctaggaa tggcaaggac tcgatatctc ctactgttcc accaacctct gtgataatga
    13081 catcagagtc ggtcgttaga gcggcacgct tgattttttc tttcaaagca tctgtgatat
    13141 gaggaatgac ttgaacagtt gccccaaggt attctccacg gcgttcttta cgaagaactt
    13201 cactgtaaat tttcccagtt gtcacgttgg aatatttgtt gagattgata tcgatgaaac
    13261 gttcatagtg acccaagtcc aaatctgtct cagctccgtc atctgtcaca aaaacttccc
    13321 cgtgctggta aggactcatg gttcccggat caatattgat ataagggtca aacttttgaa
    13381 tggttacttt gagaccacga tttttcaaga gacggcctag actcgctgcc acaatccctt
    13441 tcccaatgga cgataccaca ccaccagtta caaaaatata tttcgtagac atagattcct
    13501 ctttctaaaa tgctcaaggt cttgttaact acgaggggat atagaaaaca agaccctact
    13561 aataagaata atctgggacg actgcaccag attcacaact aatactcttc gaaaatctct
    13621 tcaaaccgcg tcaacgtcgc cttgccgtag atatgtgttc ctgactttgt cagtcttatc
    13681 tacaacctca aaacagtgtt ttgagcagcc tacggctagt ttcctagctt gctctttgat
    13741 tttcattgag tataaaatac aagaagataa cttcttgaaa aaacaaaaat agctccctaa
    13801 gaactaggga gccccgacct ctaaaagagg tgcccaaaca atatgatacc taaaaatagg
    13861 ataattgtca atagctaact cttattcctc gctggtttca gcatcgtcat ctgaaaactc
    13921 gtcgtcgtct tcgttgagat ccacatcttc tcccaagtca tctggagcga tttcgttgat
    13981 ttctgcatca taagcttcca cttcattttt ttcatcatct ggattttcat catcgtatga
    14041 aagagctgga tctgcttcgt atgcatcttc gtcttctgga tcatctgcat tgtagtcaat
    14101 ggcatctgaa tcaccatcca taaaggcatt gacacgtttt ttcttagctt ttggtgctac
    14161 ttcatcgtcg tcattttctt caagagcgat gatttcttcg tcgatttcgt ccacaccata
    14221 ccatgaacga agaccccatt tgttgtcccc aagtgagatg aagctaccgt caaagttcaa
    14281 ctctgtgtag aacaaaggca aagcttcgcg gatatcgctg tttgatgttc caaggtagtt
    14341 ttgaatttcg tttacaagat cgctaaaatg catctcatga tcgcgaccac gaagttccaa
    14401 gatagcacgc gctacctcaa tcatagatag ttcacttttt tcttgcccag caaatacttc
    14461 taattccaaa gcgtttctcc tcatttatac tactatcgcc agagcgaaca gactctgacc
    14521 tcattttatc atttactctt tattttacga taattttgcg gaatagtcaa aggttaaggg
    14581 ggagaaagtg gcaggattag actaattcca atataaaact ccttcctttt tctgttgctc
    14641 cattttccac aaatccaagc gacttgaaac acctcctaga agcatgattg taggtgtaga
    14701 tttccttgac tctcaattct ttccatcctt ttactcgagc caattcaatc aaagcactta
    14761 gaatcttttt tccaagtcct cgatgttggt aagcggaatt cccaatcaca atggggagat
    14821 tatcctgaga tagtgtaata tccccaattg gaaaccattc tcccttctcc ttgacttcaa
    14881 tccaaaaaag ctcaccatgt cgatccaaat aggaatacat ggcttccaag gtcgcttgac
    14941 tgtaaggaag cttcacccca tctacgaggt aaaccaagtt cacatcctga taccaagcaa
    15001 aagcttcctc acaatgattg accttataat aaggaacaaa acacaatgca ctaccttttc
    15061 aacaaaagag ttgctgcttg attaaaacca tcacaccagt tataccattt tgcttcatac
    15121 ccatcttgag ctaggatacg atcttctaaa tcaaaaacag agtaaatctt tctttcctcg
    15181 caagcttgcg catagagatg atatagttca tcaccaccat ctctatccca ctcagcagaa
    15241 atcgtatccc gacctgccaa taaagcctga taagccctgt gatgcccatc tgtaatcagc
    15301 aaacaatctc caaaggcaag aatactgatt ggatcgactt ggtttgtttc tgccgactgg
    15361 taaagcatct gaatatcttg caacttcttt tctgataaat atagttgagt cggatgaaga
    15421 tctgctatat tgactttcat ttctttctcc tcaagggaat tcgatactca cttctgtttg
    15481 cctttaaatc gccattggaa gcggagcttg tcatagaagg gaaactcgat aaacaggact
    15541 cccaagccca cacagagact ggcaaggacg tctgatgggt aatgaactcc cagatagact
    15601 cttgatacca gcacactgac taggtagagg ccaaggacga tttgtacgat ttttctccag
    15661 actggatttt taattcgttg actgagaatg acaatcagag tgcctaccat caaggttaca
    15721 gccagagaat gcccacttgg gaaggaaaat cccttctcct ccacaagatg taagatagct
    15781 ggtcgtgggc gctggtagat atttttaaag gtcacgatta aaagacctgc caaagtcaga
    15841 tttcccagca tgaagaaact ttctatcttc catcgcttac gataaaagac aaaagctgta
    15901 atgacaaccc aagtgataat cactgggata tcaatcagac gtgtgagggc tcgaaaaaga
    15961 atagtcaaat aatctggtaa gtctcctcga atggcagtct gaatcgattg gtcaaaattg
    16021 accagcgttt cagggtaaaa tttgaccatg tagccaagaa taacgaaaag taaaagggca
    16081 aaactgccct tcattaaaaa tgtttgttta tctctcataa tgttttaagg ttggtttcaa
    16141 gagaacatat aacaaccaga atgaaacgga aaagataaca ccttcaatca agttaaaagg
    16201 taataccatg gtcattaggt agttggaaag tcccaaaatt tttccaatat caaagttagc
    16261 aaacttagcg tacaaaggaa cagcataaac atagttgaga accaacatgg ccaaggttaa
    16321 accaatagtt ccagctagag agcctagtag gaaacgaagg gttgtccgtt cctttttcca
    16381 aatcaaagca aatacgatga caaaaactcc caaagctacg atattcatcg gcaaaccaat
    16441 gtaagtattc actccttggc tgttaagaag caatttcaag agtgagcgaa gcaagagcac
    16501 tcctagagca gcaggcaaat ccatgaccac cagacccaca aggactggca agatactaaa
    16561 ttcgatcttg aggaaagatg ccgctggtaa aagcggaaag tcaaagtaca tcagcacaaa
    16621 tgagatggct gatagaattg caatggtcga aagtcgacgt gtgtttgtca taacaggttc
    16681 ctccaatttt ctataaaatc agaagaagtt ggaaaggatt cctctatcta ttctcacttt
    16741 ttatatccca aaagttccct cttactctat taaagaaaaa caaagcaagt ggttacaatc
    16801 cggctataaa tctatcaaaa cagacaaggc tattctttcg tcttctccca tccagactat
    16861 actgtcggtt gtggaatctc accacatcag cttgcgctca cggacttctt taaagagaag
    16921 gaaatagaga tttttctttt agactaggcg acaagctgta ggcataactt ctggttaggc
    16981 aaagcttgtc aacaaagtat aaaaggaaaa gatcatttcc tagttaaagt caccgccggt
    17041 cgggaatttc accctgccct gaagactctt ttatcataac aaaaaacgct tgcaagcgca
    17101 agcattttgt tcattttcat tttttatttc aatttatcca cttcataggt atggacgagc
    17161 tcaagacctg caaagttctg ctggcgaaga gcctcataga caatcatgca gacggtatta
    17221 gacacattga gactgcggac atgttcatca ttcatgggaa tacggagagc cttctcagga
    17281 tgttctcgca taaaatcttc aggtaagccc ttgtcttcac gtccaaagag aaaataatgg
    17341 tcctcgtcag tcgataaatc cacctcagaa tagacttttt ccgcgaattt cgaaatcaga
    17401 tagagttttc ccttcatctg agatatgaaa tcttccaaac tctcgtaaaa ataaatctct
    17461 agcttatccc agtaatccaa tccagcccgc ttcatcttgc ggtcatcaat aggaaagccc
    17521 ataggcttga tgatgtggag gggagaattg gtcgcagcgc aagtacgcgc gatattgccc
    17581 gtattttgtg gaatttgagg ttcaaataat acaatgtgat ttgtcatgac ttgcttcctt
    17641 tcaccattgc aaaaaaatag ccacactgcc cggagtcaag ctcagcaaac agcgtggtta
    17701 aggcatcgtt aacttacctc acaacaggtt tgaagtaaat cagcgaaact actttcttag
    17761 tataacactt tcagaatcat tgtcaataga aatgacttga ttttttcaat tttttcaagc
    17821 tatttccaag ggttgtaaaa tcgtccctga ttctgcaaga taagtagtaa actaactact
    17881 aaaaacaagg ttgccaagag caaggtaata tagtctcctt ttttcaaggc ctgataacta
    17941 taccatgtgc gttttttctc tttcccaaag cggcgaagct ccatggcagt cgcaatggta
    18001 tcaatgcgtt ctagcgagct aaaaatcaag ggcgtaataa tgagcagatt gcctttgatt
    18061 cgttgcataa gagaagcttt cttggataat tccatcccac gcgcctcctg agacatcttg
    18121 atagtaaaga attcttcctg caaatctgga atatagcgca aggtcaggct gacagaataa
    18181 gcaatcttat agggcacacc aatttgattt aaactggaag caaactgact aggatgggtt
    18241 gtcatcaaaa agataatagc cagaggaatg gtgcaaagat acttaatggc caaatttagc
    18301 agataaaaga gctcctggct ggttagagtg tagacaccga ttccctgcca aatcacactt
    18361 ctctctccat aaagtccaac cccatactcg ggagaaaaga gatagaccat caaaacgttt
    18421 aaaacggcaa atatcgtcgc aaaaacggct acaaaggaaa catctttaaa gcgaatttct
    18481 gataaataga ggagaaagac tgaaaagatg gcaatcagca agagcattct ggtatcatag
    18541 ctaatcatgg ccgccaatga taccagaatg aaaaagagaa gtttcccagc tcctgacaag
    18601 cgatgaatca cagtatctct atgctggtaa ccgattaatt tagcttgcat ccctctctcc
    18661 tttctttgta aaatgccgtt aaatccagtg gatccacatc tagtttctta gccaagttaa
    18721 agatggaggt ttcttttaga ttggctttta ctaacagctc aggatcgctc aacagactgg
    18781 ctggaacagt atcggcaatc aattctccat ccaccatgac aaggacccgg tctgaataat
    18841 ccagcatcaa ttgcatatca tgggtaatca tgacaatggt atgccctttt tgatgtaact
    18901 cttcgagaaa ttccataatc tcagtatagt tcttctgatc ttgacctgca gtcggttcat
    18961 ctaggagaat aatttcagct cctaagacca aaattgaagc aatggtgaca cgttttttct
    19021 gaccaaatga cagggcagaa ataggccaat tacggaattc ataaagtcca cagattttca
    19081 aggtttcata tactctcgtt tcaatttcct tctcatccac acctcgcaaa cggagcccta
    19141 gagccacctc atcaaaaatc atattggttg aaatcatttg attaggattt tgtagcacat
    19201 atcctactcg ttccgcccgc tctgcaacag aatcgccttt tatatcctgt ttttcccaaa
    19261 gatagcgtcc ttccgtctga ataaagctac ttatagcctt ggctagagtt gatttccctg
    19321 ctccattttt tccgacaata gcaatctttt cacccttttt aatatctaaa tgtagggatt
    19381 ttaaaatcgg tctatcatca taagaaaaag atacttcctc tagtctaaag agtgactgca
    19441 atgctggggt ttcttttgcc agttcattct gcaactgaac ctgacctttt gagatagaca
    19501 agttatccag attcgctaat tgttcttcct tgactaagtc cacacctaat tgacggagag
    19561 tcgttagata aaggggttct cgaattccat tttgagtcaa taaatcagtc gcaagcaact
    19621 ggtcagggct cccattaaaa aggatacgac catcgtttat caagacaatc cgatccacag
    19681 ggcgatgcag aacgtcctcc aaacggtgct cgataataag agtcgtcgtc ccctcttcct
    19741 tatgaatctg gtcaatcaat tcgataatat cctgacctga cttgggatct agattggcga
    19801 gtggctcatc aaacaagaga atcggacttt catcaatcaa gacaccagcc agactgactc
    19861 gctgcttttg tccacctgac aaatcctgag gacgctgatc cagtaaagga agaaggtcca
    19921 gcttttcagc ccatttataa acacgacctt tcatctcatc tagggctgtc acatcatttt
    19981 ccagagcaaa cgccaaatct tctgccacag acaagccaat aaactgccca tctgtatcct
    20041 gcaaaactgt gctaaccaga tgagacttat catagatgct catatcaaag gctacttgac
    20101 cctttatcaa aaattctcca tatgtctgac ccttgtaaat attgggaata atcccattca
    20161 aacactgacc caaggtagat ttacctgacc cagatggtcc aacaattaag actttctctc
    20221 ccttgtaaat ggtcaagtct atcccttgca aggtcggttc ttgttgtgtt tcataccgga
    20281 aagagaaatc cttccactca attatagctt ctttcatctt actctcttca ttcgcttctt
    20341 agacttctat tttatcataa atcaagccct tcttgcagtc tctcctctta aaatcttagc
    20401 gccaaaaaga ttcctatcct agcttacttg cctaactaat ctataaacat cgaaaaagac
    20461 tagttgccca gccttcccca tcattttata ctcttcgaaa atctcttcaa accacgtcag
    20521 cttcgccttg ccgtaggtat ggttactgac ttcgtcagtt tcatctacaa cctcaaaacc
    20581 atgttttgag caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
    20641 gtcctttttc aaacttcctg cacgagtttg ggttcctgca taggcaagta agagaagagt
    20701 tcctgcaata gctacagata caccattggc aattcccgca acaatccctt gtgcaaatac
    20761 tttttctgcc gcttcttgat aaatcacaac atctccaagt ggtgccaaga caccccaaac
    20821 aagggcattt gcaagtagtt gaatgagatt aaaaataaga atatctttcc agtcaaaaac
    20881 accattgatc acgcgaacgt actttctaaa aagtcccaca actaaaccaa agagtccgct
    20941 agcgataatc caagtccacc atagaccata accaacaaga gagtccttga ttgcatgacc
    21001 aatcaacccg acaagcaaac cgataatcgg tccaaaaata atagaaagta gcgcttgtac
    21061 cgcatactga agctggatgc ttgtatttgg aacaggggtt ggaatgttga tcatcccgat
    21121 gacgacaaag agggcagcgc caattccgac agcaacaact tgtttaattg taaatttgat
    21181 ttccatacta ttctcctatt ttatccttct attttcttta tttcaatggt ccaagatgaa
    21241 ccgacaccta cattataggc cttggcaaag gaaccttggt tgatagccaa acctaaacga
    21301 tagagagagt tgatgtaaag gatgggttgc ccaattctca catctgcaaa tgatttgcca
    21361 tagacaacct gattttgata gaccagcata tcagcatgat agatggtcac ttcaaaacga
    21421 tcaccaaatt ctggttccag cttgtaaaat tcttcccgtg tgatagaggt ccaaagcgaa
    21481 ccgaaacgca catccagaat atcaatggct cccttcacca gatgatcttc tatgatggtc
    21541 gctacgactg gaagctctac aatctgttcc acactgagct ctggccctac ttcctcaaaa
    21601 gtaatgtgac cactggccag tttagcacca gtataggcat agacatcacg accgtggaag
    21661 gtataagaat gctctgtgtt ttgacgccta ttggccacct cagaaatctc acgaatggct
    21721 acaatgccaa cgtgtttctt gataaaggaa agcgtcccat tatctggcgt gacaatgtat
    21781 tgattttttg cagtcttggc aactacactc ttacgtttcg aaccgacacc tggatcgaca
    21841 accgatacaa acgtcgttcc ctcaggccag taatccaccg tctgaaagag acgatagctc
    21901 ccctcaaaaa tattataagg cgtgatatcg tgcgtcaagt gatgtatttt taaggttgga
    21961 gactcttcta aagccactcc aatcatagcc gataccgcac catcaaccag accaaagtct
    22021 gattgtaata ccagtaaatt attattcatt ttatctcctt gtatatcctt tatcatacca
    22081 tatttcagag aaagtcgcta atagctattt caattggtta gggtatagtt ttaccttata
    22141 gcgaattttc actaaaaact cttgttatta gctagtaggt gcattttttc ttgaaaaagg
    22201 gtatgatagt tacatcatga aaaagtaggt tttattatga aaattatcct tgtcggaggg
    22261 ggaaaagttg gttttgccct ctgtcgctcc ttggttgcag aaaagcatga tgttttgctg
    22321 attgagcaag acgaagctgt tctcaatcat attgtcagtc gctttgatat cattggtatc
    22381 cttggtaacg gggccgattt tgccattctt gagcaagcca gcgtccaaga ttgtgatatc
    22441 tttatcgccc tgactgagca cgatgaagtc aacatgattg cagcagttct agccaagaaa
    22501 atgggagcta aagaaactat cgttcgggtg cggaaccctg aatattctaa ctcttatttc
    22561 aaggaaaaga atattctcgg tttttctctt atcgttaatc ctgagctctt ggctgcccgc
    22621 gctatcgcga atatcattga cttccccaac gccctgtctg tcgaacgctt tgctggtgga
    22681 cgcgttagcc tcatggaatt tgtcgtcaag tccaccagcg gtctttgcca aatgcccatt
    22741 tctgattttc gtaaaaaatt tggtaatgtc attgtctgtg cgatagagag ggatcatcaa
    22801 attatcattc caagcggtga catgactgta caggataaag atagaatctt tgtcactggt
    22861 aaccgtgtcg atatgatact cttccataat tattttaaat cacgcgccgt gaagagcctt
    22921 ctcatcgttg gggcaggtag aattgcctat tatctacttg gtattctcaa agatagtcgt
    22981 atcgatacaa aagtcattga aatcaatcct gaaatcgcca gcttctttag cgagaaattc
    23041 ccaaatctct acatcgttca aggagatgga accgcaaaag atatcctgct ggaagaaagt
    23101 gctcaacact atgatgccgt tgcgactcta acaggagtcg atgaggaaaa tctgattaca
    23161 tctatgttcc ttgacagggt aggtgtacag aaaaatatta ctaaggtcaa tcgtaccagt
    23221 ctcctcgaga ttatcaatgc gcctgatttt tcaagtatca tcacacctaa aagcatcgct
    23281 gtagatacga ttatgcactt tattcgtggt cgagttaatg cccagtattc agaccttcaa
    23341 gctatgcacc atctagccaa tggccaaatc gaaaccctgc aattccatat caaggaagcc
    23401 aataaaatga ctgccaaacc tctttctcaa ctgaaattga aaaaaggggt tcttattgca
    23461 gccattattc gaaagggcaa gactattttc ccaactgggg aggatatgtt ggaagttgga
    23521 gacaagctcc tagtaacaac cttgttgcca aacatcacca agatttatga cttgattgcg
    23581 aggtaagaaa tgaataaaag tatgattcgt tacctccttt caaagttact tttgattgaa
    23641 gctgttctcc tcttggttcc tgtggctatc gctgtctatt accgtgaatc gagccaagtc
    23701 tttacagccc tcttttcgac catagggatt ctcgtattgt taggcggttc agggagttta
    23761 cagaagccaa aaaatcaacg gatttatgcc aaggagggag tcttgatcgt tgccctctgt
    23821 tggatccttt ggtctttctt tggtggtctc ccctttgtct tttctgggca aatccctagc
    23881 gttattgatg ccttttttga aattagttct gggtttacaa ctactggagc aagtattttg
    23941 aacgacattt cggttctcag ccgttccctc ctcttctggc gaagttttac ccacttgatt
    24001 ggagggatgg gagtgcttgt ttttgcactt gctattatgg acaatgccaa aaatagtcac
    24061 ctagaagtaa tgaaggctga ggttcctggt cctgtctttg gtaaggttgt atccaaatta
    24121 aaaaacactg cccagatcct ctatctcctt tacatagccc tcttttccct ctttgtcatc
    24181 atctattatc tagccggtat gcctctctac gatagttttg tcattgctat ggggacagcg
    24241 ggaactggag gatttaccgt ctataacgat ggaattgccc actatggtag ctcactgatt
    24301 acctatctgg ttagtatagg agttttggtt tttggggtaa atttcaatct ctactactac
    24361 cttatgctcc gtcgggttaa ggccttcttt ggagatgaag agcttcgggc ttacttggtc
    24421 atcgtgctgg tttctacagg cttgattacc ctcaatactc tctacctcta cccaggattt
    24481 tccaaaagct ttgaaatggc cttcttccag gtttccaaca tcattacaac aactggtttt
    24541 ggatatggag atattaccaa ctggcccctc ttctcccagt ttatcctcct cttcctcatg
    24601 acaatcggtg gttctgctgg atcaactgca ggtggactca agattattcg aggcctcatc
    24661 ctttcaaaaa ttgccaaaaa tcaaattttg tccattctat ctccccaccg tgttttgact
    24721 ctccatgtga ataaaacggt gattgataag gatacccagc ataaaattct caagtacttt
    24781 gtcatctatg ctatgatttt gctatccctt atctttattg tcagcctaga tagcaatgat
    24841 tttctgatcg tgaccagcgc tgtctttagc tgtttcaata atatcgggcc tattctagga
    24901 accacttcta gtttctcaat ctttagtcct atctcaaaaa ttctcctctc ctttgcaatg
    24961 attgcaggcc gcttggagat ttacccaatc ctacttctct ttatgaagag aacttggtct
    25021 aagagataaa atacaaaatc cctcttttta caattgtgaa agagggattt ttatattaaa
    25081 aagggggaac gtttttaaat ccaagcctgt ctgtaagcaa agttcttact caaataaaag
    25141 atggaaaaac ttactacaca gcttggtaat gctccaatac aaattgtaag gctttacttg
    25201 gattctttgt taaatgaata tattccattc ctctggtagc aactatctga atacctaatc
    25261 tttctgcatc caccttcatc tctctataat aactccgaac ttgtggagcc agaataatta
    25321 aatcataaac acccataata tcataatgag ctccgtacgc tcctgaattc gcaatcactc
    25381 taacttctgc taattgagtg ccctcgttaa ttgcattggc taattgcgca cttgttccag
    25441 accctgcaca aagaaccagt actttcaact ccttactttt tattacatct atctcaccag
    25501 gcattatttc acttgtatcc tcctctaaaa taatatcatt tgagcttgca atatcttctt
    25561 tcaccagtaa ctgtctatca tacgctctac agaatggcaa ataaatcaat atgtcgacaa
    25621 ctaaaatcaa agataaaaat acaaaggaga taagttgaaa attcgttcca attaacaatc
    25681 ccaagggacc aggaaaggtc caaggtaact ggatataaaa tccattcatt ccaaagaaat
    25741 caataaagac ctttcctaga aatacattca ctggtggagt catcaaaaaa gggacaaaaa
    25801 gatagggatt caaaataaca ggcataccaa atagaagagg ttcatttacc gcaaataaaa
    25861 caggagtaat tgtagcttta cctaccgatt ttaattgttt agaccgcata aagaaaatca
    25921 aaataaatgg tacaacaaag gtagcccccg ttcctccaat agcagcgata taattcccga
    25981 aattaggtgt taaagaatga taagggaact gcccatttgc aagaagttga gcattctctt
    26041 ccatattgct cagttgcaaa gctgtaacag caggtaagac aatagatggt ccatgaattc
    26101 caacaaacca aagcaaagca cacataaacc aaatcaacat catagcagga tatgattctg
    26161 cccccttaaa aataggagtc aatagttgtt gaaatacttg ggcaaaagga acatctaaac
    26221 taaaccgaga tacaatatct aacaaaccac taataagtaa aacaaaagaa aaagggaaaa
    26281 tatctctaaa agcttgtgat atagccccag gaacttcctt aggtaaatga atagtaatgt
    26341 ctcgcttaat acagaatcgg taaacattta cagtaataaa ggcactgaca aacgaagtta
    26401 tcaatccttg agatcctaaa tagtttgtcg acaaacttgt agatcccgtc ttctcatcaa
    26461 ctacaagcgt tacagttaat accagataac tacatatggc tgccaacatt gcagaaatat
    26521 catttattac ctttccgtga ggcatttttc tgttaacatt tccaactaat gactttccaa
    26581 cagtccctga aacaataata cccaaaactc ccatggttaa catatacact tttctcatcc
    26641 agacaatagc tggactcggt aactctactc cgaaattttt aggaatcata ataataatca
    26701 tcaaaaagct tgaaaacata attaaaggca tagtagcaat gaatccatct ttaatagcca
    26761 tcatatagtt attagtagaa attttttcaa atttcccttg ttgcttttca atggcagcga
    26821 ctagcttacc cataaaactc ctcctataaa aaattcaacc tcatatttaa aacatattaa
    26881 acatcagtca aatcgctaac cttaattccg ttttagccct tttacccaaa gagcactttt
    26941 cttaatatat ctcttctgtg tttcataatc aacaaagaaa agaccatatc gcttattgta
    27001 gccattcgcc caagaaaatt gatcttgcaa agaccatata aaatagcctt gaatattgac
    27061 tcccctatct cgagcctcta aaactttgtg taaatgttgc tcaatataac ggattctttt
    27121 actgtcatca ataatatcat tctcgccctc tggcttaacc tctttaaggg ctgtaccatt
    27181 ttcagttaaa taaatgaccg gatgttgagg atattcttct ttgatacgaa gcaacatatc
    27241 aaataaccct tgaggataaa tattccaatc ccaatctgtt gtcggaatac caggcttttt
    27301 tacaaattca cctagagcat ttaatttaaa agaagactgt ccttttattc ctgttgaatt
    27361 aaattcttgt ctattttcac ctttgtattc acgaataaat tctgaacgat aataattcat
    27421 cccaaacatc gtattaagag gtgcagctct tttcataatt tctaaatcac catcttcaat
    27481 aataaagcta gaattattag cttccaatat ttgattcaag tgaaaaagcg tgtcatcact
    27541 gtagtagccc aaaaaagttc catctaatag aaatttatta ttataaacat cataccgttt
    27601 agctgctaaa atattttctt tttgcccatc aataggatag cctggcttta aagcatgaat
    27661 acaacctatc tttccctcaa tccctaattg atgaaattcg aggactgcaa gagcatgcgc
    27721 caacaacata ttatgattcg cttgaattgc ttcagataat tgaaaatgat gatttggagg
    27781 aaactgacct cctatatatt gacctgcagc aagagacatc agttcattga ttgtaaacca
    27841 atgcttgact tctgtaaatt cttggaaaca aaagcgagca tatcgtatga aacgatcaat
    27901 attctctcta ttcaaccaat cccctgtttc taacattttc tgaggcgaat caaaatgatg
    27961 taaagaaaca aacggaatca cattatgttt taagcaagac tgaaagactc tatggtaata
    28021 acgaacagct aatatattag gctccccatc tatatcagga aatatacgaa cccaagaaat
    28081 agataaacgc aaagcctgca aaccatgttc tgccgccaaa gctatatcct cttcgtaacg
    28141 ataataaaaa tcactagctg gatctggtaa gaacggactg ttttcttgca aataaacatc
    28201 ccacatattt gttcctttgc catctaccct agttgcaccc tctacttgat aagcagcggt
    28261 agcagctcct aataaaaact ccttcggtaa ggctttaacc tgtaaatttt ccatgactaa
    28321 tcctcattgc aaaccaatat gttcttcaat ctttcgaatt cgttcatatt catcaataaa
    28381 aaacttgacc tgatcataca atagcatcgt tgtcatcaaa gtatcttgac catgaatcat
    28441 gataaaactc acttcaaaat tatctccaga tgcctcctcc gctaataaat tagtctgttc
    28501 tcgatgggca gacactattg agtcgtttgc agactcaacc aattctcttg cctgttcaaa
    28561 atatccatct ctcgcaaacg ccaaagcatc catcaaatct gaccttgcat ctcctgcgta
    28621 agcgacaatt gtaaaaccaa gcatatttat ttcttctttt gatttcatct ttcttcctcc
    28681 tcaatcttga tccatctttt acacatcatt attaaaatga cttcgctacg atataaatag
    28741 aaagtcgacc ctaaatatct taaaaatcct taaatttcat aatatttagg atcaatcttc
    28801 tctgaatacc ttggttcatt ttctatactt atgatttata agtggaaacc agcgtaattt
    28861 tttgctactt caattacacg ataaacatcc aaattagatt ggaatagcag ttcgtgccca
    28921 cggatataat tcaacacatt tctccattca tcttgagctt gccttgtttt tccggttgct
    28981 tgaagatata aagccttcgc catcttaaca acatattcac gatgataact gagctgtttc
    29041 cattcatcct tttgactatt taataactta gaaatatttt cctcaataat tggcaaaaaa
    29101 ttatcagcta gattgtaagc tatataataa tgattcgcta aaacatcatt ttgacgactg
    29161 ccaattgcat taaaataatc acatgaggaa taactggata atttttctaa atattcaaca
    29221 acagactgcc aatttgaccc atacaaagca gaaaagtatt cttcaatcaa ttcttcataa
    29281 cttcttgtct tcttccagag catttccccc ataacataat taggaaaatt atgagggaat
    29341 ccggcacgta attcttgaca cgaaatgtaa ccgttcaaat gtaggttaga aagataagat
    29401 acatctctgt aaatggtttg actaattttc atatagccta aatcgccata atgagcacgc
    29461 cctaaaggat agtcatatac gaaactatct cctttaaatg ttttttgcca ctcaaaaaga
    29521 taagataaat tttcctcaag agaattcgga agtataattt tattacgcag ataaggttta
    29581 ggcgtaggta tggaattgtc aaaatctaca tctgcataac tcatttcaaa tgttcttgta
    29641 atcggtgcaa acatcatggt aaagcgttca ggattatcta atttttcttt ctgaggcgcc
    29701 catagcaact catggtaaag cagaaaacaa atctttgtat ctaatccctc actcgttaaa
    29761 gccctatcca attgattgag aatacgaata tactgatccg aaaccaattc ttgtctacag
    29821 ttttcgcatt cacaaatatt attacgagca tccgacaacc atacatgtaa gtagttaaca
    29881 tcaggtcttt tcttggcata atccttgata atttctacca tcttatccgc cacatctgga
    29941 tttgaaaaat ccagactggt taaaatcgga gccgtattaa ataattctcg tttcccgttt
    30001 atttcagcga catacggttt cttctcctct gaaatactaa gacctgattc ccagccaaat
    30061 tttgaagagt aacctaaaac ctcacctgtc catccatgac caacacgatg atgaataaga
    30121 cctctttttt gcaattcttt atccaaccta tcactcaatt cttgtactaa ttcatttgag
    30181 aatttttctt tatttaggta tggattaaac tcatgttcat accaacgttt caaaaaagag
    30241 taaggatttt caaactggat gaaaaaactg ttcatcccaa tcttaggtag ccaatcaatg
    30301 aaatctagta tattttcaaa tgaatccgct ccctctatac atactcccct atgatagtaa
    30361 ctggctgttt catctataga tagctgttta tctaaaaaat cttcaaatcg taactctgga
    30421 acaaagtcat gtctgcgccc tggtctagta tacacaaccc caaattcatg aaacattcgg
    30481 taaattccaa taagtaaacc tacaattgta ttagactcaa ttctcccctt acccttgtct
    30541 aatgagataa gaacatggtc ttttctgtcc tctttattga ctaatcctac aaaaatatcc
    30601 gcttccttct cctcgacaag ctctatgtta gtcttaaaga cccgattcat atagtaactt
    30661 aattcctcta aggcaaagct agaataagta tttttctgtt gatcaaatac tctgataacc
    30721 atcttatttc cctccaacag tagctttttc tttttcaaga ttgcgtttat ctgcaatttt
    30781 gaaaaatgga taataaattg ctacagaaac caaaatcaaa acaacttgta atagagctcc
    30841 tcgccaacta gctcctgtcg caaggaagcc tcctatgatc ggtggcattg tccacggaag
    30901 gattacacct gttgtatagg gtactaatcc tacagccatt gatacatagg taatcaaggc
    30961 attgattgta ggagtagcaa taaacggaat cagcataatc ggatttaaaa ctgttggaaa
    31021 cgtaaataga atagctgtat tgatattaaa aatagacggt ataatagcta gcttacctaa
    31081 tgttttattc gcacgactct tactaaatag gaagagacaa atcgcaagac caatagtcgc
    31141 tccaccgcca ccaataaata caaataaatc tttaaacggt aatgtaataa tgtgttggag
    31201 tgtttgtcct gcagccacag cttcttggtt ttctgtagta aattgtaacc aaactgggtc
    31261 tacaaaagca tttaaaactt gtcccccatt aactccacag aaccaaaaga atgagtttac
    31321 aataacacat agaatcatac ctggaagcgt tcctgcaatt aacttaagcg gtgttccaac
    31381 aattgcacct aggagtccgt tgagacctcc tgcaactcct gccgcttcaa gaccttttaa
    31441 gaccagagcc cacaaaacaa aagtagtaaa gccaggtaaa agagctgaaa atgatttact
    31501 taccacatct gggacaccac ttggcatttt tatcgtaatt ccgcgctgga taaacatacg
    31561 ataaatctct gctgtaacca atccaatagt aatcgccata aacaaagaag atgcattcag
    31621 gctagaaaat ggtattgcgc cgccaaataa ctgcttgacc tgctccccat ttttatcata
    31681 aaccatactc gaaaaacgag gtgccatcaa tacaaaactg gataaggcta tgatccctgc
    31741 cgacggacca tctgtaccat atccttccga caacctgtag gcaataccga aacaagcgac
    31801 caaggagata atcgctactg ttgactgatt catagttgtc aagatactta gcaatccaac
    31861 actattcagc caatttgtaa aagcctcttg aggccaactg attagaataa gaaataaaga
    31921 gccgactaaa atcaaaggca ttgccatcat aaatccttca cgaatagctt tcaaatgccg
    31981 ttggttgcca actttttcac caaacggagc gacttttgtt tctaaaaacg ctaaaatatt
    32041 gttcatcacc ggaactcctt tttttatttt ttataaatta aatataccac taacagaaag
    32101 cgttgtcaat atattttttg ttgtttttac aatatttttt ctttgtatag aataataatt
    32161 ttaattgatt ttttcttatg tttaatataa aataaaccaa aggaggaaac aaatgattac
    32221 aaaacaatca gcctttttac aaaatagagc cactatactg gagtttctat atcgaaatcc
    32281 agcaacatcc cgtacagata ttgttaatga aacaggactt actccagcaa caacgactaa
    32341 catcataaaa gagctaagcg aacagtccct catatacgaa actggtgatg aatttagcga
    32401 gttttccgga tctggaagac gtagaaaaac tatttctatc acagataata ttccgtatgt
    32461 tgttggaggt attgaaataa acgtcctagg tatctttctc agtctatgtg acttacaagg
    32521 gaaaactctt ttcgagacag aaattttgaa tgaagattat cctatttcag aaatcaattc
    32581 caccattacc aatatgataa aaacagctat agagtacgtc cctttggaaa caaaattact
    32641 tggatttggc ttatcaatac ctggacatta taacaaagac tccggaagta tcattacaaa
    32701 caaccccata tgggaatctt ttaatttatt aaatgtaatt aaaagattca attttccttt
    32761 tattgtaaaa aataatatcg attgtatggc tataggacaa taccttttta atccacacaa
    32821 tacccccgat aactttattt tcctacacgc tggattaggt atttacactt cctttttcac
    32881 aaaagaaaaa ataggagcct ctaaaaatcc ttatatcgga gaaattggac acaccattgt
    32941 cgaattgaat gggcaatatt gtgaatgcgg aaaaaaaggt tgtttacaaa catatatttc
    33001 ggatgcttgg ttaatcaaac acgcccaatt attatttaaa aattcccaac taactgtact
    33061 aaaaagcctt gtaaagactg aaaaagacat tcatttagac acccttttaa cggcttataa
    33121 tttaggcgac tccgctttac gtcaacaaat tgataaagga gtcaatttat tagccacttc
    33181 tattgcaaat ctcctcctca tcaatcctgc tgataaaatc tatatcaaca gtcaattgct
    33241 taattatcaa cctttcactc atgaagtcag ggataaaatc caagaccagc tccacttcgt
    33301 tccctttact cgtaatatag aaattgaaat tttaccttac aacaaacatc gtggaagtat
    33361 aggagcttgt gcattagcta tcgtcgcttt tttcatagaa catagcaatg tattacaaga
    33421 tattatttca ccttaatata ttagaaatct atagacctgt ttaaatcaac tataacctgt
    33481 agtagatatc tcgtatttag acaatatgaa aacaagacga cttccatata ggaaaccgcc
    33541 ttctcgctat gttgagtgat ttatattaaa ataacttttc ttctagctgc attttattat
    33601 tataaaaaca ttcatcataa cccccagaac ttaaataaca atttttattc aagatacata
    33661 ctcctagaat aaactttata tgaaattctc atttttgttt ttacaattct ccttagttaa
    33721 atcttgttta atatatgttt tacatatagt atttagcgcc acatagtact gaactctctc
    33781 caaaaacggt tattcctctt tgaatagggc gttatcacaa gaaaagcatc tccacgtttc
    33841 aacttcatat ggctcaaaaa caatcaattg atgctaaaac ctgtacctag atgtttcggt
    33901 tcataaaacc atgaaactgt aaaagtggat gaaattgata gcgatagtca aatcaagagg
    33961 catcataact ctaaaaagtc acaatatata agttcatcct cggaaaaata tcattctaat
    34021 tgttgaaatg cctacatgaa aagaaacgtc aaatgctcat gaaacaacga atacaggtat
    34081 caaaactatg acaaaacaag tccctaaatt tactaaagac actgctcaac tttacacctg
    34141 taaatggttg ttgtataata aagttacaaa gatgtacgac cacactgttg taaatcatag
    34201 tgttcgcgaa tatattactg atagcatttc tacaaataca attgaagaga ctggatagac
    34261 tttaaacgaa atatgtcagt gttttggcat tcctagcctt catatcattt aaagaattct
    34321 atagacaaaa tttttcccaa tacagacact cctaacaact gcttcatttt tctaccaaca
    34381 tatttaggaa caggataaga tacaagagga ttaatccata gatcagttct ataccaatct
    34441 aagacaaata agctaaaaaa acgattgata ataagcaaat agattccaaa ttttctctat
    34501 ctgctcattt taataaacaa tactagtgta actatccttc cagtcagaag cttgtcaaat
    34561 cacaccgaaa attcttctaa aatttatctc gttaggcaat caagcaaaaa ctcgacgata
    34621 gtacaaacat tatcatacag aattgacttc ctaaattata tactttagta aggttttcgt
    34681 ataagaaaaa agattcattt tacatttcta aacattcttt tctaagatga aaaacagaat
    34741 ttttcgattg tgatttaaag caacaagaag attttcagta tcatcctata gatacgagct
    34801 aattaagaaa aactacattt tcgaatataa actacaataa tataaactaa attttatagg
    34861 aggaagacaa tggattggta cgattatatg atacaggcat ccaaacaatc acaattcaac
    34921 gcaagccatt ggtttcgcta tttgcgaaaa gttatttttg aagactattc ttatttaaca
    34981 aaccaagatg tagaaaagtt gctagactcc aaagaactaa cccgttttca aaaaattagc
    35041 ttgaagtatg cctttcaaga gcatactcca actcataaat atgtgatttc attaaataaa
    35101 cctgctaagt taaccaatgt tcaaaaattg atggagaaat acaaacatgg ataaaatgaa
    35161 accggtcttc caagccctaa ataaggaatt aattcaggaa aatctgactt taacaattat
    35221 ctgtgtcgat ggttatgtct tagaatatca tggtttacgt gccacacaag atgttgatgc
    35281 tttttatgac caaaatcaga aaatcaatga aattattgct cgtgtaggaa aacagtttaa
    35341 tcttaacatc cacgaagagt tatggctcaa caatcatgtt gcaaagcaaa tatgaacaaa
    35401 caacctccct taagtttatg cgaatccttg tactcatttg agaatctgac cgttttagta
    35461 gtccctattg agtatgtgtt aggaatgaag atgatgagta tcagagagca ggatttgcaa
    35521 gatattggtg caattattaa atacaaaaac tttcattcac cattcgatac ctttaaatat
    35581 ttaaaagaca tgggatttga tactattgac ctctctgttc tattagaagg ttttagttat
    35641 gcttatggta tggattggtt agaaaaattt tttaaagaaa atcaagataa acttcgcgaa
    35701 ttttattaac agtatcaaac aagatgattg tcaattagcc agtcgtcttg ttttttatga
    35761 tgaaatgaaa taaaatctga acaaatcgct tagagaattc cagtcaattt ctagcgctgt
    35821 ttgagacgtt tcagtggact atagtaaaat gaaataagaa taggacaaat cgatcaggac
    35881 agtcaaatcg atttctaaga atgttttaga aataaaggtg tactattcta gtttcaatct
    35941 attatatttc agattcggtc cactattcct tcccaaaaac attgcatatt gcgtcaaagg
    36001 aattgctcac actatcccaa gcacaaaacc ctcagtcgat tgaccgaggg ttccttttta
    36061 ttattcaaga acttgattag ctcaatgcat ccaaggcgtc atccattgaa agaacttcgt
    36121 ggaagacacg ttgtgtcaat tcagtttttt gttctggagt gaggtattta gtgtttacac
    36181 agtatccaga gatacgtacg ataacgtctt cgcctgacat gatcttttcg taaacatcgt
    36241 tcaagtccat aacgttcaag ttaacgtgtt gtccaccgtt ttcgaagtaa ccatcaagga
    36301 ttgttaccaa gttatcaact tgttcatcac gagtcttacc aagagcgcga ggtgatactt
    36361 gtgtagtcaa tgagataccg tcagctgcat aactaaagtc aaggctagaa agtgagttca
    36421 agttttgcaa ccaaccacct ttagctttgt tagatgggtt agcacctggt gagaagaatt
    36481 caagtttaga caagttcaca gaaccatctt cgttgaggta tacacctttg tgaactggtg
    36541 agttaccagt ttgtttagag taagcaacgt tagatgtgat tgtcaaaagt gatactgtag
    36601 cttctgcgtc tttgtatagt ttgtggctac gtagacgagt tgtgtaagct tcgatcaacc
    36661 attctgccaa ttcgtttgaa cgtgggtcat cttcacccca gcgtgggtag tcaccgattg
    36721 tttcgtaatc gtagatgtag ccatcttcgt cacggattgg tttaactgta gcgtatttga
    36781 tagctgacaa tgtatcaaca gtgttagcaa atccacagat accgaatccc atgttggcac
    36841 gttgtttagt tggcaagaag gccatttgaa cagcttcgta gttgtaccta tcagtcatgt
    36901 agtggatgat gttcaaggca tctacgtaag tgtcagtcaa ccagtcaaga gatttttcaa
    36961 agttcgcttt aactgattcg aattcaagaa cttcgtcacg gattggttcg atatcaaata
    37021 ctttgtagtc tttgtgaaca tcgtcgtaac caccattcaa accagtaaga agggctttaa
    37081 gaacgtttac acgagcaccg aagtactgga tgttgtggcg ttgttcttca ttttctggat
    37141 caagtggaga cacacagcat gagatacagc tcatttcacc atatccgtct ttagccattg
    37201 ttgttacacc ttcgtattgg atagaagagt gtttgtggct catgtgcata cagtagcgac
    37261 ggaagttgta tggcaatttg tcagtccaaa gaactgtcaa gtttggttct ggtgagttac
    37321 cgatgttgtc aagagtgttc aagaaacggt agtccatctt agtaacacgg tgacgaccgt
    37381 cgttacccat accagccata gaagttgtga taaaggttgg gtcacctgag tacaattggt
    37441 cataagcttt tgtacgagca aatttaactg tacgaagttt cataacgaaa tcatcaacga
    37501 attcttggat ttctgattca gtaaatgtac cacgagcaag gtcacgttct gcaaagatgt
    37561 ccaatacgat tggtacacga cctagagatg tagcagcacc gttaatcaca cggcagacag
    37621 ccatgaaagc aatgttaacc cattggattg cttctttcac gttcatcgct ggtttgcgaa
    37681 catcaacccc gtaaaggtca cccaggcgaa caacttgttg caatgcttgg tattgaaggt
    37741 ttacttcttc acgaagacgg attgtttctt catcgatttc tttgattgca ttccagtcgt
    37801 ttactttttc ttgcatcaag tagtctgcac cgtaaagagc aagacgtgcg taaacaccga
    37861 tgatacgtcc gcgtgagtat gcatctggaa gaccagttac agtgtgtgca tgacgagcgc
    37921 gacgaatatt tgaagtgtag gcacggaaaa taccgtcgtt aactgttgtt acatatttag
    37981 tgaagatttc gtgaacagct gggtctggtt cgtatccatt ttcttttaaa gtagtttcag
    38041 ccatacggat accacctttt ggcatgaagt tcaatttgaa gagttcatca ttttggatac
    38101 caaagataac ttcattttct ttgtcgataa atccagcagg gatatcagcg atagatgttg
    38161 gacgagtgtc cattgggaaa cgagtttctt cgtagtgtgc tttagtttct tctacaattt
    38221 tcttgatgtg aagtgaacgc tctgttggtc ctgcaaggaa gctttcgtct ccatcataag
    38281 gtgtgtagtt agcttgtaca aagcgtgata cacttgcttt ttctttccaa tctacgcctt
    38341 tgaagccttc ccaagctttg tcaaaaatat cttgtgcttc aacaactgtc ttaacaacca
    38401 tattaatatc ctcttttttc tagtaacagt catctgttac attcataaga caagtatacc
    38461 ataaagtaac cgatttcaac aagtgcaaaa tccctatttt tacactttct tttctaaaac
    38521 agtctatatt ttatttcaaa ctgtattata tttttgaaaa aaataaagtc cttttttctt
    38581 tttttcagaa aaaagggtat aataaaagaa aataagcagt aacactcaat ggaaatcgaa
//
LOCUS       DAVEHY010000020        34864 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVEHY010000020 DAVEHY010000000
VERSION     DAVEHY010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.020"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(1..3678)
                     /gene="rpoC"
                     /locus_tag="VUZ44_001227"
     CDS             complement(1..3678)
                     /gene="rpoC"
                     /locus_tag="VUZ44_001227"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU0320143.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(3711..7322)
                     /gene="rpoB"
                     /locus_tag="VUZ44_001228"
     CDS             complement(3711..7322)
                     /gene="rpoB"
                     /locus_tag="VUZ44_001228"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU0320144.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDLIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            7738..7808
                     /locus_tag="VUZ44_001229"
     tRNA            7738..7808
                     /locus_tag="VUZ44_001229"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7770..7772,aa:Cys,seq:gca)
     gene            complement(8006..9337)
                     /locus_tag="VUZ44_001230"
     CDS             complement(8006..9337)
                     /locus_tag="VUZ44_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU0320145.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(9628..10452)
                     /gene="endA"
                     /locus_tag="VUZ44_001231"
     CDS             complement(9628..10452)
                     /gene="endA"
                     /locus_tag="VUZ44_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU0320146.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(10491..10679)
                     /locus_tag="VUZ44_001232"
     CDS             complement(10491..10679)
                     /locus_tag="VUZ44_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU0320147.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(10672..11955)
                     /gene="murA"
                     /locus_tag="VUZ44_001233"
     CDS             complement(10672..11955)
                     /gene="murA"
                     /locus_tag="VUZ44_001233"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU0320148.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(11979..12209)
                     /locus_tag="VUZ44_001234"
     CDS             complement(11979..12209)
                     /locus_tag="VUZ44_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU0320149.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(12267..13304)
                     /locus_tag="VUZ44_001235"
     CDS             complement(12267..13304)
                     /locus_tag="VUZ44_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU0320150.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(13288..13776)
                     /gene="coaD"
                     /locus_tag="VUZ44_001236"
     CDS             complement(13288..13776)
                     /gene="coaD"
                     /locus_tag="VUZ44_001236"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU0320151.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(13766..14305)
                     /gene="rsmD"
                     /locus_tag="VUZ44_001237"
     CDS             complement(13766..14305)
                     /gene="rsmD"
                     /locus_tag="VUZ44_001237"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU0320152.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(14370..15362)
                     /locus_tag="VUZ44_001238"
     CDS             complement(14370..15362)
                     /locus_tag="VUZ44_001238"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU0320153.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVLPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENVICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(15474..16157)
                     /locus_tag="VUZ44_001239"
     CDS             complement(15474..16157)
                     /locus_tag="VUZ44_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU0320154.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LLYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(16213..16953)
                     /locus_tag="VUZ44_001240"
     CDS             complement(16213..16953)
                     /locus_tag="VUZ44_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU0320155.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLFKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            16987..17265
                     /locus_tag="VUZ44_001241"
     CDS             16987..17265
                     /locus_tag="VUZ44_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU0320156.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYRLALKIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYPDFKIAN"
     gene            17343..18269
                     /gene="yidC"
                     /locus_tag="VUZ44_001242"
     CDS             17343..18269
                     /gene="yidC"
                     /locus_tag="VUZ44_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU0320157.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(18344..19138)
                     /gene="pflA"
                     /locus_tag="VUZ44_001243"
     CDS             complement(18344..19138)
                     /gene="pflA"
                     /locus_tag="VUZ44_001243"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU0320158.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(19264..20514)
                     /locus_tag="VUZ44_001244"
     CDS             complement(19264..20514)
                     /locus_tag="VUZ44_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU0320159.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(20581..21408)
                     /gene="purR"
                     /locus_tag="VUZ44_001245"
     CDS             complement(20581..21408)
                     /gene="purR"
                     /locus_tag="VUZ44_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU0320160.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(21675..22616)
                     /locus_tag="VUZ44_001246"
     CDS             complement(21675..22616)
                     /locus_tag="VUZ44_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU0320161.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(22606..23862)
                     /locus_tag="VUZ44_001247"
     CDS             complement(22606..23862)
                     /locus_tag="VUZ44_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU0320162.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(23864..24526)
                     /locus_tag="VUZ44_001248"
     CDS             complement(23864..24526)
                     /locus_tag="VUZ44_001248"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU0320163.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(24489..25145)
                     /locus_tag="VUZ44_001249"
     CDS             complement(24489..25145)
                     /locus_tag="VUZ44_001249"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU0320164.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(25156..26034)
                     /gene="rsgA"
                     /locus_tag="VUZ44_001250"
     CDS             complement(25156..26034)
                     /gene="rsgA"
                     /locus_tag="VUZ44_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU0320165.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(26036..26908)
                     /gene="rsmA"
                     /locus_tag="VUZ44_001251"
     CDS             complement(26036..26908)
                     /gene="rsmA"
                     /locus_tag="VUZ44_001251"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU0320166.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(27294..27440)
                     /locus_tag="VUZ44_001252"
     CDS             complement(27294..27440)
                     /locus_tag="VUZ44_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320167.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDKNMTNHLLLVQILVHGYLLDFA
                     SIEG"
     gene            complement(27433..28074)
                     /locus_tag="VUZ44_001253"
     CDS             complement(27433..28074)
                     /locus_tag="VUZ44_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320168.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(28076..30106)
                     /locus_tag="VUZ44_001254"
     CDS             complement(28076..30106)
                     /locus_tag="VUZ44_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU0320169.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWNQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(30183..30479)
                     /locus_tag="VUZ44_001255"
     CDS             complement(30183..30479)
                     /locus_tag="VUZ44_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU0320170.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(30799..31698)
                     /locus_tag="VUZ44_001256"
     CDS             complement(30799..31698)
                     /locus_tag="VUZ44_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0320171.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEECLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(31770..32330)
                     /gene="rnmV"
                     /locus_tag="VUZ44_001257"
     CDS             complement(31770..32330)
                     /gene="rnmV"
                     /locus_tag="VUZ44_001257"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU0320172.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(32330..33103)
                     /locus_tag="VUZ44_001258"
     CDS             complement(32330..33103)
                     /locus_tag="VUZ44_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU0320173.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQKQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(33408..34301)
                     /locus_tag="VUZ44_001259"
     CDS             complement(33408..34301)
                     /locus_tag="VUZ44_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU0320174.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSTPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(34585..34719)
                     /gene="rpmH"
                     /locus_tag="VUZ44_001260"
     CDS             complement(34585..34719)
                     /gene="rpmH"
                     /locus_tag="VUZ44_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU0320175.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT         9752 a         8186 c         6691 g        10235 t
ORIGIN      
        1 ttattctact gtttcttcca cagtttcaac ggcagtatcc acaactactt ctgttgtttc
       61 ttcatttcct tcttcctcta ctggaggatt aaggtattct tcttcgttga cagcatgtgg
      121 ttcaaggtta cggtaacggg ccataccagt accagctggg atgatcttac cgatgataac
      181 attttcttta agtccaagga gatggtcttt cttaccacgg atagctgcgt cagtaaggac
      241 acgagttgtt tcttggaagg aagctgctga caagaaactg tttgtttcaa gtgaggcttt
      301 ggtaattccc ataaggactg ggcgacctgt cgctggaact ccacctgcga taaggacatc
      361 tttgttggca tctgtaaagt cattgatatc catgagggta cccatgagaa gatctgtatc
      421 acctggatcc atgacacgga ctttacggat catttgacga accattacct cgatgtgttt
      481 gtcaccgatt tctacccctt ggctacggta aactttttgt acttcaccga gaaggtacgt
      541 ttcaactgac aagacatcac gaactgcaag gagacgtttt ggttggatag aaccttctgt
      601 cagagcagca ccacgcgcta cttggccccc aacttcgaca cgcatacgag ctgtaaatgg
      661 aacgacatat tcaccttcgc cagtttcacc cttaacaaag actttcttgg tacgagttga
      721 tgcatcttct tcgatagcag taacttgtcc tttaacctct gtgataaccg cttccccttt
      781 aggattacgg gcttcaaaga tttcttggac acgaggaaga ccctgagtga tatcggtatt
      841 tgaggcaacc ccacctgtgt ggaaggtacg cattgtaagc tgtgtaccag gttccccgat
      901 agattgggca gcaattgtac caactgcttc accaacttca accgcatcac cagtcgccaa
      961 gttgataccg taacagtgac ggcagacacc gtgacgagtg ttacatgtaa atacagaacg
     1021 gatagtcact tcttccacac cagcattgac aatttcacgc gccttgtctt ctgtaatcaa
     1081 ttcatttgga ccaataatca ctgcaccagt ttctggatgt ttaacagttt tcttagtgta
     1141 acgaccgttg agacgctctt cgagagactc gatcatctct tttccttctg cgatagaacg
     1201 gatcaagaga ccacggtcag ttccacagtc gtcctcacgg atgataacgt cttgggcaac
     1261 gtcgaccaaa cgacgagtca agtaacctga gtcggctgtc ttaagggccg tatcggtcat
     1321 acctttacga gcaccgtgag ttgagaagaa catttccaat accgacaaac cttcgcggaa
     1381 gtttgaaagg attggcaatt ccatgatacg tccattcgga gcagccatca gaccacgcat
     1441 accggcaagc tgtgagaagt ttgagatgtt accacgggct ccagagtcca tcatcataac
     1501 gattgggttc ttaggatctt ggttagcaat caagcgtttc tcaagttttt cacgggcagc
     1561 acgccattca gctgtaacag cattgtaacg ctcgtcgtct gtgatcatac cacgacggaa
     1621 ttgtttggtg atttgttcga cacgtttgtg tgattcttca atgatttcag ccttgtcatc
     1681 aacgactggg atatcggcaa tacccactgt caatcctgca agagttgagt ggtggtaacc
     1741 gaggttcttc atgcggtcaa gtagggcaga agtttctgtc gtacggaaac gtttgaagat
     1801 ttcagcgatg atatttccaa ggtttttctt cttgaatgga gggttgagct caagattgct
     1861 gatagcttcc ttgatatctc caccaagtgg caagaagtat ttagctggaa caccttctgt
     1921 caagttggca ttgtttggtt cttgcaagta tggtagcccc tctggcatga tatcgttgaa
     1981 gagaatttta ccaactgttg taagcaagac cttatgtctt tgctcttctg tccaaggctt
     2041 gttgaggctg tctgttgcga taccaacacg tgagtggagg tgaacataac cattgcggta
     2101 agccataacc gcttcgtcac ggtctttgaa gaccattcct tcaccttcgc gaccagcttc
     2161 ttccatggtc aagtagtagt tacccaaaac catgtcctga gatggagtaa ctaccggttt
     2221 cccatctttc gggttcaaga tgtgctcagc agctagcatg aggatacgag cttctgcttg
     2281 tgcttcttct gaaagtggta cgtggatggc catttggtcc ccgtcaaagt cagcattgta
     2341 ggcttcacag acaagtgggt gcaagcgaag agccttacca tcaatcaaga ctggctcgaa
     2401 ggcttggata cccaaacggt gaagggtcgg tgcgcggttc aaaagcactg ggtgttcttt
     2461 aatcacttct tcaaggatat cccagatacg ctcatctccg cgttccacca agcgtttagc
     2521 tgctttgacg ttttgcacga tatcacgggc aacgatttca cgcatgacaa atggtttaaa
     2581 gagttcaatc gccatttcac gcggcacacc acattggtac atcttaagag ttggaccaac
     2641 ggcgataact gaacgtcctg agaagtcaac acgtttaccg agcaagtttt gacggaagcg
     2701 tccttgttta cctttaagca tgtggctcaa tgatttcaat ggacggctac ctggtcctgt
     2761 gattggacga ccacgacgac cattgtcaat caaagcgtca actgcttctt gaagcatacg
     2821 cttctcattt tgaacgatga tacctggtgc atttaactca agcaaacgag ccaaacggtt
     2881 gttacggttg ataacacggc ggtaaaggtc attcaagtca gatgaggcaa aacggccacc
     2941 atccaactgc aacattggac gaagatctgg tgggataacc ggaaggatgt taagaatcat
     3001 ccattcaggt ttgtttccag acttgtaaaa ggcatccaaa acatccaaac gacggatggc
     3061 tttgacacgt ttttgtccag tagcagtttt caattcttct ttgagttcag caatttcttt
     3121 ttcaagatct acttgcttca aaaggtcttg gatggcttcc gcacccatct tagcaacaaa
     3181 tgaaccataa ccatattcac gcaagcgctc tcggtattcg cgctctgtca tgatagactt
     3241 gtgctcaagt ggtgtatcct taggatcaat caccacataa gccgcaaagt agataacttc
     3301 ctcgagggca cgagggctca tatcaagggt caagcccata cggcttggaa tccccttgaa
     3361 gtaccagatg tgagatacag gagctttcaa ttcgatatgt cccatacgct cacgacgaac
     3421 tttcgtacgc gttacttcaa ccccacagcg gtcacaaaca attcctctgt aacgaatgcg
     3481 tttgtactta ccacaagcac attcccagtc ttttgtagga ccaaagatca cttcatcaaa
     3541 gagtccttca cgttctggtt tcaaggtacg gtaattgatt gtttcaggtt ttttgacttc
     3601 tccataagac catgaacgga ctttacttgg agaagctagg gtgatttgca tacttttaaa
     3661 acgatttaca tcaaccacta tttcttccct ttctattcta agtgaactgc ttattcttgt
     3721 tcagcagctt cttctgttgc ttccgctttt gttgctttct cagcttcttc agcttcaaag
     3781 gctgctttag cctcttgggc tgctttttcg cgggcttttt caaggtcatc tacgtggatg
     3841 acatcttcgt ccattccttc atccaagtcg cgaagttcca cttcttggtc atcttcgtct
     3901 aggacacgca tgtcaagacc aagagattgc aattctttga caagaactcg gaaggattct
     3961 ggaacacctg gttttggaat tggtttgcct tttgtaatag cttcataggc tttcaaacgt
     4021 ccgttgatat cgtccgactt gtaagtcaag atttcttgaa ggacatttga cgcaccgtag
     4081 gcttcaagag cccaaacctc catctcaccg aaacgttgtc caccaaactg agctttacct
     4141 ccgagtggtt gttgggtaac agttgagtaa ggtccgactg aacgcgcatg caatttatcg
     4201 tcaaccatgt ggtggagttt gatcatgtac atgactccaa cagaaacacg gttatcaaat
     4261 ggttcacctg tacgtccatc gtaaaggatt gtcttggcat cgctatccat acctgcttct
     4321 ttaacagttg accaaagatc ttcagaactt gctccatcaa agactggtgt cgcaatgtga
     4381 ataccaagag tacgagctgc cataccaagg tgaagctcca taacctgacc gatattcata
     4441 cgtgatggca ccccaagtgg gttcaacatg atgtcgactg gagttccgtc tggaaggtaa
     4501 ggcatgtctt ctacaggaac gatacgagag acaacccctt tgtttccgtg acgtccggcc
     4561 attttatctc cgaccttaat cttacgtttt tgagcgatgt aaacacgaac caacatgtta
     4621 acacctgatt gcaactcatc tccatttaca cgtgtaaaga tcttaacatc acgaacgaca
     4681 ccatcggcac cgtgtggtac acgaagagaa gtatcacgca cttcacgaga cttgtctcca
     4741 aagatagcgt gcaagagacg ttcttcagct gaaagatctt tctcaccctt aggtgttact
     4801 ttacctacaa gaatatcacc ttctttaacc tcagcaccaa tacggataat ccccatttcg
     4861 tcaaggtctt tgagggcatc ttcaccaacg tttggaattt cgcgagtgat ttcttcaggc
     4921 ccaagctttg tatcgcgcgt ttctgattcg tattcttcaa ggtgaacaga tgtgtagaca
     4981 tcgtccttca ccaagcgttc gctcatgata acggcatcct cgaagttgta accttcccaa
     5041 gtcatgtagg caacgattgg gttttgtcca agcgccattt ctccattttc catagaaggt
     5101 ccgtcagcga ttaaatcgcc tttttcaacg acatcaccaa cttttacgag agtgcgttgg
     5161 ttgtaagcag tacctgagtt tgaacgacgg aatttttgga tgtggtaaac atccaatgat
     5221 ccatcttcac gacgaacttc taccttgtca gcatctgcgt aagtaacttt accatcatac
     5281 tgagcaatca cagccgcacc agaatcgtgg gctgcttggt attccatacc agtaccaacg
     5341 taaggtgcct gaggattaat caatggcaca gcctgacgtt gcatattggc tcccatgagg
     5401 gcacggttgg agtcatcgtt ttccaagaaa ggaatacatg ctgtcgcaac ggcaactacc
     5461 tgttttggtg aaacgtccat gtagtcaaca atattagctg gatactcttg gttgacccct
     5521 tggtgacgtc ccatgacaat cttctcagca aaggttccat cttcattcag acgagagtta
     5581 gcctgagcta cagtatattc atcttcttca tcagctgtca accaaacaat ttcgttcgtg
     5641 acaacacctg tttcacggtc aaccttacgg tatggtgttt gaacaaaacc atatttgttc
     5701 aagtgtccgt aagatgacaa gttattgatc aaaccgatgt taggtccttc aggtgtctcg
     5761 attggacaca tacgaccata gtgagtgtag tgcacgtcac gtacttcata tccggcacgg
     5821 tcacgagtca aaccaccagg tcctaaggct gacaaacggc gtttgtgaga caactcagaa
     5881 agcgggttgt gttggtccat gaactgtgac aactgtgatg aaccaaagaa ttctttaact
     5941 gcagctgtta caggacggat attgataatt tgttgtggtg tcaagacttc attgtcctga
     6001 acagacatac gttcacggac attacgttcc atacgagaaa gtcccaaacg tacttggttg
     6061 gcaagcaatt caccaaccgc acggatacga cgatttccaa ggtggtcgat atcatctaca
     6121 cggccaagtc cttcagccaa gttgaggaag tagctcatct cagcaaggat atctgcagga
     6181 gtcaccgtac gaaccttgtc atctgggtta gcattaccaa tgatcgttac gacgcgatct
     6241 ggatcagttg gagcaacaac cttgaatttt tgaagaacaa caggctcagt cacaacggct
     6301 gcatcgtttg ggatgtagac aatcttgttc aagtcgccat ccaaatggct ttcaatgctt
     6361 tcaatcacgc tacgagtcat aatcgtacca gcttctacca agatttctcc agtttcaggg
     6421 tctaccaatg gctctgcaat ggtttggttg agcaaacgtg ttttaacatt gagtttttta
     6481 ttgattttgt aacgaccaac tgctgccaag tcatagcgac gtgggtcaaa gaagcgagcc
     6541 acaagcaagc tacgtgagct ttcagctgtc ttaggctcac ctggacgaag gcgttcgtaa
     6601 atttctttca aggcttcgtc tgtacgagag tccattggat tcttgtggat atctttttca
     6661 acagtgttgc gaaccaattc gctgtcacca aagatatcaa agatttcatc atcacctgag
     6721 aaaccaagag cacgaaccaa ggttgtaaat ggaatcttac gagtacggtc gatacgagtg
     6781 taggtgatat cttttgagtc gctttcaagt tccaaccaag ctccacggtt agggataaca
     6841 gttgaaccat agcccacctt accatttttg tctactttgt cgttaaagta aacacctggt
     6901 gagcggacca actgagaaac gataatacgt tcaccaccat tgatgatgaa agtacccatt
     6961 tctgtcatga ttgggaaatc accaaagaaa acttcttggg tcttgatttc gcctgtttct
     7021 ttattgatca agcggaaggt tacaaaaatt ggtgctgagt agctagcatc gtggatacga
     7081 gcttcttcta gcgtgtattt tggttccttg atttcatatc caacaaattc caactccatt
     7141 gtgtctgtga agtttgaaat tggcaataca tcttcaaaca cttccttaag accgtggtct
     7201 aggaaagctt tgaatgagtc agtttgaatt tcaatcaaat ttggtaagtc aagaacttct
     7261 ttgattcttg aaaaactacg acgggtacga tgtttcccgt attgaacgtc atgtcctgcc
     7321 aagatgattc tcctttgtaa ataagttcca agccttgtca atcaggcttt tctaatcgtc
     7381 atatggttgt aaacccctta tcaccgtgtc ctcttgacga attttcagaa tctttaagcc
     7441 tctgttacaa atgctcataa tcttgaaaaa aagcacaaaa agagcagcta aatctgactt
     7501 tttcagaaga tttaactgct gtgagccttg tctggacaat atttcagaca aaacctacga
     7561 caaatgatta cccatattat accctattta gctagatttt tcaaggggtt tcagtaggtt
     7621 tttggtaaat tttttcccat agaaaacttg gcatcacatt cgaatcacgc tatggtacaa
     7681 aaaactgaaa aaactattga ctgaaaatca ttttcaaggt ataataataa acgttaaggc
     7741 ggtatagcca agtggtaagg cacggctctg caaaagcttg atcgtcggtt caaatccgtc
     7801 taccgccttc tataacttga tttatcaggt ttcaaatgaa cagaaagccc aatttgaagg
     7861 gcttttttta ttttccctcg aataaatacg tataacttta aaaacttttg gagcgagttt
     7921 gtggcagagt tctttccatg gcataattcc cttttgaaat caattgaaaa aagcttcgtc
     7981 acgcctggtg acaaaagcct ctagtttatt ctgtttcttc ttctatttcg acttctgtga
     8041 tttggacttt taccttggta acacgtccat tcttcacttt atcattggtt aagataaact
     8101 gtttgttttg gctgaccaat tcatagctga gtttctcagt cgttggaatg gttcccactc
     8161 ctgtcaaata ataaccagcg atggtatcaa cgtcatcact ttccagctca acatcaaagt
     8221 aattattgaa atcattgagg gtcatagttc cttgaacaat gtaggtatcc tcgccaatct
     8281 gatgaacatc tattgctgct ttgtccgttt catcatcaat ttcaccaaca atttcctcta
     8341 agaggtcttc caaagtcact aaaccagcca taccaccgta ttcatccagc aagattgcca
     8401 tttgtctttg ggtatttcgc agttctttta gcaagtcatc cacaaaaata gtttcaggta
     8461 caaaaagtgg atcttgtaaa attctcttcc aaacaatatt gtcaaaaccg tccacaaagc
     8521 ctgccttaag gagactcttg gtgtgaatga ttccaattac attgtcctta tccccatcat
     8581 aaaccgggat acgagaataa ttttgtttta aaatactttg gataatggct tgactatcat
     8641 cctgaatatc caccataaag gcatccgttc gaggaaccat aacctctcgt gccatcagtt
     8701 catcgagcga aaagacacct tgtagcatct caatctcatc agcatccaat gtttcttcac
     8761 tatttgtcag catataggca atttcatcac gggtcatttt ttcatccgca tcatcgaatg
     8821 acataggagt caaatggctc aagaaattgg tcgaggcagc taaaagccaa acaaaaggac
     8881 tgactagttt tccgatccca atgataaccg gcgctgtacg aattgccaag gcatccttta
     8941 gattaagagc gattctctta ggatataatt ccccaaaaac gatggaaata taggtcaaaa
     9001 atgccaagga tagaaaagtt gccacggctt gtgctgtttc gccattccca agccaagagg
     9061 caatcacacg tcctagagta tcagttaaac tcgcccctga taagattgta atcagggtga
     9121 ttcctacctg aatggttgat aaaaagtggt taggattttc tagtaccttc agcaggcgga
     9181 tgtagcgtct gtctccttct tccgcctttt gttcaactcg ggcacgatta agagaaacca
     9241 tggccatttc tgtggctgag aaaaaggcat ttaataccgt caagataaac aataaaacaa
     9301 attgtagcaa caaattctga ctacttgggt cttccatagt tcttctccta aaatagtatc
     9361 ttatccttta ttatatcaca aaatttaatc caatacatat tatttttttc ttagcgtaac
     9421 ttccatctct ctcccaaaac tggaagttag tctaagacgg atttccactg atttcacgcg
     9481 tttttctcat actaaaagct aggttgtggg aaactggaag ttagttttag aagttactat
     9541 tttttcttag tacctattct agccctgctt aaactagtaa aaagaactcc tacatccata
     9601 agtgacatag gagtttaggc ttatctttta ctgagttaca gttacttctc cagttcggta
     9661 atccagttga agtccctttt gaacattggg aactagaaca ttgaattcca attctccatc
     9721 cgaagacttg gcttcaatct gtgaagctga gggaactaaa tcctcgtttg aagcgtagta
     9781 aagggttaca cggtaacgga cacgcttgtt ttggtccaag gctttacgca ccttgctttc
     9841 atagtagttt tgaccagtcg aatactcggc ttgtgcctga tttgcccagg ctgtctgaac
     9901 agcaatgttt ttaggattgc ttgttgaggc atcaaaacca tccaaaccac cgattaaggc
     9961 atagcctaac aaatgacctc tatcgactgc atgggtataa gagcccttta gattcttgac
    10021 ctgatgccaa cctggaggag tccaagaagt tgaaccattc ccagtttctt tacgattctt
    10081 gtactgacga gtggccttag acaagagggc attagctacg gttggaacag tttccttgcc
    10141 cactgtcttt gttttattgt cagcgtaggg cttacttgaa accttggcat ctagatttgt
    10201 tttattacca ttgacgataa aagcacctga gccattccac tccagactcc cctttatttg
    10261 actcttgact gcgtctgtta agacactctc tgccaatgct tgactaggag cttcaggcgc
    10321 ttgttttttc tgactaagct tggttttagg actattagct gtcgactgca tctgcttgat
    10381 ataatagctc cctgtagaca aaagcaataa cactagcagt ccgattagtg tctgtcttgt
    10441 ttttttgttc atatttctcc ttatctttag aaaaaggctg gttctccagc ctaatttcct
    10501 gtaaatttat gaatcaattc ctgccatttt gctggagaca ggatagccca tggatcttga
    10561 cccttgccca agattccata acctaccatt aaaccgattc ctagagccag agtacctaaa
    10621 atcagtacta tgatgactaa aagtaaacgc ttgactacgt agcttgattt cttattcatc
    10681 ttcatcactt gcctcaatcc gctgaatctt agcacctagc tgcgccaact tctcatggaa
    10741 accgtagtaa cctctatcca agtgaaccaa tttaccgacc acagtttctc cctgtgctac
    10801 caaacctgtc aaaatcaaag ctgcactggc acgaaggtca gttgaaagaa cttctgctcc
    10861 ctgcaaaggc tgtccaccaa caatacgagc tgtatcacgg ataatctcag aatgcaagcc
    10921 catgcggcgc atctcttcta ggtgttggaa acgattttca aaaactgtct ccaccatggt
    10981 tgattcgcct tttgcaactg tcatcaaggc tgtaaattga gcctgcatat ctgttggaaa
    11041 tcctgggtgg ggcaaggttt tcacatgaac agcttttaga ttttccagtt gagaacgaac
    11101 acgaattcct tcgtcttctt caattacttc aacacccatt tcaagtaact tggcaatcaa
    11161 gggacggttg tgctcccaga cagcgtctcg aatcaagaca tcaccaccag tcatggcagc
    11221 agctaccata aaggttcctg cttcgatacg gtcctggact acattgtgag tcgtaccatg
    11281 aagtttctca acaccagtaa tggttatagt ctctgtacca gcacctttga ccttggctcc
    11341 catttcatta aggagaatgg ctaagtcaac aatctcaggc tcacgcgcag cattctcaat
    11401 cactgtcacc ccatcagcca gagtcgctgc catcatcaag ttctgcgttg caccaacact
    11461 tggaaagtcc atatagatat gagcaccatg caagcgttct gccttggctt cgatgtaacc
    11521 agctgtctga ctaatcttaa cccccatagc ttccagacct ttcaaatgaa gatcaatagg
    11581 acggctacca atcgtacaac cacctggcat ggataccttg gcatgaccca cacgggcaag
    11641 gattggccct aatacaacga tggaggcgcg catcttactg acatacttgt aaggggcttc
    11701 ctcagtgatg tcgccagtag catccacctt gacaagatga gcttcctcat caaagtcaac
    11761 cttggcattc aaaccaccaa ctacctgatt cataataaag acatccgaca aaatcggaac
    11821 attctgcaag acggtctttc cttcacttgc tagaatagtc gctgccaaca agggtaagac
    11881 tgcatttttt gctccctcga tcgtcacgct tcctaccaga cgattatcgc caccttgaac
    11941 cacaatttta tccatactcg tttcctttac tcttgatttt ataataatcc tctaagcgct
    12001 tcttgccaca aatgatacag gctaataaag aaagaactca ggatgtagcc tatgacaatg
    12061 ctaaaaaagg ctactaataa acgaactttt cttgtattat catctgtcac ttttaaaacc
    12121 ttctcccatc taacaagatc ctttaaaagg taaaaactca cataaataaa gaacatatga
    12181 ctacttagag tgaataataa ttgaaccatt tgactattat accatcttct ctgtttgtgc
    12241 gctagtttgg aaacttcact caaaaattag ggattgtttt tcaagtaatc aatcgcatct
    12301 tgtagggttt taacgggcac gattttcata tccgtcttga ttgttttagc cgcttctagg
    12361 gctgtttggt agttgttttt cgcgtccgga tgcgcctttt gttcttcttc gctaacaggg
    12421 ttatcaggag caaagaaaat agcagcacct gccctagccg aagctacaac cttcttatca
    12481 atacctccaa tgtctcccac attaccatcg cggtcaatgg tacctgtacc ggcaacaata
    12541 cgaccattac gaagatctgg gtgagctatt tgagtataga tagctagact aaacatgaga
    12601 ccagcacttg gaccgccaat accagctgtt gaaaagctaa ttgggacatt gctgattacc
    12661 tctgtacggt caatcaagcc gatcccaatt ccatttttgc cattttccaa ggtgatgatt
    12721 tttccttctg cagacttggt ttgcccatcc tcttcatagg tgaccttgac ggaatcccct
    12781 aatttttgag aactgacgta atcaatcaag tctttggaac tatcaaaggt ctgatcattg
    12841 actgctgtga ccgtatcaga gatattgaga atccctttaa aggttgaatt atccgtcaca
    12901 ttcaaaacat aaactccaaa gtacttgagt tcgatatcct taccagctgt ttttagtcct
    12961 tgatacttgg ccatattttg cgatgtttgc atgtagaatt gattgattcg cataaattca
    13021 acatcggaag aaccacctgt agtctcctga gcactacgaa tatctgtaaa aggtgtcaac
    13081 caagcataaa tcatatgagc taaagtggca tgttgaacac caaccgtaac gaattgatag
    13141 gcaccagctt ccttatcttc tgtgtcattt actttaagga cttggcgaat atcttccgaa
    13201 ccacctggaa cctctatata ataaggcaag ggcactacaa atgccaagaa agtcacaatc
    13261 aaggccgcaa tgacgtataa gggccatcta atcttttttt tcatttctta tttcctccaa
    13321 aatactctcg ggaacatagc aggcaatatc ctgaccaaac ttcaaaagct ctctaacgcc
    13381 tgatgaactg atatagagat gttcaggtcg actatgtaaa taaatagtct ctatatcaga
    13441 agacagctga tgattgtagt aatcaaaact ggcttcatat tgcaaatccg acgcattcct
    13501 caaaccacgc actagacaag tagcacccaa tctttttgca acatcgacca ccaattcatc
    13561 atgagaagcc acgacttcaa cattttccaa atgtcccaaa gccttttcta gcccccgttt
    13621 acgattttca agagggagaa atccttgttt gtggggatta aaaaaaatac ccacacaaag
    13681 cttatcaaaa agtctgctcg cccgttcaat gatatccaga tgcccatttg tcatcggatc
    13741 aaatgagcct gtgaataagc caatcttatc tgacatagac tgtcacctta ctaattccat
    13801 aaatcttttc cttccagata cccagacagg caatttcttc tggaagttca acggccttat
    13861 ccgtctcgca cacaaccata acatcttcag aaaaaagctc tctctcagcc attttttcaa
    13921 tatctgctac gatttgttcc ttggtatagg gagggtctaa gaaaacgagg tcaaattccc
    13981 cagatacctg ttccaatgcc ctttctgcat ccatcttgag gagttgaaat tttccaactt
    14041 ccttggtcat ctggatattt tcagccacga tggtctgagc cttacggtct cgctccacca
    14101 aaacagcact ggacatgcca cgcgatactg cttcgataga taaaccacca ctacctgcat
    14161 aaaggtccaa gactcgtccc acttcaaagt agggaccaat catgttaaaa atggctcccc
    14221 taaccttatc cgaagtaggt cttgttgtct tgccttctag tgtcttgagg ggacgtcccc
    14281 catagattcc tgatacgatt ttcatactgt ttattatacc aaattataga caaaaagaga
    14341 aagaaaaccg aaccttgcgg ttcgattctc tacaaaatat tttcgtaagt atcgcggact
    14401 tcttgaggcc aaacacttgt ttgcacttct ccgatgtgtc tcttgcgaag taggaacata
    14461 gccatacgag attgtccaat tcctccaccg attgtcaatg ggaataggcc attcaacaaa
    14521 gacttgtgcc attccaattc caagcggtct tcatcacctg taatttccac ctgacgtcta
    14581 agagtttctt catctacacg gattcccata gaagacaact caaaggctcc acctaaagac
    14641 tcattccaga caagaatatc accatttaga cccttgtagc cattctcaga ctcgcttgtc
    14701 cagtcatcat agtctggtgc acgtccatcg tgcggtttac catctggcaa ctcgccaccg
    14761 ataccaatca aaaagacggc tccaaattct ttacaaatca cattttcacg ttctttcggt
    14821 gtcaagtctg ggtagcgttc taccaattct tctgtatgga taaaggtgat ttgttttggc
    14881 aagatagact cgatgtcata gcgggcttca acagctagct cagtcagacg aatagcctta
    14941 taaatcttct caactgtttc ttttagataa acgatgttac gcttaccatt tgggagaacc
    15001 ttctcccagt cccactggtc aacataaaca gagtgggttg catccaagga atcctcatct
    15061 ggacgaaggg ctttcatgtg gacaaagaga ccctctcctt caccaaagcc aaaacgagcc
    15121 aaggtgtggc gtttccattt agcaagtgag tgcaccactt cataagtagc atcagggatt
    15181 tggagaacct tgaccgatac tggattttcc acaccagaca ggttgtcctg cattccgtca
    15241 ccgaccttac tcaagatagg accttgaact tcgacaactt ctagcttatc tttcaaatac
    15301 tgggtaaaag tgtttttgac aaaggaaatt tcttcttgtt gatggataaa acttttcttc
    15361 atagacaact cctcaaaaat ttaataaacg tattatacac ctatttccaa gaaaagaaaa
    15421 gagaaaattt aaaaaaaatc agtgtcactc aaaacactga tttcatagac cttttagtca
    15481 ttgcgaccaa agatacgtag aatacttagg aaaagattga taaaatcaag atagatgctg
    15541 agagccattg acaccaccca gcctgtcgct acacgacctt gtgattgttc ataggcgagg
    15601 cgaatctttt ggttatccca agcaatcaac cctgaaaaaa ccaaaaccat ggctacgcta
    15661 atcatataat caaagaagcc actagccaag aaaatattga ctaccatagc aatcagtaaa
    15721 ccaatgagag ctgccatcat tgctcgacca atcccactca agtctttctt ggtaaagata
    15781 ccaactgccg ccatgacaaa gaagagaagg gcgctcgata cgaaggcaga taaaactgta
    15841 cccggagtat agaaagccac cacaaaacta agggtaaagc cgtttaaaac ggagtaaagt
    15901 aaaaatactg gaagagcagc tggactattt cttgaagcca tgctactggc aacgaaaacc
    15961 aaagccaact ccgcaaaagt agcaatggtc aaccagagac gcccctgcat caaaaagtaa
    16021 agcaactgag actgaaagac cgtcaacata aggcctgata ccaaagcaga tagtccgatt
    16081 cccagaccaa caaaggcata aaccttagcg taaaattgat tgagacctgc acggtcatgt
    16141 ataatagtgt gattcatcct tttctccttt tctgtgaaca tctttccttg attataacaa
    16201 aaaaagttaa aattagctta aatggaagat taaaataccg gctgcaaccg caacattcaa
    16261 actctcggcc tgccccttca tgctaatatg gaccaactgg tctgcacttt cagccataag
    16321 gggactaatt ccttgaccct catttcccat aactagtaca aaattttcta tagaaggcag
    16381 ttctctgtaa tcaacagaat ctttaaatag ggttgttgct agcactggga tagctacctt
    16441 tttagtttcg tcaagaagcg cttgactagt catccggtaa atgggcagat ggaaatgact
    16501 accttgcatg gaacgtaggg ttttgagact gtagatgtct gccgacttat ctgaaacaat
    16561 cactcctgta aaacctgctg catccgcagt tcgaatgata gttcctacat taccaggatc
    16621 ttgcacatct tccaaaaaca agaacttgcc ctgactcaaa tcagcttgtc ccacttcttc
    16681 tttttgaacc accgccacaa ttccctgtgg agtctgagaa tccgccaaat ctagcaaaat
    16741 atcctctgaa atccagacag tttgcggaaa agcagctaac tgatttcggt aattttctag
    16801 ggcaaagatt ttctcaatcg tcactccagc ttggacagct tcttcaaaca agtgccagcc
    16861 ttcaatcaaa taggctgact tgcggtattt tttttggtgt aatttcttgg cattttttac
    16921 cacagaattg gcttttgagg ttataatagt catagaaata ttataacaca atcaaagggg
    16981 tttggtatgc aaaaggttag aatgattgcc caaggtaggg tacagggagt cggatttcgt
    17041 tggggtgttt atagactggc ccttaaaatt ggtggcatca caggtcgggt atggaataat
    17101 gacgatggaa cagtggaaat cttagcccaa gcagactcat ctgctatcat ggcaaaattt
    17161 atccaagaaa tccgaaaagg accgacacct ttttcaaaag tcagttactt agatgtcaaa
    17221 ctgagcaact ttcctcccta tcctgacttt aaaatcgcaa attaggtctc tagaactatt
    17281 gtatattttg taaaaaaaca gtagaataga aaggtataat ttttaaagaa ggaataaaaa
    17341 cagtgaaatc tattaaacgt tttgcactct cggctatggg agtggctatg ttgcttgtct
    17401 tgactggctg tgtcaatgtc gataaaacca caggtcagcc aacaggattt atttggaata
    17461 cgatcggagc gcctatggct gaagccatca agtacttcgc tactgataaa ggtctaggct
    17521 ttggtgtcgc tatcattatc gtaaccatta tcgtacgctt gattatctta ccacttggta
    17581 tctaccaatc atggaaggca acgcttcact ctgaaaagat gaacgctctc aagcatgtcc
    17641 ttgagccaca ccaaacacgt ctcaaagaag caactactca agaagaaaaa ctcgaagccc
    17701 aacaagccct ctttgccgct caaaaagagc acggcatcag catgtttggt ggtgtaggat
    17761 gtttccctat cctccttcaa atgcctttct tctctgctat ctactttgct gcccaacata
    17821 ctgaaggggt tgctcaagca agctacctag gcattcctct aggttctcca agtatgattt
    17881 tggttgcctg tgctggtgtc ctttactatc ttcaatcgct cctttcactt cacggagtag
    17941 aagatgaaat gcaaagagaa caaatcaaga aaatgattta catgagccca ctcatgatcg
    18001 tcgtcttctc cctcttctca ccagctagtg tcacacttta ctgggttgtc ggtggtttca
    18061 tgatgattct ccaacagttt atcgtcaact atatcgttcg tccaaaactt cgcaaaaaag
    18121 tccgtgaaga actagccaag aacccaccaa aagcaagtgc tttctctaaa ccaagtggac
    18181 gaaaagacgt tacccctgaa caaccaactg ctatcacaag caagaaaaaa cacaaaaatc
    18241 gcaacgctgg aaaacaacgt tcgagataag aagaaaaagg cttagctgat ttgctaagtc
    18301 tttttgcaaa tcaaaagccc gatgtttcca tcaggcttct tttctatcca tgtacacgtt
    18361 tcatataatc ttgataactt tcggtatcca tgagtttttt agcgttcttg acgcgatctg
    18421 ctgttggtgg tttgactcct tcgagggaat atggaattcc aagttcacgc cacttgaact
    18481 cacccatggt gtgataaggt agaatttcaa acttatcaac atttttgagg gtcttgacga
    18541 acttaccaag ttcaatcaag tcatcatctc tgtctgtcaa tcctggaact agcacgtggc
    18601 gaatccagac aggttttcca atatctgata gatactgggc acaagccaag atatttttat
    18661 tagtttgtct agtgacaatc ttgtgctgtt cttcgttgat ttccttgata tccaaaagaa
    18721 ccaagtcagt gacagccatg agtttgtcaa acttctcaag gtaacgtggt ttattacgga
    18781 aaggaagagc acaggtatcc aaggtacagt ggattccttg ttccttagcc ttggtgaaga
    18841 gagcaatcag gaaatcaatc tgcaagagag cttctcctcc actgactgta atcccaccct
    18901 tatttcccca gaaaccacgg tagcgcaagg cctctgtcaa gacatcatct accgtccgtt
    18961 cacgtgactt attggactcc atagcccaag tgtctgggtt gtggcaatac tggcaacgca
    19021 tgtgacagcc ctgcaaaaag acaataaagc gaataccagg cccatctact gacccaaagc
    19081 tttctgtcga atgcaccatt cctgtcactt gtccataatc aattgtttct tcagacatat
    19141 cgttaccttc cttgaaaacg ttttatagtt ttattatatc acgacttgaa ggaaaaacaa
    19201 gatttttgcc tattttttag aaagcaatct gtttttcaat ttcattttca atctattatc
    19261 agattattct tcaaaatcga agccatataa ggttgcaaaa tagtcctcag ggcgctctgc
    19321 acggcggatt tgacgggctt taccttcttc ggtatagagg atttccgcag aacgtaattt
    19381 ggcattatac tggtagccca ttgaaaatcc gtgggcacct gtatcatgaa ttaccagcaa
    19441 atcaccgatt tctgtatgag gcagttcgcg attgactgca aatttatcat tgttttcaca
    19501 gagtgaacca accacatcta ccgcttcagc tggtccatct ggatgggtca cgttgctaat
    19561 atgatggtaa gctccgtaca tagctggacg catgaggttg actgctgagg catccacacc
    19621 tagataggta cggtaggttt ccttcttatg agtcactctt gtgactagag caccgtgagg
    19681 tgccagcata aaacgaccca attcggtgaa aatcttgacc tgaccaagac ctgctgacgt
    19741 aagaacttct tcatacacct tacgaactcc ctcaccaatc aaggcgatat cgttcggctc
    19801 ctggtctgga cgataattaa caccaatacc gccagaaaga ttgataaagt ctagccaaat
    19861 gcccaacttt tccttgattt caacagccag ttcaaagagc tgacgagcca actctggata
    19921 atagagatgg gtcacggtat tggacgctag gaaggagtga atcccaaaag tcttggctcc
    19981 tttttccttc aagatagcaa aggcttcaaa gagctggtcc ttggtcatgc caaacttagc
    20041 ctccccagga ttgtccataa tgtctgtccc cagttcaaaa acgcctccag gattataacg
    20101 acaagagatg atttctggaa tgcctgctac tctctccaga tgttcaatat cttcaaaggc
    20161 atccaagtta atggtcgcac ccaattcacg tgcataggcg tattccttgt ctggcgtgtt
    20221 gttggaagag aacataatct cagaacccag aaagtccagt ttatggctca tcaaaagctc
    20281 tacataacta gagcagtcca caccacaacc ttcttcttgg agaattttca aaatagctgg
    20341 agttggagta gccttaactg caaaatattc cttaaagccc ttgttccacg aaaaagcttg
    20401 gttgacggct cttgccttct cacgaatccc cttctcatca tacaagtgaa agggagtcgg
    20461 gaactcggca acaatcgctt ctaactcttc tctattgata aatggtgttt tcataagctt
    20521 ccttctattc tgtttgcaaa gaaaggctgg gacaatcgtt ccaaccttta gttctatctc
    20581 ttatttatct tcgtcaaaga tattgccaac ctcaacatcg atggcttggt tcttgacatc
    20641 aatattagtt accttcaaga gtgacttgta gtcaaactgc ttttcacgtt cttcttgggc
    20701 attgtccgca aagaccgcta cacctgccag ttctgagtcg aactcgcgca agagactaat
    20761 cataccgttg accgttccgc cacctttcaa gaagtcatcc acaatcaaga cacggctacc
    20821 tgccttaaga ctacgttttg aaaggaacat tttctcgata cggtcaccac ttgaacctga
    20881 aacatagttg acgctaacag ttgaaccttc ggtaattttc aggtcacggc gcacaatgac
    20941 aaaagagaca ttgaggacat tggcaactgc atttgcaagt ggcacaccct tagttgctac
    21001 ggtcataacc gcgtcaattt tttggtccat aaagcttttg gcaataatac gaccaatatt
    21061 tttcaagatg gctggtgtgc taagcaaatc agacagatag atataaccac ctggcaagat
    21121 acggtcactt tctgacaact tggtacgcaa gtcttcaacc atttccttag catcctgact
    21181 cgaaatagac ggtgtgaaga tgacacctcc gccagcccca gtcactgtct ggatatgacc
    21241 gatttcaatt tcctcaaagg cgcgtttgat aatgacgata tcttctgaga tggatgattt
    21301 agcagactca tacttttcag caaaagtatt gagactagtt agtttataag gattattaat
    21361 caaatagttg gaaatgacaa ccatccgatc acttcttctt aatttcattt ctatttccta
    21421 ttccattttt attcaaaaaa tcaaaaagca aactagaaag ctggtcgctg gtggttcaaa
    21481 acactgcttt gagattgtcg atagaactga caaaccctgt aatatacctg catatataca
    21541 tacgacaagg cgatactacc ctagtttgaa gagattttcg aagagtattc atttttgtct
    21601 tttacttatt ataccatatt cacataaaaa aacgaacatt cttatcctaa aaaatgctca
    21661 tttttcttaa attatcaatc taaatctggt ttatagaagg aacgattatc catagcgaag
    21721 attttattgg tcatctctcc tttatccacc aaagccagag ctgttgacat catcatcatg
    21781 cttgcatcca gattgtcaat catatggata atctctgcct ccataatacg tggacggact
    21841 ggacttccat attcaagcaa gccgtggtga ctgaggatga catgacgaag caaaacgact
    21901 tcttccttgg tatcatcgat gccgagttcc ataactgtct tggtaatttc gctatcaatg
    21961 agagcgatat gtccaagaag attacctcgc actgtgtact ctgtctggtc tggccccgtc
    22021 aactcgataa ccttagctaa gtcatgcagc ataatccccg catagagcag gctcttattg
    22081 agctgaggat aaacttcgct aatagcgtct gccaaacgca ccatggtcgc cgtatgatag
    22141 gccaagcccg tttcaaaggc atggtggttg gtcttggcag ctggatagga gtagaattcc
    22201 ttatcatact tggtgtagag atttcggaca atccgttgcc agacaggatt ttcaattttg
    22261 aaaatcattt gcgacatgta gtcacgaatt tccttgacat caactggtga cttgaccttg
    22321 aaatcagctg ggtcattggg ttcaccagct tgaggcaggc ggagagtaat ttgattgact
    22381 tgaggggtat tgttataaac ttctcggcgt cctttcatgt ggacaacctt acctgcggta
    22441 aaggcctcaa tgttatgagg ttgggcatcc cagagcttcc catcaatctc gccactatca
    22501 tcttggaagg taaaggctag gtagtttttc ccagctcgag tttgcctcag gtcagctgat
    22561 ttgattaggt aaaagccttc aaacaactca tcttttttca tgtgactaat cttcatattc
    22621 ttcctcattt tcttgaaaat ggagtagatc aagcgcaggc tcaccttctg acaactcaat
    22681 gtgacggagc gtccgctcga tagctatggt acgacggttt aataattcat caatattgcc
    22741 agaggcatgt tggagatgtt tttgtgcctt gaccagaata ccaccaaact tgccaaactc
    22801 ggtcttgaca ctggcaagag tcttgctgat atggtcggca ctcttttgga tattaagggt
    22861 cttgaaacca actgataggg agttaagaag ggctgatagg gtacttggtc ctgcaacgat
    22921 aatctgttct tcccgtctca aatcatcaaa gaagaccgga ttgcgcacaa tctctgaata
    22981 aagaccttct gtcggaacaa acaagattcc aaaattggtt gtccgaggcg gtgctatgta
    23041 cttgctcttg atatccttgg caaagcgctt gacgcttgct aggagtgact tacgacagcg
    23101 ttcaatctca tccttgtcac ctgtctcata ggcttcttcc aagcggtaat aatctgccag
    23161 tggaaactta gagtcaattg gcagatagac gtattcttgg tcgccttgtc cgggtaactt
    23221 gatggcatac tccactcgtt cactagagtt ttcaaccgtt gcgtattctc gttcgtactg
    23281 ggcaggtgtc atgatgtctt caataatttg ccccagttgc aattctccca gaatccctcg
    23341 cgtcttggtt ccagagagaa ccttgttaag agctccgaca tcacgggcaa ctgtctgcat
    23401 ttctccaaga ccacgattga cagactccag ttgtttagaa actgtctcaa aggaagcctg
    23461 taagcgtgtc tgcaaggtct tttctagttt ttcctcgacc gtctggcgca tttgttccaa
    23521 acgttgctca tttgattcct gcaaggcttg gagacgttgg tctgtcttgt ctctagtttg
    23581 gaggagatta tctgtcattt cttgacggac ttgggtcaga ccttggtgca attcaatccg
    23641 cacttcttgc aaacggtcgc tgacaaccac ttccaaatct ttttggtcta actggctggc
    23701 ttgtctggct tggtcaaagc ggtaatccaa ctggtctgac aaatgatctg cctgatcctc
    23761 caagctctta cttaagtgtt tctcctgcct atcctgtctt tgccaaatca gaaagagacc
    23821 agctaggttg gcaattaata atagaataag taaactttcc atcctacctc ctgtccttgc
    23881 tatgcagtac gaccacataa ccatctgggc aagtcaccga cacttcccta tctatatatt
    23941 cgttagaagc gtacactttt ttaaagaaaa aattctcctc tgtcaactca tacttagctc
    24001 caagaatagt cagctggcta tcccgaactg gcataaaggc tagatagtcg tagtctgaac
    24061 gaggttctag ctgactggtc ccttctgaac aataggcaat caaattttgc ccatcctcaa
    24121 tttctatttg acgcatatag ggtgccaact taggattgct aggtagaaag acattggcca
    24181 acatatggtc aatacggcca cccaaggcac cgaaaatagt gacctcagcc tgaggatttt
    24241 gttcaaagat ggttaagaga gccaattcca gatctgtatc atccttttct ggtcgggctt
    24301 ggacaaaatg ctgggcacgt ttttgaatca cctgtcgctc ttcttccgtc acagaatcaa
    24361 aatccccaac tgctagagca agaagcaagt cttcttccaa gacccagagc gagcctcgat
    24421 ccaccccaac aaaagcatca aaatctgtcc gataatgacc gcggtctccg cctgcaaaaa
    24481 cggcaaccct agtccagttg ttttctgaga gtttgtactc gctcattgac atctccctta
    24541 aagacatagg aacctgctac aaaaacggtc gcaccagctt ctttagcttg ggcaatagtt
    24601 tggtcatcaa tcccaccatc cacttcgatt tcaaagttca aacctttttc ctcacgaaga
    24661 gcaaccaact cacgaacctt atccatggtt tctggcagaa aggcttgccc accaaaacct
    24721 ggattaaccg tcatgactaa aacttggtca actagatgaa ggacgtgctt gatggcttca
    24781 actgatgtgc caggattgat aacgactgaa ggcttaactc cgagtgaacg aattttttgg
    24841 agggcgccat gaatatgagg cgttgcttct acatggatac tgatgatgtc tgcacctgca
    24901 cgcgcaaaat cttccagatg atgctcaggg tttgacacca tcaagtggca atcgaaaacc
    24961 atcttactat gaggacgaag gctctcgacc acacctgcac caaaactgat ttgcggtaca
    25021 aaatgactgt ccatgatatc gatatgggca tattctgccc cagttgcttc tagacgtttg
    25081 atttcacgtt caaagttggc ataatctgct gccagaattg acggagcaat cttgtattga
    25141 gacataggtt tctccttatt ttggaatttt tttgctgact tttttatagg tttctctacg
    25201 attttcaatt tcactaagga attgcaggta attgtcaaaa cggaaggttg caataacacc
    25261 ctcttcaaca gctggtttga cggcacaaga cggctcatgg gtatgggtac aagtacggaa
    25321 cttacaatct cggctaacag tagcaatctc tgggaaagcc tgattgaggt cttcagccct
    25381 tgatacttca tagtccaagg atgaaaatcc tggtgtatct gcgattttac ccccgttgag
    25441 attgtaaaaa ctaacagctc gagtggtatg gcgaccgcga cctagactgt ctgaaatttc
    25501 tcccgtttca agattgaggt ctggtgcgat tttattgaga agagttgact tcccaacacc
    25561 tgtctgcccc ataaagaccg taaccttgcc tgttaacaaa gacaggagtt cctctttact
    25621 ggtcacaaag tcatagccga tgtcaccata ggtctgctgg taaaaatcca gttctcccct
    25681 atcttccaac aaatccattt tggaaatata gacaatggga tggatgccct tgtgctccaa
    25741 aagaaccaag aaacgatcca gcaaattgct gttaaaatca ggttccttga cggacatgat
    25801 tactacagct tgatcgatat tgacaatagg cggacgaacc agactgtttt tccgttcgtg
    25861 aattttgagg atatagcctt ctgaattttc ctcggcagag aaatctaccc agtccccaac
    25921 ataaggggta tggccttttt tacggaaatt cccacgcgcg cgtgtttgat aaacctggcc
    25981 atcactctcc acatagtaga aacctgccaa ggctttaatg atttgtccct gcatcttaga
    26041 gtccttgccc tttaagtgcg tctgctagac cggcaaattc tgccaagctg agagcttccc
    26101 cacgcacact tggtgacaag cctgcctggt ccaaagcctt ggtcagcttg tccttgacct
    26161 cttcagtctt accaaagtaa cctgtcaagt tattccacaa ggtcttgcgg cgatgggtaa
    26221 aactagcctt ggaaacctta aagaaaaagt tctcatcttc tactgctacg gctggctctg
    26281 gacgacgcac cattttcaag atggctgaat ccacatttgg cgctggcaca aagaccgtac
    26341 gaggcacgat aaaggcaacc ttggctgtca tgtaatactg cacggcgata gacaagctac
    26401 cgtaagcctt ggtgttaggc tgggctgaaa tgcggtccgc tacttctttc tgcatcatga
    26461 ccacaaactc actaaaagga atgccactct caatcaagtg catgagaata ggcgtcgtga
    26521 tgtagtaagg caaattagcc actaccttga ttggcaggtt aggattttta aaattttgga
    26581 tatgttgcgc caaatcaacc ttgagaatat cttcgttaac tacagtcaca ttatcaaaat
    26641 cacgcagggt atctaccaaa attggcacca aacggtggtc aatctcaaaa gccatgactt
    26701 gggctgcacg ctcagccaga aactccgtca aggcaccaat acctggcccg atttcgatga
    26761 cattgacctg gtcatcaatt tcagccgtat ccacaatttt ttgaaggata ttggtatccg
    26821 tcaggaaatt ttgcccgaag gactttttaa aggtaaaacc gtgacgctcc agcactgcct
    26881 tggtcacgct ataatctgca attctcatct attctctttt ctattatctg ttactactat
    26941 tgtaacacat tccccttgta ttttgggaat gaaaatcata ccaaaaaact atctttcctc
    27001 atgaagaaag atagtcttgg aaatctttaa aagtggcctt aacagttctc tcgaaacatg
    27061 cgttcatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgtc gtactcaagt
    27121 acagcctgcg gctagcttcc tagtttgctc tttgattttc attgagtatc aaaaaaatca
    27181 gcttcttgat aacttctatt ttcgggtagg gtcaaatcca catcctcctc cacatcatcc
    27241 actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg cctttaccct
    27301 tcaatactag caaaatcaag caaatagcca tgcactagga tttgaaccaa aaggagatga
    27361 ttggtcatat ttttatcttc taaaccacct ctggcactag gataatcaga taccctgcga
    27421 atacggattt tttcacacat gagcaagttt cctcatatca atgatttcat cagccttatt
    27481 ccagactagg ggattatggg tcgcaatgat gataattcga ttttcatctt tcaaatccac
    27541 caagagattc ataacctcct ctgaattttc aggatcaaga gctgctgttg gttcatctgc
    27601 caaaatcaag ggtggatttt tcaaaatagt ttttgcaagg gcaactcgtt gggcctctcc
    27661 cccagataaa gtatagattt tttgttctaa atccaaatac cctagattaa ctttttctaa
    27721 agcccccact tgcctttcca aacgttctac ttttgagatt ttctgaccaa caaaacccaa
    27781 atccaaattt tctttgattg attggttttc taagaggccg aaattttgaa agagatagcc
    27841 catctggtct cgaaaatact cacgagtagg aatggttttt aaatctttcc cctgatagag
    27901 aacccttcca ccatctatct tttctagctt tcccaagata ttcagcagcg tcgtctttcc
    27961 gcttccactc tttccgatta aggcataaac cttgcccttc tccagcttga gattcaaacc
    28021 agagaaaatc gcgcggtcat taaatttctt ttccaatcct tgaatatcaa tcatcttatt
    28081 ttcctttcaa tactgccatg ctaccagctt cttctttttt gtcctgcctt actaaaatca
    28141 agagggcgtt aagcgtaaac aaagctacaa ctagagcgct aatcaaacca tctcttgtca
    28201 aaatactaga taggactagg ccaagcaaga gaactcctcc ttgcgccagt aaatacttgc
    28261 catgaagttc atagattgtc ataccagcaa gacgtttaat cataagctcc cgtctgaact
    28321 gctcaaaata gagaagattc atggaatcaa ataacaagat agccgtagac agggtcaaaa
    28381 tcgtcccaat aaggagagag taaaactcca cccgtttgtc atttagtacc ttggcaaaaa
    28441 atagctggct ttttaccaag taagaaacct tgtgatacag accttgctct tttagagctg
    28501 tgatgctgtc tccatatcga tctagtttca aggcactatt agccgtagtt ccccacaaca
    28561 tccctgcaac aggtcttgtt ccagtcgctt gcggcgttag aactacaata atcggatctt
    28621 ttaggtactg gcgtgttgtc ttgtacccat cattatagag gaaacgttcc tgtcctgttt
    28681 ctgtaaaagc tagccttacc tgtgggaggt agtgtttctg actcgtcact tctacacttt
    28741 cagatgaaaa gttttgcagg taatctgtaa acaatccttg gtagtagaca gactgctctc
    28801 gcaagctctc aggcaagatc agcccaaact ctccctcaga caagttttgc atcttgtcca
    28861 taaactctga agaaacggta atcttttctt ctatcagata gcgtggtgag acatagataa
    28921 cattccctga cggtgtgtag tcactgagac gattgccatc taggtccact tctgctccat
    28981 ctgagaaatt gtcaacattg ctcataatat aaaaagagtc tgtattggct aaccgttctt
    29041 cagtaaatgt ctgccactca cgattatcct tacgcgttcc ttcttcatcg gcaaatgcac
    29101 tagaccaacc aaaggataga cggtaacggt ctgaggactg gttccattta ttgctagctc
    29161 tctccatttc ctgcatttca cggtagtggg gtaggagagc tgtcgcactc gatccgacca
    29221 ccaatacagc taagagttgc cccaccatca tcaatgtcat catacgtttg agagggagtt
    29281 tccctttcaa tagatccacc agactatttt cctgtaaacc aagtagatag acgacactta
    29341 gtaaggtaga aatccctgcc aaggtcaatc cataaagtag aagagcaatg atgaccagtt
    29401 gcaccgttgc cataaacaag gcaccttgat accagagaat ccccaatccc aaaagactgg
    29461 ataccagcac tgagcagata agctgtctca catcttctaa cactggtctg agagcaactc
    29521 caaacaagct ctcaccagct attaagcgaa tccctgcctg acgaagggat ttgatccgat
    29581 aaatcagggt cagactcata aaggtcagca gaaaaatagc taaactcagt agcaccatag
    29641 gggtggccgt caatagtaag actatcgaaa atggatcttc tccattcgaa acaaagcctt
    29701 gataaccaag ctctttcaag gtggtctgta agctcactcc atccaaactt cctgatacaa
    29761 tcaagtaaga ccctaataaa tcactcgttt ctgcactctc cttggaggaa atggtcagac
    29821 cttctggaag ctttccctca ccataagtgg cataggtaaa gcgtgtttct ccagcttcat
    29881 ttggctcaac gattcgacga gcaatgagac tattgtgctc taccgccaag tgactcaaag
    29941 cctctgtcac ctcttcgcga ctagctactg gttgatttat catcattcct gtcacatcaa
    30001 cagaaggata gttaccaaat aaaatctctt ctcgatggtc aacggaagtt atcaccatat
    30061 aaagcgatac taataccatt gaaatcaaaa taaataaacg tttcatcatt tcctccaaaa
    30121 agttacttgg tcacttagtg agaaggtgac caagtaaagc taaacaatag ggctatacca
    30181 ttctaaacat tatagtagaa tgcaactttc tctccccaag aagtacgaat ccatgcacga
    30241 gaagtccctc cagcaccagc atatcccttg tcagatgaac cagtttttct gctaacaact
    30301 gttgaactat ggtattttga agggtgatag tagtttgagt aagcaccacc gttacctgaa
    30361 ccataagtcc aaacaccacc ttctgggtat tgaacggctg cagaggcaac tgatacacct
    30421 ccacctaatg ttgctgcaat gctcgctaca agagctaatt ttttaactgt ttgtttcata
    30481 ttgatactcc tctatttttg attacaagat tgttgagtta cttgctcctc tttccattat
    30541 caacgttgat actattatat taccaaatga tattctaaaa ttatttgttt ttctctaaat
    30601 tgtcaaaata gcaccctgaa atgaactttt atagtcatta tactccatct ttatcacact
    30661 atcaaggaca tcaatgtcct taaaatctaa ctatttcata ttatttttag cttatatcta
    30721 aaaaaacagt tctaaagacg aactttagaa ctgttttgat acgaggacaa ggacattttt
    30781 gtcactgatt cactatgttt ataaatattt tttgacatcc tcttgccatt cctctgtcaa
    30841 tttctttact agaaatccat ctccaattag cttcgcaaat gttttagaag actgataaaa
    30901 tgattcagct aaactaaaat ctctttctac tcttaatgct tgcttccaca aaaacataaa
    30961 tacaagaggt ttcttttgat aatcttgagt tttatccata atttcttgta aacacgatag
    31021 ataatcatta aaacaatcag ttactcctac cttttcaaga caacacattc ctgaaataag
    31081 agtatctcta attataaagt aattctctat ttgagttacc ttcttctgtt ccaaaagaaa
    31141 gagcattagc ttttcgattt gatttataaa tttggcaaga tcttttctaa tgagcatttg
    31201 ataaaaaaac aaacgaatca acaacatatc atttattgaa taagcttctt tttctataat
    31261 ctgaggcata tgttcctcaa gtattaactc tgcatattca ggccttctag ttctagaagt
    31321 atccaaacac gcctgcaata cttcacatgc taattgttct tctttaggaa gattatcaaa
    31381 gtatgtttta taaatctctt ccaaacactc ttccttctta tcgtactcct cttctttacc
    31441 atagattggt tcacgtaaaa tctggtattt caattctaaa taagcagaag gaagagctga
    31501 aaaatccggc ataaggctat aaactggaac tcctagccgg cgagcaatat agtctaactt
    31561 gggcaaactc ggttgcgaag ctccactttc aattcgcgac agttgacgaa ctgtcagttc
    31621 ttgctcatct ccacaaaaat ctggacgact aattcctttt tctatccgaa tctctttaat
    31681 tttttgacca attaacatca gacgcctcct cttctacctg cttcgaaaaa tactgtgaaa
    31741 cttaaaaaat tgtaacggct acatctttcc tactcataag atttcatagc ttcttccact
    31801 tctgccaaag taaccccaaa caactctagg cgtttgagga gttgcttgcc gttggaatag
    31861 ccgattcgga gagtctctcc gaggtattct ctacgcttac ggctgtctgc ccctgctaga
    31921 aaaccaaggc gaatcaaatc gctacgacta atgtcaaact gactctcatg ttcaaattgt
    31981 tctgtcacct gagctagagc cgttttcagg tcttcatagc tggcatgctc aattcccaga
    32041 gaacgcccct tggtcttgga cttgggaaca gcttcatctc gcttgagaaa ggcatgctga
    32101 actgttggaa tgaccgtcat gatcatgcgc cgaatccgtt ccccattaaa atctgggtct
    32161 gtaaagacaa tgactccatg acgttggtgc aggcgctgaa tccgctctat atcctgatca
    32221 ttgatggcag aacctcgagt ctcataggtc tccacatcga aataacgctt gagattgacc
    32281 gtatcatcac gcccttcaac cacaattact tgggaaattt tctctttcat tacttgctgt
    32341 ccaatccaaa aatgcgttct gcatttgcag tcgttgccgc cgctagctct tctgtcgtca
    32401 taccacgcaa gtcagcgata aagtcgacca catagcgagt ataggctgtt ttattttcac
    32461 gaccacgctt gggtacaggt gctaagtaag gcgcatctgt ttccaccaac atcttgtcca
    32521 aaggtaactc tttagctgct tcttggaggt cagttgcctt cttgaaagtc accactcctg
    32581 agaaggaaat ggtcatacca agatccacaa acttctctgc ccactcaagc gtccctgaaa
    32641 atgaatgcat gataccacca cgaggaccaa cgccctcact cttgataatc tcataggtat
    32701 cttccagcgc atcacgggta tggacaacaa aaggcaaatc caagtcctta gatagctgaa
    32761 tctgacggcg aaaaacctgc ttctgcacct ctttgggcgc tgtcatccaa tggtagtcta
    32821 agccaatttc acctaaagcc acaaccttgg aatgttttaa cttatccaac aagtaagcct
    32881 caacttcctc tgtataagta ccagcttctg taggatgcca accaatagtc gcatagagct
    32941 gctcatactc atctaccaac tccaaggcat gctcaatcgt cggtttatca aaaccaacaa
    33001 tattcatctg tgtcacaccc atctcatcag ccaaggcaat ttcttctgcc tcacgacctg
    33061 caaattcttc tacattcaag tgtgtatgtg tatcaaaaat catctcttct aacctcgttt
    33121 tctatcttct attataccaa aaaagaggag gggcacctaa tttttcggtt tcccctcctc
    33181 tcttcaatag agagctattc tgctatcttt tctatccgat attgcccatc tcctgtccca
    33241 cagttagaga caaaagagat tggctacatt gatagaatat tcctattcag ctaaagtatg
    33301 tgattatctt gggttctcac ttttctcacc catcactagg attgataact tctcaaaatc
    33361 ccccttataa tctaacttta agtagagaat agaattttct agctgttcta ttttctacgt
    33421 ctagtctttc ttcctagcaa agcaaaacca cttgttgcca ccactagacc aagactagca
    33481 agtgctgcac ttgatgctga acctgtgtta ggtaattgtt tgccagcagg tgactggtag
    33541 gtaacatctt gcattgttcc tgcagttgct tgcggtgtac ttgttgtctt aggagcagca
    33601 ttaggagcca ctggtctctt aggaactgta accatgacaa tggcttgcac tccaatcgtt
    33661 tctgcttcct tcacatcttc catagttttc gcattttcaa tctctttgag agctgcttgt
    33721 ttttctgctt ccactcttgc taaaagttct gctttttctt tatcagaaag cggtgcgcct
    33781 ttgatttcat cctgcttgtc cttggctgct ttttcaatgg catttttagc tgattctttt
    33841 tcagtagcta attgcttaga agcttgtgat tgagctgagt tttgtgaacc tgtgtgagct
    33901 gatccacccg cctggctacc accgcctgca ttcgcattag catctgagct tccagtattg
    33961 cctcccttat ctccacctgg tgtattttct agcttatact ctggtgtagc ttcttgagtt
    34021 acagattcac ctttcgcaga ttgttgaact gtatcttttc ctagaatcgt cactactgaa
    34081 ccatctggga atgtgattgt tgctgtacca tctccagcta cattgattgt cgctccgtct
    34141 aatgctgaac catttgcttg taaaatagca accttaactt tttcttcatc tgttaaatga
    34201 gttatatctt ttacatctac tctttgagca ggtgctttaa cagttgattt ttcagcagtc
    34261 ggtttagtgc tatcttgtgc ttttggatct tgtgctacca attgatttcc tggaattgta
    34321 atagctgaac catctttaaa gacgattgtc gctgtgccat ctccagctac ttcaacttta
    34381 tagtaaaatg aaataataac aggacaaatc gatcaggaca gtcaaatcga tttctaacaa
    34441 tgttttagaa atagaggtgt actattctag tttcaatcta ctataacatc gcttccaaat
    34501 ccatttgcat ctactgaact tttttacaaa aataaaaatc agtagactcg agttcctact
    34561 gatttttgat agaattcgtt tggattatgc agccaaaact ttgcgtcctt tacgacgacg
    34621 agctgccaat acgcgacgac catttttagt tgacatacgg ttacggaatc cgtgtttgcg
    34681 cgcacgacga agtttacttg gttgataagt acgtttcacg atgaatacct cctcatagat
    34741 tttgtattcg tttagccggc tataaagtga tcagttacta aacatacttt actattctat
    34801 ctgattcttt cacttttgtc aatagctcta ggcaaatgtt tccagctttt tcgaatgcaa
    34861 gccc
//
LOCUS       DAVEHY010000021        34606 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVEHY010000021 DAVEHY010000000
VERSION     DAVEHY010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.021"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..546
                     /locus_tag="VUZ44_001261"
     CDS             <1..546
                     /locus_tag="VUZ44_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320176.1"
                     /translation="QHLSRAMSRVHVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSD
                     KRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNL
                     KQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFK
                     KRIFIALNIKKERTKFVLSRA"
     gene            complement(645..2267)
                     /gene="groL"
                     /locus_tag="VUZ44_001262"
     CDS             complement(645..2267)
                     /gene="groL"
                     /locus_tag="VUZ44_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU0320177.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2283..2567)
                     /gene="groES"
                     /locus_tag="VUZ44_001263"
     CDS             complement(2283..2567)
                     /gene="groES"
                     /locus_tag="VUZ44_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU0320178.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2723..3118)
                     /locus_tag="VUZ44_001264"
     CDS             complement(2723..3118)
                     /locus_tag="VUZ44_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU0320179.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3196..3957)
                     /locus_tag="VUZ44_001265"
     CDS             complement(3196..3957)
                     /locus_tag="VUZ44_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU0320180.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3999..4625)
                     /locus_tag="VUZ44_001266"
     CDS             complement(3999..4625)
                     /locus_tag="VUZ44_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU0320181.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4641..4958)
                     /locus_tag="VUZ44_001267"
     CDS             complement(4641..4958)
                     /locus_tag="VUZ44_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU0320182.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4955..5254)
                     /locus_tag="VUZ44_001268"
     CDS             complement(4955..5254)
                     /locus_tag="VUZ44_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU0320183.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5539..5730)
                     /locus_tag="VUZ44_001269"
     CDS             complement(5539..5730)
                     /locus_tag="VUZ44_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU0320184.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5891..6565)
                     /locus_tag="VUZ44_001270"
     CDS             complement(5891..6565)
                     /locus_tag="VUZ44_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320185.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6571..7017)
                     /locus_tag="VUZ44_001271"
     CDS             complement(6571..7017)
                     /locus_tag="VUZ44_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320186.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7131..7634)
                     /locus_tag="VUZ44_001272"
     CDS             complement(7131..7634)
                     /locus_tag="VUZ44_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU0320187.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7631..7993)
                     /locus_tag="VUZ44_001273"
     CDS             complement(7631..7993)
                     /locus_tag="VUZ44_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU0320188.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8059..9924)
                     /locus_tag="VUZ44_001274"
                     /pseudo
     CDS             complement(8059..9924)
                     /locus_tag="VUZ44_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9956..10405)
                     /locus_tag="VUZ44_001275"
     CDS             complement(9956..10405)
                     /locus_tag="VUZ44_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU0320189.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(10529..11245)
                     /locus_tag="VUZ44_001276"
     CDS             complement(10529..11245)
                     /locus_tag="VUZ44_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU0320190.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12128..13543)
                     /gene="ply"
                     /locus_tag="VUZ44_001277"
     CDS             complement(12128..13543)
                     /gene="ply"
                     /locus_tag="VUZ44_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU0320191.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13554..13886)
                     /locus_tag="VUZ44_001278"
     CDS             complement(13554..13886)
                     /locus_tag="VUZ44_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320192.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13957..14565)
                     /locus_tag="VUZ44_001279"
     CDS             complement(13957..14565)
                     /locus_tag="VUZ44_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320193.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14578..15036)
                     /locus_tag="VUZ44_001280"
     CDS             complement(14578..15036)
                     /locus_tag="VUZ44_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU0320194.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15161..15963
                     /locus_tag="VUZ44_001281"
     CDS             join(15161..15611,15611..15963)
                     /locus_tag="VUZ44_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU0320195.1"
                     /translation="MNYEASKQLTDAQFKRLVSVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLNLEDLLMATLQYVREYRTYEQIAAVFGIHESNLIRRSQWVEVTIVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANYSGKKKCHAMKAQAIVTSQGRFVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(16727..16987)
                     /locus_tag="VUZ44_001282"
     CDS             complement(16727..16987)
                     /locus_tag="VUZ44_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320196.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(17046..17597)
                     /locus_tag="VUZ44_001283"
     CDS             complement(17046..17597)
                     /locus_tag="VUZ44_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320197.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFHSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(17587..17784)
                     /locus_tag="VUZ44_001284"
     CDS             complement(17587..17784)
                     /locus_tag="VUZ44_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320198.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDSISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(17788..18582)
                     /locus_tag="VUZ44_001285"
     CDS             complement(17788..18582)
                     /locus_tag="VUZ44_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320199.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLTKGQKVVNVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(18990..19415)
                     /locus_tag="VUZ44_001286"
     CDS             complement(18990..19415)
                     /locus_tag="VUZ44_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320200.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(19544..19927)
                     /locus_tag="VUZ44_001287"
     CDS             complement(19544..19927)
                     /locus_tag="VUZ44_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320201.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMASG"
     gene            complement(19949..20155)
                     /locus_tag="VUZ44_001288"
     CDS             complement(19949..20155)
                     /locus_tag="VUZ44_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320202.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFNLIAVNSDMPLGR"
     gene            complement(20142..20303)
                     /locus_tag="VUZ44_001289"
     CDS             complement(20142..20303)
                     /locus_tag="VUZ44_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0320203.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(20662..21618)
                     /gene="lytA"
                     /locus_tag="VUZ44_001290"
     CDS             complement(20662..21618)
                     /gene="lytA"
                     /locus_tag="VUZ44_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU0320204.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(21994..23364)
                     /locus_tag="VUZ44_001291"
     CDS             complement(21994..23364)
                     /locus_tag="VUZ44_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU0320205.1"
                     /translation="MNKKRTVDLIHGPILLSLLSFAFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQSLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(23670..24836)
                     /gene="recA"
                     /locus_tag="VUZ44_001292"
     CDS             complement(23670..24836)
                     /gene="recA"
                     /locus_tag="VUZ44_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU0320206.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(24891..26147)
                     /locus_tag="VUZ44_001293"
     CDS             complement(24891..26147)
                     /locus_tag="VUZ44_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU0320207.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKTSSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(26232..27248)
                     /locus_tag="VUZ44_001294"
     CDS             complement(26232..27248)
                     /locus_tag="VUZ44_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU0320208.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(27256..27774)
                     /locus_tag="VUZ44_001295"
     CDS             complement(27256..27774)
                     /locus_tag="VUZ44_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320209.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(27764..28207)
                     /gene="tsaE"
                     /locus_tag="VUZ44_001296"
     CDS             complement(27764..28207)
                     /gene="tsaE"
                     /locus_tag="VUZ44_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU0320210.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(28293..28913)
                     /locus_tag="VUZ44_001297"
     CDS             complement(28293..28913)
                     /locus_tag="VUZ44_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320211.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(29296..30159)
                     /locus_tag="VUZ44_001298"
     CDS             complement(29296..30159)
                     /locus_tag="VUZ44_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0320212.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            30505..32520
                     /locus_tag="VUZ44_001299"
     CDS             30505..32520
                     /locus_tag="VUZ44_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU0320213.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWFIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGEGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEVGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            32522..33154
                     /locus_tag="VUZ44_001300"
     CDS             32522..33154
                     /locus_tag="VUZ44_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320214.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            33295..33573
                     /locus_tag="VUZ44_001301"
     CDS             33295..33573
                     /locus_tag="VUZ44_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HEU0320215.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(34082..34495)
                     /gene="ndk"
                     /locus_tag="VUZ44_001302"
     CDS             complement(34082..34495)
                     /gene="ndk"
                     /locus_tag="VUZ44_001302"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU0320216.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
BASE COUNT        10476 a         7515 c         6031 g        10584 t
ORIGIN      
        1 caacatctta gccgtgctat gagtcgtgtg catgtccaaa tcatgaatca gtttcatcga
       61 aaatcccatg aatacaaggc tatcaagcgc tactggaaac tcattcaaca ggatagccgt
      121 aaactgagtg ataagcgatt ttatcgtcct acttttcgta tgcacttaac caataaagag
      181 attttaaaca agcttttgag ctattcggaa gacttgaaac accactatca gctctatcag
      241 ctcttgcttt ttcacttcca gaacaaggaa ccagagaaat ttttcggact tattgaggac
      301 aatcttaagc aggttcatcc tctttttcag actgtcttta aaaccttcct caaagataaa
      361 gaaaagattg tcaacgccct tcaactacac tattctaatg ccaaactgga agcgaccaat
      421 aatctcatca aacttatcaa gcgcaatgcc tttggttttc ggaactttga aaacttcaaa
      481 aaacggattt ttatcgccct gaatatcaaa aaagaaagga cgaaatttgt cctttctcga
      541 gcttagctga cttcaaccca ctacagttga caaagagcct ataaaaagaa gggttagtca
      601 ttccctcctt ttgtgttttt tataagttgt tttctataga aagcttacat catcccgccc
      661 atcatacttg gatccattgc tggagctggg gctactggtt ctggtttatt ggctacgact
      721 gcttctgttg tcaaaatcaa gctggctaca gatgctgcat tttgtagggc tgaacgactc
      781 actttaactg gatcaatgat accttgatca atcatgttaa cccactcgcc agttgctgcg
      841 ttaaatccta taccaagctc agcatttttc aaacgatcga taacgataga tccttcaaat
      901 cctgcattgt gagcaatttg acgaacgggt tcttccaaag cacggagaac aatattacgt
      961 cctgttgctt catctcctgt caattccaag gtagcaacag ctggaatcac attggcaaga
     1021 gctgttccac cgcctgcaac aataccttct tcaacagctg cacgagtagc gttgagggca
     1081 tcttcaatgc ggagtttcat ttctttcaac tcagtttcag ttgcggctcc gaccttaata
     1141 accgctacac cacctgacaa tttggccaag cgttcttgca atttttcacg gtcaaattca
     1201 gaagttgtag tttcgatttg agacttgata accgcaacac ggtgagaaat cgcttcagga
     1261 tttcctgcac cttctacaat aaccgtgcta tctttgtcca cggtcactct cgctgcttga
     1321 ccaagagctt caattgtcgc atctttcaac tcaagaccaa ggtcttctgt gataactgtt
     1381 ccgcctgtta agatggcgat atcttcaagc atggctttgc gacggtcacc aaaaccaggt
     1441 gccttgactg ctactacgtt gaaggttcca cgaatcttgt tcaaaacaag agttggaaga
     1501 gcctcgccat ccacatcatc cgcaataatc aagagtggac gattgctttg gagaatgctt
     1561 tccaaaagtg gcaagatctc ttggatattg gaaattttct tgtctgtaat caaaatgtac
     1621 ggattttcaa ggtcagccac cattttttcg ctatctgtca ccatgtactg tgaaaggtaa
     1681 ccacggtcaa actgcattcc ttctacgact tcaagctctg tttccatacc acgtgactct
     1741 tcgatggtga tgacaccgtc tttgccaact ttttccattg cttcagagat gtactcacca
     1801 actttttcag aacgagaaga tacggctgca acttgagcga tagcttcttt attggcaaca
     1861 gggatggcgt tgtttttcaa agcttcaact gctgcggcaa ctgctgtttc aatcccacga
     1921 cgaataccga ttggatttgc acctgctgtg acgtttttga ttccttcacg gacgatagct
     1981 tgggtcaaga ctgttgcagt cgtagtcccg tcacctgcga tatcattggt tttagaagct
     2041 acttctgata ccaatttggc acccatattt tcaaaatggt cttctaattc aatttctttg
     2101 gcaatagtca caccgtcatt ggtaatcaat ggtgagccaa atgatttttc aagaacgaca
     2161 ttgcgacctt ttggtcccaa ggttacttta acagtatctg caaggatatc gacaccacgg
     2221 accatagctg aacgggcatc tgatgaaaat ttaatttctt ttgacatact tactttctcc
     2281 ttctattctt caatgattgc caagatgtta gcttcgccta cgatgatata cttttcatcg
     2341 ccatctttga catcaagacc tgcgtgggct tcaactaaga cacggtctcc agttttaaca
     2401 cttggagcaa ccaagtcacc gttcaaggta cgaacacctt gtccagtagc cacaacttgg
     2461 gctgttttgg ttttttcttg ggctgaacct gcgagaacaa agcctccaac agtttgttct
     2521 ttttcttcta cttttaagac caaacggtcc cctaatggtt tcaacatctg atttcctcca
     2581 taatgagata gatattatta gcactcttta tacctgagtg ctaattcata gttctattgt
     2641 atcacttagt cagaaataat caagaaaaaa gtctgacttt ctcaagataa aaagcctgag
     2701 accaactcag actttttaat tcttaaaatg gcaattcttc ctcttccaag accaaatctg
     2761 ccaaatcttg gcctgcatta ttttcacgca tagcacgttg ggcacgactt tccaagagtt
     2821 ggaatcctgt cacaaggact tcggttacat aattcatctg accatttttc tcaaagcgac
     2881 gggtacgcaa ttctccatca acggaaatga gactaccttt ggttgcgtag cttgccaaag
     2941 tttctgctag tctgccccat aggaccatat tgacaaaatc aacttcacgt tcaccgtttt
     3001 ggtctttgta acgacggttg acagcgatag ttgctcgcgc tactgacttg tcattgttgg
     3061 ttttgtgcaa ttctggtgta gacgttaaac gtccaatcaa gataacttta ttatacatat
     3121 tttcttcctc ctacttatct attcgtagga aatcaaaaaa agttacagaa atttgtaact
     3181 tttcgagaaa attttttatt ttttatgaac catgaaacct gtcgcctgtt gattggccat
     3241 aatggtcata tctgtaatct gaacacgacg aggttgacta gtcacataga ctactgtatc
     3301 tgcaatatcc tgagcttgca aagcttctat tccttggtaa acggacgcag ctcgttcttt
     3361 atcaccatga aaacgcactg tagaaaaatc tgtttcgaca attccaggct gaatggttgt
     3421 caccttgata tccgttgcga tggtatcaat tcgcagtcca tccgaaaagg tcttaaccgc
     3481 agccttggta gctgagtaaa cagcggcacc agcataggcg tagattcctg cggttgaccc
     3541 catattgata atatgacctt gattgacttt tatcattgct ggcaagaaac agcgagtaac
     3601 cgccatcaga cctttaacat tggtatccaa catggtcaac atatccaact cctcatagtc
     3661 ttgataggga gccaagtcaa gagccagtcc ggcgttgttg accaagatat caatcctccc
     3721 tatcgtttct agaatatcag agcaaacagt cttcaccatg accatatccg tcacatctag
     3781 tggaaaagtc cagacggttt gatttggaaa gcttactgca aactccgact tgaggatttc
     3841 taatctgtct atccgtcgtc ctgttagaac gacatcctca ccctgctcca gataagcacg
     3901 cgcaatcgct tcaccgattc ctgaggttgc tcccgtaatc acaacatttt ttgccatctt
     3961 atttccttct agctggtcta tcagatatta acaacttctt aggcagtcca gtgtttagct
     4021 gagtcaaatg gtgttccgac aacttggtct tctgataatt caagcacacc acgtttttgt
     4081 ggagcatttg gcagatgcaa ttcacgagga ctgcacatca taccaaaact cttttcacca
     4141 cgaagttcac ctgggaaaat gagattccct tttggcatca tagctccagg aagcgcgaca
     4201 atggttttca accccacacg cgcattggga gctcctgcaa cgatttgtac agtcttatca
     4261 cttgcgactg caacttggca gatgttgagg tggtcactat ctggatgggc taccatctca
     4321 acaatttcac cgacaacaaa cttaggttcc ttatcattaa caatttcttc tgtaaaacct
     4381 tccgcctgca actcttggtt caaacgagcg acttgctcat ctgtcaaaaa gacttgaccg
     4441 cgctctgcag tttcaaataa acttgaaact tcgaaaatat tccaagccac tgtttcccca
     4501 ttttctttga ggaaaacacg ggctaccttg cctttgcgtt ccacattcag tttggcatct
     4561 ccgctatttt tcacgatgac cataaggaca tcaccgacat gttctttgtt atacgtaaaa
     4621 atcattgttt cctttttctc ctatttcaat cctgctaaaa aatcgttaat ttgctcctta
     4681 cttttacggt cgcgattgac aaaacgaccg atttccttgt ccttttctag aacaacaagg
     4741 ctaggaattc cgtaaacatc ccagagtttg gccaaatcca tatactgatc tcggtccatt
     4801 cgaataaagg tgaactctgg attggtctct tcaatctctg gtaaggcagg ataaatataa
     4861 cgacaatcgc cacaccagtc tgccacaaaa aggaagacct tcttgcccgc tttttccact
     4921 aaagatgcta attcttctaa acttgctggc tgtatcataa gacttcctcc tcatagacta
     4981 ggtcttcatt ttcatagaca aaggtataat gacggccatc ctcaaaaatg acgccaccaa
     5041 ccaagctctc cagactgctt tcgtaaactt gaacataaag ggtcgcaatt tcccccatgt
     5101 cggaaaaatg gtctcgcaca atctctgtca actcttcctg agtcttcatg agcttacggt
     5161 catctgcaac ttttttcgta gcaagagcaa ggcttccgat acctagcaga gccaagcctg
     5221 ccatccacat ttttttagct ttcataccat tcattttaac acaaaaaagg cttcaggaca
     5281 aatgaggaag cagcagaaaa gcaagtaaaa agcctcttcc tttaaggaaa aggacttctt
     5341 atactaagag caaactagaa agctagccgc aggctgctca aaacacggtt ttgaggttgt
     5401 agataaggcg acgttgacgt ggtttgaaga gattttcaaa gagtattatt cttattgcca
     5461 ggcacctaag ttgccaacgt agtaaccatc aggtgtgtag gtattgcgaa gcatcttacc
     5521 tgatgaagcc agataatact acttgccatt gtctttgacc caatcattcg caatcatgga
     5581 accagaagaa cttacataat accattctcc cttgtcataa acccaagtac tgactttcat
     5641 ggttcctgag caattaaagg caaaaaaact gtccaatatc attcgttttt taaaagcatt
     5701 cgacactaca tcatctacgc tgtagtacat agatacatca aacgtaaaag ccaaaatatc
     5761 gaaaaatata caacttttaa aggcagcatt tcatttttta aagtctaaca accatagaac
     5821 tgaaatcaga gcaaggcatc aatttcctac tctatagtac gcctattttg atggttgaag
     5881 tgaagatttt ttatttaacg tagacaattt ccaacttccc aaaagccaca tctccacgga
     5941 taatcaaggt tttgctggtt ggggctacag gagcgtcagc cttagctgca ccaaaggagg
     6001 tttctacttt caaatctaca cgccagtgtt gtggaacata gacggttgca tttccgaagg
     6061 ctacttcaat atttaaagtt gcaaaatcac ctagcatctc tgcattatca tagtagattt
     6121 tagcatcccc aaaagcgact tccacttggt catctacgag atcttgatct tgcttataga
     6181 aggtcccgct accaaaagcg acttccttat ccgtgacgac tgtttttttc ccattgtacc
     6241 accatttttt ttcattccag aacttacttg aatgcgtcag ataaccaaca ccaagtacca
     6301 ccaagatgct agcccaaata agagaatgat tggtaactgg taacaagtca taagcgtaat
     6361 ttgcaatgat gagcgccagt aaacctgtaa aaactgccga agtgagatga cgtctaagga
     6421 tggactcaat ggacttataa gcaaaaaaaa caatacctag taaaggccat attttaccat
     6481 ccaaagaagg aattccaaaa ttcccttgca gcaagatcca agctgctaaa accaataaaa
     6541 caataccaaa tgctttcttt ttcatgtttt ttacctcatg tttcttagat tttcttttag
     6601 gagggattgg taatgccgtg agacatgaac ctccttgtgc gtctgataaa aggaaatggt
     6661 gcccgttcct gaaaaggact tgtccactga gtaaatctga cggatgtttg cgatcgttga
     6721 cttggaaact cgattaaaat agcgaggcaa gatagactcc aactcataga gcttgaggcg
     6781 aacctcataa gcttccttct ggttatgagc gtagatcttg ctcccttctg tttcaaagaa
     6841 gagaatttct gacaggtcta gataatattc acctgtcccc ttgtaaaaag tcaacctcgg
     6901 agcctttgac tcttgcaaga gccgttgcaa gtctgcaatt tcatctgtca aagtgggggt
     6961 cttgatgaca atttcagtct cctctaaatt gccgtcaatc tcaattcgta acttcatcac
     7021 atctcctttc tgactctact atatcaaagc taagttagga atacaagggc aaaaaagcaa
     7081 gtggtcaatt tgaagcagta agtggttgta ggactagctt aacttacatg tcagaatagg
     7141 aagaaaagga atccccacac caaaccacaa gcatagccaa ccaagacatc cttgggataa
     7201 tgaacacccc ctaaaaccct caccaacccc agcaaagctg aaaagatcaa gcatactaag
     7261 ccaataggta gactagcatg cagacaggcc atggagatga tagttgccga aaagacatgg
     7321 cgactgggca tcgaccgtcc cgaactatcc ttatcaagaa ggggacagat atcccaagtt
     7381 tcataaggtc tcgggtgatt gattttctta cgaaacaggg acaaggtcac aaaacctgat
     7441 gcaggaataa gcacataaac cccaacttgc tgaccaagtc ctagttgcag gtaagtggtg
     7501 actagcaaga tcagatagac caggggcatg gcgactgtca tcaaacgatt gaaactgcgt
     7561 aataggaata aaagaattgg acgactagtt agtctggagc tgatatttcg ataccattct
     7621 tgataatttt tcatttatgc ttctcatact tttctagaac ttgttgagat gttttcccct
     7681 tggcaagcca atccactagc ttgtccaagc gacgtatttc ctgcatcaga ggatcatcaa
     7741 tttcctcaat acggacaccg caaatcttcc ctgtaattgc aattcgttca gggacataat
     7801 atggtgcttg tctaaaaaaa tctccgtaag taacatccct atccagacaa gcaagaacat
     7861 cactcacttc ataccctgtc aaccaactgg tcacttggtg aactgactct gcctttccac
     7921 cctttcgctc aacttttgca atcaaggcta agtagacagc agcaaatttc atattgtata
     7981 atttctgact catacttctc tctttctatg tgtactagta taaataagaa aaagaaggcc
     8041 gtcaagcctt cttttgattt attcttctgc ttcatcttct gtaaattgac tattgtacaa
     8101 gtcagcgtag aagccacctt gcgccatcag ttcctcatag ttgccttgct cgatgatatt
     8161 tccatctttc atgaccaaga tcaagtctgc atttcggatg gttgacaagc ggtgggcaat
     8221 gacaaaggat gtgcgtcatt ccatcaaacg gtccatggct ttttggatca attcctctgt
     8281 ccgtgtgtca acagaagaag tcgcctcatc caaaatcaaa agcggtgcat ccttaagaag
     8341 ggcacgagca atagtcaata gttgtttttg tcctacagac aaggtcacgg tgtcatccaa
     8401 gatggtatca tagccatctg gcaaggtcat aataaagtgg tgaattccca cagccttact
     8461 agcttccatc attcgttcat cactaatccc tatttgatta tagatgagat tgtctcgaat
     8521 agttccttca aagagccagg tatcctgcaa aaccattgaa aaggcatcat gcacttctga
     8581 acgcgtcata gccttggtat ccacaccatc aatgcgaata cttcccttat caatctcata
     8641 gaatttcatc aaaagattga caatggttgt cttaccagcc ccagtcggcc caacaatggc
     8701 aaccttttga ccagcatgag ctgtcgcaga gaagtcatag tcttgaacat tgacaccgtc
     8761 caccagaatt tctcctgctg acacgtcgta gaaacgtgga atcagattga ccagagttga
     8821 tttaccagaa cctgttgacc caataaaggc cactgtttga ccagtttctg ctttaaagct
     8881 aacatgttca ataactgcct ccgaatttgc cgcatagcgg aaggtcacat ccttaaactc
     8941 gacctgacct ttgaagtttt catcagtcag ctgcacttga acagggtttt ggatagaaga
     9001 atgcaaatct aaaacttgat taatccgctt agcagagacc atagttcggg gaagaacgat
     9061 gaagagtgct cccatgagaa ggaagcccat gacaacctac atggcataag acatgaaaac
     9121 aatcatgtca ctaaagagag gcagacgcgc tatcggagca gcgtcgttaa tcacataggc
     9181 cccaatccag taaatcgcta cactcaaacc acttgaaatc cccatcatga taggattcaa
     9241 aatagccata agacggttga caaacaaatt caaacgggtc aattcatcat ttactgctgc
     9301 aaatttttca ttttgataat cctctgcatt gtaggcacga acgacacgaa tacctgttaa
     9361 actctcacga gtgatactgt tcagtttatc tatcagcccc tgaatcaagg actgttttgg
     9421 aaagtctagc gtcatcaaaa cggtcgtcat caggacgttg acaatcactg ccacaagtac
     9481 ggcccaaagc cagtattctg aatgacctaa aatcttccca atagcccaaa tagccataat
     9541 tgaaccacgc gttaccactt gcaagcccat agtaatcaac atttgaactt gagtaatgtc
     9601 attggtagta cgcgtcaaga ggctaggaat tgaaaatttc ttaatctctg tctgcgagta
     9661 atccaaaact cggttaaaaa tatcacttct cagcctacta gtataagaag ccgccactcg
     9721 ggatgcaaaa aatccaactg caactacgga caagaaggca agaaagagca ttcccatcat
     9781 catgcttgcc ggctgccaca actcatctaa attagttcct tgactaccta gcaaatccgt
     9841 aattttcgag atataggtcg gcacttccaa ctctagatag accgaaaagc aagtaaagag
     9901 aatggctagt aaaatcatcc ccattctttt ctactaattc ttttggctaa tttctttatt
     9961 ctctcctcct attcccttga tattttgcct gtagttgacc gagaaccttc tcaaaaatca
    10021 gtaattcatc ttcatcaatg tcttccatca actgcttgtc tatgcgttca aaaaaagcct
    10081 taacctgttg catctgagaa cgtgctttgt ccgtcagacg aacaaactta gcccgcttat
    10141 caacaggact cgcctccaat tccaccaaac cattttgcac tatacgctta accagattac
    10201 tagcaacaga cttggtaata ttgagttcct gatcgatatc tttaatcaag accaagtctt
    10261 ggtttttctc gcgattatcc aaaaaatgca caacctgacc ttgcggccca cccataaatt
    10321 caatgccgca acgtttggct tccttttgca ccatcaggtg aatttgatga ccaaaacgct
    10381 taaagactaa catcggttta cccataatct cccccttcta aataaaaata gttctctgga
    10441 gaataattaa atttctatga gaactatttt cttgattaaa aaaatcccaa gtgattttct
    10501 cacttaggat catgttctat aggttaaatt aaaacccatc tacgttcgta taaatctttt
    10561 ggacgtcttc gtcgtcttca agaacgctgt aaagtttttc aaaggtttca aggtcttcgc
    10621 ctgacaattc cacttctgac tgaggaatca tttccaattc agtcacttgg aattcttcaa
    10681 taccagactc acggagggca acgatagcct tgtgaaggtc agttggcgct gtgtaaactg
    10741 tgattgtacc ttcttgtgct tctacgtcat ccacatccac atccgcttcg agcaattgct
    10801 caaagactgc gtccgcatct tcacctccaa atacaataac acctttgttg tcaaagaggt
    10861 aagaaacaga acctgaagcg cccatgtttc cgccgttttt accaaaggct gcacggacat
    10921 tggctgctgt acggttgacg ttagaagtca aagtatccac aattagcata gagccatttg
    10981 gcccaaaacc ttcgtaacgt ccttctgtaa aggtttcgtc tgtgtttcct ttggctttat
    11041 caatcgcttt atcgataatg tgttttggca cttgggcttg tttagcacgg tcgataacga
    11101 atttcaaagc tgagtttgat tctggatctg gatcaccttt tttagctgct acatagattt
    11161 ctacaccaaa ttttgcatat actttagagt tggctccatc tttagccgtt ttcttggcta
    11221 cgatattggc ccatttacgt cccattagga atctcctttt ttcacatttt aatctttctt
    11281 attataacac aagttttttt gattttcact agaggaaatg gattttatta gcaaatcaag
    11341 ctaggatagc actttacctg ctaagatggt cttgcctttc tatcttttta tcaacagaca
    11401 ctcatccaca ttcaaaaaac aaactagacc attatctgca aatagaaagt ttcagccaag
    11461 tttgacaaag tcagctcaaa ttactgtttg aagtttgtag atataagcga caaaaacaat
    11521 catactgcac cttttgttga cagtctactc cagacatatc atagttcaag taaatacttt
    11581 gaaatccaac agttcttata ggcgctattg tattccaaga aatcaataga agagtttcta
    11641 agcaaacctc taatactcaa taaaaatcaa aaagcaaact agaaagctag ccgcaggttg
    11701 ctcaaaacac tgttttgagg ttgcggatag ggctgacctg gtttgaagag attttcgaag
    11761 agtataattt acgtgttccc aagatggaga aattagacta gtacactggc acttctaaac
    11821 cattgctagc aattgatttg ttcatattta atttcatttt ttccataaat gggtattaga
    11881 tataaacagc aaaatatttc cgatacgtgt cattcttgaa tttccaatca tctaaaacaa
    11941 gtaaaggata atcaatcccc tgtatatcaa ggaattggct acccttttta cttttttaca
    12001 cattctgttt gatagattca ttttaacatc acgagcatac tccaatggaa atcgctaggc
    12061 aagagataaa ctttcagata tccgcagaga gatcatcgcc tctttttgtc gcaagcattc
    12121 tcctctccta gtcattttct accttatctt ctacctgagg atagagagtt gttccccaaa
    12181 tagaaatcgt ccgcttacgc actagtggca aatcggtttt ttcataaacc gtacgccacc
    12241 attcccaggc aagcccggta cactctctaa ttttgacaga gagattacga acattccctt
    12301 ttaaaggaat actagtggta aagtgagccg tcaaatcctg cccatttctg tcccaagcct
    12361 taggagtcaa gacttcctta ccttgatgat cataggataa ttcatcccaa gtaatataat
    12421 attgggcaac ataggcacca ctatgatcca gcagtaaatc tccgtttctg taagctgtaa
    12481 ccttagtctc aacatagtct gtactatttt gaaaggtcgc aactacattg tcacgtaaaa
    12541 aagaagttgt ataggaaatc ggcaagcctg gatgatctgc tgtaaagcga ctgccttctt
    12601 gaatcaagtc ctctaccatg tccaccttgc ctgttacaac tcgggcaccc gaacttgggt
    12661 cgccccctaa aataaccgcc ttcacttctg tattgtccaa aatctgcttc cactctgtct
    12721 gaggagctac cttgactcct tttatcaaag cttcaaaagc agcctctact tcatcactct
    12781 tactcgtggt ttccaacttg agatagactt ggcgcccata agcaacactc gaaatataga
    12841 ccaaaggacg ctctgcagaa attcctctct gttttaaatc ctctaccgtt acagtatctt
    12901 gaaacacatc tcctggattt ttaacagcat ctacgctgac tgtataataa atctgcttaa
    12961 aattaacaat ctgaatctgc ttttcgcctg aatggacaga gttaaaatca atatcaagag
    13021 aattccctgt cttttcaaag tcagaaccaa acttgacctt gagttgttcc atgctgtgag
    13081 ccgtgatttt ttcatactgc attctagctg ggacattatt gacctgacca taatcttgat
    13141 gccacttagc caacaaatcg tttaccgctc cgcgaacact tgaattgctg gggtcttcca
    13201 cttggagaaa gctatcgcta cttgccaaac caggcaaatc aatactataa gtcatcggag
    13261 cacgatcgac cgcaagaaga gtgggattat tctctaacaa ggtctcatcc actacgagaa
    13321 gtgctccagg atagaggcga ctgtcgttgg tagctgttac agaaatatca cttgtatttg
    13381 tcgacaagct ccgcttcttt ctttcgataa caacaaactc atcgggtagc tgattaccct
    13441 ctttgatgaa acgattttca atactttctc cctgatgggt caagagtttc tttttatcgt
    13501 aattcatagc tagtataaag tcatttactg ctttatttgc catcttctac ctcctaataa
    13561 gttcctggat tgagttgcat aaactcagac ttgttcagcg aaatcagccg tggttggact
    13621 aagtgatcca aaatttcctc gtacaattct tctgagacat tgcgtcgccg tctggctaga
    13681 taagaagtcg gaataaccgt attatccaac ataaatacct tatctaagtc aatcaaggtt
    13741 ggtcttgtaa aaggattacg agctagatcc ggctcttcta tcataaagtt cttgaccaaa
    13801 cgtctggtca agagagctgg tttgaaggtc tgatttttaa ccaactcttt gtttttagtc
    13861 atgctgttgt caatacagat atacatatga ttcttcacag ccaaatcgct actaatagtc
    13921 ggaaaaggca aataaagaac tacaacatct cctctcttaa tcaagcaaga gcaccccctt
    13981 ttctcctaat gtaacataga caggattgac caagtcttct gattgactca gaatttccaa
    14041 agtttgagtt tggcgcgctg tcaatttagt agcatcttgt ctcttcaata caaaatgctt
    14101 gtcgccaata accttgacaa tataatcctt ctccaaagct gactggtaaa tccacatcag
    14161 atgttgtctg tcctgagaac tcaagagaga aggattttca agcctcccga tagtctgata
    14221 aaaatcaaaa acaggagcta actcctgcca atctgattgg ctagttgtca aggctagaaa
    14281 aagggctttg cgagctgata cttcttggtt agccttgaga gttactttcc cctccaagtt
    14341 ttttagaaat cgggaaactc cagaaagcaa atttttctct aactgcgaga aataaaaacc
    14401 tttcgttccc agacataagt ctttcatgtc gctttctcta gcaaataaga gctcaaacat
    14461 ttgatagtaa aagaaaaata tctggcactg ggtcgcgctc atcttttcct tatcggcttc
    14521 tttttttaac cagagcaagg gcgacaggta gctggattga gacatttcct ctacctccta
    14581 ctctttttta actggagcat ctgcactagc tgccacttct tttgactgga tactttccca
    14641 ctggttaatc tcctctgaga taagaccttc gcatgtcttg acaaataggg caaaagcctt
    14701 ggtctttcct gcatatttct ccgtttggca ttgatagagg aatttttctt tctccaggag
    14761 ttgcgcagtt ttttggtaag aaatccaatt ttcctttgca ttatacaaat tgataatccc
    14821 ctcacacagc aagccgagac tggataaggc aaccgaaatc aaacggtagc gatcacctgg
    14881 cataggaata gcacaaaaga cagctatgag gaaacctgcc acgatttctg ttatttttaa
    14941 taccttatag cgcctacgat gttgaacgct tttctttaaa aaatgagcta tctgtacgtc
    15001 taatcgctct gtcaggtaca tttcttctgg cgtcatattc gtaactcctt tcatttactt
    15061 tgataatcat agtataacat atttgaatat caaagtatag taaaaactgg actataactt
    15121 attagacttc ctacgaaaca aaatatggta tagtagttct atgaattatg aagcaagtaa
    15181 acaactaact gatgcacaat ttaagcgtct tgttagtgtt cagcgtacca cttttgaaga
    15241 gatgttagct gtattaaaaa cagcttatca acttaaacac gcaaaaggtg gacgaaaacc
    15301 taaattaaac ctagaagacc ttcttatggc cactcttcaa tatgtgcgag aatatcgaac
    15361 ttatgaacaa attgcggctg tttttggtat tcacgaaagc aacttaatcc gtcggagcca
    15421 atgggttgaa gtaactattg ttcaaagtgg tgttacgatt tcaagaactc ctctcagttc
    15481 tgaggacacg gtaatgattg atgcgacgga agtacaaatc aatcgcccta aaaaagaatt
    15541 agcgaattat tctggtaaaa agaaatgcca cgctatgaag gctcaagcga ttgtcacaag
    15601 tcaagggaga ttgtttcttt ggatatcact gtgaactatt gtcatgatat gaagttgttc
    15661 aaaatgagtc gcagaaatat cggacaagct ggtaaaatct tggctgacag tggttatcaa
    15721 gggctcatga agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagccg
    15781 ctaacagctg aagataaagc ctgtaaccat gcgctatcca aggagagaag caaggttgag
    15841 aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt
    15901 aaacgcttcg gattacgaat gaatttgatt gctggtatta tcaatcatga actaggattc
    15961 tagttttgca ggaagtctat tatatatatg cacagacata tgaaatcttt ttgatacatc
    16021 cttcttttta catagagaga cagcagttat gatatattta tccatacaca acatcttctg
    16081 taccaatact acaatattgg tacattttga ttacacaatc gtttcaaaaa atatgatgga
    16141 agcctgagta ttttatagta actcccttcc tatcaactag atcaaccagt tgagtgttga
    16201 atgttgaaac accctagcct cagcaaagga ctatgagcag catttcctag ccaataggac
    16261 gctccaaatc acctattcta aatccatcac tagcttggtc agtaagatac agactgcaag
    16321 gcaagactga cgtggttgat gagattttgg aagagtatta caatcataga ttcaccagta
    16381 gacttgaccg cagatttaac tatagtagat tgaaactaga atagtacacc tctgcttcta
    16441 aaacattgtt agaaatcgat ttgactgtcc tgatcaattt gtcctgttct cgtttcattt
    16501 tactatacta aaaaaccacc tgaaacaaat caagtgacta gaggataaaa acaaagactg
    16561 ggcaaaaagt tttgaaaagc aaaaaacgca taatatcagg tcttgaaaaa ccttgatact
    16621 atacgtttga ttgtgggaag attgacttca ttttctcctg aaattgaagt tttttctagt
    16681 ttccagatat agacgaattc aatatagcca tctcgctaca attattttaa ccatcgagaa
    16741 aatttttcag aatttcaaaa atttcatttt gatccaatga aatgtcatca ttttgaagaa
    16801 tagttgactt cacaggctct aattctatca caaagcggtg catgtctgct tttaccgcac
    16861 tacttgatgt tatagccgat aacttttcat ctcctagcaa ggaagctgtc aaacgggtaa
    16921 ggtcattcaa atgcttttta atggacttac ttaaatcttg agcacctgta gcagagcgct
    16981 ctctcatatc cagccaagct ttagccttaa aaataattaa tactcaatga aaatcaaaga
    17041 gcaaactagg aagctagctg caggctgctc aaaacactgt tttgaggttg tagatggaag
    17101 ctgacgtggt ttgaagagat tttcgaagag tatagaccac aattactcaa taccgaatac
    17161 ccctgaatgg tttctttttc atgcaccaat atattataat aatcttcatc caataataag
    17221 gctgataaac tagcatcttg gtcaaaatat aagggaattt ctcgaccgtc cttctttaat
    17281 ggatattctg gtaaaatact aaatagttca atcatagaat gaaactcagg attagttgtt
    17341 gtaaatcgaa aaagctgcgc tttctcatct ttctgacttc cttgatactc tcccaattct
    17401 aaaaagtgat tcaaggtagt ataaaattcc ttatttttta cttcatcaat gatgaccata
    17461 tcataatctt ttgttgtgcg acttttaaat ccttgcgaat ccaatacgat agaggtagca
    17521 gttcccccaa tcagaacata atagttctga aaatccgcaa acatttcttg aaaaataact
    17581 ttcgtattag ctggcatcat cttctcccag atactgtaat atcatatttt ctagtgcttc
    17641 actctcttcc tctatacgtg ggtcatcatc atcttttaag gtcaaataaa gagaaatcga
    17701 atctacaaat tgtttatcat gattattttt aaaatcattc caaaactcag atacaaaagg
    17761 acgatatttc catatctcta gcatctttca ttttaaaaca tgctgagaaa gtggcaagga
    17821 taactgattg aattttctct gccatatgac atagctagta ttttcatccg tttcagctaa
    17881 aaaagttgaa tgcgacaaag cataagcacc accatataga aggttagaaa cagattttat
    17941 ctgctttata tcgccatctg gcaataaaat ccgttttttg atgggattaa ataaacatga
    18001 cacggatttt aagaataatt ctttctttga caccgtatat gtgtaaagct tattttgctt
    18061 gtttaaccaa tataaagctt taaaagtcct caaacaccta taaattgttg agtttggaag
    18121 tccagtgact tgtgaaagca aatcaacatt tactactttt tgaccttttg tcaataaaaa
    18181 ggcaatccac gttaattgtt cgctaggtgt taattcctta gggatttcag tatcattcgc
    18241 attgagtact agtcccaatg gagggaagaa gaggtttccc ttaaagtcta caaacggaac
    18301 tctagcttga agtaattgct ttttttcact gtctgataac ttcgaaaaca ccaaaacaac
    18361 atccatattg gctttttcac ccatagtgcg agcctgagta acaaatgaac tcaaactccc
    18421 ccttctcttt tctttaatca ataaaaatga ttccttatga aaagtcattt gagtatactc
    18481 aaaccttttt acaaaactga ttggtaaagt caaagtcagt tcctcaatac tgacatcaac
    18541 ataaaaggat tgaaaaattg acattatctt tttgacattc atgttttttc cttattctat
    18601 catttttatt atattttatc attcggtata ataaaatata agttttttga taaaataacc
    18661 aaaaactact cgctatcccc tctcacatta ccctacatat cgtttgacat gcgactgata
    18721 gttcaggaaa acttcaagga gaacttttct ctcatccact atgcaggact tactatttca
    18781 cttctactcc tataggctca atttgacact tttctttttc gaattgctca tatgcctcct
    18841 gaatagtgag ttcgatttat ccaaatttat ttttgtctat tttgatgaat acttccacga
    18901 agatagtctg aaaatgaatt tgcaccaatt ttccttctct ttttaagcat attattccag
    18961 atatgattgc cctcttattc agtaataaat tacgctttaa acgcttcaat cagtatatct
    19021 cctgttgtca tatgttctaa agaaaattct tctacatatg gtttaacatc tcttaggtta
    19081 ttacttccta atatcccatt atgctttttc gctaagaaaa tagaagtcgc ttctccctta
    19141 ccaataatct tgttactatc atgatttctt gttaaatctc tatataatgc gtattcttca
    19201 gttccaatgt ctatgctcac aatctcagct gaacccttag ttaccaactg gtctatccta
    19261 gattttaaat ggggaattgt aggtatattg atttcatcat acacctcttg tggaataaca
    19321 attttaccca aatagagctt ttctaaaaga tgttcagtgc caacccataa aaatactgaa
    19381 atacaatctg catcaataaa tacacgacta gtcaaacgac aactcccccc tcttcatcta
    19441 gcccatatac aatatcatat ctgaaagcat ctagtaacag ttcctcatac ttcccttgcg
    19501 aaattctgtt attttctaaa agttgttcag ttgaattaat atattatcct gatgccattt
    19561 cttttttact ttctgacaaa ggacgatata aacttgtatc atagcctaat cttgaagctg
    19621 tctctataac actaatatcc atatttttaa tttcttctgc atcaaggtat ccatcattcc
    19681 tcaatctata taacatagct ttatgactga taccataaaa ctgacccaat tttataatat
    19741 cttctacttc aagatgagtt ctattggcat tttctctgat ttcctcaacc atcctataca
    19801 gtgaagatgg gaaaattaaa aaataagaag caaactgatc cgcttttctt tcagtttcat
    19861 ctccttcacc aatcaagata agactgactg aactcttctt cacctcatca taataaagat
    19921 gatacagttc atgtgctaaa gaaaatcttt accttcctaa tggcatgtct gaattgactg
    19981 caatgagatt gaactgagtt cctttataac agactccgct aatattcttt ccgagtccat
    20041 aaaataccag cgtcaaattt tctatctttt gtaccaattt aaaaatatct atcggcgatt
    20101 caccatcagc tcccaacttt tttctaagat ttgaagcttt attacttaaa tccattcgtg
    20161 atattccttt cacctttttc cattttggca atcatgcttt gattcaaaga caaatactca
    20221 gcaatcttat cttgagtaag atttgaagat attctaagtt cttttattct ttttccaaca
    20281 tcacatacat ttatcacata catttatcat attcatacac ctctcataaa aagaatagca
    20341 cactcttgtc ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg
    20401 atgctgctta aaaatctaaa attgatgagt tcctatcaaa aatcgtatct tcaacctcaa
    20461 aacagtactt aaagctatcc gactcggttt acattgtcaa atttagattt tatttgagca
    20521 taactttcta gtttgctttc tgatttttgt ttaatatagt agcaaacatt gaaggaaata
    20581 tctccacaaa aaaacgcata ctattaagct ttttcaagac ctaataatat gcgctgttct
    20641 gatttgaaag acattccatt attattttac tgtaatcaag ccatctggct ctactgtgaa
    20701 ttctggcttg tctgccagtg ttccgtctgg tttgaggtag taccagcctg ttccgtccgc
    20761 tgactggata aaggcatttg ataccatggc gccttcttta gcgtctaagt agtaccaagt
    20821 gtccttgtac ttgacccagc ctgtcttcat ggcaccttct tcgttgaaat agtaccactt
    20881 atcagcgatt ttcttccagc ctgtagccat ttcgcctgag ttgtcgaacc agtaccagtt
    20941 gccgtctgtg tgcttcctcc agcggtctgc aagcatatag cctgaactgt caaagtagta
    21001 ccaagtgcca ttgattttct caaacttgtc ttttggataa gagccgtctg aatgtacgta
    21061 ccagtagcca gtgtcattct tctgccagcc tgtttcaatc gtcaagccgt tctcaatatc
    21121 atacttaaac tgctcacggc taatgcccca ttttgccaag taagggtatg gatccacatg
    21181 gtctgagtgg ttgtttggtt ggttattcgt gcaatactcg tgcgttttaa ttccagctaa
    21241 actccctgta tcaagcgttt tcggcaaacc tgcttcatct gctagattgc gtaagagttc
    21301 gatataaagg cggtagtccg tcatgaactc ttctttagtt gaatggcttt caatcagttc
    21361 aaccgctgca taggtctcag cattccaacc gcccccaacg tcccaggcac cattatcaac
    21421 aggtcctacc tgcatgatgc aaccgttccc aacaatgtgc gagaaaaaac ctaattctgg
    21481 gtctttccgc cagtgataat ccgcttcatt ctgtacggtt gaatgcggat tcccagttga
    21541 gtgtgcgtgt acttgcctat atggttgcac gccgacttga ggcaaatctg ttcttaattt
    21601 actcacatta atttccatat tctactcctt atcaattaaa acaactcatt ttttacaatc
    21661 cagaaccaga aactccttta tttctacctt acaaagaaga caatcttagt cacgattagg
    21721 cttgtagata gaacctcaaa acgcactatt ttgacactgt aaataggact gacaaggtct
    21781 gcattctatc tacaataaca ccccagacta aaaagctttt caaaagtata tttttacagt
    21841 ctctatatgt ccttttcata aatactatac tttattatat catataaaag aagtcagaag
    21901 tctgttaaac tattttcaac accaaactaa agaagagaac acaagttttt tcgatgttca
    21961 ctagaggaaa tggattttat tcagtaaatc caactaggat tgcactttgg ttgccaagat
    22021 tgcctttcct tcttttatca agggatgacg gaatagtgag aagtacagtt gaactgtcat
    22081 ggcaacccag ataagaggtt cacaaaggat aacaccctta tatcctgccc aaggaataat
    22141 caaaaccaca aaaacgattt ttccgattag ttcaataaag ctagaaacta gaggaaggat
    22201 cttctgcccc aagccctgca agcaattgcg ataaatcaac aagaggctca aaatgggata
    22261 aaaggctgaa ctgatttgca gatagagact tccattttct atcaagtaac catctgtcga
    22321 actagccaag aaggaaacca aggctggact ggcaaaaaag aggaaaatac aaacaaaaac
    22381 tgcccaggat atacttaaac gactgccgat tcgaagacct tgagcaatgc ggtcaggtcg
    22441 cttagctcct agactctgag aagcaaaggt cgtcattgat gcagaaatag cggtcatagg
    22501 aagaagggca aaggtcataa tgcgtcgagc tgccgtctga gcactaataa tcactgcacc
    22561 aaatgtatta acagaagact gtaaaatcac actgccgata gatacaattg aactcatcaa
    22621 gcccatagcc aaaccctgct ccaagagatc cgcgtacaag cttttgtccc atttgaaatg
    22681 tttaaactgt ggcaagagtt ctggcacact tttacgaata taataaaagc agagaaccgc
    22741 tgataaacct tgcgaaataa tggtagcaag tcctgcggat tgaactccca gatgcaattg
    22801 cgtaataaaa tagagatcca gaaccacatt aaccaaggca gagaaaatca gaaatcccag
    22861 ggctgctaga ctgtcaccaa tagaccgcaa caagcctgca aaaagattat aagcaaagct
    22921 gacacctaca caggtcacaa tcatagaaat atattgataa gattgaggaa gaatttctgc
    22981 aggagtatct aagtattgca agagaggata caagccaaga aagcccagca acataactag
    23041 aatgctcaaa agagcaccta aaatccaggt ggctgctact gcttccttga ttttagtgaa
    23101 attccgagcc ccataataac gagcaatgac aatccccatg ccattgccaa caccaagtgt
    23161 aaaacctaca atcaggtcaa aaatcgctgt cgtcgctcct actgcagcca aggattcttg
    23221 accaagaaat cgtccaacaa tcaagacatc agcagtgtta tagagctgtt gaaaaatatt
    23281 tgatagcaag attgggaagg cgaagcttaa gagcgagaga agaatcggac catgtatcag
    23341 gtctactgtt cgttttttat tcataaagct attatatcag ctttccagag gagcgacaag
    23401 aaacagcaaa ctatatatag cggaatgaaa taaggacagt caaatcgatt tttaacaatg
    23461 ttttagaagt agatgtgtac tattctagtt tcgatctatt ataattggtt gagtttggaa
    23521 tagtacgctg tagctgctaa aacatttcta gaaattaatt tgactttcct aataaagttg
    23581 ttcatatctt atttcaagct actatatata atctaaaaac ttgaatcaaa aatcgaaaaa
    23641 gtagcggatt tctccactgc tttaacagct tattcttcaa tttcgatttc aagttcatcg
    23701 cctaagtcaa gcgtaacttc ttcattcact gcttcttctt tctttggctc atcttttttg
    23761 ttttcagtat cttgttctga aacttcttct ccatcaatca agccaaattt agaacggact
    23821 tgcttatcaa tttcatcaaa gatttctggg tgctctgcca agtatttctt agcattctca
    23881 gaaccttgcc caattttttc atctttgtaa gaataccaag cccctgcttt tttgataata
    23941 tccaaatcgc ttgcaatctt caaaagctca ccagtcttag aaattccttc tccgtacata
    24001 atttcaacta cggcttcctt aaacggtgga gctaccttat tttttacaac cttaatctta
    24061 gtttctttac cgacattggt ttctttttgg tcaccagttc ccttaatttg tgtattacca
    24121 cgaacatcca agcggactga agcatagaat ttcaaagcac gtccgcccgg tgttgtttct
    24181 ggatttccaa acatcactcc aactttttca cgcaattggt tgataaaaat ggcaattgtt
    24241 ttggttttat tgatagaggc gccaagttta cgcatggcct ggctcatcat acgagcctgc
    24301 aaaccaacat ggctatctcc gatatctcca tcaatttccg cacgaggaac aagggcagca
    24361 actgagtcga ctacgacaag atcaactgca cctgagtcaa tcaattttcc cgcaatctca
    24421 agaccttgct ctcctgagtc tggttgagac aagagcaatt cgtcaatatt gacaccaagg
    24481 gccgcagcat aagctggatc aagggcatgt tccgcatcga taaaggcagc aatcccacct
    24541 tctttttgcg cttgtgcaac tgcatgaagg gcaaccgttg tcttaccaga tgactctggg
    24601 ccatagattt cgatgatacg tcccttagga taaccacctg agccaagggc aatgtcaaga
    24661 gctaaagaac ctgagctcat cacttgcacc ttttgctccg cacgttcacc caaacgcatg
    24721 attgatcctt taccaaagtc tttctcaatc aatttaagag cgtcattcaa ggccttttca
    24781 cgttctgccc caaatttttt tgaaatttct tctaattttt ttggtttttt cgccattcta
    24841 ttctcctaca ttctaatgat cctcagacct atctactatt atatcaaaag ttagtcactt
    24901 aataaagcct tgcgaactag gttaaaggca tgcataaccg caatgtgacg tacatctgct
    24961 cggcttctgc ctccaatatt aaccttgata acctcagttc cttgatcttg cgccaagcct
    25021 atgaagactg tcccaactgg gtgtccttct aggctatctg gtcctgccac tccagtcaaa
    25081 ctaattccaa aatcagactg ggtcttgctt cgtgcctgct cagccatctt ctgagctgta
    25141 aattcagaca ccacaccatg ttcttccaaa ttcttggcag gaatatccaa catccttgat
    25201 ttttcctcca agctataggt cacaaaacca cccttaaata tacttgaaac tccagaaaaa
    25261 ttcgccacgg tagcttggaa aagacctgcc gtcaaactct ctgcagccgc gatggttttc
    25321 ccttgccttt tcagttcttc taccacaatg ctggctaaac tagtttcttc cccataacca
    25381 tagcaaaagt ctcgtaaaga aattccttcg aaagtctggc agtccaagat ttgattttcc
    25441 aagatatcca gcgcttgatt cgcctcttct tgactgctag tctttgttga cagacgtaga
    25501 gtgacttctc ctgtcttggc ataaggggcc aaggtaggat cgatctgatt atcaattaaa
    25561 tcagccaaaa tcgtaaccag ctggctctcg ccaatcccaa agaaacgaag aactcgggaa
    25621 tacagcttgc tccctgtcat caacttgggt agaagttggt ttaagaccat gggtttcaat
    25681 tcacttggcg gacctggaag gacgacatag gtcactccgt ctacttctaa ttttcctcca
    25741 acagccagtc ctgtttcgtt tggcagtgga atcgctcctt ctacaatttg agcttgtctt
    25801 tcgttattcg gtgttcgggc atagtctggt cgcagggcaa aaaagatatc caacttctcc
    25861 tgagcctgag gatcaaagac taatgctttc cctaaaaatt tagctagggt ttgtttggtt
    25921 aggtcgtcct cagttggccc caaaccgcct gtcaaaatca ccagactgct acgttgactg
    25981 gcaatctcaa gcaaagacaa gagacgaact tcattgtctc ctacagccgt ctgaaaatat
    26041 acatctaccc caatctcagc tagtttttcc gacaaaaact gggcattggt gttgacaatc
    26101 tgtcctgtca aaatctctgt tccaacagca atgatttctg ctttcatgtt tcctcctacc
    26161 tatctattcg tatttttttg aaaaaatcgc aggaattttc ctacgattga tttttttatt
    26221 tgtatcaaaa gttaattatc ttcatcacca acaggtgctc tgccaaataa atcttcaaat
    26281 aaaaccgcat tggtttcaag ctgagtaact tcttcttgtc ccaaagaacg tcggagtata
    26341 ttttgcattt ccaacatatg tgctctcgaa acaatctggt aagaaacacc ttgaagtatc
    26401 tctccttcac cctgcaactg ctgagtttca atggttttaa atgaatcttt atagcctagc
    26461 aagttaggga tactttttgc agacaaatca atattggtct gcatattgtc actcaaagct
    26521 tttagaatct cttgataatg accaatgcta tttaaactga gagctttttc catgactttt
    26581 tgaataactt cacgttgacg tttttgacga ccataatccc cctcaggatc ttggtaacgc
    26641 attcgtgcat agactagggc ttcttctccc ccaatatgtt gctccccaac accgatagaa
    26701 atggtattaa attcttcttg gtcactgata gaaattggga aacctaggat attattgact
    26761 gtaatacctc ctactgcatc cactaatttt tgcaaccctc tcatattgac catcacatag
    26821 cgatcaatat ggatattcat cattttttga atggtttcta tagcaagctc tgctccacca
    26881 tctgcatatg ctgagttcag tttcgcttca tgagcctgac cattccctga ttcaatgcgc
    26941 gtcagaatat cccgctctaa actcatcatt gttgtttttt tcgttttagg attcactgtc
    27001 atcaagatca tgctatcact tctaccgacc caagtttcag ttcgttcaac atttccggtg
    27061 tccactccca ttaacagaat ggttagaggt tcagtcgctt caataacctt ggtttcttcg
    27121 ccgatttttt tataggtttt agctaaggtt tctgtccctt gttgataaat agtataagca
    27181 aaaacaccta ctcctactac agttacagaa agtaaagcta gcaccattcc aataattttt
    27241 ttaaccatat ttctactaac ctatcagttt acccatcaag taaacatcga taaatttccc
    27301 ttcttctata tatgccccac gctcttggct accttcaatg acaaagccat gcttttgata
    27361 aagatggact gctgcttgat tacgagtttg gacagtcagt tggagacgac gcagaatgcc
    27421 acttgcttgt gcccactcta tcgcttcttc tagcaacaaa cttcccaagc cattattcca
    27481 atatcttttt ccaatcacaa tgaagagatc tccaatatga cggactctct tacgctgatc
    27541 agctgtaata tttacaatac cagcaatttt gccatttaag aatgcaagta aggttatctg
    27601 attgtccgaa ctagcttgct tgttgaggaa tatttccatc tcctcactag tcaagagaat
    27661 accatctccg tctaggctgg taaagtctgt ctccaaactc acacgattta aaaaggccac
    27721 taattcagct gcatctttgg gctctgcttc cctaatgagc aattcatact ccatattgaa
    27781 gctcctctga caatttctca gcacgcaaac cctttgcctg aaaatttaaa cggcgtccat
    27841 ctgcttcttt tagaatttcc aattctaaat aagcatctgg caaggcatct cctaagagat
    27901 ttccccactc aataacagtc acgccgccac caaagataaa ctcatccaag tcgatagaat
    27961 cagcatctcc ttcaatacga taaacatcta ggtgataaag tggaagtcga ccttcatact
    28021 ctctcacgat agtataggta ggacttttaa tcatttgaga aatctgtaat ccttttgcaa
    28081 gtcctttagt aaaggtcgtt ttacctgcac ccagttctcc aattaagatt aaaacatcat
    28141 tctttgctaa tagatggccc aaacgctccc ctaaggcttg caactcttct tcatttttta
    28201 tgtacatact cttattatac caaaaacttt tcttttgtgt ctattttcct actaaactta
    28261 tcatcataac atccataaaa aacaggcttt ctctaaaaga aaatgagcgt aacaatgacc
    28321 aatacaagat ctcggaaaat atgaccataa aaggaaactt ccttcttaac cgaatttggg
    28381 acaagatagg ctgcaaaaaa caagcccagt ccaatataaa tcagaagtga gacaatggtc
    28441 attggatttc ttaagaaaag aagtgttgct aaaatagtca ccaacactgt cttttttctg
    28501 tctagcatag caagaaaatc gcgcacgtat tttttcaagg gtaaaaaaat cagcaaatct
    28561 agcccaaata ggaaaaagaa ggatggcaat aaaaagtcaa ctaattcttg ctgcagcgta
    28621 tttttgatga acaagttatc tgacaaaaca agaacagctc ctaacaaatt aattaagagt
    28681 aacatactgt aaaaaagctt caccgacttc ttactggcta ggacactatg gacttcttgc
    28741 ttacgggtat aaagataatt tactccagca cagattcctg aaacgaaaac catgcttccg
    28801 atgaaaaaag ctgtactttg tttaaaggac aagatgcatt ccttccataa gaaacagcta
    28861 ctcaaactga tttgaattaa agctaacaaa aataagattc tcattgattt catcttctct
    28921 ctcccttcct accaatcatt atactaggag aaaagagaga actgtttcta atcttctcaa
    28981 atgtctcttt aagacgctaa acaaacacta gagactaata ctcaatgaaa atcaaagatc
    29041 aaactaggta gctagccaca ggttgctcaa aacactgttt tgagattgca gatagagctg
    29101 acgtgatttg aagagatttt cgaagaatat aaatttgaaa tcatgaaaat ccgtcaaacg
    29161 ggtggttgtt ttgtctcgca cctcacggag cgagacggac tcagagtcac ataattataa
    29221 ggctgatagt attaatctaa ctatcagcct tacaggttat ttaacgtttc agaaaaacta
    29281 taatgtcaag attaactaaa cagtatctag ttccttcaaa taattttcta tcttcatcaa
    29341 cattaaagga ttgttataaa tcttacataa ctctcttgct tctatataat aatttttgac
    29401 ttgttctctg tctagaaatt tggctccagc atttcctaca agaataagta gaggagccaa
    29461 ttggtagctt gtctgtcttt gtttacagag ttcaatcgtt tcaagagctt cttggatggc
    29521 ttcattatat ttttcctttg atactaggta gtgagcgtag ttgtaacgaa ctctgatgta
    29581 gccaaataaa aactcttgat ggtccaaatt ttttgtctga tacaactcta ttaaatgaga
    29641 gtagtttgcc tcatattctt gttcacgacc cactaaggaa tagaaattag atagagtatt
    29701 caacgccttt aaataaatca gagtatttga agagactttt aataatatat tttccaatga
    29761 agaaattgcc tcacacttac tgtcatattg atagaagtca ataatagctt taatccattc
    29821 aaggtaagtt cggtcttcta gtgttagaaa agtacttcgt tcaatctcta ttctataaat
    29881 atattccaaa tcgtcataat ttctatcgtc taatagtcga gcagacaatt gcttgaaatt
    29941 agagaggtta gatttaattt caatttgttc attaaaaaaa taatctaatg gtacttcaag
    30001 tcgttgagag agtttgaaca aaaggtctgc ggagggaatg aaatgccctc tctcaatttt
    30061 actaatctgg ctttgttcac aaattccttc tgcaagagtt tgttgggaga gtctcaactc
    30121 ttttcttttc aatctgaatt tctctgcgag tgtactcatt aaagataata aaccttccta
    30181 tttgcttaat tgcattataa aatttttagt tcaaaatagc aagttaaaga aataaataat
    30241 tctttatggt aataaactaa aaaaagtcaa aaattacata aaaatgcttg accgaataat
    30301 atatatatat taaaataaaa acaaggaaaa agaaaggggt ttcattgcat gagaaaaaaa
    30361 cgtggaatta aaaaattagt tacatttgat gcgggatggt aaagaataat tgaagaagat
    30421 tcttttatca atagtttagt aagcttgtta gtttatagag ggcaggggta tttctgccct
    30481 ctgttttaga ataaggaatg cactatgaaa aaattattta tactcatatc caacctgctt
    30541 gctagtttgt tctttgtttg ggtatttacc atttggactg atacatatgt ctcccattat
    30601 taccccaacg ttgttgtacg tgattcttcc cctgaaacaa cttttcagca tgttgctaca
    30661 cgcttggaaa aactagcaga agaaacagat agctttattg cgattcaaca ccaagatcct
    30721 aactcagaag gtactacagt tttttcttat acgacctttg gggacggaaa gttgcctgat
    30781 gggcttcagg aaaaaaatct agaagatgct caaagtagta gtgttgaaac aaactatttt
    30841 gtattcgatg gacacctaga tattcacttg ctaagggaag agctaagtca acttggcttg
    30901 actaacatgc acctgacaat tccatctaaa ctatctacgt taatggctat ctttagtaac
    30961 ggatttcagt taatcagtct attaattttc atcttaacct ttgtagcact gactttaatt
    31021 agtcaaatta gccaattacg gtcatcgggc attcgcctca tttcaggaga gaaacggtgg
    31081 ttcattttcc ttagaccagt tggtgaggat ttgaaagcga tagctgttgg tttcagttta
    31141 gctggcgtgc tcgccattct tatgcaaaaa attctgtcgc ttccaacgca atccctaatg
    31201 accataggag aaggcttgct cagttataat ctcatcttgt tgtcgatctc cctgtttttc
    31261 gctcaactct tcgcagttgg gataaaaaag atacacctga tgcagattat aaaagggcaa
    31321 gtgcctgtca gaggaatcat tagtttgatt ttaatcggtc aactattagc gattattatt
    31381 gtaacgctgg gaatagggag tagcttaaag tattcccaag cctggcaaca gcatcggatt
    31441 ggacaagagg cttggagtca ggaaagacaa ctgattaccc tatcaatcag ccgtgaagga
    31501 acgagtcctg gttttgatga acaagctcaa aggaaactca gaacttggta tcaattgatg
    31561 gatctggctg tttcagaaca aaaggctttc ttatctagac accagttaat tgaccgtact
    31621 ttgcaaaatg gcatggcttc ctccaaaaac ttgataacct ctacagaatg gcacgattac
    31681 aacccgaatg gcaatgtcct tatcgtcaca ccgcaatact tggaacgtca aaacattcct
    31741 gtagatacaa ctattgagca aaagatgaat caccttaatg taggggagtt tgtcttattg
    31801 ctgcctgaac acctccgttc agaggaagaa cattataaat ctgtttttga agacgactta
    31861 accagtcgca tgtctagtca agatgaacga cagcaaatga ctgctacggt aggttattta
    31921 gaatcaggtc aggatcgttt tgtgtataat acgaccccta tttcttacca gcagtttttg
    31981 aaagatccaa tcatcattgt tataacaccc caatcaactg gtccacagtc cattttgttt
    32041 tggatagacg cagtacagaa ctacgttctc tttaatcaat tgtctgatgc ccaggagctt
    32101 atccagagac aaggcattga aaattgggtc tcagaaatgc aaacaggtta ccacaactac
    32161 atcacattat tggataatat ccagagggaa cgttgggtaa tgctagcagg agctgtgctt
    32221 gggattgcaa cttcaatctt gttgtttaac actatgaata ggctctactt tgaagaattt
    32281 agacgtgcca tttttatcaa acgcattgca ggtctcaggt tcttagaaat ccatcgcact
    32341 tatctctttg ctcaactggg tgtgttttta ctgggatttg ttgcgagtgt atttcttcag
    32401 gtagaggtag gagttgcttt cttagtcttg ttactcttta ctggtctatc tcttttacag
    32461 ttacatgtcc aaatgcagaa agaaaacaag atgtccatgc ttgttttgaa gggaggttaa
    32521 tatgattgaa cttaaacagg tgagtaaatc ttttggagaa cgagagttat tttcgaatct
    32581 ttcaatgaca tttgaggctg gaaaagtcta tgccttaatt ggttcaagtg gtagcggaaa
    32641 aacaaccttg atgaacatga ttgggaaatt agaaccttat gatgggacga ttttttaccg
    32701 aggtaaagac ttggccaatt ataaatcgag tgattttttc cgtcacgaat tgggctacct
    32761 cttccagaac tttggcttaa ttgaaaacca aagtattgaa gaaaacctta agctaggtct
    32821 cattggtcaa aagttgagtc ggtcggaaca gcggttgagg cagaagcagg ctttagaaca
    32881 ggtcggcctg gcttatcttg acctagataa gcgcatcttt gagttatcgg gcggagaatc
    32941 gcaacgagtt gccttggcaa aaattatctt aaagaatcca ccctttattc tggcagatga
    33001 gccaacagct tcaatagacc cagcaacctc tcagttgatt atggagattt tgctatctct
    33061 tcgagatgat aataggctaa tcattatcgc aacacataat ccggcaattt gggagatggc
    33121 tgatgaagtg ttcacgatgg atcatctgaa ataaaaatcc ttgtttttaa ttgcacgatg
    33181 agttactgaa atattatcat gaatcaataa ttggagttaa tttagaattg tactttatta
    33241 atattgaggt aactttttct tgataaagga ggaaatagtg gagaggaagt tagaatgaaa
    33301 aaattcgaca attatattat tgagaagcct tgcgattcta attcagataa actgcaaaaa
    33361 atcttaataa ttgaaaattt ggtagatgat attttgcaat ttcctctcag aatcaataat
    33421 agtgtaggag agattttcct cctacaaccg tttcaaaaga aaactatctt tattccatgt
    33481 tattttgagg aagatattgt gaaagtcaaa gatgatgata aagttgagtg gaatttgtta
    33541 gaatttcaaa aatttagagc atttttggct tagtaatctg tgttgaaggc tcaaaaccta
    33601 tggtaaaaaa gtcgctttga aaacgtattg cctccaaaga tttagttaaa taatgattta
    33661 acacaaaaag aaattattga agttctggaa agatgttgtt tcagtattga gaaaaggtgg
    33721 gaaaaacttg cgattttcac agagaaagga agaaaaagta tagaaatata gtcaattgaa
    33781 acaagaacag gacaaaagaa ccttttgtgc catatttttc tcctttcgct ttacaattgg
    33841 cttgaacacc tttattgtat cgcgtttgga gtttttttgg tataaccttc gacgcgcacc
    33901 cgcatagcgg gtgttttttt gtctcgcacc taacggagcg agacgaacta atagtcactt
    33961 aatcaaaaaa cgcaccatat caaaaactaa aaagtttgat atcatgcgtc atgtcttaaa
    34021 ctaattgact atactttcta ttcaaatgag cttttaacca attgattgag ccaatccact
    34081 cttaaaacca aagagcaatt tctcgcttag ctgactcttc tgaatctgaa ccatgtacaa
    34141 cattttggat aacctcattt tctccagcag cttttgcaaa gtcacctcga atagtgcctg
    34201 gtaaagcttc ttctggacga gttgcaccca tcatggtccg ccaagtttcg attactttgg
    34261 gaccagaaat gacacccaca agaactggac ctgaagtcat gaattcacga atcggtaggt
    34321 aaaaactctg accaaccaag tcctgatagt gctggtcaat caactcttct gaaacctgtg
    34381 aacgaaactc caatttttcg attgtaaatc cacgttgttc gatgcgcttt aacacttcac
    34441 ccactagccc tctttttaca ccatctggtt tgatgataaa gaatgtttgt tccatacccg
    34501 tctcctttgt cagcttcttt cttttatttt accacatttc gtggaaaaat ggagaaagtt
    34561 ttcagaagag agaatgagag aacccgaggg ttctctcatt ctctct
//
LOCUS       DAVEHY010000022        33346 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVEHY010000022 DAVEHY010000000
VERSION     DAVEHY010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.022"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            147..854
                     /locus_tag="VUZ44_001303"
     CDS             147..854
                     /locus_tag="VUZ44_001303"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU0320217.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            911..4636
                     /locus_tag="VUZ44_001304"
     CDS             911..4636
                     /locus_tag="VUZ44_001304"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU0320218.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            4729..6171
                     /locus_tag="VUZ44_001305"
     CDS             4729..6171
                     /locus_tag="VUZ44_001305"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU0320219.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNTASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            6208..7230
                     /locus_tag="VUZ44_001306"
     CDS             6208..7230
                     /locus_tag="VUZ44_001306"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU0320220.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKTLEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            7227..7772
                     /gene="purN"
                     /locus_tag="VUZ44_001307"
     CDS             7227..7772
                     /gene="purN"
                     /locus_tag="VUZ44_001307"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU0320221.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            7856..8365
                     /locus_tag="VUZ44_001308"
     CDS             7856..8365
                     /locus_tag="VUZ44_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU0320222.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEY
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            8390..9937
                     /gene="purH"
                     /locus_tag="VUZ44_001309"
     CDS             8390..9937
                     /gene="purH"
                     /locus_tag="VUZ44_001309"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU0320223.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLGSDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            10059..11321
                     /gene="purD"
                     /locus_tag="VUZ44_001310"
     CDS             10059..11321
                     /gene="purD"
                     /locus_tag="VUZ44_001310"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU0320224.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAADTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            11723..12211
                     /gene="purE"
                     /locus_tag="VUZ44_001311"
     CDS             11723..12211
                     /gene="purE"
                     /locus_tag="VUZ44_001311"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU0320225.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            12198..13289
                     /gene="purK"
                     /locus_tag="VUZ44_001312"
     CDS             12198..13289
                     /gene="purK"
                     /locus_tag="VUZ44_001312"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU0320226.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            13299..13526
                     /locus_tag="VUZ44_001313"
     CDS             13299..13526
                     /locus_tag="VUZ44_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU0320227.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            13589..14887
                     /gene="purB"
                     /locus_tag="VUZ44_001314"
     CDS             13589..14887
                     /gene="purB"
                     /locus_tag="VUZ44_001314"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU0320228.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(14942..18880)
                     /gene="strH"
                     /locus_tag="VUZ44_001315"
     CDS             complement(14942..18880)
                     /gene="strH"
                     /locus_tag="VUZ44_001315"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU0320229.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEKTPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYDSDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGSPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(19194..19910)
                     /locus_tag="VUZ44_001316"
     CDS             complement(19194..19910)
                     /locus_tag="VUZ44_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU0320230.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            20257..22044
                     /locus_tag="VUZ44_001317"
     CDS             20257..22044
                     /locus_tag="VUZ44_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU0320231.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            22041..22517
                     /locus_tag="VUZ44_001318"
     CDS             22041..22517
                     /locus_tag="VUZ44_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU0320232.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            22545..23450
                     /locus_tag="VUZ44_001319"
     CDS             22545..23450
                     /locus_tag="VUZ44_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU0320233.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVVVAAPSTPSESGEIEDDEF"
     gene            23437..24252
                     /locus_tag="VUZ44_001320"
     CDS             23437..24252
                     /locus_tag="VUZ44_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU0320234.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            24259..24663
                     /locus_tag="VUZ44_001321"
     CDS             24259..24663
                     /locus_tag="VUZ44_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU0320235.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            24958..26124
                     /locus_tag="VUZ44_001322"
     CDS             24958..26124
                     /locus_tag="VUZ44_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU0320236.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVSLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            26240..27277
                     /locus_tag="VUZ44_001323"
     CDS             26240..27277
                     /locus_tag="VUZ44_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU0320237.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            27484..28338
                     /locus_tag="VUZ44_001324"
     CDS             27484..28338
                     /locus_tag="VUZ44_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU0320238.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEAFAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            28488..28745
                     /locus_tag="VUZ44_001325"
     CDS             28488..28745
                     /locus_tag="VUZ44_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU0320239.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(29039..29131)
                     /locus_tag="VUZ44_001326"
                     /pseudo
     CDS             complement(29039..29131)
                     /locus_tag="VUZ44_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(29167..29463)
                     /locus_tag="VUZ44_001327"
                     /pseudo
     CDS             complement(29167..29463)
                     /locus_tag="VUZ44_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(29453..29614)
                     /locus_tag="VUZ44_001328"
     CDS             complement(29453..29614)
                     /locus_tag="VUZ44_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU0320240.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            29684..30448
                     /locus_tag="VUZ44_001329"
     CDS             29684..30448
                     /locus_tag="VUZ44_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU0320241.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(30688..30840)
                     /locus_tag="VUZ44_001330"
     CDS             complement(30688..30840)
                     /locus_tag="VUZ44_001330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320242.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            31058..32437
                     /locus_tag="VUZ44_001331"
     CDS             31058..32437
                     /locus_tag="VUZ44_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU0320243.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            32451..33116
                     /locus_tag="VUZ44_001332"
     CDS             32451..33116
                     /locus_tag="VUZ44_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU0320244.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
BASE COUNT         9109 a         6514 c         7784 g         9939 t
ORIGIN      
        1 aatttttaaa ctgtgagaaa gattcttctt gcagtttttt ctttacaatt tttggaaaac
       61 atctgctatt tattcggtta aattcttgta ttttttggtt ttttgtggta aaatgtgctc
      121 aagtaatacg aaaggcgaac tttaaaatgt caaaacaatt gatctattcg ggaaaagcta
      181 aagatatcta tacaactgag gatgaaaatc ttattatttc aacttacaag gaccaggcga
      241 ctgctttcaa cggtgtcaag aaggagcaga ttgcaggtaa gggagtcttg aataatcaga
      301 tttcatcttt tatttttgag aaattaaatg cggctggtgt ggcgactcac tttgtggaga
      361 aactttcaga cacggaacaa ctcaataaaa aggttaagat tattcctttg gaagtcgtgc
      421 tccgcaatta tactgctggt tccttttcaa aacgttttgg tgtggatgag ggaatcgcct
      481 tggagactcc gattgtcgaa ttttactaca aaaatgatga tttggatgat ccatttatca
      541 atgatgagca tgtgaaattc ctacagattg cggatgacca gcagattgcc tacttgaagg
      601 aagaaacgcg tcgtatcaat gaactattga aagtctggtt tgctgagatt gggcttaaat
      661 tgattgactt taagctagag ttcggttttg acaaggatgg caagattatc ttggcagacg
      721 aattttcacc agataactgc cgcttgtggg atgctgatgg caaccacatg gataaggatg
      781 ttttccgtag aggattggga gaactaaccg acgtttatga gattgtttgg gaaaagttgc
      841 agggtttaaa ataacaacct caaggctgtt tgggaatatt gcaagagctg aaataaagga
      901 ataagaattg atggataaac gtatttttgt tgaaaaaaag gctgattttc aggtcaagtc
      961 agagagtttg gttagagagc tccagcacaa cttgggactg tcaagcttga aaagtattcg
     1021 tattgtgcaa gtatatgatg tatttgactt ggttgaggac ttgtttgcac ctgcagagaa
     1081 gcacattttc tctgagcagg taaccgacca tgttttagat gaagtatctg tgcaggcgga
     1141 tcttgctaac tatgctttct ttgccattga aagtctacca gggcagtttg accagcgtgc
     1201 agcttcgtca caggaagcct tgcttttgtt gggaagttcg agtgacgtga cagtcaacac
     1261 agcccaactt tacttggtga ataaagatat tgatgcgact gagttggaag ctgtcaaaaa
     1321 ctacctgctc aatccagttg attctcgttt caaggatatc acgataggga ttgccaagca
     1381 ggagttttca gagtcagaca agaccattcc aaaattgcct ttctttgaaa gctatacagc
     1441 agaagacttt gctcgctaca aggccgaaca agggatggcc atggaagtgg atgatttgct
     1501 ctttatccaa gactacttta agtcaatcgg gcgcgtgcca actgagactg aactcaaggt
     1561 tttggacact tactggtctg accactgccg tcatacgact tttgagacag agttgaaaca
     1621 catcgacttt tcagcttcta aatttcaaaa gcaattgcag tcaacctatg acaagtatat
     1681 tgccatgcgc gaggaattag gtcggtctga aaaaccacaa accttgatgg atatggcgac
     1741 tattttcggt cgttatgagc gtgctaatgg acgattggat gatatggaag tctctgacga
     1801 aatcaatgcc tgctcagttg aaattgaagt ggacgttgat ggtgtcaagg aaccttggct
     1861 cctcatgttt aaaaacgaaa cccacaacca tccaacagaa attgagccat ttggtggagc
     1921 ggctacctgt atcggtggag ctattcgtga tccgttgtca ggccgttcct atgtttacca
     1981 agccatgcgt atttcaggtg ctggtgatat tacagcaccg atttcggaaa ctcgtgctgg
     2041 gaaattgcca caacaagtca tttctaaaac agcaactcat ggttattctt catatggtaa
     2101 ccagattggg cttgccacaa cctacgttcg tgaatacttc cacccaggct ttgtagctaa
     2161 acgtatggaa cttggtgccg ttgttggtgc ggctcccaag ggcaatgttg tccgtgaaaa
     2221 acctgaagca ggtgatgtga tcatccttct cggaggtaaa acaggtcgtg atggtgtcgg
     2281 tggtgcgacg ggctcttcta aggttcaaac agttgagtct gtagagactg ctggtgctga
     2341 ggttcaaaaa ggaaatgcca tcgaagaacg caagattcag cgcctcttcc gtaatggcaa
     2401 tgtcactcgt ctgatcaaga agtccaatga ctttggggca ggcggtgtct gtgtggctat
     2461 cggtgaattg gcagacggtc ttgaaatcga cctcaacaag gtgcctctta aataccaggg
     2521 cttgaatggt acagaaattg ccatctctga atcacaagaa cggatggcgg tcgtggttcg
     2581 tcctgaagat gtggatgcct tcgttgccga atgtaacaaa gaaaatattg atgctgttgt
     2641 ggtggcgaca gtaactgaaa aaccaaatct tgtcatgcac tggaatggtg agacaatcgt
     2701 tgacttggag cgtcgtttcc ttgacaccaa tggtgtgcgc gtggttgtcg atgccaaagt
     2761 tgtggacaag gatgtcaaac tcccagaaga gcgtcaaaca tctgctgaaa cactggaatc
     2821 agataccctt acggttctat ctgacctcaa ccatgcaagt caaaaaggat tacagactgt
     2881 ctttgactgc tctgttggac gctcaacggt taatcaccca cttggtggtc gttaccaact
     2941 cacaccaact gaggcatctg tgcagaaatt gccagttcaa cacggtgtga ctcatactgc
     3001 gtcggtcatt gctcaaggtt tcaacccata tgtagctgaa tggtctccat accacggtgc
     3061 tgcttacgcg gttatcgaag caactgctcg tttggtggct gctggtgcca actggtctaa
     3121 ggctcgtttc tcttaccaag aatatttcga gcggatggac aagcaagcag agcgttttgg
     3181 tcagccagta gccgcccttc taggctctat tgaagctcag attcaacttg gcttgccatc
     3241 tatcggtggt aaggactcca tgtctggtac ctttgaagaa ttgaccgttc cgccaacctt
     3301 ggttgccttt ggggtgacga cggcagatag ccgtaaggtg ctctctccag aatttaaagc
     3361 tgttggggaa aatatctact acatcccagg tcaagccctc tctgcagaga ttgattttga
     3421 cttgattaag aaaaattttg ctcagtttga agcaagccaa gctgaccata aagtgacatc
     3481 tgcatcagct gtcaaatacg gtggtgtagt tgaaagtttg gctcttgcta cctttggaaa
     3541 ctatattggt gcagaggtga ccttgcctga acttaaaaca gctttgacag ctcaattagg
     3601 cggctttgtc ttcacatctc ctgaagaaat tgctggagta gagaagattg gacaaacgaa
     3661 agcagacttt acactgactg tcaacggtgt gaagctagat ggacacaagc ttgacagtgc
     3721 atttcaaggg acattggaag aagtttaccc aacagaattt acccaagcga aagaactaga
     3781 agaagtacca gctgtggcat cagatgttgt gattaaagcc aaagaaaagg ttgaaaaacc
     3841 tgtggtttac atcccagtct ttccaggaac caactcagaa tatgattcag ctaaggcctt
     3901 cgaaaaagaa ggtgcagagg tcaatttggt gccattcgtg accttgaatg aagaagctat
     3961 tgtcaagtca gttgaaacta tggttgacaa tatcgacaag actaatattc tcttctttgc
     4021 cggtggattc tcggctgcgg atgaaccaga tggttcagct aagtttatcg tcaatatcct
     4081 gcttaatgaa aaagtgcgtg tggctattga tagctttatc gcccgtggtg gcttgattat
     4141 cggtatttgt aatggattcc aagccttagt caaatcgggt ctcctaccat acggaaactt
     4201 tgaagatgct aacagtacta gtccaaccct cttctacaat gatgccaacc aacacgtggc
     4261 caagatggtg gaaactcgca ttgccaatac caactcacca tggttggctg gtgtgcaagt
     4321 gggcgatatc cacgctattc ctgtttcgca cggtgaaggg aagtttgtcg tgacggctga
     4381 ggaatttgca gagctccgtg acaatggaca aattttcagc caatacgttg actttaacgg
     4441 taaaccaagt atggattcta agtacaatcc gaatggttct gtccatgcca tcgaaggaat
     4501 taccagcaag aatggtcaaa tcatcggtaa gatgggccac tcagaacgtt atgaggatgg
     4561 tcttttccaa aatatcccag gcaataaaga ccaacacctg ttcgcatcag cggttaaaca
     4621 tttcactgga aaataagact tacagatttt ctaatagata gtatcagtaa tgtaaaagtc
     4681 atgtaaatct agctcttgat gattacaaat gaaaattagg tataaaaaat gacatacgaa
     4741 gtaaaatctc ttaatgaaga atgtggtgtt ttcggtattt ggggacatcc agatgctgct
     4801 aagttgacct attttggact ccacagtctt caacaccgtg gtcaggaggg ggcaggaatc
     4861 ctctccaacg atcaaggaca actgaagcgc catcgtgaca tggggctttt atcagaagtt
     4921 ttcagaaatc cagctaattt ggataaattg acaggagctg gtgcgattgg gcatgtgcgt
     4981 tatgcgactg ctggcgaagc ttctgtagat aacatccagc ccttcctctt ccgttttcac
     5041 gatatgcagt ttggcttggc tcataatgga aatctgacca atacagcctc tctcaagaaa
     5101 gaactggaac aaagaggagc aattttcagc gcgacttcgg actctgaaat cttggctcac
     5161 ctcattcgtc gcagtcataa tcctagcctg atgggcaaaa tcaaggaagc gctcagcctt
     5221 gtcaaaggtg gttttgccta tatcttgctg tttgaggaca agttgattgc ggctcttgac
     5281 cctaatggct ttcgtccgct ttctatcggg aaaatggcca acggagcggt ggttgtttcc
     5341 tctgaaacct gtgcttttga ggtcattggt gccgagtgga ttcgtgattt gaagccaggt
     5401 gagattgtga tcattgatga cgagggcatt cagtatgaca gctatacaga tgatacccag
     5461 ttggcgattt gttctatgga gtatatctac tttgcccgcc ctgattctaa tatccacggt
     5521 gtcaatgtcc atacggcacg taagagaatg ggagcgcaat tggcgcgaga atttaagcat
     5581 gaggcagata ttgtagttgg tgtgcccaat tcttccctaa gcgcggctat gggatttgcg
     5641 gaagaatcag gcttaccaaa tgaaatgggt ctgatcaaaa accaatacac ccagcgaact
     5701 tttatccaac cgactcaaga attgcgggag caaggagtgc ggatgaaact gtctgctgtt
     5761 tcgggtgttg tcaaaggcaa acgtgtggtc atggtggatg attccattgt acgtggaaca
     5821 acctctcgtc gtatcgttca gctcttgaaa gaagcgggtg cgactgaggt tcacgttgcc
     5881 attggaagtc ctgcactagc gtatccatgt ttctacggga ttgatatcca gacccgtcag
     5941 gagctgattg cagccaatca tacggtcgaa gaaactcgcc aaatcattgg tgcggacagt
     6001 ctgacttatc tttcaattga tggcttgatt gagtcgattg gtatcgaaac agatgcgccg
     6061 aacggtggtc tctgtgtcgc ttactttgac ggtgactacc caacgcctct ttatgactac
     6121 gaagaagact atcgtagaag tttggaagaa aagaccagtt tttacaagta ggcgacagat
     6181 tctccattaa agaaaaggaa aaaacaaatg acaaataaaa atgcatatgc ccagtcgggt
     6241 gtggatgttg aagcgggtta tgaagttgtt gaacggatta aaaagcacgt ggcccgtacg
     6301 gagcgtgcag gtgtcatggg agctcttggt ggctttggtg gtatgtttga cctttccaag
     6361 actggggtta aagaacccgt cttgatttca gggactgacg gtgtcggaac caagctcatg
     6421 ttggctatca agtacgacaa gcacgatacc atcgggcagg actgtgtggc catgtgtgtc
     6481 aacgacatca ttgctgcagg tgcggaaccc ctctattttc tcgactacgt agcgacaggg
     6541 aagaatgaac cagctaagct agaacaagtg gttgctggtg tggcagaagg ttgtgtgcag
     6601 gctggtgctg ccctcatcgg tggggaaacg gctgaaatgc cgggcatgta cggcgaagac
     6661 gactatgact tggctggttt tgcggtcggt gtggctgaaa aatctcaaat cattgacggt
     6721 tcaaaggtgg tagagggaga tgttcttctc ggacttgctt caagtgggat tcactcaaat
     6781 ggttactctt tggttcgtcg tgtctttgcg gattacacag gtgaggaagt cctaccagaa
     6841 ttggaaggca agaaacttaa ggaagttcta cttgagccga ctcgtatcta tgtcaaggct
     6901 gtcttgccgc tcatcaaaga agagttggtc aacggcattg cccacatcac aggtggtggc
     6961 tttatcgaaa atgtccctcg tatgtttgca gatgacctag ctgctgaaat tgatgaaagt
     7021 aaagttccag tgcttccaat tttcaaaacc cttgaaaaat acggtcagat taaacacgaa
     7081 gaaatgtttg aaatcttcaa tatgggtgtg ggactcatgt tggcggtcag ccctgaaaat
     7141 gtagagcgtg taaaagaatt gttggatgaa gcagtctatg aaattggtcg catcgtcaag
     7201 aaagaaaacg aaagtgtcat tatcaaatga aaaaaatagc ggtttttgcc tctggtaatg
     7261 gctcaaattt tcaggtgatt gccgaagaat ttccagtgga gtttgtcttt tcagaccatc
     7321 gtgatgccta tgtgcttgag cgtgcaaagc agctcggcgt tctgtcctat gcttttgaac
     7381 tcaaggagtt tgagagcaag gcagactacg aagcagccct tgtcgaactc ttggaagaac
     7441 accagattga cttggtttgc ctagcaggct acatgaaaat cgttggacca accttattgt
     7501 cggcttatga aggtcggatt gtcaacattc atccagccta cttgccagaa tttccaggag
     7561 ctcatgggat tgaggatgct tggaatgctg gcgtgggtca gtctggtgtg accattcact
     7621 gggtggattc gggtgtggat acaggccagg tcatcaaaca ggttcgtgtg ccacgactag
     7681 ctgatgatac cattgacaga tttgaagctc gcatccatga agcagagtac aggttgtatc
     7741 cggaagtagt gaaggctcta tttacagatt gactttttga tgattcatat gatatctttg
     7801 attttaaatt ggagtcagtg tttgttgaag acggcttcaa acggaggtat ttgtaatgtt
     7861 agaatctaaa aaaacaactc gatatgtatt ttatgtctat ctgatgttat taacttgggg
     7921 aatcttattt aagtttgaaa caaatcctga atttatagca tttttcttag ctccaaggta
     7981 tatcaattgg attccatttt cagaaccact aatagtcgat ggaaaaattg tttttgctga
     8041 aatgttattt aatctgattt tctttattcc attaggtgtt tgtttccctt tgataaaaac
     8101 taatttatct agtttaagaa tagtcgggac aggtttcttg attagtttat tgtttgagta
     8161 cttacagtat attttagcaa taggtataac agatataacg gatttgactt taaatacgct
     8221 aggtgtctgt gtaggcttac tgatttatca aatttttata agagtgttca aatcacagac
     8281 tagaaaatgg atcaatatct taggtatgct tagccttggt tttgcttatc ttgttttact
     8341 gttactgcat ttaattggtg tttaactaat gattaaaaag gagaatataa tgactaaacg
     8401 cgtcttaatc agcgtctcag acaaagcggg cattgttgaa tttgcccaag aactcaaaaa
     8461 acttggttgg gagattatct caacaggtgg aactaaggtt gcccttgata atgctggggt
     8521 ggataccatt gctatcgatg atgtaactgg tttcccagaa atgatggacg gtcgtgtgaa
     8581 gaccctccac ccaaatatcc acggagggct tctcgctcgt cgtgacttgg atagccactt
     8641 ggaagcggct aaggacaaca agattgagct cattgacctt gtggtggtca acctttaccc
     8701 atttaaggaa actatcctta aaccagatgt gacttatgct gatgcagttg aaaatatcga
     8761 tattggtggg ccgtctatgc ttcgttcagc agcgaaaaat catgccagtg ttacagttgt
     8821 ggtagatcct gctgactacg ctgtggtttt ggacgaattg gcagcaaacg gcgaaacctc
     8881 ttatgaaact cgccaacgtt tagcagccaa agtatttcgt cacacagcgg cttatgacgc
     8941 cttgattgca gaatacttca cagctcaagt gggtgaaagc aagcctgaaa aactcacttt
     9001 gacttatgac ctcaagcaac caatgcgtta cggtgagaat cctcaacaag acgcggactt
     9061 ttaccagaaa gctttgccta cagattactc tattgcttca gccaaacagc tcaacgggaa
     9121 agaattgtca tttaataata tccgtgatgc agatgctgct atccgtatca tccgtgactt
     9181 caaagatagt ccaaccgttg tggctctcaa acacatgaat ccatgtggaa ttggtcaagc
     9241 tgatgacatc gagactgctt gggactacgc ttatgagtct gacccagtat ctatctttgg
     9301 tgggattgtc gtcctcaacc gtgaggtgga tgctgcgaca gctgagaaga tgcacggcgt
     9361 tttcctcgaa atcatcattg caccaagcta tacggatgaa gcgctagcca ttttgatcaa
     9421 taaaaagaaa aacttgcgta tccttgcctt gccatttaat gctcaagagg ctagcgaagt
     9481 ggaagcagaa tacacaggtg tagtcggtgg acttctcgtg caaaatcaag acgtggtcaa
     9541 ggaaagccca gctgactggc aagtggtgac caaacgtcag ccaactgaga cagaagcgac
     9601 tgctcttgag ttcgcttgga aggctatcaa gtacgtcaaa tcaaatggta ttatcgtgac
     9661 caacgaccac atgacacttg gtgttggtcc aggtcaaacc aaccgtgtgg cttctgttcg
     9721 ccttgccatt gaccaagcca aagatcgtct gaacggggcg gtccttggtt cagatgcctt
     9781 cttcccattt gcggataacg tggaagaaat cgccaaagca ggaattaagg ccatcatcca
     9841 gcccggtggc tctgtccgtg accaagaatc catcgaagca gcggataaat acggcttgac
     9901 tatggtcttt acaggtgtga gacattttag acattaagaa gataaaaggg aagaaaacag
     9961 tttctttcct tttttggctt aaaatgctaa ctgaaacaag attaaaacga acttttttga
    10021 tataatgttg gtaaataatt cgcaaaagag gttgaggaat gaaactgctt gttgtcggtt
    10081 ctggtggtcg tgagcatgcg attgctaaaa agttacttga atcaaaagac gtggaaaaag
    10141 tctttgtagc tcctgggaat gacggtatga ctctggatgg tctggaattg gtaaatatat
    10201 ctatttccga acattataaa ttgattgact tcgcaaaggc caacgatatt gcttggacct
    10261 ttatcggtcc agatgacgcc cttgcggctg gtatcgtgga tgatttccat gcagctggtc
    10321 tcaaagcctt tggtccgaca agattggcag cggagctgga gtggtccaag gatttcgcca
    10381 aggaaatcat ggtcaaatat ggtgtttcga cagcagccta tggcacattt tcagatttcg
    10441 aggaagcaaa ggcctatatc gaaaagcatg gtgcgcctat cgtagtcaag gcggatggct
    10501 tggcgcttgg gaagggtgtc gtcgttgctg agacggttga gcaagcggtc gaagccgctc
    10561 atgagatgct tttggacaat aaatttggtg actcaggtgc gcgcgtggtt attgaggaat
    10621 tccttgaagg agaggaattt tcactctttg cctttgtcaa tggtgataag ttctacatca
    10681 tgccaacggc tcaggaccac aaacgtgcct acgatggcga caaagggcct aacacgggtg
    10741 gtatgggtgc ctatgcgcca gttccacact taccacagag tgtagttgat acagcggctg
    10801 acaccattgt caagccagtt ctagaaggga tgattaaaga aggtcgccct tatctgggag
    10861 ttctttacgc agggcttatc ctgacagctg atggaccgaa agtcattgag ttcaacgctc
    10921 ggttcggaga tccagaaact cagattatct tgcctcgctt gacctctgac tttgctcaaa
    10981 atatcacaga tatcctggat agcaaggagc caaatatcat gtggacggac aagggtgtga
    11041 ctctgggtgt ggttgtcgca tccaagggct acccgctaga ctatgaaagg ggcgttgagt
    11101 tgccagccaa gacagaaggc gatgtcatca cctactatgc aggggctaag tttgcggaaa
    11161 atagcagagc actgctctca aacggcggac gagtttatat gctcgttacc acagcagata
    11221 ccgtcaaaga agcccaagcc agcatctacc aagaactata ccaacaaaaa atagaaggac
    11281 tcttctaccg aacagatatc ggaagcaagg caattaagta aagatataag aataacgcgc
    11341 cgtagtcgcc aaacacgata atggtcgtcg tggtgaaaag accagaacag tgaatgttct
    11401 ggtcagggga aacttggaga ccttaggctc aaagtttagg aatgaaaccg aaggtttgct
    11461 tccgcctcca tcacctaaga ccattatcaa aaagaaaaat aaaaattcac aaaatacgtt
    11521 aatgatcgta tggtttgcga gcgttagcga gctaatatag aacaatcacc gccgttgtga
    11581 aagaacgatt ggatgataat ccaatcgttc agggaaattg gaagaccttg ggtttccaat
    11641 ttaggcatga gacacctttg gtggctgctg ccgtccctca caagctaagg tgattgttga
    11701 aaaagaggaa aaaggagaag aaatgaaacc agtaatttcc atcatcatgg gctcaaaatc
    11761 cgactgggca accatgcaaa aaacagcaga agttctagac cgcttcggtg tagcctacga
    11821 aaagaaagtt gtttccgcac accgtacacc agacctcatg ttcaaacatg cagaagaagc
    11881 atatagccgt ggtattaagg tcatcatcgc aggtgctgga ggcgcagccc acttgccagg
    11941 aatggtagct gccaaaacaa cccttcctgt cataggggta cctgtcaagt ctcgtgctct
    12001 tagtggagtg gattcactct attctatcgt tcagatgccg ggtggggtgc ctgttgcgac
    12061 catggctatc ggtgaagctg gagcgactaa cgcagctctc tttgccctcc gtctcctctc
    12121 tgtagaagat aagtccattg cggatgcact tgccaacttt gctgaagaac aaggaaaaat
    12181 cgcagaggag tcgtcaaatg agctcatcta aaacaatcgg aattatcggt ggcggtcaac
    12241 tgggtcagat gatggccatt tctgctatct acatgggcca caaggttatc gcgctggatc
    12301 ctgcggcgga ttgcccggtc tctcgtgtgg cggaaatcat tgtggcacct tataacgatg
    12361 tagacgccct ccgtcagttg gcagaccgtt gcgatgtcct cacttacgag tttgaaaatg
    12421 tcgacgctga cggtttggat gccgttatca aggatggaca actccctcaa gggacagacc
    12481 tgctccgcat ttcgcaaaat cgtatttttg aaaaggactt tttgtcaaac aaggctcaag
    12541 tcactgtggc accctacaag gtcgtgactt ctagcctaga cttggcagat atcgacttgt
    12601 cgaaaaacta tgtcctcaag actgcgactg gtggctacga tggtcatgga caaaaggtta
    12661 ttcgttcaga agtagacttg gaagcagcct atgcgctagc agaatcagca gactgcgtct
    12721 tggaagaatt tgtcaacttt gcccttgaga tttctgtcat cgtgtcagga aatggcaagg
    12781 aggtgacgtt tttcccagtt caggaaaata tccaccgcaa caatatcctg tctaagacca
    12841 tcgtaccagc ccgcatttct gaaagtctag tagacaaggc taaagctatg gcagtgcgaa
    12901 tcgcagaaca actcaacttg tctggaactc tctgtgtgga aatgtttgcg actgatgatg
    12961 acgttattgt caatgaaatc gccccacgac cacataactc tgggcactat tctattgaag
    13021 cctgtgattt ctctcagttt gacacccata ttctcggtgt tctcggagca ccattaccag
    13081 tcatcaaact ccatgcgcca gccgttatgc tcaatgtcct aggtcaacac gtcgaggctg
    13141 ctgaaaagta tgtcgcagaa aatccaagcg cccacctcca catgtatggt aaaatagaag
    13201 caaagcataa tcgtaagatg ggacatgtga ccttgtttag tgatgtaccg gatagtgtgg
    13261 atgagcttgg ggaagggatt gatttttagg acaagtctat gatacaaatt atcgttaata
    13321 catttattga aaaggataag actggagcag ttgttgaagt gttgtatgcc agtgctgacc
    13381 aagataaggt acaagctaaa tatgaagaac tagctgcaca ataccccgaa aattatttag
    13441 ctatctatga tgtaccgctg gatacggatt tgaatacact agatcattac ccgtctgtgt
    13501 ttattgaaaa agaggagttt gagtagaaat cttggtttac ctagatagct tattcccaac
    13561 agcttaagaa gaaaggaaaa attaacacat gatcaaccgt tactctcgcc ctgagatggc
    13621 gaatatttgg agtgaagaaa ataaataccg tgcttggctt gaggtggaaa tcctctctga
    13681 cgaggcatgg gctgagttgg gggaaatccc taaggaagat gtggctttga ttcgcaagaa
    13741 ggcggacttt gacatcgacc gtattttgga aattgagcag gagacgcgcc acgatgtggt
    13801 ggctttcacg cgtgcggttt ctgagactct tggtgaagag cgcaagtggg ttcactatgg
    13861 gttaacttct accgacgtgg tggatactgc ttatggttac ctctacaagc aggccaacga
    13921 catcatccgt cgtgaccttg aaaacttcac taatatcatc gctgacaagg ccaaggagca
    13981 caagttcacc atcatgatgg ggcgtactca tggtgtgcac gctgagccga caacctttgg
    14041 tcttaaattg gcaacttggt acagcgaaat gaaacgcaat atcgagcgtt tcgagcatgc
    14101 agctgctggt gtagaagctg gtaagatttc tggtgcggtt gggaactttg ccaatatccc
    14161 accatttgta gaggagtatg tctgcgataa acttggcatc cgtgcccaag aaatctctac
    14221 acaagtcctt cctcgtgacc ttcacgctga gtactttgcg gttcttgcca gcattgcgac
    14281 ttcaatcgaa cgtatggcga ctgagattcg tggtctacaa aaatctgagc aacgcgaagt
    14341 agaagagttc tttgctaaag ggcaaaaagg gtcttcagca atgcctcaca aacgcaaccc
    14401 aatcggttct gaaaatatga ctggtctggc gcgtgtcatt cgtggtcaca tgattacggc
    14461 ttatgaaaac gtcgctctct ggcacgaacg cgatatttct cactcatcag ctgagcgtat
    14521 catcacacca gatacgacca ttttgattga ctacatgctc aaccgttttg gaaatatcgt
    14581 caagaacttg acagtcttcc cagaaaatat gatccgaaac atgaactcga cttttggtct
    14641 tatctttagc caacgggcta tgttgacatt gattgaaaaa ggcatgaccc gtgagcaagc
    14701 ctatgacttg gtgcaaccaa aaacagccta ctcttgggac aaccaagtag actttaaacc
    14761 acttcttgag gcagattcag aagtaacatc acgtctcact caagaagaaa tcgatgaaat
    14821 cttcaaccca gtttattaca ccaaacgagt ggatgatatc tttgaacgtc ttggactagg
    14881 tgattaatta aaaaataaac agcgagcttc aatctcgctg tttatttttt atcgaaaaga
    14941 cttagtcttc ttttctttta gtgagtccat aggctgctag tgtggacatg agtcctgcga
    15001 ctactagtcc tgcagaatcg tgagttcctg tttcaggaag ttttttctct gttaccacag
    15061 gagctggatc ttgaggaaga gctttgcttt cctcagcagg agcagttgat ggagctggtt
    15121 ggcttgggat ttctagtttt ggtttttctt cagcaatagc ggcttgtccg ttttcatcgc
    15181 ctacatgtgt taccatagtt ccgacttcga ctatttgagt aacggcttcc tgtgctacga
    15241 cactatttac aagtgttttc acttccttac catcggcaga agtgctcaca gagtagaagt
    15301 tgctacgatg tccattgacg cccttagtaa tgacttgtgt ttttcctttg agtaagagtg
    15361 gattttcacg agtcactgtg gtaaatggaa tttcttcttc ttggatatcc agtctaggtt
    15421 ttacctcagt agttggtgca agaccacttt catcaccctt gtgagttaca ggagagccaa
    15481 cttcaaccac ttggtttata acttctttgg ttacctggct atcaaggact gtttctgttg
    15541 tttttccatt ttcagtgagt acagagatgt aatgagttcg ttcacctttg actcctgctg
    15601 tgataatatt ttcctgacca gctgggaggt taggattttc tttcttgata acttcaaatg
    15661 gaatttcttc agttcttgtg atgagttctg gtctggtttc aacattggca gccacttcat
    15721 tttcatctag gcttcctgaa tgagttgcag ctggtttgag gccttgaaga gcggctttta
    15781 ggttggctac aagtgtgtca agctcagctt gtttattacg gttgaggttg taatttagag
    15841 ctgttttagc tgcgtcaagg gcctcaagac tttctttact atatccttct aagtttgtag
    15901 gaattttagc taattcttcg cggagagcat tataattagc acggaagtag tctttgttgt
    15961 ggtctgcaaa ggcagtcatg agttcaaaga tttcctcttc cttgtactca gcgcttggtc
    16021 tatctgccca gattgaaagc atacttccga ctgttggaag atctacttca ggatatttgg
    16081 tagaagctag ttgattgaat ggaactttac cagaattttc aactgctttt gaaagagggt
    16141 aagcttcatc ttgtttgtga ttgcctataa cataatacca gtcaccgttg gtattcaaga
    16201 atttatagcc tttgcttgct aggtattgag gtgatgcgag gttatatccc caccagcctt
    16261 tagaccagta agaaatcaag acatctttgt caaactgaac atcgtccttg tcttcatagt
    16321 agaagccatc gttgaaggcc attggttgaa gccctctttc tttggccata gctgcgaggg
    16381 tgttggcata ttcggcaaat ttgccataga gttgatacca cttgaggtag taccagcctt
    16441 gggcactagt cgcatcgttg gcgtattcgt cagtaccaaa gttgaaaatc tttgttttac
    16501 ctgcaaagaa gtccatgtat ttaccgatga gggcttttac aaagttcatc gcttcttcgt
    16561 ttttcaagtc catagttgtt tttgaaactt tatcaaagtg ggcttgagga tttttaatac
    16621 ctaatttttc catggcaacc agcatagcat ccatgtgacc tggactgtta atagctggga
    16681 tgagaccaat gtccttagat ttagcgtatt caattagctc tgtcacttct gcctgtgtta
    16741 gtgcagtacc gtttggatcg tcgtagtaag ctttagttcc ttcgataata gcttttttaa
    16801 cgtcatcact agcataggtt tttccgttgg cagtaatggt catatcattg agtagaaagc
    16861 gaagtccgtc atttcctaga aggagatgga catcagaata tccgagctca ctggccttgt
    16921 ctacgatgcg tttgagctgg tccagagtaa agtatttgcg tccagcatcg attgagatta
    16981 ccttgttttt ggcaagtttt tcaacctcac gtttagcttc ttcttctttt tgagcttcag
    17041 gcgtgagggt caagttgttg acagtttctt gaagtttagc aatggcttga tcaatcgtat
    17101 cttgttgggc acggctaagg ttgctatcga gagagcgaat agctttttca gcttctttta
    17161 cggccgcgac gctttctgca gtataacggt tcaggtcttt tggtacctcg ttaagtgctt
    17221 gctctgcaga ttcataatca gctgcgaagt attcagcgtt ggcatttgca aaatgacgca
    17281 tgagtttgaa gaggtgtgat ggtgaataac gtgcagatgg agtgtcagcc caagcagcta
    17341 ccataccacc gatgattggg atatcagctc cttctgtttt tggtacagaa gtgattggtg
    17401 tgtttttaat accattgagc ccctgatcga gattgtacca gccttggcca tcagcgtttc
    17461 gtccaagaac gtagtaccaa gcatcattgg tattaaggat ttggtgacct ttttcagcta
    17521 gtagtttaga agaagcgaca tcgtagcctc cccaaccacc agtccacata gaaacgatga
    17581 tgtctttgtc aaaactacca aagcttgtgt cgctattgta gtagataccg tcgttaaagg
    17641 ccattggttt gagaccgtgc gattttacaa tacgagcgag gtcattggcg taggcaataa
    17701 atttttcata gccttttaca gggtagcctt cgtttggata gtatttatca gcttgaagca
    17761 cactccaacc tttagcatct gtcgcatcat tggcatattc atcaagtccg atgttgaaga
    17821 tttcagtctt tttcgcgaaa taagcagcat acttgtcgat aagggctttt gtaaaagcga
    17881 cagcttgttc gttgtcaaga tcgacagtac gggctgattt cttcccaaaa tagctaaagt
    17941 tagggttttg gattcccaat tctttcatgg cattgagaat cgcatccatg tgtccaggac
    18001 tatttactgt cggaatgaga ccgatacctt tatctttggc atagttaatc agatctgtca
    18061 tttgactttc tgttaagtga ttgccgtttg gatcgttgta ataatcattt gtaccttttt
    18121 caatggcgcg tttgacatcg tcactgtcat aggtcttgcc gttagctgtg atgctcatat
    18181 cgtccaacat gaaacggagt ccatcatttc cgactaatag gtgtaaatca gtgtagccat
    18241 aatgtttcgc tttatcgatg atttccttga gctgttctgg tgagaaatat ttacgtccag
    18301 catcaataga aacaattttc tttttcgcta gtttttcatt tacagttgca gcacgttcct
    18361 ttcctgcctc tgtttccggt ttgtcagcct ctgctttcgc ttcatctttt ttagctggtt
    18421 tatctttgtc agtcttgtcc gtatttgact ctttagaatc aacctctttc gcttcttcct
    18481 ttttagggct agcttcttct gcctttttat tagcagtttc tttttcagca gaagttggag
    18541 ttaccacttc tgctttatca ctaggagttg aactaacttc ctcttgtggt ttttcttctg
    18601 tttttggaag actagctacc ttatcagtag ctggagtttc tgtttctaca gtttttggag
    18661 cttctggttg aagctctgct ttaggtgttt tctcagtccg attttcggat gattgagggg
    18721 aatcagaaac cgtatggatg gtcggttggt tttctgtagt agtaggagta actccatcgg
    18781 ctgcaacagt ctgtgcttgg aaggcaaatc caattagaac agaagctgct cctacagcgt
    18841 atttacgaat agaaaaacgc tgttgttttt catgtttcat tgcaaaacct cctgattgca
    18901 ttgttatatt gatagcgatt atataaatca acgcctttat tttatttctt atattaacga
    18961 gagtcaagag gagatgacaa aaaactataa taagtataaa aaaatataaa atttaaactt
    19021 aagatttcag attggtcgaa aaatacatat atatatctag tataattttt ggttctattt
    19081 ctataaaata ttccacaaat tatagaatct tccaaaaata ggtaagcgct acctttttgg
    19141 tgtggtataa taagcataga aaaagcccga gcgattaggc tcaggctttc ttcttagtga
    19201 tcacggtcac atgagatgaa tttaatcttg tagtaatcag atcgtttgta agtttcactg
    19261 tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag gacagtaggg
    19321 aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa gactatttcg
    19381 ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt gaaacgatta
    19441 tagatagaac tatagtattc aaggtttgga taatttgcgt tgatatattg ttctgggatg
    19501 taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc aatcttgtag
    19561 tagaattgat cgccgcgtag acccaatttt tccaagtaaa caagcttgtt tccgcgttca
    19621 attgaaagaa cagttacctt atcatcttta gcattgaaga gctcaatatc tgaaaactct
    19681 acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg gcggacaata
    19741 tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct gacatcgtac
    19801 attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg cccagagatg
    19861 attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat atttttacct
    19921 ctattttcct tctccataga aaattttacc ataaaagcga aaaaaatagt agtcttttga
    19981 ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct catattttat
    20041 caatgtattc tatacaaaat tattttaggt cctatattcc gaatttaaag agcgtttgaa
    20101 atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa atgcagtaaa
    20161 tatcccgaca tttctattga caattcaaac agattggttt ataattaata taacaacaaa
    20221 tgaaagcgca aactttcgcg gtcggaaggt agttttatga cacgatttga gatacgagat
    20281 gatttctatc tcgatggaaa atcatttaag attttatctg gtgccattca ttattttagg
    20341 gttcctccag aggattggta tcattcgctc tataacttga aggctcttgg ttttaatacg
    20401 gtagagactt atgttgcttg gaatttacac gagcctcgtg aaggtgagtt tcattttgac
    20461 ggtgatctgg atttagagaa atttctccaa atagcgcagg atttgggtct ctacgcaatt
    20521 gtgcgtccgt ctccatttat ctgtgcggaa tgggaattcg gtggcttacc agcttggctc
    20581 ttgaccaaga acatgcgaat tcgctcatcc gacccagcat atatcgaggc agttggtcgc
    20641 tactatgatc agttattgcc aagactggtg cctcgtttgt tgaacaatgg tggcaatatt
    20701 ctcatgatgc aggttgaaaa tgagtatggt tcttacggag aagataaggc ttacctgaga
    20761 gcgattcgac agctaatgga agagtgtggt gtaacctgtc ccctctttac atcagatggt
    20821 ccatggcgag ctactctgaa agctggaacc ttaattgaag aggacctctt tgtaacagga
    20881 aactttggtt ctaaggcacc ttacaacttt tcgcagatgc aggaattctt tgatgaacat
    20941 ggtaagaaat ggccactcat gtgtatggag ttctgggatg gttggttcaa tcgctggaaa
    21001 gaaccgatta tcacacggga tcctaaggaa ttggcagatg cagttcgaga ggttttggaa
    21061 caaggctcta tcaatcttta catgttccac ggtggtacaa actttggttt catgaatggt
    21121 tgctcagctc gaggaacttt ggacctgcca caagttacat cttatgatta cgatgccctt
    21181 ctggatgaag aaggaaatcc aactgctaaa tatcttgcag tcaagaagat gatggcaaca
    21241 catttttcag agtatccgca gttggaacca ctctacaaag agagtatgga gttggatgct
    21301 attccactag ttgaaaaagt ttctttgttt gaaaccttag atagcttgtc aagtcctgta
    21361 gaaagtctct atcctcaaaa gatggaggag ctgggacaaa gttatggcta cctactttat
    21421 cgaacagaaa caaactggga tgcagaagaa gaaagacttc gtatcattga tggtcgagat
    21481 agggcccagc tgtatgtcga tggtcagtgg gttaaaactc aatatcagac agagattggg
    21541 gaagatattt tttatcaagg taaaaagaaa gggctatcta ggttagatat cttgatagaa
    21601 aatatggggc gtgtcaacta tgggcataag ttcttagcgg atacgcaacg taagggaatt
    21661 cggacagggg tctgtaagga tctgcatttc ttactaaact ggaaacacta tccactccca
    21721 ctagacaatc ctgagaaaat tgatttttca aaaggatgga ctcaaggaca accagccttt
    21781 tacgcttatg actttacagt cgaagagcca aaagatactt acctagactt gtctgagttt
    21841 ggtaagggag ttgcctttgt caatgggcag aatctaggac gtttttggaa cgttggccca
    21901 actctctcac tttatatccc tcatagctat ctcaaggaag gtgccaaccg tatcattatc
    21961 tttgaaacag aaggtcaata taaagaagag attcatttaa ctcgtaaacc tacactaaaa
    22021 catataaagg gggaaaactt atgacaattg taggatgccg tattgatgga cgtttgatcc
    22081 acggacaagt agccaatctt tgggctggaa aactaaatgt ttcacgcatt atggttgtag
    22141 acgacgaagt tgtcaacaac gatattgaaa agagtggttt gaaacttgcg acaccaccag
    22201 gtgtgaaatt gagtattttg ccagttgaga aagctgcagc caatattctt gctggtaaat
    22261 acgatagcca acgtctcttt atcgtggctc gtaaaccaga ccgcttcctt ggtttggtag
    22321 aagcaggtgt accacttgaa acccttaatg ttgggaatat gtctcaaaca ccagaaactc
    22381 gttctattac acgttctatc aacgtagtag acaaggatgt ggaagacttc cacaaactgg
    22441 cagaaaaagg tgttaaactt actgctcaga tggttccaaa tgatccaatt tcagactttt
    22501 tgagcttatt aaaataggaa aaaaattttt aggaggtcat tgttatgata caatggtggc
    22561 aaattttact tctcactttg tactcagctt atcaaatctg tgatgagttg acgatcgttt
    22621 catctgcagg ttctcctgta tttgctggtt tcattactgg tttaatcatg ggagatgtga
    22681 ctactggttt acttatcggt ggtaacttgc aactgttcgt tcttggggtt ggtaccttcg
    22741 gtggtgcttc tcgtatcgac gcaacttctg gtgcggttct tgcgacagcc ttctctgttt
    22801 cacaaggaat tgatgcaccg cttgccatta ctacaatcgc tgtaccagta gcagctctct
    22861 tgacttactt cgacgttctt ggtcgtatga ctactacctt cttcgctcac cgtgtggatg
    22921 ctgcaatcga acgctttgac tataaaggta ttgaacgcaa ctacttgctt ggtgcgattc
    22981 cgtgggctct atctcgtgcc cttccagtct tctttgccct tgcttttggt ggtgcctttg
    23041 tacaatcagt agtagacttc gttgaagcct acaaatgggt tgcagatggc ttgacactcg
    23101 caggacgtat gcttccaggt cttggatttg caatcttgct tcgttacctt ccagttaaac
    23161 gtaaccttca ctaccttgct atgggatttg gtttgacagc tatgttgact gttctttact
    23221 catatgtaac aggtcttggt ggcgctgttg ctggtatcgt aggtactctt cctgctgaag
    23281 ttgctgaaaa aattggtttc gtgaacaact tcaaaggttt gtctatgatt ggtatttcta
    23341 tcgtaggtat tttccttgca gtgcttcact tcaaaaatag ccaaaaagta gttgtagcag
    23401 caccttctac accatcagaa agtggggaaa tcgaagatga cgaattctaa ttacaaactt
    23461 acaaaagaag attttaatca aatcaacaaa cgtagcttgt ttactttcca attaggttgg
    23521 aactacgaac gtatgcaagc ttctggttac ctttacatga tcttgcctca gttgcgtaaa
    23581 atgtatggtg atggaactcc tgaattgaaa gaaatgatga aagttcatac tcaattcttc
    23641 aatacttcgc cattcttcca taccattatc gctggttttg accttgccat ggaagaaaaa
    23701 gatggtgtag gttcaaaaga cgccgttaac ggtatcaaga caggtttgat gggaccattc
    23761 gctcctcttg gggatacaat ctttggttca cttgtacctg ctatcatggg gtcagtcgca
    23821 gcaactatgg ctatcgctgg ccaaccttgg gggatcttcc tttggattgc agttgcagta
    23881 gcgtatgaca tcttccgttg gaaacagttg gaatttgctt acaaagaagg ggttaacctt
    23941 atcaacaaca tgcaaagtac cttgacagct ttgattgacg ctgcatctgt acttggtgtc
    24001 ttcatgatgg gtgctcttgt agcaacagtg attaactttg aaatttctta caagttgcca
    24061 atcggtgaaa agatgattga tttccaagac atcttgaacc aaatcttccc acgtttgctt
    24121 ccagcaatct ttactgcctt tatcttctgg ttgcttggta agaaaggtat gaactctact
    24181 aaagctatcg gtattattat cgtacttgct ttggctcttt ctgcccttgg tcactttgca
    24241 cttggaatgt aattccttat gactaaatca ttaattttgg tgagccatgg tcgcttctgt
    24301 gaggagctta gaggtagcac agaaatgatt atgggcccac aagacaacat ttacacagta
    24361 gctcttcttc cagaagatgg cccagaagaa tttactgcta aatttgaagc tgttattgaa
    24421 ggattggatg atttcctagt ttttgcggat cttctcggtg ggacaccttg taatgtggtg
    24481 agtcgcttga tcatggaagg tcgtgatatt gacctttacg cagggatgaa tcttccaatg
    24541 gtgattgaat ttatcaatgc gagccttaca ggcgcagatg cggactacaa gagccgtgct
    24601 gcagaaagca ttgtgaaagt taatgacctg ttagcgggct tcgatgatga cgaagatgaa
    24661 taatactctt cgaaaatctc ttcaaactac gtcaacgtcg ccttgccgta ggtatatgtt
    24721 actgacttcg tcagtcttat ccggcaacct caaaacggtg ttttgagctg acttcgtcag
    24781 tcttatccgg caacctcaaa gcagtgcttt gagcagcctg cggctagttt cctattttag
    24841 ttggaactcg attcaattca tgtgacaacg tgaaaatcgt tagagcattt tatatagaat
    24901 atacatggga atggagctta ctcccattcc catatttaat agaaaaagag gaactcaatg
    24961 ctacattata caaaagaaga cttgctcgaa ttgggtgcag aaatcactac gcgtgaaatc
    25021 taccaacagc ctgatgtatg gagagaagct tttgaatttt atcaagcaaa acgtgaagaa
    25081 attgcagcct tcctacaaga aatcgctgat aaacatgact atattaaggt tatcttgaca
    25141 ggtgctggga cttctgctta tgtgggagat accttgctac cttattttaa ggaagtctat
    25201 gacgaacgca aatggaattt caatgctatt gcgacaacag atatcgttgc caatccagca
    25261 acctatttga aaaaagatgt ggcaactgtc cttgtgtctt ttgctcgtag tgggaactcg
    25321 cctgaaagtg tggcgactgt tgatttggcc aaatccttgg tggatgagct ttatcaagtg
    25381 acgattactt gtgcagcaga tggtaaattg gctcttcaag ctcacggtga tgaccgtaat
    25441 ctcttgctct tgcaaccagc tgtctctaat gatgctggat ttgccatgac ttctagcttt
    25501 acgtctatga tgttgacaac tctcttggtc tttgatccta cagaatttgc tgttaagtct
    25561 gaacgttttg aagttgtatc tagtcttgcc cgtaaagttt tagacaaggc agaagatgtc
    25621 aaagagctcg ttgatttaga ctttaaccgt gtcatctatc taggcgctgg tcctttcttt
    25681 ggacttgctc atgaagctca gctcaagatt ttggaattaa ctgctggtca agttgcgacc
    25741 atgtatgaaa gcccagttgg cttccgtcac ggtccaaaat ctcttatcaa cgacaataca
    25801 gttgttttgg tctttggtac aacgacagac tatactcgta agtacgactt ggacttggtt
    25861 cgtgaagttg ctggtgacca gattgctcgt cgtgttgtgc ttttgagtga tcaagctttt
    25921 ggtcttgaaa atgtcaaaga agtgtccctt ggttgtggcg gtgtcttgaa tgatatttac
    25981 cgtgtcttcc cttacatcgt ttatgcccaa ctctttgccc tattgacttc actcaaggta
    26041 gaaaataaac cagatacacc gtctcctaca ggtacagtaa accgtgtagt acaaggtgtc
    26101 ataattcacg aatatcaaaa gtaagacagt gtttatgaat tcttgacaag aggatttgta
    26161 aattatcaga taaaccatag attgtcagta cgctttctat ggtttgtttg cttgagagaa
    26221 atagtaaaag gagaacagaa tgaaagcata cacagagcgt gtatttggaa atgttgaggg
    26281 cgaggatgtc ttggcctatc gatttgagac agacggtggc taccaacttg aggttatgac
    26341 ttatggcgcg accatcttgc gctatgtcgc acctgacaag gctggaaatt ttgccaatgt
    26401 tatcttggga tttgatgact ttgatagtta tgtaggcaat agtcccaagc atggagcaag
    26461 tgtaggtcct gtagcgggtc gtattgcagg tgcgaccttt gagctcaatg gtaagaccta
    26521 tgaccttgag gttaataatg ctagcaactg taatcacagt ggttcaactg gttgggattc
    26581 cagcttgttt gaagttgaag aagtaagcga tcatggcttg actctctaca cagaacgtac
    26641 agatgggaca ggagggttcc ctggaaatct caagatttgg atcagttatc acttggaaga
    26701 aactggtgcc tatgaaatta gctacaaggt aacgaccgat caggatacgc tggtcaatcc
    26761 aaccaaccac agctatttca acttgtctgg tgatttcacg cagacgattg accgtcatgt
    26821 cttccaacta aacacagagg gcatttactc aatcactcct gacggtgttc ctgccaaaac
    26881 tccagaagcc aaccgtgatg tggtcaaaca catctacaat ggtaccttgt tgaaggatat
    26941 ctttgcagaa gaagatgagc aaatccagct ggcatcaggt ttggatcacc catttgccct
    27001 tcctgtaggc catgacaatg ctggattcct ttatgaccaa aattcaggtc gcttcctgct
    27061 tttcaagaca gaagctcctt gctttgtggt ctacacagca aactttgtgg atgaaagtgt
    27121 catcatagga ggtcagccaa tgctacagca caatgggatt gctcttgaag cgcaagcttt
    27181 accagatgcc attcacagtg accttaaagg ccaagtcatt cttaaagctg gtcaaacctt
    27241 caccagtaag acacgttatg aacttgttgt gaaataaaaa agctggtcaa aaagtcttta
    27301 aaattaaaat aacgcatatt gtcaggtgat gaaaagtttg atactatgcg ttttattatg
    27361 aaatgattta ctttatctta tcctgaaatg gtgttatttt tgagttatct ggcttgactt
    27421 tcttgatgga aattatataa tagttgtaat aacaataatt acaacgagaa aagaggacca
    27481 tttatgacct atgaatacaa gagtcacatt tatttggcag agacagtttt aaatgtaaag
    27541 gatttggcca gtcaaacagc cttttatcag caagttattg gtttagaaat cttatctcaa
    27601 actgagacag agtccattct aggccttggt ggaaaagtct tggtacagct gattcaagca
    27661 caagagagcg gagaagtgag ggaacattat ggtctttacc atttggccat tctcttgccc
    27721 acacgcaagg ctttggctga tgtcttgaaa cacctgacag atttacagat tcctcttgtc
    27781 ggcggtgcag accatggtta cagtgaagct atttacttgg aagatttgga gggaaatggc
    27841 attgaactct atcgagataa gccagtttcc acatgggata ttcgagaaga tggacgcatt
    27901 atcggagtga cggaggcttt tgcggcgcag gacatttatg agttggggga aagagtagag
    27961 ccctttatcc tggcagaagg tacgagaatg gggcatattc atctttccgt caaggatagt
    28021 cgaaagtcca gccagtttta tcaaaaggtg ttagggctag aggataaatt cagtgtgcct
    28081 agcgctagtt ggattgcggc tggagattac catcatcatt tagcagttaa cgaatgggga
    28141 ggaaaaggtc tggcttcgcg taagcaaggc ttaccaggtt tagcctacta tgtcatcgaa
    28201 gtcgcacata aagaagaact gttaacgatt gtccaacgag cacaagaagt tgacgcacca
    28261 atcaaatgga tgacatcgag ccaattggaa atcacagact cagatggcat cgtgacccgt
    28321 attcgtttag caaggtaaaa ttaggaattt ctaataagtt ataagtattg ctagtttgct
    28381 ttttgaacgg tctttggtaa cagaactgcg tgagctggat gggtgagaat tttgacaaag
    28441 aagctgatta gagatataat gaagaaaaat cgagcaagga aaaagaaatg acaaattcaa
    28501 agtatattac ttgtttgaaa cgttcagagg gccagttgtg tgggattcaa aagatgattg
    28561 aaggagatcg tgactgtgct gatattgtga cgcaactgac agcagtgaga tctagtgtag
    28621 agcgcgtgat tgagatgata attaccgaaa atcttactga atgtatcaat cagccactag
    28681 atgattctga agctcaaaag gaacgcctag aaaaggctat ccgatacttg attaaacgga
    28741 aataaatgaa tgttttgaga cgatatgtgc aaaggtctat taactattag aatagtttaa
    28801 tgtgagtcaa aagaagttgt aaaaaatctt taaaattaaa aaaacgcata gtatcaggtg
    28861 ttttattatg tagagactta tactcttcga aaatctcttc aaaccacatc agcttcacct
    28921 tgccgtagat atggttactg acttcgtcag ttctatccac aacctcaaaa cagtgttttg
    28981 agctgacttc gtcagttcta tccacaacct caaaacagtg ttttgagctg acttcgtcag
    29041 ttccatccac aaccttaaaa cagtgttttg agcagcctgc ggctaacttc ctagtttgca
    29101 ctttaatttt cattgagtat tacttcatct tctcatgaaa ttgagttttt gcccagctcc
    29161 tcttgattat tctacttgac cgggccaagt attcatacca ccttctacgt tggtaacggt
    29221 gaggccttgg gagctgagaa attggcaggt agatgcagag cggactcctc cttgacaaat
    29281 aacatagtat tcatggtcag gtttgagttc tttgtagcct tgctctaagg tacttaatgg
    29341 aagatttttg gcacctggtg catgtcctgc ttggaattca tgtgcttcac ggacatcgat
    29401 aagttctaga ttttcatttt agtattttcc ataaaagtca gccatgctga tactagtttc
    29461 catattctac tccttctggg ttagccattt tgtatagtga ataagcgccg tcaaggtttt
    29521 ggacggtaaa tcctgcttgc ttgaggatag gctctgcgat atagctgcgc aaaccactgt
    29581 ggcagctgac gatgtaggct tgttttttgt ccagttcatc agcttcctcc ttgacacttt
    29641 gtcagttttt gatacaatag tacaaaatta gaggaggtgg gctatgattc agaaacatgc
    29701 gattcccatt ttagagtttg atgataatcc tcaggcggtt atcatgccca atcacgaggg
    29761 gttggatttg cagttgccaa agaagtgtgt ctatgctttt ttaggtgagg agattgaccg
    29821 ctatgcgagg gaagtagggg cgaactgtgt tggcgaattc gtttctgcta ccaagaccta
    29881 tccagtctat gtcatcaact acaagggtga ggaggtctgt ctggctcagg ctcctgttgg
    29941 ctccgctcca gcagcccagt ttatggattg gttgattggc tatggtgtgg agcagattat
    30001 ctctactggg acctgtggtg tcctagctga tatagaggaa aatgcctttc tagtccctgt
    30061 tcgcgctttg cgagatgagg gagccagtta ccactatgtg gcaccttgtc gttatatgga
    30121 aatgcagcca gaggctattg ctgctattga ggaagttttg gaagacagag ggattcctta
    30181 tgaagaagtc atgacctgga cgacagacgg tttttaccga gaaacggctg aaaaggtggc
    30241 ttatcgtaag gaagaaggct gtgctgttgt ggagatggag tgttctgctc ttgcggcagt
    30301 agctcaattg cgtggggttc tctggggtga attgttgttc acagcagatt ctctagcgga
    30361 cttggaccag tacgacagtc gtgactgggg ctcggaagct tttaataagg cgctagaact
    30421 gagtttagca agtgttcacc acctttagtt gtacaggcaa aggatttgtt ttatcataaa
    30481 atgtctagct catacttttc aaaaatatgt ttaaacgagg tcaccttcct cttgtcctag
    30541 gcatgttgag gttgggaaaa atctttaaaa tcagaaaaac gtatcatatc aggtgatgaa
    30601 aattttgata ctatgcgttt tatgttggta agatttagag tgagatgaaa tgatactctt
    30661 cgaaaatctc ttcaaaccag gtcagcttca ccttgccgta tagatgttac tgacttcgtc
    30721 agttctatct gcaacctcaa aacagtgttt tgagctgact tcgtcagttc tatccacaac
    30781 ctcaaaacag tgttttgagc aacctgtgac tagctttcta agcgatgcct tggttctcat
    30841 tgcctataat caaaaagaga aattttctcc tgaaaagcat atagagtagc tggcgttaaa
    30901 agctcctgtc ttgctttttt gacctatagt cacatctatc aagtattgtt cttgcctaag
    30961 ctatcaataa aaaggtggca ttttttaggc ttggtgttag tgaattttgc cttatcctat
    31021 ctaagtcatt tcgagctttt tatggtacaa tggaaacatg ttattcaaat tatctaagga
    31081 aaaaatagag ctaggcttat ctcgtttatc gccagcccgt cgtatttttt tgagttttgc
    31141 cttggtcatt ttactaggct ctcttctttt gagcttgccc tttgtccaag ttgaaagctc
    31201 acgagcgact tattttgatc atcttttcac tgctgtctct gcagtctgtg tgacaggtct
    31261 ctcaaccctt ccagtagctc acacctataa tatctggggc caaataatct gtttgctctt
    31321 gattcagatc ggtggtctag ggctcatgac ttttattggg gttttctata tccagagcaa
    31381 gcaaaagctt agtcttcgta gccgtgcaac tattcaggat agttttagtt atggagaaac
    31441 tcgatctttg agaaagtttg tctattctat ttttctcacg acctttttgg ttgagagctt
    31501 gggagctatt ttgcttagtt ttcgccttat tcctcaactt ggctggggac gtggtctttt
    31561 tagttccatt tttctagcga tctcagcctt ctgtaatgcc ggttttgata atttagggag
    31621 caccagttta tttgcttttc agaccgattt actggtcaat ctggtgattg caggcttgat
    31681 tattacaggc ggccttggtt ttatggtctg gtttgatttg gctggtcatg taggaagaaa
    31741 gaaaaaagga cgtctgcact ttcatacgaa gcttgtacta ttattgacta taggtttgtt
    31801 gttatttgga acagcaacta ctctctttct tgagtggaac aatgctggaa cgattggcaa
    31861 tctccctgtt gccgataagg ttttagttag cttttttcaa acagtgacga tgcgaacagc
    31921 tggcttttct acgatagatt atactcaggc tcatcctgtg actcttttga tttatatctt
    31981 acagatgttt ctaggtgggg cacctggagg aacagctggg ggactcaaga ttacgacatt
    32041 ttttgtcctc ttggtctttg cacgaagtga gcttctaggc ttgcctcatg ccaatgttgc
    32101 gagacgaacg atcgcgccgc gaacggttca aaaatccttt agtgtcttta ttatcttttt
    32161 gatgagcttc ttgataggat tgattctgct agggataaca gccaaaggca atcctccctt
    32221 tatccacctc gtatttgaaa ccatttcagc tcttagtaca gttggtgtaa cggcaaatct
    32281 gactcctgac cttgggaaat tggctctcag tgttatcatg ccacttatgt ttatgggacg
    32341 aattggtccc ttgaccttgt ttgttagctt ggcagattac catccagaaa agaaagatat
    32401 gattcactat atgaaagcag atattagtat tggttaagaa aggaaagagc atgtcagatc
    32461 gtacgattgg aattttgggc ttgggaattt ttgggagcag tgtcctagct gccctagcca
    32521 agcaggatat gaatattatc gctattgatg accacgcaga gcgcatcaat cagtttgagc
    32581 cagttttggc gcgtggagtg attggtgaca tcacagatga agaattattg agatcagcag
    32641 ggattgatac ctgcgatacc gttgtagtcg cgacaggtga aaatctggag tcgagtgtgc
    32701 ttgcggttat gcactgtaag agtttggggg taccgactgt tattgctaag gtcaaaagtc
    32761 agaccgctaa gaaagtgcta gaaaagattg gagctgactc ggttatctcg ccagagtatg
    32821 aaatggggca gtctctagca cagaccattc ttttccataa tagtgttgat gtctttcagt
    32881 tggataaaaa tgtgtctatc gtggagatga aaattcctca gtcttgggca ggtcaaagtc
    32941 tgagtaaatt agacctccgt ggcaaataca atctgaatat tttgggtttc cgagagcagg
    33001 aaaattcccc attggatgtt gaatttggac cagatgacct cttgaaagca gatacctata
    33061 ttttggcagt catcaacaac cagtatttgg ataccctagt agcattgaat tcgtaaagag
    33121 ggatgacccc tcttttttga tgcctaagat ggcaaataga gacagaagcc ccttgtcttc
    33181 tagtaaaagt tcttcaaagg ctggacttta tggtaaaata gaaagaagtg acaagagaga
    33241 gtaatactca atgaaaatca aagagcaaac taggaagtta gccgcaggtt gctcaaaaca
    33301 ctgttttgag gttgtggata gaactgacga agtcagatca aaacac
//
LOCUS       DAVEHY010000023        32463 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVEHY010000023 DAVEHY010000000
VERSION     DAVEHY010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32463
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.023"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(418..1107)
                     /gene="rplA"
                     /locus_tag="VUZ44_001333"
     CDS             complement(418..1107)
                     /gene="rplA"
                     /locus_tag="VUZ44_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU0320245.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1315..1740)
                     /gene="rplK"
                     /locus_tag="VUZ44_001334"
     CDS             complement(1315..1740)
                     /gene="rplK"
                     /locus_tag="VUZ44_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU0320246.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1863..2579)
                     /locus_tag="VUZ44_001335"
     CDS             complement(1863..2579)
                     /locus_tag="VUZ44_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU0320247.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2597..3058)
                     /locus_tag="VUZ44_001336"
     CDS             complement(2597..3058)
                     /locus_tag="VUZ44_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU0320248.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3060..4097)
                     /locus_tag="VUZ44_001337"
     CDS             complement(3060..4097)
                     /locus_tag="VUZ44_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU0320249.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4195..5520)
                     /gene="brnQ"
                     /locus_tag="VUZ44_001338"
     CDS             complement(4195..5520)
                     /gene="brnQ"
                     /locus_tag="VUZ44_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU0320250.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5691..5783)
                     /locus_tag="VUZ44_001339"
     CDS             complement(5691..5783)
                     /locus_tag="VUZ44_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU0320251.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5826..5978)
                     /locus_tag="VUZ44_001340"
     CDS             complement(5826..5978)
                     /locus_tag="VUZ44_001340"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU0320252.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6138..6716)
                     /locus_tag="VUZ44_001341"
     CDS             complement(6138..6716)
                     /locus_tag="VUZ44_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU0320253.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6770..8170)
                     /gene="pepV"
                     /locus_tag="VUZ44_001342"
     CDS             complement(6770..8170)
                     /gene="pepV"
                     /locus_tag="VUZ44_001342"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU0320254.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8183..8788)
                     /locus_tag="VUZ44_001343"
     CDS             complement(8183..8788)
                     /locus_tag="VUZ44_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU0320255.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            8959..9759
                     /locus_tag="VUZ44_001344"
     CDS             8959..9759
                     /locus_tag="VUZ44_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0320256.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9943..10776)
                     /locus_tag="VUZ44_001345"
                     /pseudo
     CDS             complement(9943..10776)
                     /locus_tag="VUZ44_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10766..12613)
                     /gene="uvrC"
                     /locus_tag="VUZ44_001346"
     CDS             complement(10766..12613)
                     /gene="uvrC"
                     /locus_tag="VUZ44_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU0320257.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEIYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12653..13354)
                     /locus_tag="VUZ44_001347"
     CDS             complement(12653..13354)
                     /locus_tag="VUZ44_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU0320258.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13433..14665)
                     /gene="murN"
                     /locus_tag="VUZ44_001348"
     CDS             complement(13433..14665)
                     /gene="murN"
                     /locus_tag="VUZ44_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU0320259.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14670..15890)
                     /gene="murM"
                     /locus_tag="VUZ44_001349"
     CDS             complement(14670..15890)
                     /gene="murM"
                     /locus_tag="VUZ44_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU0320260.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16002..16781)
                     /locus_tag="VUZ44_001350"
     CDS             complement(16002..16781)
                     /locus_tag="VUZ44_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU0320261.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16850..18511)
                     /locus_tag="VUZ44_001351"
     CDS             complement(16850..18511)
                     /locus_tag="VUZ44_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU0320262.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18686..20908)
                     /gene="recJ"
                     /locus_tag="VUZ44_001352"
     CDS             complement(18686..20908)
                     /gene="recJ"
                     /locus_tag="VUZ44_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU0320263.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21185..21738
                     /locus_tag="VUZ44_001353"
                     /pseudo
     CDS             21185..21738
                     /locus_tag="VUZ44_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21749..22543
                     /locus_tag="VUZ44_001354"
     CDS             21749..22543
                     /locus_tag="VUZ44_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU0320264.1"
                     /translation="MKKKFFLSALLISLFSLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22556..23233
                     /locus_tag="VUZ44_001355"
     CDS             22556..23233
                     /locus_tag="VUZ44_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU0320265.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFCIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23243..23902
                     /locus_tag="VUZ44_001356"
     CDS             23243..23902
                     /locus_tag="VUZ44_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU0320266.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVPVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24198..25388
                     /locus_tag="VUZ44_001357"
     CDS             24198..25388
                     /locus_tag="VUZ44_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU0320267.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCSPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25709..26590)
                     /locus_tag="VUZ44_001358"
     CDS             complement(25709..26590)
                     /locus_tag="VUZ44_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU0320268.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26731..28059)
                     /gene="vncS"
                     /locus_tag="VUZ44_001359"
     CDS             complement(26731..28059)
                     /gene="vncS"
                     /locus_tag="VUZ44_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU0320269.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28056..28712)
                     /gene="vncR"
                     /locus_tag="VUZ44_001360"
     CDS             complement(28056..28712)
                     /gene="vncR"
                     /locus_tag="VUZ44_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU0320270.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28761..28844)
                     /gene="pep27"
                     /locus_tag="VUZ44_001361"
     CDS             complement(28761..28844)
                     /gene="pep27"
                     /locus_tag="VUZ44_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU0320271.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(29024..30403)
                     /gene="vex3"
                     /locus_tag="VUZ44_001362"
     CDS             complement(29024..30403)
                     /gene="vex3"
                     /locus_tag="VUZ44_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU0320272.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30455..31102)
                     /gene="vex2"
                     /locus_tag="VUZ44_001363"
     CDS             complement(30455..31102)
                     /gene="vex2"
                     /locus_tag="VUZ44_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU0320273.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31115..32392)
                     /locus_tag="VUZ44_001364"
     CDS             complement(31115..32392)
                     /locus_tag="VUZ44_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320274.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9177 a         7438 c         6034 g         9814 t
ORIGIN      
        1 caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact atagtagatt
       61 gaaactagaa tagtacacct ctacttctaa aacattgtta gaaatcgatt tgactgtcct
      121 gaacgattcg tcctattctt atttcatttt attataattg atagtggtcg ccccagccag
      181 ataccttatc cgctatatag gccttattat cacgttcctg ttcgtagagc cacgatttcg
      241 ctatcccttc ctctgacgat tcttatttcc agcgtcagac ttgggaatcg ctattgggtt
      301 caccggtagt aggtgcccac cgaggactta cacctcagat atacgacatg cccgtcgtac
      361 atcaaaaaaa gttgagacat agtgtcttca acttttttac attactttaa ctactgatta
      421 aagtgagttt acgtcaactt tgataccaac accttgagta gttgtgatag tcaagtttgt
      481 tacgtaagtt cctttagctg tagctggttt tactttttgg attgtttcgt tgaaagcttt
      541 aaagttttca accaattttt cagcttcaaa tgatacttta ccgatgattg cttgaacgtt
      601 acctgcacgg tcagcacggt aagtgatttt accaccttta gactcttcaa ctgctttagc
      661 aacatccatt gttacagtac cagttttagg gtttggcatc aagttacgtg gtccaaggac
      721 acgtccaaga cgtccaacaa gagccatcat atcaggtgta gcgataacta cgtcgaagtc
      781 caaccaaccg tcgttgattt tagcaacaag gtcatcttca ccaacaaagt ctgcaccagc
      841 agcttttgct tcttcagctt ttgcaccacg tgcgaaaaca agaacacgtg aagttttacc
      901 agtaccgttt ggcaatacca ttgctccacg gatttgttgg tcagcttttt taacgtcgat
      961 gttcaagttg taagcaactt ctacagttgc atcaaatttt gcaaagttag tttcttttgc
     1021 aagtgctaca gcttcttcta cactgtatgc ttttgtgctg tcgattttct caagagcagc
     1081 acgaagttgt ttgctttttt tagccatttt ctattctcct tgtaagtggt tcaatcgatt
     1141 ttcatctccc acgtcacttc tcgaaatgat gaagtcttgc gggttttcag tctactattt
     1201 ttctcttcct acggccttaa gctcccttgc tgtatccaag tacaagcctc agtcacttgc
     1261 ctagtatgaa aagcaactaa tagactgctg tgagattttc tactgtgtta ttgattagtc
     1321 aacaacagtg aatcccatag aacgagcagt accttcgatc atacgcattg cagactctac
     1381 gtttgctgcg ttcaaatctg gcatcttagt ttctgcaatt tcttgtactt gtgcacgagt
     1441 aactgtagca actttagttt tattaggtgt acctgatcct ttttcaacac ctgcagcttt
     1501 tttcaaaaga acagcagctg gtggtgtttt cgtaacgaaa gtaaatgatt tatcttcgta
     1561 aactgagata acaactggaa tgatcatacc agcttggtca gctgtacgag cgttgaactc
     1621 ttttgtgaat cccatgatgt tgataccagc ttgaccaaga gcaggtccaa ccggtggagc
     1681 tggtgtagct ttaccagcag ggatttgcaa ttttacaagt ttttcgactt ttttagccat
     1741 ttttaaatcc tcctttgtgg ttttggcggt aattagagat ttttacctcc cacaagtatg
     1801 ctttacacat acctttccat tatacactat ttatctaaaa atgcaagaga aaactttcat
     1861 ttttaatcga cataatcgcc gccttcaaag ccatagtact cttccaaact gagaccactt
     1921 gcagcaattt ctttggcttc ttttccaacg tagcggagat gccattcttc tgccatgtag
     1981 ccagtctcct tttccttgcc tttaagatag cgaacaacaa agccatagtc agccgcatgg
     2041 tccaagagcc actgggctgc cttttcttca gtaactaaat ccccatctgt cccaatcaaa
     2101 tcaaaagcaa gacccgtctg gtgttcactg taacctgggc gtgctgagta gcgatctgct
     2161 gcttccttac catcttgatt gacatagtct tggtagagct tagcctgagt ttcataactc
     2221 ctaaacccac tgtattggtc actgattgga tagccctcag cctgcatagc tgcgattagt
     2281 ttgagcaact ctgccttggc tgttggattt tctcctggat tgtaatcttt tgacaaagga
     2341 taacgtttat tagctaggat aatctcatcg tatttccctt ggatactata atagctccct
     2401 ttattgctaa cttctgcctt tttctgacta gaagcttgag atttgctacc tacagttcct
     2461 tccggttgac tgctttgctc cgttttttga gtgttttctt caactttggt tttttcttgc
     2521 gaacaagctg caagggtcaa tgctagtaaa ccagataaaa tgacatatct ttttttcatt
     2581 tctttcttcc tctctcttag gccaaatact tctccaattc atgagataag attttaatca
     2641 tctcttccag ctctggcgat tgtacttggc aatcttctgc cgccatttct tcccagggca
     2701 cccaccagac tgggccacgg ccattcaaac cgtgactctt catatcacct gctcttcggg
     2761 gaaaaagatg ccaatgagcg tgggcatcgc catttcctag gagttcaata ttcatctttt
     2821 cagcctcaaa tgctttggcg actgcttctt ggactaaact catttcctct aaaaagcgaa
     2881 gttttacaga agtttccata tgatggagtt ctgtgacatg atcttttgct aaaaataagg
     2941 tatagccctt aaagtattgg tagtcaccaa taacaacata gcctgtttct agttctttta
     3001 caaagtaggg attttgccca gctttaatga gttcgattct ctgacagatt aagcacattc
     3061 tatgataccg cctcgctctt aagataagca tcaaccatac gctcagtcgc tattactgaa
     3121 tcgatgtggg tgcgctcata agagtgactg gactcaatac cagctccaag aagtgcatgc
     3181 ttgacctctg cacctgctga catcgctgct gaagcgtccg atccgtaaaa tggatagatg
     3241 tcgagcttaa atggaatatc ttgctcttta gccaaggcaa ccaagtgttg acggaagtca
     3301 tagtgataag gacctgaagc atccttgaca cagatagata ctgtgtactc atctgtctgc
     3361 tggtcatctc ccatagctcc catatccaca gccagatatt ctactacctg agcaggaatg
     3421 ttagaattag caccatgtcc tacttcttca aaaactgaaa aagcaaaatg agttgttact
     3481 ggcaattcaa tcttctcttt cttataaata cgaagcaggt tgagcaaaat cgctgcgctg
     3541 accttatcat ccaaatgacg agacttgata aaacctgtat cagtcacaac agttcgtgta
     3601 tcgaagctga taaaatcacc gacctcaatc ccaagagcac gagtttcttt ttcattgctt
     3661 acttttacat ccaaacgcac ttccatattg tcctgcgtgc gttctgcagt tcctgcatcc
     3721 ttgtagacat ggcaagaagt ttggtggatg aggatggttc ctgatacctt ttgacctgtg
     3781 ctagccacat gaacggtaca gttttcacct tcaatcatgt tccaaggaaa accaccgata
     3841 cggtccaatt taagacgacc atctggtttg acagcacgaa caatagcacc cagcgtatcc
     3901 acatgggcag tcacatagcg atgttgctca tcattttgac ctttgatggt cacattgaca
     3961 ccacccttag ctgtgcgaac tggctggtaa ccaaaacctt ctagagtctt gactaaataa
     4021 ttcgaaattt cacgagtgaa gcccgttggc gatgcgatgg ctgtcagttc tttgatatat
     4081 tctactgttt gattcatttc ttcacctctt tcgctaccta ttataacaca tttatcatcg
     4141 gataaaaaaa gaaaatcact cctgtagact tggctacaaa agtgatttaa gtgattattc
     4201 catttcaaaa acatcgcttt cttgcttgtt tggtagaacc aatgagagca agattccaac
     4261 aatggctggc accaaccatg ggagagatgc cttggcaaaa ggaagaacgc taacaagatt
     4321 tgcaagaaac tcaaccttaa acgagcttcc tagtacgctt gcaatggcaa taactgtaac
     4381 cacagcaatt gtcaactgca tacctggttt tgaaagggca acaaatttgt tgacaatgac
     4441 aatcataacg atagcaatcg tgattgggta caagataacc agtactggaa ttgagtactt
     4501 gataatcgca tcaagaccca aattggcaat agcaaatcca atcaaggtaa aggctgtcgc
     4561 ataaaccttg tagctgattt gtgggaagcg ctcattaaag aactcagctg ttgacacaat
     4621 caaaccaaca gtcgttgtga agcaggttac ggtaaccata gctgcaagga agagttgagc
     4681 tgttgagcca aagatttctt gagtggcttg tgacaagatg taaacacctg gtgttccacc
     4741 cttcatcgct tcagctggta ctgggaaatg atttccaaga aaacctaaac cgatgtaaag
     4801 agcgctgaag gcaagggcaa caacgatacc aacaacccaa atagttgaaa tgtattcttt
     4861 cttacttgaa aatccaagtt gtttcaaggt ttgaactgcg attacgctaa aggccactga
     4921 agcaagggcg tccaaggtat tgtaaccttc taggaaacct gtaccaaagg cagaagcttg
     4981 ataagcagct gaagcagctt gaggacttgt tccaccatat ttgatagctc ccagaacgac
     5041 caagataaca atcaaaattg caaagactgg cgttaaaaca cgtccaatgc ggtctaagat
     5101 ttttgatgga ttaagcgaaa tcaaataggc tgccgcaaaa tacagaaccg taaatacaat
     5161 caagccaagt cctttatttg catccgacaa aagggggcta atccctactt cgtaagctgt
     5221 tgtagcagta cgtggggtag caaagaatgg accgattgac aagtaaagaa ctgagaggta
     5281 aagagtcgca aaccaaggcg ctatcttcgt tgaaatctcg tagatatatc ctttaggatt
     5341 tagcgttcca ataataaggg tcaagacggc gataccaacg cctgaaaaga caaaacctgc
     5401 gatggcagga agaaaatgtt ctccagatag agcacctaga gaaggcggaa aaatcaagtt
     5461 ccccgcacca aaaaatattc caaacaggag caaacctgtt agggtacctt ttttagccat
     5521 aaaaatctcc ttcatattta taaaatactg acctagtata ccacgattag gagtctgaaa
     5581 aaagcatcac gaggcaaata ttaaatgttt tcaattttct taaaaataag aattatctaa
     5641 aaataaaact ctcctaccca gtccacacca agtaggagaa atgcaaaatt ttaaagttct
     5701 tcaaaggcta acatgccacc ctggacattg ataacattat aaccttgttc taacaggaat
     5761 tggcaagcac gcgccgatct cattccagat ttgcaaataa tataatgcaa gcgatctttg
     5821 tccaattaat cataactatc agccaattga ctaagcggta ggttgtgggc accttctaaa
     5881 tgaagagctg caaactcatc cacttctctc acatccacta gagaaagctg gtcgttttgg
     5941 taaagctggt aaaatgcgtc aaaggctatt tctttcattc tttttcttct aatactcttc
     6001 gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtgc gtatgttacc gacttcgtca
     6061 gttttatctg caacctcaaa gctgtacttt gagcagccta cgactagctt cctagtttgc
     6121 tctttgattt tcattgacta taaaatggtt ttaattcttt ttttcaaatc tggcactact
     6181 tctgcctcaa accaaggatt tttggccatc cagatttgat ttcgtggtga tgggtgaact
     6241 agcggaaaat aggctggcag atagtcttta tagtgtttca ccctctccgt taccttccca
     6301 ctgattttct cctgtaaata gtaggcttgg gcatattgcc caatcaagag ggttaactga
     6361 atatcaggca attcctgtaa gagctgcgga tgccattttt ctgcaaaacc tgtacgaggc
     6421 ggaagatcac ccgacttgcc atgtcctgga aagtagaaat ccataggcaa aacagcaaaa
     6481 taacctgaat tgtaaaaggt atcttcatcc acacctagcc agtcccgcaa gcggtcacca
     6541 cttttatctt tccagtaaag gcctgcttct tgagttttaa gtcccggagc ctgaccgatg
     6601 atattgatgc gagcagtttt tggcgctgca aagagaggct caatgccacg ctctgtatag
     6661 ctggcattct gtgaatccgc catgatagcc tgtttgattc tttcgatttg agacatctac
     6721 tttccctcca aaaagaagtc caagcataag atctcagact tctatcgttt tatttgatca
     6781 attcgtaaat agcttcggca tagattgctg ctgctcggaa gagatcgtcc aaggcgataa
     6841 attcattggc ttggtgcatg gtatcaattg agtctgggaa catagcacca taggcaactc
     6901 cgcgctctaa caagcgacca aaggttccac caccgatgac ttgttcatga cctttaaagc
     6961 cagtttgttt ttcatagata ttcaacaagg tttgcacaag tggatcttcc attggcacat
     7021 agtgaggcgt gtgaccgtgt tcagacaggc taacagaaac aactggcaag ttttcaagga
     7081 ttgacttgat ttgttctgga cttgttcctt ttggatagcg gatgttgagg gcaatggtat
     7141 tatcagcact tgtttcatcg aagcggaaga cgccggcatt catagaaaga gcacccatct
     7201 tttcatccac atgagcaatc ttaagatttt caccctcatg atcgttcaag agaattttac
     7261 ctgcgatgtc aaggtagtct ttggctggac cagcaaagcc aaactgactg aggaagaggg
     7321 caaggtaagt tgcgccattg acacctgaag caggcatagc accgtgggct gatttaccaa
     7381 tgatcgtcac cttgtatttg ccagcttctt cttggagttc tcctctaagt ttgtgttctg
     7441 caacaaaggc atctagttta gcttgcaagt cagccaagtc acctgaaacg actgctgttg
     7501 ctgattctgg taccatattt tcacgtaaac cacctgtaaa gctgtgaaga cgggcaacac
     7561 ctgtattttc tcctgcaaag tggaggtatt ccgtgatatt tcctttttca ccattgatga
     7621 ttggaaattc agcatctggt gagaaaccga aatctggttt ggcaagtcct acgtgctcaa
     7681 agtagtagtc catgtctgcc cagcctgatt cttcgtctgt tccaacgatg aagcgaactt
     7741 tcttagaagt tggaagaccc aattctttga tgattttcaa accatagtaa caagctgttg
     7801 taggaccctt atcgtccgaa gccccgcgcg cataaaggcg accatctttg atagttggtg
     7861 tgtaagggtc tgtgtcccaa ccgctaccag caggcaccac atccatatgg gcaaagattc
     7921 cgagaacttc ttctccatca ccaaactcaa aatgtcctgc atagttatca acattcttag
     7981 ttgggtagcc atcgcggtct gcgatttcaa ggaatttctc caaggctttt actggaccag
     8041 gcccaaatgg atgctgggca tcagccttgc tgtcatcacg ttctgaattg atttccaaaa
     8101 ggctaaacaa gtcagccaag aggtcttctt tgcgtttttc tacttctgct gtaaaatcaa
     8161 ttgctgtcat tttttcttct ttctatcttt tctcgatgat ttcatctact ggcaagcggt
     8221 agcttggttc caatttttcg tctgtataac ccactgtgat caagagttct gggcggaaac
     8281 ggtcttcgat ttccaaaact tcattaactt ttgatttgtc aaaaccaaga ataatgttag
     8341 aaccaattcc ttggtctgtc aatgcaagaa ccaagttcat ggcaaccaaa cctgcattga
     8401 gagctaggta gtcgctgact tgttgttcat tgtagcgtgc aaattcagct ggcaaatttt
     8461 tcatgaagta ttgaagttgt tcttctgaga aattgttagc accaccaact cgggcaatct
     8521 tacgagcgcg tttggcaagg tctgtatctg taaatagggc aatggttaca ggtgctgatg
     8581 atacctgctc aaagtttgaa ccataagcca actttgccag ttcagcattt ttctcacgaa
     8641 caactacaaa tttccaaggc tggctgttgt gggcgcttgg cgccaaggtt gcaatttcga
     8701 tagccgtacg cacatctttt ggatcaacag gcttatcagt gaaatgcttg gtcgcatgac
     8761 gttttttatt taattcaaga aatttcataa tcgatttcct tttctaattc tactgcttcc
     8821 attctaccat aatttgaaag agcttgcagg gatttttcat gattaagttt ttctatcaca
     8881 gacataaaag atatatattg gtttatcagg aaagtttctg ataaactagc aagtacttta
     8941 catttgaatg gagacagtat gaaaaaattt agcctattac tagctatcct accatttttg
     9001 gttgcctgtg ggaatcaagc tacacccaaa gagactagcg ctcaaaagac aatcgtcctt
     9061 gctacagctg gcgacgtgcc accatttgac tacgaagata aaggcaatct gacaggcttc
     9121 gatatcgaag ttctaaaggc agtagatgaa aaactcagcg actacgagat tcaatttcaa
     9181 agaaccgcct gggaaagtat cttcccagga cttgattctg gtcactatca ggctgcggcc
     9241 aataatttga gttacacaaa agagcgtgct gaaaaatacc tttactcgct tccgatttcc
     9301 aacaatcccc tcgtccttgt cagcaacaag aaaaatcctt tgacttctct tgaccagatc
     9361 gctggtaaaa caacacaaga ggataccgga acttctaacg ctcaattcat caataactgg
     9421 aatcagaaac acactgataa tcccgctaca attaattttt ctggtgagga tattggtaaa
     9481 cgaatcctag accttgctaa cggagagttt gatttcctag tttttgacaa ggtatccgtt
     9541 caaaagatta tcaaggaccg tggtttagac ctctcagtcg ttgatttacc ttctgcagat
     9601 agccccagca attatatcat tttctcaagc gaccaaaaag agtttaaaga gcaatttgat
     9661 aaagcgctca aagaactcta tcaagacgga acccttgaaa aactcagcaa tacctatcta
     9721 ggtggttctt acctcccaga tcaatctcag ttacaataac actcttcgaa aatctcttca
     9781 aaccacgtca gctttatctg caacctcaaa gctgtgcttt gagcaaccta cggctagctt
     9841 cctagtttgc tctttgattt tcatattgag tataagatat attaaaagcg atgggatcag
     9901 ccaatcgctt ttttagtttg cattggttat tttaggaaac tcttacaaaa aatcaaaaaa
     9961 attcttcaca tcctctacat acctatgctt ttctattaag cttgctaata gttccagatt
    10021 gtgcctctga tagttatctt cacgacgtag ttcttcatac atttcgataa agggaaaacc
    10081 cttggatttg gcaaattcta actcagcctc gtaatcataa gcgactttac gaaataggat
    10141 atttaccaat tccccatctt caacctctat cacggcatac tgggcacggt gattttttaa
    10201 cgcctcccaa ttaaaatagg gcatgccaat cgaccctgga ttgatgattt gttgcccttg
    10261 actaccataa cgaagcaact acttgtgaac atgaccataa actgccacgt ccgtttccgc
    10321 atctagcagt tggtcaaatt tctctgtatc attctcaact agcaagtcac caccatagtt
    10381 tttgtcaggt aaattatgag agatagaaaa gcgcaatccg tcaatttctt tcttttccag
    10441 caaaggcaag cttcgtagcc agacaatcgt tgcaggatcc attcgctcca tcaaatactg
    10501 tgtcatacgc aagagctgaa cttcctgtgg gtcttctaag ccatattgcc catctaaagc
    10561 ctcaaggaca caatcatccc aattgcctcg aacacttgcc gtgataggaa gttcctttaa
    10621 cagagcgacc aagtcatttg cacctggacc agggaggaaa atgtctccca tgagccaata
    10681 ttcactggct ccttgagttt tagcatctgc aatcactgct tctagcgccg tcgcattgcc
    10741 atgaacatct gataaaattg cgattttatg gtttattgtg gtttccttcc gtttggtaat
    10801 ctactctttc ttccgccact tgaagcaaga tttctgtttc ctgcgggttc aacttggttt
    10861 gcacagcctc tgctactgct cttggtactc caacttcgac aatctcatcc acactggctt
    10921 ccttgatttt ggtcagagac ttgaagtgcc tcatgagatt ttgcttgcgt ttaggtccca
    10981 gaccatcaat cccatccaat tgagatgaga aagaattttt ggagcgcagt tggcggtgga
    11041 aggtaatggc aaagcggtgg acctcatctt gaatgcgttg gaggaggaaa aattcctgag
    11101 aattgcgaga caagtccacc acttccagcg gatctccaaa gagcaattca tgggtttggt
    11161 gcttatcatt cttttgcaga cctgcaattg gaatatccaa gcccagttct tcttggatga
    11221 cttgcttagc aatattgact tgaccttgcc ccccatcaat cacaatcaaa tctggaggag
    11281 tcaaagcctc acgctgtact cgaccatagc gtctgcgaat gacctctcgc atactggcat
    11341 agtcgtctgg cccgactacg gtcttgattt tatacttacg gtaatccttc ttactaggct
    11401 tgccgttgac aaagaccacc atggctgaaa caggactagt tcccatgatg ttggagttat
    11461 cgaaggactc gatgcgaact ggggttggga tttgaagcaa gcgtcctaga ttttcaatag
    11521 ctccttgggt cttctcgaca gatttctcta gcaggttgaa cttctgctct aggctaacac
    11581 gggcattttt tatagctaaa ttgaccagct gctttttctc tccacgttga ggcttaagaa
    11641 tcttggaatc caccaaggcc ttgacagcct cttcgtcaat atcttgcgga atcagtacct
    11701 cattgggaac tagatgggat ttttcttgat agaattgtcc tacataggtc aaaaaatcct
    11761 catctggatc attgaagtag gggaagagat tgacatcgcg ctcgatgagc ttaccctgac
    11821 ggacaaagaa aacctgcaca cacatccagc ccttatccac atagtagcca aagacatcgc
    11881 gattttggag atccttagcc atgacccgtt gcttggttcg aagcgttcca atagcctgaa
    11941 tcaggtcacg gtattccgcc gcacgttcaa actccatagt ctgggctgcc gctgccattt
    12001 tgccctttag ctcatcaatg attttgttat cctgcccttt cagaaaatca gaaacctcct
    12061 gggccataga cttgaaataa atctcatcct tcttacagat ggtgtgggcc atgcattgac
    12121 cgatatggta ataaaaacag accttagagg gcgggttggt acacttacga aaagggaata
    12181 tccgatccag caaccgcttg atttcattgg ctgcccccac atcgggatag ggtccaaaat
    12241 aaagacctcc gtcctttttg acctgacgag tgataatcaa gcgtggatag cgctcattgg
    12301 tgattttgat gaaaggatag gacttgtcat ccttgagcat gatattgtac ttgggcttgt
    12361 tttccttgat caggttgatt tctaggagaa gtgcctcaat attagactcc gtaacaataa
    12421 attcaaaatc cacaatttca gacaccagag cctctgtctt ggtatcatga cttccacgaa
    12481 aataggaccg tactcgatta cgcagatttt tagcctttcc tacatagata atggtgccat
    12541 ttttatcctt atgaatgtag caaccagggc tggtcggcaa gagctctagt tttgatttaa
    12601 tcaagttgtt catagttcca ttatagcaaa aaaagtaggg aaagatagta ccctactcac
    12661 tagtctcata tatttttcgg aggtttgcaa catcctcttc ctggatacca taaaaggaac
    12721 ctgctggttg catgacagac ttctcatctg tatggtccaa gccaatcgca tgacctaact
    12781 catgttctgc cgtatggaca aggcgttcat aggagtagcc atagtatgga ttggacaaat
    12841 aataatgatt caaccgcacc gttacggaca agaattgccc tgttaagaga ttagtttgac
    12901 tttccgcctc tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg
    12961 ccttactaga ctcagtcacg agttcaaagt taaaagcacc agtttgattc cagttctgga
    13021 ttgcttctaa ataagcctct tgaaagcgtg aatccatctg cggatccagg taaatacgag
    13081 cagaggcctg tgcccacctt ccttcagaat gctggtgact atctgtctgg cttaacttag
    13141 gcagttgccc tgttttctcc cattggtcaa tactttgttg accaattttt actgaccgtt
    13201 ctgcttgctt tagcgctcct tgaaaatctc cgttcagata ccagagaagt ccgaaagcaa
    13261 gcacacataa gagcacaact atccaaacca gacgccaaaa caaacgccac acaaaagaaa
    13321 agaaagcccc tatcaaacga aaaagccagc gcatgtctct ccacctttct agcaaataag
    13381 aattatttta ctaaaagaag ctaaaagaaa tctaaatact gactttttca tcttaacgtc
    13441 ctactatttt tttgagtaac tggatagctt tgtattttaa aggagatgga tggtaacgga
    13501 aagtacctgc tttgcgtaca atatagccat taaaattctg tttaaaacgc aaaacaccat
    13561 cacttccatc aaaaatccct tgaatgccta ggaagttgta tttaggtatt ccacgtttta
    13621 tgctttccaa cataacatat ttttgaagca gggcaggggc atagaactta ttaaactcag
    13681 tgtaggaacc actaaagaga taagtcgttt cctgaggcat ataaacaaat aaactcccag
    13741 ctaaaacaat atcttcttct ccatattttt caatcaagtc tcgcgcttct gcttttcgaa
    13801 cttcaaacgt ttcaaattga ctagaatatt ctctcagttg attttgtttt ttctcagaat
    13861 gaggattttt actcaaatca agtcgcaact tgtccaagtt ttcttctagt ttactttgtt
    13921 caccttgcaa tttgctcata tagtccgaaa aatttaagct tgctatgaga aactccgctt
    13981 gttctccaaa agtatcataa aaatgctcat aatattctaa acttttatca ctatattctc
    14041 tacgttcaga ggtttctttt gttatattct taaaaatcga tagttcttca cgttttaact
    14101 ttttcaaccg aatgccaaag gtttcagcct ttttcaccaa gggtttaccc tttttgctaa
    14161 aacttttaag caaactcttt tcagttaatt cagttaaatc tttatagtat aaccaatctg
    14221 gttctccacc tgggtaacct gttgttaagc catcaaattg ataacctaaa tcagtcaaac
    14281 cttgaataat actttttttc tcagcatcta ttggattacc ttggctatca aaagtttgat
    14341 aagtttcata aggttttaca agcaactcta atacaccatt ttgcttggca tattctttta
    14401 actctgcata aaaaactgga agagcatctt gttgggtata aattggcccc gaattgagtt
    14461 ccatatgcag accacccagc atgggcaagc tataaaccag agctgcaact tgaatttctc
    14521 cttcttgttt caaagcaaga taaacaattc gagcccctct tttttctagc aaatccccca
    14581 tctggacaga ttgcataaag gaacgagaag aaacctgatc agaataagtc tgaaactctt
    14641 ctttcgtgag tgttgttagt gccatatact tactttctat gtttttttct taatgtttta
    14701 cggaaatcaa gagcaagtct taacagagga tagagaggat gagtgggcat tgtaaattca
    14761 cccaagtatt cttcaatcgt tggattaaat ttttccttaa aatgataaag tccaccattg
    14821 agagagtttt caacaccacc taaattttgc cagaccatac ctcgctcaaa ggcatagcga
    14881 gccgtttcat accatgttaa aattggtgca ttgtaacgtt taaaatcatc atccatacca
    14941 gcatatatat taacagaggt agtaccaaat tccaaactca aagtagccgc taaaggaact
    15001 ctcgcttgac ctacatctat atattcctgc aagaaggtca attcctctaa caaacgttct
    15061 ttttccttct tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa cgtctcttcc
    15121 aaggctctat ttttcgctaa ctgttcttct aattcttgcg aacgtttaga aacatccaag
    15181 gtggccaagg tgatataggc cttgtcctta aaattatcta acaatttttt ataataggct
    15241 tcattcctca aatgaatctc ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa
    15301 tctaatagtt ccagtccacc atattgaatc tcaagccctt tgtttcgtgc tgttcgaata
    15361 gcctgttttg ttgacttgga aagtttatct tcttcaaaat tttccttgta tattttcgcc
    15421 tgaatacgag gttgaatggt gtctcccatt tcctccgttt ttcctgacca ccttactccc
    15481 atttgttgca aactatcaat aatagccaga ttttcaggaa attctgtctt ttcctgattg
    15541 attaaacttt gagataggca aatacttggg tcaaaagtca caaaaaccgc tctcttactg
    15601 cgagcatagg acttaataga ctgaatggca aaattcaaga gttctttatc cccataatcc
    15661 aatataggtc ctcttgggat gtaaaacatt ttatagccta gcggaagagt tctaatcaaa
    15721 atactagctg tcgccagtaa tttttcttcc ctgtaaacac caaacttctc atgttgccaa
    15781 ttagacttaa cttcctccca agcactactt tgtaatacat tggctaattc atgttctttg
    15841 acaaactgat catattctaa tgtgggaatg ccaatttgat aacggtacat ttcctactct
    15901 ctttcctcca gtattttatt actattctac tactttcgtt tgaaaagtct agtgaaaaca
    15961 tattttattt tagttctact ccccctatgc tgaagttcaa actaagtcag tctctcttct
    16021 aatttgaaat caattggtag ggttgttaaa aaaacttcca attgtttttc ccagtagtac
    16081 cactcgtgag ttccagcact atggctatag gtcacatcaa aacctagttt tttgagattt
    16141 ttcactgcga gattattggc ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt
    16201 ttggtctttt tatccgattt tttagccaga ctttcaagag aatagggact agttgtccag
    16261 tctctaatct ctccaaaaac acctctccag taggctggac ttcccagatt ttgactttca
    16321 ggagaaaagt tttgaaagct gagggcacct gaaaaactag ctgcatgaga aaaacgattt
    16381 gtcgtaagag ccagtttgaa gcagccgtag cctcccatag aaagaccagc gataaaggtc
    16441 ttttcacgct tgctagtcat attagggaag aagcgtttca gaacctgtgg caattcctct
    16501 gctagagccg tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc attgctggta
    16561 ttgggcataa caacgatgag attagttcct cgaagcaagc gttctacatt ggtccgctta
    16621 agccaactat tatgattgcc agacatcccg tgcaaaaggt acaagacggg aatatcttca
    16681 cactctggtt cttccactcg attggcatca gggtagagga cattcacccc ccactccata
    16741 tccaatactt gtgagtaata ctcgattttc attactgcca tgattttctc cttctatttt
    16801 tctataagaa aaagccgaaa ctcgactttc tctctgttta tttcaacgat tattttgctt
    16861 ccatgactac tggtaaaata gctggacgac gcttggtttg gtcaaagaga tacttggtca
    16921 aattatctcg aaccttccct ttaagatctg cccagtcaaa gtcatctcct tgaagatact
    16981 cttctaccgt ttggttaatc aattctgaac tttcacggag aatatcgcga ctcttcttga
    17041 gataaacaaa tccacgcgtg tgaacacgag ccctagccac aattttcttc tcacgacggt
    17101 tgactgtaat agccacgatg aaaattccat cctctgacaa gaccttacgg tcacgaagaa
    17161 caacatttcc aacatcacca atggcattcc catcaatcaa gatatctcct gctgaaaccg
    17221 atccagctgg aacaaagtct ccattctcgt aagccatggt cgtccccttt ttaggaatga
    17281 agatgcgttc tggcaacatc ccaactgcca tggcagcctt agcgtgagca tccaactcac
    17341 gatactcccc ttggacaggg aagaggtact taggttgcaa aagattgatc atcagctgca
    17401 aatcacgcac atttccgtgc cctgatacat gtaaactttg ggtaatcaat ttgacaaccc
    17461 cacctgcctg ataaatcata ttttccacac gcgcaacaaa ggcttcttta gcaatagacg
    17521 gagccgtagc aatatagact aggtccccat ccttgatttc tacataacga tggcgaccaa
    17581 tcgacatctt acgaagtcca ttgataggct cacccatacg acctgtctca agaataatca
    17641 actcatggtc ttcaaagcga gacatatctt taggcttaat caaaagaatt tcgttggcta
    17701 aagacaactt cttaagacga atcgctgtgc ggacgatatt ttcaatatca aatcctgtca
    17761 agacgatacg tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat
    17821 tactggaaac agctgcaacg atgatacgac cttcccagtc agcaatagtt tgggtaattt
    17881 catccctaac ttcactttca ctagccacct gaatattgct gtctgcattg gccgaatcac
    17941 tgaggagagc caggacgccg tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat
    18001 aagattcact agccgtttgg tcaaatttga agtcacctgt ataaacgatg cttccttccg
    18061 atgtcttcaa gacaattccc agactctctg gaacggagta agtcgtaggg aagaaggaaa
    18121 ccactgtccc accaaaatca atctccgtat tctcatcaat gacatggaaa tcattaaatt
    18181 tcttaacggc atcatttcct ttgacaaaga gctttgccaa ctcaatggtc aactcagacc
    18241 caaatacagg aactttagcc tctgccaaga gatacggtag agcaccaatg gcatccgcat
    18301 gcccgtgggt caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt
    18361 ttggaatcac cacatcgacc cctaattgtt cattttcagg atattttaac cctacattca
    18421 aaacaaaaat ggactctcca atttcagcaa tgtacatatt ttttccattc tcacgcacac
    18481 caccaagtgt tgttaaactg atattactca tttttcctcc aaaatcttag tttatcttga
    18541 ttatagggca attctaccct cttattctaa aagttctgat actttcagcc gaatcttttc
    18601 ctaccattat accatttttt tgatgatttt caaaatgaag gtctgttttc aaaaaagagt
    18661 tgatttccca actctttcct aacttctact ctttttccat caaaaaatca taaatttctt
    18721 gcaccgtacc cagcgccatc atttcttggt ctttaacggt ttgtttgaga ttttggtaaa
    18781 tttgactttc tcctatctcc cgctttggcg cctctttatt gactgtcatc acaccatctt
    18841 ttatcgtcac aaagcctagt tcttcaaata cttgaatcat cttgaccagc aagatttgtt
    18901 gaatattaag atatgcagcc aaatctttca gcttgtagcg aatatcaaac tctgggaact
    18961 ggtaaatagt cttgtacaat ttggcaaact gatctctagt cccataacct gtcagataat
    19021 aagccttgtc aatatcattt ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg
    19081 tcttcagctg agtaatatcc tctggaatgt tttttacgac aacagcttca ctagccgcaa
    19141 gatttggcag ttctccagga aaatccaaga ctggaacacc ttctggcaag actgcatttt
    19201 ttccacgaat gttaaaaagt tgaacacctt ccactcgcgc atccaccatc atcaactgga
    19261 gggcagtttg gccattccat tggttgacag acaatttaac cgctaactct agattcttgg
    19321 tttgagaaaa ctctgtcgcc catctgcctt gaccaaaggc taccacttca aaactcgcct
    19381 cacccttgga aattttcagc tttagatggg cattacctgc ccccatagta cgagcacttt
    19441 cgacctgaaa attcttgata taaaaaatag gtttctgatt atccattcca aaaggagcta
    19501 aacgttcaaa acttttgacc gtttccaagc taagtgcctc caaatccaac tcttcatcta
    19561 ggtttaactt attcttgcca ccagcatctg cacctttttc acgaacataa tcttccaaaa
    19621 cctgagataa atctgagagt tgctcaactt ccagcgtcat acccgctgca cctgcatgac
    19681 ctccaaaggc gatgaagagg tctcgatggg gatccagagc ttcaaaaata tcgaccgctt
    19741 ccacactacg agcactgccc ttggcacgac cgtcttctat attaagaaca atgactgtct
    19801 gtcccaattc ttccaataaa cgaccagcca cgattcctag aaccccagga ttccagcctt
    19861 ccttggccaa gacctgaacc ttcttctcag gatccaccat ggtcttggct tcttcataga
    19921 tagactgaac gatttccttg cgctcttcgt ttttctggtg aatcataagg gcaatctcat
    19981 gcgcttcctc atcatcaaat ccagtcaaca aatcaatggc aggattggga tcatccaagc
    20041 gacccaaggc attcaaacga ggagcaatct ggaaaccaac cgtttcttct gttacttcgt
    20101 tggcagcaat cccagccatg tccagcattt cttgcagacc aatgcgctgg gtatgaccca
    20161 acatttccag accatattga actaagatac gattttcatc cgtcagactc accatatctg
    20221 caatagttcc aatagcgacc aaatcaagca attccacttg cacttcttct aacagggcac
    20281 aagccaactt gaaagcaact ccacaaccag ccaaatattt aaaaggataa tccgcatctg
    20341 gatgttcagg atggacaata gcataagcat ctggcagggt ttcaggcatg gaatgatggt
    20401 ctgtcacaat gacatctact cccatagact gagccaatgc aatagcctca tgaccagcaa
    20461 ccccattgtc caccgtcaca atcaaggaaa tcccttcttg ctcgataaag tatttataaa
    20521 cactagcatt agggccatag ccatcggtaa aacgatttgg caggtaaact cggcactcag
    20581 caccaagttg ttccaaactt tccttcacaa tagaagccga agtcatgcca tccgcatcat
    20641 agtctccata aacaagaata ttttcccctt cttcaatagc ctgacgaatc cgctccactg
    20701 ccttgtccat atcatggagc agataagcat catgtaagtc ctccaaggaa ggttctaaaa
    20761 acttcttcag actttcttgg ttctgaatcc ctctctcaaa caataaccga gccacctcag
    20821 gacccagtcc agccttcttg gctatctttg taaaatccgc atcttctacc tgcagggcaa
    20881 actgccattc ataagtaggt gttatcaaaa agacatccac tctttctaag aattctattg
    20941 cttcattata acatgattta gacgttttct ctatccagat tgctttttta taacatttta
    21001 tagtatattg aaactagaat agtacacctc tacttctaaa atattgttag aaatcgattt
    21061 gactgtcccg atcgattttt cctgttctta tttcactata gtgaattttt tcagatatga
    21121 tttgacaaga acattctttt attgtagaac cgtgttataa aatataacac aatagagatc
    21181 tctcatggct ttagtagaat ttaaaaacgt cgaaaaatat tacggagact accacgcatt
    21241 ccgcaacatc aatctccgta caaagctgtg ttagaaaacg taacgcttgc acccattgaa
    21301 gttctaggaa ttgataaaaa agaagctgaa aaaaccgccc aaaaatatct ggaatttgta
    21361 aatatgtggg acaagaaaga ttcctatccc gccatgctat ctggtggaca aaaacagcgg
    21421 atcgccatcg ctcgtggtct tgctatgcat ccggaactcc tcctctttga tgaaccaaca
    21481 tctgctcttg atcctgagac tatcggagat gttctagcag ttatgcagaa actggcgcat
    21541 gatgggatga acatgatcat cgttacccac gaaatgggct ttgctcgaga ggttgcggac
    21601 cgcattatct ttatggccga cggagaagtt ttagtagata cgacagatgt cgataacttt
    21661 tttgacaatc caagcgaacc tcgtgcccaa caattcctca gcaaaattat caaccacgaa
    21721 agtgacaaag tcaaataagg aggcgcctat gaaaaaaaaa ttctttttat cagcattatt
    21781 gattagcctt ttcagccttg ctgctgccaa accagtccag gctgatacaa gtatcgcaga
    21841 cattcaaaaa agaggcgaac tggttgtcgg tgtcaaacaa gacgttccca attttggtta
    21901 caaagatccc aagaccggta cttattctgg tatcgaaacc gacttggcca agatggtagc
    21961 tgatgaactc aaggtcaaga ttcgctatgt gccggttaca gcacaaaccc gcggccccct
    22021 tctagacaat gaacaggtcg atatggatat cgcgaccttt accatcacgg acgaacgcaa
    22081 aaaactctac aactttacca gtccctacta cacagacgct tctggatttt tggtcaataa
    22141 atctgccaaa atcaaaaaga ttgaggacct aaacggcaaa accatcggag tcgcccaagg
    22201 ttctatcacc caacgcctga ttactgaact gggtaaaaag aaaggtctga agtttaaatt
    22261 cgtcgaactt ggttcctacc cagaattgat tacttccctg cacgctcatc gtatcgatac
    22321 cttttccgtt gaccgctcta ttctatctgg ctacactagt aaacggacag cactactaga
    22381 tgatagtttc aagccatctg actacggtat tgttaccaag aaatcaaata cagagctcaa
    22441 cgactatctt gataacttgg ttactaaatg gagcaaggat ggtagtttgc agaaacttta
    22501 tgaccgttac aagctcaaac catctagcca tactgcagat taaggaggac accccatgac
    22561 agatttatca tcttggacag cctattttca ggattttgga caatttttca atggtttcct
    22621 cttcaccctt gccctagcgg ttggttcctt tatcctcgcc atggtcttag gaatcttctt
    22681 tggtgccatg tcaaccagta aacgtccaat tttacgcatt ttagctcgca tctttgttga
    22741 attttaccaa aatactcctc tcttggtgca gtttgttatt gttttttatg gcctacctct
    22801 tatcagtgac catatcatca tgattccaat ttattggaca gccgttctct gcgtgggact
    22861 ctatcacggc gcttatatcg ctgaggttat tcgttcaggg attcagtcta ttcctagtgg
    22921 tcagatggag gccgccttgt cgcaaggttt tacctatatc agtgccatgc gcttgattac
    22981 cttgcctcag gccttctgca tcattctacc tccattgacc aaccaaattg ttaacctcat
    23041 caagaacacc tctactgtag ctatcatctc tggagtagac ttgatgtttg tgactaagtc
    23101 ttggtcggct ctcaacggaa actatatccc agccttttta ggtgctgctc ttctctactt
    23161 tgccctatgc ttccctgttg cccagtttgg tcgcaagatg gagcaagcca acaaaaaagc
    23221 ctattcactt taggaggtta ctatggaatc tattttagaa gttttaaccc cagataacct
    23281 agtctttatc tttaaaggat ttggcttgac cctctatatt tctctgattg ccatcatcct
    23341 ctctactatc atcggtacgg tgctagctgt catgagaaat ggcaaaaatc ctatcttacg
    23401 cattatttcc agtatttata tcgagtttgt gcgcaacgtt cccaaccttc tctggatttt
    23461 tactatcttt ttggtgttca aaatgaagtc cacaccagca ggtattacag cctttactct
    23521 ctttacatca gcagccttgg ctgagattat tcgaggcggt ctcaatgccg tagacaaggg
    23581 acaatacgaa gcaggaatgt cacaaggctt cacctcagcc caaatcctct actacatcat
    23641 tctcccacaa gccatccgca aaatgctacc agccatcatt tctcagtttg ttcccgtgat
    23701 taaggatacc agtctcctct actctgttat cgccctacaa gaactctttg gagccagcca
    23761 aattctcatg ggccgttatt tcgaaccaga gcaggtcttc agtctttaca tcctgattgc
    23821 cctcatctac ttcagcttta acctagcaat ttctagcctg tctcatatgc tagccaaacg
    23881 ttggcaacaa gctgcagaat aatactcttc gaaaatctct tcaaaccacg tctgcttcac
    23941 cttgccgtat atatgttact gacttcgtca gttctatcca caacctcaaa acggtgtttt
    24001 gagcagcctg cggctagctt cctagtttgc tctttgattt tcattgagta taaacagcca
    24061 ctctccagtt caattggaga gtttttttga tgagagtaga tatttataga cctcaatttg
    24121 acaccataca ttttctatga taaaatgtaa caaatttatt tacaacaaat cgaaatctaa
    24181 atgaaatgga attttctatg aaatcaatca aaggactact ctttatcata gctagtttta
    24241 tcttgactct tttgacttgg atgaacactt ctccccaatt catgattcca ggactagctt
    24301 taacaagcct atctctgact tttatcctag ccactcgtct cccactacta gaaagctggt
    24361 ttcacggttt ggagaaggtc tacaccgtcc acaaattcac agcctttctc tccatcatcc
    24421 tactaatctt tcataacttt agtatgggcg gtttgtgggg ctctcgctta gctgctcagt
    24481 ttggcaatct tgccatctat atctttgcca gcatcatcct tgtcgcctat ttaggcaaat
    24541 acatccaata cgaagcttgg cgatggattc accgcctggt ttacctagcc tatattttag
    24601 gactctttca catctacatg ataatgggca atcgtctcct tacatttaat cttctaagtt
    24661 ttcttgttgg tagctatgcc cttttaggct tactagctgg tttttatatc atttttctat
    24721 atcaaaagat ttccttcccc tatctaggga aaattaccca tctcaaacgc ttaaatcacg
    24781 atactagaga aattcaaatc catcttagca gacctttcaa ctatcaatca ggacaatttg
    24841 cctttctaaa gattttccaa gaaggctttg aaagtgctcc gcatcccttt tctatctcag
    24901 gaggtcatgg tcaaactctt tactttactg ttaaaaattc aggcgaccat accaagaata
    24961 tctatgataa tcttcaagcc ggcagcaaag taaccctaga cagagcttac ggacacatga
    25021 tcatagaaga aggacgagaa aatcaggttt ggattgctgg aggtattggg atcaccccct
    25081 tcatctctta catccgtgaa catcctattt tagataaacg ggttcacttc tactatagct
    25141 tccgtggaga agaaaatgca gtctaccttg atttactccg tgactatgct cagaaaaatc
    25201 ctaattttga actccatcta atcgacagta cgaaagacgg ctatcttaat tttgaacaaa
    25261 aagaagtgcc cgaacatgca accgtctata tgtgtagtcc tatttctatg atgaaggcac
    25321 ttgccaaaca gattaagaaa caaaatccaa aaacagagct tatttacgaa ggattcaagt
    25381 tcaaataagt aatcatactc tcctgggaaa tcccaggaga gttttttata gccaaatgaa
    25441 ataagacagg aacgatggaa ttttggcatt caaatcaatt gataagacta ttttatagtg
    25501 gagtgaaata ggatacgaac aaattgatta ggaaaatcaa atgaatttat agaaatcttt
    25561 tagcagttat gttatcctat tctagtttca aaacgctata gaagcagcat tgtgctagtc
    25621 tagattcagt ttactatact aaaacgagta gcttgaaatc aaaaaaccca ccctcacagg
    25681 caggttttat ctgtattatt cagctagatt atgctttacc ttctgaaccg aatacgtcga
    25741 tacgttcttc aaccgatgct tggatagctt ttacaccgtc agccaagaat ttacgtgggt
    25801 cgaagagttt tttcttgtcg tattctgctt cgtttgcttc gtagtcacga gcaaatttac
    25861 gagttgcgtt agcgaatgcg atttggcatt ctgtgttaac gttaactttg gcaacaccaa
    25921 gtttgatagc tgcttggatt tgctcatcag gaatacctga tccaccgtgc aatacgattg
    25981 ggaatcctgg aagagcttct gtcaattttt gcaagtggtc aaggtcaaga ccttcccagt
    26041 ttactgggta aggaccgtgg atgttaccga taccagctgc caagaagtcg ataccagttt
    26101 caaccattgc tttagcgtct tcgattggag ccaattcacc tttaccgatg attccgtctt
    26161 cttcaccacc gatagtacca acttcagctt ctactgagat acctttagcg tgtgcttttt
    26221 caacaacttc tttagccaat ttaaggtttt cttcaactgg aaggtgtgaa ccgtcaaaca
    26281 tgattgaagt ataaccaact tcgatacact caagtgcatc ttcgtagtga ccgtggtcaa
    26341 ggtggatagc tactggtaca gtgataccca ttgattcaac aaggttagcg atcaagttgc
    26401 gagcaacttt gtaaccaccc atgtatttag cagcacccat tgaagtttgg atcaaaactg
    26461 gagctttttt agcttctgct gcgcgcaaga tagcttgagt ccactcaagg ttgtttgtgt
    26521 taaatccacc aactgcataa ccgttgtcac gggctgcttg gacaaatttt tctgctgaaa
    26581 cgattgccat tttatcaggc ctcctgtata tttttatggg tcatcccatt tacattgttc
    26641 attttatcac tttttgccaa aaaaatctag tttttcccgc agtttcgatt gattttcttc
    26701 taactccatc tatgtaaacc ctttctctcc ctagtcttgg gcgacttttg gaaaagctat
    26761 aaagaaggtt aaacgattct cctccatctc gaaacgataa gctaattttt catgttctaa
    26821 tagactctta accacaaaga gccccatacc agaccccttg accttgcgac tggcattgtc
    26881 agaaaaagac tgggctagtt tttcttgttc ctctgagcta cagctatttt cgataaaaag
    26941 ttctccttct ctttctccaa ttcgaactaa gccacctgga acagagtgct taatggcatt
    27001 gctgatgaga ttagaaagaa tcaacttcat aactgatggg tttagataag cctgctgatg
    27061 ggtcaaacta ttgtctatct ggagctctct ttccttggct agcaaggcat aatctttgac
    27121 cagattttgc gtcatctgga ggaggtcaat tgtttcccta tcatctcgca attcctgcac
    27181 agaagagagg gaaagtatct gcagaacatg gtgattgagt tcatccacaa tccccaaggc
    27241 aactcccaga tactggtctc tatccttata acgaccgata ttctctctca tattttcgat
    27301 taggattttc aaactagcca gcggtgtttt caattcatga gaagctcctc gtaggaattc
    27361 gaccttcatc ttctccagct ggagaatggc ttcattcttt tcatgcaagt ccgcaataac
    27421 agtcaagaga tgctggtaga ggctattgat ttgttccttg agattaccta tctcatcctt
    27481 agaatccacg cgcaatcgca cttgggaatc caggtccatc atccgacggg tcacccgctt
    27541 gatttccaaa atcggtgcaa caatagtccg ggcgtagatg taggccacca agagggaaat
    27601 cagaaaggag gccagcaagg tatagggaag aaactggaga ctgatttgct ccgcttcctt
    27661 ttgtaaatcc atggaagcta gaaactggag aatcatagta ccaccgtctt gcgttttcac
    27721 ctcgcgctcc tcaataaaga gagaggttgt ctggcggtct gtgtccagag gaagactgtc
    27781 cttgacttct aacttgtcct cggtcatctc acctttgacg gtccccttga tatcactagt
    27841 ctgggaatac aagtctaaca cttgctcgat actctgccta tctttccctt ctagggactg
    27901 ggcaatggct gttgcctttt gaccaatggt ttcctgacga tgactcagat aagtcgaagg
    27961 aaaaagaaaa taaatagcta aatgaaggca gataaccaga acactaaata tcgagaaggt
    28021 atagataaat atctttgcaa ataaacctgt tcgtttcatt ttcgctccaa tttataacca
    28081 acattgcgca cagtgaggat acaatccaag tctagctttt tccgcaattc cttgatataa
    28141 acatcaataa cacggtcaaa gggaacctca tctgtcgctt tccagacggc atcgataatc
    28201 tgagaccgag tcaaggcccg gccttcattt ttcactagat agtccagaat ttccaactct
    28261 ttggcattga taggcacttc ttgacctgcg aggcttgcac tgtagctttc aaagtccacc
    28321 ttggtatcct tgtaagaaaa gattcgtcct gtatcgtagt agcgcttgaa aatcgcgtcc
    28381 accctcactt ttaagaggga gagagagaaa ggtttttcca gatagccatc tgccaaagag
    28441 gcaaaggcac tcatcttgta ttcctcatcc tgaaaagctg tcaacatcaa gacaggaacc
    28501 tgactggttt tacgaatctc agctaggact tctaagccgt taagcttggg catctggata
    28561 tccagtaaaa ccagggccac ctcatagcta gaaaattgct ccagagcttc ctgaccgtcc
    28621 gctgcctcaa tagtttcata gccacaatcc gtcaaataat cactgacccc ctcacggatc
    28681 atctcttcat cttctacaat taaaattttc atactttaac tgctctctat tttttatttt
    28741 tcttagaata aatacctact ctattttcta ttatagtctc ttgctggcct tttgtctgta
    28801 agcaactgat cactagataa aacgttgtga aattcctttc tcataaattc cataacttta
    28861 gtatattata tttaagcact aaagtacaaa gaaagcaact gaaagcaatg attttcacca
    28921 ctgctttcag atttattttg aattgttaaa tagctattcc tatccactat tcttgaatag
    28981 aaacacaaga tgcaatcttt attccagact cattttttca aatttattca ccatccagca
    29041 agagctcttt tggttgtttt ctaaggagat tgcttgaagc aagcgccata acgagaacca
    29101 ctagaaccaa ggcaaggaca aaaatgatga taaagtctga tgtctgaatg gaaatgtcta
    29161 ggctcgacaa ggtcttgcta aagccatcta cttctgcacc gccaccaagg ttagaggctt
    29221 gagccgcctt actagcctgt ttggcaacac ctgaagtcac attggcaagg acagtgtttc
    29281 caattgcacg ggcagtgtaa ttagctagga agtaagcaga aactagagca gggatagcaa
    29341 tcaagataga ttcggtgatg aattgaccca agatacttgc ctgcttgagg ccgatagaga
    29401 ggagaattcc cacttccttg cgacgggcgt tgatccaaag gctgagcaag agggcaagga
    29461 ggagaactga gaagctcaag ctaccccaga agaggaggtt ggccatcttg tacataccag
    29521 agatagattg ctcaagagct gggtagttag aggagctctt gacgagtgtg tagctcttcc
    29581 agttgatacc actgatgcca ttcaactctt tcataacatc atccaagttc ttgtctgctg
    29641 ttacaaagaa ggttgcgtcc ccataaatgg ctgtgtcttc tgtgtatcca taaagttttg
    29701 cagcagtgtg aatgtctgta atagctgtgt tttcgtaaag ttcttgtgag taggttactg
    29761 ctgacttatt atgaccatca aagagtccct tgattgtcac ttcaactgtt tccttggctc
    29821 ctttttcatt atctgcatcg tagatattag agtccagttt aaccttgtcc cctactttcc
    29881 agccgtgttt ggctgccaag tccttgtgca agaggatttt atccttgtcg tcgttggtta
    29941 agtgctctcc ttcgactagt ttataagaac cagagacaaa cttatcttct ttagaggagt
    30001 cattgacacc tgtaatcatc aagctacttc caaaacgctt ggcacgatca gcagtgagat
    30061 tcttcttggt ttctggcgtt tcaatcaggt catatccagt caaatctccg atagcgttga
    30121 tacgtttgac ataagactcg atggccttgt tttcggtgat ttttttgatg tcttcaccct
    30181 tgatattccc agcaccacga ggcgttcctt ggttgacgcg acgattgatt tgcatggaga
    30241 agctattggt gatattttta aaggtctcct gagaagcctt ggcagtagct cccttgattg
    30301 acaagccgac caaactcaag ctcgccatga ggagaataat caggaagatg acaatcgatt
    30361 tgaaaaactt ccttgtaaca taggcaaatg cgttgtgtaa catagattcc ctttctagat
    30421 tttgttttaa tcattctatc aaaataagct caaattattt actagtattg cgcgtttcag
    30481 tcagtttctt atcctttaat tcaagtgtaa tatctgacgc ttgtgccact tctttactgt
    30541 gagttacgac aatcacacat ttacctgttt tctgggcaag tgatttgagt agttcgacaa
    30601 tatctccagc agttttagga tccagatttc ctgttggctc atcagctaga ataactggag
    30661 cttctgagac caaactgcga gcaatggcaa cacgttgctg ttgaccacct gataactgga
    30721 gaacattccg cttgatctgg ctttcatcca aaccaagctc aagaagtgta ttcttgcttg
    30781 cctttttgtt gaccaatcgg atattttcca gcggagaaag ataatctatc aagttataat
    30841 tttgaaagac cagggaaata tggtgcatgc gatggtaaga atagcccttc ttacgaatat
    30901 cctctccttg aaaaaggata gaaccttcaa caggactatc tagaccagca agtagggaca
    30961 agagtgtgga ttttcctgct cctgactccc caataatact gtaaaatttt ccgggttcaa
    31021 aattataatc gatctgatat aggactgctt cagcagtatt cttataacgg taggtaacat
    31081 cttgtaattg taataaagtc atgatttctc cttcttaact aatagatgat aaaatttctt
    31141 tcggtgattt tctaaataag aataggaaac aaagggctac agataagcaa ctaagcagaa
    31201 ctagaaaaac ataggattct gcaaaagata agatactagt tgataaactg cttgctttgg
    31261 ctagtgtatc ttgtaagctt gcctgatctc cacttgctag tagagtttgg agtaggtaag
    31321 ttgtgattcc gtttcctgca acaaatgctg gaagcaaagc tccaagagat accaaaacta
    31381 cctctaaaca gaattgtagg aagatcgagc tcttgccttt tccaagtgca agtaaaatcc
    31441 ccacttcata gacccgttct ctcaaccaga gagacaaaac cagaattaag gctccagctc
    31501 ctgctatcaa catcccataa aggaagatgg tcaggaaggt ttggaaagtt gcaactgagt
    31561 ctttgatttg ttcaaaagcc ttgttttcct tttcgacttg gtagccttga ttttccaagg
    31621 ccaagttttc tacctgcttc atgagtccgt ccatttcctt aggattttct acatagaagc
    31681 gtgctgcact gacttgagct tcactattgc ccaaaagggt ttggctactt tcatagtctg
    31741 taaagacttg attttcactg aagtcagaag acaagcctgt gaatttctct tgttttttac
    31801 cagaaaagat gccgataatc tcaaactcta ctgtttgtcc ttttccagat tcagactgac
    31861 cagcatccaa gccaatcttg tcatgaagtg aaagaccgtt cttcttagcc aattcttcgt
    31921 ggataaggat tttcttggaa tccccttttt gaaggtgtcg cccttctttt agattgaaag
    31981 ccgaactggt aaaggttaca tccttggatg aatcctcaag agccgttaag ctaaccaagt
    32041 tattgtctgc agctgataaa tcatcacgct ccacgctctg ctcgccagtc actgcttcct
    32101 tgtcttttag ttttgcgacc gtctcaagtt caggagagac attttccagc cccttaatct
    32161 tgcttacaga tgctaggtct gacaacttga atgtctgacc attctctatc ttcttaatag
    32221 aaaaagatgt attgagtgat ttataaagat tgctttctac tgttttgttg gacttcatca
    32281 gagtcaaaca ggctgaaatt ccggccaata agaccaataa aatcagaaat aaaataaaac
    32341 ttctcagtcg ctttctgctg acataagccc aagatctttg gattggattc atttgtcacc
    32401 tccatatttg taagactatt ataaaaccca aatatgaaat gtttatgaaa tacgaaaaaa
    32461 aaa
//
LOCUS       DAVEHY010000024        31304 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVEHY010000024 DAVEHY010000000
VERSION     DAVEHY010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.024"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(89..2086)
                     /gene="metG"
                     /locus_tag="VUZ44_001365"
     CDS             complement(89..2086)
                     /gene="metG"
                     /locus_tag="VUZ44_001365"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU0320275.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPEGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2210..3469)
                     /locus_tag="VUZ44_001366"
     CDS             complement(2210..3469)
                     /locus_tag="VUZ44_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320276.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3471..4172)
                     /locus_tag="VUZ44_001367"
     CDS             complement(3471..4172)
                     /locus_tag="VUZ44_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320277.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4156..5355)
                     /locus_tag="VUZ44_001368"
     CDS             complement(4156..5355)
                     /locus_tag="VUZ44_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU0320278.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKISEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KTDEATN"
     gene            5641..6987
                     /gene="gor"
                     /locus_tag="VUZ44_001369"
     CDS             5641..6987
                     /gene="gor"
                     /locus_tag="VUZ44_001369"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU0320279.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            7184..7720
                     /locus_tag="VUZ44_001370"
     CDS             7184..7720
                     /locus_tag="VUZ44_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU0320280.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7771..7857
                     /locus_tag="VUZ44_001371"
                     /pseudo
     CDS             7771..7857
                     /locus_tag="VUZ44_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7926..8141)
                     /locus_tag="VUZ44_001372"
     CDS             complement(7926..8141)
                     /locus_tag="VUZ44_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU0320281.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8239..8559
                     /locus_tag="VUZ44_001373"
     CDS             8239..8559
                     /locus_tag="VUZ44_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320282.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8589..8927)
                     /locus_tag="VUZ44_001374"
     CDS             complement(8589..8927)
                     /locus_tag="VUZ44_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320283.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8939..9658)
                     /gene="trmD"
                     /locus_tag="VUZ44_001375"
     CDS             complement(8939..9658)
                     /gene="trmD"
                     /locus_tag="VUZ44_001375"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU0320284.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9648..10166)
                     /gene="rimM"
                     /locus_tag="VUZ44_001376"
     CDS             complement(9648..10166)
                     /gene="rimM"
                     /locus_tag="VUZ44_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU0320285.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10197..10985)
                     /locus_tag="VUZ44_001377"
     CDS             complement(10197..10985)
                     /locus_tag="VUZ44_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU0320286.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEENFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11562..11801)
                     /locus_tag="VUZ44_001378"
     CDS             complement(11562..11801)
                     /locus_tag="VUZ44_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU0320287.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(11821..12093)
                     /gene="rpsP"
                     /locus_tag="VUZ44_001379"
     CDS             complement(11821..12093)
                     /gene="rpsP"
                     /locus_tag="VUZ44_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU0320288.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            12263..12480
                     /locus_tag="VUZ44_001380"
                     /pseudo
     CDS             12263..12480
                     /locus_tag="VUZ44_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12959..13180
                     /locus_tag="VUZ44_001381"
     CDS             12959..13180
                     /locus_tag="VUZ44_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320289.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            13264..14067
                     /locus_tag="VUZ44_001382"
     CDS             13264..14067
                     /locus_tag="VUZ44_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU0320290.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(14124..15665)
                     /locus_tag="VUZ44_001383"
     CDS             complement(14124..15665)
                     /locus_tag="VUZ44_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU0320291.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLTERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     NRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(15667..16149)
                     /locus_tag="VUZ44_001384"
     CDS             complement(15667..16149)
                     /locus_tag="VUZ44_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU0320292.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            complement(16149..17234)
                     /gene="rlmN"
                     /locus_tag="VUZ44_001385"
     CDS             complement(16149..17234)
                     /gene="rlmN"
                     /locus_tag="VUZ44_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU0320293.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYTPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(17255..17785)
                     /locus_tag="VUZ44_001386"
     CDS             complement(17255..17785)
                     /locus_tag="VUZ44_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU0320294.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(17942..18547)
                     /locus_tag="VUZ44_001387"
     CDS             complement(17942..18547)
                     /locus_tag="VUZ44_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU0320295.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(18720..19757)
                     /locus_tag="VUZ44_001388"
     CDS             complement(18720..19757)
                     /locus_tag="VUZ44_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU0320296.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(19791..20726)
                     /locus_tag="VUZ44_001389"
     CDS             complement(19791..20726)
                     /locus_tag="VUZ44_001389"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU0320297.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(21279..22469)
                     /locus_tag="VUZ44_001390"
     CDS             complement(21279..22469)
                     /locus_tag="VUZ44_001390"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU0320298.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(22846..24189)
                     /locus_tag="VUZ44_001391"
     CDS             complement(22846..24189)
                     /locus_tag="VUZ44_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU0320299.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(24329..25144)
                     /locus_tag="VUZ44_001392"
     CDS             complement(24329..25144)
                     /locus_tag="VUZ44_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU0320300.1"
                     /translation="MKFLTLNTHSWMEKEAKEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVVLAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            complement(25196..27376)
                     /locus_tag="VUZ44_001393"
     CDS             complement(25196..27376)
                     /locus_tag="VUZ44_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU0320301.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(27662..28588)
                     /locus_tag="VUZ44_001394"
     CDS             complement(27662..28588)
                     /locus_tag="VUZ44_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320302.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(28581..29273)
                     /gene="ftsE"
                     /locus_tag="VUZ44_001395"
     CDS             complement(28581..29273)
                     /gene="ftsE"
                     /locus_tag="VUZ44_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU0320303.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(29291..30386)
                     /gene="prfB"
                     /locus_tag="VUZ44_001396"
     CDS             complement(join(29291..30313,30315..30386))
                     /gene="prfB"
                     /locus_tag="VUZ44_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU0320304.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQGEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFISVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(30494..31150)
                     /locus_tag="VUZ44_001397"
     CDS             complement(30494..31150)
                     /locus_tag="VUZ44_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU0320305.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
BASE COUNT         9194 a         6850 c         5671 g         9589 t
ORIGIN      
        1 acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaat aaaaaaacag
       61 aactagcctg aactagtcct gtctactttt acccaatcac acttccattt ggtacagctg
      121 gatcaactgt gagaagggtt aatttgccat catgttcagc tgagagaatc ataccctggc
      181 tgacatattt tttcatcatt ttacgtggtt tgaggttagc aatgatttga actttcttgc
      241 cgaccaattc ttgttcattt ggatagtatt ttgcaattcc tgaaagaatc tgacgatctt
      301 ctccatcacc agcatccaag cggaattgaa gcaacttatc tgaaccttct actttagaca
      361 cttctttgac ttctgcgaca cggatttcaa ccttgtcaaa gtcttcaaac ttgatttcat
      421 ccttgtttag tttgagctca acttcgtccg gattccattc tttttcgact gctggtttat
      481 tgccttccat ttgttccttg atataggcga tttcttcttc catatttaga cgtggaaaga
      541 taggtgttcc tttggcaact acagtcacat ctgctgggaa gtcagccaaa ctcaagtttt
      601 caagactaga aacttcttcc aaaccaagtt gagtcaaaac tgcacgacta gtttccatca
      661 taaatggttc aatcaagtga gcaactacac gaatgctggc tgccaagtgg ctcatgacac
      721 ttgccaattg gtcacgaaga gcttcatcct tggccaagac ccatggtgcg gtctcatcga
      781 tgtatttatt ggtacgagag atcagagtcc agactgcttc aagcgcacgt ggatagtcaa
      841 ctgcttccat gtgtgtatgg aagtctgcga ttgattgttc tgcaacctca gcaagaacat
      901 gatcaaattc agtcacacct tctacatagg cagggatttg tccatcaaag tacttattaa
      961 tcatggaaac cgtacggtta aggaggttcc caaggtcatt agccaattca tagttgatac
     1021 ggccgacata gtcttcagga gtaaaggttc cgtctgaacc aactggaagg ttacgcatga
     1081 ggtagtaacg aagtggatct agtccataac gctctaccaa catttcaggg taaacgacat
     1141 tcccttttga cttagacatt tttccgtctt tcatgacaaa ccaaccatgg gcaatcaaac
     1201 gatcaggtaa tttaacatcc aacatcataa gaaggattgg ccagtagata gagtggaagc
     1261 gaaggatatc ttttcctacc atatggaaga ctgttccatt ccagaacttg tcaaagttac
     1321 catgttcgtc ttgagcgtag ccaagagctg tcgcatagtt aagaagggca tcaatccaaa
     1381 cgtagacaac gtgttttgga tttgatggga caggcactcc ccatgtaaag gttgtacgag
     1441 ataccgccaa atcttccaaa cctggctcga tgaagttgcg tagcatttca ttaaggcgac
     1501 cctctggcgt gataaattca ggatgagctt tgaaaaattc gaccaaacgg tcttggtatt
     1561 tgctaaggcg aaggaagtat gattcttcag aaacccattc aacctcatga cctgatggag
     1621 caataccacc agtcacattt ccagcttcat cacggaaaac ttctgccagc tggctttctg
     1681 taaagaattc ttcgtctgat actgaatacc aaccagagta ttcacccaag tagatatcat
     1741 cttgagcaag taagcgttca aagacttgtg cgacaacttt ttcatggtag tcatcagttg
     1801 tacggataaa tttatcgtat gagatatcta gtaattgcca gagttcttta actccaaccg
     1861 ccattccatc aacataggct tgaggtgtaa taccagcttc ttccgctttc tgctggattt
     1921 tctgaccatg ttcatcaaga cctgtcagat aaaatacatc gtagcccatc aggcgtttgt
     1981 aacgtgctag gacatcacat gcgatagttg tgtaggcaga accgatatga agtttcccag
     2041 atggatagta aatcggcgtt gtaatataaa aatttttttc agacataatt tttcctttcc
     2101 aggcaaatga aacctgtttt tctaacactt cattatatca catttttaat gaatttcgat
     2161 agggaaatcc atacaaaaac aagatagacg agtgtccatc ttgttgatct cattcataac
     2221 gaagggcttc aattggatca agtttcgatg ccttgttggc tggcaagact ccaaaaatca
     2281 taccaacact agccgaaact gcaagactaa atagggcaac tgggattgat actccaactt
     2341 ctataccttc tattaaacct tgcagtaaca aacctgctaa ggcagttaaa ccacttgcaa
     2401 ttgtcaagcc aattaagcca cctaacaagg tcaaaatcat ggattcaatc aaaaactgaa
     2461 ttaaaatatt ggcacgtgtt gcgcccaaag ccttacgaag accaatctca cgagtgcgct
     2521 ctgtcaccga aaccagcatg atgttcatga caccagttcc tccaacaaag agagaaatcc
     2581 ctgcgatgga actaataatc gtcgtcataa aactaaacga ttgttgaatt tctgcaaata
     2641 caacggactc atctgccacc tggtattctc cctgttgtaa gcctgcaagc tctgtcattt
     2701 ttcgtgccag ttctggaccc agagttgggg ttaaactggt atcattcact cgaaagacaa
     2761 tactagctat ttcatctata ttaaaattcg cagcaaggga gatattggta gtaataggca
     2821 agccaccaaa cccatatatt tttgaccttt tagcctccgg actagtataa accccaatga
     2881 cccggtaact aaatccattg acttctacaa ccttgttaat agcctcttga ggagattcaa
     2941 ataaactaat ggacaattcc tcatctagca aaatgacact tgcaaactct ttgaaatctt
     3001 gctctctcag actacgacct gcaataattt cattcttaac agcgtccatg taagttctgt
     3061 ttccacctgt caaattagca ttctcaacct ttttatcttg ataggtcaag atggcattcg
     3121 ttgaattggt tacatagtaa ctatccactc ccttcagttt agctgcctct tggacccagg
     3181 attcttgcgg ttttggcggt tcaacaggaa cttcctcttc ctttccagaa accgtaaaag
     3241 ctgattgttt ctgagtaaaa gacccatctt tacttttttt aggagagaaa aagacgctaa
     3301 tatttttctg agatttagtc atatctttat tgacttgacg agatagggaa tcacccaaag
     3361 ccataatcac aacaactgat gaaacaccga taataatccc aatcatagta agcaaagaac
     3421 gcatcttgtg agccatgata gatgaaaagg caaatttcag attctgcatc ttagttttcc
     3481 tcctttccta actgagcact gtcagacgaa atgaccccat cccgaatgac aatctgacgt
     3541 ttggcatagg cagcaatctc aggctcatgc gttaccatga taatggtttt tccttcttta
     3601 ttcaaatcaa ccaataattg cataatttgg ttacctgttt tggtatccaa ggctcctgtc
     3661 ggttcatccg ctaggataat agaaggattg tttaccaagg cacgcgcaat ggctacacgt
     3721 tgcttttgac caccagataa ttctgaaggt aaatggtgac tacgttctgt caattcaacc
     3781 ttgtctaaat attcctcagc caacttgcga cgttttgaag acgaaactcc tgcgtaaatc
     3841 aagggcaatt ctacattttg cagagcattg agcttcgata gaagaaagaa ctgctgaaag
     3901 acaaaaccga tttgttggtt acgaacctta gctagttgtt tttcaccaag cccagccact
     3961 tcttgacctt caagataata ttctccactg gttggtgtat ccaacatgcc aatcgtattc
     4021 atcagagtgg acttaccaga cccagatggt cccatgatgg ctacaaattc accctcattc
     4081 acttctagat tgatattttt gagaacctgc aattcttggt caccattacg gtagcttctg
     4141 aagatatttt ttagactaat tagttgcttc atcagtcttc acctcttttc cttcttccaa
     4201 ggaagatgtt ggattactga tgaccttagc accattcgtt aaaccagaag tgatttcttg
     4261 attttctgcg tcagcatttc ccaatgaaac ctcaactttt ttagcctttt gttgttcatc
     4321 cacaatccag acataatttt tactatcatc cattactaga ctgctaacag gaacaagaat
     4381 agccttagtt ttgcttttaa cctcaatgtt gacagaaaaa ccctgtttca aatcaccaac
     4441 ctcgcctgtc acatcaatag tataagggta tttagaacct gtattattcc cggctgctgg
     4501 actagctgct tcaccattgt ttttaggata gtcagaaata tagcttaatt tcccagtcca
     4561 ttttttatca ggatacactt tagaagtaaa gcttacttct tgacctacag aaaggttggc
     4621 tagattgtac tcagacaatt ctcccttgac ttgtaaattt tcattgctga caatatgaac
     4681 cataacttgg ctcgcccctg ttggagattt agaaacattg ctattgactt cgactacagt
     4741 tccctctagg gtactgagaa cagttgttgc atccaattga ctttgagcct tgcttaattg
     4801 cgccgcagca tctgcacgcg catcacgggc atcacccaat tgagcgtcaa tagaagcaac
     4861 agaatttcca gccactggag ttgggctttg caccgttgca tcttctcctc ctactggcgc
     4921 tggtaactgt ggagccggag ctgaagcggc ttcatttcgt gcttgattga gttcattgat
     4981 atgacgatct gccttagcta ctgctcgact agctgaatca taggccgcct gcgcttctga
     5041 actactgtac ttgactaaag cctgcccttc gctgatctta tcgcccacag aaacaaggat
     5101 ttcatctaaa tcacccttac tagcatcaaa ataaacatat tgttcatttt ttgctgttac
     5161 tgtccctgac aataaaacag aggatgccac gcttccttcc ttggcaacaa caagatgagt
     5221 aggctcatct tttacagcag tctgagaagg ttgtctaaag agtaaaatcc ccccggcacc
     5281 caatacaact acactcgcag caccgattgc tgcatacagt tgccactttt tagctttacc
     5341 attctttttc ttcataatga aactcctttt cttttttaca atactttgct attataccaa
     5401 atttccctcc agcaaacaat gcagttcaga tggaaataat ggcagttcag gattaaacaa
     5461 tcgttcggaa ttttgctttt ctattgtact agatatataa tacactatct tgacttattt
     5521 ggcaagcttt tttgcaattt tttgtgcgta gcagattttt gcaatcaaat caaaaaaaga
     5581 ataaaatata actatcaaaa aagacactct actatttaaa agattacaaa ggagttttca
     5641 atgagagaat atgatatcat tgctatcggt ggaggtagcg gaggaatcgc taccatgaat
     5701 cgtgctggtg aacatggagc caaagcagcc gttattgagg aaaagaaatt aggtggaacc
     5761 tgtgtcaacg tcggttgtgt tcctaaaaaa atcatgtggt acggggcgca aatcgctgag
     5821 actttccatc aatttggaga agactacggc tttaagacta ctgatcttaa ctttaacttt
     5881 gcaaccctac gtcgcaatcg tgaagcctac attgatcgcg ctcgttcttc ttatgatggt
     5941 agttttaaac gcaacggtgt agacttgatt gaaggtcatg ctgaatttgt agattctcat
     6001 actgtaagcg taaatggtga actgattcgt gctaaacata tcgtgattgc tacaggtgcc
     6061 catccaagta ttcctaatat tcctggtgct gagctaggtg gctcttctga tgatgtattt
     6121 gcctgggaag aacttccaga gtcaattgcc attctaggcg ctggttatat cgccgttgaa
     6181 ttagctggcg tactccacac ttttggtgtc aagacagatc tctttgttcg ccgcgatcgt
     6241 cctttacgtg gttttgattc ctacatcgtt gaaggtttgg tcaaggaaat ggaaagaaca
     6301 aacttaccac ttcacactca caaagtccct gtcaagttag aaaaaactac tgacggcatt
     6361 accattcatt tcgaagatgg tactagtcac acagctagcc aagttatctg ggctacaggt
     6421 cgccgtccaa acgttaaggg cttgcaactt gaaaaagctg gagtgactct gaacgaacgt
     6481 ggctttatcc aagtggatga ataccaaaat actgttgttg agggaatcta tgctctaggt
     6541 gatgtaacgg gcgagaaaga actgactcca gttgcaatca aggccggacg taccctatct
     6601 gaacgtctct ttaacggaaa aactactgca aaaatggatt actcaactat tccaactgtt
     6661 gtcttttcac accctgctat cggaactgtt ggtttgacag aagagcaagc tattaaagaa
     6721 tacggtcaag accaaatcaa ggtttataaa tcaagctttg catctatgta ctctgcttgc
     6781 actcgcaacc gtcaagaatc ccgtttcaaa ctcataacag ctggttcaga agaaaaagtt
     6841 gtcggacttc atggaattgg ctacggcgtt gatgaaatga ttcagggatt tgccgttgct
     6901 atcaaaatgg gagcaaccaa ggctgacttt gatgcaactg tggcaattca cccaactgca
     6961 tctgaagaat ttgtaaccat gcgttaatcg aaacaaaaga agctgatata aatatgtctg
     7021 cttctttttt aatgattttc gaatcaacaa aaaaattatc caacttgact agtcacgaaa
     7081 atcggctgtt acagtttttg ttaccttgtt tttaaaaaat ggttgacatc gactcctata
     7141 tgagtataat agttactata cattagaaaa gaggttaact attttgaaaa aagctcacgt
     7201 ttatgctatc cctgctattg gggctgctct cattgctgct ttggcacaaa tcagtcttcc
     7261 aattggacct gttcccttca ctctgcaaaa ctttgcaatc ggcttgattg ctactgtctt
     7321 tagaccgaga gaggctgtac tttctgctgg actctatctt cttctaggtg ctatcggtct
     7381 tcctgtcttt gcaggaggtg gagctggttt tcaggcttta gttggcccta ctgcaggcta
     7441 tctttggttt tatctcgttt actctggact tacttcctct ctaaccaaca gcaagagtgg
     7501 tgttgttaag atttttcttg caaacctctt gggtgatgcc cttgtctttg tcggcgggat
     7561 tctcagcttg catttcctag ctggaatggc atttgaaaaa gctcttgctg tgggggttct
     7621 tccctttatc attccagacc ttggcaaact tctggctatt agttttatta gccgtcccct
     7681 acttcaacgc cttaaaaatc aggcttactt tactaactaa aaaaggatat cgagttatca
     7741 tgactcaata tccttttctt ttattttgaa aacttatact caatgaaaat caaagagcaa
     7801 actaggaagc tagccgcagg ctgctcaaaa cactgttttg aggttgtgga tgaaactgac
     7861 gaagtcagta accatacata cggcaaggca aagctgacgc ggtttgaaga gattttcgaa
     7921 gagtattagt tgcctttaaa ggcatccacc atcgtttgaa attcttcatt tgagagagta
     7981 atccctttgc ccattttagt atggtctgga ctccaagcac gaatatcaaa ctttgcaggg
     8041 gcaccattaa agctcacacg gttaatttcc ttggtccaac ctttttcgtt ttcagaaaga
     8101 gtcaacaagt gctcttcgat ttcaaatgta aattctgcca ttttcttctc cttttttagt
     8161 ttcattagtt tattcgtaaa atcttgtaga ttttaggaaa attttatata atattgatat
     8221 aaaagaaggg aggccaatat gagacataaa ttccagcaag ttctaaataa aatacatgat
     8281 tttttaaatg gatatgacca acctgaccag actgaaacca actcccttac agccactatt
     8341 gaagaggcta tccagaaaca aaccgctgtt caccttatct tatctgagac aagctttaca
     8401 ggtgacatca tcaaatatga tcagcaaggc cagcaaatta tcgtgaaaaa tttttccaaa
     8461 aatgtgagcc ggattatccg tataagcgat attcaacgcc tgcgatttgt cccctcaact
     8521 gtccaaacag cccaaaaaaa tagatttaag aaagagtgag atgtagttgc ttcatcccac
     8581 tctttttctt agcgaatttg ttcaaaatgt aaatgaactg cgatatgatc tccataacca
     8641 cttctttcca agtcacgttg taaacgatag gaaatatagt gttctgcaat ggtaatgtaa
     8701 cctgcgccca ataaacgatg ttcaaccata gattgaatca tactgatagt cgcacgttcc
     8761 accttggctt cttgtaaatc caaaactacc ttcttagtga cttgagcaag attttgacgc
     8821 aaatcatctg tcaaaacata aacagtttgg gctgccttca agatggcttg gtaaatctta
     8881 tctggattaa attcagcaat ttcgccatta cgtttgatta cttgcatagg tttctccttt
     8941 attctttgtt ttctttgatt tctgccagca ttttttcttc ttctactgtc agttgataat
     9001 gttcaagtaa atccggtctg cgctcgtagg ttttctttaa actctcgtac aatcgccact
     9061 gacgaatctt ttcatgatgg ccactcatca atacatctgg cacgaccatg cctcgataat
     9121 catagggacg tgtgtactga ggatattcta aaagacctga agaaaaacta tcatcttggt
     9181 ggctagactc cttgccaatc acttctggaa tcaggcgaac tgtagcatca atcatggtca
     9241 tagctgccaa ttctccacca gtgaggacat agtcacctag ggaaatctca tctgttacca
     9301 aggtcttaat gcgctcatca taaccctcat agtgcccaca gataaagatt agctcttcct
     9361 cttgagccaa atcttcagca taagcctgat caaactgctt tccagcagga tcaaggagaa
     9421 taacgcgcgg atttttcttt tcaatagcat caaaggaatc gaaaataggt tgtgctctga
     9481 gcaacatgcc ctgaccgcct ccgtagggct catcatctac atgacgggcc ttttcagcat
     9541 tttctcgaaa attatgatac tggatatcca agagcccttt ttctcgagcc tttccaacga
     9601 ttgagtgctc cagtggagaa aacatctctg gaaagagggt taaaatatca atcttcatcg
     9661 tctaaccctt ctaagatttc cacatcgacc cgtttatttg gaatatcaac attgagaacc
     9721 actggtggga tataaggtaa aagcaaatca cgtttgcctt ttcgtttgac cacccagaca
     9781 tcattagcac ctggttgcag gatttccttg atggttccaa ccaagctatc accctcatag
     9841 acttccaaac cgataatctc gtgatagtaa aattcaccat cgtctaggtc attcaaatct
     9901 tcctcagcga ccttgagact gtatcccttg tacttttcga tagtattgat atggtacata
     9961 tctttgaatt taataatgtc aaagttcttc tgtttacggt ggctagcgat ggtcactgtt
    10021 tggacaaact gatctttttc atcaaacaaa gccagctcag ctcctttttt aaaccgttct
    10081 tctgcaaaat ccgtcacaga caagactcgc atctcaccct gtaatccctg cgtattaacg
    10141 attttcccaa cattaaagta gttcatcttg tctcctgtaa tctccttttt tccatcttat
    10201 tctgacaatt ctcgaataat agccgcaatt ttttccgatt ctgaccattg taaataatgg
    10261 tgattccctc ctaaaatgag tttagtattg gaagtccaat attctgattc tctgtactct
    10321 ttttctctat aagtctgaca aaaaataaat acagggacat gagattctat cgacaaattc
    10381 tcaaaatttt cctcagtaat ctctccagat atctgaaatt ctggatcttg attttccaac
    10441 tctaagcctt tttcttgcat taattcccag atttttttat tcgtttcagg actaaatgtt
    10501 gcttgagtta agttcttaaa ataaagttca ggaccacact cgtcaatcag cctcatctgc
    10561 tcttccattt ctggataagg attttctgaa aaatcagcaa acatgacttt tttagttgtc
    10621 ggttcaattg ctactaaagt ctgacgctta attggtttct cgagtaattt gcaagctaaa
    10681 attccactcc aactatgtgc acaaagtata tattcagaaa tccctaattc ttcaagtact
    10741 tcataaaccg catctgcaag attatctaga ttttttccag cttggtcatg aatcggactc
    10801 ctacctgtgt tcggaaaatc aattgtcaaa taaccaattg taggaggagg tttttcaagt
    10861 ataagtgaaa aattttcata acttggtagc aaacctgctc cgtttagaca aactagcact
    10921 ttcttttgct tttgataagt aacagagagg ctaccaattt ctgtagatac ttcaaacctc
    10981 ttcataaaga aatccactga ttctatataa tgaattatta aaaatcctta tcctttattt
    11041 tatcacgttc caaggatttt ctcaagttgg aggaagggga caatatctct actttccctt
    11101 caagaatcct tccaaattat gtttatgttg gtaattaacg gctgcggttt tgtctttctc
    11161 aaagacagtc ttggtaaggt caatatgatt aatagctacg attgcgacgg tgtagtaaat
    11221 gatatcagcc agttctctgg caagttcctc gttcgaatcc tatcccttct tttcgaccag
    11281 agcgcctatt caaaacctcg gctacttctc cgacttcctc cactaacttc ataaagagac
    11341 cttcatcagt ccgagactgc tgttaatgtt cgattaagta gtcttggaat tgcctaaacg
    11401 ttcaatcttt tatagtatat tgaaactaga atagtacacc tttacttcta aaacattgtt
    11461 agaaatcgat ttgactgtcc tgatcgattt gtcctgttct tgtttcattt tactatatct
    11521 tctattccac acaaaaaagc gagacatccg tcccgccctt cttatttttc gtcaataacg
    11581 attcttactt ttttgtattc agttgggaca gagtagacaa tcgttcttat cgcagaaata
    11641 gtgcgaccct tacgaccgat tacacgaccc acatcgcttt gatcaagatt caaatgatat
    11701 tccaaaaatt ctggtgtatc ctcaatcttg atagttaagg catctggttg tgaaattaag
    11761 ggtttcacaa tcgcaataat gagattttca atcgtatcca tctgtcaacc tactttaaac
    11821 ttattttgaa aatttagaat cgtggaattt tttcaatacg ccttcttttg aaaggatgtt
    11881 acgtactgtg tctgaaggtt gagctccatt agccaaccat gcaagaacgc ggtcttcttt
    11941 caaagttact tggttttcag caacaagtgg gttgtaagtt ccaactgttt cgatgaaacg
    12001 tccgtcacgt ggtgaacgtg aatctgctac gttgatacgg tagaaaggtt ttttcttaga
    12061 acccatacga gtcaaacgga ttttaactgc catttttaaa gtctcatttc tttaattttt
    12121 tatttcggtg aaatagctga gctatttagc acatgttcta ttatagcaga tttctggcag
    12181 gtgtcaagaa aaaaacttga cagactataa atttcttaaa gtatttagaa atttgttaga
    12241 ataggaaata aatgtttgaa agatgctatc cgtgaatact attttagaaa aattttataa
    12301 agaacaccaa gtcaaaccct tcatatcgcc tgaacgagag ttggagagtt ggatacttgg
    12361 cttctaagtt ccaaacccgt tcccaagcga aatatggact tattagcaga tgattcacta
    12421 gcaagagata tcattttact atggagaatc cagtttggta cttttaccac tgaaacatga
    12481 ttttaaaaac tcccattcga atatgattca aaattcgctt agaatcaatg ttttcccact
    12541 ttttcaaaaa ataaattttc atctaattta aataactttc aattaagtgt gaattttgct
    12601 taaaatcata aaaaaacacc ccatggtgtg aaccatgaag tgttgtaaat gctgtattgt
    12661 agctagttct taacgtttag agaactggct agctttacga gctttcttaa gatctggttc
    12721 cctaaatact ttgagtacac ttatggcatt gatgccccaa aacatctaaa aactctggta
    12781 gaaaaagggt atgctcttgt cgaaacttct tttgactcac ttgaccatct aaatactacc
    12841 atgaaaaaga atatcctgaa gaagaaggga gttactggac tttctaaaat gaaatcttgc
    12901 aacctggatc aagctcttca tgagcatttt tcagaagaag aattagctgg tcactttcat
    12961 gtccttctat ggactttttt acaatggcat tgctatcaca cccaatacct atctaagcgc
    13021 ctggttcgta aactttattg cagctcttcc tctaaatttc ctaattgttg aaccaattgc
    13081 ccgttttata ctaagttctt ttcagaaacc atttactggg gaagaagttg aagaagttga
    13141 agattttcaa gatgatgatg aaatcccaac tattatctaa gccagttctg taaactacta
    13201 atatttgaaa tccacttcct tttagggtac aatggttata aatgaatttt tgagaggatc
    13261 agaatgaaaa aactagcaac ccttctttta ctgtctactg tagccctagc tgggtgtagc
    13321 agcgtccaac gcagtctgcg tggtgatgat tatgttgatt ccagtcttgc tgctgaagaa
    13381 agttccaaag tagctgccca atctgccaag gagttaaacg atgcattaac aaacgaaaac
    13441 gccaatttcc cacaactatc taaggaagtt gctgaagatg aagccgaagt gattctccac
    13501 acaagccaag gtgatattcg cattaaactc ttccctaaac tcgctcctct agcggttgaa
    13561 aatttcctca ctcatgccaa agaaggctac tataacggta ttaccttcca ccgtgtcatc
    13621 gatggcttta tggtccaaac tggagatcca aaaggggacg gtacaggtgg tcagtccatc
    13681 tggcatgaca aggataagac taaagacaaa ggaactggtt tcaagaacga gattactcct
    13741 tatttgtata acatccgcgg tgctcttgct atggctaata ctggtcaacc aaacaccaat
    13801 ggcagccagt tcttcatcaa ccaaaactct acagatacct cttctaaact ccctacaagc
    13861 aagtatccac agaaaattat cgaagcctac aaagaaggtg gaaaccctag tctagatggc
    13921 aaacacccag tctttggtca agtgattggc ggtatggatg ttgtggataa gattgctaaa
    13981 gccgaaaaag atgaaaaaga caagccaact actgctatca caatcgacag catcgaagtg
    14041 gtgaaagact acgattttaa atcttaaaaa ccaaaaaaaa tacagtatcc acattcggta
    14101 ctgtatttct tttactctca ttcttaagtt aaattattaa aatcccatat ttggtctatc
    14161 cagccttcat aaaagtctgg ctcgtggcag accataagga tagatcccct atattctttg
    14221 agagcgcgtt tgagctcatc ctttgcatcc acatccaaat ggttggtcgg ctcgtccagc
    14281 actaaaacgt tgttttcacg attcatcaag agacagaaac gaaccttggc ttgctctccc
    14341 cctgataata cttgaatctg gctttcaata tgtttggttg tcaaaccaca acgggcaagg
    14401 gctgcacgga cttctgcttg attaagggca ggaaaggcat tccagacagc ttcaagagga
    14461 gtttggcgat taccgccttc tacttcctgc tcaaaataac caagttctaa ataatctcca
    14521 cgctccactt ccccagcgat tggcgagata atgcccaaga gactcttcaa gagagttgtt
    14581 tttccaatac cattagcacc aataatcgca accttttgat tgcgttcgaa ggtaagattt
    14641 aaaggcttag taagaggacg gttgtaacca atttgcaagt tcttggcttg gaagataaag
    14701 cgccctggtg tacgagctgg tttgaaatca aaggatggtt ttggtttctc actttggagt
    14761 tcgataatat ccatcttatc caatttcttt tgacgagaca tagccatatt acgagttgca
    14821 acacgggctt tattacgagc cacaaagtcc ttgaggtctg caatctcttt ctgctggcgt
    14881 tcgtaggctg cctctagctg agatttcttc atagcataaa cttcttggaa ctggtagtag
    14941 tcaccagagt aacgcgtcag ctgttgattt tccacatgat agacaatatt aataacgtca
    15001 ttgaggaatg gaatatcgtg cgaaatgaga acaaaggcat tctcatagtt ttggagatag
    15061 cgcttgagcc aatcaatatg ctcagcatcc aagtagttgg tcggctcgtc caacagcaaa
    15121 atatcaggct tttcaaggag aagttttgcc aaaagcacct tggttctttg cccacctgac
    15181 aaagaagtta catccgtatc catgccaaag tccataatac caagagcacg cgctacttcg
    15241 tcaatcttag catccaaggt atagaaatca cgactctcca gacggtcttg aagttctccc
    15301 acttcttcca tgagagcatc aacatccgca ccgtcttcag ccatttccat atagaggtca
    15361 ttgatacgag cttcagcttt gaaaagctca tcaaaagccg tacggagaac atcacgcacc
    15421 gactgtcttt cagtaaggac agagtgctga tccaagtaac cagccgtcac atatttggac
    15481 cactcaacct ttccttcatc tggcagcatt ttaccagtca cgatactcat aaaggttgat
    15541 tttccttcac cattggcacc gaccaggccg atatgttctc ccttgaggag acggaaggac
    15601 acatcttcaa aaattgcacg gtcaccaaaa ccgtgactca gatttttaac ttctaaaata
    15661 ctcattttaa ttccttacct tgtttttatg taatcgttta taaaggagcc aagccagata
    15721 gccacccaaa gtgttggtcc acaaatcatc aatctcaaag acgcgattga aatcaaagaa
    15781 aaagtccaag attaattgcg tacactcgat tccaagactc acaagaaaac taaaaagaag
    15841 gacctttttt gttttccgca aatttggaaa tagataaagg agttggaaaa tcagaggaaa
    15901 aaacaagaag acattgagga tattttgtaa aaaaatccaa cataattgtc caatgtcact
    15961 cacttcgccc agtttccaga gagaattgaa aggagtcaaa agaaaaacca ggcgtccaag
    16021 atgctgaata cctggagttc ccactcccac ggtagattgt tcttgaggag taaagcaaaa
    16081 acagacaatg caaatgctat agaaaatgac tccccagacc aaaatatgat tataagtctt
    16141 cttcatcatt aaggatttac cgctgcgact gccttctggc ggtcacgttt cattgtgtta
    16201 gagcgcaatt gtccacaagc tgcgtcaata tctgtaccat gctcttgacg aaccacacag
    16261 ttgacccctt ttttcttaag cgtatcatag aaagccaaca cgcgctcttt gggactacgg
    16321 ctatattggt catgctcact aactggggta taaggaatca agtttacata agacaatttc
    16381 ttgatgttct tgagcaattc agccaattcc aaggcttgtt ctacaccgtc gttgacttca
    16441 ttaagcatga tatattcaaa ggttacacga cggtttgttg tctcaatgta gtattcaata
    16501 gcagcaaaga gtttttcaat cggaaaggca cggttaattt tcatgatact tgaacgaagt
    16561 tcattgttgg gtgcgtgaag agacacggca agattgacct gaaccccttc atcagcaaag
    16621 tcacgaattt tatgagccaa acctgaggtt gaaaccgtga tgtgacgagc accgatagcc
    16681 attcctttat catcattgat agtacgaaag aaattcaaga cattgttgta attatcaaag
    16741 ggctcaccga ttcccatgac aacgatatgg ttgacgcgtt catcctgacc acgctcatca
    16801 aagtatttct gaaccagcat gatttgcgct acgatttcac cgttattgag gtcacgctgc
    16861 ttcttaatca aaccagaggc acagaaggta caaccgatat tacagccgac ctgagtggtc
    16921 acacagacag ataaaccata gtgttgacac atgagtacag tctcaattaa cataccgtca
    16981 ggcaattcaa agagatattt gactgtacca tcagcagact cttgcacaat acgttgtttc
    17041 aagggattga ccacaaactg gtcattgagc ttagcaatca aatccttgga aaggttggtc
    17101 atttcttcaa atgactgcac acgtttacgg tagagccatt cccagatttg atctgcacgg
    17161 aatttctttt ctccctgctc caatacccat tcctgcatgg tttgatgtgc caaactatga
    17221 attgagggtt tcatttcttc tccttattct ctactcactt ctgacgaatg acaaaatgac
    17281 gttgttcctt gtcctctttc tgagaatgct ggtctttctg acgacgtcta tttttcttat
    17341 ctgcattcga ctttcgttta gtttgagtcg gtttctttcc ttttctagaa ggtgtttctt
    17401 cttccgtctt acgcattttc ttgtcaaatg atgctcgctt aggggcttca ttttctaaga
    17461 caaaataggc acaaccataa ctacaatact ctaaaaggta gtcttgtaaa cgactgattt
    17521 tttcaagttt ttcttctgtt cggtcatcct tgtaaaaacc tcgtaggcga agctgttcgt
    17581 tgctccagtc ccccacgata taatcaaact tggttaatac ttctgaaaaa cgctgattaa
    17641 aagtcgtcac atcaaaggca tccttgatat tttcaaccaa ggaaaaagct atcccttccg
    17701 tttcgacctt gtccccgtgt aaatggaact ccggaccagg aaacttgtta tagttgtata
    17761 attcaggtgc aatttctttt cgcatagata tcctttttcc acgattactt aatactttat
    17821 tctaccataa tttctagcag ttagcacgtt tctcataaaa atgaaaaaag tctgacgatt
    17881 ttgtcagacc agaatcttat aacctaaaaa agagaagaac aattcttccc tccaactatc
    17941 attatttagc agctgcgtac aattcatcta ctttattcca gttgattact gaaaagaaag
    18001 ctttgatgta gtcaggacgc acgttgcggt atttcacgta gtaagcatgt tcccaaacgt
    18061 ccaagcccaa gattggtttt ttaccttctg agattggtgt gtcttggttt gctgttgaag
    18121 tcacttcaag tttcccttct ttgttgacaa ccaaccatgc ccaacctgaa ccaaaacgag
    18181 ttgttgctgc tgcagtgaag gctgcttgga attcttcaaa tgaaccaaat gttgcatcga
    18241 ttgctgctgc cagttctgct gaaggagctg ttttctcggg agtcatcaat tcccagaaaa
    18301 gagcgtggtt caagtgtccg ccaccattgt tgataagtgc ttgacggata tcagctggga
    18361 tagattctac atcagcaagc aaggcttcaa ggtcttcacc gatttcaggg tgtttttcta
    18421 aagctgcatt ggcattgttg acataagttt gatggtgttt gtcatggtgc aaatgcattg
    18481 tttccgcatc gatgtatggt tccaaagcgt cgtatgcata tggaagttct ggtaagataa
    18541 tagccatctg taatacctct ttttctttct atatgaaaat gataacgcaa acattcactt
    18601 ttttcaagtt ttttgcttat agataaggaa atcactgaca tactttctaa taaaataagc
    18661 aaatcagcaa gaaacccacg acaagataat cctgacgcgg gttgtagttt caacaaatgt
    18721 caattgacct gactagcaat ctgtaagagt gccttttcaa aaaggaaacc tttttcataa
    18781 agacctgtct taatctgata gtctgtctca atcaaatagg aaatagcttg cttcagaaag
    18841 ctcaaagaaa gtcctctcga atctcttaat gcaaacttga tttgataagg atttgggtta
    18901 cgtcccagat aactacctaa actacttgca atctgcgatt ctgtttggcc agactccgcc
    18961 aaaatcttca cctgagtaaa agtccgaaat tgtcccagca tgactgcaat cagtttgatt
    19021 tcatcttccc cttgcaaggt caagtctctc accaaatcgc gcgcctgatc catcttttta
    19081 gtcagaataa actgagttaa atcaaaaata ttgtcctgca aggtcttggg aattgcgtta
    19141 acaatatcct cttcctcaat aacagaattc gccttatagg actgtaaaaa gagaagattt
    19201 ttctggattt cgctaaattg aaaccccgac ttgatgagga gattttcaaa agaatgattg
    19261 gtaaactgca gaccttgttt ctgactccac ttttggaaat actggcgcaa ttcttgttct
    19321 tttacttcta ctgcatcgaa gaccttggca tcacgcttaa gtaatttgac taaccgtctt
    19381 ttgctatcca gctttccttc tgcaaagatt atcaacttgg ttgttggaga aggattgtca
    19441 aggtattcct caaatgactt aagctcatca tctgtcaaaa agcgtttctt agcagtcgtg
    19501 atatccataa aataatctaa tatcacgatt ttctcatccg caaagaaagg aaggctgacc
    19561 aactccagtt ccacatcctt gtaaactact tctttcatat caaagtaggc aaagttgagg
    19621 tcagcagaat catacccaat ctgtttcaac atttgactct tcatcacttc aaactgaccc
    19681 tgatctgtcc ctgtaaatag gctcaggctc ggtaaatttg ataaagtcaa cttctgactt
    19741 tcttcaatgg ctagcatcgt ctctcctttc ttcagatttt ttgatttaat ttagtcaata
    19801 tagcgcaatt tcccacggaa atcttctaag ctctcgtagc ctttttccac catgattgct
    19861 ttcagttcat tggtaatgcg gtcaaaagca ctgacgcctt ctttgtgaag ggtcgttccc
    19921 acctgcacca tacttgctcc acagaggatg tgttcaaagg catctcgacc agtcagaacg
    19981 ccacctgttc cgataatttg gatttgagga tttaaacgtt gataaaaggc gtgaacattg
    20041 gctagagcag tcggtttaat gtattctcca ccaattccac caaaaccatt cttaggccga
    20101 ataacgacag attcgtcttc tatatagagg ccgtttccga tagagttaac gcagttgaca
    20161 aacttgagcg gatatttgtt gaaaatagct gccgcttgat caaagtgaac aatatcaaaa
    20221 taaggtggca atttaattcc aagaggtttg gtgaagtaag caaacacttc tgccaaaatc
    20281 cggtctgttg tctcaaaatc ataggcaatc tgaggtttac ctggaacatt tggacaggaa
    20341 agatttagct cagtcagacc acgaaaatca ctctcttgga cttttttcaa aatagtatgg
    20401 gtttcctctg gagacatgcc gaccagagat aagaagaaag ttcggttcga ctctttttcc
    20461 tgcaaatcta aaagataatc caaataatag tctaagccat tatttggcaa gcccatagag
    20521 ttgatggaac caagtggaac atcttggtag cgtggctcag gattcccctg acggaagtcc
    20581 aaggtcgctg tcttagtaac aaaggttcct gccgctgagt ttttgacctc ttctaactcc
    20641 tctatcgtca tacaagccac acctgctgca ttcatcaagc aattgtcaaa ctcaaaacca
    20701 gcaatttgtg ttttcgttga taccatgatt ctaatcctcc agatttcttt tattgctaat
    20761 attataccat aattttaatt ctaggtttac tagattctgt ggttctatct atttatttgg
    20821 aaaagaaagt ctagtacaga agtcatgcta tagaaacagc tagtgtattg gaagtttgaa
    20881 caaggcttgg gtaacagact tttgaatgaa gtccaagcaa caaggagaaa tctcaaccat
    20941 gagtccattc catgactctg ttgctctaga aaaccttgca atagtcaagt gataacgaat
    21001 aaaactttgg attgaaatat ccccatgatt atctattacg aggagaaatc tcaaccttta
    21061 tcatttttaa agaaatatag taaaatgaaa caagaacagg agaaatcgat caggacagtc
    21121 aaatcgattt ctaacaatgt tttagaagtt gaagtgtact attctagttt caatctacta
    21181 tacatgtaaa tctctacttt cgcaaaatgg attttcagaa cagtatccca gtatagttaa
    21241 aaactataaa aaagagagga cgttcccctc ttaaaatctt attttactgc ttctttcaaa
    21301 gcatctacct tatccaaacg ttcccatgga agatcaatat ctgtacgtcc catgtgaccg
    21361 taagccgatg tttgacggta aattggacgc ttgaggtcca gcatttggat aatccctgca
    21421 gggcgaaggt caaagatttg acgagccgct ttttcaagtt gactttcagc tactgttcct
    21481 gtaccgaaag tatcgatacg aacagaaaca ggttgcgcaa caccgatagc ataggccaac
    21541 tgcacttctg ccttcttagc aaggcctgct gcaacgatat tcttggcaat atagcgagcc
    21601 gcataagagg ctgaacgatc caccttagtc gcatctttac cagagaaggc accaccacca
    21661 tgacgagagt agccaccata agtatctaca ataatcttac gaccagtcaa acctgagtcc
    21721 ccttgaggac caccgattac aaaacgacct gtcggattga taaagaattt tgtcttatca
    21781 tcaagataag aagatggaat aacttctttg atgaccttgt taatcacatc ttgatggatt
    21841 tgttcattag tggcctctgg atcatgctga gtagaaataa cgactgtatc tacacgtacc
    21901 ggacggtcat tttcatcgta ctcaactgta acttgtgatt ttgcatctgg acggagatag
    21961 ctaatttctc cagacttacg aagttctgcc agacgacgaa ccaatttatg actgagtgca
    22021 attggcaatg gcatgagctc ttctgtttca tctactgcaa atccaaacat gagcccttgg
    22081 tcacctgctc caatcaagtc cagtggatct tgatcagcat ttccacgaac ctccaaggct
    22141 tcgttaacac cttgagcgat gtcaggagat tgttccacca aagatgggtg tactcccacc
    22201 gtctcagcag aaaatccata ttctgtattg gtataaccaa tctctgcaat ggtatcacga
    22261 accacacggt taatatccac ataggcattt gtagaaattt caccaaaaac gtggacagaa
    22321 ccagtatata cagctgtttc agcagcaacg tgcgcctctg gatcctttgc taaaatagca
    22381 tccaaaatcg catctgaaat ttggtctgca atcttatccg gatgcccctc agatacagat
    22441 tcagacgtga ataatttacg ttctgacata aaaatgtccc cccttaaaaa atattgttat
    22501 agagttacaa agtactgata ggaatttcca ttatctaaga gttactagct tcagaaataa
    22561 aaacgatact tttttatttc tgaagctagt aaggcacata gggtgaccgc agtatggcgg
    22621 caaccgtaga aagacgagcg acctcgaagc cgtcattctt tgcgaattgc aaactactga
    22681 taggaaaact cttcgtaata aatacctacc atcttatcgg gactatataa ctttatcatt
    22741 ataccatttt taatcgcaat ttgcagtctt taatgtagtg tttcggttta gatagttcgt
    22801 tctcataaat aaaaaagttg gagctcagta ctccaacaat ttctattaaa atgtttgacg
    22861 tttagcttta cgctctgcac gaccgcgagc gcgattttca gcacgcttgg ttttacggcg
    22921 cttttcatca accgcccatt gaattttctt cttataaccc ggtttgactt ttttcttttt
    22981 ctttttaacc aaaccaatca tttcgatatc aagtttatct tgttttttct cacggttggc
    23041 acgacgatca cggtcatagg tatcttgaaa ttccccgtct ttgaccatct taggactaaa
    23101 cttgattccc aatttctcca actcacggat atccgagtca tcacttggct gataaagggt
    23161 aatagctgta cctggtaggc catttcgtcc agtacgacca acacggtgaa caaaaaaaga
    23221 taagtcttgc ggaatggcat cattgatgac atggctgaca ccttcaatgt caatcccacg
    23281 tgctgccaaa tctgttgcga caatatactc aaaatccaga ttttgcacct gattcatgat
    23341 tcgcttgcgt tcacgagggg caatatcgcc atggattttt gcaaccttca agccttgagc
    23401 agtcagatat gaatgcaatt catcagcacg cgttttagtg ttaacaaaaa tcattgccaa
    23461 atacggctgc atcaactgag tcaactggta aatttgagca ttcttatcat gtcccttggt
    23521 cgaaatcaac caattatcaa tggtgtcaga aataaccgtt ttggtcttaa ttttctccat
    23581 aacaggattg gataagtatt ttttcaagaa tggttgcagt ttttgtggga tagtcgctga
    23641 gaagaccatg aattgcaagt cttttggaag actgccagca atcttatcaa cagtttccaa
    23701 gaatcccata tccaaggtca tatccgcttc atcaacaaca aatgtcttgg ctttatgaat
    23761 agccaaatca ccagatttaa ccaagtcgta gatacggcct ggtgttccaa taacaatatg
    23821 aggctgattg cttgccaatt tctcaatctg gcgagcctta tccgtaccac ccacataatt
    23881 aaccacacga acttcgacat ctgagtgagc tgaaatctga cgcgctactt ggtaaatttg
    23941 agtagccaac tcacgactcg gtgcagtaat cactgcttgt acactatcgc tagcttcatc
    24001 taattgctgg aaaatcggta acaagaaagt atgagtctta cctgaacctg tttttgattc
    24061 tcctactagg tcacgacctg ccaaaacaat aggaatcaac ttatcttgca cctctgttgg
    24121 agttgtaaat tttaactcct tcaaggcttc tctaatatag tttttaaatt gaaatttcgt
    24181 aaatgacata acatcctcga ttctatctat cttatcaatt ataccatatt ttattccatt
    24241 acagtagtct cacttattta ggctatttcc agtagcttct ctagtaagaa aaggctagaa
    24301 ttttatagtt ccaacctctt ttcagttatt atttccagtt taatatagca ttcaagccat
    24361 agtgatcact cacttgtgga ctcttgttac catcaaatac gacatgtaaa ttttccaccg
    24421 ctaactcttt ggtagtaaag acataatcga ttcgaagggg ttcagtgttc cctttccagc
    24481 catcaatttc aggcggaaca gtatagctac cacttttctc ttgagcaact tcaaatgcgt
    24541 cttgtaagcc taatggacta gctaaaatag cttggtaacc ttcctgacct gctgggttgt
    24601 taaaatctcc agctagtaaa agtggcttgt tcaatttttt caagacagcc tcaaatcgtg
    24661 cccattcttc ttggaaacct ttatcccacc aagagagatg aacactggca actgctagct
    24721 ccttgccatc gactacagtt tcagctagga caacacggcg agtatgatag tctgttggat
    24781 catccacatc tgaaaccaaa atttctctgg cttcaatagg tgttttagac aagatagcca
    24841 caccttcatg gtagcggtca tagccgatat ggttataagc ccaggtccag tagtaatttt
    24901 tcccttgctc taacaacttt tcaaccaaga gtctaacata atggtcttgg tgaataggct
    24961 cagctgctgg caaagcttga taaaggtcat taacctccac ctctgacgag gtcatctcct
    25021 gattgatttc ttggaaacaa atcaaatcat agtccttttc aagaatatct tcaagcaaaa
    25081 tctggaattt ttcctttgct tctttctcca tccaactgtg agtattgagt gttaaaaatt
    25141 tcattctttt ctcccaaaat aagaggttgg aatacagctt ccaacctcaa gtatattaca
    25201 attctacttt agcaactgct gttttagctg caagagaacc tgttttttct aatttaactg
    25261 atttaattgc atcaccattt gtgaagacaa ctactgttga agtttcacgt cctgctgcac
    25321 ggatagcatc caagtcagct gtgacaagga gatctcctgc tgcaactttt tgtccttcag
    25381 caacatgaac tgtaaatggt ttaccttcaa gacttactgt gtccaaacca atgtgaacca
    25441 atacttcaag acctgcttcc gtcacaatac caaaagcatg ttttgttggg aagatgcttg
    25501 atacagtacc tgaaactgga gatacaatgt ttccatttgc gggttctact gcaaatccat
    25561 cacccatcat tttttgagca aatactggat cctttacttg ttccaaacca acaacttgac
    25621 cgtctgctac tgaataaact tcctcagtaa gatctttgaa gtgaacagtg ttttgttgtg
    25681 cttcagtcat ttggcttgga agagtttcag gaatgatttc acctgaatca aggatatctt
    25741 ggatatcaga tttcaatatg tcagcttttg gaccgtagat agcttgaacc ccttgccctt
    25801 tcatgacaag acccatagct ccttctgctt tccattgctc tgcatttcct actttatctg
    25861 catctttaac agttacacga agacgagtca tacatgcgtc aacatcaacg atgtttacac
    25921 gtccaccaag aaggttgata atgtttacag cttgagagcc tgctgcaact ttcacttcgc
    25981 tgctggtttc ttctgaacct tcagcagttt cgtagtttcc gttgcgccct ggagttgcgt
    26041 agttgaattt ttgaatcatg aagtttgcga taaagtacat gattacagca aagagaacag
    26101 ttacccaaac gaagttaacg atatccatac caataccagc actgattgca ataggtgtac
    26161 gagtcaagaa ctcgattgaa ccgaatgagt gcatacgtag gtttacgacg tcagccatag
    26221 cgaaggcagc accttgaaca agtgagtaaa caagatacat aggtgttgcg atgaacatga
    26281 acatgtattc gattggttca gtaacccctg tcaagaatgt tgcaagagct gttgcaatca
    26341 tcataccttt gtatttatgt ttcttgtcag catcaacatt acggtagata gcaacaatca
    26401 cacccatcaa gataccgaat gaaccgatca tttgtccaac tttgaaacga gctggatgta
    26461 ctgtatctaa caagtgttgg tattgactag catcagtacc tttaaggttt acaaggtctg
    26521 ttacccatgc aagccatagt gggtcttgac cgaatacttg agtaccttta gctgcaccag
    26581 ttaaaatgtc ataagtacca ccaagagctg tgtagttcat tgggatagtc aacatgtggt
    26641 gaagaccaaa tggcaagagc aaacgttcca aagtaccata caagaatggt gcaagaattg
    26701 gagcagtttc ttgtgagttg gcaatccaga taccgaagtt attgatacct gtttgaacta
    26761 ctggccagaa agcagcaagt agaattgcag cgattgctga acgaagaata actacaaatg
    26821 gtacgaaacg tttcccgttg aagaatgaaa gtgcatcagg aagtttacgg aagttgtagt
    26881 atttgttgta agcagttgcc cctacaaaac ctgagataat ccctacgaat acccccatgt
    26941 tcaaggctgg agcttcaaga acactgataa agtaatcagc aactttgatt gaaccaccaa
    27001 agaaagtagt taccatagca tctggatttt tcaacatatc gcctgataca ccaaaaattg
    27061 taccagtgat acggttaatc aagatgaagg caagaccagc ggcgaaagca ccaccagcac
    27121 gttctttagc ccagcttcct ccaatggcta gggcaaacaa aatgtgaagg ttaccgataa
    27181 ccccccaacc gatttgctca agaattccac ctgtgatgac aagtggtgta aaggttgggt
    27241 taatcatcac gatagactta ccgattgaaa tcatcaaacc agcagccggc ataaccgcga
    27301 taactaccat caaagcctta ccgaattttt gccaaaattc gaaagacaag acatttttga
    27361 atgtatcttt catcattcaa atctccttta tttttattta ggcaaacgtt ttacgaaaac
    27421 gtttgcacct tctatgattt aattatacca ctttaatttt ttttgtaaag gcttttataa
    27481 aaaaattaca cttttttcta aaaaatttct agtgcgccaa atttcaagtt caaattagcc
    27541 atcaagaagt cttctctggg ggacttcttt ggaagctctt ttcttctacg catctctttt
    27601 caaaaactct tgtagcaaaa aaggagattt tacaatctcc tcataaaagc agctatttta
    27661 cctaaatctt caagaatcgg cgcatggata ttcctgatcc caatgaacca atgaaaaccc
    27721 caatcacaaa tagtagggca atcatcaacg gactaaataa atctggacta atcatggata
    27781 gattttgccc taccaacgat ttgttgacag attggtaaac aatttgataa acaataaaga
    27841 ccaaaacaga tggtgcgata gctcccaata aaccgataaa ggctccttct aacaagaacg
    27901 gtccacggat ataactgttt ttagctccga ccaagcgcat gatttgaatt tcgcgactgc
    27961 gggaaataat ggtaatacga atggtatttg aaatcaagaa aactgcgata aaaattaaca
    28021 aagcagcaat ccctagtccc caaacacgga taaatgaagc taacttgaag agtctttctg
    28081 tattggcacc gccatcttga acctcagaga caccttcaat ttttttagca tcttcggcta
    28141 tagtttttac atcatttgga gtgtttgcct ctacaatata ggcatcatag agaggattgg
    28201 catctccttc aaagattttc cagttatctc ccattatctc ggttaatttt tcatattgtt
    28261 cttctttact tgaaaaggta acacttttaa ccgtagacat gttcttcaaa gaatcatata
    28321 ccttgtggta gtcattattt gtaacagttt gaccttcttt ttcaattgtc tgactattat
    28381 cttccacatc ctttcggata taaactacta cacggacatt attttcaata tctgtagcta
    28441 gtttcgctgt attgaaaata acagatgcaa atattgccac caaggtcaaa gtaatcatga
    28501 ctgaactgac agcagctact gtcatccaac catttcgttt caaacttttt aaggcttcaa
    28561 ataaatggcg aaaaaatcta ctaatcatcg tatccatact ctccttttga ttcgtcacga
    28621 acgacacggc cattttcaat ggcaatgaca cggtggcgca aggtatttac aatctggcta
    28681 ttatgagtcg ccatcaaaat agttgttcct tgtaggttaa tccgttccaa gagattcata
    28741 atttcccatg aattatccgg atccagattt cctgttggct catcagctat caatactttg
    28801 ggattattta caattgcacg cgcaatcgca atccgctgtt gctccccacc tgagagttca
    28861 tttgggaaag aacgaacctt atgcttcaat ccaaccaagt ccaaaacttc catcactcgt
    28921 cttttgatat tacggcgatt ttccccgatt acttccatag cgtaagcaat attttcatag
    28981 acagttttct ttggtaacaa tttataatcc tggaagacaa ccccaacact acgacgtaga
    29041 agcgggacat ctttcttttt gatcttaacc agattaaaac cagcaactga taggcttcct
    29101 ttatcgattt ttacttcacg atacagagaa cgaataaaag ttgacttccc tgctcctgaa
    29161 ggtcctacga tgtaagcaaa ttcccccggt tgaacgctaa ccgaaacacc gcgtagagca
    29221 gtcgttccgt tgtcgtattt tttaacgaca tctctcattt caataattga catgtgagtt
    29281 cctttctatc ttagctaatt cgccacttga gataagcatc gataaaacca tctaggtccc
    29341 catccataac cttatctacc tgagcaacct caaagctagt tcggtgatct tttaccatag
    29401 tataaggcgt gaagacataa gaacggattt ggcttcccca agtgatctcc tttttctcac
    29461 ctttgagaga atctacctcc gcagccttct tatcttgctc catttgatag agcttagcct
    29521 gcaacatctt catggcacga tctctatttc catactgggt acgatccact gttgattgga
    29581 caacaattcc agttggaatg tgggttaaac gtacacctgt tgaaacctta ttgacgtttt
    29641 gtccaccggc accacctgaa cggaaggtat ccatcttgat atcatcttca cggatttcca
    29701 cttcaatagt atcatccaat tctggcatca cttctacaga tatgaaagag gtatggcgac
    29761 gtttggcaga gtcaaatggt gagattcgca ctaagcggtg aacacccatt tctgacttga
    29821 ggagaccata ggcattaggc ccttcaaatg ataaagttac cgacttaata ccagcctcat
    29881 cacctgcttg gtaatccaac acttccactt taaagccttt agcattacca taacgagtat
    29941 acatacgaag caacatatca ccccagtcct gcgcctcagt accaccagaa cctggatgga
    30001 tttccaagat ggcattgttg tggtcataag gttctgacaa gagtagagtc atctcgtagc
    30061 tggtcattat cttatcaagt tcggctaact gcgctaccag ttcatcatgc actgactcgt
    30121 cttcagccaa aaaatccaat aaaatttcga cttcaccctg caactcttcc atcttatgga
    30181 aggtattgta agtgtttttt aattcattca attcttgcga cgttttttgg gccgcaatat
    30241 tatcgttcca aaaatcaggt tctgtcatct tgttttccaa gatggcaatc tcttcctcta
    30301 gcccttcgag gtcaaagaga ccccctgaaa gaagctaatt tttcacgatt tgcgtcaatt
    30361 ttctgacgaa ttactgaaat gtccataaat actccttttt tacattattt cattatagca
    30421 tattttatca tttctttcca tctttttctc taatcccctt ttcatgaaaa aagaagcctt
    30481 tgggcttccc ttcttacaag acttttgctg aagtgcgagc gatttcttcc acttgaatac
    30541 catttgcttc aaatttttct ttcaaggctg gtaaatcaat tgatccatcg atttgcactt
    30601 cgataatcac cttaccatcc ttacgcggaa tattgactgt atgggagata ttcaaatttt
    30661 cttctacaat caaagaaaca atttttccaa gaacaccaac ttcatcttct gtaacaaagc
    30721 gtacacgaat cccttcttcg ccataacctg caatttcaag aaaggcttgg aaaacgtcac
    30781 ggtcagtaat aactccgtat acttgatggt tatctacgac agggagaata ctaatcttat
    30841 ttttcaacat cagataagtt gcatcttcta gactagcata gcctgagaca gtgacaacat
    30901 cgcgaatcat gacatctttt acttttgtct tattcagaag ataattcatc tcatagatag
    30961 aaagacttgt tgctttagat ggacttgctt gtgcaatggt tccctcagtc accaaaccaa
    31021 ctaattgatc attttcgata acaggcagac ggtgcaaacc ttgctctctc atcaaatctg
    31081 ctgcatgaga tactgttgta tctggactaa tataaactac cttgcgggtc ataaaatctt
    31141 taactgccat gagacttctc cttttctatt cttatcccta ttatacaatc tttttgtaaa
    31201 tctatcaaac gcttacattt ctttttcgaa attcagaaaa gtatgaataa gctagcaaaa
    31261 agagctctga aatcgagctc tgtgaatgaa ggtaagaaat tttt
//
LOCUS       DAVEHY010000025        30597 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVEHY010000025 DAVEHY010000000
VERSION     DAVEHY010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.025"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(10..1401)
                     /locus_tag="VUZ44_001398"
     CDS             complement(10..1401)
                     /locus_tag="VUZ44_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU0320306.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(1636..2013)
                     /locus_tag="VUZ44_001399"
                     /pseudo
     CDS             complement(1636..2013)
                     /locus_tag="VUZ44_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            2228..3205
                     /locus_tag="VUZ44_001400"
     CDS             2228..3205
                     /locus_tag="VUZ44_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU0320307.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVSQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            3202..4284
                     /locus_tag="VUZ44_001401"
     CDS             3202..4284
                     /locus_tag="VUZ44_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU0320308.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(4348..4902)
                     /locus_tag="VUZ44_001402"
                     /pseudo
     CDS             complement(4348..4902)
                     /locus_tag="VUZ44_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(4936..6207)
                     /locus_tag="VUZ44_001403"
                     /pseudo
     CDS             complement(4936..6207)
                     /locus_tag="VUZ44_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(6264..6622)
                     /locus_tag="VUZ44_001404"
                     /pseudo
     CDS             complement(6264..6622)
                     /locus_tag="VUZ44_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            complement(6725..6862)
                     /locus_tag="VUZ44_001405"
                     /pseudo
     CDS             complement(6725..6862)
                     /locus_tag="VUZ44_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(7246..8442)
                     /gene="tuf"
                     /locus_tag="VUZ44_001406"
     CDS             complement(7246..8442)
                     /gene="tuf"
                     /locus_tag="VUZ44_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU0320309.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(9364..10233)
                     /locus_tag="VUZ44_001407"
     CDS             complement(9364..10233)
                     /locus_tag="VUZ44_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU0320310.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKATEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(10457..11065)
                     /locus_tag="VUZ44_001408"
     CDS             complement(10457..11065)
                     /locus_tag="VUZ44_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU0320311.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(11023..12129)
                     /locus_tag="VUZ44_001409"
     CDS             complement(11023..12129)
                     /locus_tag="VUZ44_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU0320312.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(12240..12494)
                     /locus_tag="VUZ44_001410"
     CDS             complement(12240..12494)
                     /locus_tag="VUZ44_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320313.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(12852..13298)
                     /locus_tag="VUZ44_001411"
     CDS             complement(12852..13298)
                     /locus_tag="VUZ44_001411"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320314.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDVLREVPTIFECLECFFKTR"
     gene            complement(13371..13696)
                     /locus_tag="VUZ44_001412"
                     /pseudo
     CDS             complement(13371..13696)
                     /locus_tag="VUZ44_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13930..15648
                     /locus_tag="VUZ44_001413"
     CDS             13930..15648
                     /locus_tag="VUZ44_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU0320315.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESRGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            15759..16106
                     /locus_tag="VUZ44_001414"
     CDS             15759..16106
                     /locus_tag="VUZ44_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU0320316.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(16385..17221)
                     /locus_tag="VUZ44_001415"
     CDS             complement(16385..17221)
                     /locus_tag="VUZ44_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0320317.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGSRKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(17234..17863)
                     /locus_tag="VUZ44_001416"
     CDS             complement(17234..17863)
                     /locus_tag="VUZ44_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU0320318.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(17873..18514)
                     /locus_tag="VUZ44_001417"
     CDS             complement(17873..18514)
                     /locus_tag="VUZ44_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU0320319.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(18660..19889)
                     /locus_tag="VUZ44_001418"
     CDS             complement(18660..19889)
                     /locus_tag="VUZ44_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU0320320.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(19879..21045)
                     /locus_tag="VUZ44_001419"
     CDS             complement(19879..21045)
                     /locus_tag="VUZ44_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU0320321.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            21189..22202
                     /locus_tag="VUZ44_001420"
     CDS             21189..22202
                     /locus_tag="VUZ44_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU0320322.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGSNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(22247..22666)
                     /locus_tag="VUZ44_001421"
     CDS             complement(22247..22666)
                     /locus_tag="VUZ44_001421"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU0320323.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(22677..24083)
                     /gene="atpD"
                     /locus_tag="VUZ44_001422"
     CDS             complement(22677..24083)
                     /gene="atpD"
                     /locus_tag="VUZ44_001422"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU0320324.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(24169..25047)
                     /locus_tag="VUZ44_001423"
     CDS             complement(24169..25047)
                     /locus_tag="VUZ44_001423"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU0320325.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(25063..26568)
                     /locus_tag="VUZ44_001424"
     CDS             complement(25063..26568)
                     /locus_tag="VUZ44_001424"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU0320326.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(26583..27119)
                     /locus_tag="VUZ44_001425"
     CDS             complement(26583..27119)
                     /locus_tag="VUZ44_001425"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU0320327.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(27119..27613)
                     /gene="atpF"
                     /locus_tag="VUZ44_001426"
     CDS             complement(27119..27613)
                     /gene="atpF"
                     /locus_tag="VUZ44_001426"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU0320328.1"
                     /translation="MHVTVGELIGNFVLITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(27627..28343)
                     /gene="atpB"
                     /locus_tag="VUZ44_001427"
     CDS             complement(27627..28343)
                     /gene="atpB"
                     /locus_tag="VUZ44_001427"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU0320329.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(28378..28578)
                     /locus_tag="VUZ44_001428"
     CDS             complement(28378..28578)
                     /locus_tag="VUZ44_001428"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU0320330.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(28653..29660)
                     /locus_tag="VUZ44_001429"
                     /pseudo
     CDS             complement(28653..29660)
                     /locus_tag="VUZ44_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(30105..30503)
                     /locus_tag="VUZ44_001430"
     CDS             complement(30105..30503)
                     /locus_tag="VUZ44_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320331.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT         9044 a         6511 c         5499 g         9543 t
ORIGIN      
        1 ttttcttgct tattcatcac gactatagta cagctcatga gcttttaggc gagtattgag
       61 catctctggt atggtcacaa aggtataacc ttgatttttc aaatactcaa tgacccttgg
      121 caaggcattg actgtcggac tgtgaatatc atgcatcaaa acgatagagc cattagctac
      181 ttgatgctga atttctgtca aaatagatgc ttcattttta ctcttccagt ccagactatc
      241 cacatcccac atgataaagc tcaaatccaa gctattgcga atatcatctg taatagcacc
      301 ataaggtgga cgcatgagtt tagaactaga acccagcact ttagttagca catcctcagt
      361 atcagtaatc tgctttttag cttcatcaag agagagttgc gagagaatcg gatggctcca
      421 gctatggttt ccaacaacat gaccttcaga ttttatcctc ttcaccaagt cctcattccc
      481 agaaacattt ttcccaagca caaagaaagt cgctttaata tcatatttag ctagggtctc
      541 taatacctgc ggggtcgttg ctggatttgg accatcatca aaggttagag cgacaacttt
      601 ttgatgtttc ttatcaaagt aagattggta caaggccgca tctttttcga gtaagtacga
      661 agattggata acatcaaaga aagcagatac tggcaaggct atctcttcta aattttcaac
      721 cacaggactt ggataaagga taatctgact atccttgtaa tcaaaattcc atgcagacaa
      781 gtcttggtca gagaagtttt ttacaatctg ctcactctgg tcttgctcta tttttttatc
      841 ctctatgaag gaggtcaact cttttatcag ctgttcctta gccttactag catctgaaaa
      901 cagttggtca agtgtaaaag gttgcccatc ttctgttaag tgaacctttc ctagactggt
      961 cttttcagtc tcttcaatct taaaagcaac taaatcatag atttgtttgg tcacattacg
     1021 attaacgact ccctttaaac ctgactcttc ttgctctgta tagtagaaaa caagattgtc
     1081 cttactttct agcttgtcct taacatcttg atttatcagc tccctaacag aggaaatcac
     1141 tttctcccct tggagaggat aataggcaat cacttcggct tgcccctgac gaaaatgctc
     1201 cttctgattt ccctcactca attgatcatc tttctctttt ttgagcgatt caatcttttg
     1261 ctcaaaactt ttttgctggt agatcttaaa agcaataaat ccgcctaata ggcaaataga
     1321 aattgctaaa ataccaatca aagccaataa tacatgtctc gttttcccgt gtctgccacg
     1381 tcctagtcta cttttattca tatttatatc ataacaaatt tgagcaataa tttcaatgat
     1441 acaatttggc aatccacaat tcctctagca agccaaagca tcttacatca actccaacat
     1501 ccgtatctgt agagattatg tagttttcta tctatggaat ttctagtaga ttgaagctag
     1561 aatagtagac ctatacttct aaaacattgt tagaaatcga tttgactgtc ctgatcgatt
     1621 tgtcctgttc tcatttcatt ttactataaa actatgaaaa gctaggtcat ctgagaagta
     1681 attactatcg acaattgcga tagcgtatac tagtgcgatt tgtttgtagc tctggtgggt
     1741 atcaccttca cgttggcgaa ttttttctag gttttgatta acctgactgc acagataagg
     1801 ccataggcga ttgatgaaaa aattctgatg atgaacctga atttcgatga taacttggat
     1861 tccattatct aactccgcca agacgtctat actagtatag aaatcttacg ctgagtaggg
     1921 catggaaggc aagacgtgaa tgttacttcc ctccaaaatc gtcacatttt ttgctggcaa
     1981 gtccagcata tcgcggataa attgacaaat cattagttgg gctgatacct agatgtctga
     2041 gaatcctcct tttcctcctt ctattatagc acatttttaa atctaggttt gctagattct
     2101 atgcttctat ctatttattc ggaaaagaaa gctaatagct tatttgaaat tttctcctct
     2161 ctgttggata gtcccgtcta tctatgttat aatgaaagaa ggatttaaaa tcggaaaagg
     2221 agtatttatg ctaaaattag gtgtcatcgg aactggcgct atcagccatc atttcataga
     2281 agcagcccat accagtggag aataccaact ggtcgcaatc tattctagaa aactagaaac
     2341 tgcagcaacc tttgcttctc gctatcagaa tatccaacta ttcgatcaat tagaagtctt
     2401 cttcaaatct tcttttgatt tagtctatat cgccagtcca aactccttac attttgctca
     2461 ggcaaaagct gccttgtctg ctggtaaaca tgttattctc gaaaagccag ctgtctctca
     2521 accacaagaa tggtttgatt tgattcaaac agctgaaaaa aataactgtt ttatctttga
     2581 agcagctcgt aattaccacg agaaagcctt tactactatc aaaaactttt tagcagataa
     2641 gcaagtgtta ggagcagatt tcaactatgc caaatactct tccaagatgc ctgacttgtt
     2701 ggctggacaa acaccaaatg tcttttcaga ccgttttgct ggtggagccc tcatggattt
     2761 ggggatttat cccctctatg ctgctgttcg tctttttgga aaagccaatg acgcgactta
     2821 ccatgctcaa cagcttgaca atagcattga cctaaatgga gatggtatcc tcttctaccc
     2881 agactatcaa gttcacatca aggctggaaa aaacatcact tccaatcttc cttgcgagat
     2941 ttatacaaca gatggaacct tgactctcaa cacgattgag catattcgct cagctatttt
     3001 taccgaccac caaggaaatc aagtccagct tcctatccaa caggctcctc atacgatgac
     3061 tgaggaagtc gctgcatttg cacacatgat ccagcaacca gatctgaatc tctaccaaac
     3121 ttggctgtat gatgcaggct ctgttcatga gctactatat accatgcgcc agactgctgg
     3181 cattagattt gaggcagaaa aatgaaaacc aaactaccga ctgaatggca agaactgagt
     3241 gaccaactcg gtttccaaga attcaccccc attcaaactc aactatttga gccccttctt
     3301 gctggagaaa acctcctagg agtgagccaa accggaactg gtaagaccct agcgtatctc
     3361 ctaccaagtc ttctcagact acaaaagaaa aaagcccaac aactcttgat tctagcacca
     3421 aatacggaac ttgctggaca gatttttgat gtatgtaaaa cgtgggcaga agctatcgga
     3481 ttgactgctc aactcttcct ttcaggttca agtcagaaac gacaaattga acgtcttaaa
     3541 aaggggccag aaattctgat tggaactcct ggccgtatct ttgaactcat taaacttaaa
     3601 aaaatcaaga tgatgaatgt ggaaaccatc atcctggatg aatttgacca attactagat
     3661 gattctcaga ttcactttgt agaaaaaatc actcactacg cacctcgtga ccaccaactg
     3721 gtctacatga gtgccacgac caagtttgac caagaaaaga ttgtgccgaa tacacgcact
     3781 attgatctct ctgatcaaaa attggacaat atccagcatt tctacatgca ggtagaccaa
     3841 cgtcatcgag tggatatgct acgaaaactg gctcatgtag aggatttccg tggtctagtc
     3901 ttcttcaata gcctgtcaga ccttgggaat gccgaggaaa aactacagta tcgtgatata
     3961 ttggctgttt ccctcgctag tgatgttaat gttaaattta gaaaaatcat cttagaaaag
     4021 tttaaagata accaactaac cctgcttctt gcaactgacc ttttggctcg tggaattgat
     4081 atcgatagcc tagaatgtgt cgtaaacttt gatattccta gagatagcga aacctacaca
     4141 caccgtgctg gccgtactgg ccgtatgggc aaggaaggat atgttattac tctcgtcact
     4201 catccagaag aaatcaaaaa acttaaaaag tttgcaagta tccgagaaat tgtcctaaaa
     4261 aaccaagaac tctatatcaa ataaagcccc attgctctat acacatccag tgtatggagc
     4321 ttttttataa gcaattcaat tttatactca tctgctttca aaaagcattc tagtccatct
     4381 ctgattaacg atggacttta tcacctcctt ctccagtcct tgtatgacat cttgaagttg
     4441 attcatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
     4501 tttccacact tattcaatgg ggttcatctc tggtgtgtat ggaggaataa atgcaaagcc
     4561 aatattagtc ggaatcttta aggtacttga tttatgccat atagcattgt ccataacgag
     4621 taaaaaataa tcatctggat aagcttgtga aagctcttct aaaaagacgt tcatccactc
     4681 agtattacat ccaccagctc ttaagaaaaa tgattcgcct gtatgggcat caacagctcc
     4741 ataacaatag cgaaattctc gtatatagtg actatggaca tgtggaccta ctcctattgg
     4801 agaccaacaa gatcccagtt tactgattct accgaaacca gcatcatctt ggtacatcaa
     4861 gcgaacctta tgaaaaggtc tactggtttt aaagcgcttt cttgtgtatt gccccccaaa
     4921 agttagacaa ttaatttatc cgaaggattt agttctgtat tgcacagggc taagtccttt
     4981 tagttttatc ttaattttct tattgttgta ataatcaata tagtctataa tggcttgttc
     5041 caattggtta agtgatttaa atgttttctc atagccataa aacatttcgg attttaaaat
     5101 gccaaagaaa gattccatca taccgttgtc tgggctgttt cccttgcgtg acatagatgc
     5161 ttgaattccc ttactctcta ggaaccgatg ataagaatcg tgttgatatt gccagccttg
     5221 gtcactatgg agaatcgtat tctcgtagtg cttctctttg aatgcctgtt ccaacattgt
     5281 ttgtacttgt tctaaattag gcgaacaaga aagattaaaa gcaataattt cactgttaaa
     5341 gccatctaaa actggtgata agtaaagctt ttgagtactt gctggaatgg caaattctgt
     5401 cacatctgtg tagcactttt ccattgtttt agagccttca aattgtcctt gaatgagatt
     5461 ctctgccttc ttgccaacgt ctcctttatg agaagaatat tttcgtttct gtcgcatttt
     5521 agcttgtaaa ttgagtactt ttatcaagcc ttgaactctt ttatgattta ccagataacc
     5581 acgatttctt agttctaaat aaatccgacg ataagcataa tttcccttgt gttcgataaa
     5641 aatggattga atttcagctt taagctcttg gtccttatct ggtttatcta gctgtttcaa
     5701 gtgatagtag taggtcgaac gagctagttt aatggctttt agaagaatat ctaacgaaaa
     5761 ctcagtcatt aattcttgaa taatttctgt ctttcttctt tctctttttc ctccttcaat
     5821 cggagttctc ttaacttttt taggatggca ttctccgctc tcaggtactc tccctcttgt
     5881 tttctcaaca atagtatacc cgtttttcct gtattgtgct agccagttaa gaagtatcgt
     5941 acgacttggg agaccgtatt caagagaaac tctatcttta gtccagcctt catgtcagac
     6001 tttatgaatc atttcttgtt ttaaatcagg agaatagtaa cgattttttc cttttttgac
     6061 gaactctatt ccgtaacgat caatcaattt aatcatgtac ctaagattag aattgtttat
     6121 cccaaattta tttgaaagct tctctaagct atatccttgt tttctaagtt catagatctg
     6181 aactttatca tcataagtta atttcataat aaaaacaccc caaaagttag attttttctg
     6241 tctaactttt ggggtgcagt tcacttgtct tcttgaattg agactttatt tttagacgcg
     6301 acaatggttt gagcatctgc tttcctagga tgttctggac gtggcgtaat atttcgccaa
     6361 ccatggcgct tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt
     6421 ttataagcct gaaataaggc atcaattgta acaaattctc ctgcctctgt agccttcaaa
     6481 tggcgggcaa gaaagacttt ctcttgctca accgtcatat aagcatggtt acgaccacca
     6541 cgtgtttctt gaaggagaga gtcgagtccg aactcctcat attttttaca tttcgccaaa
     6601 tcgttgtttg attacagtct aaagtgtatt gaatctataa cagtacacct tggctgctaa
     6661 aatatttcta taaattagtt tgactttcct gatagagttg ttcacatctt atttcaaacc
     6721 actataaaag ttctataatc tctttataag atttgcccat cagacgaaat agaacgattt
     6781 gaaggcgttt atgatattta gctgtacgag agtcttttaa aagtgttttg atggtttgga
     6841 tttcttcttt aatcgatttc atattactat tgtataatgc tttttgattt tagtctagta
     6901 ttatactctt cgaaaatctc ttcaaaccgc gtcagcttcg ccttgtcgta tagatgttac
     6961 tgacttcgtc agttctatct acaacctaaa aacagtgttt tgagcagtct gtagctaact
     7021 ttctatagta aaatgaaata agaacaagac aaatcgatca ggacagtcaa atcgatttct
     7081 aacaatgttt tagaagtaga tgtgtactat tctagtttca atatattata gtttgctctt
     7141 tgattttcat tgagtattag ttcaatatct aaaaaaagaa ccttgccaag caagattctt
     7201 ttagtgtcta acttaaataa ttgttcttct gggaactaaa tcgaattaag cttcgatttc
     7261 tgtaaccata cctgaaccaa cagtacgtcc accctcacgg atagagaatg tagtaccttg
     7321 ttctacggcg attgggtgaa tcaactcaac gtcgattgtc acgttatcac caggcattac
     7381 catttcagta cctgctggaa gttcgattga acctgtaacg tcagtagtac ggaagtagaa
     7441 ttgtggacgg tagttgttga agaatggagt gtgacgtcca ccttcttctt tagtaaggat
     7501 gtagacttca cctttgaatt tagtgtgtgg gttgattgaa cctggtttag cgataacttg
     7561 tccacgttcg atttcatcac gttgaacacc acgaagaagg acacctacgt tatctccagc
     7621 aagaccttcg tcaagttgtt tacggaacat ttcaacacca gtaacaactg ctttttgagt
     7681 ttcttctttg ataccaacga tttcgatttc gtcgttgact ttaacgatac cacggtcgat
     7741 acgtcctgaa gcaactgtac cacgtccagt gattgagaat acgtcctcga ctggaagaag
     7801 caatggtttg tcagtgtcac gttctggttc tgggatatac tcatcaactg tgttcatcaa
     7861 ttccataacg atgtcttcgt atttagagtc accttcaaga gctttaagtg ctgaaccttg
     7921 gataactgga agatcgtcac ctgggaagtc gtattctgac aataggtcac ggatttccat
     7981 ttcaaccaat tcaagcaatt cttcgtcgtc aaccaagtca actttgttca tgaagacgat
     8041 aaggtgttta acaccaacct gacgtgaaag aaggatgtgc tcacgagttt gtggcattgg
     8101 tccgtcagtt gaagctacta caaggatagc tccgtccatt tgagcagcac cagtgatcat
     8161 gtttttaacg tagtccgcgt gtcctggagc gtcgatgtga gcgtagtgac gtttttcagt
     8221 ttcgtactca acgtgcgcag tgttgatagt gataccgcgt tcgcgttctt ctggagcagc
     8281 atcgatagac gcatagtctt taggttggtt aactgatgaa ggcaagcgac gtgccaaaac
     8341 agttgtgata gctgcagtta gggtagtttt accgtggtca acgtgtccga tagtaccaat
     8401 gttaacgtgt ggtttactac gatcgtattt ttcttttgcc atttgagtaa aagcctccaa
     8461 taaaatatat tttatagata gacagtaggc aatacagtct aactttcctt actattttat
     8521 caaatttcag ctaaattgca agtgttttac aacgtttttg tgaattattc ttggtaaaaa
     8581 tttaactaat taatagaaag tactaaatag acttatcctt caaggagttt tcagcattat
     8641 ccatccactc acttgctgaa aatgtaaaca gtctctggtt tatatagtaa aatgaaacaa
     8701 gaatagggca aatcgttcag gacagtcaaa tcgatttcta acaatgtttt agaagtagat
     8761 gtgtactatt ctagtttcaa tctactatac aacctcaaaa ctgtgttttg aacaacctgc
     8821 ggctagcttc ttagtttgcc ctttgatttt cattgagtat aaaattgcag ataaaacgat
     8881 aacaatcata ggactcagca gagtcaatgt aggtcgaaga atagcccccc taatcgctta
     8941 ttttatagta aaatgaaata gaaactgaac attttgttga ggaaggtaaa tcaattcctc
     9001 acaatgtttg agaaagaagg gaggactatt ccaacttcaa cccactataa agcagactta
     9061 caagataggg aacccatctc cgataatatt ccgataatat atagtagaat gaaaactgca
     9121 caatttgatt ggagaattca aaccaatttc tcacaatgtt ttagaaacaa gggtctatta
     9181 tttcaactgc aacctactat agtccattga agctggaata gcccactgag acttctaaac
     9241 cactgctgga gaggagtttg tttagagttt ctttcatttc cctaaaaaat caaaaagaga
     9301 gaaccagtct gatcctctct tacttataga tggtgctcac tcaaatgtta aaggagctat
     9361 ttcttagaga taaaggaatt tgaatacagc tactgccgca attgctgctg cgataggtgc
     9421 tactactggt acccaagaat accaccattt tgaatcgcct ttatgctcac caagaactga
     9481 tttgggaagg aaagcatgaa ggagacgtgg tcccaagtca cgggctgggt tcaaggcagg
     9541 tcctgtaggt cctccaagtg atgttaccaa agccataacg aggaatccaa gtgccaagtg
     9601 agccacagaa agtcctgaag cagtgtgtgg agccacctgt gctttaatag ccaagtcaga
     9661 aaaatcaact gtttgtcctg cttctgttgc cttttgtttc atgaattgaa gcacttcagc
     9721 accaaagaag tttttagtca aaccaagagc tgcaaagaac aaaacaaatg aaccaacaaa
     9781 ctcattaatc aaaccattga cagttgctgc atagcgactt tcttttgtac catggtcaat
     9841 acttgaaata gttgagaaag ttcccaagat gttatttggg ttttcagttt tcaagtagaa
     9901 tggacggtat gttgccacaa ctaaggcttg gccaaagata gcccccaaga cttgcgcgat
     9961 aatgtaaggt accacttgtg cccaagggaa aagaccgcta actgcaagcc ctagagtgaa
    10021 agcagggttg atgtgattcc cagatacgtt accaaacatc aaggctggga tcataacccc
    10081 cataccataa ccaacagcga tgacgatcca gccactttgg tgacctttcg tacctttaag
    10141 ttcaacgttg gcaactgcac cattcccaag aatgatcaaa atggcagttc ccaaaaattc
    10201 agtggcatac ttcagtgccc atgtgaaatc catttgctag attctcctta aaatttttta
    10261 gatattcctt attttatcaa tttttaccct atttagcaac tgatttctgg aaatattttt
    10321 aaaaaaatag gattcatagt ttcccagttc aacagacttg taagcgtttt tattctttac
    10381 gaaagacctc gttctcaaaa ccaggaaaaa agcccacatc tgtgagcttt tcctggttcc
    10441 tagattctaa aatctattat ttttcatctt cttttttctt gaaaaatcct aatcctagac
    10501 cagctaacaa ggtcatgata ccagcactag ccaaggtagc attagcttct gtacctgtgt
    10561 ttggcaattc ctctctctta cctgtctcat aagtcggaac ttctgggtct ggattcactg
    10621 gagtttcagt ttttggagta cctggttctg gagttggttt atctggtgtt ggagtctctt
    10681 gatttggtag ttctgggttt ggtgtcggaa cacttggatg ctctggattt ggttgtggga
    10741 ttggtttttc tggtgttgat aaacggtcat accttaccgt tatttcttta tcactagagt
    10801 ctgacgtaac ttcttgtgat tcaactgttg gaatatctgg atctttgtac ttgtcaatct
    10861 taccagatat aacctcgtcc cagtttcctg ttgtccattc accgtaggtt acaactcccg
    10921 tgaccttgtt ctcagttttt gtacggctta aggttacagg ttgaacaaca tcttctttta
    10981 cattttggtt cgtaacttta tcaacgtaat gaatgatacg cgttatagtc ttcgtctcag
    11041 tagaggttgc tgttttggga accactgttt cctcaacatt ctcacggtag taatagtcaa
    11101 ctgttgcacc gtcttctggt acgcatttgc aggagttgct accaaggtgt atgttgtttt
    11161 ccttgtgata actcggtctt ctttgtcctc agttgttgtt ttcccttcaa tagtttttga
    11221 ttctgtggta tactcagaac ctatcgctaa atcagctttt ataacagact ctaccaactt
    11281 ctcttgccta ccttctttat agtaattggc tgttactgta gcagtggttg gcgcttcgct
    11341 ttctctataa actaaggtca ctgttctacc ttcgcttaca atattcccag ttaaacttgc
    11401 agaatttgta tctgcttctt taaaagtata atattttccg tcagtagtag tcatgctact
    11461 gagtttttta tctgtgacat tatagctggt accaatcagt tgttttttat tggtaatgta
    11521 ggttccgtca ctttcttttt ctccaattcc agtatcattt ttcaatgata gcaaacgccc
    11581 ttgttcatca acatagcgaa ctttcacatt ttctgagatt agttctgcca attctgaggt
    11641 ttttttcttt ttcttgattt cttcggttat tttccctttc tcttcttcgg gaatatttag
    11701 ttttggaatg attttttcaa caacggttcg tgatggttcc acagtatctt ggatgactga
    11761 aaagtcagct agaattggga gattatactg aacacggtga ctttgagtgt ttactcctac
    11821 tctttcatta ttctctgaaa atacttgtac ggtataagaa acaacatctt ttcctaatag
    11881 aacatcccca gtagagaaat agccgccttt tcctagtttg ctatctccag agcccacttc
    11941 tttcctaatc ttatcagata gttttttacc agtcagtaca ttcgttcgca caatcccttt
    12001 gtctacccct acaaagtggg agaacttttt gaactcttca gaaccagatc tagcccaacc
    12061 attattaagg gcatttgctt ttgtatttgt attctctctc aaaagtttgg cgattagaat
    12121 tatattcatc ggcacttaga gttgctgcta tatctgactc ttgaatacca acttccttac
    12181 taccatttct agcggcagta tatgtgtatt tatctgtttc tacttctagc tgattatcct
    12241 taacatgata ggtaattttc tcctggtata agagtcttca gtagtttata tactctgtca
    12301 tcatctttag ctttagaagc agctgagttt agccaagttg gggtattagg agtatcttta
    12361 tcagcctgtt tcaagacatt attcaagtca tttgctagcc tattggttat cctcactgtg
    12421 aaagttttct tccagtctga accactttta ttagacttag atatgctcat gaaatcctgg
    12481 tcaacattca acacaatatc gccttgtttt ttagcatctt ccgttgcttc tgcttcaaat
    12541 tgatcatgga gtttttgttg ctctggtgta tagttttttt atttacacga tttaatgtac
    12601 tattttttat tttagtatta agaactccat taatacgatt tttaaactct gcttcaaaaa
    12661 atcccttaat ttgttggtgc gcaagttcaa cattcaaacc tttcttatac aagtcttcat
    12721 tctgatacaa gtcttcattc tgaacgattt cggctacacg gtgaatggtt tgattgtata
    12781 ccgtcttctc ttaaccagca gtatccttag ttttaatgac tactcgatag gttcctttag
    12841 aaccgttata gtcatctagt tttaaaaaag cattccaaac attcaaaaat agttggaact
    12901 tcccttaata catccgtcac tttctttttc aagatagccc aagcttgctc aataggattc
    12961 aaatccggtg aataaggtgg tagaggtaag aaaaagtgtt tatcttggat gcagagttca
    13021 tccaaaatgt tcttgggatg aaaaccagca ttgcccatga caataacatg aggtgtcttc
    13081 aaagcaggta ggagttgcgt tttgaaccac tccacaaaga aatcgcttgt catgcttttc
    13141 ttgtaaatca tgggagctat aaactctccg tctacttgtc ctgcaacaat tgaagttcgc
    13201 tcaaaacgac gtccgctaat cttttcatag actttctccc ctctaggagc ccctgcataa
    13261 ggacgataga gatagcggtc gattcctgtt tcatcaatat aaacaggtgc taggtgcttt
    13321 aaactattaa aattcttaag aaataaggct acttttctgg gtcttgttcc ttaaagctcg
    13381 tcatcttttt ttaaagtgac cttaatctgc tttaaagctg cccatactga aggaacagca
    13441 caatcaaaat gtgccgcaat ttcccgtaaa aaagcatctg gatgagcctc tacaaaggct
    13501 ttcaattcct ctaaaggaat ctttcggttt ttgacgactc gctttttcct ctctatgtgt
    13561 tcttgttcac gtctttcttt tcccacgtga agagagttct gacgccaaca ccaaaaaact
    13621 tggctgcctc gacatggctg tgcccctctt tgatgtaatc taatgctcgc tgtttaaaat
    13681 cagtactata tgccatagct ttattataat atgcttgttt aaaactaagt aactatatca
    13741 atgttttgtt atgagaagac ttactttttt tactgaaatt gaatttttcc tagcctcaac
    13801 atcatataac cccaaaattc aatctgacct ggtttgaaga gatgttcgaa gcagataagg
    13861 ttttactaaa actaaaaaaa atgatataat caaactgatt aaatgtttta aaaataaagg
    13921 agaatttgaa tgtcttacca agaaaattac cagaaatggg ttgattttgt ggagcttcct
    13981 gactaccttc gtcaagattt ggaaaatatg gacgaaaaaa ctaaggaaga tgccttctat
    14041 acaaatcttg aatttggtac tgcaggtatg cgtggcttgg ttggtgctgg tacaaaccgt
    14101 atcaacatct acgttgttcg ccaagctact gaaggattgg ctcgtttgat tgagtcaaga
    14161 ggtggaaacg agaaagaacg cggtgtagca attgcctacg atagccgtca cttctcacct
    14221 gagtttgcct ttgaatctgc ggcagttctt gctaaacacg gcatcaaatc ttacgtattt
    14281 gaaagccttc gtccgactcc agaactatca tttgcagttc gtcatctcaa ctgtttcgca
    14341 ggtatcatgg tcacagccag ccacaaccct gctccattta acggttacaa ggtttacggt
    14401 gaagacggtg gacaaatgcc tccacacgat gcggacgctt tgactactta tatccgtgca
    14461 atcgaaaacc catttgcagt tgaagttgct gatgtggaaa ctgaaaaagc ttctggcttg
    14521 attgaagtta tcggcgaagc tgttgacgta gaatacctta aagaggttaa ggacgtaaac
    14581 atcaacccag ccttgattga agaatttggt aaagacatga agattgtcta cacaccactt
    14641 catggtactg gtgaaatgtt ggctcgtcgt gctcttgccc aagcaggatt tgactctgtt
    14701 caagttgttg aagcgcaagc aactgctgac ccagacttct caactgtaac atctccaaac
    14761 ccagaaagcc aagcagcctt tgcccttgct gaagaacttg gtcgtcaagt tggtgcagat
    14821 gttcttgtcg caactgaccc agacgctgac cgtgttggtg ttgaagttct tcaaaaagat
    14881 ggtagctacc tcaacctttc aggtaaccaa atcggtgcta tcatggctaa atacatcttg
    14941 gaagctcaca aaaacgctgg aactcttcct gaaaatgccg ctctctgcaa atctatcgtt
    15001 tcaactgact tggtaacgaa gattgctgaa agctacggcg caactatgtt caacgtcttg
    15061 acaggtttca aatttatcgc tgaaaaaatc caagaattcg aagaaaaaca caaccacact
    15121 tacatgatgg gatttgaaga aagcttcggt tacttgatta aaccatttgt acgtgataaa
    15181 gatgccatcc aagccgttct tgtcgttgct gaacttgctg cctactaccg ttctcgtggt
    15241 ttgacacttg ctgacggtat cgaagaaatc tataaagaat atggctacta cgcagaaaaa
    15301 acaatctctg ttactctttc aggtgtcgat ggtgctgaac aaatcaaagc gattatggct
    15361 aaattccgca acaatgctcc aacagaatgg aacgcaacag ctatcactgt cgtagaagac
    15421 ttcaaggcac aaactgctac tgttgctgac ggtactgtta caaacttgac aactcctcca
    15481 agtgatgtgt tgaaatacac acttgctgac ggttcatgga ttgccgttcg cccttcaggt
    15541 acagaaccaa aaatcaagtt ctacattgca gttgtagggg aaaccaacga agaatcacaa
    15601 gctaagatta ctaacatcga agcagaaatc aatgcatttg taaaataaag acctataaaa
    15661 gatgagacca accaacctca tcttttttcg tatcaaatct aagcaatttt agaaacttta
    15721 tggcatacta gacttatcaa tgaaagcgag gtaatctcat ggaacaattt ttagataaca
    15781 tcaaagacct tgaagtcact acagttgtgc gtgcgcaaga agctcttgat aaaaaagaaa
    15841 ctgcaacctt ctttatcggt cgcaaaactt gcccttactg ccgtaaattt gcaggtacat
    15901 tgtcaggtgt cgtagctgaa accaaagctc acatttactt catcaatagt gaagaaccaa
    15961 gccaactcaa tgatttgcaa gcattccgct cacgttatgg aatcccaact gtaccaggtt
    16021 ttattcatat tacagatgga caaatcaacg tccgttgcga ctcttcaatg tcagcacaag
    16081 aaatcaaaga tttcgcagga ttgtaaaaaa tcagctaaca agtcttaaaa tcacaaaaac
    16141 gcataatgta aggtgcaaaa accttgatat tatgcgtttt attgttccta aaacagttac
    16201 atcagcattt cattacagaa cattttaatt ttggaagtca aatcaatttt taacaatgtt
    16261 ttagaaatca cagtgggcta ttccatattc aattatccag attcaatcgc tattatcgtt
    16321 ttcctagatt acaaaaaaaa ctacgttttg ctaatcaaaa cgtagtctca gccactattt
    16381 tatcttactg tccttctttt acttctttgg ttgctacatc ttctccaaac catttttggc
    16441 tgatttcttg gaacttgccg tccttgtaaa gactagaaaa agcttcattt atcttcttaa
    16501 ccaaggttgt atcttcctta cgggatccaa ccgcaaaagc ttctgtttct agtccaactg
    16561 taaagacatt ataatcgttt aaaacacctt ctgcttctaa ataatagttt gcatagacac
    16621 ggtcaatcaa tagaccatca attcgatcgt ttttcaaatc aatcaaggct tcattaaagg
    16681 tttggtattg attcgcttcc ttattagcga caatattctt caaaatttct ggatttgctt
    16741 caaagtccgc ataaccagat gaaccagctt gagctcctaa tgtctttcca gtcatatcct
    16801 ttgcagtcgt gataccagat gatttcttcg taaccaatac ctgctcattc ttcatatatg
    16861 agttactgaa agccaccttt tcacggcgtt cgtctgtagc ggaatagcca ttccaaatca
    16921 gatcaatcgt tccttttgtc aattcagctt ctttcaaatc ccaatcaatc ggttgccaat
    16981 ttaccgtgat tccgtatttt tcaaaaacag ctgtagctaa atcaatatca aatcctgcat
    17041 aagaaccatc tttctgagca aatcccattg gaacaaaagt actatcaaat ccaatagtaa
    17101 tagacttgtt agactggtac tttgaccaat tatctccact agtttcgcta gaatttttcc
    17161 cacaagctac taagaacaaa gcagtcatca gactgactaa tacaagcatc cattttttca
    17221 tccatttttc ctcctattta ggttctactt tcaataatac atctgcgata ttttcagcaa
    17281 actgcaaatc atgggtaacc acaatctggg tcatcccaag ttccctattt tgcaagatta
    17341 gcttctccac ttccaaacgt aattctggat ccagggcaga agttggttca tcgtagccaa
    17401 tgatttctgg gtcaatcatc atagcacgcg ccaaagccac ccgctgcttt tgcccaccag
    17461 atagtgagaa aggataggcc tctgcgtgtc ctcctagtcc taactgttcc aagagcccac
    17521 tcgccttctt ctcagcctct tcctgcttca ttcccatggt cttcacaggc gataaagtca
    17581 aattttccag aactgataga tgaggaaata gttgaaaatc ttggaagaca aatcccagta
    17641 ggttgcgctt ctgcaattca tccagctcta aaggttgtcc attataaaag atttgccctg
    17701 aatcaatggt ttcaagacct gcaagcatac gtaaaagagt tgtcttacct ccaccagaag
    17761 gtccaacgat agccaggatt tgcttttcag gaatacttag actgaaatta gacaggattt
    17821 gtttgtctcc aaagacttta ttgatatttc gtaattctaa catggcagcc tcctatctat
    17881 aataactata cttcttctca acttttttgg aaataattgt cacaatccca atcaaaatca
    17941 aataaatggc tcctgccaag aacataggaa ctagactagc atcgcggtta gcagctgttc
    18001 gactagccaa gataaggtct gaaattccga gagcatagac caaagaagta tccttgacca
    18061 aactcataac ttcattaaag acactaggaa gaacaatctt ggtcacttgg ggcaagataa
    18121 tatagcgcac tctgtcaaaa gggctaaact ttaagacctt ggcagcctca tactgtcctc
    18181 ttggaatagt gtcaattccc ccacggaaaa tttctgcaaa gtaagctgca tagttgagaa
    18241 caaaggcaat aatagctgca ggaaggcggt ctaaacgaat cccaatactt gggagcacat
    18301 aatagataaa aatcagttgc aagagtaagg gggttcctcg cataacccag atgtaaatgt
    18361 taatcagata atggaggggc ttccaatgga cttgcaaggc aaaggcaatc aaaacgccca
    18421 agggaatcga aaatagcaag accagtgcaa agacctgtac agtcgtgctc gcaccattca
    18481 gtaaactcgg taatatctca aataaataag acatactgca cctcctaaaa gtaattgttc
    18541 ctattatagc atgaataaac aagattacca agtatttttg taaaaagatt ctaccatata
    18601 caaataaaaa ccgtagctat caaaagagat aaactacagt tctatatgtt taaacattct
    18661 tacaatctct caaacagttc ttgcatttgc acatcatctg gaaccagttt taagtaagtg
    18721 tgagcatgga cttttgcttc ttcaaaatgt cccaattcac gcaagagata gatatagtgt
    18781 tccagaaatt ctggattgtc cttcaaatct cctgtcaact cttgataatg ctcataagca
    18841 gtatccaaat cgtccatttc ttgataagaa cgagcaatca tccacttggt caaaagattt
    18901 tctggctcct cactctgcaa gtctagaata tcctcataac gctcctgctc cagataaata
    18961 gtggctaaac gaagcaagat ttcttctgta tcctcagcgt cttcttttgc agtaaggaga
    19021 taattttctg caccactagc atcatgcaat tcataagaaa attgtgaagc agctagcaag
    19081 aggcgagttt caaagggatt tttctctaat ccttgcttag cgatacgcag ggcttcttga
    19141 acttgatgtt ccttatgtaa agcctgactg tacccatact catagccttc aaagtcagga
    19201 gaaatggtat caagctgctt aaagtagagg gtggcttttt gatattcttc ttgatcaaaa
    19261 taaagactgg ccaactcaaa agctgttaag tcatcgtatt ctaactccag ggctttttct
    19321 aaaaactcag tagccgtttc aaatttccct aactgagcat aggcaaagcc aattcgttga
    19381 taggtggaaa tgcccgtttg ctcataaatc gagcgattat ctaactgggc ataggcttga
    19441 atagccgctt ggtaattttc caactcacta tccaactctg ccaaacccaa tatcaagaga
    19501 gaatcctctg agtaggtcaa ggcctccaat aatttctcac gtgccacatc tgtcaaacct
    19561 tccagctggt aaaggtctgc cttcaaaacc aaagacgaga cataccagtc actgtcagct
    19621 tggatttcct caagataggt aaaggcttct tctatttgac catcctcgct agcaattgca
    19681 gctagattaa gatgaacctc tggaaaatcc tctacaattt tcaggtaaat ttccttggcc
    19741 tgaggataga aaccaatccc ttcaagataa gttgccaact catacagaag attacttgaa
    19801 tcattttcta aagctttggc gaaataatgc tcagccttag ttaaatcttg ctcctccaaa
    19861 gcctgtaaca tctgttgact attgttcact cttgacttcc tcaccctcta attcatatag
    19921 accactgact accttatacc attcgaaaat ggctgaaatg acaaccttag cagaggcata
    19981 aaccggaata ccaagtaaaa ctccccagat accaaacata gatcctgaag ttaacaaaac
    20041 aaagagaaca ttaatagggt ggatgtttaa ttgacttccc aaaatcaatg gagagacaaa
    20101 acggccttca atagtttgtt ctacgataaa gacaatcact actttcaaaa gcatgactgg
    20161 accagcaatc aaacccaata ctagagcagg aagcatggct agaaagctac caagataagg
    20221 gaccagattt aaaataccag cagtaacccc cagcgtaacc gcatagcgta gaccaataat
    20281 cttgaagaag atgataaaca ttactgctac aataatagcc actgtcactt gccctcgaac
    20341 atagttggac aactgttgat tcacatctga tagaacttgt ccaacaggtt ccttcaattt
    20401 tcttggaatg aattgggtca aatagttacg caagcctttc ccatcacgca agagataaaa
    20461 gagcatgaaa ggaacgataa tcaaggcaac aatcacttga gaagccccgc taataaaggc
    20521 actcacccag ttgactgcct gagatgaaac cttacttgcc aaaactgtag cctggctaga
    20581 aaaattggtc aaaacttgct ctaattgagg tctgaaatca tctggcagat gctgggctac
    20641 caatccatta acaatcctat ctatatcttc taagtaaaca ggaacgtttc ttgcaaaggt
    20701 caaaacctga cgttgcagat ttggaatggc gactgccaag ccccaaatga taaagagagc
    20761 gatgataaca aagacaatag tgatagctat aacacgatta accttatgct tctccatcca
    20821 atcaacaata ggattcaaca aataatataa caaaccagac aaaatgactg gcaacatcac
    20881 aactgctaaa aagtctaaaa caggtgaaaa tagaaaacta atcttactta aaataaaaag
    20941 attcagtccc aataataagg ttactaaaaa taccgtaatt gccttgttat ctaaaaacca
    21001 cttgaaaaac caagataggc taaaatgttt ctctttttgc tccataaata cttcctttct
    21061 attgttctct cattatacca tttttgaaac aaaataactc ttttttaaag tgcttacatc
    21121 taattggata tctttaattt acttgttttt gtgatataat agtcttatct ttacacagag
    21181 gtatagtaat gaaagaaact gtttattttg gaacttatac acgtcgtact tctcaaggga
    21241 tttacaaggc agactttgat acagaaactg gtcagctttc aaatctagaa ctttttgcag
    21301 ctgagccaag tccaacctac cttgcctttg accagcacca acatttatac actgttggta
    21361 gccaagacga taagggggga attgcagcct atcaaactga cgggactgtg ttaaatcatg
    21421 ttgttgaaga aggagctccc cactgttatg ttgctgtcga tgaaaagcgt gatttggttt
    21481 acgcagctaa ctatcacaag ggacaagtcc ttgtttataa acgccaggaa gatggtagtc
    21541 ttctacttag tgatatggat caacacagtg gccaaggtcc acatgaaaat caagcttccc
    21601 cccatgttca ctatacagat ttaacacctg accactatct agtgacctgc gacttgggaa
    21661 ctgaccaagt catcacctat gacctcgatc aagaaggaaa attatctaag ctctatacct
    21721 atcacagcaa gccaggagca ggctcacgcc atatcatttt ccataaccac tataaaatcg
    21781 cttatctcat ttgtgaactc aatagtacta tcgaagtttt aatctacgat ggcgttggcg
    21841 aatttgaacg tatgcaggtc atttcaactt taccggaagc ttacgaaggc tctaatggaa
    21901 ccgctgctat tcatctctct aaagacggta aatacctcta cgcttctaac cgtggccatg
    21961 attctatcgc agtatatacc atccttgcgg acggtagctt agagttatta gaaatcgttc
    22021 caacgcatgg tcagactcca cgtgattttg atttgacacc cgaccaaaaa tttctcattg
    22081 ttgtccatca agactctgac aatgcaactg tctttaaacg taattgtgac aatggtcgtc
    22141 tagcagaact ctccaacgac ttccatgttc ccgaagcagt ctgcatccgt tttgctcctt
    22201 aaaacaccat aaaaaatgaa cttggtattt tcaagttcat tttttcttat agtctatttc
    22261 cgacattaat acggttaatg gcacgttgca aagcaatctt agcacgacgt tcttggtcaa
    22321 tcaaatgttt gtcttgtgct tcttcaattg cacgttctgc acgaagtttg gcacgttctg
    22381 cacgactgat atcgatatca cgagcacgtt ctgcagagtc agcgacgatt gtaatcatat
    22441 cattggcaat ttcaataacg ccaccgttta ctgcaatcca gttcacgtga tctttatcat
    22501 cgatacgttt tacctttact tcatcaactg ctaaaaccgc aatcatattt tcatgtcgtg
    22561 gcaagatccc catctcacca tccagagttc gaaccgatac atagctggca tggtgatcat
    22621 agacgagacc atctggtgtc acgatctgga cagttaactg agccataggt cacctcttaa
    22681 aatcccattt tttcagcttt tgcaatcaca tcttcgatag aacctacacc acggaaggca
    22741 tcttctggca agtggtcgta tttaccatca aggatttcct taaagccacg tacagtttca
    22801 gcaactggaa cataagaacc tggctgacca gtaaattgtt ccgcaacatt gaagttttgt
    22861 gacaagaaga actggatacg acgggcgcga gcaaccaagg tcttttcttc atcagaaagc
    22921 tcatccatac caaggatagc aatgatatct tgcaattcat ggtaacgttg aaggacacgt
    22981 tttacttcag cagcaactgc atagtgctct tctccaacga tttcaggtgc caaggcacgt
    23041 gagcttgaag caagtgggtc aacggctggg tagataccca attgtaccaa tttacgttcc
    23101 aagtttgttg ttgaatccaa gtgagcgaag gctgttgctg gcgctgggtc agtatagtca
    23161 tccgctggca catagatagc ctggatagag gttacagaac ccttcttggt tgatgtgata
    23221 cgttcttgca attgacccat ttccgtagca agtgttggtt ggtaaccaac ggctgatggc
    23281 atacgaccca aaagggcaga tacttctgaa ccagcctgag tgaaacggaa gatattatcg
    23341 ataaagagaa gcacgtcttg gccttccaca tcacggaagt attcagcgat tgtcaaacca
    23401 gtaagggcaa cacgcatacg tgctcctggt ggctcattca tctgaccaaa gaccatggct
    23461 gttttctcga taacgcctga ttctttcatt tcccagtaaa ggtcattccc ctcacgagta
    23521 cgttccccaa caccagtaaa tactgaaata ccaccgtgct cttgggcaat gttgtgaatc
    23581 aattcttgga ttaagacggt tttaccaact ccggcaccac cgaaaagtcc aactttacca
    23641 cctttaaggt aaggggcaag aaggtcaata accttgatcc ctgtttcaag gatttcagaa
    23701 gaggtagaca actcatcaaa agttggagct tttttatgaa ttggctgacg ctctgcgtct
    23761 tctgtaaaag gagcttccaa atcaatggta tctcccaaaa cgttgaagac acgtcccaaa
    23821 gtttctttac ctactggtac agagattgga cgacctgtgt ccaatacttc cattccacga
    23881 gtcaacccat ctgttgattc catggcgata gtacgaacca taccatctcc taactccaag
    23941 gctacttcaa ggacgatttt tgtttttctt tcgtcatttt tgtagacgac aagtgcattg
    24001 ttaatctcag gaagtttttc ccctgctgca aacaaaacgt ctacaacggg accgataacc
    24061 tgagcaattt tacctgaact catctccttc tcctattcta tataagatac tgtcggttcc
    24121 tagctcaact aggtcctaag ttcattttca tacgagctgg actagagcct attctaaggc
    24181 actagcacct gctacgattt ctgtaatttc ttgtgtaatc gccgcctgtc tggcacggtt
    24241 atactgaatt gtcaaatcat tgatgacttt cttagcatta tctgtcgctg tttgcatggc
    24301 tgtcataccc gcagcattct cagctgtctt ggcatcgata atggcaccgt aaatcatact
    24361 ttctgcaaac tgaggcaaca actgctccag aatttcttct cggctggttt ccaattcaaa
    24421 agtcaagctg tactcttcat ccgcctcatt tggatccaag tcaacaatcg gaagcatttg
    24481 ttccacacgc atttgactgg ttagcgtatt gacatggtgg ttgtagcaaa cataaagctc
    24541 atcaaagagt tcattttggt acatttcaac agtttttgaa ataatcttac gaacttgatc
    24601 aaagctaggt tggtctgcca agccacgtaa ttcataaagt ggttgaatac cgcgagcctt
    24661 aaagaaatca gctcccatcc caccgataca gatcatttca aaacctttac cgtctgggtg
    24721 gtattcttct ttcaactcca taacagcttt caaaatagag gaattataac ctccaaccaa
    24781 accgcggtct gaagtgataa cgatatagcc tgtcttcttc acagaacggc taatcaacat
    24841 cggattagtt gaagcaccag ctccattacc atgaaggata tctgtcaaaa gtttacgcac
    24901 tttctgagcg taaacttgga agttgcgagc agcttcttca gagcgaccta acttagcagc
    24961 cgataccatt tgcatagcat tagtgatttg actcgtattt tttgttgagg cgatttttgt
    25021 tttaatatca tttagagaca ctgccatctg acacctctat tcttattgga agctagattg
    25081 attgagaaac tctgtaatcg cagcatccaa gactgcttct tctggcaagt cttttgtatc
    25141 acgaatggtt tccaaaatct ctggatgttg agcatcaaag aaggcatgga actcttcctc
    25201 gaaacgaaca atatcatcta ctggaacagt atccaagaaa ccatgtgtca aagcataaag
    25261 aatggttact tgtttctcaa caggtaatgg tttgtgaaca ggttgtttca agacctcaac
    25321 ggtacgacgt ccacggttca acttagcctg tgttgctgcg tccaagtcag aaccaaactt
    25381 agtaaaggct tccaactcac ggtatgaagc aaggtcgata cgaagtgtac cagcaacctt
    25441 cttcatggct ttgatttgtg cagaaccacc tacacgagat acagatgaac ccgcatcgat
    25501 ggctggacga atacctgcat tgaagaggcc atcgccaagg aagatttgtc catcagtgat
    25561 agaaatcacg ttggttgcga tataggctga gatatctcct gcttgtgtct cgataaatgg
    25621 tagggctgta attgatccac caccaagttc atcagaaact ttagctgagc gctcaagcaa
    25681 acggctgtgg agatagaaaa catcccctgg gaaggcttca cgacctggag gacgacgaag
    25741 caagagcgat agttcacgat aagctaccgc ttgttttgat agatcatcgt atacaatcaa
    25801 aacatgctta ccttgataca taaattcttc cgccatagca accccagtat aaggagctag
    25861 gaagagcaat ggagatggtt gtgaagcaga ggctgtcaca acgattgtgt agtccaaggc
    25921 accgtactga cgaagtgttt ctacttgcgt acgaactgtt gattcttttt gtccaatcgc
    25981 gacgtagata cagatcatat cttgatcttt ttggttcaag attgtatcaa tcgcaatggt
    26041 tgttttccct gtctgacggt caccgataat caactcacgt tgaccacgac caatcggtac
    26101 aagggcgtca atagctttca aaccagtttg caatggttct gaaacagact tacgttgcat
    26161 aacaccagga gctggtgctt ctactggacg agttttatca gtgtggattt ctccaagacc
    26221 gtcaactgga cgaccaagcg gatccacaac acgaccaatc agactttcac ctacagggac
    26281 ttccatgatt ttccctgtac ggcggattgt atcgccttca cggatatctg taaagtcacc
    26341 taggatgata ataccaacgt ctgttgactc caagttttga gccataccat aagagccgtt
    26401 ttcaaaattc aacaactctc cactcatgac attttcaagg ccatgagcac gcgcgatacc
    26461 gtccccgata taggttacaa cacctgtttc agtcacatca aaattgggtt tgaaattttc
    26521 aatttgttgc ttaattaaag cgctgatttc ttgtgcgtta attgccaaaa gaacaccact
    26581 ttctatttca aattttcttt aacaacttta agttgttgtt taatactcac atcaattgtc
    26641 ttgtgattgg caaaaatgac aaaaccacca atgagacttt catcgatttg ttcttttaca
    26701 ctccttactt tcagagacat ttttttctca atcaaaggga gcaaacgagt cttctgttca
    26761 tcagttagag gatgagcaga cgtaatcgtc acttcaaatc gatttgtttc tttttcaagt
    26821 cggttcaagc aatctacaag cacatcataa aaaagatttg ctctgtgatt gtaggccaga
    26881 acctggataa agttttgtaa taaaggcgac acagaatctt ggaaaaaagc aattgttttt
    26941 tccttatccg actcgtctac tgccacttgt tttaaaaaag aaggcagacc tgttttttca
    27001 acaacttgct tgatttgagt caagtctgaa aagatacggt cttcttctcc tttttcaagt
    27061 accaattgga caaaaggcat gctgtatttt tcaattacct ttactgtttt cttgtccatt
    27121 aagcttctcc tagctgatcg atatactgat caatgagtgc tttatgggca tgactgtcaa
    27181 ggttttgtga gatgatttta ccagctaagc tgatggtcaa atctgcgacc tcacccttaa
    27241 cactctgtaa agcttctact ttattttgag caatttcttg attggctttt tcttttaagt
    27301 gtcctgcttc tagtttagca tctgctaaga tattagcctt actttgctca gctgtttcct
    27361 ttgcattttc aatgattgtc ttagcttctt tacggctacc agccaattca tcttcgcgtt
    27421 tttgagccaa tacttctgct ttttgacggg cttcttcagc tctgtcaata tctgaagcaa
    27481 ttttttcagc tctttcttcg aaaatgcctg taatattaga ccatgcaaat tttttaatca
    27541 agactagcaa aagaataaaa gagccagtga ttaaaacaaa attaccaatt aattcaccta
    27601 ctgttacgtg catcagttac tcctttctat tcctcttcaa tattaatctt attccctaaa
    27661 tacacagatg tcaaaagagt aaaaacataa gcttggatgc aggaaataaa gacagaaaat
    27721 gcagtccaag ccaaattagc tccaaaggct actggatacc aataaatagc ttggtgggaa
    27781 agaagaagta acaaactcgt catgacctct cctgcaaaga tattcccaaa aatccgcaaa
    27841 gccaaagata agaagtttgt aaattcttcc aagatattca tcggtatgac aaaaacagga
    27901 ctcataaaag attttatact ttttttaaat ccacgacgac gaacgctttc tatatgtgtc
    27961 aacaaaatga caagaaaaga taaggttaag tcatactgta aattagcggt tggcgaactc
    28021 caccagttag tcccatcgat cgtttgaatc tttgtcatta agccaaggtt attggcaatc
    28081 accatgaaaa ggaataaaca aaggaaaaag agtgagtaat ctttcatgta gcgcgaacca
    28141 atgttaggtt ctgtaaatcc aataacaaag tcatagacat actcaagtac attttgcttt
    28201 cctttgggtt tcaaggtcat attgcggctt gcccaataaa taaagacaaa aataactccc
    28261 acaatcaaca aagtcatggc taacatagtc agattgaaga taacaggacc aatagagatg
    28321 attggattaa tactttcttc catctaaaat cctccctttt cttctcgttc catgtattta
    28381 tttgataata aatgagaaga caagagttac aaagaaagtt ccttcaataa aggcaacacc
    28441 taaaaacatc aaactacgaa actcagaaag catatctggt tggcgtgcta ctgatttaaa
    28501 cagtccattc atcaataaac cttcaccgac agatacgccc atacaggcaa tacataagcc
    28561 taaaaatgtt aaattcataa caaattctcc tttaaaataa aatttactta cttagtgtag
    28621 tcctaaaatt taaatttgtc aacttttaac cgctattgga agcgtttaat aaaaattatt
    28681 tccattttgc taaatttcaa gttcaagtta gccatccaga agtcttctct gggtgacttg
    28741 tagtccaagc attttttagg atagttgtta atccactttt cgatgaatgc gacttctttg
    28801 ggagtcattt tcttggttcc cttaggtaac catctacgaa tgagcctgtt gtgattctca
    28861 ttagttcccc tttcccaaga ggcataggga tgtgcataat aaatgtgctc ctcagaaaat
    28921 acattagaca agcgattgaa ttccgttcca ttatctgccg tgatggaaag aatcttgtgt
    28981 tgttttaaga tgagttttag agcctgattg accacctcag cacttttatt tggaatcaat
    29041 cggatgatct gatgtctact ttttcgatcc gtcaagacaa gcaagcagta gtttttcgct
    29101 ctcgtaagta gaaccgtatc aatctcataa tgcccattct ccaagcgaaa attgatagct
    29161 tcaggccgct gttcgatgga ttgaccagca ggtttaaagt tggtgctggc ctgtttctta
    29221 agcgcttttc cttttctagg gtaaagcaga tcctgcttgc tttaccccaa ttttccatga
    29281 tgaatccaat agtaaatggt tgaaattccc acgttaaccc ctttagccat aaccatcatt
    29341 tcaggcaaaa atttttggtt atgatagtgg agaatctttt cctttagttc cttggtcacg
    29401 cttgatctct tgaccgagtg cttgcgatta ttttcataag actgttgagc atagtcggca
    29461 gaataaacct ctttgaagcg cccttttcca agacattttc ggactgtcct acgcttgatt
    29521 ttagtgtgga tagtttgagg agcttttcca agtagagagg caatttctct atttgatttt
    29581 ccttcttttt tccatctttc gattaagcga cggctatcga ttgtcaaatg tttacctttt
    29641 gtagtataat tgtcttgcat ttctgtgcct ttcttgtgtt tgtggttgaa caacaagtat
    29701 aacacagagg tgttttctta tgcctacaag agctttcatt atttccattt tcttttggat
    29761 ttcactctat tctgaaaaac ttgtgtatat ttactgaagc tagcaagtct tacctgtaaa
    29821 tttaatgaaa gcaacacaaa atccgagagg ggaatctcgg attaatagat agagagtttt
    29881 tagtttaaat aaattgttta aaatatcaac aacatcactt cttttcttaa cctgataagt
    29941 cttgattcct aattttgggg ctacgattat attgtcctca atatcgtcta gaaagacaca
    30001 atttctaggt tataactggt atttatcaat agttactcat atacatcagt ccacctccat
    30061 acttatgtgc gagcctctct ttgtattata cctccatact caccttacag attcttttgg
    30121 taataatatc tttgcctaat gtagagatag tcttgcaaag aaaaaacttc cttgtagcca
    30181 tgtttctgat aaaagtccgg tgcctggaac tggtaagtat tgacaaaggc aaaacaacaa
    30241 tttcgattct tagcttcact ttctgcctgt tgcaatagtt ttgaaccgat tccttgccct
    30301 cgcagttcct cttttacaaa caaatactcg atttctagcc aatttccaaa agtctctgct
    30361 atcaaacctg ccaggagatt gcccttttca tcttcgacat aaagattaag tggctcactt
    30421 tcagcctctt ctctttttga acggttataa acacgaatca gattccctat ttcttgcgat
    30481 ttatgtgatt ccttattttc caatctaaag tatagtgaaa tgaaataaaa catgcgcaaa
    30541 tcgattaagg aatttaatct aatttctaac aatgtcttag aaatcaaagt gtactat
//
LOCUS       DAVEHY010000026        30231 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVEHY010000026 DAVEHY010000000
VERSION     DAVEHY010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.026"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(1..124)
                     /locus_tag="VUZ44_001431"
                     /pseudo
     CDS             complement(1..124)
                     /locus_tag="VUZ44_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            242..2224
                     /locus_tag="VUZ44_001432"
     CDS             242..2224
                     /locus_tag="VUZ44_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0320332.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2525..7828
                     /locus_tag="VUZ44_001433"
     CDS             2525..7828
                     /locus_tag="VUZ44_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU0320333.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPLYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALILASVSLALSALFVVKTKKD"
     gene            complement(7995..10154)
                     /locus_tag="VUZ44_001434"
     CDS             complement(7995..10154)
                     /locus_tag="VUZ44_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU0320334.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10151..10747)
                     /gene="recU"
                     /locus_tag="VUZ44_001435"
     CDS             complement(10151..10747)
                     /gene="recU"
                     /locus_tag="VUZ44_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU0320335.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10813..11340
                     /locus_tag="VUZ44_001436"
     CDS             10813..11340
                     /locus_tag="VUZ44_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU0320336.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11410..11739
                     /gene="gpsB"
                     /locus_tag="VUZ44_001437"
     CDS             11410..11739
                     /gene="gpsB"
                     /locus_tag="VUZ44_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU0320337.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11760..12140
                     /gene="rnpB"
                     /locus_tag="VUZ44_001438"
     ncRNA           11760..12140
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VUZ44_001438"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12225..13382
                     /locus_tag="VUZ44_001439"
     CDS             12225..13382
                     /locus_tag="VUZ44_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU0320338.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALNWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13394..14788
                     /gene="mapZ"
                     /locus_tag="VUZ44_001440"
     CDS             13394..14788
                     /gene="mapZ"
                     /locus_tag="VUZ44_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU0320339.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14864..16288
                     /gene="gndA"
                     /locus_tag="VUZ44_001441"
     CDS             14864..16288
                     /gene="gndA"
                     /locus_tag="VUZ44_001441"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU0320340.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16300..16989
                     /locus_tag="VUZ44_001442"
     CDS             16300..16989
                     /locus_tag="VUZ44_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320341.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17087..18106
                     /gene="cbpC"
                     /locus_tag="VUZ44_001443"
     CDS             17087..18106
                     /gene="cbpC"
                     /locus_tag="VUZ44_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU0320342.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIHGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNLLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18224..19456)
                     /locus_tag="VUZ44_001444"
     CDS             complement(18224..19456)
                     /locus_tag="VUZ44_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU0320343.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19986..20461)
                     /locus_tag="VUZ44_001445"
                     /pseudo
     CDS             complement(19986..20461)
                     /locus_tag="VUZ44_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            20986..21315
                     /locus_tag="VUZ44_001446"
     CDS             20986..21315
                     /locus_tag="VUZ44_001446"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320344.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFCKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFHRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVR"
     gene            21437..22315
                     /gene="mvk"
                     /locus_tag="VUZ44_001447"
     CDS             21437..22315
                     /gene="mvk"
                     /locus_tag="VUZ44_001447"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU0320345.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            22297..23250
                     /gene="mvaD"
                     /locus_tag="VUZ44_001448"
     CDS             22297..23250
                     /gene="mvaD"
                     /locus_tag="VUZ44_001448"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU0320346.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            23237..24244
                     /locus_tag="VUZ44_001449"
     CDS             23237..24244
                     /locus_tag="VUZ44_001449"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU0320347.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            24228..25238
                     /locus_tag="VUZ44_001450"
     CDS             24228..25238
                     /locus_tag="VUZ44_001450"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU0320348.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            25315..26013
                     /locus_tag="VUZ44_001451"
     CDS             25315..26013
                     /locus_tag="VUZ44_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU0320349.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            26010..27005
                     /locus_tag="VUZ44_001452"
     CDS             26010..27005
                     /locus_tag="VUZ44_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU0320350.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            27019..27651
                     /locus_tag="VUZ44_001453"
     CDS             27019..27651
                     /locus_tag="VUZ44_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320351.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            27652..27893
                     /locus_tag="VUZ44_001454"
                     /pseudo
     CDS             27652..27893
                     /locus_tag="VUZ44_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            27818..28129
                     /locus_tag="VUZ44_001455"
     CDS             27818..28129
                     /locus_tag="VUZ44_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU0320352.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            28154..28420
                     /locus_tag="VUZ44_001456"
                     /pseudo
     CDS             28154..28420
                     /locus_tag="VUZ44_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            28570..28809
                     /locus_tag="VUZ44_001457"
     CDS             28570..28809
                     /locus_tag="VUZ44_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320353.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            28854..29483
                     /locus_tag="VUZ44_001458"
     CDS             28854..29483
                     /locus_tag="VUZ44_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU0320354.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            29782..30174
                     /locus_tag="VUZ44_001459"
     CDS             29782..30174
                     /locus_tag="VUZ44_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU0320355.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
BASE COUNT         9310 a         5394 c         6817 g         8710 t
ORIGIN      
        1 gatcttttgc tttagttcct tggtcaaggt tgattatttt cacggagcgc ttccgattgt
       61 tttcataaac catttgcgca tagtcagcag aataaatctt tttgaaacgt ccctttccta
      121 gacattatag aactttcaga ttcatctgaa tttaccaaat taacacaaaa attctgaaaa
      181 ttctgttgac atctttctga aaagagttta taatggagag aaagttttaa aggagaaaat
      241 gatgaaaagt tcaaaactat ttgcccttgc gggcgtgaca ttattggcgg cgactacttt
      301 agctgcatgc tctggatcag gttcaagcac taaaggtgag aagacattct catacattta
      361 tgagacagac cctgataacc tcaactattt gacaactgct aaggctgcta cagcaaatat
      421 taccagtaac gtggttgatg gtttgctaga aaatgatcgc tacgggaact ttgtgccgtc
      481 tatggctgag gattggtctg tatccaagga tggattgact tacacttata ctatccgtaa
      541 ggatgcaaaa tggtatactt ctgaaggtga agaatacgcg gcagtcaaag ctcaagactt
      601 tgtaacagga ctaaaatatg ctgctgataa aaaatcagat gctctttacc ttgttcaaga
      661 atcaatcaaa gggttggatg cctatgtaaa aggggaaatc aaagatttct cacaagtagg
      721 aattaaggct ttggatgatc agacagttca gtacactttg aacaaaccag aaagcttctg
      781 gaattctaag acaaccatgg gtgtgcttgc gccagttaat gaagagtttt tgaactcaaa
      841 aggggatgat tttgccaaag cgacggatcc aagtagtctc ttgtataacg gtccttattt
      901 gttgaaatcc attgtgacaa aatcctctgt tgaatttgcg aaaaatccga actactggga
      961 taaggacaat gtgcatgttg acaaagttaa attgtcattc tgggatggtc aagataccag
     1021 caaacctgca gaaaacttta aagatggtag ccttacagca gctcgtctct atccaacaag
     1081 tgcaagtttc gcagagcttg agaagagtat gaaggacaat attgtctata ctcaacaaga
     1141 ctctattacg tatctagttg gtacaaatat tgaccgtcag tcctataaat acacatctaa
     1201 gaccagcgac gaacaaaagg catcgactaa aaaggctctc ttaaacaagg atttccgtca
     1261 ggctattgca tttggatttg accgtacagc ctatgcctct cagttgaatg gacaaactgg
     1321 agcaagcaaa atcttacgta atatctttgt tccaccaaca tttgttcaag cagatggtaa
     1381 aaactttggc gatatggtca aagagaaatt ggttacttat ggggatgaat ggaaggatgt
     1441 taatcttgca gattctcagg atggtcttta caatccagaa aaagccaagg ctgaatttgc
     1501 taaagctaaa tcagccttac aagcagaagg tgtgactttc ccaattcatt tggatatgcc
     1561 agttgaccag acagcaacta caaaagttca gcgcgtccaa tctatgaaac aatccttgga
     1621 agcaacttta ggagctgata atgtcattat tgatatccaa caactacaaa aagacgaagt
     1681 aaacaatatt acatattttg ctgaaaatgc tgctggcgaa gactgggatt tatcagataa
     1741 tgtcggttgg ggtccagact ttgccgatcc atcaacctac cttgatatca tcaaaccatc
     1801 tgtaggagaa agtactaaaa catatttagg gtttgactca ggggaagata atgtagctgc
     1861 taaaaaagta ggtctatatg actacgaaaa attggttact gaggctggtg atgaggctac
     1921 agatgttgct aaacgctatg ataaatacgc tgcagcccaa gcttggttga cagatagtgc
     1981 tttgattatt ccaactacat ctcgtacagg gcgtccaatc ttgtctaaga tggtaccatt
     2041 tacaatacca tttgcattgt caggaaataa aggtacaagt gaaccaatct tatataaata
     2101 cttggaactt caagacaagg cagtcactgt agatgaatac caaaaagctc aggaaaaatg
     2161 gatgaaagaa aaagaagagt ctaataaaaa ggctcaagaa gatctcgcaa aacatgtgaa
     2221 ataactgttg caaaatataa gaaaggattt agtatttctc ttgaatgctg aatccttttt
     2281 tacatttgta aagaaagatt ctaaatgtac tgacccccaa aagttggagc ctctttttgt
     2341 cagaatagag aaaatttttg ttaattttac ttgtttccta ttgctttctc agctattatt
     2401 tgttatatta aaagtataat tattttttat ttatcagggt taagcattgc actttcagag
     2461 gaaggagtat tttttaaaaa gaaaatgtaa acgcttgcta aaaaatgaaa ggatttagaa
     2521 gtttatgaat aaaggattat ttgaaaaacg ttgtaaatat agtattcgga aattttcatt
     2581 aggtgttgct tctgttatga ttggagctgc attctttggg acaagtccgg ttcttgcaga
     2641 tagcgtgcag tctggttcca cggcgaactt accagctgat ttagctactg ctcttgcaac
     2701 agcaaaagag aatgatggac gtgattttga agcgcctaag gtgggagaag accaaggttc
     2761 tccagaagtt acagatggac ctaagacaga agaagaacta ttagcacttg aaaaagaaaa
     2821 accagctgaa gaaaaaccaa aagaggataa acctgcagct gctaaacctg aaacacctaa
     2881 gacggtaacc cctgaatggc aaacggtaga gaaaaaagaa caaaagggaa cagtcactat
     2941 ccgagaagaa aaaggtgtcc gctacaacca actatcctca actgctcaaa atgataacgc
     3001 aggtaaacca gccctgtttg aaaagaaggg cttgaccgtt gatgccaatg gaaatgcaac
     3061 tgttgattta accttcaaag aagattctga aaagggcaaa tcacgctttg gtgtcttctt
     3121 gaaatttaaa gataccaata ataatgtttt tgtcggttat gacaaggatg gctggttctg
     3181 ggaatacaaa actccaggta atagcacatg gtataaaggc aaccgtgtag ttgcaccaga
     3241 accgggttct gtaaaccgtc tttctatcac tctcaagtca gatggacaac tcaatgccag
     3301 caataacgat gtcaatctct ttgacacagt gacactgcct ggggcggtca atgataatct
     3361 taaaaatgag aagaagatcc ttctcaaggc aggaacttat ggcaatgacc gtacggttgt
     3421 cagcgttaaa acggataatc aagaaggcgt aaaagcggat gatactcctg cccagaaaga
     3481 aacaggtccg gttgttgacg atagcaaggt gacttatgat acgatccagt ctaaggtact
     3541 taaggcagta attgaccaag ccttccctcg tgtcaaggaa tacaccttga atggacatac
     3601 tttgccagga caggtgcaac agttcaacca agtctttatc aataaccacc gaatcacccc
     3661 tgaagtcact tataagaaaa tcaatgagac aacagcagag tacttgatga agcttcgcga
     3721 tgatgctcac ttaatcaatg cggaaatgac agtacgcctg caagttgtgg acaatcaatt
     3781 gcactttgat gtgaccaaga ttgtcaacca caatcaagtc actccaggtc aaaagattga
     3841 tgacgaaaga aaactacttt cttctattag tttcctcggc aatgctttag tctctgtttc
     3901 tagtgatcaa actggtgcta agtttgatgg ggcaaccatg tcaaacaata cgcatgtcag
     3961 cggagatgat catatcgatg taaccaatcc aatgaaagac ctagccaagg gttacatgta
     4021 tggatttgtt tctacagata agcttgctgc tggtgtttgg agtaactctc aaaatagcta
     4081 tggtggtggt tcgaatgact ggactcgttt gacagcttat aaagaaacag tcggaaatgc
     4141 caactatgta ggaatccata gctctgaatg gcaatgggaa aaagcttata agggcattgt
     4201 tttcccagaa tacacgaagg aacttccaag tgctaaggtt gttatcactg aagatgccaa
     4261 tgcagacaag aaagttgatt ggcaagatgg tgccattgct tatcgtagca ttatgaacaa
     4321 tcctcaaggt tgggaaaaag ttaaggatat cacagcttac cgtatcgcga tgaactttgg
     4381 ttctcaagca caaaacccat tccttatgac cttggatggt atcaagaaaa tcaatctcca
     4441 tacagatggt cttgggcaag gtgttctcct taaaggatat ggtagcgaag gccatgactc
     4501 tggtcacttg aactatgctg atattggtaa gcgtatcggt ggtgtcgaag acttcaagac
     4561 cctaattgag aaggctaaga aatatggagc tcatctaggt atccacgtta acgcttcaga
     4621 aacttatcct gagtctaaat acttcaatga aaaaattctc cgtaagaatc cagatggaag
     4681 ctatagctat ggttggaact ggctagatca aggtatcaac attgatgctg cctatgacct
     4741 agctcatggt cgtttggcac gttgggaaga tttgaagaaa aaacttggtg acggtctcga
     4801 ctttatctat gtggacgttt ggggtaatgg tcaatcaggt gataacggtg cctgggctac
     4861 ccacgttctt gctaaagaaa ttaacaaaca aggctggcgc tttgcgatcg agtggggcca
     4921 tggtggtgag tacgactcta ccttccatca ctgggcagct gacttgacct acggtggcta
     4981 caccaataaa ggtatcaaca gtgccatcac ccgctttatc cgtaaccacc aaaaagatgc
     5041 ttgggttggg gactacagaa gttatggtgg tgcagccaac tatccactgc taggtggcta
     5101 cagcatgaaa gactttgaag gctggcaagg aagaagtgac tacaatggct atgtaactaa
     5161 cctctttgcc catgacgtca tgactaagta cttccaacac ttcactgtaa gtaaatggga
     5221 aaatggtaca ccggtgacta tgaccgataa cggtagcacc tataaatgga ctccagaaat
     5281 gcgagtggaa ttggtagatg ctgacaataa taaagtagtt gtaactcgta agtcaaatga
     5341 tgtcaatagc ccactatacc gtgaacgtac agtaacgctc aacggacgtg tcatccaaga
     5401 tggttcagct tacttgactc cttggaactg ggatgcaaat ggtaagaaac tttctactga
     5461 taaggaaaag atgtactact tcaatacgca ggccggtgca acaacttgga cccttccaag
     5521 cgattgggca aagagcaagg tttaccttta caagctaact gaccaaggta agacagaaga
     5581 gcaagaacta actgtaaaag atggtaaaat taccctagat cttctagcaa atcaaccata
     5641 cgttctctat cgttcgaaac aaaccaatcc tgaaatgtca tggagtgaag gcatgcacat
     5701 ctatgaccaa ggatttaata gcggtacctt gaaacattgg accatttcag gcgatgcttc
     5761 taaggcagaa attgtcaagt ctcaaggggc aaacgatatg cttcgtattc aaggaaacaa
     5821 agaaaaagtt agtctcaccc agaaattaac tggcttgaaa ccaaatacca agtatgccgt
     5881 ttatgttggt gtagataacc gtagtaatgc caaggcaagt atcactgtga atactggtga
     5941 aaaagaagtg actacttata ccaataagtc tctcgccctc aactatgtaa aagcctacgc
     6001 ccacaataca cgtcgtaaca atgctacagt tgacgataca agttacttcc aaaacatgta
     6061 cgccttcttt acaactggat cggacgtatc aaatgttact ctgacattga gtcgtgaagc
     6121 tggtgatcaa gcaacttact ttgatgaaat tcgtaccttt gaaaacaatt caagcatgta
     6181 cggagacaag catgatacag gtaaaggcac cttcaagcaa gactttgaaa atgttgctca
     6241 gggtatcttc ccatttgtag tgggtggtgt cgaaggtgtt gaagataacc gcactcactt
     6301 gtctgaaaaa cacaatccat atacacaacg tggttggaat ggtaagaaag tcgatgatgt
     6361 tatcgaagga aattggtcac tcaagacaaa tggactagtg agccgtcgta acttggttta
     6421 ccaaaccatc ccacaaaact tccgttttga agcaggtaag acctaccgtg taacctttga
     6481 atacgaagca ggatcagaca atacctatgc ttttgtagtc ggtaagggag aattccagtc
     6541 aggtcgtcgt ggtactcaag caagcaactt ggaaatgcat gaattgccaa atacttggac
     6601 agattctaag aaagccaaga aggcaacctt ccttgtgaca ggtgcagaaa caggcgatac
     6661 ttgggtaggt atctactcaa ctggaaatgc aagtaatact cgtggtgatt ctggtggaaa
     6721 tgccaacttc cgtggttata acgacttcat gatggataat cttcaaatcg aagaaattac
     6781 cctaacaggt aagatgttga cagaaaatgc tctgaagaac tacttgccaa cggttgccat
     6841 gactaactac accaaagagt ctatggatgc tttgaaagag gcggtcttta acctcagtca
     6901 ggccgatgat gatatcagtg tggaagaagc gcgtgcagag attgccaaga ttgaagcttt
     6961 gaagaatgct ttggttcaga agaaaacggc tttggtagca gatgactttg caagtcttac
     7021 agctcctgct caggctcaag aaggtcttgc aaatgccttt gatggcaatg tgtctagtct
     7081 atggcataca tcttggaatg gtggagatgt aggcaagcct gcaactatgg tcttgaaaga
     7141 accaactgaa atcacaggac ttcgctatgt tccgcgtgga tcaggttcaa atggtaactt
     7201 gcgagatgtg aaacttgttg tgacagatga gtctggcaag gagcatacct ttactgcaac
     7261 tgattggcca gataacaata agccaaaaga cattgatttt ggtaagacaa ttaaggctaa
     7321 gaaaattgtc cttactggta ccaagacata cggagatggt ggagataaat accaatctgc
     7381 agcggaactt atctttactc gtccacaggt agcagaaaca cctcttgact tgtcaggcta
     7441 tgaagcagct ttggttaagg ctcagaaatt aacagacaaa gacaatcaag aggaagtagc
     7501 tagcgttcag gcaagcatga aatatgcgac ggataaccat ctcttgacgg aaagaatggt
     7561 ggaatacttt gcagattatc tcaaccaatt aaaagattct gctacgaaac cagatgctcc
     7621 aactgtagag aaacctgagt ttaaacttag atctttagct tccgagcaag ggaagacgcc
     7681 agattataag caagaaatag ctagaccaga aacacctgaa caaatcttgc cagcaacagg
     7741 tgagagtcaa tctgacacag ccctcatcct agcaagtgtt agtctagccc tatctgctct
     7801 ctttgtagta aaaacgaaga aagactagta tttagtaaaa cctcttaaca agattacgga
     7861 agcagtctct atcttttcca atgaggttta tagtacagaa aaagcctgag aagatgtctt
     7921 ctcaggcttt tgttaagcac ataaatacaa tagtgctatg acaaaatcac ccagaaaaat
     7981 ctgggtgata aatgttatgg ttgtgctggt tgaggattct gattttgttg atcaggggtt
     8041 gtatttgatt gttgcgtatt attgttagga ttggtagtcg tactattatt tgtgcttgga
     8101 gtggttgagc tagactgtga agttgaacta tctgatgatg agcttgaact ttcagttgat
     8161 gggggttgtt gtggagcagg tgagctccac gtagaacgag caccattttt aaatacgaat
     8221 tctccatttc tgtagagccc ctctggtata ttccaatcct ctggattgct tccttcagac
     8281 aggtaggtca tcatagagcg gtaaactttg gcagcgaccg taaggccatt gcctacaagt
     8341 ggtgtcagac ggttagaata gcctgtccat acagccattg aatatttacg cgtatagcca
     8401 gcaaatagtt catcaggtgc tacaaattga gaggtcttga tgtggttttc aatttcctcg
     8461 tctgtatagt tagaggttcc tgttttacca gcctgaggga gccaagcaag ataggcattt
     8521 cgtccagttc cataactcaa gactgttttc atcatgtcgg tcatcatata ggctgtcgtt
     8581 tccttcatgg cacgagttcc gacattagag aactcttttt cactcccatc actaaagacg
     8641 actttatgga tatacattgg tttatagtaa gttccaccat ttgcaaaggc agcgtaagca
     8701 gcagccatct tttcactact tgctccatat tttttgtctg attcggttgt gttacttgaa
     8761 atggcatttg agtagtgaat acttgggtag tcgattccga gaccatttag gaaagtcttg
     8821 gcgcggttga gtccgacctt gtttagagtt tccacggctg ggacgtttcg cgattgttgc
     8881 agggcgtatt gcaaggtgat gttgccaaag tagcccctat cccagttata aacaggggta
     8941 tttgtcccag ggtagttata gggttcatcg tgaacgatag tagcagttga atcgtagaca
     9001 ccgtactcca aggcaggagc atagtctgtg atcggtttca tagttgatcc ccagtcgcgg
     9061 tttgtttcta ctgcttggtt aattccgaag gaaacattgc ttgactgatg gcgtgctcct
     9121 agctgggcaa tgactttacc gttagaaaca tcaacaatgg tagaagcgac ttgcaattca
     9181 tcgtctggat aggcaacgta ttcgtctgta ttgtaaatat cccacagatg tttttgagct
     9241 tcttggtcta catttgtgta gacatccatc ccagttgtga gcaggttata gcctgtttct
     9301 tcttcaactt gattgatgac ttccttgagg taattatcca tgtaagcagg gtaattactt
     9361 gctgatttga gactttgtag tccatcagta attggtgtat tgactgcttt ctcatactgt
     9421 tcagcagaga tgtagccttg atttttcatt tcagataaga ccaagtttcg gcggtcttgg
     9481 gctgcttctg gatgtgaata ggggtcatat tggtttggtg cctgaggcat tccagccagc
     9541 aaggctaact gaggtaaact taaattattg aggtctttac catagtagtt ttgagctgct
     9601 gtctgcattc catagttccc attagacatg tagaccttat ttatatagta ggtcaagatt
     9661 tcttgcttgg ttgctttttg ttctaactga atcgctaacc aagcttcctg agccttacga
     9721 gaaatagtct ggtcggaagt cgaagttgaa aagtaagtca acttaatcaa ctgttgagtg
     9781 agagttgatc caccttggag ggaattgctt tgcagattgc gcaagaaagc tcccaggata
     9841 cggatggtat caatccccct gtggtcgaag aagcgatggt cttcgataga aacgattgct
     9901 ttaaccaaat ctgtgggaat atcattagct tgggcattga cgcggcgttc agaacccaag
     9961 tcagcaatga gttgattttt attgtcgtag attttactag aagttgttgc aactagttta
    10021 ctctcggata ggctaggagc cttgctaacg tagtagaaaa aaactcctcc gcctaagaca
    10081 atggctgcga taaccaagct taagaagcta atgctcagat acttgattag gcgcagaatc
    10141 gttggtttgt tcatcttgtt ttaccaccta ataaatgttc tttgataaca ttgagataag
    10201 gaatttgagg gaaggcacca gccttgattt catatccata ttctcgaata tattcaagtg
    10261 gcattgattt ttgtccctta tcttgatgat agaagcgaat caaatcgaat gccggcaata
    10321 agtaggtttc ttgctgagaa gaaaagtgaa gaaggacaaa gcagattcct tgttgggcaa
    10381 ggacttgttc catatgctga atctgatgtg gatgaaaatt tttcatcgga atcgcacgtt
    10441 tttgttttgt ttccttgact tcaaagtcga tgtaatatcc attataaacg ccagaatagt
    10501 ccgtcgttga agcttgtcga aaataggctt caacaatctt ggcacgactt cgttgtggat
    10561 agtccacttg tacgatttga ataggagttg gtttcttatg tataacagcc aagccctgag
    10621 acaaatagta gtcgttggta gcattgatca tcttttcaaa agacattcct cgatttgcga
    10681 aatttttggg ttgagaaaga gatgtttgtc ttttttgtga tgaaacttta tgtggatagt
    10741 tgaccataat tctccttatt ggtacaataa catcacttta ttataccata atttgcacag
    10801 aaagggttaa aaatggctac agctttggtt ttaggctatt ctgcttttga tttgggttta
    10861 ttttctgata aggatcctcg tcttaaattg attaaaaaag cgatacgtaa agatttagag
    10921 gctatggcag cagatggggt gtcttggctt gtgtttacag ggagtttggg ttttgaatat
    10981 tgggttttag aggttgctca ggagatgaaa accgaatacg gtttccagtt ggccaccatt
    11041 tttgcttttg aaacccatgg ggaaaattgg aatgaaggca atcagatgaa actgagtcgc
    11101 tttaagcagg tagactttgt caaatatgct tatcctcgct atgaacacaa ggggcagtta
    11161 agagattacc agcagttttt gctggaaaac acgactagtt cctatctttt ttatgatgaa
    11221 gaaaatgaaa caaaactagc ttatttttac caaaagatga aaaatcaaga ggactatttt
    11281 ataaagagat taacatttga tcaattaaat gaacttgctg aaaatttttc cgaaaattga
    11341 agctttgacc ttgatttttg tttgcctttt tttatataat aatactagca agcgagaatg
    11401 gagagagaca tggcaagtat tattttttca gcgaaagata tttttgaaca agagtttgga
    11461 cgtgaagtcc gtggctataa taaagtagaa gttgacgagt ttttagacga tgtcatcaag
    11521 gactatgaaa cctatgctgc cttggtcaag tcacttcgtc aggaaattgc ggatttgaag
    11581 gaagaattaa ctcgtaaacc gaaaccttca ccagttcaag cagaacccct tgaagcggca
    11641 attacaagtt ctatgacgaa ttttgatatt ttgaaacgcc tgaatagatt ggaaaaagaa
    11701 gtttttggta aacaaatttt agataactca gatttttaag tagttatttg agatgtgcaa
    11761 tttttggata atcgcgtgag gagaattgct tctcatgagg aaagtccatg ctagcacagg
    11821 ctgtgatgcc tgtagtgttt gtgctaggcg aaaccataag cctagggacg agaaatcgtt
    11881 acggcagttg aaatggctaa gtccttggat aggccagagt aggcttgaaa gtgccacagt
    11941 gacggagtct ttctggaaac agagagagtg gaacgcggta aacccctcaa gctagcaacc
    12001 caaattttgg tcggggcatg gagtacgcgg aaacgaacgt agtattctga ctgctatcag
    12061 ctagagctgt tagtggtaga cagatgatta tcgaaggaag tggtcctagt cacttctgga
    12121 acaaaacatg gcttatagaa aattgcatat aggttggggc tgagaaattt tctcaacctc
    12181 attttttaaa gtggacatat agaaaggtct tgcaagactg taacatgaaa aaagaattta
    12241 atttaattgc aactgtggca gcagggcttg aggctgtcgt tggtcgtgaa gtgcgagagt
    12301 tgggctacga ttgtcagatt gaaaatggac gtgttcgttt tcaaggagac gtgagagcta
    12361 ttatcgaaac caacctttgg ctgcgggcag cagatcgtat caaaattatc gtaggaacgt
    12421 tccctgctaa gacttttgaa gagctatttc agggagtttt cgctttaaat tgggaaaatt
    12481 atttaccact tggagctcgg ttcccgattt caaaagctaa atgtgttaag tccaaacttc
    12541 acaatgagcc cagtgttcag gctatttcta agaaagctgt tgtcaagaaa ttgcagaaac
    12601 actatgctcg cccagaaggg gttcctctga tggagaatgg cccagagttt aagattgagg
    12661 tctctattct caaagatgtg gcaactgtca tgattgatac gaccgggtct agcctcttta
    12721 aacgtggtta tcgtaccgaa aaaggtggcg ctcctatcaa ggaaaatatg gcagcagcca
    12781 ttttacaact ttctaactgg tatccagaca agcctttgat tgatccgacc tgtggttcgg
    12841 ggactttctg tattgaggca gttatgattg ctagaaagat ggcgccaggt cttcgtcgct
    12901 cttttgcatt tgaggaatgg aactggatca gcgatcgctt gattcaagaa gtgcgcacag
    12961 aagcggctaa aaaagtagac cgtgagcttg agctggatat catgggctgt gatattgatg
    13021 ctcgcatggt ggaaattgct aaggccaatg ctcaggtagc tggtgttgca ggagacatta
    13081 cttttaagca gatgcgcgtg caggatttac gttccgataa aatcaatgga gtaatcattt
    13141 ccaatccgcc ttatggtgaa cgtttgtcag atgatgcagg ggtgaccaag ctctatgctg
    13201 agatggggca agtatttgca ccgctgaaaa cttggagcaa atttatcctg actagtgatg
    13261 aagcttttga aagcaagtat ggtagccaag cagataagaa gcgtaagtta tacaacggaa
    13321 ccttgaaagt ggatctatat caatattttg gtcagcgtgt caaacggcaa gaggtaaaat
    13381 agaaaggata ctcatgagta aaaaaagacg aaatcgtcaa aaaaaagaag gtcaagaacc
    13441 gcaatttgat tttgatgaag caaaagagct aacagttggt caagctattc gtaaaaatga
    13501 agaagtggaa gcaggagtct tgcctgagga ttccattttg gacaagtatg ttaagcaaca
    13561 cagagatgaa attgaggcgg ataagtttgc gactcgtcaa tacaaaaaag aggagttcgt
    13621 tgaaactcag agtctggatg atttaattca agagatgcgt gaggctgtag agaagtcaga
    13681 agcttcttcg gaggaagttc catcttctga agacatctta ctacccttgc ctctggacga
    13741 tgaggagcaa ggcttggatc ctctattgct agatgatgaa aatccaacag aaatgactga
    13801 agaagtggaa gaggagcaaa acctttctcg tctggatcaa gaggactcag aaaagaaaag
    13861 taaaaaaggc tttattttga ccgttttggc gcttgtatca gtaattattt gtgtcagtgc
    13921 ttattatgtc taccgtcaag tggctcgttc gaccaaggaa attgaaactt ctcaatcaac
    13981 tacagccaat caatcggatg tggatgattt taatacactt tatgacgcct tttacacaga
    14041 tagcaataaa acggctttga aaaatagcca gtttgataaa ctgaatcaac tcaagacttt
    14101 acttgataag ctggaaggta gtcgtgaaca tacgcttgcc aaatctaaat atgatagtct
    14161 agcaacgcaa atcaaggcta ttcaagatgt caatgcacaa tttgaaaaat cagctattgt
    14221 ggatggtgtg ttggatacca atgccaaagc caaatcggat gctaaattta cagatattaa
    14281 aactggaaat acggagcttg ataaagtgct agataaggct atcagtcttg gtaagagcca
    14341 gcaaacaagt acttctagct caagtttaag tcaaactagc agctcaagtt caagtcaagc
    14401 aagttcaaat acgactagtg agccaaaacc aagtagttca aatgagacta gaagtagtcg
    14461 cagtgaagtc aatatgggtc tctcgagtgc aggggttgct gttcaaagaa gtgccagtcg
    14521 tgttgcctat aatcagtctg ctattgatga tagtaataac tctgcctggg attttgcgga
    14581 tggtgtcttg gaacaaattc tagcgacttc acgttcacgt ggctatatca ctggagacca
    14641 atatatcctt gaacgtgtca atatcgttaa cggcaatggt tattacaacc tctataagcc
    14701 agatggaacc tatctcttta cccttaactg taagacaggc tactttgtcg gaaatggcgc
    14761 tggtcatgcg gatgacttgg actactaagc agtcgttaca aaattctttc ttttcaaaag
    14821 taaaaatgat aaaataaaac aaatgaaaca agaggagtgt caaatgacaa aagctaactt
    14881 tggtgtcgta ggtatggccg taatgggtcg taaccttgcc cttaatattg aatcacgtgg
    14941 ttacacagtt gctatctaca accgtagtaa agaaaaaacg gaagatgtga ttgcttgcca
    15001 tcctgaaaag aactttgtac caagctatga cgttgaaagt tttgtaaact caatcgaaaa
    15061 acctcgtcgt atcatgctga tggttcaagc tggacctggt acagatgcta ctatccaagc
    15121 ccttcttcca caccttgaca aaggtgatat cttgattgac ggtggaaata ctttctacaa
    15181 agataccatc cgtcgtaatg aagaattggc aaactcaggt atcaacttta tcggtactgg
    15241 agtttctggt ggtgaaaaag gtgctcttga aggtccttct atcatgcctg gtggacaaaa
    15301 agaggcctac gaattggttg cggatgttct tgaagaaatc tcagctaaag caccagaaga
    15361 tggcaaacca tgtgtgactt atatcggtcc tgatggagct ggtcactatg tgaaaatggt
    15421 tcacaacggt atcgagtacg gtgatatgca attgatcgca gaaagttatg acttgatgca
    15481 acacttgcta ggtctttctg cagaggatat ggctgaaatc tttactgagt ggaacaaggg
    15541 tgaattggat agctacttga tcgaaatcac agctgatatc ttgagccgta aagacgatga
    15601 aggccaagat ggaccaatcg tagactacat ccttgatgct gcaggtaaca agggaactgg
    15661 taaatggact agccaatcat ctcttgacct tggtgtacca ttgtcactga ttactgagtc
    15721 agtgtttgca cgctacattt caacttacaa agaagaacgt gtatatgcta gcaaggtgct
    15781 tccaaaacca gctgccttca actttgaagg agacaaggct gaattgattg aaaagatccg
    15841 tcaagccctt tacttctcaa aaatcatttc atacgcacaa ggatttgctc aattgcgtgt
    15901 agcctctaaa gaaaacaact ggaacttgcc atttgcagat atcgcatcta tctggcgtga
    15961 tggctgtatc atccgttctc gttttttgca aaagattaca gatgcttaca accgcgatgc
    16021 agatcttgcc aaccttcttt tggacgagta cttcttggat gttactgcta agtatcaaca
    16081 agcagtgcgt gatatcgtag ctcttgcggt tcaagctggt gtgccagtgc caactttctc
    16141 agcagctatt acttactttg atagctaccg ttcagctgac cttccggcta acttgatcca
    16201 agcacaacgt gactactttg gtgctcacac ttaccaacgt aaagacaaag aaggaacctt
    16261 ccactactct tggtatgacg aaaaataagt aggtcagcca tggggaaacg gattttatta
    16321 cttgagaaag aacgaaatct agctcatttt ttaagtttgg aactccagaa agagcagtat
    16381 cgggttgatc tggtagagga ggggcaaaaa gccctttcca tggctcttca gacagactat
    16441 gatttgattt tattgaacgt taatctggga gatatgatgg ctcaggattt tgcagaaaaa
    16501 ttgagtcgaa ctaaacctgc ctcagtcatc atgattttag atcattggga agacttgcaa
    16561 gaagagctgg aagttgttca gcgttttgca gtttcataca tctataagcc agtctttatc
    16621 gaaaatctgg tagcgcgtat ttcggcgatc ttccgaggtc gggacttcat tgatcaacac
    16681 tgcagtctga tgaaagttcc aaggacctac cgcaatctta ggatagatgt tgaacatcac
    16741 acggtttatc gtggtgaaga gatgattgct ctgacccgcc gtgagtatga ccttttggcg
    16801 acacttatgg gaagcaagaa agtattgact cgtgagcaat tgttggaaag tgtttggaag
    16861 tatgaaagtg cgaccgagac aaatatcgta gatgtctata tccgctatct acggagcaag
    16921 cttgatgtta aaggtcaaaa aagctacatt aaaaccgtgc gtggtgttgg ttacaccatg
    16981 caagaataga aaagcagttg cagttgtgta actgcttttt tgaggagttt ttatatattg
    17041 acatgcagtc gggtctttgc tacaatcagt tatggaggat atataaatga aacttttgaa
    17101 aaaaatgatg caagttctac tagcagtctt tttctttggt ttgctagcta caaatacggt
    17161 atttgcaaat accacaggtg gccgatttgt tgataaggat aatagaaaat attatgtaaa
    17221 agatgatcat aaagcaatct attggcataa aatagacggt aaaacttact attttggtga
    17281 tattggagag atggttgtcg gttggcaata cttagaaatt catggaacag gttatcgtga
    17341 taatttattc gataaccaac cagttaatga aattggcctt caggagaagt ggtactattt
    17401 tggacaagat ggtgctttgc tagaacaaac agataaacaa gtactagagg caaaaacgtc
    17461 tgaaaataca ggaaaagtat acggtgaaca atatcctcta tctgctgaaa agagaactta
    17521 ttattttgat aataattatg ctgtaaagac aggctggatt tatgaagacg gcaattggta
    17581 ttatttaaat aagctaggaa attttggcga tgattcttac aatctactac caattggtga
    17641 agttgctaag ggttggactc aagattttca tgttactatt gacattgata gaagcaaacc
    17701 tgctccatgg tactacctag acccagaaac tggcattatg cgaacaggat ggcaatatct
    17761 aggtaataac tggtactacc tccgttcatc aggagcaatg gccactggct ggtatcagga
    17821 aggtaccact tggtattatt tagaccagcc aaatggcgat atgaaaacag gttggcaaaa
    17881 ccttgggaac aaatggtact atctccgttc atcaggagct atggcaactg gttggtatca
    17941 agatggttca acttggtact acctaaatgc aggtaatgga gacatgaaga caggttggtt
    18001 ccaggtcaat ggcaactggt actatgctta tagctcaggt gctttggcag tgaatacgac
    18061 cgtagatggc tattctgtca actataatgg cgaatgggtt cggtaatgac agggcgctta
    18121 taattatatt agaacactcg cttaatcaaa gaagtgactt tgttgtactt gacctgacga
    18181 ttggggagat taaaagcatg tgaaatctac acatgctttt tcgttagtta tgagtgttga
    18241 acttgactaa ccattgacaa aagataagag caattaaaat aagatacaaa aatatcaatg
    18301 ctaactgcac cgaaacgccc gatgctatgg atagggctaa tagggagagc agggacgggg
    18361 cgagaatgtc cactgtgctc agagcagagc ccaccgtccc catcttgtca ctggggatat
    18421 aggcaaagac agctgcttgt aggcgagggc tgagaatgcc gataatcgta gaactgatga
    18481 aactggtcat gaaaattacg atataggctt gacaaaggat actagttatt agagccaata
    18541 gggaaatctc acagaaaacc aagaggtgcg tgaaacggat atttttaaat agattactgc
    18601 tggtcatatt gccaaggata gctccacaag acatgatgat ggagagcagg gcgaggagtt
    18661 gcccaatgct cagttgtgct agtgtctgtt ggatgaagcg gagggcaatc agccgagggg
    18721 acacatccaa gatggcaatc atactggtcg tcagaaacag tagtatgacg gtatctttta
    18781 acttcagtag cacagccagc gactgtttaa gatgttgaaa atatttctta aaactcagtg
    18841 ctgtatgtga catttcaatc cttttttcaa cctcatacaa ggtatgtcga ataacataca
    18901 ggcccaaaaa ggcaatgaca aaagtcagag tgttgataag ggaaatagtt tgaatactta
    18961 taacattgat aaggaatgcg ccagccagat tggcgacaat gcggacaacc ctcatcagag
    19021 actgcctgaa ccccatggca tcatgcaggt cgtccttaat tacactgatg tagagggcgt
    19081 tcatcatgta ggcagacagg tagctcaagg tgtcagagat gaggttgatg atgacaatca
    19141 taatgactga aactaatgaa aagggcgaca agacgagaaa tactgtcaaa atagcgtaga
    19201 gcaggatttt gattttggca atacagagtg cgtgtttgac tctattttct tgaaaatctc
    19261 ctagaatccc gagaaagagt tgcgatagta ggggaaccat ctctgaaatg gaaatcagta
    19321 aaatcgctag cggagcgaaa ttgtactgag ccacataatt gataatggcg aggtagaaaa
    19381 tactgtcgcc gaatgatgaa aaacagctgt ttagcagcaa ctgtctatat atgttgtttg
    19441 tccaaaataa tttcatacat ttctccttat gtctgcacat cgaatgggaa tttattattt
    19501 aatagacacc aatatacccc catgcttcct attccgaagt caaacaaatc tgctttacca
    19561 ctatctcctt gaaacatcag taaaccgtga tcatctcgtt cagaacatgc taaaattacc
    19621 tgttggattt tttcatcagt aatttgtttt gattgtagac agtggtttgt agtaagctag
    19681 ttattccgtg gcaatatcct gtcatcattt ttagatgatg gttaaaaaca aattcttgat
    19741 atttactaat aatatctttg tttccgtcac aatcgtacat acaaagatat aagattattc
    19801 cggaaattcc tttgcaccaa gaaagttgtg aatttcctaa attttcagta ttagaagtaa
    19861 ctttttctaa taattttttt aattcagtat ggaatgtatg gagatcatta tagaacatag
    19921 aaggttctaa gactttagaa taggcaaata aagcctatgc aattccacaa tatccatgag
    19981 caaagctata gtctaaaatg ctttctttgg ctatatctct ttgtaggaaa taatgctaaa
    20041 tttcccctat actattgtgg atgaaaattt taagagtatt gtcattggta aattgatagt
    20101 attttattaa tgataatagg acaccagatt ttcccaatgc aaagtctatt tcctctagag
    20161 tatcataatt ctctattaat ttcttagcgg agacgtttgc taattgtaga tagtattgat
    20221 ttttactgat agaaaataaa tgtaggagta accatagata gcctgcatca ccaaatagca
    20281 gtgagtattg atatttatat gtgtgtgtcg ttctaattgt cactgccttc ttgatgatag
    20341 agagtatttt agaatccagt tctggggggt acaatttatt tagaggaaac agtagtccag
    20401 ctattccgtg ttggaatgat aaattactta cgaaatttcc aaattctgtt gaagaagtga
    20461 tccttccttc agaatttaca gttttatcta gtaaaaatcg tagaacacta ttacattctg
    20521 ttttgtaatc atatttatgt tcctctattt ttttaatttt gactaaatta tttgtttgac
    20581 ttaaatttag tagacattgt aaccaaaata gttgctcatc tgtgagctga ccttgagtat
    20641 gtgatagttc tagtaattga ataggatcct ttagttagat tcaatcaatc tataacacaa
    20701 caacataata atacttttag gataacttgt caaatattat agtaaaatga aataataaca
    20761 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta
    20821 ctattctagt ttcaatctaa tatagtatat atttttacat attgagttgt caaattaagt
    20881 gcataagttt cccgtagcat acttcataag gcgttttcca cttaagaaat tttcgtggtc
    20941 gattatttag aacctgtatt cacaaaaaaa tgttaaacta gagttatgac acgcaaagca
    21001 tatgatactg atttaaacga tcaagaatgg gcgaagattg aaccctattt ctgcaaacac
    21061 cgcacctata aatggccgaa acgagtactt gttaatgaaa ctttgtacgt cactaaaaca
    21121 ggttgtcaat ggcgcatgct ccctcatgac tttcctcttt acttaatggt atggagtttc
    21181 tttcatcgtt ctatgacgac aggttggttc caggtcaatg gcagatggta ctacgcttat
    21241 agctcaggtg ccttggcagt gaatacgact gtagatggct attctgtcaa ttataatggt
    21301 gaatgggttc ggtaatgaaa gaagcgattg tgaatggaaa caatcgcttt ttttgtgaaa
    21361 atataataaa atagatagga aagaattaat acttgtatga aaaataagac gttttttcgt
    21421 ctagtaaaag gaaaaaatga caaaaaaagt tggtgtcggt caggcacata gtaagataat
    21481 tttaataggg gaacatgcgg tcgtttacgg ttatcctgcc atttccctgc ctcttttgga
    21541 ggtggaggtg acctgtaagg tagttcctgc agagagtcct tggcgccttt atgaggagga
    21601 taccttgtcc atggcggttt atgcctcact ggagtatttg gatatcacag aagcctgcat
    21661 tcgttgtgag attgactcgg ctatccctga gaaacggggg atgggttcgt cagcggctat
    21721 cagcatagcg gccattcgtg cggtatttga ctactatcag gctgatctgc ctcatgatgt
    21781 actagaaatc ttggtcaatc gagctgaaat gattgcccat atgaatccta gtggtttgga
    21841 tgctaagacc tgtctcagtg accaacctat tcgctttatc aagaacgtag gatttacaga
    21901 acttgagatg gatttatccg cctatttggt gattgccgat acgggtgttt atggtcatac
    21961 tcgtgaagcc atccaagtgg ttcaaaataa gggcaaggat gccctaccgt ttttgcatgc
    22021 cttgggagaa ttaacccagc aagcagaagt tgcgatttca caaaaagatg ctgaaggact
    22081 gggacaaatc ctcagtcaag cgcatttaca tttaaaagaa attggagtca gtagccctga
    22141 ggcagacttt ttggttgaaa cgactcttag ccatggtgct ctgggtgcca agatgagcgg
    22201 tggtgggcta ggaggttgta tcatagcctt ggtaaccaat ttgacacacg cacaagaact
    22261 agcagaaaga ttagaagaga aaggagctgt tcagacatgg atagagagcc tgtaacagta
    22321 cgttcctacg caaatattgc tattatcaaa tattggggaa agaaaaaaga aaaagagatg
    22381 gtgcctgcta ctagcagtat ttctctaact ttggaaaata tgtatacaga gacgaccttg
    22441 tcgcctttac cagccaatgt aacagctgac gaattttaca tcaatggtca gctacaaaat
    22501 gaggtcgagc atgccaagat gagtaagatt attgaccgtt atcgtccagc tggtgagggc
    22561 tttgtccgta tcgatactca aaacaatatg cctacggcag cgggcctgtc ctcaagttct
    22621 agtggtttgt ccgccctggt caaggcttgt aatgcttatt tcaagcttgg attggataga
    22681 agtcagttag cgcaggaagc caagtttgcc tcaggctctt cttctcggag tttttatgga
    22741 ccactaggag cctgggataa ggatagtgga gaaatttacc ctgtagagac agacttgaaa
    22801 ctagctatga ttatgttggt gctagaggac aagaaaaaac caatctctag ccgtgacggg
    22861 atgaaacttt gtgtggaaac ctcgacgact ttcgacgact gggttcgtca gtctgagaag
    22921 gactatcagg atatgctgat ttatctcaag gaaaatgatt ttgccaagat tggagaatta
    22981 acggagaaaa atgccctggc tatgcatgct acgacaaaga ctgctagtcc agccttttct
    23041 tatctgacgg atgcctctta tgaggctatg gactttgttc gccagcttcg tgagaaagga
    23101 gaggcctgct actttaccat ggatgctggt cccaatgtta aggtcttctg tcaggagaaa
    23161 gacttggagc atttatcaga aattttcggt cagcgttatc gcttgattgt gtcaaaaaca
    23221 aaggatttga gtcaagatga ttgctgttaa aacttgcgga aaactctatt gggcaggtga
    23281 atatgctatt ttagagccag ggcagttagc tttgataaag gatattccca tctatatgag
    23341 ggctgaaatt gctttttctg acagctaccg tatctattca gatatgtttg atttcgcagt
    23401 ggacttaagg cctaatcctg actacagctt gattcaagaa acgattgctt tgatgggaga
    23461 cttcctcgct gttcgcggtc agaatttaag acctttttcc ctaaaaatct gtggcaaaat
    23521 ggaacgagaa gggaaaaagt ttggtctagg ttctagtggc agcgtcgttg tcttggttgt
    23581 caaggcttta ctggctctct ataatctttc ggttgatcag aatctcttgt tcaagctgac
    23641 tagcgctgtc ttgctcaagc gaggagacaa tggttccatg ggcgaccttg cctgtattgt
    23701 ggcagaggat ttggttctct accagtcatt tgatcgccag aaggtggctg cttggttaga
    23761 agaagaaaac ttggcgacag ttctggagcg tgattgggga ttttttatct cacaagtgaa
    23821 accaacttta gaatgtgatt tcttagtggg atggaccaag gaagtggctg tatcgagtca
    23881 catggtccag caaatcaagc aaaatatcaa tcaaaatttt ttaagttcct caaaagaaac
    23941 ggtggtttct ttggtcgaag ccttggagca ggggaaagcc gaaaaagtta tcgagcaagt
    24001 agaagtagcc agcaagcttt tagaaggctt gagtacagat atttacacgc ctttgcttag
    24061 acagttgaaa gaagccagtc aagatttgca ggccgttgcc aagagtagtg gtgctggtgg
    24121 tggtgactgt ggcatcgcct tgagttttga tgcgcaatca accaaaacct taaaaaatcg
    24181 ttgggccgat ctggggattg agctcttata tcaagaaagg ataggacatg acgacaaatc
    24241 gtaaggacga gcatatcctc tatgcccttg agcagaaaag ttcctataat agctttgatg
    24301 aggtggagct gattcattct tccttgcctc tttacaatct ggatgaaatc gatctttcga
    24361 cagagtttgc tggtcgaaag tgggactttc ctttttatat caatgccatg actggtggaa
    24421 gtaataaggg aagagaaatc aatcaaaagc tggctcaggt ggcggaatcc tgtggtattt
    24481 tatttgtaac gggttcttat agcgcagccc tcaaaaatcc aacggatgat tctttttctg
    24541 tcaagtctag tcatcccaat ctcctccttg gaaccaatat tggattggac aagcctgtcg
    24601 agttaggact tcagactgta gaagagatga atcctgttct attgcaagtg catgtcaatg
    24661 tcatgcagga attactcatg cccgagggag aaaggaagtt tagaagctgg caatcgcatc
    24721 tagcagatta tagcgagcaa attcccgttc ctattgtcct caaggaagtg ggctttggaa
    24781 tggatgccaa gacaatcgaa agagcctatg aattcggtgt tcgtacagtg gacctatcgg
    24841 gtcgtggtgg caccagcttt gcctatatcg aaaaccgtcg tagtggccag cgtgattacc
    24901 tcaatcaatg gggtcagtct accatgcagg cccttctcaa tgcccaagaa tggaaagata
    24961 aggtcgaact cttggttagt ggaggggttc ggaatccgct ggatatgatt aagtgcttgg
    25021 tttttggtgc taagtctgtg ggattgtcac gaaccgttct ggaattggtt gaaacctaca
    25081 cagttgaaga agtgattggc attgtccaag gctggaaagc agacctacgc ttgattatgt
    25141 gttcccttaa ctgtgccacc atagcagatc tacaaaaagt agactatctt ctttatggaa
    25201 aattaaaaga agcaaaggat cagatgaaaa aggcgtaacc agcgcctttt ttccatcctc
    25261 agactgaggt gacttttttg aattgtgata aaatagaagg gagaggatga acctatgaga
    25321 aaatttaaaa tctttttatt tatcgaagcc tgtcttctga caggagctct gattttgatg
    25381 gtatcagagc atttttcgcg ttttctgctg atactattcc tctttttgct tttgattcgc
    25441 tactacactg gtaaagaggg aaataatctt cttttagtag cggcaaccat tctcttcttt
    25501 ttcatcgtta tgctcaatcc ttttgtgatt ctagctattt ttgttgcggt tatctatagc
    25561 ctctttcttc tttacccgat gatgaaccag gaaaaagagc agaccaattt ggtttttgaa
    25621 gaggtcgtga cggttaagaa ggagaaaaat cgttggtttg gaaatcttca tcatttttca
    25681 agctaccaga cttgccaatt cgatgatatc aatctctttc gcttcatggg caaggacact
    25741 attcatctgg agagggtcat cttaaccaat catgacaatg tcattatcct cagaaagatg
    25801 gtaggaacga ccaaaatcat cgtacctgta gatgtggaag tcagtctcag cgttaactgt
    25861 ctctatgggg atttgacttt tttcaaccag cccaagcgag ccctccgcaa tgaacactat
    25921 catcaagaaa caaaagacta tctcaagagt aacaagagtg tcaagatttt cttgaccact
    25981 atgattggtg atgtggaggt ggttagagga tgaaaaaaca agcctatgtc attattgctc
    26041 tcacctcctt cctgtttgtc ttttttttct cccacagctt gctggaaata cttgattttg
    26101 actggtctat ctttttgcac gatgtcgaaa aaacagaaaa atttgtcttt ttattgttgg
    26161 ttttcagcat gtccataacc tgtctcttag ccctgttttg gcgagggatc gaagagcttt
    26221 ctctaagaaa aatgcaggct aatctcaagc gtttattggc agggcaagaa gtggttcagg
    26281 ttgcagatcc agatttggat gccagtttca agtccttatc aggtaaactt aaccttttga
    26341 cagaagctct tcaaaaagct gaaaatcata gccttgctca ggaagaggaa atcatcgaga
    26401 aggaacggaa gcgaattgct cgggatttgc acgatacagt cagtcaggag ttgtttgcgg
    26461 cccacatgat tttatcgggt atcagtcagc aggctttgaa attggataga gaaaagatgc
    26521 agatccagtt gcagagtgtc acagctattt tagaaactgc ccagaaggat ttgcgggttt
    26581 tgctcttgca tttgcgacca gttgaactgg agcagaagag cttgatagaa gggattcaaa
    26641 ttctcttaaa agagcttgag gacaagagtg atcttagggt tagtctcaag cagaatatga
    26701 cgaaattgcc taagaaaatc gaggagcata tcttccgtat cctgcaagag ttgattagca
    26761 atacgctccg ccatgcccag gcatcttgcc tagatgtcta cctctatcag acagatgttg
    26821 aattgcaact gaaggtggtg gacaatggga ttggtttcca gttagggagc ttagacgact
    26881 tgagttatgg actgcgaaat atcaaggagc gggttgaaga tatggcaggg acggttcagt
    26941 tattaacagc tcccaagcaa gggttggcag ttgatatccg tattcccctg ttagataagg
    27001 aatgataaag gagtaaagat gaaaatttta ctagtagatg accatgaaat ggtccgtttg
    27061 ggcttgaaaa gctactttga cctccaagac gatgtagaag ttgtgggtga ggcgtccaac
    27121 gggtctcaag ggattgactt ggccttggaa ctgcgtccag atgtcattgt catggatatt
    27181 gtcatgcctg agatgaatgg gattgacgcg accttagcaa tccttaaaga atggcctgaa
    27241 gccaagattt tgattgtgac ctcttatttg gacaatgaaa aaatcatgcc agtcttagat
    27301 gctggtgcca aaggctatat gctcaagact tctagtgcag atgaattgct tcatgccgtc
    27361 agtaaggtag ctgctggcga gctggccatt gagcaagagg ttagcaagaa ggttgaatac
    27421 caccgcaatc atatggaact tcatgaagaa ttgactgcgc gtgagcgaga tgttctccaa
    27481 ctcatcgcca agggctacga aaatcagcgc atcgcagatg acctctttat ctctctcaag
    27541 acggtcaaga cccacgtgtc caacattctt gccaaacttg aagtcagcga tcgtactcag
    27601 gcggctgtct atgcctttca gcaccatttg gtggggcaag aggagtttta gatgagttta
    27661 gcagatttac ttgaggagct agaagcagca aaagactcta aaaagcaagg cccatggaag
    27721 cctatatgcg ccatcaattt tcttttctag gtattgcggt gcctgaaaga aataaactct
    27781 ataaaaatat tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac
    27841 ttgctgggaa aaggagccta gaaaatacca atatgtggct gctaactatt tgaaagcaat
    27901 gcagtcttat ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc
    27961 ctggtgggac acggtagata tcctagatcg agtagtaggg agtttggtgt ataaacaccc
    28021 tgaactagaa gaaataatct taatattctt cgaaaatctc ttcaaaccac gtcagctcta
    28081 tctgcaacct caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgctctttg
    28141 attttcattg agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat
    28201 tgaccaccag ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctcct
    28261 tcataacttg aaccaaacag aattttttat caataaagcc attggctgga ctctgcgaga
    28321 ctactccaaa acgaatccca cttgggtaac atgctttatt gagaaaaaca aggaaagaat
    28381 ggctgaactt agtatcaaag aagcaagtaa gtacctctag cgtgattgaa aagcgcagtc
    28441 attaattgaa aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga
    28501 tttcttgatt ctatagtaga ttaagaaatt tagaatagta cgctataatt acattaggag
    28561 gacacaataa tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact
    28621 ttattggcta gccagttatc gacagtatct gctttgagtg ttatttctag tacaggtgaa
    28681 gaatatgagg taagtgagac actagaaaaa ggtccagagt ctaatgattc ttcattatct
    28741 gagatttcac caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg
    28801 atgatttgat taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt
    28861 tatctaagta ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt
    28921 ttattaaaga taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga
    28981 aagaagcgga tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa
    29041 agatcaaagt aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg
    29101 caagggaata tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga
    29161 ctttgggtct tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct
    29221 atccatcata taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg
    29281 atgatggcat gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag
    29341 tttatgatgc tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa
    29401 ttaacagtgc agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag
    29461 gttactctct tgaaggatgg tgaatgggtt aggtaatgaa ggctaattgt aaactgtgat
    29521 ggatacttaa ctttgtataa taggtggata aaagtcttta aaataggaaa aaacgcatat
    29581 tattaggtgt ttaaaaacct tgataatatg cgttttataa tggaaagatt tcttcaattt
    29641 cgtcttgtat agtagattga aactataata gtacacctct acttctaaaa cattgttaga
    29701 aattgatttg actgtcctga tcgatttgtc ctgttcttat ttcgttttac tataatgtaa
    29761 tcgtccaata acgaagtatt tttggatagt ccgaaaagtt tagcttcata tagagtaatt
    29821 ggtattagtg atagagtgtt agaaatttta aaagaatatc ttcttttaga agaaggtgat
    29881 tatatattta caaataatgg ttctccctta atgataactt gtttcaatta ctttttgaaa
    29941 aacagtttta ggaaaagtga aattaagaaa gatgattttg tattgactgc tcatgttttt
    30001 agatattcgc atataagttt gcttgctgaa ttggaagtac ctataacagc gataatggat
    30061 cgtgtagatt atactaatga aacaaagatt ttaagtgttt atactcatgt tactgagaag
    30121 atgaagtcaa atataactga aaaattagat aaattagttt tggaaaatga ctaaccaaaa
    30181 gatatccaaa gtagtctaaa attgtctata ctttatgagt gttttagtta g
//
LOCUS       DAVEHY010000027        30099 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVEHY010000027 DAVEHY010000000
VERSION     DAVEHY010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.027"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            100..1575
                     /locus_tag="VUZ44_001460"
     CDS             100..1575
                     /locus_tag="VUZ44_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU0320356.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1880..8581
                     /locus_tag="VUZ44_001461"
     CDS             1880..8581
                     /locus_tag="VUZ44_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU0320357.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGYYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVHYRADKDIEAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKIVAAVQENLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(8829..9681)
                     /locus_tag="VUZ44_001462"
                     /pseudo
     CDS             complement(8829..9681)
                     /locus_tag="VUZ44_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9893..10252)
                     /locus_tag="VUZ44_001463"
     CDS             complement(9893..10252)
                     /locus_tag="VUZ44_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU0320358.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            10344..11300
                     /locus_tag="VUZ44_001464"
                     /pseudo
     CDS             10344..11300
                     /locus_tag="VUZ44_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11284..11841
                     /locus_tag="VUZ44_001465"
     CDS             11284..11841
                     /locus_tag="VUZ44_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU0320359.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPAADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            11834..12088
                     /locus_tag="VUZ44_001466"
     CDS             11834..12088
                     /locus_tag="VUZ44_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320360.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAMGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12100..14154
                     /locus_tag="VUZ44_001467"
     CDS             12100..14154
                     /locus_tag="VUZ44_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU0320361.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14333..15193
                     /locus_tag="VUZ44_001468"
     CDS             14333..15193
                     /locus_tag="VUZ44_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU0320362.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSINFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQFLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQTLQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGVLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15404..16114
                     /gene="ccdA2"
                     /locus_tag="VUZ44_001469"
     CDS             15404..16114
                     /gene="ccdA2"
                     /locus_tag="VUZ44_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU0320363.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIIFLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16134..16700
                     /locus_tag="VUZ44_001470"
     CDS             16134..16700
                     /locus_tag="VUZ44_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU0320364.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16711..17823
                     /gene="msrB"
                     /locus_tag="VUZ44_001471"
     CDS             16711..17823
                     /gene="msrB"
                     /locus_tag="VUZ44_001471"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU0320365.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18181..18918
                     /locus_tag="VUZ44_001472"
     CDS             18181..18918
                     /locus_tag="VUZ44_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320366.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            18915..20606
                     /locus_tag="VUZ44_001473"
     CDS             18915..20606
                     /locus_tag="VUZ44_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU0320367.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            20722..21285
                     /locus_tag="VUZ44_001474"
     CDS             20722..21285
                     /locus_tag="VUZ44_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU0320368.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            21307..27618
                     /locus_tag="VUZ44_001475"
     CDS             21307..27618
                     /locus_tag="VUZ44_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEU0320369.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKVVEETPKQEESTPDTKAEETVEPKEE
                     TVNQSIEQPKVEQAGEPVAPREDEQAPTAPVAPREDEQAPTAPVEPEKQPEVPEEEKA
                     VEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYFTASYNALGPVLETAKGV
                     YASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADLKTKTKEHHSDTSWQNLQTE
                     VTEAEKVAANTDAKQSEVDSETASLKTAISGLNTDKAELENQLKIAQEKTETDFSMGS
                     WTVLSTAQNKAQEVKDNGTATQDQINEAEQNLKTALAGLTVDKSQLESKLTDTASKVS
                     TDYSKTSWEKMTVAKETATVVKENQEAKQSQIDESAKALETALADLSVDKTALGSAID
                     TATKKNKENYTNQTWAELETVLTAAKSVNTNESKQSEVNEAVEKLTATIEKLVELSEK
                     PILTLTSTDKKILEREAVAKYTLTSTKAKIKSITAELKKGDTVIHTVILAGDNLKEAA
                     LSAEFNNLEYYKEYTLSTKIVYDRGNGDVTETLENQNIQLDLKKIEIKNINQTSLISV
                     DADGNESDKSLLSEKPTDISSYYLKVTTHDNKVTRLAIDTIEEVEEGGKTLFKVTATA
                     PDLIQRNSENKLSETYTHYFEKQIPKVDNVYYNFNELITDMQKNPNGIFKLGADLNAA
                     NVKPKGKSYVTTKFRGELLSADGGHYTIHNIERPLLADAEGANIHDINLANVNINIAW
                     ADKVAPLGNMFKKSSIRNIKVIGTITGNNDVTGMVNKLDESNMRNVAFIGKINSLGNK
                     GWWSGGLVSESWISNVDNAYLDADIVGNNSKFGGLIAKLDHGVDQFTVGKKGYLKNSF
                     VKGTMKLTHHGESGGLIHNNFNWGVVEDTISMMKVTNGEIMYGSRDLNGDDQYFGLDN
                     FKRTFYVNGVSEGLMSYKKSNNIQGISKEQALEKFAKMGITAHEFTITEPIVNKLNGI
                     KPKADTYKDTQDYKADRELAYRNIEKFQPFYNKEWIVEQGNRLATGSSLMTKEVLSVT
                     GMKDGQFVTDLSEIDKIMIHYADGTKEELAVTAKTDSKVAQVKGYDVAGQNIIYTPNM
                     VMKNRNQLASGIKEKLASVTLLSDEVRSLMDQRDKPWKNTPDKKTEYIKGLYFEESFE
                     EVKGNLEKFVSKILENEDHQLNGGEVVERALLKKVEDNKAKIMMGLTYLNRYYDIKYG
                     DLSIKDIMMFKPDFYGKTPSVLDRLIQIGSREHFLKGDRTQDAYKEVIAGATGKGDLR
                     SFLDYNMRLFTEDKDLNDWFIHSAKNVYVVEPETSTEAFKDKRHRVFDGLNNDIHGRM
                     ILPLLNLKKAHIFMISTYNTLAYSSFERYGKNTEEARESLKPKIISVAKAQQRYLDFW
                     SRLALPSVRDKLLKSQNMVPTPVWDSQWYDGIPDANRQGYGRGGAVVSPIRELFGPTD
                     RWHQVNGAMGAMAKIYERPWKDEQVFFMVTNMLEDFGISAFTHETTHVNDRMAYLGGW
                     RHRPGTNVEAFAQGMLQSPSEIGHQGEYGALGLNMAYVRPNNGNQWYNPDPEKLQTRE
                     QIDRYMKNYNDALMMLDHLEADAVIPKVQDNISRWFKKMDRQYRSGNSGNQFDRVREL
                     NEDEKNNLVLNTIDDLVTNNLITKHGAPSDRIYNPEDFDSAYVNINMMTGIYGGNTST
                     GAPGAASFKHNTFRMWGYFGYENGFVGYASSKYQDAANKENNKMLGDDFIIKKVSNNR
                     FSTLEEWKKAYYQEVKAKADKGFTAIEIDGKQITNYAELKVLFDKAVEADLAGGGTAK
                     TVELKSKVFKALLKNTDGFSGDLFTTPQA"
     gene            27688..29409
                     /gene="pabB"
                     /locus_tag="VUZ44_001476"
     CDS             27688..29409
                     /gene="pabB"
                     /locus_tag="VUZ44_001476"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU0320370.1"
                     /translation="MHRKTVIDFRVLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQDYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLNKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            29410..29508
                     /locus_tag="VUZ44_001477"
                     /pseudo
     CDS             29410..29508
                     /locus_tag="VUZ44_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            29567..>30099
                     /locus_tag="VUZ44_001478"
     CDS             29567..>30099
                     /locus_tag="VUZ44_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU0320371.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDA"
BASE COUNT         9443 a         5502 c         6678 g         8476 t
ORIGIN      
        1 tccagtattt gacaatattg aagcagctat taaagaacat ggattaagct aattctaatt
       61 tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat ctttgaccta
      121 atcggaaagg ttttcaatcc catcttagaa atgggtggac ctgtcatcat gttgatcatt
      181 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
      241 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
      301 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat tacagacgtt
      361 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
      421 atcatgttga ttgtcaacgt agtgatgctt gctatgaaga aaaccgatac acttgatgtc
      481 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
      541 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
      601 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
      661 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
      721 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
      781 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
      841 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
      901 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
      961 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
     1021 ggtattacaa acgttgctac taaacgtctt cgaggacgta aattcaatat cggtcttgac
     1081 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
     1141 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
     1201 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
     1261 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac acttattgca
     1321 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
     1381 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
     1441 ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt ccttgtattc
     1501 tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga agagtacgca
     1561 gcaaaagcaa aataatgcgc tcctataaaa tataaactca atgaaaatca aagagcaaac
     1621 taggaaacta gccgcaggtt gctaaaaaca cagttttgag gttgtagata agactgacga
     1681 agtcagctca aaacatggtt ttgaggttgt agatgaaact gacgaagtca gtaatcatat
     1741 ctacggcaag gcgacgctga cgaagtttga attggatttt cgcagagtgt aaattgttga
     1801 aactaggttg tcataccatg tataccactt gggctttggt agtagctaac tgcactaaat
     1861 ataatataag gagggtttta tggggaaagg ccattggaat cggaaaagag tttatagcat
     1921 tcgtaagttt gctgtgggag cttgctcagt aatgattggg acttgtgcag ttctattagg
     1981 aggaaatata gctggagaat ctgtagttta tgcggatgaa acacttatta ctcatactgc
     2041 tgagaaacct aaagaggaaa aaatgatagt agaagaaaag gctgataaag ctttggaaac
     2101 taaaaatgta gttgaaagga cagaacaaag tgaacctagt tcaactgagg ctattgcatc
     2161 tgagaagaaa gaagatgaag ccgtaactcc aaaagaggaa aaagtgtctg ctaaaccgga
     2221 agaaaaagct ccaaggatag aatcacaagc ttcaagtcaa gaaaaaccgc tcaaggaaga
     2281 tgctaaagct gtaacaaatg aagaaatgaa tcaaatgatt gaagacagga aagtggattt
     2341 taatcaaaat tggcacttta aactcaatgc aaattctaag gaagccatta aacctgatgc
     2401 agacgtatct acgtggaaaa aattagattt accgtatgac tggagtatct ttaacaattt
     2461 cgatcatgaa tctcctgcac aaaatgaagg tggacaactc aacggtgggg aagcttggta
     2521 tcgcaagact ttcaaactag atgaaaaaga cctcaagaaa aatgttcgcc ttacttttga
     2581 tggcgtctac atggattctc aagtttatgt caatggtcag ttagtggggt attatccaaa
     2641 tggttataac cagttctcat atgatatcac caaatacctt cacaaagatg gtcgtgagaa
     2701 tgtgattgct gtccatgcag tcaacaaaca gccaagtagc cgttggtatt caggaagtgg
     2761 tatctatcgt gatgtgactt tacaagtgac agataaggtg catgttgaga aaaatgggac
     2821 aactatttta acaccaaaac ttgaagaaca acaacatggc aaggttgaaa ctcatgtgac
     2881 cagcaaaatc gtcaatacgg acgacaaaga ccatgaactt gtagccgaat atcaaatcgt
     2941 tgaacgaggt ggtcatgctg taacaggctt agttcgtaca gcgagtcgta ccttaaaagc
     3001 acatgaatca acaagcctag atgcgatttt agaagttgaa agaccaaaac tctggaccgt
     3061 tttaaatgac aaacctgcct tgtacgaatt gattacgcgt gtttaccgtg acggtcaatt
     3121 ggttgatgct aagaaggatt tgtttggtta ccgttactat cactggactc caaatgaagg
     3181 tttctctttg aatggtgaac gtattaaatt ccatggagta tccttgcacc acgaccatgg
     3241 ggcgcttgga gcagaagaaa actataaagc agaatatcgc cgtctcaaac aaatgaagga
     3301 gatgggagtt aactctatcc gtacaaccca caaccctgct agtgagcaaa ccttgcaaat
     3361 cgcagcagaa ctaggtttac tcgttcagga agaggccttt gatacgtggt atggtggcaa
     3421 gaaaccttat gactatggac gtttctttga aaaagatgcc actcacccag aagctcgaaa
     3481 aggtgaaaaa tggtctgatt ttgacctacg taccatggtc gaaagaggca aaaacaaccc
     3541 tgctatcttc atgtggtcaa ttggtaatga aataggtgaa gctaatggtg atgcccactc
     3601 tttagcaact gttaaacgtt tggtcaaggt tatcaaggat gttgataaga ctcgctatgt
     3661 taccatggga gcagataaat tccgtttcgg caatggtagc ggagggcatg agaaaattgc
     3721 tgatgaactc gatgctgttg gatttaacta ttctgaagat aattacaaag cccttagagc
     3781 taagcatcca aaatggttga tttacggttc agaaacatca tcagcaaccc gtacacgagg
     3841 aagttactat cgccctgaac gtgaattgaa acatagcaat ggacctgagc gtaattatga
     3901 acagtcagat tatggaaatg atcgtgtggg ttgggggaaa acagcaaccg cttcatggac
     3961 ttttgaccgt gacaacgctg gctatgctgg acagtttatc tggacaggta cggactatat
     4021 tggtgaacct acaccatggc acaaccaaaa tcaaactcct gttaagagct cttactttgg
     4081 tatcgtagat acagccggca ttccaaaaca tgacttctat ctctaccaaa gccaatgggt
     4141 ttctgttaag aagaaaccga tggtacacct tcttcctcac tggaactggg aaaacaaaga
     4201 attagcatcc aaagtagctg actcagaagg taagattcca gttcgtgctt attcgaatgc
     4261 ttctagtgta gaattgttct tgaatggaaa atctcttggt cttaagactt tcaataaaaa
     4321 acaaaccagc gatgggcgga cttaccaaga aggtgcaaat gctaatgaac tttatcttga
     4381 atggaaagtt gcctatcaac caggtacctt ggaagcaatt gctcgtgatg aatctggcaa
     4441 ggaaattgct cgagataaga ttacgactgc tggtaagcca gcggcagttc gtcttattaa
     4501 ggaagaccat gcgattgcag cagatggaaa agacttgact tacatctact atgaaattgt
     4561 tgacagccag gggaatgtgg ttccaactgc taataatctg gttcgcttcc aattgcatgg
     4621 ccaaggtcaa ctggtcggtg tagataacgg agaacaagcc agccgtgaac gctataaggc
     4681 gcaagcagat ggttcttgga ttcgtaaagc atttaatggt aaaggtgttg ccattgtcaa
     4741 atcaactgaa caagcaggga aattcaccct tactgctcac tctgatctct tgaaatctag
     4801 tcaagtcact gtctttactg gtaagaaaga aggacaagaa aagactgttt tggggacaga
     4861 ggtgccaaaa gtacagacca ttattggaga ggcacctgaa atgcctacca ctgttccgtt
     4921 tctatacagt gatggtagtc gtgcagaacg tcctgtaacc tggtcttcag tagatgtgag
     4981 caagcctggt attgtaacgg tgaaaggtat ggctgacgga cgagaagtag aagctcgtgt
     5041 agaagtgatt gctcttaaat cagagctacc agttgtgaaa cgtattgctc caaatactga
     5101 cttgaattct gtagacaaat ctgtttccta tgttttgact gatggaagtg tacaagagta
     5161 cgaagtagat agctgggaga ttacggaagt agataaagcc aaactttcag tagctggatc
     5221 acgtattcaa atgactggtc agttagctgg agaaactatt catgcaaccc ttgtggtaga
     5281 agaaggaaat gctgcagcac ctgtagtgcc aactgttact gttggaggtg aagcagtaac
     5341 aggtcttact agtcgacaac caatgcaata tcgtactcta tcttatggtg cccaattgcc
     5401 agaagtcaca gcaagtgctg aaaatgctga tgtgacagtt cttcaagcaa gcgcagcaaa
     5461 cggcatgcgt gcgagcatct ttattcagcc taaagatggt ggccctcttc aaacctatgc
     5521 aattcaattc cttgaagaag cgccaaaaat tgctcacttg agtttgcaag tggaaaaagc
     5581 tgacagtctc aaagaagacc aaactgtcaa attgtcggtt cgagctcact atcaagatgg
     5641 aacgcaagct gtattaccag ctgataaagt aaccttctct acaagtggtg aaggggaagt
     5701 cgcaattcgt aaaggaatgc ttgagttgca taagccagga gcagtcactc tgaacgctga
     5761 atatgaggga gctaaaggcc aagttgaact cactatccaa gccaatactg agaagaagat
     5821 tgcgcaatcc atccgtcctg taaatgtagt gacagatttg catcaggaac caagtcttcc
     5881 agcaacagta acagttgagt atgacaaagg tttccctaaa actcataaag tcacttggca
     5941 agctattccg aaagaaaaac tagactccta tcaaacattt gaagtactag gtaaagttga
     6001 aggaattgac cttgaagcgc gtgcaaaagt ctctgtagaa ggtatcgttt cagttgaaga
     6061 agtcagtgtg acaactccaa tcgcagaagc accacaatta ccagaaagtg ttcggacata
     6121 tgattcaaat ggtcacgttt catcagctaa ggttgcatgg gatgcgattc gtccagagca
     6181 atacgctaag gaaggtgtct ttacagttaa tggtcgctta gaaggtactc aattaacaac
     6241 taaacttcat gttcgcgtat ctgctcaaac tgagcaaggt gcaaacattt ctgaccaatg
     6301 gaccggttca gaattgccac ttgcctttgc ttcagactca aatccaagcg acccagtttc
     6361 aaatgttaat gacaagctca tttcctacaa taaccaacca gccaatcgtt ggacaaactg
     6421 gaatcgtagt aatccagaag cttcagtcgg tgttctgttt ggagattcag gtatcttgag
     6481 caaacgctcc gttgataatc taagtgtcgg attccacgaa gaccatggag ttggtgcacc
     6541 gaagtcttat gtgattgagt attatgttgg taagactgtc ccaacagctc ctaaaaaccc
     6601 tagttttgtt ggtaatgagg accatgtctt taatgattct gccaactgga aaccagttac
     6661 taatctaaaa gcccctgctc aactcaaggc tggagaaatg aaccacttta gctttgataa
     6721 agttgaaacc tatgctattc gtattcgcat ggttaaagca gataacaagc gtggaacgtc
     6781 tatcacagag gtacaaatct ttgcgaaaca agttgcggca gccaaacaag gacaaacaag
     6841 aatccaagtt gacggcaaag acttagcaaa cttcaaccct gatttgacag actactacct
     6901 tgagtctgta gatggaaaag ttccggcagt cacagcaagt gttagcaaca atggtctcgc
     6961 taccgtcgtt ccaagcgttc gtgaaggtga gccagttcgt gtcatcgcga aagctgaaaa
     7021 tggcgacatc ttaggagaat accgtctgca cttcactaag gataagaact tactttctca
     7081 taaaccagtt gctgcggtta aacaagctcg cttgctacaa gtaggtcaag cacttgaatt
     7141 gccgactaag gttccagttt acttcacagg taaagacggc tacgaaacaa aagacctgac
     7201 agttgaatgg gaagaagttc cagcggaaaa tctgacaaaa gcaggtcaat ttactgttcg
     7261 aggccgtgtc cttggtagta accttgttgc tgaggtcact gtacgagtga cagacaaact
     7321 tggtgagact ctttcagata accctaacta tgatgaaaac agtaaccagg cctttgcttc
     7381 agcaaccaat gatattgaca aaaactctca tgaccgcgtt gactatctca atgacggaga
     7441 tcattcagaa aatcgtcgtt ggacaaactg gtcaccaaca ccatcttcta atccagaagt
     7501 atcagcgggt gtgatcttcc gtgaaaatgg taagattgta gaacggactg ttgcacaagg
     7561 aaaagttcag ttctttgcag atagtggtac ggatgcacca tctaaactcg ttttagaacg
     7621 ctatgtcggt ccagagtttg aagtgccaac ctactattca aactaccaag cctacgacgc
     7681 agaccatcca ttcaacaatc cagaaaattg ggaagctgtg cattatcgtg cggataaaga
     7741 cattgaagcc ggtgatgaaa ttaacgttac ctttaaagct gtcaaagcca aagccatgag
     7801 atggcgtatg gagcgtaaag ctgacaagag cggtgttgcg atgattgaga tgaccttcct
     7861 ggcaccgagt gaattgcctc aagaaagtac gcaatcgaag attcttgtag atggaaaaga
     7921 gcttgctgat ttcgctgaaa atcgtcaaga ctatcaaatt acctataaag gtcaacggcc
     7981 aaaagtctca gttgaagaaa ataatcaagt agcttcaact gtggtagata gtggagaaga
     8041 tagccttcca gtacttgttc gcctcgtttc agaaagtgga aaacaagtca aggaataccg
     8101 tatccacttg actaaggaaa aaccagtttc tgagaagata gttgctgctg tacaagaaaa
     8161 tcttccaaaa ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga
     8221 ttcaacactg tatctaggtg aaactcgtgt agaacaagaa ggaaaagttg gaaaagaacg
     8281 tatctttaca gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga
     8341 agttccgaca gaccgcatcg tcttggttgg aaccaaacca gtagctcaag aagctaaaaa
     8401 accacaagtg tccgaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac
     8461 taataaagcc cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg
     8521 tttagctctt ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta
     8581 gaaattttga taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa
     8641 gataaagagt ctgggacaaa atagttctca accacaaaaa agctagatat ttccaattgc
     8701 ggaactctag ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagag
     8761 tagtacactt ctacttctaa aacattgtta gaaatcgatt tgactgtcct tatcgatttg
     8821 tcctgttctt atttcatttc actatgtttt aggaggttat tggccataag taccaatccc
     8881 atgtcaattc tcacttgacg cttgcctctc agattacatc tcttgtaacc caaacaagcc
     8941 tttatctgcc caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctatct
     9001 tggggagata aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata
     9061 tacagtccct tttgaggggc tgattcaggt tcatcagcgt agtaaacctt gatttcctgt
     9121 tgaaagtctg tctgtgttgg tacttgatat ggtgaaaacg atagcatcag ccatcaggat
     9181 gtatgtagct atcctccttg tcattatagt gccaattcgc taagttttta gctgactctt
     9241 tataccctct cttttgtttc ttatcaaaca tggcatattt aatcagaagg ggagtgattt
     9301 cttcttgaaa atagacttgt atctgttctt gaagtttggc ggagaatttc tctgtcgttt
     9361 tcttccacac aaaactatac ttgttggcat tggcttcaat cttagttccg tcaataaaca
     9421 aacaatctaa ggtcactaac tcttccattt ttcaattttt cgaccagaga aaatcccttg
     9481 tgaataggca aatagaagag tagatacaag cattttaggg tgataagacg ggcgatcaaa
     9541 ggcatgatag gaggtgtaga agtgacgttc ctccaaggta ttcaccactt tttcaatagt
     9601 aaagacgaga tggtcttgtg gtaagaagga actgatttct agtggtaaag ttgtttgatt
     9661 tgtgttatag tgaatatgca tgggatagcc tttttaaatg gtttattaag caattctatt
     9721 ttaccaagac tatcgtaacc atgcaaaaaa agcaacggca aatccgttgc tttttttgga
     9781 tataagagac tattgtccca gactcttttc tttgtataaa attgtatagt gttattgtct
     9841 atactatttt gtagagaaag caaaaatccc tagaaaatgc ttagggattc gactatttca
     9901 ttaagaacaa ttcaacaatc atttctatat acatgataag ggttaataag aatcctgcac
     9961 gccagaagaa tttgatgaat ttaggatagt aaaagctgcg ttttttcaaa aggaagaaaa
    10021 agacgagaat aatggctagg aacgagaggg ctagccccag tctagggagg aaattatggg
    10081 taaaggtttt agctgtaatc aagtaatact caaataccaa gactggaaaa gccaaatccg
    10141 caaagtttcg tcctagtttt tttaatctaa aaagtttggt taggataatg cagatgacta
    10201 aggtcagtat caataataaa atagatgcta atttcattaa aatcataccc atattgtatc
    10261 ataaaaaaag gctaatggaa acgagaaaca gaggaattta taggaaagtc aggcttttga
    10321 aattgtgggt gatttttgtt ataatgaaag ttataaaatc ttataatacc ttgaatgatt
    10381 attatcgaaa actctttgga gaaaagactt ttaaagtccc tattgatgcg ggatttgact
    10441 gtcccaatcg tgatggaact gtggctcatg gaggctgtac tttttgtacg gtttccggtt
    10501 ctggagatgc cattgtggca ccagatgcgc ctatccgtga gcaattttat aaggaaattg
    10561 actttattca tcgtaagtgg ccagatgttc agaagtatct ggtttatttt caaaatttta
    10621 ccaacaccca tgaaaaggtg gaagttattc gagagcgtta tgaacaggct atcaatgagc
    10681 caggtgtggt aggaatcaat attggaacgc gcccagactg tttaccagac gaaaccatcg
    10741 aatatttggc tgagttatcg gagtgcatgc atgtgacggt tgaattgggc ttgcaaacta
    10801 cttatgaagc aacctctgac ctgattaacc gtgcgcattc ttatgaattg taggtggaaa
    10861 cggtcaagcg tttgagaaag tatccaaaaa ttgagattgt ttcccatttg atcaatggtt
    10921 tgcctggtga aacccatgag atgatggttg aaaatgtccg ccgttgtgtc acggataacg
    10981 atattcaagg gattaaactg catttgctcc atcttatgac aaatactcgt atgcaacgag
    11041 attaccatga ggggcgttta caattgatga gtcaggacga atatgtcagg gtcatctgtg
    11101 accaactgga aattattccc aaacatatcg tcatccatcg aattacagga gatgcgccta
    11161 gggatatgct gcttggtcct atgtggagcc tcaataaatg ggaagtcctc aacagcattg
    11221 agatggagat gcgacgtcgt ggaagtgttc aaggatgcaa ggctgtaaaa caggagtttg
    11281 aaaatgaaaa gaccacttga gatggcacat gattttttgg ctgaggtcgt gacaaaagag
    11341 gatgtcgtag tggatgcgac tatgggaaat ggtcatgaca cgcttttttt agccaagcta
    11401 gccaagcaag tctatgcctt tgatattcag aagcaagcct tggaaaagac ccaagagcgt
    11461 ttgcatcagg ctgacttgac aaatgcccag ttaatcttgc aaggccatga gacactggac
    11521 cagtttgtga taaaagctaa ggcagggatt tttaatctgg gctatttgcc ggcagctgat
    11581 aagtctgtca tcacccgacc gcagacaacg attgaggcat tagaaaagct atgtggctta
    11641 cttgtcaaag gtggacgaat tgctattatg atttactatg gtcatgaagg aggcgatctc
    11701 gagagagatg ctgtcttgga ttttgtgatc cagttgaacc aacaagagta cacagctgcc
    11761 atttaccgaa ctttaaacca agtcaacaac ccgccgtttt tagtgatgat tgaaaaatta
    11821 gagagataca gacatggata aacaatactt acacgaaaag ctggatgcca tgcgccagaa
    11881 ttttgttgaa tcaacccacc acgaacgagc gatgggcgtg ctagaccaag cgcatatgag
    11941 caaaaaaatg cttaaaatca agaaaaaatt agttgctctt gaaatggaac ggtgccagag
    12001 aaaaattgag cacaaagact gttccaagat tgaccaaaaa atcaaagagc agaaggagat
    12061 atttgaatcc tgttgtaaaa aagattaagg aggacgtgcg tggaattact gatttacctc
    12121 atcctatttt tactggtttt gattgtctca agtacaacca ataagctcct gccctttttg
    12181 cctctccctt tggtgcaaat tcttttggga attgtgattg gtctcttttt acccaatact
    12241 gactttcacc ttaatacgga gttgtttttg gcactggtta tcggaccctt gcttttccga
    12301 gaggctgaag aagcagatgt tacggctatt ttaaaacact ggcgaatcat tgtttatctc
    12361 atatttccag tgatttttat ctcgaccctg agtttgggtg gcttggccca tcttctttgg
    12421 ttcagccttc ccttggcagc ttgcttggct gttggggcag cccttggtcc tacggacttg
    12481 gtggcctttg cctctctttc ggagcgtttt agctttccta agcgcgtgtc caatattctt
    12541 aagggcgaag gactcttgaa tgatgcttct ggtttggtgg cttttcaggt agctttgaca
    12601 gcttggacaa ctggagcttt ttctctgggg caagctagca gttcgctcat cttttcaatc
    12661 ctaggcggtt ttttaattgg atttttaaca gccatgacca accgcttcct ccataccttc
    12721 ttgctaagtg tgcgcgcaac ggatattgcc agtgaacttt tattagaatt gagtttgcct
    12781 ctagtgacct tctttctggc agaagaagtt catgtttcag gtattattgc cgtcgtagtt
    12841 gctggaattt taaaggcaag tcgcttcaag aaaatcacgc tcctcgaagc ccaagtggat
    12901 acggtgaccg agacggtctg gcatacagtg acctttatgc tcaacggttc tgtctttgtg
    12961 attttaggga tggagttgga aatgatagca gaacctatct tgaccaatcc aatctataat
    13021 cctctacttt tattgctatc tcttatcgcc cttacctttg tcctttttgt cattcgtttt
    13081 attatgatct atggctatta tgcctataga acccgacgcc tcaagaaaaa gctaaataag
    13141 tatatgaagg acatgtttct cttgaccttt tcaggtgtta agggaacggt gtcgattgct
    13201 acgattctct tgataccaag taatctagaa caggagtatc ctcttttgct tttccttgtt
    13261 gcaggtgtga cgcttgttag ctttttaaca ggtctcttgg tcttgcctca tctttctgat
    13321 gaagaggaag aaagcaagga ttatcttatg catatcgcca ttttgaatga agtaacgcta
    13381 gagttggaaa aagagttgga agacaccaga aataaacttc ccctctatgc ggctattgac
    13441 aattatcatg gacgtattga aaatctcatt ttaagccaag aaaaccagga tgatcaagaa
    13501 gactgggctg ctttgaaact cttgattctt agtattgaaa gtgatggttt ggaacaggcc
    13561 tatgaagagg ggaacattag caatcgtgct taccgagttt accaacgtta tctgaaaaat
    13621 atagaacaag gaatcaatcg taaacttgcc tcaagactga cctattattt tcttgtttcc
    13681 ttgaggattt tacgttttct ccttcatgaa gtttttactc ttggaaagac cttccgtagc
    13741 tggaaggaca aggagcaaag ccgtctccgt gctcttgatt atgaccaaat tgcagagctc
    13801 tatcttgcca atacagagat gattattgaa agtttggaaa acctgaaggg agtctacaga
    13861 cgctctttga ttagttttat gcaggagtct cgtcttcgag aaacaactat tatcagcagt
    13921 ggtgcctttg tcgaacgggt tatcaatcgt gtcaaaccca acaatatcaa tgaaatgctg
    13981 agaggctatt atctggagcg caagttgatt ttcgaatacg aagaaaaacg attaattaca
    14041 actaagtatg ccaagaaatt acgacaaaat gtaaataact tagagaacta ttccttgaag
    14101 gaagctgcca ataccctgcc gtatgatatg gtggaattgg taagaagaaa ttagttaata
    14161 ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ccgtatgtat gtgactgact
    14221 tcgtcagtct tatctacaac ctcaaaacag tgttttgagc agcttgcggc tagctttcta
    14281 gtttgctctt tgattttcat tgagtataag attataaatg aaggagtatg acatgaaaaa
    14341 gtggtggaaa gagctgatag acaagccttt attaaaagct tttttgcatt attatcaagc
    14401 atcagatagt gagttgacca gtgtcgcagt agcctactat tggttgattt cgattttccc
    14461 cctgcttttg gtggtggtca atatcctccc ctattttcag attcctgtgg gagaatttct
    14521 gggctttatg aaagacgtcc tgcccccaag cctctatgaa ggtgtggaaa aaatagccag
    14581 agaagtcttg acgcaacctt caacaggttt attgagtttt tctgttttat cggcgttatg
    14641 gagtttttca aaatctataa atttcttgca aaaagctttt aacaaggctt atggcgtcga
    14701 aaagagtcgt ggacttattt cccatcagat gctaagtctc ctagtcagtt ttggcttgca
    14761 gttcctcttt gcgtttgcct tgtttttgat cttatttggt cagatgattt tggctttact
    14821 tgctcattat tggacaaaag atggcattat ctatcagact ttacaagggt tggcaggtcc
    14881 tctgatttac gccctcctct ttgctatctt ggtcatgctt tattattttc ttcccaatct
    14941 atctaacagg aaaattagct ataccctacc aggcagtgcc tttgttctct tggtgatttt
    15001 aggtgtacta actctgttct ctagttatct caattactat gtccatcatt tggtggatgt
    15061 ccgaatttta ggttccgttc ttcttgttgt tatgatgttt tggtttatct tgattgctaa
    15121 aattgttatc ctaggcgcgg ttatcaatgc cagtatgcag agtttgaaag atccggtctt
    15181 taaaaaagac taactattta tccattataa aagcgcatag tatcaagact ttatagaacc
    15241 ttgatactat gcgcttttgt gctttgacag ttttttgtat agtttttgtc caagatttct
    15301 aaatcatctg attaaattcc tattttcccc tatcattgtc cctgtttttt cgaaaatgga
    15361 aggagtataa taaatctatc aataaaatga taggaggaac tttatgggtc atattttctt
    15421 ttttctaagt gtctttttgg cagggattct atccttcttt tctccttgta tcttaccttt
    15481 gttaccggtc tatacaggag tgttactaga tgataaggat ggtgctcagg cttctagcgg
    15541 caaattttca atctcagtta ctagtttatt acgaactctg gcctttatag caggaatttc
    15601 ctttatattt attttgttgg gctatggagc tggtttttta ggcgatttgc tttatgcttc
    15661 ttggttccaa tatcttactg gggcaattat tatctttctt ggtttgcacc aaatggagat
    15721 tctacacttt aaggggcttt ataaagaaaa gaggctacaa ctgcaaggac aggggcaaaa
    15781 tggtaagggc tatagtcagg catttttatt gggcttgacc tttagttttg cttggacgcc
    15841 ttgcgtgggg ccggttctgg ggtctgtttt ggccttggcg gcttcaggtg gttcaggagc
    15901 ttggcaggga gctggtctca tgttggtgta tacgctgggc ttggcgctac cattcttgct
    15961 tctagctctg acctctagtt atgttttgaa acatttccga aaacttcatc cctatctcgg
    16021 aatcctcaaa aaagtgggtg gttttctcat tattgtgatg ggactcttgg ttctgtttgg
    16081 aaatgcttca attttaagtc aattatttga ataaaatgga aaggaatatc aatatgaaaa
    16141 aatggcaaac atgtgttctt ggagcaggtt cgctcctttg tttgacggct tgttcaggca
    16201 agtccgtgac tagtgaacac caaacgaaag atgaaatgaa gacggagcag acagctagta
    16261 aaacaagcgc agctaaaggg aaagaggtgg ctgattttga attgatggga gtagatggca
    16321 agacctaccg tttatctgat tacaagggca agaaagtcta tctcaaattc tgggcttctt
    16381 ggtgttccat ctgtctggct agtcttccag atacggatga gattgctaaa gaagctggtg
    16441 atgactatgt ggtcttgaca gtagtgtcac caggacataa gggagagcaa tctgaagcgg
    16501 actttaagaa ttggtataag ggattggatt ataaaaatct cccagtccta gttgacccat
    16561 caggcaaact tttggaaact tatggtgtcc gttcttaccc aacccaagcc tttatagaca
    16621 aagaaggcaa gctggtcaaa acacatccag gattcatgga aaaagatgca attttgcaaa
    16681 ctttgaagga attagcctag gaggtgtctt atgaatgata agttaaaaat cttcttgttg
    16741 ctaggagtat tttttctagc cataaccggt ttctatgttc tattgatacg aaatgcaggg
    16801 cagacagatg cctcgcaaat tgaaaaggcg gcagttagcc aaggaggaaa agcagtgaaa
    16861 aaaacagaaa ttagtaaaga cgcagacttg cacgaaattt atctagctgg aggttgtttc
    16921 tggggagtgg aggaatattt ctcacgcgtt cccggggtga cggatgccgt ttcaggctat
    16981 gcaaatggta gaggagaaac aaccaagtac gaattgatta accaaacagg tcatgcagaa
    17041 accgtccatg tcacctatga tgccaagcaa atttctctca aggaaatcct gcttcactat
    17101 ttccgcatta tcaatccaac cagcaaaaat aaacaaggaa atgatgtggg gacccagtac
    17161 cgtactggtg tttattacac agatgacaag gatttggaag tgattaacca agtctttgat
    17221 gaggtggcta agaaatacga tcaacctcta gcagttgaaa aggaaaactt gaagaatttt
    17281 gtggtggctg aggattacca tcaagactat ctcaagaaaa atccaaatgg ctactgccat
    17341 atcaatgtta atcaggcggc ctatcctgtc attgatgcca gcaaatatcc aaaaccaagt
    17401 gatgaggaat tgaaaaagac cctgtcacct gaggagtatg cagttaccca ggaaaatcaa
    17461 acagaacgag ctttctcaaa ccgttactgg gataaatttg aatccggtat ctatgtggat
    17521 atagcaactg gggaacctct cttttcatca aaagacaaat ttgagtctgg ttgtggctgg
    17581 cctagtttta cccaacccat cagtccagat gttgtcacct acaaggaaga taagtcctac
    17641 aatatgacgc gtatggaagt gcggagccga gtaggagatt ctcaccttgg gcatgtcttt
    17701 acggatggtc cacaggacaa gggcggctta cgttactgta tcaatagcct ctctatccgc
    17761 tttattccca aagaccaaat ggaagaaaaa ggctacgctt atttactaga ttatgttgat
    17821 taatactctt cgaaagtctc ttcaaaccac gtcagcgtcg ccttaccgta tgtagggtta
    17881 ctgactccgt cagttttatc tacaacctca aagctatact ttgagctgac ttcgtcagtt
    17941 ttatctacaa cctcaaagct atactttgag ctgacttcgt cagttttatc tacaacctca
    18001 aagcggtact ttgagctgac ttcgtcagtt ttatctacaa cctcaaagcg gtactttgag
    18061 aaacctgtgg ctatcttcct agtttacttt ttgattttta ttgagtataa gaggtctttc
    18121 ctaagcagtt agaggagaat tttgctatac tgatactagt aagtggtaaa ggagcagagc
    18181 atgacctaca caatcttaat cgtagaagat gaatatctgg taagacaagg tttgactaaa
    18241 ctggtcaatg tagcagccta cgatatggaa atcatcggtc aggctgaaaa tggaaggcag
    18301 gcttgggaat tgatccaaaa gcaggtgcca gatatcattt taaccgatat caacatgcct
    18361 catctaaatg gcatccagtt ggccagtctg gtacgagaaa cctatcctca ggttcatttg
    18421 gtctttttaa caggttacga tgattttgat tatgccttgt ctgctgtcaa actaggtgtg
    18481 gacgactacc tgctcaaacc cttttctcgt caggatattg aggaaatgtt ggggaaaatc
    18541 aaacaaaaac tagacaagga agagaaagaa gagcagttac aagatttatt gactaatagg
    18601 tttgaaggaa acatggccca gaaaatccag tctcatctgg ctgatagcca atttagttta
    18661 aagtctttag ccagtgactt aggttttagt ccgacctatc tgagttcctt gattaagaaa
    18721 gagttgggct tgccttttca ggattatctg gtgagagaac gtgttaaaca agctaagctc
    18781 ttgcttttaa ctacagatct gaagatttat gagatcgcag agaaggttgg ttttgaagat
    18841 atgaactatt ttacccaacg ttttaagcag attgcaggtg tgacacctcg tcagtttaag
    18901 aagggagaag accgatgaag cgttcttctc ttttagttag aatggttatt tccatctttc
    18961 tggtctttct cattctccta gctctggttg gaactttcta ctatcaatca agttcttcag
    19021 ccattgaggc caccattgag ggcaacagcc aaacgaccat cagccagact agccacttta
    19081 ttcagtctta tatcaaaaaa ctagaaacca cctcgactgg tttgacccag cagacggatg
    19141 ttctggccta tgctgagaat cccagtcaag acaaggtcga gggaatccga gatttgtttt
    19201 tgaccatctt gaagtcagat aaggacttga aaactgttgt gctggtgacc aaatctggtc
    19261 aggtcatttc tacagatgac agtgtgcaga tgaaaacttc ctctgatatg atggctgagg
    19321 attggtacca aaaggccatt catcagggag ctatgcctgt tttgactcca gctcgtaaat
    19381 cagatagtca gtgggtcatt tctgtcactc aagaacttgt tgatgcaaag ggagccaatc
    19441 ttggtgtgct tcgtttggat atttcttatg aaactctgga agcctatctc aatcaactcc
    19501 agttggggca gcagggcttt gccttcatta tcaatgaaaa ccatgaattt gtctaccatc
    19561 ctcaacacac agtttatagt tcgtctagca aaatggaggc tatgaaaccc tacatcgata
    19621 caggtcaggg ttatactcct ggtcacaaat cctacgtcag tcaagagaag attgcaggaa
    19681 ctgattggac ggtgcttggc gtgtcatcat tggaaaagtt agaccaggtt cggagtcagc
    19741 tcttgtggac cttgcttggg gccagtgtca catctcttct tgtctgtctc tgcttagtgt
    19801 ggttcagtct taaacgctgg attgctcctt tgaaggattt gagagaaacc atgttggaaa
    19861 ttgcttctgg tgctcaaaat cttcgtgcca aggaagttgg tgcctatgaa ctgagagaag
    19921 taactcgcca atttaatgct atgttggatc agattgatca gttgatggta gctattcgta
    19981 gccaggaaga aacgacccgt cagtaccaac ttcaagccct ttcgagccag attaatccac
    20041 atttcctcta taacactttg gacaccatca tctggatggc tgaatttcat gatagtcagc
    20101 gagtggtgca ggtgaccaag tccttggcaa cctatttccg cttggcgctc aatcaaggca
    20161 aggacttgat ttgtctctct gacgaaatca atcatgtccg ccagtatctc tttatccaga
    20221 aacaacgcta tggagataag ctggaatacg aaattaatga aaatgttgcc tttgataatt
    20281 tagtcttacc caagctggtc ctacaacccc ttgtagaaaa tgctctttac catggcatta
    20341 aggaaaagga aggtcagggc catattaaac tttctgtcca gaaacaggat tcgggattgg
    20401 tcatccgtat tgaggatgat ggcgttggct tccaagatgc tggtgatagt agtcaaagtc
    20461 aactcaaacg tgggggagtt ggtcttcaaa atgtcgatca acggctcaaa cttcattttg
    20521 gagccaatta ccagatgaag attgattcta gaccccaaaa agggacgaaa gttgaaatat
    20581 atataaatag aatagaaact agctaactcc cagtcaattc tgggagtttt atgcgtaatt
    20641 gggcaaactt tctaggttgt ctatcttgct aaaaacaaga aaaaacggta tgatagaaga
    20701 gtgacaacag aggtaacaga gatgaacgag acacagattc aaagagaaac acgtcaggta
    20761 gtggaagatg ttttagaaaa gaccaatttg aaacaggggg ccctttttgt tttaggtcta
    20821 tcttctagtg aggtgctagg tggtcagatt gggaaagaat ccagtcaaga gattggtgag
    20881 ctgatagtgg agactatctt gggtattcta ggtagtagag gtatccattt agcagttcaa
    20941 ggttgtgagc atgtcaatcg ggctctcgtt gttgaacgtc aggtggcaga gcagtttgat
    21001 ctggaaattg tcagtgtcca tcctactctt catgcaggag gttcggggca gttggcagcc
    21061 tttaagttta tgcaggatcc agttgaggtt gaatttatca aggctcatgc tggattggat
    21121 atcggagaca ctgcaattgg catgcatgtc aagcatgttc aggttccgat tcgccctatt
    21181 ttgagagaga ttggtcatgc ccatgtaacg gcactggcta gtcgtccaaa attaatcgga
    21241 ggtgcgcgtg cgcactatcc gcaagatgct attaggaagt cttgagaatg aataaaggag
    21301 ataaaagtgt ttaaaaaaga ccgtttttca attcgtaaga ttaagggagt tgtaggctct
    21361 gtatttcttg gaagcctttt gatggctcct tctgtagtgg acgcagccac ctatcactat
    21421 gtaaataaag agattatttc acaagaagct aaagatttaa ttcagacagg aaagcctgac
    21481 aggaatgaag ttgtatatgg tttggtgtat caaaaagatc agttgcctca aacagggaca
    21541 gaagcatctg ttttgacagc ttttggtttg ctgactgttg ggagcttgct tttaatctac
    21601 aagagaaaga aaattgctag cgtctttcta gttggagcta tgggattggt agttcttcct
    21661 agtgcagggg ctgtagaccc agttgcgacc ctagcgctgg ctagtcgaga gggtgttgtt
    21721 gaaatggatg gctatcgcta tgttggttat ctatcaggtg acatcctcaa aacgcttggc
    21781 ttggacactg ttttagaaga aacctcagca aaacctggag aggtgactgt agtcgaagtt
    21841 gagactcctc aatcaacaac aaatcaggag caagctagga cagaaaacca agtagtagag
    21901 acagaggaag ctccaaaaga agaagcacct agaacagaag aaagtccaaa ggaagaacca
    21961 aaatcggagg taaaacctac tgacgacacc cttcctaaag tagaagaggg gaaagaagat
    22021 tcagcagaac cagctccagt tgaagaagta ggtggagaag ttgagtcaaa accagaggaa
    22081 aaagtagcag ttaagccaga aagtcaacca tcagacaaac cagctgagga atcaaaagtt
    22141 gaacaagcag gtgaaccagt cgcgccaaga gaagacgaaa aggcaccagt cgagccagaa
    22201 aagcaaccag aagctcctga agaagagaag gttgtagagg aaacaccgaa acaagaagag
    22261 tcaactccag ataccaaggc tgaagaaact gtagaaccaa aagaggagac tgttaatcaa
    22321 tctattgaac aaccaaaagt tgaacaagca ggtgaaccag tcgcgccaag agaagacgaa
    22381 caggcaccaa cggcaccagt cgcgccaaga gaagacgaac aggcaccaac ggcaccagtt
    22441 gagccagaaa agcaaccaga agttcctgaa gaagagaagg ctgtagagga aacaccgaaa
    22501 ccagaagata aaataaaggg tattggtact aaagaaccag ttgataaaag tgagttaaat
    22561 aatcaaattg ataaagctag ttcagtttct cctactgatt attttacagc aagttacaat
    22621 gctcttggac ctgttttaga aactgcaaaa ggtgtctatg cttcagagcc tgtaaaacag
    22681 cctgaggtaa atagcgagac aaataaactt aaaacggcta ttgacgctct aaacgttgat
    22741 aaaactgaat taaacaatac gattgcagat ttaaaaacaa agacgaaaga acatcatagt
    22801 gatacaagtt ggcaaaacct tcaaactgaa gtcacagagg ctgaaaaagt tgcagctaat
    22861 acggatgcta aacaaagtga agtagattct gagactgcaa gtcttaaaac agcaatttct
    22921 ggattaaata cagataaagc tgaactcgaa aatcaactta agattgcaca ggaaaaaact
    22981 gaaactgatt tcagcatggg atcttggacg gttttgagta cagctcaaaa taaagctcag
    23041 gaagtaaaag ataacggcac agcgacccaa gaccaaatca acgaagcaga gcaaaatttg
    23101 aaaacagccc tcgctggttt gactgttgat aagtctcaac ttgaaagcaa acttacagat
    23161 acggcatcta aggtttcaac agactacagc aagactagtt gggagaagat gactgtggct
    23221 aaagaaaccg ctactgttgt taaggagaat caagaagcca agcaatcaca aatagatgaa
    23281 tcagcaaaag ctttggaaac agcccttgct gacttatctg ttgacaaaac agctttggga
    23341 agtgctatcg atacagctac caagaaaaat aaagagaact atacaaatca aacatgggca
    23401 gagttagaaa cagttcttac agcagcaaaa tctgtaaaca ctaacgagtc taaacaaagt
    23461 gaagttaacg aagctgttga aaaattaact gcaactattg aaaaattggt tgaattatct
    23521 gaaaagccaa tattaacatt gactagtacc gataagaaaa tattggaacg tgaagctgtt
    23581 gctaagtata ctttaacttc aacaaaagct aaaatcaaat caatcacagc tgaattgaaa
    23641 aaaggtgata ctgttattca tacggtgata ttagcaggag ataatctgaa agaagctgct
    23701 cttagtgcag aatttaacaa cttagaatat tataaggaat atactttatc tacgaaaata
    23761 gtttacgata gaggtaacgg tgacgtaaca gaaactctag aaaatcaaaa tattcaatta
    23821 gatcttaaaa aaattgagat taaaaacatc aatcaaacaa gtttaataag tgttgatgct
    23881 gatggtaatg aatcagataa aagtttatta tcagaaaaac caacagacat ttcatcatat
    23941 tacttaaaag ttacaactca cgacaacaaa gtgacaagac ttgctatcga tacgattgaa
    24001 gaagtagaag aaggtggtaa aactttattt aaagttactg ctactgctcc tgatttaatc
    24061 caacgcaaca gtgaaaataa gctaagcgaa acttacactc actacttcga aaaacaaata
    24121 ccaaaagtag ataatgtata ttataacttt aacgagttaa ttacagatat gcaaaaaaat
    24181 cctaatggca tattcaaact tggtgcagat cttaatgcag caaatgtaaa acctaaaggg
    24241 aaatcttatg taactactaa gtttagagga gaattattaa gtgctgatgg cggtcattat
    24301 acaattcata acatagaacg tcctctattg gctgatgctg aaggagctaa catccatgac
    24361 attaatcttg cgaatgtaaa tattaatata gcttgggcag ataaagttgc tcctcttggt
    24421 aatatgttta aaaaatcaag tattagaaat ataaaagtta tagggactat caccggtaat
    24481 aatgatgtta ccggtatggt taacaaactt gatgaatcaa atatgagaaa cgttgcattt
    24541 ataggtaaaa ttaatagcct tggtaacaaa ggttggtggt ctggaggact tgtgagtgaa
    24601 agttggataa gtaatgttga taacgcttat ctagatgccg atattgtagg taataattcc
    24661 aagttcggtg gattaatcgc caagttagat catggcgtag accaattcac agttggtaaa
    24721 aaaggatact tgaaaaactc atttgttaaa ggtacaatga aacttactca tcatggtgag
    24781 agtggtggat taattcataa caatttcaac tggggagttg tagaagatac tatcagtatg
    24841 atgaaagtaa caaacgggga aatcatgtat ggttcacgtg atttaaacgg agatgatcaa
    24901 tacttcggtt tagataattt caaacgaact ttctatgtca atggtgtctc tgagggatta
    24961 atgtcttata aaaaatctaa taatatccag ggtatctcta aggagcaggc actagaaaaa
    25021 tttgctaaaa tggggattac cgctcatgaa tttacaatta ccgagccaat tgtaaataaa
    25081 cttaacggta taaaaccaaa agctgatact tataaagata ctcaagatta caaagcagac
    25141 cgcgaacttg cttatcgaaa cattgaaaaa tttcaaccat tctacaataa agagtggatt
    25201 gtagagcaag gtaatagatt ggctacaggt tcaagcctaa tgactaaaga agtgttatct
    25261 gtaacaggta tgaaagatgg tcaatttgtg actgacttat cagaaattga taaaattatg
    25321 attcactatg ccgatggaac caaagaagag ttagctgtaa ctgctaaaac ggactctaaa
    25381 gtagctcaag taaaagggta tgatgtggca ggtcaaaaca ttatctatac tccaaatatg
    25441 gttatgaaga atcgtaacca gttagcaagc ggtattaaag agaagttagc tagtgttacc
    25501 ttactttcag atgaagttcg tagcttgatg gatcagcgtg ataaaccttg gaagaacaca
    25561 ccagataaaa aaactgagta tattaaaggc ttgtatttcg aagaaagctt tgaagaagta
    25621 aaaggaaact tagaaaaatt tgttagtaag attttagaaa atgaagatca tcagttaaat
    25681 ggtggggaag tagttgagcg tgctttactt aagaaagttg aagataacaa agctaaaatt
    25741 atgatgggac tgacttatct taatcgttac tatgatatca aatatggtga tttgagtatc
    25801 aaagatatta tgatgtttaa acctgacttt tatggtaaga caccaagtgt attagatcgt
    25861 ttgattcaaa ttggttcaag ggagcatttc ttgaaaggtg accgtacaca agatgcttac
    25921 aaagaagtga ttgctggtgc aactggtaaa ggtgatttac gtagcttctt agactataac
    25981 atgcgtttat ttacagaaga taaagatttg aatgactggt ttattcattc tgcgaaaaac
    26041 gtttatgtag tagaacctga aacaagtaca gaagccttta aagataagcg tcaccgtgta
    26101 tttgatggtt taaacaatga tattcacggt cgtatgattt taccattgct caacttaaag
    26161 aaagctcata tctttatgat ttcaacctat aacactttag cttatagttc atttgagaga
    26221 tatggtaaaa atacagagga agcgagagag tctttaaaac ctaagattat ttcagtagca
    26281 aaagcacaac aaagatacct agacttttgg tctcgtttag ctcttccaag tgtacgtgat
    26341 aagctcctca agagtcaaaa tatggtaccg actcctgtgt gggacagtca gtggtatgac
    26401 ggtattcctg acgcaaatcg tcaaggttat ggacgaggtg gtgccgtggt atctcctatt
    26461 cgtgagctat tcggcccgac tgatcgttgg catcaagtta acggagcgat gggagcgatg
    26521 gcaaaaattt atgaacgtcc atggaaagat gaacaagttt tcttcatggt aacgaatatg
    26581 ttagaggact tcggtatttc agcatttacg catgaaacga cacacgttaa cgaccgtatg
    26641 gcttacttag gtggatggag acatcgtccg ggaactaatg ttgaagcgtt tgcgcaagga
    26701 atgttacaat cgccttctga aattgggcac caaggagaat atggagcgtt aggattgaat
    26761 atggcttacg ttcgtccaaa caatggaaat caatggtata atcctgaccc tgaaaaatta
    26821 caaactcgtg aacaaattga tcgctacatg aagaactaca atgatgctct tatgatgtta
    26881 gaccatcttg aggctgatgc ggttatccct aaagtacaag acaatattag ccgttggttc
    26941 aagaaaatgg atagacaata tcgtagtgga aattctggta atcagttcga tagagttcgt
    27001 gaattgaatg aagatgagaa gaataactta gttcttaata ctattgatga tttagttact
    27061 aataatttga taacaaaaca tggtgctcct agcgatagaa tttacaatcc tgaagacttt
    27121 gactctgctt atgtcaatat aaatatgatg actggtattt atggtggaaa tacaagtaca
    27181 ggtgcaccgg gtgcagcatc atttaaacat aatacattcc gtatgtgggg ttacttcgga
    27241 tacgaaaatg gatttgttgg atatgcttct agtaagtatc aagatgcagc taataaagaa
    27301 aataataaga tgttaggtga tgacttcatt atcaagaaag tatctaataa tagatttagt
    27361 actcttgaag aatggaaaaa agcttattat caagaagtga aggcaaaagc tgacaaagga
    27421 tttactgcaa ttgaaattga tggtaaacaa attactaatt atgctgagct aaaagtctta
    27481 tttgataagg cggttgaggc tgatctagca ggtggaggaa cagctaaaac tgtagagctt
    27541 aaatcgaaag tctttaaagc tctccttaaa aacacagacg gtttctctgg tgatctattt
    27601 actacaccac aagcataggg atgaataaaa tcgtaaaaag gtagattaag tttttcttga
    27661 tctgcctttt tatgctatac ttaaggtatg catagaaaaa cagtgattga ttttagggtt
    27721 ttgggggaga gatacacctt tacccagcct attaaagagt tgaaaacgag aaatgtagaa
    27781 gaagtggcag atttgctggc acaagtggaa agctaccaag agcaagatta ttatgtggtg
    27841 gggtatgtca gctacgaggc tgcacctgct tttgaggaaa aattagcagt tcacaaggat
    27901 cccctactgg gagagtacct gctttatttt actgttcacg atagggtaga gacctcccct
    27961 attcctctga cttatgagga tattgatttg ccctcaaatt ggcaggaagt aacgtctgca
    28021 gcagactatg aaaaggccat tgcccaaatt caccatcatt tacggcaggg agatacctat
    28081 caggtcaact acaccgtcca acttaagcaa aagttaaatg ccaatccttt tgccatctac
    28141 aatcgtatgg tggtagagca ggaggcgggc tacaatgcct atgtggaaca tgacgagatg
    28201 gcagtgattt ccatgagccc agagctcttt tttgagcaaa atgatcgcga gttgacaaca
    28261 cgaccaatga aggggacgac tcagcgtggg gtaactgacc aagaagatct tgaacaggcc
    28321 agttggttgg aacaggatcc caaaaatcgc tctgaaaata tgatgattgt ggacctcttg
    28381 cgcaatgata tgaaccgtat ttctgaagtt gggagcgagc acgtggagcg tctgtgtcag
    28441 gtagagcagt attcaactgt ttggcagatg acttcgacca tcaagagtca gttgcgagag
    28501 gatgtggacc ttgttgaaat cttccgctca ctctttcctt gtggttccat aacgggtgca
    28561 ccgaaaattg cgacaatgga gattatcaag gacttggagc ctcaaccgcg tggagtctac
    28621 tgtggaacga ttggtctctt gcttccaaat ggacgacgga tttttaatgt ggccattcgt
    28681 accattcaac ttcacaaagg tcaagccatt tatggagttg gcggagggat tacttgggat
    28741 agcacatggg aatctgaata ccgagaggtt catcaaaagg cagcagttct ttatcgtaaa
    28801 caagctcgct tccaactgat tacgacaggg gaaatcagcc agaagaacct gctgtttgaa
    28861 gatcaacatc tggaaagact gagaaaagct agtcgttatt ttgcttttcc ttttgatgca
    28921 gaagacttgg gacacaagat tgaggaagag tgtcaggatt gtgaagctaa tcgagattac
    28981 cgcttgcgaa tcagccttaa caaatctgga gagatagaag tcaatcgtca agtattaacc
    29041 cctctcagta caagcttttg tcaggcccaa gtctgtcttc aggaagctgc tttgaatcaa
    29101 tcctttacct actttaaaac cactcaccga ccgcatttga gcctaggaga acaagagaag
    29161 atttaccaca ataagtcagg agaactgctt gaaacctcta taggaaattt ggttctgaaa
    29221 atcgctggaa aactctacac accgcctatc cgacttggaa tcttgccagg aatttaccgt
    29281 cagcatttgc tagaaacagg acaggtagaa gagaaagtct tgaccttggc agatttaacc
    29341 caagcagaag ctatttacgg ctgtaatgca gtgagaggct tgtatgaatt aagcctagag
    29401 gaaaattaga tgaaactggt atttttacac ggtttagggg agtcagcaga gtcttggaaa
    29461 gaagttcgga atcaattgaa ggataagccc acagagactc ttgaattgct gaaataagtt
    29521 tgataaaata atattgaaat cgatatcata attatgggag aaagaaatga ataaacgtct
    29581 atttttaaaa atgagtctgg tgacgttgcc aattttagcc ttgttttcac aaccagtttt
    29641 ggcggaagaa aacatccatt tttcgagctg taaggaagct tgggcgaatg gctattcgga
    29701 tattcacgag ggagaacctg gttattctgc caagttagac cgtgatcatg atggtgtggc
    29761 ttgcgaattg aaaaatgctc ctaagggtgc ttttaaagca aaacagtcaa cggctattca
    29821 aatcaacaca agttcagcaa caacaagtgg ttgggttaag caggacggcg cttggtacta
    29881 ctttgatgga aatggaaatc tagtgaaaaa tgcatggcag ggaagctatt acctgaaagc
    29941 tgatggtaaa atggcccaga gtgaatggat ttatgactct tcttatcaag cttggtatta
    30001 tttgaaatca gatggttctt atgcaaaaaa tgcatggcaa ggagcttatt accttaaatc
    30061 aaacggtaaa atggcacaag gtgagtgggt ttatgatgc
//
LOCUS       DAVEHY010000028        26407 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVEHY010000028 DAVEHY010000000
VERSION     DAVEHY010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26407
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.028"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..508)
                     /locus_tag="VUZ44_001479"
     CDS             complement(<1..508)
                     /locus_tag="VUZ44_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU0320372.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
     gene            complement(521..2014)
                     /locus_tag="VUZ44_001480"
     CDS             complement(521..2014)
                     /locus_tag="VUZ44_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU0320373.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            complement(2522..3688)
                     /locus_tag="VUZ44_001481"
     CDS             complement(2522..3688)
                     /locus_tag="VUZ44_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU0320374.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            complement(3701..4440)
                     /locus_tag="VUZ44_001482"
                     /pseudo
     CDS             complement(3701..4440)
                     /locus_tag="VUZ44_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(4462..5286)
                     /locus_tag="VUZ44_001483"
     CDS             complement(4462..5286)
                     /locus_tag="VUZ44_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU0320375.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     LYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(5423..6637)
                     /gene="thiI"
                     /locus_tag="VUZ44_001484"
     CDS             complement(5423..6637)
                     /gene="thiI"
                     /locus_tag="VUZ44_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU0320376.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(6646..7788)
                     /locus_tag="VUZ44_001485"
     CDS             complement(6646..7788)
                     /locus_tag="VUZ44_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU0320377.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGI
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            7926..8354
                     /locus_tag="VUZ44_001486"
     CDS             7926..8354
                     /locus_tag="VUZ44_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320378.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            complement(8399..10624)
                     /locus_tag="VUZ44_001487"
     CDS             complement(8399..10624)
                     /locus_tag="VUZ44_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU0320379.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(10788..12740)
                     /locus_tag="VUZ44_001488"
     CDS             complement(10788..12740)
                     /locus_tag="VUZ44_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU0320380.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTYLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(12737..13648)
                     /gene="pfkB"
                     /locus_tag="VUZ44_001489"
     CDS             complement(12737..13648)
                     /gene="pfkB"
                     /locus_tag="VUZ44_001489"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU0320381.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLDIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(13645..14385)
                     /locus_tag="VUZ44_001490"
     CDS             complement(13645..14385)
                     /locus_tag="VUZ44_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU0320382.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            14547..14634
                     /locus_tag="VUZ44_001491"
     tRNA            14547..14634
                     /locus_tag="VUZ44_001491"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14581..14583,aa:Ser,seq:gga)
     gene            complement(14817..15164)
                     /gene="ssrA"
                     /locus_tag="VUZ44_001492"
     tmRNA           complement(14817..15164)
                     /gene="ssrA"
                     /locus_tag="VUZ44_001492"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(15810..16919)
                     /locus_tag="VUZ44_001493"
     CDS             complement(15810..16919)
                     /locus_tag="VUZ44_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU0320383.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            17022..18263
                     /locus_tag="VUZ44_001494"
     CDS             17022..18263
                     /locus_tag="VUZ44_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU0320384.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKNLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(18494..19906)
                     /gene="sufB"
                     /locus_tag="VUZ44_001495"
     CDS             complement(18494..19906)
                     /gene="sufB"
                     /locus_tag="VUZ44_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU0320385.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANVGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(19960..20400)
                     /locus_tag="VUZ44_001496"
     CDS             complement(19960..20400)
                     /locus_tag="VUZ44_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU0320386.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(20387..21613)
                     /locus_tag="VUZ44_001497"
     CDS             complement(20387..21613)
                     /locus_tag="VUZ44_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU0320387.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(21624..22886)
                     /gene="sufD"
                     /locus_tag="VUZ44_001498"
     CDS             complement(21624..22886)
                     /gene="sufD"
                     /locus_tag="VUZ44_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU0320388.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGDDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(22914..23684)
                     /gene="sufC"
                     /locus_tag="VUZ44_001499"
     CDS             complement(22914..23684)
                     /gene="sufC"
                     /locus_tag="VUZ44_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU0320389.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(23834..24028)
                     /locus_tag="VUZ44_001500"
     CDS             complement(23834..24028)
                     /locus_tag="VUZ44_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU0320390.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(24056..25711)
                     /gene="dnaX"
                     /locus_tag="VUZ44_001501"
     CDS             complement(24056..25711)
                     /gene="dnaX"
                     /locus_tag="VUZ44_001501"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU0320391.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(25711..26208)
                     /locus_tag="VUZ44_001502"
     CDS             complement(25711..26208)
                     /locus_tag="VUZ44_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU0320392.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
BASE COUNT         7888 a         5795 c         4858 g         7866 t
ORIGIN      
        1 cgagcaagtt tagttcatct aactgcaatt ttcttttagt aataagccct ttaatcgtat
       61 taagaataca gataatgttc tcttgttctt cgatacctag caattctaat tgtaaatcaa
      121 gtaatatatt cttgtttaaa tgaggaattg ttgcacctgt tgaatgttct cgtaaatact
      181 gcgatttact ttccaaaaag actcccaagt aatctgatat aattttttct ttgtatcgct
      241 cattcttttt taagaccgta attgtactac caacagctcc cgataatcca taaccaactg
      301 ttcctgcatt agctccatcc catgctatca gaatatcatc tgggagtgct tcagtcatat
      361 ttaaactttc agtgaatttt aaattattat tatttcttaa atcatctatt tgaatataac
      421 gttggcttag agttgtttgt tcagcaagta cagtggcttt cttgcctttt tttagagata
      481 agacttcccc caacttcact tttttcatac agccacctcc ctacttgagt aatttttcta
      541 attcagccaa gccagcttga atttcttttt ctaaatcatt gattttcttt aagatgacct
      601 ctgttggttc atactcaact ttttcatact caatctcttt atatttattg atagacaaat
      661 cataatcatt ttcctttatc tcagcaactg gaacaaagaa agattgatcc gttctctgac
      721 gttctgcttc tttttcaaga tgatgaaagc gttcgataat atctggaata tcattgtcgc
      781 taatcggttg tcgcttatca tccaaactta aaccatccgc tttcatatcg taaaaccaga
      841 ctttgtcagt accaccatta ccagtttttg taaagatgag aatggcagtt gaaactccag
      901 cataaggctt gaaaacacca ctaggcattg agattacagc atcaagctta tgattctcta
      961 caatttcctg acgaattcct ttatgagctt tagacgaacc aaaaaggaca ccatcaggta
     1021 cgataactgc tgctcgtcca cctggtttta aagttcgcaa gaaaagagaa agaaagagta
     1081 attctgtttt tttggttttt acggttgcaa gaaggtcatt agaggttgaa ttgtagtcaa
     1141 gtgagccctt aaaaggagga tttgctaaaa ccaaagtata tttatcggct tcttcattat
     1201 cttgagacag cgagtcaagg taactgattt gtggattttc tactccatgt agcatcatgt
     1261 tcatcgcccc aagtctcaac atagtcgtat ccgtatcatt tccatgaaac atctgattat
     1321 gaaaatgatt gatattatct gtattggttt cccattcatc tttcttacgc tttaagtaac
     1381 ggctagcaga tactaagaag ccagcagaac ccatagcggg atctgagatg atatctttga
     1441 tagtcggttg catcaactca accatcatat cgatgatgtg acgaggtgta cggaactgtc
     1501 catttttacc tgcggtcgac aattttgata acagatattc atagatatct ccgatatcag
     1561 taatactttg tttgtcatta tcaaaatcta catctaatcc cctagttgga aaaacatcta
     1621 agatagaaat tgccttttga agcgtagcag gtttatttat ttgaaaaata gcttctcgca
     1681 tatatcgtga aaaggctgta tcatctgtat cccccttgag atttttaata aacggaaaaa
     1741 tctcctgagt cattaaacga taaacttcct gagcatctcc tatattttta aaagttgacc
     1801 aacggtattc aggtttatct tttggaaaaa ctccctcata aggaatccct agaaattcag
     1861 catcactttc acgtccaagc tcgacactat ccaaatcttt cataaataag agataagtca
     1921 actgttcaat atttgttaaa ggatttgcat ttccttctgt ccaaagaatt tcccacaact
     1981 gatcgatttt attttttaat tcgcctgtaa tcatatcttc ccttttcttt agtttttaaa
     2041 acttagtaat atcattattt tatcagattt caaacaaagc ttcaattaac tatatctatg
     2101 cgtcacctga atattttata ctcttcgaaa atctcttcaa accacgtcag cttcaccttg
     2161 ccgtaggtat atgatactga ctctgtcagt tctatccaca acctcaaaac agtgttttga
     2221 gaaacctgcg gctagcttcc tagtttgctc tttgattttc attgaatatt aatagacttg
     2281 tttggtatct tgaaaactat atcgtatagg tgtcgtcatg gatcctttta gctgatttaa
     2341 ggatacgcaa acacaatact atgactcaat tgaaatatta aaatttaatt tctgaccacc
     2401 taatcctgct tcaaatagtt atcgaacaag ttttatgata gctaccttgt tgggatgctc
     2461 ttatttttta tcagacaaaa caaaaggatt aagggagtta atttccttaa tccgatagtt
     2521 cttattcttg acgttgtccg aaatctgcaa tcatctgctc catttcttgt cgactcggag
     2581 tggtcagcat atacaggtaa tctccttgaa gttccgcgaa ggcagctggc atgacttttt
     2641 taaccttgaa ctgctggcta tatttggcaa gcaaatcctc ttctgaataa acatagtgag
     2701 catttgcacg gcgagaagta gccaaacaat actgagtttc aaagtctgac gctgggaact
     2761 cttctcctgc gacaatagct gcatagccac gataaaggtc caaggaatga gcaaagttat
     2821 aaacatcaat ggtaaaacca cctgcagggc ggttattgta ctcgatggta atataatcgt
     2881 ccccctcacg gaagaactca atatggaaaa accgttcttt cataccaaat tctttgacaa
     2941 ttgcttcccc atacttgcgc agtttaggat ccatatcctt gagcacataa taagaattgt
     3001 ccatcttata aatcatgagg tcaagcggtg tataggcgta gtcaaaggtt gttgagaaga
     3061 caatctttcc atccttgtcc acgagcccgt caaaggtaca gatttcgctg gaagtgacaa
     3121 atttttcaaa gaaataaagg gttgaatggt cccattcttg cttgaagtga ttgatatcgt
     3181 cttctgtctc aagtttaaag gttgcggctg ctcccactcc attatcaggt ttggcaatca
     3241 ttggaagacc gatttctttc actgcttgat caacatctgc ttccgtcttg ataacagctc
     3301 caggtaccac aggaacacct gcttttttga aaagtttctt catttcagac ttatatttcg
     3361 tctttttgag atcctctggt ttggcaccaa aaacattgaa ttgttctctg agtgttgcgt
     3421 ctagctcaag ccagtattca ttgtgagact cgatgcggcc aattggacca tgtttataaa
     3481 agagaaaagc aactgcacgt ttgacttcat ctatgttctc aagattatca acacgaaaat
     3541 actcggtcaa gctattgcgc aagggctcat ccaattgctc gtaagactct tgaccaattc
     3601 ccaagactgt gatgccttta ttagctagtt cgatggtaaa ctgttgaaag ttttgtggat
     3661 agtagggaga aataacaagg taattcatag gtaactcctt ttataaatag agattaccga
     3721 ggaaataagg catttgttta cgccaccatt cccagtcatg ggcgacatca tgtccccatt
     3781 cagcaaacca ggctggaatt tgtttcttgt caaaggcttc tttgagcttg taaaaggatg
     3841 gcaaaccatc ttgttcccag gctccaagcc ccgtacacag cacaatctct gcctgacggt
     3901 aacggtcaat aaaccagccg tcgttttggt tccaaatata atctactggc gagttttggt
     3961 aaatagcatc atcgttgtag taatcaccga caaagaaacg tgcgtcgtaa acaccactga
     4021 gagcaatcac tttggtaaag acatctggat gctggaggaa gaaattgagt gcatgatagg
     4081 ctcccataga gcaacctgtc gtcatcatgc catcaaacca acctgtcttg tgcttgataa
     4141 aagaatggcc tcctcaatca cataacgttc gtaggcacgg tgcatttccg cttggtcatg
     4201 agcatttttc caagtagcca accagctctc actatccaaa ctagataggg taaagaactg
     4261 gacaaggcct tcctcgataa aggaagcaca ggcatcaatc atgccaaaat catagtattc
     4321 gttgtgacta ccacctgatg aagcaaagac cacaactgga atcccaccat gtccataacg
     4381 gttaaggtac atttcacggt taagatgacc actccagtgg ctaagatgtt caatatgcat
     4441 ttcgtttttt cctttcttaa cttaccattt ttctgcaaaa aatctcagac aatctggtag
     4501 attttctgac caagggattt cactatggat ggcaccagac tgaactttta gcacaagatt
     4561 atccagatgt actccccctg ctatcaaatc atggtaatag caaagcgacg agtcgatata
     4621 ggcttgtttg atattgccat ccatcaaggt cttgtctgta tcatctgctt cttctgttcc
     4681 tacatagatg aagatacgct ggtcaggcga tagtttctgg cactcgatat agcggttaaa
     4741 ggcttcttgg tggagccagt ttgcagatga aaaaacgccc aagcaaccaa tttggtcttg
     4801 gtattccaaa ccgataaact gggtaatatt gcctcctagt gaggaaccaa tcatagccgt
     4861 atgctggcag tctgcttttg tacgataggt ctcatcgata aaaggcttga ccacctccat
     4921 gacaaactca gcatactcca cacccttacc accaaactgc tgctctggga taggagattc
     4981 ttggaacttc caagccgcat actcattcat tcgccccata ccatcattgt caatagcaac
     5041 gacaatcatg cgactgatat ccggatttcg tttgatagct gggataatct tccatgaata
     5101 tccaatgaaa gactctttgc tataaaaaac attttgcccg tcatgaaagt atagaacagg
     5161 ataggaacgg tctgtatctt tctcataatc tttaggaaga agaatacgta cacggcgctc
     5221 cttacctgta taaggaacct tgagtttgtg ttctttcatt tttagataaa agtaggattg
     5281 attcattgtc agaaaactct ctatattcaa aattttatat cattatatca tgaaaataga
     5341 aaaaaagtta gttttttacc tgtttttaga aaaaaaacta acttttttta ctgattttcg
     5401 ctattctttt ggattttctg aattagagta gattatcaat caagtcatca acttcatctt
     5461 tttcggcttg aggtgtgatt tcagtaatca tgattccagc cactgctcgc tcaaccaagc
     5521 cttcaacatc catacgcgct tcgtactgct ccgcattctt aattttagga tttgtttttg
     5581 gacgatctgg tgcaaaaatg gtacaacagt cttcaaacgg ttggattgaa atgtcaaagg
     5641 tatcgatttc ctgggcgatg tcaatgattt ccaacttgtc catggtaacc acaggacgaa
     5701 tgatgggagt gttggtaaca gcattgatag ccttcatact ttcaagggtt tggctggcta
     5761 cttgacctag actttcccca ttgatgataa ccaaaccatt tcgtacctca cgaatacggt
     5821 cagtaatccg catcataaag cgacgagtta gagtcatcaa ataagcttct ggcgctttgg
     5881 ctttgatttc ctcttgaatc tctgtgaaag gcacctcgat aaactggata tttccgccaa
     5941 acttggtcaa tttacgagtc aagtcctgcg ctttcttgag ggcaccagga ctagtatatg
     6001 gtggactagc aaagtgaact gcctcgatat ccaccccacg cttaagagca agataacctg
     6061 ctacaggtga gtcaatccct cctgacaaca tgagcatccc tttacctgaa gttccaactg
     6121 gcaaaccacc agccccacga atggtttcat aagaaagata ggctgcttct tcacgaatct
     6181 ccacctgaag attgatgtca ggacttttca tttgaacttg cacatttgga atggcttcga
     6241 atacagcccc tccaagtgtt tggttgagtt cacgactatc aagttcaaag ttgtggtcgc
     6301 tacgcttgct agaaatctta aaggtcatac cttccttgta gatgtcccgc ataatctctt
     6361 ggacagaaga cttcaaaact tctacagatt tttcaacctt ataaacagga gaaaagtttt
     6421 gaattccaaa aacttgtttg agagattctg caactgctgt gtaatcagct ccattgaggt
     6481 aagcgtgggc acggtcgcga tctgctgtta ccttaacttg ggtatagata gacaaaacgt
     6541 ccgaaatatt attacgaagt ttattgatga aacgcatacg gtttttaccc ttggttgaca
     6601 actctccgta gcgaatcata atttctgaat actgcatgaa tgctcctatc ttacttttct
     6661 agtttgattg taaatcaatt ttaacttggt caaaaactgc tcgacctgac tcatatcatt
     6721 ttccaagtct aggctaagac gcacagctga cttggcctta tctttgtcca ctcccatggc
     6781 aatcaagata ccggctggtt ttcctgcctt agatgaacaa gctgaggttg ttgagatgaa
     6841 aatatcatag tcttcaaagg cgtgaacgat gacttcacct cgaacacctt tgattccaaa
     6901 agtcagaata tgaggtgcaa agttttcctc atctgaaaag acaaaaatat ccggatagtt
     6961 cagaagagct tggcgaatca ctgccttcat ctgcccagtc ttgctcctaa agatatctag
     7021 cttttccata gacaaacgga gggccttggc tgtcgctgca atccctgcca cattttcagt
     7081 tgtcgaacga taatctcgct cctggccacc acctgtaaga agaggtgtaa tcttcttgcc
     7141 agatttgata tagacaaagc caacacctcg aaccccgtgg aacttgtgac tagagaaagt
     7201 cgcgcaatcc acccgttctg tcagatactt ttcagtcgga attttggcaa gcgcctgaac
     7261 cgcatcaacg tggaaggaaa tagtcggctt gtctgccaag aattctgaaa tagcctcaat
     7321 aggttggata gagccgattt cattgttcac agccatgatg gaaacgagga ttgtatcatg
     7381 ccgtatcaaa cctgctaacg cctcaacatc gaccaagcct ttcttatcaa ctggagcaaa
     7441 atccacttca aatccttgac ttttcaacca gagggctgac tctttgactg ctggatgttc
     7501 aatggctgaa acaatgatgt gcttgccaaa ctgagctttt tcaaaggcca cacccttgat
     7561 aagccagtta tccccttctg ttccacccga ggtaaagaag atttcatcgc ttttcttacc
     7621 gattaaatct gcaatctgtt ggcgagaagc atctaagatt cgtgttgctt ggtctcccaa
     7681 acgatggaga ctagatgggt ttcctaaaat ttttgaagcg acctgcatat aggtttcaag
     7741 ggcttcagga taaggcttgg tcgtcgctga attatcaaag taaatcatgt ttctcacgct
     7801 ttctaaaatc acttcctcta ttgtatcatg aaacggagct tgcgacaaga aagggaaatt
     7861 tctctttttt taagattttt ttaaagaaac agagtataat aaatcataat caaaggagag
     7921 aatgtatgtc taactatcgt agaacttcaa aaccaaaaac agaacacatc aaaaaaggct
     7981 ttacagtctt tcaaaaaacc gttgctacaa tcgctagtat ccttggcttg attaccgcaa
     8041 gtatcacgat tatgaacgcc ttggataata acaaaaatat taaaaaagaa cctacgacaa
     8101 gccagacgac aaccattgtc aaagaaatcc aaaaggaatc ccctaaggaa aacaccagtc
     8161 caactaaaga gactaacact agtcaagaaa aaacacagca agaggaaaca ccaaaatcta
     8221 gcgtcaagga agagaaaaaa gaagatcaga aaacagcaac tcaggactct tctactcctg
     8281 cttcaagtaa acctgctact gaaaacgaaa aacagtccaa tgcgccaact tcagaaaata
     8341 aaagcaatca atagccacta aaatagcttc cctccaaact tggaaagaag ctattttttt
     8401 attgttgtaa cacttttcga ggtttggtac cttcagctgg accgatgaca cctgctatct
     8461 ccagttcttc catgagacgg gtcgcacggt taaatccaac tgataaacga cgctgaatca
     8521 tagacgcact ggctttctgt gtttcgataa ccaaagactt agcttcttca aaaagcggat
     8581 caccaccagc atctccatcc gaaaattctc cttcattttc agaaacctca cctggatcaa
     8641 aactctcatc gtagtctgca tctgcctgag tcttgatgaa gttcacaatg cgctcaacat
     8701 cgtcatccga gataaaggag ccttggagac gaactggatg attttcatca atcggtttaa
     8761 agagcatgtc tcctcgacca agaagttttt ctgctccatt ttcatccaaa atcgtacggg
     8821 agtctgttcc tgatgaaacc gcaaatgcta cacgagatgg aacattggcc ttaatcaaac
     8881 cagagatgac atcaacagat ggacgctgag ttgcaagaat catgtggata cctgcagcac
     8941 gcgccttctg cccaagacgg atgatagcat cttccacttc cttgctggcc accatcatga
     9001 ggtcagccaa ctcatccaca atcacgacaa tgaatggtag cggaatttgc ttgtactcag
     9061 actgggaatt gaactcttct accttggcat taaaacctgc aatattccga actcccacct
     9121 tggcaaagag ttcataacgg ttttccattt catccacaac cttttgcaga gccttgctgg
     9181 ctttgcgtgg attggtcacg actggaatca agaggtgggg aatatcattg taaacagata
     9241 actcaaccat cttgggatcg accatcataa atttaacttg atctggtctc gccttcatga
     9301 gaatgctagc aataatgccg ttaactgcta ctgacttccc tgaacccgtt gaacctgcaa
     9361 ctagcaagtg gggcatttta gaaaggtcaa aagctcttgc ggttccatta acagccttcc
     9421 ctaaaggaat ttccaagaaa ttttctgctt tcgtttgcga ttgttcccat agttctcgga
     9481 aagatacagt ggcaatatcg gagttgggca cttcaattcc gattagggat ttcccaggga
     9541 ttggtgcttc aatccggaca tctttggcag ccaaggctag agcgaggtca tctgatagat
     9601 tggaaatgcg gttgaccctt acaccaacag ccggcttgac ttcatacttg gtcactgatg
     9661 gcccaatttc ggcccgttca actgttacct taataccaaa gctagcaaag gttgcttcta
     9721 agattttgat attttctctg acaattttct tctctttaga ctgatctttt ggtttatctg
     9781 gtgcaaagag ttgtaagctt ggaagtttgt attcaagggc ttctttggct gaaaaatcga
     9841 cctgaacatc ttggtcatct gagtcatctt cctgttcagg gaatttaagt tcagcttgag
     9901 gcaggatgat ttctggttcc acccactttt cttctggaat aggtggaaga ttttgaacag
     9961 cttcctctgt cagaatttca cccgtttcca tatcaacagg aggcaaatcg agtaaggctt
    10021 tttcagtctc ttcttgttct aatctagcct ctttctcagc cttttggcga gctttttctt
    10081 cttgtttgac aaagcgttcc tcttttcgac gctcgtgccc ttcccaccat ttggcaaagc
    10141 ctctactgaa aaattcagca atatcgtaaa cagaccaagg gctgactagg agagaaccca
    10201 ctaaaatcaa gatagaacca ataaagtaag ttccgatatt tgaaaagaga aaggctgttg
    10261 gaatataaag agcgaccccg atcaagcccc ctccagcaaa actagtcgtt cgaaaaccag
    10321 tcagatctgt cacaacctga gccatagtcc cttttagaac ggacttgtcc aaaccatatt
    10381 tccaaaccaa gtaggcctca aaaatcaaga gtaagccagc aaatatggtg aaaaagccag
    10441 ataagagtcc ttcctgtttt cgtatccact tgaaaaaaaa gagatagatt aataggccga
    10501 atatcgccag ataagctagg ctacccacta gcaagcgaat taaattataa agggttatac
    10561 ctgcagcccc taatttgaag gctgcgaaaa tcaataaaat cgcaattcct aacgaaatca
    10621 acattcgttg aatcgcttct tttctttcca gttctgcttt agacggtctc cgtcttgttg
    10681 tacttgtatt cttgtttgcc attcttctat tataccatat ttcacaggca tttcgggaag
    10741 agaaaaagac tgcaccaaac ggtccaatct tttcattttt ctatttttta tgcttgtggt
    10801 ttgcgtaggt aaccataaac cacaccactt acgattgctc ctaccaagac agaaacgagg
    10861 taaaggagag catttgaagt aagggcgata acgaagattc ctccgtgtgg cgccatgagt
    10921 ttgataccag taagaccaac gagtccacct gctactgctg aaccaaggat gaagcttgga
    10981 atcgcacgag ctgggtcagc ggcaccaaat ggaatcgctc cctcagtgat aaatgacaag
    11041 cccatgatga tgtttgtcaa accagagtta cgttcttcct tagtaaattt atctttgaaa
    11101 agaagagttg cgacaaagat tgcaagtggt ggcaccattc ctccagccat aactgctgcc
    11161 atggctacag aaccacctga agaaacagtt gctgcaagcg tacctgtacc aaagacataa
    11221 gctgctttat taactggtcc acccatgtca acagccatca ttccaccaag gacgatacca
    11281 agaaggacag ctgaacctcc tccaagaccg cctaggaagt cattcatagc agtgttgatt
    11341 gcagccattg ggatatttac agctagcata acaaatcctg tcaagattgt tccaagaagt
    11401 ggcaatagaa ggattgattt agcaccttcg agtgaacgag gaactttaac gtatttcttg
    11461 atggcaagaa ccaaggcacc tgcgataaat ccaccaacaa gggcacctag gaaaccagat
    11521 gagacacctg caagagttga agttgcttca ccacctgcgg cataaggaat tttaccaaag
    11581 gcaaaacctt ctttggcaat agcaccagcc acgaaacctg ctaccaaacc tggtttttca
    11641 gcaatagagt aggcaacata acccgcaaag actggaagca tcaaaccaaa ggcagctcca
    11701 ccaattttca tgaacataga agctaactca tggtaagaac caagattgcc aaggttttca
    11761 tttggaacac ccaaagcacc gtcaatcaag aaggcaaggg caatcatgat accaccaccg
    11821 ataacgaatg gtaacatttg agatacacca ctcatcaagt gtttgtagaa ggcaccacca
    11881 aggctttgtt tttcgttaga ggctgttgca gcttttgcac cattagcggc acggtagact
    11941 tcagtatctc ctgaaagagc caagttaatt agctcttctg tcttacggat accgtcagca
    12001 actggacgat tgatcaatgg ttttccatca aatcgatcca tttcaacggc cttgtctgct
    12061 gcaatgataa tagctttagc cttacggata tcttctgcag ttagttgatt tccaacaccg
    12121 ctagcaccgt tggtttcgac cttgatacca acccccattt cagcagctac tttttgaagg
    12181 gcttcttggg ccatgtaagt gtgggcaata cctgttgtac aagctgtaac agctacgata
    12241 aagtcaccag agtcattagc aggtgcttga acaagttcct cagttttttc tgaagcttgg
    12301 tcaaaaagtt cgataacttg gtctgcagat gttgcttgac gaagtttgtc tgcaaaaccg
    12361 tctttcatca agtattgaga caattctgcc aaggctgcca agtaagtatc attggcacct
    12421 tctggagctg caatcatgaa gaagaggtca gttgcttgtc catccaagct ctcgtagtca
    12481 acacccttat ttgacttagc aaatagaact gtcgcttctt tgacagcagc gtttttgctg
    12541 tgaggcattg cgattccatc acccaaacca gtagaagtca aagcttcacg cgccaaaatt
    12601 ccttctttaa atgtttcaaa atctgttaca taaccgtggt ctgtcaaatt tttaatcatc
    12661 tcgtcgatga cagctgtttt ttcagttgcc tgcaaatcta gcaacatgac atcttttctc
    12721 aataggtctt gaattttcat cgtttttcta cctcaacttt tccatatgtt tctttaataa
    12781 attccgccgt tgccaagtca tctgagaagg tagttgccgt tccgcaagcc actccccatt
    12841 tgaaggcttc tactgcgtct tttgatttga caaattcacc tgtgaatcca gcaaccatag
    12901 aatcaccagc tccaactgaa tttttgactg ttcccttgat tggtttagcg aagtaagctc
    12961 catcagatgt gacaagaagg gcaccatcac cagccataga gataataaca ttttgagcac
    13021 ccttagccag taactcacga gcgtatttct caatttcatc taaactttcg agtttaaccc
    13081 caaaaatcgc tccaagttca tgattgtttg gttttacaag aagaggctgg tagtccaaac
    13141 tatcaattaa ggtctgtcct tcaaagtcac agaccacttg cgcaccagtc tggcgcgtca
    13201 aggaaatcaa atccttatag ataacattgc ctagattttt agcacttgaa cctgcaaaga
    13261 caactgtatc ttctgctgtc agactagata aaatagcttt caattcttct agctgaaccg
    13321 attcaacagt tggacccgtt ccgttgattt ctgtttcttg gtctgctttg attttaacat
    13381 tgatacgagt atcttctgcc acttggacaa aacgtgtctc gatttcttcc tctgctagag
    13441 tatctgtgat aaatttacca gtaaagccac cgataaatcc cgtcgctgta ttaggaatat
    13501 ccaagcgttt caagacacgg ctgacattga ttcctttccc accagcaaac ttatcatcac
    13561 tgtccatacg atttacacta ccaactttga cttggtccaa acgaacgata tagtcaatgg
    13621 atggattgag tgtgactgta taaatcatac ttctattacc tccgttttct ccttaataac
    13681 ctgcaagagc tcatgccctt gactagtgat aacgatagcg cgtttgagtg gggctacctt
    13741 ggcaaagcaa gtttgtccaa tttttgacga atccaccaag acgtaggtct gcttggcatt
    13801 ctccaaaata gctcttttca cagctccctc ctccatatca ggagtcgtat aatagccatc
    13861 gtcaacacca ttcattccga taaaggcacg gtcaaagtgc aattggttaa tctggttaag
    13921 agcaacgcca ccgatactag catctgtcgc cgtcttgacg tttcctccaa ccatgacagt
    13981 tggaatctgc ttttcaacca actgagcggc atggtgaatg gagttggtca caactgtaat
    14041 attcttattg accaattcat gaatcaaaaa agcagttgtt gttccagcat cgataaagat
    14101 gacatctttt tctttaatga gagaggctgc tttctgagcc agcaacttct tttcttgaag
    14161 gtttttgaca gatttttctt gaatggtttc ttcttcctgt aaggagtggg ggagttctgc
    14221 tccaccatgc acacgacgaa gcttgttttc cgcttccaac tcatccaagt ctcttcgaac
    14281 cgttgattct gacgtttcta gcaaactaac taatttttct agagaaacta catgatgttg
    14341 atttaactcc tctaaaatca gttgcttccg ctctgttttt aacaccgaat cacctcctgt
    14401 tatcgtttac actattcatt ctatcatact ttcttttgaa gtcaagcatt ttttatcatt
    14461 ttctttcaaa atctatcatt tttcttattt ctagaatttt tattgcaaga taagagcctt
    14521 tatggtagac tatttgagta agtattggaa gattactcaa gaggcttaag aggccgtgtt
    14581 ggaaacgcgg taggcgtgta atagcgtgcg tgggttcgaa tcccatgtct tccgtcgaaa
    14641 aaagattatt tttaggatgc gacaaatgtt gtatcctttt ttctatcctt tttttaaaat
    14701 agggtctgtt tgtgactccc tttttagcaa aagaatgcaa atgaatacca aagataaaaa
    14761 taaaaaacgt tgatttaaca acgttttacc aaggaatgca aaagaatgca aaggaataat
    14821 ggagccggtg ggagtcgaac ccacgtccaa acacctgcca acatatttgt ctacaaccat
    14881 aggttatgta ttattttaac agcccctcga cacataactc aagtctagaa actgcgagtc
    14941 tatcaatctc ttatcaaacc gctagacaag gcttaatcgt atctcgctaa taataagacc
    15001 tgtcattgaa cacgagcaat ccaaatcggg tcacgcctgc tggtttttag gcagctagag
    15061 cgtaagaagt gttatttttt gcagttatat ttaactgagc gtttacgtcg ccacacgagt
    15121 cgcaaaatat gcctcataat gcctgtcgaa tccgtaacga ccccaaaaga caataaaacc
    15181 attatacctt atctaactca aaaatgcaaa aagaaatcac atacctaaaa aagatactat
    15241 tcgagaaatt tagcaaactg gaagactaac tacaactttc tcagtgcata actttacgat
    15301 tgtaaataga gcttacgaaa tccaattaac acatacctaa gatgaagcta tctgttttga
    15361 agaaattcac gaagagaatt attctaaaat actttcagat gagaattttc gtactctctt
    15421 tattttaatt catttgagtt taaaaactat aaaatcaatc cttatattat tcggactact
    15481 tttcacttat tgcaccaaaa tatagtaaaa tgaaataaga ataggacgaa tagatcagga
    15541 cagtcaaatc gatttctaac aatgttttag aattagaggt gtactattct agtttcaatc
    15601 tactataaat aggtttcatt cgaactttaa tagactatga aaaccagtgg aacttaccct
    15661 gacacggaat tccactggtt ttttcgattt ttatcagatt aacttctact attcttagct
    15721 gtgaaaatta gtttaagact ttaacttatt ttcagtcttc taatctaaag gccacttcca
    15781 gtaaagaaaa atcagggttc tcctgacttt tacttagcta attctctttc tcgttctttc
    15841 attattttat gattttcata caaacgggat aagaacttag aaatttcttt caagatagaa
    15901 taggttggca ctgcgacaat cattccaact acaccataga tattgcttga caacaaaagt
    15961 aaaactaaaa tcgtgattgg atgaaccttc ataacacttc ctacgattcg aggatataag
    16021 atattgccat ctacctgctg aacaacaagc atataaatca ctgcaatcaa cagtctatgg
    16081 ggatcagtga atatatttgc gatgatcata ggaatcaaac caatacttgg ccccacataa
    16141 ggaattaaat tggctacacc agaaaaaatg gcaaaaacta aagcatattt taaaccaata
    16201 atactatagc caatataagc taaacaacct ataatgattg cgtcaatcga aactccacta
    16261 atatagcgag caatcgtcgc atttaaattc tttaataagc ctgcaatatg caagcgatcc
    16321 ctctttagaa tcgttctttc aagcatgggc aagaatttat gtccatctaa taagaaataa
    16381 accaaaaaaa ctggagtcat aatcaaaatc aaaacagtac tgataagagc tgacaagacg
    16441 ctccccacac tatttgatac gctatttagg atattttgaa gaatatcaac ataggataag
    16501 tttaactgct gaattgtagc ttctacatcc aaattctgga gcgcaggata attagataag
    16561 tctatgatta agtcttgtac tcgactataa atagtttgac tagatataat caaactagat
    16621 aactgattaa tcaaaatagg taagagatag acaacaccta tgaccattcc ccagaccaaa
    16681 gtacacaagg taattaaaat accaagcaaa cgattgagtt tacagacttt atttaagaaa
    16741 gtaacaatag ggtttgtcaa ataataaaga aagcccccta ataaaaatgg gatcataatt
    16801 gtattaagca cgctaacaaa agggttaatc aaagacccca tctgtctcca taggtaaaag
    16861 atgatggtta agagtaaaat ttctgtggtc caaaaaaata atttatttct acgaaacatg
    16921 agttacctcc ctcactttat tttaccatat tttcaaaaag cttaacagat gaattattaa
    16981 agcaagaata ttttttttct ttatgataga ataaaactac tatgaaaaaa atatttttaa
    17041 ctttgttaac tgtctctctt ttagggggtg cttctactgc tgttgctcaa gattttacca
    17101 ttgccgctaa acatgcgatt gctgttgagg caaatactgg taaaattctc tatgagaagg
    17161 atgcaacgca acctgtcgaa attgcttcca taacaaaatt gattactgtt tatctggtct
    17221 atgaagcttt ggaaaacgga agtattaccc tctccactcc tgtagatatt tctgattatc
    17281 cttatcaatt gacgacaaat tctgaagcca gtaatattcc tatggaggcc cgtaattata
    17341 ctgtcgaaga gttgcttgaa gcaactctgg tatctagtgc caacagcgcc gctattgccc
    17401 tagctgagaa aattgctggc tcagaaaaag atttcgtcga tatgatgcgg gcaaaactct
    17461 tggaatgggg aattcaggat gccactgttg tcaatacgac aggtcttaac aatgaaactc
    17521 taggggataa catttaccca ggttctaaaa aagatgagga aaataagctt agtgcttatg
    17581 atgtcgctat cgttgctcgc aacctcatca aaaaataccc acaagtctta gaaatcacca
    17641 aaaaaccttc ttctactttt gctgggatga caatcacttc aaccaactac atgttagaag
    17701 gtatgcctgc ttaccgtggt ggttttgatg ggctaaaaac aggaacaaca gataaggctg
    17761 gagagtcttt tgttggtact actgtcgaaa aaggcatgag agtcatcaca gttgttttaa
    17821 atgcagatca tcaagacaat aatccttacg ctcgatttac agctacatct tccctaatgg
    17881 attatatttc ttctacattt acacttcgca aaatcgttca acaaggcgat gcctatcaag
    17941 atagcaaagc ccctgtacaa gatggaaaag aagatacagt aactgcagtg gctccagagg
    18001 atatctatct aatagaacgt gttgggaatc aatcttccca atctgttcaa ttcacacctg
    18061 attccaaagc aatcccagca ccacttgaag ctggaacagt ggttggccat ttgacttatg
    18121 aagacaagaa cttgattggt caaggttaca tcaccacaga gcgccctagt ttcgaaatgg
    18181 tagcagacaa gaaaattgaa aaagccttct tcttaaaagt ttggtggaat cagtttgtcc
    18241 gctttgttaa cgagaaatta taaaaaatcg cgattttaaa ccgcgatttt ttgatacaag
    18301 ttcatcttca aaatccttga ttttgagtaa atctaatact caaaatcaaa gaataaacta
    18361 ggaagctagc cgcaggttgc tcaaaacact gttttgaggt tgtagatgaa actgacgaag
    18421 tcagtaacca tacatacggt aaggcgatgc tgacgtggtt tgaagagatt ttcgaagagt
    18481 ataaaatcaa attttatcca actgatccct ccatttcata gctaatcaag cggttcagct
    18541 caactgcgta ttccattgga agttcttttg taaagggttc tacaaatccc atgacaatca
    18601 tttcagttgc ctcagattct gacaatccac ggctcatgag ataatacaat tgctcttctg
    18661 aaatcttaga tactttggct tcgtgttcca aagccacttg cgagttgtga atttcattaa
    18721 atggaatagt atctgatgct gacaagtcat ccatgataat ggtatcacat tcaatgtggg
    18781 aaacagattt cttagagttc ttgttaaagg tgacttgtcc acggtagtca acctttcctc
    18841 cacctttagc gatggattta gacacaatag acgagctggt atgtggagca ttgtgaatca
    18901 tcttagcacc cgtgtcttgg tgttgcccta cattagcaaa ggcgatagag agcatggtac
    18961 cacgcgctcc ttctccatca aggtaaacag atggatattt catagtcgtt ttggcaccca
    19021 agtttccatc aatccactca acagtggcat ccttttgagc cttagcacgc tttgttacca
    19081 agttatagac gttatcagac cagttttgga tagttgtata acgcatataa gctccgtcca
    19141 aagcaaaaat ttctacaatg gcagcgtgta agctattgct tgaatatgtt ggtgctgtac
    19201 atccttctac gtagtggacg cttgctccct catcaacgat aatcaaggta cgttcgaact
    19261 gacctatatt ttcgttattg atacggaaat aagtttgaag tggaatatct accttgacac
    19321 cttttggcac gtagataaaa gttccacccg accatactgc tgagttgagg gctgccaact
    19381 tgttatctgt cggcggtacc aacttcgcaa agtattgttt aaataagtct gggtattcct
    19441 tgagtgcgga atctgtatct gtaaagataa tacctaattt ttggaactct tccttcatgt
    19501 tgtggtaaac cacttctgac tcgtactggg cagaagcccc tgctaaataa gcacgttcag
    19561 cttctggaat cccgatacgt tcaaaggttt ctttaatctt ttcaggtaca tcatcccaag
    19621 aacgggctgg tttgtcagat ggtttttggt agtagattaa gtcatcaaag tcaatctctg
    19681 acaagtctgc tccccaagtt tgcatgggca tttttttgaa ggtttcataa gacttcaaac
    19741 ggaactccaa catccactca ggctcaccct tagcagcaga taattcacga ataacacctt
    19801 cgttgagtcc ttttcctgtc gataagacag gctctacatc gtcatggaaa ccaaatttat
    19861 attcaccaag gtcaattggt tttggttcta ctctttcttc agccatagta tcctttcttt
    19921 cttcatttct aataattcat aagacaaaag aaacttgtct tactgttttt cttgattttc
    19981 aattgttttc ttaagggcat tccaagctag ggttgcacac ttgattcttt gagggaattt
    20041 ggcaacacct gacaagaatg ccgcgtctcc aagttggcct tgacgctcat ctttttgccc
    20101 ctgaaccatt tcagaaaaaa tagtcgccag ttctaaaatt tcttgtttgg tttttcctaa
    20161 aacggcatct gtcatcatac tagcagaagc agttgaaatc gtgcatcctg aatttagaaa
    20221 agcaatatct tccaaacggt cctctgcatc aaacttgaca gagaggttga tgacatcccc
    20281 acaagtcgga ttgttgagac tggtttgctc agcatcttct aacttccctt ggtgatgtgg
    20341 atttttcgaa tggtctgcta ccactgccat ataaaggcta tctagtttag aaagtgccat
    20401 tgaaaaactc ctttgtcttt tgtagggcat cgactagttt gtcgcaatct gccttggtat
    20461 tgtagatata aaaacttgca cgagctgttg ctgggacttc caaatactga agcaagggtt
    20521 gcgcacaatg gtgaccagca cgaacagcca ctccttcata atccagagcc gtcgcaagat
    20581 cgtgaggatg gagatcacct aggttaaagg caataacacc cgaacgttga gccaaatcct
    20641 gagaaccgta aatggtcaat ccctcaattg cctgcagttt tggatagacg tacgcaatca
    20701 attcctgttc atgagcttca acggcatcca taccaatctt ttccagataa tcaactgcag
    20761 tcgcaagtcc aatagctcct gccatatttg gcgttccagc ctcaaatttc caaggcaatt
    20821 ccttccaact agcaaattgc tcgtagacaa aatcaatcat ctcgccgcca aattctactg
    20881 gagacatttg ctcaagatac ttttctttgc cgtaaaggac accgatacca gtcggaccag
    20941 ccatcttgtg acccgaaaag gcgaaaaagt ccagatccaa gtcctggaca tcaatcttca
    21001 tatgaggtgt agattgagca ccatccacta ccataattgc cccaacttgg tgggctaatt
    21061 gagtgatttc cttgatcgga ttgaccacac caagaacatt ggaggcatga gctagggaaa
    21121 caaatttaac cttatcagtc aatttagctc gcaaatcctc catatccaag gcaccgtctt
    21181 taagatagac atagacaagc tctgctccag tctttcgaca agcttcctgc catggaatga
    21241 tattagaatg gtgttccatt actgaaatca agacctggtc tccctcagtg agaatttcct
    21301 cagcaaagcg tgccacccag ttaaggctgg ttgtcgttcc tctggtaaag agaacttcct
    21361 ttgtagagcc tgcattaata aacttacgaa tggtttcacg agcagcttca taagaagctg
    21421 tcgctcgttc cgctaaggta tggacaccac ggtgaacatt ggcattgtcc tgctcatagt
    21481 agctgttaat agctttcaga actactagtg gtttttgtgt cgtcgcagca ttgtccagat
    21541 agaccagagg ttcatcattg acaatctgat ctaaaattgg aaaatccttg cgaatcgctt
    21601 ctacatctaa cataggctgc cccttagcgt tttgacaatt tctcttcgat agttgcaatc
    21661 atttcatcac gaacttcctt gactggaatc tccacgataa cagatccaag gaaaccacga
    21721 acaaccaaac gctctgcagt tgccttatcc aatccacgac tcatgaggta atacatgtct
    21781 tctggatcta cctgaccaat agaggctgca tgtcctgcag ttacgtcatt ttcatcaatc
    21841 aaaagaattg ggttagcatc tgaacgcgct tggtctgaaa gcataagaac acggctctct
    21901 tgttgcgcat ctgctccctt agcacccttg atgatgtggc cgataccatt gaaagtcaaa
    21961 gttgcttttt caaggataac cccatgttgt aggatatttc cgatagagtt gcagccatag
    22021 ttagttacac gagtatcaat cccttgtacc tgacgaccac ttgaaagagc tacaaccttc
    22081 aggtcagcat ggctaccatt accaatcaag tcactatcaa aatcagcaac gacatttcct
    22141 tcgttcatga caccgatagc ccagtcaata cttgcatcgt cgcctaattt accacgacgg
    22201 ctaatgtagg cagtgacgtt ttcacctaga cggtcgatag cagcaaactt gacttgcgca
    22261 ccagaacgtg caatcacttc cactgtgata ttggcagttg ctttgtcact tccttcaccg
    22321 cgtgactcta aacgctccag ataactaatc ttagaatttt taccagcgat aatcataata
    22381 tgcttgttaa acggcacatt gctatcgcta tcttggtaga aaattccttc aattggctct
    22441 gtgatttcta cgttatctgg aatatagagt acagcaccac tgttaaagta agctgtgtgg
    22501 taagccgcca acttgtcatc atcatactta acagatgaca tgaagaattc ttcgatcagc
    22561 tctggaattt cttctaaagc tgagtgaaag tctgtgaaga caacaccctg ttcagctaac
    22621 tcaactggag tttgttcgaa aacagtttga gttcctactt gcaccaactt caagtgatga
    22681 tctaaagctg tgaaatctgg aacatttgct gatggctcat tttctgtaat cgttccatca
    22741 cccagattcc aacggtggaa tttgacacgc tcaataactg gtaattccaa agtctcaatc
    22801 ttgtcaaaag ctttttgacg gagatcagcc aaccagcttg gttcagcgtg catttctgaa
    22861 aaaagtttaa tattttctct agtcatttac ttctcctaaa agatacgagg gaattacaat
    22921 tcttccttgt agtcgtagcc aagttcttca gctaattttg cgtatccttc acgttccaaa
    22981 cgcgcagcca attctggacc accagaaagg acaacacgac cttccatcat cacgtgtacc
    23041 acatcaggtg tgatatagtt caaaagacgt tggtagtgag tgatgatcat agcaccaaaa
    23101 ccttcaccac gcatggcatt gacaccttta gacacaactt taagagcgtc aatatcaaga
    23161 cctgagtcaa tctcgtccaa aagagcaaat gttggctcca acatcaaaag ttgaagaatt
    23221 tcattgcgtt ttttctcacc accagagaag ccttcgttga ggtaacgctc tgccatttct
    23281 tctttcatgt tgagcaattc cattttttca tctagcttag taataaactc acgaactgaa
    23341 atcttctcat catcttcttt acccgcattc atagcggcac gaagaaactc agcattggta
    23401 attccaggga tttctgatgg gtattgcata gcaaggaaaa gtcccatacg cgcacgctca
    23461 tccacttcca actcaaggat gtttacgcca tcaaacaaaa cttcaccttt agttacttca
    23521 tagtttggat ttcccatgat agcggcagaa agagtcgatt tacctgtacc atttggtccc
    23581 atgatagcgg caatttctcc tgttttcagg gtcaggttaa ccccttttaa aatttctttt
    23641 ccttcaatct caacgtgaag atctttgatc tctaatactg acatgatagt tcctttcttt
    23701 ttcaaaactt ttacagtact tactagaaaa acgtctgatt tccccagaaa tagagcaaaa
    23761 attctataaa tatacttttc tagtataaca aaaaaaagcc taaaaggctt tgattttgtc
    23821 tggaagctga gggctagtct ttcctattaa aatgctgatc gatgacatca acgattttgc
    23881 ccatcacata actgactcgg aaatttctaa agagtaaaat tgcccaaaag gctgccataa
    23941 tatagcgacc agtcatccag gcttcattga aaaaataggt ctcagcagct gtaaatagcg
    24001 ccataataat aaattgttgt ttattcataa acttattgta tcatgaaatc tttctttagt
    24061 cttcctctac cttcacttta tcagccaaaa attcaaatcc ttctggaatc aggctttctt
    24121 ctacttcttt ttcagtttga gaagatttgg ctttggctga aaaggctgcg cgaacttctt
    24181 tccattcctc catggaaata gctaaaatct caggtgaaaa acctgccgcc tgactgagga
    24241 tattaccaaa catggtattg agattgtctc gtttcatagt ttgaccagca ttgaagttag
    24301 actcaaaagc aagaatagca tggtgttcat tggcagcaac cggttgagaa ccaactagca
    24361 gagccttgtc cggcccacct agactttcaa ttacctctcc ccaggcattc tgcaaacgaa
    24421 ttagattttg acgtgctaaa tcaggatttt cgacggcctc ttgtaagata gattgcactt
    24481 tattgcgatc gacacgatag actgttttgc ccgtagctgg tcgactagga gctggtgcaa
    24541 cttgtttagg aaccgcacct gcattagaaa gctcttgttt gagacgggca acttcctgtc
    24601 tcagcgtagc aatttcattt tcaaccgctc ctgatagagc tggttcgggc ttgatttccg
    24661 ccaaacggac ggtcatcatt tcagcataaa tcttgggctg caaactagac ttaatatctg
    24721 ctaaattcac tgttgctaag cgaatcattt caaacagatt tttttgagga agtgccaaat
    24781 tttctacaaa gactgaacta tgatgagtat tttctccccc tgtttgaaca attaacaagt
    24841 ctcttaaata gtgcaaaaga tcggtcacaa aacgagtcat gctcttacca ttgtcaaaaa
    24901 gaagattcaa gcaagacaaa gctttgggaa catcctgttg agacaaggcc gccacataat
    24961 catccaaggc tgataggcta atggtgccag taatttcttc agagatagca gtcgtcagct
    25021 catttccctg tgtcaaactc agggcttgat ccaaaataga caaggcgtcc cgcattccac
    25081 cttccgcccg tctggcaatg atttccacag cctctggttc agaactgata ttttcttttt
    25141 ctaagatata gtgaatatgt tccttaatat cctgtgtctt aattgattta aactcaaaac
    25201 gttgcacacg ggatagaata gtagcaggaa tcttgtgcaa ttcagtagtg gccaaaataa
    25261 agactacatt ctgtgttggt tcttccagcg tctttaggag ggcattaaaa gcccctgtag
    25321 acagcatgtg aacctcatct atgatataaa ccttataacg agcaaggcta ggcgcatagg
    25381 tagatttatc acgaatttcg cgaatttcat ctaccccatt attagaagct gcatccattt
    25441 caatgacatc ttctaaacta ccgtccgtca ctgcttgaca aatatagcag ttattgcaag
    25501 gttcgccacc cacttgattg ggacagttca tagccttggc aaagatttta gcaacactgg
    25561 tttttcccgt tccacgagga ccagaaaaaa gataagcgtg acttattttc tcttgctcca
    25621 ccgcttgttt aagagtctta gccacaactt cttgaccaac taactgggag aagttttgac
    25681 ttctatattt tcgataaagt gcttgataca ttaagatttt tcctcaaaca tcgtaaagtc
    25741 ccatgctgtc ttttcaagca aaatagcgac aaattgttcc aaataatctc gatccatagc
    25801 atcgtaatcc tcaatctctg aagaatccag atccagaact ccaagtaact gaccattctt
    25861 catcatcggc accacaattt cacttttagc tagactatca caagaaatat agttgagata
    25921 ggtcgtcaca tctccaacaa taacagtttc ctgaaagtga gctgcctcac cacaaacacc
    25981 cttgcctagt gcaatacgga tgcaggaaac acctccttgg aaggggccta aaaccaattc
    26041 ctttccatcg aacaaataaa agcctgcaaa tacggtatta ggaaaacgtg attttatgag
    26101 agcactggcg ttggaaagat tagccaaaac attggtttcg ccttccaata ggaaggacaa
    26161 ttcttcattt aacatttgat aacgtgattg tttttctgat tttaacatag aactattata
    26221 tcaaaaaagg agcagagaca aaagaaaaat cccttgttta gtaaacaaag gattttgggc
    26281 tctataatat ttgtagtggg taaatcccct atggatatta tggagcctat ttttgtgtag
    26341 aaaaaaagtc ccatatgacc tataatgaaa agcgacaaaa caactcatta gaaagaatca
    26401 tatggaa
//
LOCUS       DAVEHY010000029        26293 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVEHY010000029 DAVEHY010000000
VERSION     DAVEHY010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.029"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(1..936)
                     /locus_tag="VUZ44_001503"
                     /pseudo
     CDS             complement(1..936)
                     /locus_tag="VUZ44_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1484..4042
                     /locus_tag="VUZ44_001504"
     CDS             1484..4042
                     /locus_tag="VUZ44_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU0320393.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            4342..5181
                     /locus_tag="VUZ44_001505"
     CDS             4342..5181
                     /locus_tag="VUZ44_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU0320394.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            5199..6410
                     /locus_tag="VUZ44_001506"
     CDS             5199..6410
                     /locus_tag="VUZ44_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU0320395.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGSNLAQGAASMAVALKSKNNNTKQIAFAAGFSALLAGITEPALYG
                     VTLKYKKPLYAAMIGGGLAGLFAGLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALI
                     VAVISVVITFVLAYIFGIDEEESSSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTF
                     SDKLIGDGVAIIPSEGKVYAPFDGKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELK
                     GQGFISHVEEGDRVFKNQLIFEMDLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQT
                     IEHSKELLVIL"
     gene            6423..7838
                     /locus_tag="VUZ44_001507"
     CDS             6423..7838
                     /locus_tag="VUZ44_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU0320396.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            8430..9476
                     /gene="pheS"
                     /locus_tag="VUZ44_001508"
     CDS             8430..9476
                     /gene="pheS"
                     /locus_tag="VUZ44_001508"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU0320397.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            9476..9985
                     /locus_tag="VUZ44_001509"
     CDS             9476..9985
                     /locus_tag="VUZ44_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320398.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            10062..12464
                     /locus_tag="VUZ44_001510"
     CDS             10062..12464
                     /locus_tag="VUZ44_001510"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU0320399.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(12532..13533)
                     /locus_tag="VUZ44_001511"
     CDS             complement(12532..13533)
                     /locus_tag="VUZ44_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU0320400.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            13689..14135
                     /locus_tag="VUZ44_001512"
                     /pseudo
     CDS             13689..14135
                     /locus_tag="VUZ44_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            14261..14527
                     /locus_tag="VUZ44_001513"
     CDS             14261..14527
                     /locus_tag="VUZ44_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0320401.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            14788..17037
                     /gene="metE"
                     /locus_tag="VUZ44_001514"
     CDS             14788..17037
                     /gene="metE"
                     /locus_tag="VUZ44_001514"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU0320402.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            17101..17967
                     /gene="metF"
                     /locus_tag="VUZ44_001515"
     CDS             17101..17967
                     /gene="metF"
                     /locus_tag="VUZ44_001515"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU0320403.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            18652..20865
                     /gene="pnp"
                     /locus_tag="VUZ44_001516"
     CDS             18652..20865
                     /gene="pnp"
                     /locus_tag="VUZ44_001516"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU0320404.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEVLLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            20881..21498
                     /gene="cysE"
                     /locus_tag="VUZ44_001517"
     CDS             20881..21498
                     /gene="cysE"
                     /locus_tag="VUZ44_001517"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU0320405.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            21510..22394
                     /locus_tag="VUZ44_001518"
     CDS             21510..22394
                     /locus_tag="VUZ44_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320406.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            22481..23824
                     /locus_tag="VUZ44_001519"
     CDS             22481..23824
                     /locus_tag="VUZ44_001519"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU0320407.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            23817..24203
                     /locus_tag="VUZ44_001520"
     CDS             23817..24203
                     /locus_tag="VUZ44_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU0320408.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            24207..25091
                     /locus_tag="VUZ44_001521"
     CDS             24207..25091
                     /locus_tag="VUZ44_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU0320409.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            25228..25683
                     /locus_tag="VUZ44_001522"
     CDS             25228..25683
                     /locus_tag="VUZ44_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320410.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            25680..25826
                     /locus_tag="VUZ44_001523"
     CDS             25680..25826
                     /locus_tag="VUZ44_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320411.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            25969..26139
                     /locus_tag="VUZ44_001524"
                     /pseudo
     CDS             25969..26139
                     /locus_tag="VUZ44_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         8131 a         4642 c         5791 g         7729 t
ORIGIN      
        1 aaatttctcc ggttccttat tctgaaagtg aaacagcaag agttgataga gctgatagtg
       61 atgtttcaag tcttgtgaat agctcaaaag cttgtctaaa atctctttat tggttaaatg
      121 catacgaaaa gtagggcgat aaaaatgttt atcgctgagt ttacggctat cctgttgaat
      181 gagtttccag tagcgcttga tagccttgta ttcatgggat tttcgatgaa actgattcat
      241 gatttggaca cgcacacgac tcatagcacg gctaagatgt tgtacaatat gaaagcgatc
      301 aagaacgatt ttagcattcg ggagtgaaac agtctgggag actgtttcag cctgagccta
      361 gaaatttgaa agcgaagctg tttagctaag tcatagtaag gactaaacat atccatagta
      421 ataattttga cgcgacatcg gacggctcta tcatatttaa gaaagtgatc tcggatgaca
      481 gcttgtgttc taccctcaag aacagtgatg atatcgagct tttcaaaatc ttgcgcaata
      541 aagctcatct ccatctcccg attgaaacag tcactccccg gactgtttca acgtcccaag
      601 acataatctt aggcagattt ctaaaattac actcaaagtg gaagtcattg agctttcgaa
      661 tgacagttga agttgaaatg gccagctgat gggcaatatc ggtcatagaa atcttttcaa
      721 ttaacttttg cgcaatcttt tggttgataa tacgaggaat ttggtgattt ttcttgacga
      781 tagaagtttc agcgaccatc attttcaagc aatgatagca cttaaaacga cgttttctaa
      841 ggagaattct agtaggcata ccagtcgttt caaggtaagg aattttatag ggtctttaat
      901 gtctagtaat tttgtgataa aatgtaattg ttccatatga ttctttctaa tgagttgttt
      961 tgtcgctttt cattatagat cttatgggac tttttttcta cccaaaatag gctccataat
     1021 atccataggg aatttaccca ctacaaatat tatagagccc aaagttttag gtcgcttgat
     1081 aatatgcgtt ttttgaattt tatagactgc tcgtttaaac tctatttact tcgtaccttc
     1141 tggagcgaga cggaatatta gtcacataca aaatgagtac tattaggatt ttattttcat
     1201 gtacaatttc agccagtctt gttataatca gcctatagga atcaaggagg tgactcttat
     1261 ggctgttttt gtgtctttgg atggaattgt ggtagaagtc cttgatgtct tttcttcttt
     1321 taatggggat agtgagtttt tcttgtgtat agcattttga atctggaata ggacgccatg
     1381 actgctaaaa gatttctata aattaatttg attttcctaa tcaatttgtt catatcttat
     1441 ttcattccac tataaacgtc ttaaagacaa gagtcagttt gttatggaac gctctcagtt
     1501 cgaggagatg ttccaacttc aaagtagtcg cttgacgacg caagaaaaat tacaattgtt
     1561 tacctctgtg tttgctggcc gttatgatgt ttatgctaag aattttatca atgaacaagg
     1621 gaaaattcag tattttcctt cctatgatta tggttggaag cagttgccac ctgaaaaacg
     1681 gagtttccag acattgacga actccgtttt gaaatctcat tttcgtgggg aggcagctat
     1741 cggtatcttt cctatgcact tagatgatag ctgttatttt ttggtactgg atttggatga
     1801 aggagattgg aaagaagctg gtttaaccat tcgaagaata gccagggaac gccagatgga
     1861 agcccattta gagatttctc gttcgggtta cggactccat atttggttct tctttgagga
     1921 agcgattctg agtcgaaagg ctcgcctgtt tggaaagaaa ctattagaat tggctatgca
     1981 ggaaagtatg caactgtcct ttgattcttt tgatcgcatg tttccaaatc aggatgttct
     2041 tcctaaaggt ggatttgata atttaatttc ccttcctttt caaggagaag cttatcatca
     2101 agggcgaacg gtctttgtgg atgaacagtt tcagccttat gaagatcaat ggaggtatct
     2161 acaagaaatt cagaagattt caactgctaa agtggcactg ttaatccaag aggagttagg
     2221 caagcaagaa ttggacaagg agttgaagat cgtcttatcc aatatgatcc aacttgaaaa
     2281 atcgtctgtg acacccaaga cactgttttt cttgaaaaat atggcttcat tttctaatcc
     2341 cgaattttat ttaaagcagg ctatgcgaca gccaacctat caaattcctg agagaatgta
     2401 tttatttgga gaatccgatc attatttatg gttgccaaga ggtttgctgt atccattgca
     2461 agataaattt aagcaggtat ctgtggaaga taggagaaag gtacaaaggt ctattagcgt
     2521 ggaatttaag ggagaactca cttttgagca agagttagcc ctgtcagata tgacttctaa
     2581 agaaaatggt ttacttcatg cggagactgg ttttgggaag accgttttag gtgctgctct
     2641 tatctctgaa cggaaaacaa aaacaattat tctagtccat aataagcaac tcttagacca
     2701 atggctagat cgcttaaact gctttttgac tttcgaagag gaggaggcta tccgttatac
     2761 ggcatcaggt cgtgaaaagg taatcggcta tgttggacag tacggtggga ctaagaaatg
     2821 gctgagtaaa ctggttgatg tcgttatgat tcaatctcta tttaagttgg aaaatagtca
     2881 aagtcttttg gatgagtatg agatgatgat tgtggatgag tgtcatcatg tctctgcctt
     2941 gatgtttgaa aaagttgttg ctcagtttag agggaagtat ctttacggtt tgacggctac
     3001 gcctgagcgt aagaatggtc atgagcctat tgtttttcag agaattggtg agatactcca
     3061 tactgctgat aagagggaaa cggattttaa acggcaattg caattaagat tcacttcttt
     3121 tggtcatttg gagattgaaa agaccaaagc aagtaatttt atacagctca gtgattggat
     3181 tgctacagac tcagcgagga atcagttgat tctcaaggat attctagccc aagtggcaga
     3241 aggacggaat atcttggttt tagttaatcg aattcaacag atagatgtct ttgaaaagtt
     3301 attgaaagag aaagaggttg atggctgtta cattattagc ggaaaaacca aagtccgaga
     3361 aagaacgagt ttactggaga cgttagaaca gttagataaa gggtttgttt tgttgtctac
     3421 tggaaaatac attggcgaag gttttgactt acctcagttg gacacgctta tcttggcagc
     3481 acccttttct tggaaaaata atttaattca gtatgcaggt cggattcata gaaactacaa
     3541 ggataagtct ttggtgcgta ttttcgatta tgtggatatt catgttcctt atttagaaaa
     3601 gatgtttcag aaacgacaag tagcttatcg aaagatggat tatcgtgtca tcgagggtga
     3661 ggagaaacaa ttcgtttatg ttgatagtag atatgagaag gtgttgagag aggacttagc
     3721 aggggaaaga caggaatgtc tgcttatttt accttatgtg caccagacaa aactgatgaa
     3781 ttttctaaaa gaatttagga ttagtcaaat tgagatatgt ataccagaga cggttgcaaa
     3841 taaagcatgg ctagaccagt tgaagagcca gaaaattaaa gtgtctttta ctcaatcaaa
     3901 aatagtaacg cctattcttt tggtgaataa gactattgtt tggtatggtg caatgccatt
     3961 attagggaag gtagatgaga tgaccatatt acgtttggaa tcagctagta tagtttctga
     4021 actagtggca ggtttacgat agagaaaatt tttaaaaatt tctatgtatg attttcattt
     4081 ctttagtgag actgttgcca ttatcacatt cgaatcacac aaaataaaaa aatttttata
     4141 agtacttgac aaatagattg aaatatcata aaataaaaac ggttacagag ttattaatta
     4201 tttaagcttc atgtcaccat taaaaattga aataaaagga tgttatcact aatacaagtg
     4261 agcaggaacc tatttaatca catcagaaga agtttcttga tgtttttaag taggttcctt
     4321 ttattttaaa agggaaattt tatgatcata aaacgaatac taaaccacaa tgccgtaatt
     4381 gcgcaaagta aaaaagatat cgatattctt ctttttggaa ggggaatagc ttttggaaga
     4441 aaaactggag ataaagtaaa tccaattgat attgagaaaa gtttttttct caaaaataga
     4501 gataatatga cccgttttac agagatgttt attaacgttc ctttggagtt ggtgtacatc
     4561 accgaaaaaa taattaacct aggtaaaata acattgggta ataattttga tgaaattatc
     4621 tatattaatt taacggatca tatttcttcg agcatagaac gttataaaga agggattatt
     4681 atttcgaatc ccctacgctg ggaaatatcg aaatattata aagaagaatt tgaacttggg
     4741 aaaagggctt tacaaataat aaaaaaagag ttaggtattg aacttccaat tgacgaagct
     4801 gcattcatag cgctacattt tgttaatgct aatttagaaa ataattttca agagtcgtat
     4861 aaaatcactg aaataattat gggaattgag aaaatcattc aagatttcta ttgtactgag
     4921 tttaaccaag attctattga ttattataga ttcataactc atataaaatt atttgcccat
     4981 cgcttggttg aaaatacaac ttattgtgac gatgatgatg aagacttgtt agcattaatg
     5041 aaaaataaat atcctagaga atatgaatgt ggtgaacagg tggcaatgtt tatacaaacg
     5101 gagtacaatt atttgctgac ttctagtgaa ttagtttatt tgatggctca tattcgtcgc
     5161 ttaacaaaaa atttagatta atagaatagg agaataccat gagttataaa gatacggtac
     5221 aaaaaatcct cgatgtaatt ggaggtgaaa aaaatgtcaa tagagttacc cattgtgtaa
     5281 cacgtttaag attagaatta aaagatgaaa atttagtcaa tgatgatgat gtgaagaaga
     5341 taccaggtgt aataggtatt atgaaaaaga atggacaata tcaaattata cttggtaatg
     5401 atgtagctaa ttattataaa gaattcgtta aacttggcaa ttttgaatcc gattcagttg
     5461 ttcaagggca caaagggaat attttagaaa gaatcattga gtatatcgct ggttccatga
     5521 ctccaatcat tccagcaatg ttagggtcaa acttagctca aggggctgct tcgatggctg
     5581 ttgcattaaa gagtaaaaat aataatacaa aacaaattgc ttttgcagca ggtttctcag
     5641 ccttacttgc agggattacc gaacctgcat tatatggtgt gactttaaaa tataaaaaac
     5701 cgctttatgc agctatgatt ggtggtggat tagcgggatt atttgcaggt cttactagtg
     5761 ttaaagcgta tctatttgct gtcccatctt tgatagcgtt gcctcaattt atttattctg
     5821 atgtgccatc aaatattgta aatgctttaa ttgtggcggt tatttcggtt gttattacct
     5881 ttgtattagc ttatatattt ggaatcgatg aagaagagag ttctagcaat ttagaagtta
     5941 aagctggagt ttcaaataaa aaaatgatat tttctcctat atcaggagaa atcattccgt
     6001 taagcgatgt ccaggataaa acattttcag ataaactaat tggagacgga gtagcgatta
     6061 ttccaagtga aggtaaggtt tatgcaccat ttgatgggaa aattacaaat atttttccga
     6121 ctaagcacgc aattggattg aagagtgatg agggtgttga gttactaatt catattggat
     6181 tagatactgt tgagctaaaa ggtcaaggtt ttattagtca tgtagaagaa ggagacagag
     6241 ttttcaaaaa tcagttgatt tttgaaatgg acttgaattt aatcaagact aaaggctacg
     6301 aaacagttac accagtaatt gtaacgaata ccaatgattt tctagatgta ttagtattac
     6361 ctaataatca gacaatcgag cattctaagg aattactggt aatattataa tggaggaaag
     6421 ttatgaccat ttttccagat gattttcttt ggggtggagc tgttgcagct aatcaagtag
     6481 agggagcata taatgaagat ggtaagggct tatcagttca ggatgtgtta cccaaaggtg
     6541 gattaggaga agcaacagaa aatcctacag aagataactt aaaattgata ggtattgatt
     6601 tttatcataa atataaggaa gatatatcct tgttttctga aatgggcttt aatgtttttc
     6661 gtacttctat tgcatggagt agaatttttc caaaaggaga tgaggaagaa cctaacgaag
     6721 ctgggttgaa atattatgat gaattgtttg atgaactaca tgctcacggg atagaaccac
     6781 ttgtaactct ttcacactat gagactccat tatatttagc aagaaaatat catggatgga
     6841 ttgataggag aatgattcat ttttatgaaa aatttgctcg aacagtttta gaaaggtata
     6901 aagataaagt taaatattgg cttacattta acgaagtaaa ctctgttttg gaattaccgt
     6961 ttactagtgg aggaatagat atacctaagg agaatctttc gaaacaagaa ttatatcaag
     7021 ctatacatca tgaattagtc gcctcgagtt tggttacaaa aattgctcgt gagattaatt
     7081 cagagtttaa ggtggggtgt atggtattag ctatgccagc ttatccaatg actccaaatc
     7141 caaaagatgt atgggcgact catgagtatg agaatctaaa ttatctattt tcagatgtgc
     7201 atgttagagg ttattatccg aattatgcaa aaagatattt taaggaaaat gacattaaca
     7261 tagagtttgc agctgaagat gcagagttat taaaaaatta tactgtagat tttttatcct
     7321 ttagctatta catgagtgtg actcaatctg ctcttccaac acagtataat tcaggagaag
     7381 ggaatattat tggtggttta gtaaatcctt atttagagtc ttctgagtgg ggatggcaaa
     7441 ttgatccaat tggactacgt ataattttaa atagatatta tgaccgttat caaattccat
     7501 tatttatagt ggaaaacgga ttaggtgcta aagatcaact aataaaagat gaatttaata
     7561 acttaacagt ccaagatgat tatagaattc agtatatgaa agaacattta ttgcaagtag
     7621 ctgaagctct acaagatggt gtggaaatta tgggctatac gtcttgggga tgtattgact
     7681 gcgtttctat gtccactgca cagctttcta agaggtacgg tctcatttat gttgatcgaa
     7741 atgatgatgg aaatggcaca ttcaatcgat ataagaaaat gtcctttact tggtataaag
     7801 gagtgattga atcaaatgga gaatccttat tcaaatagtt tgtttattga tgattagata
     7861 ttatcacggt taaggcagca tctcattaaa tatgaaataa agaggtttgg aagacatcaa
     7921 attctaaacc tctttatttt atagggggat taattaattt aattttgtta cagagagccg
     7981 attataaata gttaacttag gatagattgg ttatatatag tagactgaat ctaaaatagt
     8041 acgaaacaat tgctaaaaca tttatagaaa ttaattttac tttcccaatc gatttgtttt
     8101 catcttattt caatccgcta taaagttaga taagaataag ctaacaagca gaagtaagat
     8161 aggtcttgca agaatggtaa aaatctgata aactaagtgg taattgaata gaaatctgaa
     8221 agactagtag cccaagggaa gtatatcagg gaggagagcc gtgactgcaa gctctctata
     8281 tgaaagctgg gtgaattcac ttgcgcatgg atttagaaat gaaggtctga cttgtcagat
     8341 gaaaacggat ggtaccgcgt gtcaacgctc cgagtggagt ttttggcatg tggttttctt
     8401 tttatctacg agagactgat ggaggaaata tgtcaactat tgaagaacaa ttaaaagcgc
     8461 ttcgcgaaga aacgctgact agcttgaagc agattactgc tggaaatgaa aaagagatgc
     8521 aagatttgcg tgtctctgtc cttggtaaaa agggttcgct cactgaaatc ctcaaaggga
     8581 tgaaagatgt ttctgctgag atgcgtccaa tcatcgggaa acacgtcaat gaagctcgtg
     8641 atgtcttgac agctgctttt gaagaaacag ctaagctctt ggaagaaaag aaagtcgcgg
     8701 ctcaactggc tagcgagagt atcgatgtga cgcttccagg tcgtccagtt gcgactggtc
     8761 accgtcacgt tttgacacaa accagtgaag aaatcgaaga tatcttcatc ggtatgggtt
     8821 atcaagtcgt ggatggtttt gaagtggagc aagactacta taactttgaa cgtatgaacc
     8881 ttccaaaaga ccacccagct cgtgatatgc aggatacttt ctatatcact gaagaaatct
     8941 tgctccgtac ccacacgtct ccagttcagg cgcgtgctat ggatgcccat gatttttcta
     9001 aaggtccttt gaagatgatc tcgccagggc gtgtcttccg tcgcgatacg gacgatgcga
     9061 cccacagtca ccaattccac caaatcgaag gcttggtagt tgggaaaaat atctctatgg
     9121 ctgatcttca aggaacgctt cagttgattg tccaaaaaat gtttggtgaa gagcgtcaaa
     9181 ttcgtttgcg tccatcttac ttcccattca cagagccatc tgttgaggtg gatgtttctt
     9241 gcttcaagtg tggtggagaa ggctgtaacg tatgtaagaa aacaggttgg atcgaaatta
     9301 tgggagccgg tatggttcac ccacgtgtcc ttgaaatgag tggtatcgat gcgactgtat
     9361 actctggttt tgcctttggt cttggacaag agcgtgtagc tatgctccgt tatggaatca
     9421 acgatatccg tggattctac caaggagatg tccgcttctc agaacagttt aaataatgat
     9481 tagaaaagta gaaatggcag atgttgaggt gttggctaaa attgccaaac aagcctttcg
     9541 tgaaaccttt gcgtatgata atacggaaga gcagttacag gaatactttg aagaggctta
     9601 tagtctgaaa actttgtcaa ctgagttggg aaatcctgac tctgaaacct atttcattat
     9661 gcatgaggag gagatagctg gttttctcaa agtcaactgg ggaagtgctc aaactgagag
     9721 agaattagag gacgcttttg aaattcaacg cctctatgtg ctacaaaaat tccaaggatt
     9781 tggactaggt aagcaactgt ttgaattcgc acttgaactt gctacaaaaa atagtttttc
     9841 ttgggcttgg ctaggtgttt gggagcataa tacaaaagct caagcgtttt ataatcgata
     9901 tggttttgaa aaatttagcc aacatcattt tatggttggt caaaaagtag atacggattg
     9961 gttactgaga aagaaattaa ggtaagaaga ggattcttct attgaaatga taggaaagga
    10021 aaagaaccag tgtggcaatg gtcattctgg agaactaaat tatgcttata tcttataaat
    10081 ggttaaaaga attggtggac attgatgtgc catcacaaga gttggctgaa aaaatgtcaa
    10141 ctacaggaat cgaggtagag ggtgtcgaat caccagctgc tggtctctca aaaattgtcg
    10201 tcggtgaggt cttgtcttgc gaagatgtgc cagagactca cctccatgtt tgtcaggtta
    10261 acgttggcga agaagagcgt cagatcgttt gtggtgcccc aaatgtgcgt gctgggatca
    10321 aggtcatggt ggctcttcca ggagctcgta tcgctgataa ctacaaaatc aaaaaaggaa
    10381 aaatccgtgg tttggagtca cttggaatga tctgttcact tggtgaattg ggaatttctg
    10441 actcagttgt gcctaaggaa ttcgcagatg gcatccaaat cttgcctgaa gatgccgtgc
    10501 caggtgagga agtcttttct tacctagact tggatgatga aatcatcgaa ctttccatca
    10561 caccaaaccg tgcagatgcc ctttctatgt gtggagtggc tcacgaagtg gcagccatct
    10621 atgacaaggc agtcaacttt aaagaattta ctctaacaga aactaatgaa gctgcggcag
    10681 atgccctttc tgtcagcatt gagacagaca aggcgcctta ctatgcagct cgtatcttgg
    10741 acaatgtaac catcgcacca agtccacaat ggttgcaaaa tcttctcatg aacgaaggaa
    10801 tccgtcccat caataacgta gtggacgtga ccaactacat cctgctctat tttggtcaac
    10861 caatgcatgc ctttgacttg gataactttg aagggactga catccgtgtg cgtgaagcgc
    10921 gtgctggtga aaaattggtg accttggacg gtgaagaacg tgacttggac gtgaatgacc
    10981 tagtcatcac tgtcgcagac aagccagtag cccttgcagg tgtcatgggt ggtcaagcaa
    11041 cagaaatctc tgaaaaatct agtcgtgttg tccttgaagc tgctgttttc aatggcaaat
    11101 ctatccgtaa gacaagtggt cgcctgaacc ttcgttctga gtcatcttct cgctttgaaa
    11161 aaggaattaa tgtggcaaca gttaatgaag cccttgatgc ggcagctagc ctgattgcgg
    11221 aacttgcagg tgcgacggtg cgtaagggca tcgtttcagc gggtgagctt gatacttcag
    11281 atgtagaagt ttcttcaacc cttgctgatg ttaatcgtgt cctcggaact gagctgtctt
    11341 atgctgatgt agaagacgtc ttccgtcgtc ttggctttgg tctttctgga aatgcagaca
    11401 gctttacagt cagagtccca cgtcgtcgtt gggatatcac aatcgaagct gacctctttg
    11461 aagaaattgc tcgtatctat ggttatgacc gcttgccaac tagtctacca aaagacgatg
    11521 gtacagcagg tgaattgaca gccacacaaa aactccgccg tcaagttcgt actattgctg
    11581 aaggagcagg tttgacagaa atcatcacct atactctaac aactcctgaa aaagcagttg
    11641 agtttacggc tcaaccaagt aaccttacgg aactcatgtg gccaatgact gtggatcgtt
    11701 cagtcctccg tcaaaatatg atttcaggta tccttgatac cgttgcctac aacgtggctc
    11761 gtaagaataa aaacttggcc ctttacgaga ttggaaaagt ctttgaacaa acaggtaatc
    11821 caaaagaaga acttccaaat gaaatcaaca gttttgcctt tgccttgaca ggcttggttg
    11881 ctgaaaaaga tttccaaaca gcagcagttc cagttgattt cttctatgct aagggaatcc
    11941 ttgaagccct atttactcgt ttgggactcc aagtaaccta tacagcaaca tctgaaatcg
    12001 ctagccttca tccaggtcgt acagccgtga tttcattcgg tgaccaagtt cttggtttcc
    12061 ttggccaagt gcatccagtc actgccaagg cttacgatat tccagaaacg tatgtggctg
    12121 agcttaacct ttcagctatc gaagctgcgc ttcagccagc gactccattt gtagaaatca
    12181 ccaaattccc ggcagtcagc cgtgacgttg cccttctcct caaggcagaa gtgactcatc
    12241 aagaagttgt agatgctatc caagctgccg gcgtgaaacg tttgacagat atcaaactct
    12301 ttgacgtctt ctcaggtgag aaattgggac ttggtatgaa gtcaatggct tatagcttga
    12361 ccttccaaaa tccagaagat agcttaacgg acgaagaagt cgcacgctat atggaaaaaa
    12421 tccaagcatc gctcgaagaa aaagtcaatg cagaagtgcg ttaaacgata gtatgataca
    12481 aattccccct ctagtttatg aacactagag gggtgatttt atataaaata attaaaatgt
    12541 gatttctgta aaaatacatc tatgatcaga gttttgaaaa cttacaatgt ctaaatcttt
    12601 aacatagtag tggtttttag gcaataaaat atgatctatt gttgcattaa aaagttttgg
    12661 actttggcta ttccaagttc ctctttcaaa aggtggcagt acatttaatg cgtccctatg
    12721 agagcttatt tttgcaagtg ctccatgacg catagttgca ttaaaatcac ctgcaataat
    12781 agcctttgga tattttgaag ccaattgatt atgaatgatg tttaagtctt gcttccagat
    12841 ttccattaaa cctggcagag gaggagcagt atgcaaggca atgatatctg gtatattttg
    12901 ttttctcgaa tgtaatacaa ttgtcccgaa ccgtgttgta tgaaaagttt tagcttctgt
    12961 atagaaacca taacttttct tgacaatcac agtcacagga gctattccac tattggtagg
    13021 tggagaagtg aaaatatcat agttggccat agaaagtcca acttgatgaa acaatagttt
    13081 gattctctgg ttttcttgct cacctctgat attggtagct agttcaggga atatagccat
    13141 atcggcgtca aaatggctaa aaattcgctc aatatgttgt gcttctattt gattagcgac
    13201 gttccaagtt actaatttta aggttttagt cttatttgat gcagaagaaa gggttttatc
    13261 tgttccgaat aatagtaata tgagcgatag taagagcaaa atgccagagt aaaaccgtat
    13321 ttgtttattt ttcttgtaaa aagataggga aaaaaatacg aaacttaaaa tagcagccat
    13381 agttgcagta gctaagggga aggcataaat ctgtgccaag ataggttggg tagatagcca
    13441 aatgttaaga ttagaagatg ggaaaaaaga ataagttata atagggatag aaaagagaat
    13501 gaccgaaagg gcagagagaa atgttttaat cattgtgtga gtacctcaat ttgcaatggt
    13561 tgctcggagc taatgtgact ttgtgacttt acttgattga tattcttttt cttgtcttcc
    13621 tcatagatta agtacaaccc aagtaaaaaa agtccaattt aagattgaaa tgattaaaag
    13681 gcacagaaat gcaagacaat tatactacaa aaggcaaaca tttgacaatc gatagccgtc
    13741 gcttaatcga acgatggaaa aaagaaggaa aatcaaatag agaaattgcc tctctacttg
    13801 gaaaagctcc tcaaactatc catactgaaa tcaagtatgg gacagtccga caatgtcttg
    13861 gaaaagggcg cttcaaagag atttattctg ccgactacgc tcaacagtct tatgaaaata
    13921 atcgcaagca ctcggtcaag aaatcaagct tgactaagaa actaaaggaa aagattctcc
    13981 actatcataa ccaaaaattt tcgcctgaaa tgatggtgat ggctaaaggg gttaacgtgg
    14041 gaatttcaac catttactat tggattcatc gtggaaaatt ggggttaagc aagcaggatc
    14101 tgctttatcc tagaaaagga aaagcgctta agaaataggc tagcaccaac tttaaacccg
    14161 ctggtcaatc tatcgaatca taattcgctc atttttttaa aaatacatag acgtaaaaaa
    14221 aagagggtta agtgatgaag aatagtgcta ttgggagtaa ttggaaggat gtccatctga
    14281 gctctttagc aaggaggaaa tccttgaaag tgatatgcga gtggctatca tgagcgagtt
    14341 gattgaggct aggtatgaac aaggaatcag tcagaaaaag ctggaagaag tcagtggaat
    14401 aagccagcct gtcatagcta ggatggagac aggagagagc agtcttcagt tggatacggt
    14461 cttaaaagtt ctaaccagtc taggaaagac actagcagtc gttccacttg aacaggggaa
    14521 aagttgacta gaatcagtta tagtcttttc taataacagg tcatagtcac ttataagaat
    14581 tactaataac atgttttagt attctaattg gaatatagct gtaaagtaag aattacaaag
    14641 gatttgagac gtttgcttca agtctttttc ttttgtccga aacagatata tagtttcaaa
    14701 ctatatcaaa ccctaatttt ttacaattat acagacgctt tcttttctgt taagatagtt
    14761 tcaacaacaa attttggagg acacatcatg tcaactacaa tcatcggttt ccctcgtttg
    14821 ggcgaattcc gtgaattaaa atttacaact gaaaaatact ttagaaaaga aatctcagaa
    14881 gaagaacttt tagcagcagc aaaagacttg cgtgctaaac actggaacat tgtcaaagaa
    14941 aaaggcatca ctgaaattcc atcaaatgac ttttctcact atgataactt cctagatgcg
    15001 gctttccttt tcaacgtggt gcctgcatcc gttcaaaact tggacttgtc tgaccttgag
    15061 cgctacttcg ctttgggacg tggttaccag ggagaaaaag gggacgttcg cgcccttcca
    15121 atgaagaaat ggttcaacac taactaccac tacatcgttc ctaaatttga aaaagacact
    15181 caagtaaaat tggctggtca caagattttc gatgagttcc aagaagcaaa agaacttgga
    15241 ttgaacactc gtcctgttct tgtaggtcca ttcactttcc ttcaattgtc agactttgaa
    15301 gaaggcgtga aagcagacga cttcgtagat agcttagtgg ttgcttacca agaagttttt
    15361 gctaaattgg ctgaacttgg tgcgactcgc atccaattgg atgaagcggc tcttgtaaaa
    15421 gacttgacag ctgaagaaaa agctctcttc ttgaaccttt acaacaaact cttggctgac
    15481 aaaaaaggtc ttgaagtctt gcttcaaact tatttcggtg atgttcgtga cgtatacgct
    15541 gaccttgtaa acttgccagt agatgctatc ggtcttgact ttgttgaagg taagaaaact
    15601 cttgaactcg ttaaaggtgg cttcccagct gacaagactc tctatgtagg tattgtcaat
    15661 ggtaaaaaca tctggcgcaa caactacgaa aagagcttgg ctgttcttga gcaaatccca
    15721 gctgaaaaca tcgttttgac aagctcttgc tcacttcttc atgtgccatt tacaactgct
    15781 aatgaagaat ttgaaccagc actcttgaac cactttgcct ttgcagttga aaaattggat
    15841 gaaatccgtg acttggatgc tatccgcaat ggtcaaggtt cagaagctct tgcagccaac
    15901 aaagaactct ttgcgactga gcgtgttggt gaaaatgctg aacttcgtgc gcgtatcgct
    15961 ggcttgacag acgcagacta cactcgtttg ccagcctttg cagaacgtga agctatccaa
    16021 gaagaagctt tcaaacttcc agctcttcca acaacaacga ttggttcatt ccctcaaaca
    16081 aaagaagttc gtgccaaacg tttggcttac cgtaaaggtg aattgtctca aaaagagtac
    16141 gatgctttcc ttgctgaaac gattgacgaa tggatcaagt ggcaagaaga tattgacttt
    16201 gatgtccttg ttcacggtga atttgagcgt aatgacatgg ttgagtactt cggtcaaaac
    16261 ttgtcaggat acctcttctc taaaaatgga tgggtacaat catacggtat gcgtggggta
    16321 aaaccaccaa tcatctgggg tgatgtcact cgtcttaacc ctatcactgt taaatggtct
    16381 agctatgcac aaagtcgtac aaacaaacct gttaaaggta tgttgactgg acctgttacc
    16441 atccttaact ggtcattccc acgtgaagac atctctatca aggattcaac tcttcaaatc
    16501 gcccttgcta tcaaggatga agtacttgac cttgaagctg ctggtgtgaa aatcatccaa
    16561 atcgacgagg ctgctcttcg tgaaaaattg ccactccgcc gtagcgactg gtacgaagac
    16621 taccttgact gggctattcc tgccttccgc ttggtacact caacagtagc gccagacaca
    16681 caaatccaca ctcacatgtg ttactcagaa tttacagata tcatcccagc tatcgataac
    16741 atggatgcag acgttatttc ctttgaagct agccgttcaa accttgaaat cttggacgaa
    16801 ctcaaagcga aaaacttcca aacagaagtg ggacctgggg tttacgatat ccactcacct
    16861 cgtgtaccaa atgaaggcga aatcgacaac acaatcgaag ccatccttgc taaagtgcca
    16921 agcaagaaag tttggatcaa ccctgactgt ggtttgaaaa cacgtggtat cccagaaaca
    16981 aaagaaagct tgatccgcct tgttgaagca gctaaagctg cgcgtgagaa attgtaagat
    17041 tggatttctc tccatacagt ggttgttcaa aaagaaatca actagaaaag gttattacat
    17101 atgtcacgcc aaacaccgtc actctcattt gaagtgttcc ctccaaaccc agccgtgggt
    17161 aatggtaaca ttatttcagc cttgcaggat atgcaggagt tggctcccca ttttatcagt
    17221 gtaactgcca gcaataataa atttaatatc aaggaaacga cggttcgttt ggctgacttt
    17281 atccaaaatg acttggcgat tccgaccatt gcccacttgc cagctattta tctaactaag
    17341 gacaaggttg ctgaaactat tgctgacttg gacaaagttg gggtgcagaa aatcttggct
    17401 cttcgtgggg atattattcc agacgtagaa ccacaaaagg atttccgcta tgcaaccgac
    17461 ttgattgagt ttatcaagga acaagcccct cactttgata ttattggagc ttgctatcca
    17521 gaagggcatc cagattcgcc aaatcagatt tcagatattc aaaatcttaa gaagaaagtg
    17581 gatgcaggct gttcgagcct cgtaactcag ctcttctttg ataatgagcg cttctatgat
    17641 tttcaggaca agtgtatttt ggctgggatt gatgttccca ttcatgcagg aattatgcca
    17701 attctgaatc gaaatcaggc tctccgactc ttgaagactt gtgagaatat ccatcttcca
    17761 cgcaaattta aagccatctt agacaagtat gagcatgacc ctgagtcgct cagagcagca
    17821 ggacttgcct atgcagtgga ccaaatcgtg gacttggtaa ctcaggatgt tgccggtgtg
    17881 catctctata cgatgaataa tgctgataca gcaaaataca tccatcaagc aacccatgcc
    17941 ttgtttaatc accagtctct aggataataa aagcaaacca ttcttctcag gtgaggggaa
    18001 tggttccttt ttaatggtaa agacctcact ttttaagaaa aatatgataa aataaattct
    18061 gtacgtactt gatacaaaga tgaaggtatt aaataataca atgcatttaa actgtaagat
    18121 ttaacgacac gagtgagtca aatcgatgtt atttgacgag agagttagta aagcatttag
    18181 ctaatcgccc gatagcgatt agcgtgaaag ctttagatac tttagtatta aacctttcta
    18241 atgatgtatc ttgaaaactg aacttgccta caactctgtg gaaaaagata aatctcccta
    18301 ggagcagtcg ctccgtcgtt cgatttccta ttttcctttg agttgcttga cggcttggta
    18361 tcttgatgac ttgaattttg gtctcatttc ttaggaaaaa agataagctt cctagcactc
    18421 gtcgagtgcg acgtcacctt cctatttttc tacagaaatg ttcggcaagc cgaaccgtcc
    18481 aaaatatctt gtgtaattga acacggccga aaagctgtgt aaaaaagata aactgtcttg
    18541 tcttcatcga agacttcgtc agtttcctat ttttactttg cttttgacgt ccttggtatc
    18601 ttgatctttg taggcaaggc gtataatttc atcaatccaa aggggattaa aatggcaaaa
    18661 caagtgtttc aaacgacttt tgcgggtcgt gagttaattg tagaaactgg tcaggttgct
    18721 aagcaagcaa atggctctgt tgtcgtacgt tacggtgagt caactgtctt gactgctgcc
    18781 gttatgtcta agaaaatggc aactggggat ttcttcccac tccaagtcaa ctacgaagaa
    18841 aaaatgtatg cggctgggaa gtttcctggt ggctttatga aacgtgaagg acgtccttca
    18901 acagatgcga ccttgacagc gcgtttgatt gaccgtccga ttcgtcctat gtttgcggaa
    18961 ggtttccgta atgaagtcca agtcatcaat acagtgcttt cttatgatga aaatgcatct
    19021 gcaccaatgg ctgctatgtt tggttcatct ttggcactgt ctatttcaga tattccattt
    19081 gacggaccaa ttgctggggt acaagtggga tatgtagatg gccaaatcat catcaaccca
    19141 agtcaagaac aagcagagca atctcttctt gaattgacag tagctggaac caagcacgct
    19201 atcaacatgg tagagtctgg tgccaaagaa ttgtcagaag aaatcatgtt ggaagtgctt
    19261 cttaaagggc acgaagctgt caaagaattg attgccttcc aagaagaaat cgttgctgct
    19321 gtcggtaaag aaaaagcaga agtggaattg cttcacgtgg atgctgaatt gcaagctgaa
    19381 atcattgcag cctacaacag tgacctccaa aaggcagttc aagtagaaga gaaattggcc
    19441 cgtgaagctg caactcaagc agtgaaagac caagtgactg ccgtttacga agaaaaatat
    19501 gcgaaccacg aagaatttga ccgtattatg cgtgatgtgg ctgaaatctt ggaacaaatg
    19561 gaacacgcag aagtgcgacg tttaattaca gaagacaagg tgcgtcctga tggtcgtaag
    19621 gtcgatgaaa tccgtccttt ggatgcggtt gttgacttcc ttcctcgtgt acatggttca
    19681 ggtctcttta ctcgtgggca aactcaagct ctttcagtct tgaccttggc tccgatggga
    19741 gaaactcaaa tcattgatgg tttggatcca gagtacaaga aacgctttat gcaccactat
    19801 aacttccctc aatattctgt aggggaaaca ggtcgttacg gtgcgccagg tcgtcgtgaa
    19861 atcggtcacg gtgcccttgg tgagcgtgct cttgctcaag tcttgccaag cttggaagaa
    19921 ttcccatacg ctatccgtct agtagcagaa gttttggaat caaacggttc ttcatctcaa
    19981 gcttctatct gtgcgggaac tcttgccctt atgactggtg gtgtgccaat caaggcgcca
    20041 gtagctggta ttgctatggg acttatctca gatggaaata actacacagt attgacagat
    20101 atccaaggtt tggaagatca ctttggagat atggacttca aggttgcagg tactcgtgat
    20161 gggattacag cccttcaaat ggatatcaag attcaaggga ttactgcaga aatcttgacg
    20221 gaggctcttg ctcaagccaa gaaagcgcgt tttgaaatcc ttgatgtcat tgaagcaacc
    20281 attccagaag ttcgtccaga attggctcca actgctccga aaattgatac gatcaagatt
    20341 gatgtggaca agattaagat tgtcatcggt aagggtggag aaaccatcga caagattatc
    20401 gctgaaacag gtgttaagat tgatatagac gaagaaggaa atgtgtctat ctactctagt
    20461 gaccaagatg ctattaaccg tgccaaagaa attattgctg gtttggttcg tgaagccaaa
    20521 gtggatgaag tttaccgtgc taaagtcgtt cgtatcgaga aatttggtgc ctttgttaac
    20581 ctctttgata agacagatgc ccttgttcat atctctgaga tggcttggac tcgtaccaat
    20641 cgtgtagagg atttggtaga aatcggggat gaagttgatg ttaaggttat caagattgat
    20701 gaaaaaggcc gtatcgatgc ctctatgaag gctcttctac ctcgtccgcc aaaacctgag
    20761 catgatgaaa aaggtgaaaa gtctgagcgc cctcaccgcc cacgtcatca caaggatcac
    20821 aaacctaaga aagaatttac agaaacacca aaagattcag agtaagaaaa ggagaaatgt
    20881 atggggtggt ggcacgaaac cattgatatc gtaaaagaaa atgatccagc ggcccgcacc
    20941 actttggagg ttttgctgac ttatccaggt gtcaaggcct tggcggccca ccgtctctcg
    21001 cattttctct ggaagtacga cttcaaactc ttagctcgta tgcacagtca gttttggcgc
    21061 ttttggactc agattgagat tcatccagga gcccagattg attcaggtgt ctttattgac
    21121 catggttctg gtctggtgat tggagagaca gcgattgttg aaaaaggcgt tcttctctat
    21181 cacggagtga ctctcggggg aacagggaaa gactgtggca aacgccatcc gactgtacga
    21241 aagggagccc tcatatcagc ccatgcccaa gttatcgggc ctgtggaaat tggtgaaaat
    21301 gccaaggtcg gtgctgcagc agttgtcgta gcagatgtac ctagtgatgt gacggttgtc
    21361 ggtattccgg ccaagattgt ccgtcttcat ggtaagaaag atgagcctgt tattcacgaa
    21421 gtcgaagaaa aacgggagta ttatgtcaat aaactcgagc aggctaaaga tgccagtcac
    21481 agatcgtctg gtttgtagag gatacctata tgattcaagc aagaaacaag ttaagccaag
    21541 aggagctatc tgaggcgaaa aaagtaatta actgttgcca aaactatgac ggtacctatc
    21601 gcgatcccta tctctctaac atgcttaatt ttgacccaaa catgcccgcc tttttccttt
    21661 attatgaaaa aggcaaactt gttggtttat taactgtcta tgcagatgac caagatgtag
    21721 aagtgacgat attggttcat ccaggtcatc gccgtcaggg gattgcgcgt gcattgttta
    21781 ctagttttga gagagaaaca gcttctttcc ccattcggtc agtcactttt cagacagaac
    21841 gtattttttt agagaatcat cctgactttg ccagtaactg gggactaatc gaggatgaag
    21901 agacagaaac ttggttaggt aaggatagaa gaccttatcc gttagcaaat gtttcccatc
    21961 ttgaagtttt gttagcagat agttcgtatc aggatcaaat tagtcaatta aaatttcagg
    22021 cattttcaga ggaacatgaa tcgagagaag ttgtggatag atatgtcgct gaagctctga
    22081 aggatccaga aagtcgctta tatattttgt taaaagacgg tcaggttatt gggacttgca
    22141 cggtagattt atcgactaat acgaattact tctacggttt agcaatatcg gaacctgaac
    22201 gtgggaaagg ctatggaagc tacttagcaa aatccctcgt caaccaacta attgagcaaa
    22261 atgacaagga atttcagatt gcagtggaag atagcaatgt aggtgccaaa cgtttgtatg
    22321 aaaaaattgg ctttgtcaaa cagacacagg tggtttatct gaatgagaaa ggagcaaggg
    22381 attccgaagt gtagagacat tcggactgaa atttacttga gctcttagtt tagtgatgaa
    22441 actaacagtt cttggatttt agctttcctg attatgattt atgattaaaa tctatgacac
    22501 catgtctcgt gatttgcgag aatttgtccc gattgaggac ggcaagatca agatgtatgt
    22561 ttgtgggcca accgtgtaca actatattca cgtgggaaac gcccgttcga cggtagcttt
    22621 tgatacgatt cgtcgctatt ttgagtaccg tgggtataag gttgcctata tttccaattt
    22681 tacagatgtg gatgataaga ttatcaaccg tgccagggaa gaaggcatca cacctcagga
    22741 ggttgcggat aagtacatcg ctgcctttcg tgaggatgtg acggccttag gcgtgaaacc
    22801 tgcgactcgc catccgcgtg tagtggagtt tatggcagac atcatccgtt ttgtggaaga
    22861 cttgatcgag aaaggctttg cctatgagag tcaaggggat gtctatttcc gtgtagaaaa
    22921 atcccacaac tatgctaaat tggctaataa aaccttggaa gatttggagc taggtgcttc
    22981 aggtcgtacc gatgaagaaa cggctcgtaa ggaaaatcct gtagactttg ctctatggaa
    23041 atcttccaaa ccaggtgaga tttcttggga tagtccttgg ggacctggac gtccgggttg
    23101 gcatattgag tgttcagtca tgtcgacaga gattttaggt gataccattg atatccacgg
    23161 tggtggagct gacctagagt ttccacacca caccaatgaa attgcccagt ctgaagctaa
    23221 aacaggcaag gcttttgcta actactggat gcacaatggc tttgtcaata tcgacaatgt
    23281 caaaatgtct aagtccttgg gtaacttcat tacggtacac gatgccctta aaactcttga
    23341 tgggcaagta cttcgtttct tctttgcgac ccagcactac cgtaagccta tcaacttcac
    23401 ggaaaaggca gttcgcgatg ccgagaccaa tctcaagtat ctgaagaata cttacgaaca
    23461 accatttaca ggaaacgtgg atgcccaaga gttacaaaac tttaaagata agtttgtagc
    23521 agctatggat gaagatttta atgctgccaa cggtatcaca gttgtctttg aaatggccaa
    23581 atggatcaac tcagggaact atgatgcaag tgtcaagcaa gctcttgcag atatgttaga
    23641 aatttttgga attgtctttg ttgaggaagt tttggatgca gagattgaag acttgattca
    23701 aaaacgccaa gaggcgcgtg ccaatcgtga ctttgcgaca gcagaccaaa tccgtgacca
    23761 attggttact caaggaatta agctccttga taccaaggat ggagtgaggt ggacacgtga
    23821 ttgatgtcaa tctcattaac gggattgcgc tagcctttga gggggatgcg gtgtattcta
    23881 tgtatattcg ccgtcacctc atcctcaaag gtatgaccaa acccaataaa ctccatcaag
    23941 aagcaactaa gtacgtgtca gccaaggctc aggctcgcct gattgctctc atgttggagg
    24001 agcaggtcct aacggaaaaa gaagaagaaa tctacaaacg tggccgcaat accaatagcc
    24061 acacaaaggc taaaaatgca gatgtcgtga cttatcgtat gtccacggga tttgaagcgg
    24121 ttatgggcta tctccatatg actgagaatc tggaacgtct tgagagtttg gtttcatggt
    24181 gcatccaaaa agtggagggc tagaacatga gggcaaaaga actacaagac tggtttcctg
    24241 aggctcggat ttcagaccaa ccagtagaga aagagggcta tctcacgctc cctttagctt
    24301 ctcagcagtg gattttgctg gaggaagctg ggctcagcga gcgtgaaaag cagttggttg
    24361 cccttttgac ccagcaggag caggctcgtt cgctaaaccc ttggtattcc tatctggttg
    24421 agggcaaggg acaggcaccg caagttttta aaaagattca gttggtttat tgccatcttt
    24481 cttattttca gcaggaaaat ctggcttctt ggctagatat gatgcggact ctttttccga
    24541 attgtcagac agtgctacag gtcggagctc aggattatgt tttcgtgctt caacaagaca
    24601 aatacacttc tgtaagagat attttaagtg atacgattga agcggttgag tatgactttg
    24661 gacttcgtct ttctatcatg ttgggtcagg tttggtctca gacgggacat caagccctat
    24721 cagacttaat caaagctgag cgggatttgt tcaagacatg gtggcgtcag ggtcaccaag
    24781 gtgttcatac tttttctcag ctctatcttt ggagtatggg agaaagactc gtggacttga
    24841 agccaatcaa ggaatgtcta caccagatga ttttggatca agatcagatt caggaaatca
    24901 ttctctctct ttgggaaaat agtgctgttc tcactaaaac agcccagcaa ctctatctgc
    24961 accgcaattc tctccaatac aagattgata aatgggaaga gttgacaggg cttcagttga
    25021 aagagttgac cgacctgacc ttgtgttatc aattgatttt aggttctttg tcaactatag
    25081 ttggtttgta aagaagttaa tatttggaga agaggattgc catcttctcc atttttatgt
    25141 gcagagttat agtggcttga tgctgggaaa gtacactgtg actgctaaaa cattcctaga
    25201 agctgctttg atttccctaa tctatttatg caaattttat gttattttac tataacagtt
    25261 gttgctaagc caaataatag tggggaagtt catttagacg taagcattga agataatcag
    25321 ggaggtagtg ggtataattt cagttctgtt tcaagtagct cacaaacagc taaatatgaa
    25381 ggaactgttt ataataacaa ttcatcatta tatataacga ttgataaaac gtctgatgca
    25441 acagctcttt tgaaattaaa gttgaataat gttgataatc aacctgctac tgaagttcct
    25501 agttcaggaa ttactgtaaa attaaatgct aaagataatg ctggaaactg gacaagtgct
    25561 tcgaataaaa aagaaataac agtaaaaatt gtttctgcta aaccgacata tccagacaaa
    25621 atcttagtga aaaatcctga taatataaaa gatacagaaa aaatgccatt attgaaaaat
    25681 tgaaagaggc aaataaaaat catccagcag gagctccaac ctttgctaaa ggtgaaggag
    25741 agcatgcaaa tgatattgta gcaacttatt cagatggtac aacttattat gtaccgttaa
    25801 atgatgtgac aaaatatgcg aggtagtggc tgtaccactc acttattcac ctccccgtga
    25861 tttgtagtag tgataggctt tctcactatt attataaaac aaaataaaga tcacaacact
    25921 ttttcattct gtgttgtgcc ttgagtgaaa cgaaaggaat gaattataaa tatgaaaagt
    25981 atagtcacta gcatagatga gcgcttgcgt actcgcctac gagtgattat ctggaagcaa
    26041 tggaagaaga aatcgagacg attatgggga ttgcttaagt taggggttcc taaatggata
    26101 gcagataagg tatctggctg gggcgaccac tatcaattat attaaaatga aataagaata
    26161 ggacgaatcg atcagggaag tcaaatcgat ttctaacaat attttagaag tagaggtata
    26221 ttattctagt ttcaatctac tatagtagct cagaagtcgg tacttaaacg tgctatatca
    26281 aaaccagtcc ttg
//
LOCUS       DAVEHY010000030        25567 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVEHY010000030 DAVEHY010000000
VERSION     DAVEHY010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25567
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.030"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(5..1660)
                     /gene="pavA"
                     /locus_tag="VUZ44_001525"
     CDS             complement(5..1660)
                     /gene="pavA"
                     /locus_tag="VUZ44_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU0320412.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            1765..2262
                     /gene="ybeY"
                     /locus_tag="VUZ44_001526"
     CDS             1765..2262
                     /gene="ybeY"
                     /locus_tag="VUZ44_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU0320413.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            2243..2638
                     /locus_tag="VUZ44_001527"
     CDS             2243..2638
                     /locus_tag="VUZ44_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU0320414.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            2655..3554
                     /gene="era"
                     /locus_tag="VUZ44_001528"
     CDS             2655..3554
                     /gene="era"
                     /locus_tag="VUZ44_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU0320415.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            3602..4426
                     /gene="mutM"
                     /locus_tag="VUZ44_001529"
     CDS             3602..4426
                     /gene="mutM"
                     /locus_tag="VUZ44_001529"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU0320416.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            4426..5031
                     /locus_tag="VUZ44_001530"
     CDS             4426..5031
                     /locus_tag="VUZ44_001530"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU0320417.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEAIVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5018..6217
                     /locus_tag="VUZ44_001531"
     CDS             5018..6217
                     /locus_tag="VUZ44_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU0320418.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILAFYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            6217..6366
                     /gene="rpmG"
                     /locus_tag="VUZ44_001532"
     CDS             6217..6366
                     /gene="rpmG"
                     /locus_tag="VUZ44_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU0320419.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            6406..6639
                     /gene="secG"
                     /locus_tag="VUZ44_001533"
     CDS             6406..6639
                     /gene="secG"
                     /locus_tag="VUZ44_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU0320420.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            6741..9095
                     /gene="rnr"
                     /locus_tag="VUZ44_001534"
     CDS             6741..9095
                     /gene="rnr"
                     /locus_tag="VUZ44_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU0320421.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKSFYKEVAKKGAKHGKGRGKGRRTK"
     gene            9058..9525
                     /gene="smpB"
                     /locus_tag="VUZ44_001535"
     CDS             9058..9525
                     /gene="smpB"
                     /locus_tag="VUZ44_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU0320422.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            9541..10401
                     /gene="tehB"
                     /locus_tag="VUZ44_001536"
     CDS             9541..10401
                     /gene="tehB"
                     /locus_tag="VUZ44_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU0320423.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            10474..11427
                     /gene="coiA"
                     /locus_tag="VUZ44_001537"
     CDS             10474..11427
                     /gene="coiA"
                     /locus_tag="VUZ44_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU0320424.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            11446..13248
                     /gene="pepF"
                     /locus_tag="VUZ44_001538"
     CDS             11446..13248
                     /gene="pepF"
                     /locus_tag="VUZ44_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU0320425.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            13250..13963
                     /locus_tag="VUZ44_001539"
     CDS             13250..13963
                     /locus_tag="VUZ44_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU0320426.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14030..14971
                     /gene="prsA"
                     /locus_tag="VUZ44_001540"
     CDS             14030..14971
                     /gene="prsA"
                     /locus_tag="VUZ44_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU0320427.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(15088..15429)
                     /locus_tag="VUZ44_001541"
                     /pseudo
     CDS             complement(15088..15429)
                     /locus_tag="VUZ44_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            15842..15937
                     /locus_tag="VUZ44_001542"
                     /pseudo
     CDS             15842..15937
                     /locus_tag="VUZ44_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16190..16810)
                     /locus_tag="VUZ44_001543"
     CDS             complement(16190..16810)
                     /locus_tag="VUZ44_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU0320428.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(16810..17292)
                     /locus_tag="VUZ44_001544"
     CDS             complement(16810..17292)
                     /locus_tag="VUZ44_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU0320429.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(17292..18134)
                     /locus_tag="VUZ44_001545"
     CDS             complement(17292..18134)
                     /locus_tag="VUZ44_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU0320430.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSH
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(18229..19017)
                     /locus_tag="VUZ44_001546"
     CDS             complement(18229..19017)
                     /locus_tag="VUZ44_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU0320431.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKAYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            19161..20540
                     /gene="glmU"
                     /locus_tag="VUZ44_001547"
     CDS             19161..20540
                     /gene="glmU"
                     /locus_tag="VUZ44_001547"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU0320432.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            20550..21095
                     /locus_tag="VUZ44_001548"
     CDS             20550..21095
                     /locus_tag="VUZ44_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU0320433.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            21107..21421
                     /locus_tag="VUZ44_001549"
     CDS             21107..21421
                     /locus_tag="VUZ44_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU0320434.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            21438..22130
                     /locus_tag="VUZ44_001550"
     CDS             21438..22130
                     /locus_tag="VUZ44_001550"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU0320435.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            22207..22698
                     /gene="rocS"
                     /locus_tag="VUZ44_001551"
     CDS             22207..22698
                     /gene="rocS"
                     /locus_tag="VUZ44_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU0320436.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            22796..23386
                     /locus_tag="VUZ44_001552"
     CDS             22796..23386
                     /locus_tag="VUZ44_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU0320437.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            23395..25158
                     /locus_tag="VUZ44_001553"
     CDS             23395..25158
                     /locus_tag="VUZ44_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU0320438.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            25372..>25567
                     /locus_tag="VUZ44_001554"
     CDS             25372..>25567
                     /locus_tag="VUZ44_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0320439.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRL"
BASE COUNT         7770 a         4674 c         5602 g         7521 t
ORIGIN      
        1 aaaatcagga ttttttcatg gatgcaattt ttttggagtc tggtgtgacg cggagggtct
       61 tttgtcctgt gtaagtgaca aagccgggtt ttccaccagt tggtttattg agttttttga
      121 cttcaatcat atctacctgc accagattcg acaggcgccc ttgagagaag taggcagcta
      181 actctgctgc gtctgtcttg actgcatcag atgggtcaag atttcctgag atgacaacat
      241 ggcttccagg aatgtcctta gcatggaacc aaagttcctc cttgcgggcc attttaaagg
      301 tcaattcctc attttgaaga ttgtttcgtc cgacatagat gatggttttg ccatcgcttg
      361 ctagatattg ttctagtttt ttgcgtttct ggattttctc ccgttgtctt ctgcggataa
      421 aacctgtttg aatcaattct tcacggattt cagcgatttc ttccagtcca gcttggttga
      481 ggacggtttc tacactttcc agatagagaa tagtggcttt ggtttcttca atcaaatcag
      541 tcaagtattt gacagcttct ttgagtttct gataccgttt aaaatagcgt tgggcattct
      601 ggttgggagt cagagcctta tcaagcgcaa tcatgatagg ttggttggta tagtagttgt
      661 ctaggataac ctggtcttgg tcgttaggca cttggtggag gaaggttgtc agcaattctc
      721 ctttttgacg aaattcttca gcgttgtctg tcgccagtaa ctctttttcc tgttttttga
      781 gtttgtgtcg gtttttctga agttcatttt caacacgacg aatcagttca ctggcctgct
      841 gtttgacgcg gtcgcgctca gccttatcct tatagtaggt gtccaacaaa tcagaaagat
      901 ttgcaaaagg ctctcccacc tgatttgcaa aaggaactgg actgaaggaa gtctcagtca
      961 agcatggctt ggtttcctga ttgaaaaaat ttcggaaagc ggaaagtttt tcactaacca
     1021 gtatcctttc caattcattt gccgtatcgc gtcccagacc ttgaaagagg ctttgaagat
     1081 tttttgctgt tagttcttgg gtttgcagga tttcaaagag cttttcatcc ttgatagtaa
     1141 aaggattgag agattctgta cttggcggag cgatataggt cgatcctgga agtaaggtgc
     1201 ggtagctatt ttgtgaaaaa ccgacgtgtt tgataacttc gaggatttta tgactgcttt
     1261 tatcgaccag tagaatatta ctgtgtttcc ccataatttc gataatcaag gtagcctgga
     1321 tatggtctcc aatctcgttt ttattggaaa ctgtcatttc cacaatacgg tcattttcca
     1381 cttgctcaat cgactcaatc agggccccct gcaaatactt tctcaaaacc atgataaagg
     1441 tagaaggttg ggctggattt tcaaaagtcg tttgggtcag ctgaatgcgt ccaaaaactg
     1501 gatgggcaga aaggagcagg cgatggcttt ggcgattgct gcggatttgc aagaccaact
     1561 cttgttcaaa aggctgattg attttctgga tgcgaccatt cactaattcg cttcgcaatt
     1621 cctcaactat gtggtgtaaa aaaaatccgt caaatgacat cgttctctcc ttgtgattgt
     1681 attccatagt attatatcaa aaaggtagaa taaaatcatg gaaatgtggt ataataaagc
     1741 caagtaaaga gaaacgagaa gcacatgtat attgaaatgg tagatgaaac tggtcaagtt
     1801 tcaaaagaaa tgttgcaaca aacccaagaa attttggaat ttgcagccca aaaattagga
     1861 aaagaagaca aggagatggc agtcactttt gtgaccaatg agcgtagtca tgaacttaat
     1921 ctggagtacc gtgacaccga ccgtccgaca gatgtcatca gccttgagta taaaccagaa
     1981 ttggaaattg cctttgacga agaggatttg cttgaaaatc cagaattggc agagatgatg
     2041 tctgagtttg atgcctatat tggggaattg ttcatctcta tcgataaggc tcatgagcag
     2101 gccgaagaat atggtcacag ctttgagcgt gagatgggct tcttggcagt acacggcttt
     2161 ttacatatta acggctatga tcactacact ccggaagaag aagcggagat gttcggttta
     2221 caagaagaaa ttttgacagc ctatggactc acaagacaat aaacgaaaat ggaaaaatcg
     2281 tgacctgata tccagtttag aatttgccat cacagggatt tttactgcta tcaaggaaga
     2341 acgaaatatg cgaaaacatg cagtgacggc tctagtggtt atccttgcag gttttgtttt
     2401 tcaggtgtca cgaatcgaat ggctctttct cctattgagc attttcttgg tagtagcctt
     2461 tgagattatc aactctgcta ttgaaaatat ggtggatttg gccagtcact atcacttttc
     2521 catgctggct aaaaatgcca aggatatggc ggctggcgcg gtattagtgg tttctctttt
     2581 cgcagcctta acaggtgcat tgatttttct cccacgaatc tgggatttat tattttaaac
     2641 agtaagagga aattatgact tttaaatcag gctttgtagc cattttagga cgtcccaatg
     2701 ttgggaagtc aaccttttta aatcacgtta tggggcaaaa gattgccatc atgagtgaca
     2761 aggcgcagac aacgcgcaat aaaatcatgg gaatttacac gactgataag gagcaaattg
     2821 tctttatcga cacaccaggg attcacaaac ctaaaacagc tctcggagat ttcatggttg
     2881 agtctgccta cagtaccctt cgcgaagtgg acaccgttct tttcatggtg cctgctgatg
     2941 aagcgcgtgg taagggggac gatatgatta tcgagcgtct caaggctgcc aaggttcctg
     3001 tgattttggt ggtgaataaa atcgataagg tccatccaga ccagctcttg tctcagattg
     3061 atgacttccg taatcaaatg gactttaagg aaattgttcc aatctcagcc cttcagggaa
     3121 ataacgtgtc tcgtctagtg gatattttga gtgaaaatct ggatgaaggt ttccaatatt
     3181 tcccgtctga tcaaatcaca gaccatccag aacgtttctt ggtttcagaa atggttcgcg
     3241 agaaagtctt gcatctaact cgtgaagaga ttccgcattc tgtagcagta gttgttgact
     3301 ctatgaaacg agacgaagag acagacaagg ttcacatccg tgcaaccatc atggttgagc
     3361 gcgatagcca aaaagggatt atcatcggta aaggtggcgc tatgcttaag aaaatcggta
     3421 gcatggcccg tcgtgatatc gaactcatgc taggagacaa ggtcttccta gaaacctggg
     3481 tcaaggtcaa gaaaaactgg cgcgataaaa agctagattt ggctgacttt ggctataatg
     3541 aaagagaata ctaagtagag gtaggctcat gcctgcttct tgtttttaca gaaggagact
     3601 tatgcctgaa ttacctgagg ttgaaaccgt ttgtcgtggc ttagaaaaat tgattatagg
     3661 aaagaagatt tcgagtatag aaattcgcta ccccaagatg attaagacgg atttggaaga
     3721 gtttcaaagg gaattgccta gtcagattat cgagtcaatg ggacgtcgtg gaaaatattt
     3781 gcttttttat ctgacagaca aggtcttgat ttcccatttg cggatggagg gcaagtattt
     3841 ttactatcca gaccaaggac ctgaacgcaa gcatgcccat gttttctttc attttgaaga
     3901 tggtggcacg cttgtttatg aggatgttcg caagtttgga accatggaac tcttggtgcc
     3961 tgacctttta gacgcctact ttatttctaa aaaattaggt cctgaaccaa gcgaacaaga
     4021 ttttgattta caggtctttc aatctgccct tgccaagtcc aaaaagccta tcaaatccca
     4081 tctcctagac cagaccttgg tagctggact tggcaatatc tatgtggatg aggttctctg
     4141 gcgagctcag gttcatccag ctagaccttc ccagactttg acagcagaag aagcgactgc
     4201 cattcatgac cagaccattg ctgttttggg ccaggctgtt gaaaaaggtg gctccaccat
     4261 tcggacttat accaatgcct ttggggaaga tggaagcatg caggactttc atcaggtcta
     4321 tgataagact ggtcaagaat gtgtacgctg tggtaccatc attgagaaaa ttcaactagg
     4381 cggacgtgga acccactttt gtccaaactg tcaaaggagg gactgatggg aaaaatcatc
     4441 ggaatcactg ggggaattgc ctcaggtaag tcaactgtga caaattttct aagacagcaa
     4501 ggctttcaag cagtggatgc cgacgcagtc gttcaccaac tacagaaacc tggtggtcgt
     4561 ctgtttgagg ctatagtaca gcactttggg caagaaatca ttcttgaaaa cggagaactc
     4621 aatcgccctc tcctagctag tctcatcttt tcaaatcctg aagagcaaaa atggtctaat
     4681 caaattcaag gggagattat ccgtgaggaa ctggctactt tgagagaaca gttggctcag
     4741 acagaagaga ttttcttcat ggatattccc ctactttttg agcaggacta cagcgattgg
     4801 tttgctgaga cttggttggt ctatgtggac cgagatgccc aagtagaacg cttaatgaaa
     4861 agggaccagt tgtccaaaga tgaagctgag tctcgtctgg cagcccagtg gcctttagaa
     4921 aaaaagaaag atttggccag ccaggttctt gataataatg gcaatcagaa ccagcttctt
     4981 aatcaagtgc atatccttct tgagggaggt aggcaagatg acagagatta actggaagga
     5041 taatctgcgt attgcctggt ttggtaattt tctgacagga gccagtattt ctttggttgt
     5101 accttttatg cctatcttcg tggaaaatct aggtgtaggg agtcagcaag tcgcttttta
     5161 tgcaggctta gcaatttctg tctctgctat ttccgcggcg ctcttttctc ctatttgggg
     5221 tattcttgct gacaaatacg gccgaaaacc catgatgatt cgggcaggtc ttgctatgac
     5281 tatcactatg ggaggcttgg cctttgtccc aaatatctat tggttaatct ttcttcgttt
     5341 actaaacggt gtatttgcag gttttgttcc taatgcaacg gcactgatag ccagtcaggt
     5401 tccaaaggag aaatcaggct ctgccttagg tactttgtct acaggcgtag ttgcaggtac
     5461 tctaactggt ccctttattg gtggctttat cgcagaatta tttggcattc gtacagtttt
     5521 cttactggtt ggtagttttc tatttttagc tgctattttg actatttgct ttatcaagga
     5581 agattttcaa ccagtagcca aggaaaaggc tattccaaca aaggaattat ttacctcggt
     5641 taaatatccc tatcttttgc tcaatctctt tttaaccagt tttgtcatcc aattttcagc
     5701 tcaatcgatc ggccctattt tggcttttta tgtacgcgac ttagggcaga cagagaatct
     5761 tctttttgtc tctggtttga ttgtgtccag tatgggcttt tccagtatga tgagtgcagg
     5821 agtcatgggc aagctaggtg acaaggtggg caatcatcgt ctcttggttg tcgcccagtt
     5881 ttattcagtc atcatctatc tcctctgtgc caatgcctct agcccccttc aactaggact
     5941 ctatcgtttc ctctttggct tgggaaccgg tgccttgatt cccggggtta atgccctact
     6001 cagcaaaatg actcccaaag ccggcatttc gagggtcttt gccttcaatc aggtattctt
     6061 ttatctggga ggtgttgttg gtcccatggc aggttctgca gtagcaggtc aatttggcta
     6121 ccatgctgtc ttttatgcga caagcctttg tgttgccttt agttgtctct ttaacctgat
     6181 tcaatttcga acattattaa aagtaaagga aatctagtgc gagtaaaaat taatctcaaa
     6241 tgctcctctt gtggcagtat caattaccta accagtaaaa attcaaaaac ccatccagac
     6301 aagattgagg ttttaaagta ttgtcccaag gaaagaaaag taaccctaca tcttgaatct
     6361 aagtagattt tatggtaaaa taatagggat tttaaggagt ttgatatgta taacctatta
     6421 ttaaccattt tattagtatt atctgttgtg attgtgattg caattttcat gcaaccaacc
     6481 aaaaaccaat ccagcaatgt atttgatgcc agttcaggtg atttgtttga acgcagtaaa
     6541 gctcgcggtt ttgaagctgt aatgcagcgt ttgacaggga ttttagtctt tttctggcta
     6601 gccattgcct tagcattgac ggtattatca agtagataag aaaataatgg gcaggactag
     6661 gtctttgcct ctttttattt ttaaaggatg tttgagaagg ttttacagta aaagaaaatt
     6721 aaaaaatcta gaaagaaaat atgaaagata gaataaaaga atatttacaa gacaagggaa
     6781 aggtgactgt taatgatttg gctcaggctt tgggaaaaga cagttccaag gattttcgtg
     6841 agttgattaa aaccttgtcc ttaatggaaa gaaagcacca gattcgcttt gaagaagatg
     6901 gtagtctgac attagaaatt aagaaaaaac atgagattac cctcaagggg atttttcatg
     6961 cccataaaaa tggctttggc tttgttagtc tggaaggcga ggaggacgac ctttttgtag
     7021 ggaaaaatga tgtcaactat gctattgatg gtgataccgt cgaggtagtg attaagaaag
     7081 tcgctgaccg caataaggga acagcagcag aagccaaaat tattgatatc ctagaacaca
     7141 gtttgacaac agttgtcggg caaatcgttc tggatcagga aaagcctaag tatgctggct
     7201 atattcgttc aaaaaatcag aaaatcagtc aaccgattta tgttaagaaa ccagccctaa
     7261 agttagaagg aacagaagtt ctcaaagtct ttatcgataa atacccaagc aagaaacatg
     7321 atttctttgt cgcgagtgtt ctcgatgtag tggggcactc aacggatgtc ggaattgatg
     7381 ttcttgaggt cttggaatca atggacattg tatctgagtt tccagaagct gttgtcaagg
     7441 aagcagaaag tgtgcctgat gctccgtctc aaaaggatat ggaaggtcgt ctggatctaa
     7501 gagatgaaat tacctttacc attgacggtg cggatgccaa ggacttggac gatgcagtgc
     7561 atatcaaggc tctgaaaaat ggcaatctgg agcttggggt tcacatcgca gatgtttcct
     7621 attatgtgac cgagggttct gcccttgaca aggaagccct taaccgtgcg acttctgttt
     7681 acgtgacaga ccgagtggtg ccaatgcttc cagaacgact atcaaatggc atctgctctc
     7741 tcaatcccca agttgaccgc ctgacccagt ctgctattat ggagattgat aaacatggtc
     7801 gtgtggtcaa ctataccatt acacaaacag ttatcaagac cagttttcgt atgacctata
     7861 gcgatgtcaa tgatatccta gctggcgatg aagaaaagag aaaagaatac cataaaattg
     7921 taccaagtat cgaactcatg gccaagcttc atgaaacttt agaaaacatg cgtgtgaaac
     7981 gtggagctct caattttgat accaatgaag cgaagatttt agtggataaa caaggtaagc
     8041 ctgttgatat cgttcttcgg cagcgtggca ttgccgagcg gatgattgag tcttttatgt
     8101 tgatggctaa tgaaacagtt gccgaacatt tcagcaagtt ggatttgcct tttatctacc
     8161 gaattcacga ggagcctaag gctgaaaagg ttcagaagtt tattgattat gcttcgagtt
     8221 ttggcttgcg tatttatggg actgccagtg agattagtca ggaggcactt caagacatca
     8281 tgcgtgctgt tgagggagaa ccttatgcag atgtattgtc catgatgctt cttcgctcta
     8341 tgcagcaggc tcgttattcg gagcacaatc acggccacta tggactagct gctgactatt
     8401 atactcactt taccagtcca attcgtcgtt atccagacct tcttgttcac cgtatgattc
     8461 gggattacgg ccgttctaag gaaatagcag agcattttga acaagtgatt ccagagattg
     8521 cgacccagtc ttccaaccgt gaacgtcgtg ccatagaagc tgagcgtgaa gtcgaagcca
     8581 tgaaaaaggc tgagtatatg gaagaatacg tgggtgaaga gtatgatgca gttgtatcaa
     8641 gtattgtcaa attcggtctc tttgtcgaat tgccaaacac agttgaaggc ttgattcaca
     8701 tcactaatct acctgaattt tatcatttca atgagcgtga tttgactctt cgtggagaaa
     8761 aatcaggtat cactttccga gtgggtcagc agatccgtat ccgtgttgaa agagcggata
     8821 aaatgactgg agagattgat ttttcattcg tacctagtga gtttgatgtg attgaaaaag
     8881 gcttgaaaca gtctagtcgt agtggcagag ggcgtggttc aaatcgtcgt tcggataaga
     8941 aggaagacaa gagaaaatca ggacgctcaa atgataagcg taagcattca caaaaagaca
     9001 agaagaaaaa aggaaagaaa tctttttaca aggaagtagc taagaaagga gccaagcatg
     9061 gcaaagggcg agggaaaggt cgtcgcacaa aataaaaagg cacgccacga ctatacaatc
     9121 gtagatacgc tagaggcagg gatggtcctg actggaactg aaatcaagag tgtacgagct
     9181 gctcgaatta atctcaagga tggctttgct caagtgaaaa atggagaagt ttggctgagc
     9241 aatgttcata tcgcgcctta cgaagagggc aatatctgga accaggaacc agaacgtcgt
     9301 cgtaaactcc tgctccataa aaagcaaatt caaaaattgg aacaagagac caaagggaca
     9361 ggaatgacct tagttcccct taaggtctat ataaaagatg gctacgctaa gcttctttta
     9421 ggacttgcca aagggaagca tgactatgac aaacgggagt ctatcaaacg tcgtgagcaa
     9481 aatcgagata tcgcgcgtgt gatgaaagct gttaatcagc gataaaaaga ggaattgaaa
     9541 atggaaaaat tagttgccta taaacgcatg cctttgtgga ataaacaaac aatgcctgaa
     9601 gctgttcagc aaaagcacaa tacaaaagtt gggacttggg ggaaaattac tgtcttgaag
     9661 ggagctctca agtttattga attgacagaa gaaggggaag ttctagctga acacctcttt
     9721 gaagcagggg cagacaatcc aatggcccaa cctcaagcct ggcaccgagt ggaagctgcc
     9781 acagatgatg tggaatggta cttggaattt tattgtaaac ctgaggatta ttttgctaaa
     9841 aaatacaata ccaatcctgt tcattcagag gtcctagagg ccatgcagac agtgaaacaa
     9901 gggaaagctt tggatttagg ttgtggtcag gggcgtaatt ctctttttct agcccagcaa
     9961 gattttgatg tgacggctgt agatcaaaat ggactagctc ttgaaatctt gcaaagcatt
    10021 gtggagcagg aagatttgga catgcctgtt ggcctttacg atatcaattc agctagcatt
    10081 gaacaagaat atgattttat cgtttcaaca gttgttctca tgtttctaca agcggaccgc
    10141 attccagcta ttattcaaaa tatgcaggag aaaaccagtg ttggtggtta caaccttatc
    10201 gtttgtgcca tggacacgga ggattatcct tgctcggtta acttcccatt cacctttaaa
    10261 gaaggagaac tggcagacta ttacaaggat tgggaattgg ttaagtacaa tgaaaatcca
    10321 ggccatttgc atcgtcgcga tgagaatggc aatcgtattc aactacgctt tgcgacctta
    10381 ctagctaaga aaatcaagta aacacacatg aagattagga attttcctga tcttttttct
    10441 tttttacgaa tgatatagaa aaggagggaa ttcatgtttg ttgcgagaga tgctagggga
    10501 gaattggtaa atgtgttaga ggataaactt gagaagcaag catacacctg cccagcttgt
    10561 ggaggccaga tccatttgcg tcaaggacca agtgtacgga cgcattttgc ccataaatcc
    10621 ttaaaagact gtgatttttt ctttgaaaat gaaagtccag aacacctggc caataaggaa
    10681 tccctctatc actggttgaa aaaagagaca aaggttcaat tagagtaccc gctttcagaa
    10741 cttaaacaga ttgcggatgt atttgtaaat ggcaatctag ctctagaagt tcagtgtagt
    10801 cccttgcctc agaaagtcct taaagagcga agtgagggct atcgtagtca gggttaccaa
    10861 gtactgtggt tgctgggtca aaaactgtgg ctcaaggagc gtttgactcg tctacagcaa
    10921 ggttttcttt atttcagtca aaacatgggc ttttatgttt gggaattaga caaggaaaaa
    10981 caagttttaa gactcaaata cctgatttac caggatctcc gcggtaaact ccattatcaa
    11041 atcaaggaat tttcctatgg tcaaggtagt ttattggaaa tattgcgtct tccctataag
    11101 agacaaaaaa tatctcattt tacagtttct gaggacaagg acatctgtcg ctatatccgg
    11161 caacaacttt attatcaaaa tctcttttgg atgaaagaac aagcagaagc ctatcaaaag
    11221 ggagaaaata tcctgactta tggactgaaa gaatggtatc cacaaattcg accaatagtg
    11281 ggcaaatttt tccagattga acaagacttg actagctatt atcagcactt ttatacctat
    11341 taccaaaaaa atcctcaaaa tgattggcaa aagctttatc caccagcctt ttatcagcaa
    11401 tatttcttga aaaatatggt agaatagaaa ggatggagga atctaatggt attacaaaga
    11461 aatgaaataa atgaaaaaga tacatgggat ctatcaacga tctacccaac tgaccaggct
    11521 tgggaagaag ccttaaaaga tttaacagaa caattggaga cagtagccca gtatgaaggc
    11581 catctcttgg atagtgcgga taacctacta gaaatcactg aattttctct tgaaatggaa
    11641 cgccagatgg agaagcttta cgtttatgct catatgaaga atgaccagga tacacgtgaa
    11701 gctaagtatc aagagtacta tgccaaggcc atgacactct acagccagtt agaccaagcc
    11761 ttttcattct atgagcctga atttatggag attagcgaaa agcagtatgc tgacttttta
    11821 gaagctcaac caaagctgca ggtttatcaa cactattttg acaagctctt gcaaggcaag
    11881 gatcacgttc tttcacaacg tgaagaagaa ttattggctg gagctggaga aatctttggt
    11941 tcagcaagtg aaaccttcgc tatcttggac aatgcggata ttgtgttccc ttatgtacta
    12001 gacgatgatg gtaaagaagt tcagctatct catgggactt acacacgttt gatggagtct
    12061 aaaaaacgtg aggttcgccg tggtgcctat caagctcttt atgcgactta cgaacaattc
    12121 caacacacct atgccaaaac cttgcaaacc aatgttaagg tgcaaaatta ccgtgctaaa
    12181 gttcgtaact acaagagtgc tcgtcatgca gccctcgcag cgaattttgt tccagaaagt
    12241 gtttatgaca atttggtagc agcagttcgc aagcatttgc cacttttaca tcgctatctt
    12301 gagcttcgtt caaaaatctt ggggatttca gatctcaaga tgtacgatgt ctacacaccg
    12361 ctttcatctg ttgaatacag ttttacctac caagaagcct tgaaaaaagc agaagatgct
    12421 ttggcagtct tgggtgagga ttacttgagc cgtgtcaaac gtgccttcag cgagcgttgg
    12481 attgatgttt acgaaaatca aggcaagcgt tcaggtgcct actctggtgg ttcttacgat
    12541 accaatgcct ttatgcttct caactggcag gacaatctgg acaatctctt tactcttgtt
    12601 catgaaacag gtcacagtat gcattcaagc tatactcgtg aaactcagcc ttatgtttac
    12661 ggagattact ctatcttttt ggctgagatt gcctcaacta ccaatgaaaa tatcttgacg
    12721 gagaaattat tggaagaagt ggaagacgac gcaacacgct ttgctattct caataacttc
    12781 ctagatggtt tccgtggaac agttttccgc caaactcaat ttgctgagtt tgaacacgcc
    12841 attcaccaag cagatcaaaa tggggaggtc ttgacaagcg atttcctaaa taaactctac
    12901 gcagacttga accaagagta ttatggtttg agtaaggaag acaatcctga aatccaatac
    12961 gagtgggctc gcattccaca cttctactat aactactatg tatatcaata ttcaactggc
    13021 tttgcggccg cctcagcctt ggctgaaaaa attgtccatg gtagtcaaga agaccgtgac
    13081 cgctatatcg actacctcaa ggcaggtaag tcggactatc cacttaatgt catgagaaaa
    13141 gctggtgttg atatggagaa ggaagactac ctcaacgatg cctttgcagt ctttgaacgc
    13201 cgtttaaatg agtttgaagc ccttgttgaa aaattaggat tggcataaaa tggttgaatc
    13261 gtatagtaag aatgctaacc ataacatgcg tcgtcctgtc gtcaaagaag aaattgtaga
    13321 cttgatgcgt cagcgtcaaa agcaggtcac aggtttcttg aaagaattgg aagactttgc
    13381 ccgcaaggaa aatattccta ttattcccca tgaaacggtt gcttatttcc gttttcttat
    13441 ggaaaccatg cagcctaaaa atattctgga aattgggacg gctatcggtt tttcagctct
    13501 cttgatggct gaacatgcgc caaatgctaa gattacaact attgatcgta atccagaaat
    13561 gattggtttt gccaaggaaa attttgccca gtttgacagt cgcaagcaaa tcactctcct
    13621 agagggagat gcggtggatg tcttatctac actgacagag tcttatgatt tcgtctttat
    13681 ggattctgcc aagtctaaat acatcgtctt tctgccagaa atcctcaaac atttggaagt
    13741 tggtggtgtg gttgtcttgg atgatatttt tcaaggtggt gatgttgcca aggatattat
    13801 ggaagtccgt cgtggtcagc gaaccattta tcgaggcctt caaaaattat ttgatgcaac
    13861 cttagacaat ccagaactca ccgcaacatt agtgccttta ggagatggta ttctcatgct
    13921 tcgtaaaaat gtagcagatg ttcaactgtc tgaaagcgaa tgattttcag aaaaatttaa
    13981 gaaaaaatag taaaatagat agagtaacac ttatctcaaa ggagtagaca tgaagaaaaa
    14041 attattggca ggtgccatca cactattatc agtagcaact ttagcagctt gttcgaaagg
    14101 gtcagaagga gcagacctta tcagcatgaa aggggatgtc atcacagaac atcaatttta
    14161 tgagcaagtg aaaaacaacc cttcagccca acaagtcttg ttaaatatga ccatccaaaa
    14221 agtttttgaa aaacaatatg gctcagagct tgatgataaa gaggttgatg atactattgc
    14281 cgaagaaaaa aaacaatatg gcgaaaacta ccaacgtgtc ttgtcacaag caggtatgac
    14341 tcttgaaaca cgtaaagctc aaattcgtac aagtaaatta gttgagttgg cagttaagaa
    14401 ggtagcagaa gctgaattga cagatgaagc ctataagaaa gcctttgatg agtacactcc
    14461 agatgtaacg gctcaaatca tccgtcttaa taatgaagat aaggccaaag aagttctcga
    14521 aaaagccaag gcagaaggtg ctgattttgc tcaattagcc aaagataatt caactgatga
    14581 aaaaacaaaa gaaaatggtg gagaaattac ctttgattct gcttcaacag aagtacctga
    14641 gcaagtcaaa aaagccgctt tcgctttaga tgtggatggt gtttctgatg tgattacagc
    14701 aactggcaca caagcctaca gtagccaata ttacattgta aaactcacta agaaaacaga
    14761 aaaatcatct aatattgatg actacaaaga aaaattaaaa actgttatct tgactcaaaa
    14821 acaaaatgat tcaacatttg ttcaaagcat tatcggaaaa gaattgcaag cagccaatat
    14881 caaggttaag gaccaagcct tccaaaatat ctttacccaa tatatcggtg gtggagattc
    14941 aagctcaagc agtagtacat caaacgaata gtccaaatca atgagtcagg gaaaaaaact
    15001 cgacttcagg aaaaaatgaa gcaaacattc ccacaataaa acgcatagta caaggtttgt
    15061 actgacccca aaagttagac aattaattta tctgaaggat ttagttctgt attgcacagg
    15121 gctaagtcct tttagtttta ccttaattcg tttattgttg tagtaatcaa tatagtctat
    15181 aatggcttgt tccaattgat taagtgattt aaatgttttc tcatagccat aaaacatttc
    15241 ggattttaaa atgccaaaga aagattccat cctaccgttg tcttggctgt ttcccttgcg
    15301 tgacatagat gcttgaattc ccttactctc taggaagcga tgataagaat cgtgttggta
    15361 ttgccagcct tggtcactat ggagaatcgt attctcgtag tgcttctctt tgaatgcctg
    15421 ttccaacatt aacgatcaat caatttaatc atgtacctaa tattagaatt gtttatacca
    15481 aatttatttg aaagcttctc taagctatat ccttgttttc taagttcata gatctgaact
    15541 ttatcatcat aagttaattt cataataaaa acacctcaaa agttagattt tttctgtcta
    15601 acttttgggg tgtagttcat gtacacctga tatgatgcgt tttataattt taaagacttt
    15661 ttgaccagcc tcattttttt aacttgatac tcagtgaaaa gcaaagatta aactaggaag
    15721 ctagctgtag gctgctcaaa gaacagcttt gaggttgcag ataaaacttg tgaggtaacc
    15781 aacatatata atgtgaagct gacgtggttt gaatagattt tagaagggta tgagtctgga
    15841 agttttaatg gataatgcaa gattccatag aatgggtaag ctagagttct tatgtgaaga
    15901 gtttgggcat aaacttttac cttttcctcc ctactcatct tagtatagaa aagtgaatct
    15961 aaaatagtac ataactgctt ctaaaacatt cttataaatt gatttaaatt ctcaaatcat
    16021 attattcagt tcttatttca ttttgctcta caatcctgtt gagaagacac gtgttcatat
    16081 caaaaaggta ttggcaagtt gcaatacctt tttacaaggt tcttttgtct tatttttgtt
    16141 tcaactgact atatctccta tggttctagt tcagaaggct aggctataat tatgattgat
    16201 aagaagtatc attccaagta ttgagagtga atgtttcaaa atcatgggtt tctataatgg
    16261 tcaggctggc atttgctaga ccgccatctt tacgaagaag tggttcttta tagcctagga
    16321 gagtacgaag actggcagta agattggcgc cgtgtccgac aattagaata cgctcagctg
    16381 gactatcttt taatgatttg ataaattgga tggtccgctg agttgtacta tagagggatt
    16441 cggctccgaa cattcgagtg tcaaattgag caagatttga acgaaaagcc tggatttgtt
    16501 gcgggtaaat agcttccagg gttgcaattt tcaaaccttc taacttccca agttgccatt
    16561 cacggagatt aggaacgatt tctaaagaac agggggtatg gagttgactt tggataatct
    16621 cagcagattt gaccgctcga ggtaaatcac ttgaataaat ctgatcaaaa ggaatttcct
    16681 tgagatactg gccaagtcgt tttagggttt caatggattc aggaagaaga ggagaatcac
    16741 cgctagcacc ttgaaaacga ccttcttggt tccagagggt acgaccgtgg cggacaaagt
    16801 agagtttcat tacttgatgt cctccaaaat atctacaaag tctgccttta caaagctagc
    16861 caagtcttgt ggcgcgacga taatgctgtg tccgacttcg cctgcagaga caatcattcg
    16921 atccaaatct agagcaattt tatcgataaa aatgggataa ttgtgtttct gacgaattcc
    16981 gacaggatta ttggctccat gaatgtaacc agttgttttt tctaagtcct tttgtggaat
    17041 catgctcact tttttattgc cagaaatttt agctagtttc ttttcagaca agtgctgagt
    17101 gatagggaca attccgataa tcggtccggt cttgtctccc aaaagcgcca aggttttgaa
    17161 aatctgatct cgttcataac cttgaggaag ctctccttct agggcattga tttgaatccc
    17221 ctgatgaggg atagctgctt tagataggat ttgttccacc aatgtttttt tgattttaac
    17281 tttttttgcc attatttata tttatcctcc aattgactca tccaaatacc aagccagatt
    17341 cccagcgcaa agaagaaggc gatgatgaca taaccgacaa gtgaaagtcc tgtgtattgg
    17401 atactttcag cgtttcctgc atttggaatt aagatcaaaa gggtacttga taggacgata
    17461 ccgatgatga aatgatagac gtgtgagtgg tagttgttta aggcataatc catcaatttt
    17521 gaaaaaacga tgagagttgc acctgcacca attccaatcg gaaagaaggt tcccaagaga
    17581 tcaaaagttt taaaaccagt caacatagga gcatagagtc ccaaaatcaa aagtaagttc
    17641 gatgggctga ggccaggaac caagacgcca agggccaata gtgcgcctgc taggacgaag
    17701 ttaagaaagc tggcgcttaa ggttccaacg acaaaattta aggcatagag tcctaatcca
    17761 gaaatgataa aggttgtcca taaccaagct aaatcaatct tgtctcggtc agattctcga
    17821 gttgattctt tgaggaggct aggaactgta ccgataatag ctcccgcaaa gctccataat
    17881 acaaagacct gataattttc aagcaggtat tcaatcgggt aggaaaataa gccgattccc
    17941 agaagcatac cgatggcaac tggaataaag tacaaaacat tttctttaag gtctttaaag
    18001 ggatgggcca gaaagccaat cattcgttca tagattccta agattgctgc tagaacccct
    18061 ccggaaattc ccggtaggat aaatccaaga gcaattacaa tccctttaat aacgcgtgct
    18121 aaccatgaga gcatatattt cctccaacta tttctatttc aaaaaatcct tactatattg
    18181 tatcacaatc agacacaaaa agaaaaagca aatgataaac aaatgctttt aaggttttaa
    18241 aaaaagtttt cgaaaggttt cttctttatt ttttaaggga gagataacgt tgatatctaa
    18301 atcgtggtca aagccggcaa tttttccttt agatgtgtat tggtgaatat cataatctaa
    18361 atcagtttta ggactgctct ccaaaaatcc tgagtctgag ccgtaggacg gaatccaaac
    18421 agaggtaaac ttgcctgtat caatactgtg ttcttccatg aagtagacac caacgtagat
    18481 gccgatgttt ttagcaccta gtgatgctag ttttgctcga aagttttcga caccttcgtt
    18541 catattagac atggttttgt cttccacgtc aagccaatag taactagggc tgtaaggaga
    18601 ggcagcattg tagaaaactt cggcagcctt ttccatttct tggacacttt ttccagctac
    18661 ataagcgtag acagcaactg ggacattccg cttttgaagt tcagtgatat gactcttata
    18721 ggccttgtct attccattga taaatgaagc atcattttct tttgttgttt gagcaccact
    18781 gtgaacacga acaatagcac ctgaaatatt ttgtgagagg gcatcgtagt tgatttcctc
    18841 aggacgctgc cagccagaga ggtcaataat cggtttgtct aagtgtttca aagcctgtgc
    18901 tatattggat tttgttttaa acgattggct gtcattaagt gggcgattga tgattaaaat
    18961 gaacatcata atcccaaaaa aactaaataa aataagtgga tgaatttgtt ttctcatatc
    19021 ttataagtct accctaaaaa tcaaaaaaaa tcaaaaaaat gggttaagga agagacttta
    19081 gagcattttt tcattcaaga gtgcggaatg atttgaaata tggtataata aaagggaatt
    19141 tctacagaaa agagaagatt atgtcaaatt ttgccattat tttagcagcg ggtaaaggga
    19201 ctcgcatgaa atctgatttg ccaaaagttt tgcacaaggt tgcgggtatt tctatgttgg
    19261 aacatgtttt ccgtagtgtg ggagctatcc aacctgaaaa gacagtaaca gttgtaggac
    19321 acaaggcaga attggttgag gaggtcttgg ctggacagac agaatttgtg actcaatctg
    19381 aacagttggg aaccggtcat gcagttatga tgacagagcc tatcttagaa ggtttgtcag
    19441 gacacacctt ggtcattgca ggagatactc ctttaatcac tggtgaaagc ttgaaaaact
    19501 tgattgattt ccatatcaat cataaaaatg tggccactat cttgactgct gaaacggaca
    19561 atccttttgg ctatggacga attgttcgta atgacaatgc tgaggttctt cgtattgttg
    19621 agcagaagga tgctacagat tttgaaaagc aaatcaagga aatcaacact ggaacatacg
    19681 tctttgacaa cgagcgtttg tttgaggctt tgaaaaatat caataccaat aacgctcaag
    19741 gcgaatacta tattacagac gtcattggta ttttccgtga aactggtgaa aaagttggcg
    19801 cttatacttt gaaagatttt gatgaaagtc ttggggtaaa tgaccgtgtg gcgcttgcga
    19861 cagctgagtc agttatgcgt cgtcgcatca atcataaaca catggtcaac ggtgttagct
    19921 ttgtcaatcc agaagcaact tatatcgata ttgatgttga gattgcttcg gaagttcaaa
    19981 tcgaagccaa tgttaccttg aaagggcaaa cgaaaattgg tgctgagact gttttgacaa
    20041 acggtactta tgtagtggac agcactatcg gagcaggagc ggtcattacc aattctatga
    20101 ttgaggaaag tagtgttgca gacggtgtga cagtcggtcc ttatgctcac attcgtccaa
    20161 attcaagtct gggtgcccaa gttcatattg gtaactttgt tgaggtgaaa ggatcttcaa
    20221 tcggtgagaa taccaaggct ggtcatttga cttatatcgg aaactgtgaa gtgggaagca
    20281 acgttaattt cggtgctgga actattacag tcaactatga cggcaaaaac aaatacaaga
    20341 cagtcattgg agacaatgtc tttgttggtt caaattcaac cattattgca ccagtagaac
    20401 ttggtgacaa ttccctcgtt ggtgctggtt caactattac taaagacgtg ccagcagatg
    20461 ctattgctat tggtcgcggt cgtcagatca ataaagacga atatgcaaca cgtcttcctc
    20521 atcatcctaa gaaccagtag gagcctatca tggagtttga agaaaaaacg cttagccgaa
    20581 aagaaatcta tcaaggacca atatttaaac tggtccaaga tcaggttgaa ttaccagaag
    20641 gcaagggaac tgcccgacgg gatttgattt tccacaatgg ggctgtctgt gttttagcag
    20701 taacggatga acaaaaactt atcttggtca agcagtaccg caaagctatc gaggctgtct
    20761 cttacgaaat tccagccgga aaattggaag taggagaaaa cacagcccct gtggcagctg
    20821 cccttcgtga attagaggaa gaaacagcct atacagggaa attagaactc ttgtacgatt
    20881 tttattcagc tattggcttt tgtaatgaga agttaaaact atatttagca agcgatttga
    20941 caaaagtgga aaatccgcgt ccgcaggatg aggatgaaac cttggaagtc cttgaagtga
    21001 gcttagaaga agcgaaagaa ttaatccaat caggtcatat ctgtgatgcc aagacaatta
    21061 tggctgttca gtattgggag ttgcagaaaa aatagaggag gtcagtatgg gtaaatcttt
    21121 attaacggat gaaatgattg aaagagctaa tagaggcgaa aaaatttcag gtcctccttt
    21181 gctagatgat aatgaggaaa ctaagatttt accaacctct tcttcccgtt ttggttatgc
    21241 caatcctaag gatcatggtt ttagccagga aaccttgaag attcaggtcg aaccatctat
    21301 tcataaaagc cgtcgcattg aaaataccaa gagaaatgtc ttcaattcta agttgaataa
    21361 aatcttattc gcggtcatct ttctcttgat tttgcttgtt ttagcaatga aacttttgta
    21421 atagaaaagg aattgaaatg aaaataggaa ttattgctgc tatgccagaa gaactggctt
    21481 atctggtcca gcatttagac aatgcccagg agcaagttgt tttggggaat acctatcata
    21541 caggaaccat tgcttctcat gaagtcgttc ttgtagaaag tggaattggt aaggtcatgt
    21601 ctgctatgag tgtggcgatt ttggctgatc atttccaggt ggatgccctt attaatacgg
    21661 gttcagctgg ggcagtagca gaaggtatcg ctgttgggga tgtcgtgatt gctgacaaat
    21721 tagcctatca tgacgtggat gtcacagctt ttggctatgc ttatggacaa atggcgcaac
    21781 aaccgcttta tttcgaatca gacaaaacct ttgttgctca aatccaagag agtttatctc
    21841 aattggacca aaactggcat cttggtttga ttgctacagg agatagtttt gttgcaggaa
    21901 atgacaagat agaagcgatt aagtcccatt tcccagaagt tttagccgtg gagatggagg
    21961 gggcagctat tgctcaagca gcgcatgccc tcaatctccc agtcttagtc atcagagcta
    22021 tgagtgacaa tgccaaccat gaagcaaaca tcttttttga tgagtttatt atcgaagctg
    22081 gacgtcgctc tgcccaagtc ttgttggcct ttttgaaggc tttagattaa gcggaaattt
    22141 gacagttttt ctagcttatg ataagattta agtaaagaaa agctagaaaa cgtttcagag
    22201 gatattatga gtattgaaat gaccgtcagt gagattgcag aggtcttagg attatctcgc
    22261 caagcaatca ataaccgtgt caaagaatta ccagaagaag acacagataa aaatgacaaa
    22321 ggggtaacag ttgttaccag aagtggcttg attaagctag aagaaatcta taaaaaaacg
    22381 atttttgaag atgagcctgt cagtgaagat gtcaaacaac gtgaactgat ggagattcta
    22441 gtggatgaga agaatgcaga aattcttcgt ctttatgaac aattaaaagc caaggatcgt
    22501 cagttatcag aaaaagacga gcagatgcgt atcaaagacc gtcagattgc tgagaaagac
    22561 aaacaattag atcagcaaca acaattgacc cttcaagcca tgaaggatca agaaaatctt
    22621 aagctagagc tggaccaagc aaaagaagaa gtccaatcca ctaagaaagg cttttttgct
    22681 cgtttatttg gaggataatc aaggagctgt ttaggttaaa tgctaacctg atggcttctt
    22741 ttgtttgtga atagtatagt tgattagaac agagacagta gaggagaggt acagaatgga
    22801 acgattagaa gattacattg cttttgattt agaatttaat cagcacgaag gacaaacaca
    22861 cttgattcaa gtatcggcag tgcgttttag agatggtcgg gaaatcgatg cctatgattc
    22921 ctatgttcat accagcgtcc ctctaaaaag ctttatcaat ggtttgaccg ggattacagc
    22981 tgagacctta aaagatgctc ctccagttga gaaagtctta gaagaattcc aagagtttgt
    23041 gggttctttg ctgatgatag gctacaatgc tgctaaaagt gatttaccta ttttagcaga
    23101 gcatggttta gactatagcc aacagtacaa ggtggatttg tatgatgaag cttttgaacg
    23161 tcggagttca gatttacatg gtattgccaa tctcaaattg caaactgttg cctcatttct
    23221 tggatttcaa ggtcagtctc ataatagttt agaggatgct cggatgacgg cgcgtgttta
    23281 cgaatccttc ttagagtcgg atcaagctag ggaattgtta gagacagaaa gtagcttatc
    23341 aaacaatcct tttggtggct tggacttgtc tcaattattt gactaggagt gcctatgaaa
    23401 cctgaaaaac ctaaaaaatt gggtcttaaa cagatttacc tcaatcttga taaaatcctc
    23461 tttctatttt tcttgatttt tatgatagtg gagtatttgt gggtaccatt caattcatgg
    23521 ttggctagct tcttattaga tcagacaggt tatcttttta tttcctataa caatgtctta
    23581 gccatcctta ctcattctcc attgattagt ctagcttttt tagccttgat tgtaattaac
    23641 cttctggttg cttattttca aataggactc ctctttattg gtgctcgtca tctcctctat
    23701 aatgaaaagc gaaggctaat tgagtatatc cgcaaggttt tccatgaaag ttttggattt
    23761 atgaaaaagc taacttgcgc taaagccttg tttatctttt tctatatagc tatgctgttt
    23821 ccttttatac ggaaaatgct gaagatttat tatcttaata aaatcgtcat tccagagttt
    23881 atccaagctt atttagaaga tagatattgg atgtggtggc tgagcatcct acttctatct
    23941 cttatctttc tctatgtctc tgtcagattg atgtttgccc ttccgaagat tgtatatgat
    24001 cagctgactg ttcgagaagc agtgatgttt agcttggaga aaaccaagaa gagagttact
    24061 ttttatgctt ggaatttatt ttacatcttg ctcaaagcac atttattatt ttatcttcct
    24121 ttgatccctt tattattggc tcaaactttg gtagatgata tcactcagag agagtctctg
    24181 attcttggta ttttgaattt tgtcgtgatt aaaaatctct attatatggc tctgacttat
    24241 tttttggtta aatttgtttc atttttgaca ggaaaggagc tggatatgct tcctaggaga
    24301 gaaaaagatc acatcgtgcg atggggtgtc atgacttgtg ccagtctttt ctttgcctta
    24361 gaaggttata tttatctgga ggctcccatg gttcatctac ctcaacttat ttctcaccga
    24421 ggggtttcca atgcaaatgg gattcaaaat acagtagagt ccttggaaac tacagcacaa
    24481 ctcaaaccag acttggtgga gacggacgtg caggaaacaa aagatgggca gtttgtcatg
    24541 atgcatgatg ctaacttgaa aaatctagca ggtatcaata aaagtcctca agacttaaac
    24601 ttggaggagc ttaaagggat tgatattttt gaaaatggct accagactaa aatttcaagc
    24661 tttgaagatt atctcagtcg agccaacgaa cttggtcaaa aattactaat tgaaattaaa
    24721 accagtaaaa aagatagtcc agacatgatg aaccgctttt tagcccgtta tgctgcaaag
    24781 ctcaagattt atggacatca aatccagtct ttagactacc atgttgtcga aaaagtaaga
    24841 cagtatgatg ccgaactgcc agtttatttc atcatgccct acaattctgt ctttcctaaa
    24901 acaagagcga caggatatac tatggagtac tcaaccttgg atgaatattt tgtaagcaaa
    24961 ctatggacaa cggatcagaa actttatgtc tggactgtca atgattcaga agctatcagc
    25021 aaatctcttc acttaggagt agatggagtg attacagatg atttggaaaa agttcagcgg
    25081 gaaatagaag tagcccaaga agatccagaa tatacggatt tgctcttgaa aaaagcattg
    25141 gaattctttg aattttagta ataaaaaaga ggaacggttg ttcctcccat gataggtaag
    25201 tattcttgtg aatgcttgct tttttgtggt tgcaatccgt ttacgagaat tgtttgtatt
    25261 gttcttgttt caatttactt tatagtgctt tgaagttgga atgctacact ataacttcta
    25321 aaatatagta aaatgaacca aaaatagtac acaatgtggt ataatctttt tatggcatat
    25381 tcaatagatt ttcgtaaaaa agttctctct tattgtgagc gaacaggtag tataacagaa
    25441 gcatcacacg ttttccaaat ctcacgtaat actatttatg gctggttaaa gctaaaagag
    25501 aaaacaggag agctaaacca ccaagtaaaa ggaacaaaac caagaaaagt tgatagagat
    25561 agactta
//
LOCUS       DAVEHY010000031        24073 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVEHY010000031 DAVEHY010000000
VERSION     DAVEHY010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.031"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..156)
                     /locus_tag="VUZ44_001555"
     CDS             complement(<1..156)
                     /locus_tag="VUZ44_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320440.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKK"
     gene            complement(295..819)
                     /locus_tag="VUZ44_001556"
     CDS             complement(295..819)
                     /locus_tag="VUZ44_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU0320441.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(872..1108)
                     /locus_tag="VUZ44_001557"
     CDS             complement(872..1108)
                     /locus_tag="VUZ44_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU0320442.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(1176..2096)
                     /locus_tag="VUZ44_001558"
     CDS             complement(1176..2096)
                     /locus_tag="VUZ44_001558"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU0320443.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            2286..2689
                     /locus_tag="VUZ44_001559"
                     /pseudo
     CDS             2286..2689
                     /locus_tag="VUZ44_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2905..3486
                     /locus_tag="VUZ44_001560"
     CDS             2905..3486
                     /locus_tag="VUZ44_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU0320444.1"
                     /translation="MYYAEHPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            3483..4760
                     /locus_tag="VUZ44_001561"
     CDS             3483..4760
                     /locus_tag="VUZ44_001561"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU0320445.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            4778..5440
                     /gene="deoC"
                     /locus_tag="VUZ44_001562"
     CDS             4778..5440
                     /gene="deoC"
                     /locus_tag="VUZ44_001562"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU0320446.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            5427..5816
                     /locus_tag="VUZ44_001563"
     CDS             5427..5816
                     /locus_tag="VUZ44_001563"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU0320447.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5906..6958
                     /locus_tag="VUZ44_001564"
     CDS             5906..6958
                     /locus_tag="VUZ44_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU0320448.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7102..8637
                     /locus_tag="VUZ44_001565"
     CDS             7102..8637
                     /locus_tag="VUZ44_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320449.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            8630..9688
                     /locus_tag="VUZ44_001566"
     CDS             8630..9688
                     /locus_tag="VUZ44_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320450.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            9691..10647
                     /locus_tag="VUZ44_001567"
     CDS             9691..10647
                     /locus_tag="VUZ44_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320451.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            10732..12079
                     /locus_tag="VUZ44_001568"
                     /pseudo
     CDS             10732..12079
                     /locus_tag="VUZ44_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(12122..12763)
                     /gene="plsY"
                     /locus_tag="VUZ44_001569"
     CDS             complement(12122..12763)
                     /gene="plsY"
                     /locus_tag="VUZ44_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU0320452.1"
                     /translation="MITIILLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            12899..14842
                     /gene="parE"
                     /locus_tag="VUZ44_001570"
     CDS             12899..14842
                     /gene="parE"
                     /locus_tag="VUZ44_001570"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU0320453.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLADKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            15262..17733
                     /gene="parC"
                     /locus_tag="VUZ44_001571"
     CDS             15262..17733
                     /gene="parC"
                     /locus_tag="VUZ44_001571"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU0320454.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDVAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            17865..18887
                     /locus_tag="VUZ44_001572"
     CDS             17865..18887
                     /locus_tag="VUZ44_001572"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU0320455.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMANSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            18943..19617
                     /locus_tag="VUZ44_001573"
     CDS             18943..19617
                     /locus_tag="VUZ44_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0320456.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGFAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQIPK
                     RTRKIH"
     gene            19686..20375
                     /locus_tag="VUZ44_001574"
     CDS             19686..20375
                     /locus_tag="VUZ44_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU0320457.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            20372..21295
                     /locus_tag="VUZ44_001575"
     CDS             20372..21295
                     /locus_tag="VUZ44_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU0320458.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            21310..21954
                     /gene="pcp"
                     /locus_tag="VUZ44_001576"
     CDS             21310..21954
                     /gene="pcp"
                     /locus_tag="VUZ44_001576"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU0320459.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIETIVDYKDKDLQLVGGETH"
     gene            22122..22352
                     /locus_tag="VUZ44_001577"
     CDS             22122..22352
                     /locus_tag="VUZ44_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU0320460.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            22402..22482
                     /locus_tag="VUZ44_001578"
     tRNA            22402..22482
                     /locus_tag="VUZ44_001578"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22436..22438,aa:Tyr,seq:gta)
     gene            22492..22563
                     /locus_tag="VUZ44_001579"
     tRNA            22492..22563
                     /locus_tag="VUZ44_001579"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22524..22526,aa:Gln,seq:ttg)
     gene            22725..23927
                     /gene="rpsA"
                     /locus_tag="VUZ44_001580"
     CDS             22725..23927
                     /gene="rpsA"
                     /locus_tag="VUZ44_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU0320461.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         7246 a         4243 c         5438 g         7146 t
ORIGIN      
        1 tttcttcatt agacttccac aatcagggca agatggagcc tcataatcca gcttagcgat
       61 aatttctttg tgggtatcca tattgatgat atctagaatc ttgatgtttg ggtctttaat
      121 atcgagcagt tttgtgataa aatgtaattg ttccatatga atctttctaa tgatggtttt
      181 gtcgcttttc attataggtc atatgggact ttttttctac aataaaatag gctccataat
      241 atctatagtg gatttaccca ctacaaatat tatagagccc aaaaaggaag ccctttatga
      301 attgtaggac ttccttttct tatccagaaa ttgatctagc tctctctgat ttcgaagaat
      361 agtgacttta tgtgaatatt cttggcaaag tttttggtaa ttttcttttt gagttttgct
      421 acgtccatcc caaagaatcc atctgataaa ctcccagtca aagcgttcag ggcaatctgc
      481 cgccatactt tctctgactt ttccacggta tttaagataa cgcttaaagg ctctaaagag
      541 acaggtcaat ggcgaaaaat tgagaaagat gatttggtca gcttcttgca ttcgttcttg
      601 gtagtagcac caagaataat taccatcgat gacccaagct ttatgcttgg tgagaaagtt
      661 ttttatctcg gttaacatcc attcgcagtc actgtcttgc caaccaggtt gaaattggag
      721 tgtgtccatg tgcagttttg gaatggagta gtagttagat aacttttctg ctagagttga
      781 cttaccagaa ccagaatatc cgataattgt gattttcatt ttctaccttt tcctatttgg
      841 agacaaaaaa acagcctcta tggactgttt cttatttagc aagtttagct gaaagacgag
      901 ctttatcgcg gcttgctttg tttttgtgaa tcaaaccttt agtttctgct ttatcgatag
      961 ctgagctagc agcacggaaa agttcttcag atgggtttgc ttcgaaagct tttatagcag
     1021 tacgcatagc tgatttttga gctgagttct tttcgttttg tttaacgttc aattcagcgc
     1081 gtttgatagc tgatttaatg tttgccaatg ttcttacctc catatttact aactatacca
     1141 ttatatatga aaacttacgt tttgacaagg gaaaattatt tttttaagta aatttcatcg
     1201 atttcatggt tcttgctttt atgaagaatc acttctgcac gatttctggt tggttcaata
     1261 taattttgta gatttgtgag attgatactg gtccagacct gatgggcaaa ggcttccact
     1321 tccccaatcg gcatctgagt aaaacgataa tagtagctat cagggtcgtt ttgggctaga
     1381 ctcagcattt tcaagaaacg gtccagatac caactttcaa tatcatccac tccagcatct
     1441 acatagatgg aaaagtcaaa gaagtcagtg atatagagac gatcgttttg tggattttga
     1501 aagacattaa ttccctcaac aattacaaaa tcagcagctt tgacactttg tttcttttcg
     1561 ggtacgatgt cgtaaacttc atgagaatag acaggaatat ctacatcttg tccatttttg
     1621 atgcggtcca agaagttgag aagagcttcc atatcatagc tttcaggaaa tcctttacga
     1681 tttaaaatcc cctgctcaat caaggtttga ttgggataga gaaaaccatc agttgtaacc
     1741 aactcaaccg tagcatctgt aaacgtacgg gacagtagga tttgaagtag gcgactggtt
     1801 gtggattttc caacggcaac actcccagaa accccaataa taaaaggttg agatttactt
     1861 tcacgttgga ggaaaattcc ttttgaaaag gctaaatctt ccttagttcg cttgtaaatc
     1921 tgaatcagat gagccaaggg gagatagata tctgtaacgt cttggagact gatttggtca
     1981 ttaaaactct tgatagattc caattcttct tctgtcaaag gaggtgttgt ctttcgatgt
     2041 aaagattgcc aagtctggcg gctgattttt tcaaaatgta aaaattcgtt ggtcatttgt
     2101 tttcccctag atattttgtc tatcatacca taaaaagcta aaaaaataaa gcggtttctt
     2161 gaatgtggta agtcaatggt atatagtata agtgatcaat ttattgatga aataggagat
     2221 agattctact gatttataag cttataaagg gggcttttta gttcacaact tataggaggt
     2281 gtactatgaa aatcttaaaa cgttacatat tggaactctg ttttatttta agttttgctt
     2341 taccttttat aaaaggaacc aatgcagata atggtagatg ctttgtggaa acctattacg
     2401 gttttacttt tttgatggaa catgctattg taacagctgt ctttatctgt tcgttcttaa
     2461 ttgctttctt actaaaaaac gatggacgaa atggattgct gcgggtagtt attgcttttt
     2521 agtcctacgg attgcgacag agggttattt cttccacatg tcactagaag atttgatacg
     2581 actttggaca agtttggaaa tcctgacaca aacgtatcag ttgggctttt atctaaacat
     2641 tttgttagga attttgttga taataaagta ttttaaggtt aagcaataga aataataatc
     2701 tgcctgatta tagatgataa actttttgtt tttatctgga ctgtgatatt tatagttcta
     2761 aatggtttat tatttataag tgttgaaaga gattgaagaa aatggcttcg tgacttgctt
     2821 tcttcggtct ttttcgtttt attatcaatt tgtaaacgat ttacaatttg agtcaaatta
     2881 tggtaaaata gtgtcatgag taaaatgtac tatgcagaac atcctgacgc tgctcacgac
     2941 attcatgagt tgagagtgga cttgttggga gaaaaaatga cttttttgac agatgcgggt
     3001 gtttttagca agaaaatggt tgactttgga agtcaactct tgctcaagtg tctggatgtc
     3061 aaccaaggag agacagtcct agatgtaggc tgtggctatg gtccattagg tttgtccttg
     3121 gtcaaggttt acggagttca ggcgaccatg gttgatatta acactcgtgc cctggattta
     3181 gctcagagaa atgctgaaaa aaataatgca aaagcgacga tatttcaatc taatatttat
     3241 gcaagagttc aagggcgatt tgaccatgtc atttccaatc ctcctatccg tgcgggcaag
     3301 caagtcgttc atgaaatcat cgagaaaagt aaagatttct tggaaattgg tggagatttg
     3361 accatcgtca tccagaaaaa acaaggagct ccaagtgcca agtctaagat ggaagatgtg
     3421 tttggcaatt gtgaaatcct taaaaaagac aagggatact atatccttag aagtgtgaaa
     3481 gaatgagagc agttgattta atccaaaaaa aacgagacgg tcaagaactg acttcaagtg
     3541 aaattgaatg gctgatagaa ggctatgtat caggaactgt tcctgattat cagatgtctg
     3601 cctttgctat ggctgtttat tttaaaggaa tgacgactcg agaaatctct gatttaacga
     3661 tgaatatggt taagactggg caagagtttg acctgtcagc cattgatggt gtgaaagttg
     3721 acaagcattc tactggcggt gtcggcgata aggtaacctt gattttagct cctcttgttg
     3781 ctagcttcgg tgtgcctgta gcaaaaatga gtggtcgtgg tcttggccat acaggcggaa
     3841 caattgataa attggagtcc attaagggct atcaagtaga acgtagtcaa gaggatttta
     3901 ttcgtcaggt tcaggatatt ggagtatctg tcattgggca atcagaccag ctggtcaaag
     3961 cagataagct tctctatgcc cttcgtgatg tgaccgcaac tgtcgacacg attcctttga
     4021 ttgcgagttc ggtgatgagc aagaaaattg cggcaggggc ggatgctatt ttgctagacg
     4081 tgactgtcgg tgagggtgcc ttcatgaaga cggttgatga ggcgcgtgag ttggctcaaa
     4141 ctatggtaga tcttggtaag gttgttggac ggaagacagt agcagtgatt acggatatga
     4201 gccagccttt gggacgagcg attggaaatc gtctggaaat ccttgaagca ttggagattt
     4261 tgcaaggtca aggacgtcag gatattaccc actttatttg tgaattggct caaattatgc
     4321 ttggtttggc aaatgttaac aagactgttg aagaagttca ccaacatctt gagaatggtc
     4381 aagcactggc taagtttgag gaaatggtgc aagcccaagg tggagacttg gaagacctct
     4441 atcgtcctgt aaatgtagct catgtggtgg aaatccctgc tcaggaaacg ggtgtcattt
     4501 cagctcttcc agctatggac tttggtcttt atgccatgag gctgggtgct ggtcgtgcag
     4561 ttaagtctga tgccttggac tatgaaacag gaattgtttt tgaaaagaag attggagact
     4621 ccgttcaaaa gggtgaaatt gttgcaaaag tatacacaaa tgaaaaaatt ccacctcaac
     4681 tagttacaga tttccaaaaa tgtgttaaaa taagtgatga agtgaaaaaa atccgtgaaa
     4741 ttgtagaaat catctcctaa atggagggaa aaccgaaatg aaattaaata aatatataga
     4801 tcatacgctt ttaaaacaag atgcaaagaa aaaacaaatt gatagtttgt tgtctgaggc
     4861 tagagagtat gactttgcca gtgtttgcgt taatccgacc tgggttgaac atgctaaaaa
     4921 aggacttgaa ggcacagatg ttaaggtttg cacagtagta ggtttccctt tgggagcaac
     4981 aacttcagcc gtgaaagcat ttgagacaaa agaagctatc caaaatggtg cagatgagat
     5041 tgatatggtg atcaatgttg gagctctcaa atcaggtaat ttagccttgg ttgagtcaga
     5101 tattcgcgca gtagtggaag caagtggtga taagttagtg aaagtcatta ttgaagcttg
     5161 ccttctgaca gaccaagaaa aaattgttgt ttgccaattg gcccaaaaag ctggggctga
     5221 ctttgttaaa acatctactg gcttttcaac tggtggtgct acgatagcag atgttagatt
     5281 aatgcgtgaa acagttggat ctgatatggg agtcaaggct gctggtggag ctcgttctta
     5341 tgcagatgct cttgcctttg tcgaagcagg tgcgacccgt atcggaacgt cagctggggt
     5401 agctatttta aaaggagaat tggcagatgg cgactactga gttgattgaa ctggcaattg
     5461 aaaccagcaa acatgcctat gtcccctatt ctcactttcc tatcggagca gttttagtag
     5521 ccaaagacgg aagtgtttac acgggagtga atatcgaaaa tgctagctat cctttgacca
     5581 attgcggtga gagaacagct atttttaagg ctatatctga aggccaaaga gaattttcag
     5641 aattgattgt ctatggtcaa actgaaaaac cgatctcgcc atgtggtgct tgtcgccaag
     5701 tgatggctga attttttgaa caagatctaa aagtgacctt agtcgcaaaa gataaatcga
     5761 cggtcgagat gacggtcggg gaattacttc catactcttt tacagactta aactagtctg
     5821 agtcgctctc tgagtggcac ggtccttgtg gccaaccaat ccatacttgc aacatcgttg
     5881 cacatcttat ttaggaggtt cagtaatgaa caagaaacaa tggctaggtc ttggcctagt
     5941 tgcagtggca gcagttggac ttgctgcatg tggtaaccgc tcttctcgta acgcagcttc
     6001 atcttctgat gtgaagacaa aagcagcaat cgtcactgat actggtggtg ttgatgacaa
     6061 atcattcaac caatcagctt gggaaggttt gcaggcttgg ggtaaagaac acaatctttc
     6121 aaaagataac ggtttcactt acttccaatc aacaagtgaa gctgactacg ctaacaactt
     6181 gcaacaagcg gctggaagtt acaacctaat ctttggtgtt ggttttgccc ttcacaatgc
     6241 agttgaagaa gcagctaaag aacacactga cttgaactat gtcttgattg atgatgtgat
     6301 taaagaccaa aagaatgttg cgagcgtaac tttcgctgat aatgagtcag gttaccttgc
     6361 aggtgtggct gcagcaaaaa caactaagac aaaacaagtt ggttttgtag gtggtatcga
     6421 atctgaagtt atctctcgtt ttgaagcagg attcaaggct ggtgttgcgt cagtagaccc
     6481 atctatcaaa gtccaagttg actacgctgg ttcatttggt gatgcggcta aaggtaaaac
     6541 aattgcagcc gcacaatacg cagccggtgc agatattgtt taccaagtag ctggtggtac
     6601 aggtgcaggt gtctttgcag aggcaaaatc tctcaacgaa agccgtcctg aaaatgaaaa
     6661 agtttgggtt atcggtgttg accgtgacca agaagcagaa ggtaaataca cttctaaaga
     6721 tggcaaagaa tcaaactttg ttcttgtatc tactttgaaa caagttggta caactgtaaa
     6781 agatattgct aacaaggcag aaaaaggaga attccctggc ggtcaagtga tcgtttactc
     6841 attgaaggat aaaggggttg acttggcagt aacaaacctt tcagaagaag gtaaaaaagc
     6901 tgtcgaagat gcaaaagcta aaatccttga tggaagcgta aaagttcctg aaaaataatg
     6961 gatggaagtc atttcttagg aagcggccaa gggccgcttt tttaagagtt gagacaaagt
     7021 cattttgtct cagtaaagct tgctactaga caaactagca agttttattg aaataaaata
     7081 agactctgaa aggaagagca catggcacac gaaaatgtca ttgagatgcg tgatattacc
     7141 aaggtgtttg gtggatttgt tgccaacgac aaaatcaact tgcacctacg aaaaggtgaa
     7201 attcatgcac ttttaggaga aaatggggct ggtaagtcca cgctaatgaa catgttagca
     7261 ggccttcttg aaccaactag tggtgaaatc gcggtcaacg gtcaagttgt caatctcgac
     7321 tccccatcta aagcagctag cttgggaatc gggatggttc accagcactt tatgttggtt
     7381 gaagccttca cagtggctga aaacatcatt ttaggtagtg aattgactaa aaatggtgtg
     7441 ctagatatcg ctggagctag caaagaaatc aaggctcttt ctgaacgtta tggcttagct
     7501 gttgaccctt ctgccaaggt agcagatatc tcagttggag cccaacaacg tgtagaaatt
     7561 ttaaaaacac tttatcgggg ggctgatatc cttatctttg acgaaccaac ggctgttttg
     7621 actccatcag aaattgatga gttgatggct attatgaaaa atcttgtcaa agaaggaaaa
     7681 tcaattatct tgattaccca caaattggat gaaattcgag cagtttctga ccgtgttaca
     7741 gttatccgtc gtgggaaatc aattgaaacc gttgaaattg caggggctac caatgctgat
     7801 ttggcggaaa tgatggtagg acgttctgtt tcctttaaaa cagagaagca agcctctaaa
     7861 ccaaaagaag tggttttgtc tatcaaagat ttggtggtca atgaaaaccg tggtgttcca
     7921 gctgttaaaa atctgtcctt ggatgttcgt gctggagaga ttgttggtat tgcggggatt
     7981 gatggaaatg gtcagtctga actgattcaa gccattacag gtcttcgtaa ggttgaatct
     8041 ggtagcattg agctaaaagg agattcaatt gtaggcttgc acccacgtca gattacagaa
     8101 ctaagtgttg ggcacgttcc agaagaccgt caccgtgatg gcttgatttt ggaaatgatg
     8161 atatctgaaa atattgccct tcaaacctac tataaagaac cacatagtaa aaatggaatt
     8221 ttgaattatt caaatattac ttcttatgct aaaaagctga tggaagagtt tgatgttcgc
     8281 gctgccagtg aattagttcc tgcagctgca ctctcaggag gaaatcaaca aaaagcaatt
     8341 attgctcgtg aaattgatcg agatcctgat ctccttatcg ttagccagcc aactcgtggg
     8401 ttggatgtcg gtgccattga gtatatccac aaacgcttga ttgaagagcg tgataatggc
     8461 aaggctgtcc ttgttgtcag ctttgaattg gatgagattt taaacgtctc agaccgtatt
     8521 gccgttatcc acgatggtaa gattcaaggt attgtatcac cagaaacaac caataaacaa
     8581 gaacttggtg tcttgatggc tggtggaaac ttgggaaagg agaagagtga tgtctaaaaa
     8641 attacaacaa atttcggttc ccttgatttc tgtatttcta ggaattttac tcggagccat
     8701 tgtcatgtgg atcttcggtt atgatgctat ttggggctac gaagaattgt tctatacagc
     8761 ctttggcagt ctgcgtggga ttggagaaat cttccgtgct atgggtcctc tggtcttgat
     8821 tggtcttggt tttgcggttg ccagtcgagc tggtttcttt aacgtcggac ttcctggtca
     8881 ggctttggca ggttggattc tcagtggttg gtttgcgctg tcgcatccag atatgccccg
     8941 tcccttgatg attctagcaa ccatcgtgat tgccttgatt gctggtggga ttgtcggagc
     9001 gattccaggt attcttaggg cctatctagg gacgtcagag gttattgtaa ccatcatgat
     9061 gaactacatt gtcttgtatg tagggaatgc ctttatccat gctttcccta aagacttcat
     9121 gcaaagtaca gattcgacca ttcgtgttgg ggctaatgca acctatcaga caccttggtt
     9181 ggctgagttg actggtaact cacggatgaa tattggtatt ttctttgcca tcattgccgt
     9241 tgcagttatt tggttcatgc tcaagaaaac aactcttggt tttgaaatcc gtgcagttgg
     9301 tcttaatcca catgcttcag aatatgctgg tatttctgcc aagcggacta ttatcctatc
     9361 tatgattatt tcaggtgcct tggcaggtct tggtggagct gttgaaggtt tgggaacctt
     9421 ccagaacgtc tatgttcaag gttcgtcatt agctatcgga tttaacggaa tggcggttag
     9481 tttgcttgcg gccaactcac caattggtat actctttgca gccttcctat ttggcgttct
     9541 ccaagttggg gctcctggta tgaatgcggc gcaggtacca tctgagcttg tcagcattgt
     9601 aacagcgtct attatcttct ttgtcagtgt tcattacctt atcgaacgct ttgtcaaacc
     9661 gaaaaaacaa gttaaaggag gtaagtaaag atgtctatta taaccttgct ccccctcttg
     9721 gtgtcttcta tgctgattta ctcagcacct ctcatcttta caagtatcgg tggtgttttc
     9781 tctgaacgtg gtggtgtggt aaacgttggc cttgaaggaa ttatggttat gggtgccttt
     9841 tctggagttg tctttaacct tgaatttgca gaacaatttg gagcagcaac tccatggcta
     9901 tccttgcttg tagcaggatt ggttggtagt gttttctcta tcatccacgc agcagcgacg
     9961 gttcatttcc gtgcagacca tgttgtcagc ggtacggtat tgaacttgat ggcgcctgcc
    10021 ttggctgttt tcttagttaa agttctttat aacaaaggac aaaccgacaa cctaagtcaa
    10081 acttttggac gctttgattt cccagtcttg gcaaatatcc cagtgattgg tgatatcttc
    10141 ttcaagtcaa ctagtctact tggttatctg gcgattgcct tctcattcct tgcttggttt
    10201 attctcttta agactcaatt tggtcttcgt ctccgctctg tcggtgaaca tcctcaagca
    10261 gcggatacct tgggaatcaa cgtctacaag atgagatatt tagggattat tatttcaggt
    10321 tttctaggtg gaattggcgg agcgatttat gcgcaatcaa tctcagttaa cttctcagtg
    10381 acaactattg ttggacctgg atttatcgcc cttgctgcga tgatctttgg gaaatggaat
    10441 ccaatcggtg ctatgctttc tagtctcttc tttggacttt cacaaagttt ggctgttatc
    10501 ggttctcaat tgccgttcct acaaggagtg ccagcggttt atcttcaaat tgcaccttat
    10561 gttttgacaa ttcttgtctt agcagccttc tttggaaaag cagtcgcacc aaaagcagat
    10621 ggtatcaact acatcaaatc aaaataagca tacaaaaaaa cgtcagtcca atgactgaac
    10681 tgccccccaa aagttagaca gaaaaaatct aacttttggg gtgtttttat tatgaaatta
    10741 acttatgatg ataaagttca gatctatgaa ctaagaaagc aaggatatag cttagagaag
    10801 ctttcaaata aatttgggat aaataattct aatcttaggt atatgattaa attgattgat
    10861 cgttacggaa tagagttcgt caaaaaagga aaaaatcgtt actattctcc tgatttaaaa
    10921 caagaaatga ttcataaagt ctgacatgaa ggctggacta aagatagagt ttctcttgaa
    10981 tacggtctcc caagtcgtac gatacttctt aactggctag cacaatacag gaaaaacggg
    11041 tatactattg ttgagaaaac aagagggaga gtacctaaaa tgggacgtaa gccaaaaacg
    11101 agacctgaag agaggacaga attagaacgt cttcaagcag aaaatgagta cctgagagcg
    11161 gagaatgcca tcctaaaaaa gttaagagaa ctccgattga aggaggaaaa agagaaagaa
    11221 gaaagacaga aattgttcaa gaattaatga ctgagttttc gttagatctt cttctaaaat
    11281 ccattaaact agctcgttcg acctactact atcacttgaa acagctagac aaaacagata
    11341 aggaccaaga gcttaaagct gaaattcaat ccatttttat cgaacacaag ggaaattatg
    11401 cttatcgtcg gatttattta gaactaagaa atcgtgctta tctggtaaat cataaaagag
    11461 ttcaacactt gatgaagtac tcaatttaca agctaaaatg cgacagaaac gaaaatattc
    11521 ttctcataaa ggagacgttg gcaagaaggc agagaatctc attcaaggcc aatttgaagg
    11581 ctctaaaaca atggaacagt gctacacaga tgtgactgaa tttgccattc cagtaagtac
    11641 tcaaaagctt tacttatcac cagttttaga tggctttaac agcgaaatta tcgcctataa
    11701 tctttcttgt tcgcctaatt tagaacaagt acaaacaatg ttggaacagg cattcaaaga
    11761 gaagcactat gagaatacga ttctccatag tgaccaaggc tggcaatatc aacacgattc
    11821 ttatcatcgg ttcctagaga gtaagggaat tcaagcatcc atgtcacgta agggtaacag
    11881 cccagacaat ggtatgatgg agtccttctt tgggattctg aaatcggaaa tgttttacgg
    11941 ttatgagaag tcgtttcagt cgcttaagca attggaacaa gctattgtag actatgttga
    12001 ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagccctg tgcaatacag
    12061 aactaaatcc ttcggataaa ttaattgtct aactgtttgg gggcagtaca gaactggcat
    12121 tttatttttt aggatcttga tgggttaggt tcaatcccca agggaccaaa ttttcagttt
    12181 tatttttgat acgagctata ttgtccttat gacgaatgat aatcaaacta gcaagtgcta
    12241 agataatagc gatgaagaga gagtcatagt tactcaggat aaaaccaaaa agtggaaaga
    12301 gcagaacccc gataacagct gcgatcgatg ctgtgacact agacagtgaa atcatactgc
    12361 caagatagag agctccaaag aagataatcg caaggtagag acagaagata ggcgcaaatc
    12421 cgaaaatcac tccagcactg gttgcgacag ccttaccacc tttaaatcct gcaaagatag
    12481 ggaaggtatg gccgataaca gccaaaagtc caaagatgag aggagaaacg ccttgtagat
    12541 gaaaaataat cggaagcagc gttgctaggg ttcctttgaa aaagtcaatc acaaaggttg
    12601 ccataccagc tttcttacct aaaatgcgga aggtattggt cgttccagtg ttaccagaac
    12661 catgctcgcg tagattgatt tgaaagaata cttgtccaat ccagagacca gatggaatcg
    12721 aacccagcag ataggctagg attaataaaa ttattgtaat catactccta ttatatcatg
    12781 aattgggaaa gaaaagcaga gaatctctgc tgaaattgtc acatcggaga aagaaaaatt
    12841 ttgcaaaatc cttggaaaac ctgtagaata gtaaagatga acgaatagga ggttccttgt
    12901 gtcaaaaaag gaaatcaata ttaacaatta taatgatgat gctattcagg tgctagaagg
    12961 gttggatgcg gtccgaaaac gtccagggat gtatattgga tcgaccgatg gcgctggtct
    13021 tcatcaccta gtttgggaaa tcgttgataa tgcagtcgat gaagccttgt ctgggtttgg
    13081 tgatcgtatt gatgtaacta tcaataaaga cggtagtcta acggttcaag accatggacg
    13141 tgggatgccg acaggtatgc acgctatggg aattccaact gttgaggtta tctttaccat
    13201 tcttcatgcc ggagggaaat tcggtcaagg tggctataag acatcaggtg gacttcacgg
    13261 agtgggttct tccgttgtta acgccctttc tagctggtta gaagttgaaa ttacccgtga
    13321 tggcgcagtt tacaagcaac gttttgaaaa tggtggaaaa cctgtcacga ctttgaagaa
    13381 aatcggtaca gcactcaagt ctaaaacagg caccaaagtt acttttatgc ctgacgcgac
    13441 tatcttttct acgacagatt tcaagtacaa taccatttca gagcgcctta atgaatcagc
    13501 ctttctcttg aaaaatgtga ccttgtcttt agcggacaag cgaacagatg aagcgattga
    13561 gttccactat gagaatggag tacaagattt tgtttcttat ctcaacgaag ataaggaaat
    13621 cttgacgcca gttctttact ttgaagggga agacaatggt tttcaagtgg aagtagccct
    13681 ccagtacaat gacggattct cagataacat tctatccttt gtcaataacg ttcgcaccaa
    13741 ggacggtgga acgcacgaga caggactcaa gtctgccatt accaaggtca tgaatgacta
    13801 tgcacgtaaa acaggtcttc tcaaggaaaa agataaaaac cttgaaggtt cagactatcg
    13861 tgagggacta gcggccgttc tttctatctt agttcctgaa gaacacttgc agtttgaagg
    13921 acagaccaag gataaactag gaagccccct agctcgccca gttgtggatg gaatagtggc
    13981 tgataagttg acctttttcc ttatggaaaa tggggaatta gcttctaacc tcatccgcaa
    14041 ggctatcaag gcccgtgatg ctcgtgaagc agcacgtaag gcgcgtgatg agagccgaaa
    14101 tgggaagaaa aacaagaaag ataagggctt gttgtctggg aaattgaccc cagcccaatc
    14161 taagaatcct gctaagaatg aactctatct agttgagggg gactctgccg gtggttctgc
    14221 caaacaaggt cgtgaccgca agttccaggc tattctacct cttcgtggta aggttgtcaa
    14281 tacagccaag gccaagatgg cggatatcct caaaaatgaa gagatcaata ccatgattta
    14341 taccattggt gcgggtgttg gagcagactt ctctattgaa gatgccaact atgataagat
    14401 cattatcatg accgatgcgg ataccgacgg tgcccatatc cagaccttgc tcttgacatt
    14461 tttctaccgt tacatgcgtc cgctagtcga ggcaggtcat gtctatattg ccctcccacc
    14521 tctttacaag atgtccaaag gtaaaggcaa gaaagaagaa gtggcctacg cttggacgga
    14581 cggagaacta gaagaactcc gtaaacagtt cggtaaaggc gctaccctcc aacgatacaa
    14641 aggacttggt gagatgaatg cggaccagct ctgggaaaca accatgaacc cagaaacacg
    14701 taccctcatc cgtgtcacaa ttgaagattt agcgcgcgcc gaacgccgcg tcaatgttct
    14761 catgggagat aaggtagaac cacgccgtaa atggattgaa gataatgtca agtttacgct
    14821 agaagaagcg acagtgtttt aatgaaagaa aataatatgt tagtaaactg gaaattagag
    14881 tcggatgtga atgactatgt gaaaaagcag tttgaaaatc ttggtttgaa aaaattgcag
    14941 gattattaat gaagaatctg ctatgagtgc ttatctcaaa gaggcgttta agggagcggc
    15001 taagacacaa actaagacta attttggaaa accatatttt catattgaaa aatacaaaca
    15061 ggatagtttg gttacttatc gtaactgaac acgggacgaa ttcccgtaaa atatctttta
    15121 ctgcataaaa acctactcta cattctttga aaggagttga acacgcccta gatactgtgt
    15181 gaaaaagata aattctcttg tgagtttgct tacttcaaga attttctatt ttcacttggt
    15241 attttatggg ctttgtatct tatgtctaac attcaaaaca tgtccctgga ggacatcatg
    15301 ggagagcgct ttggtcgcta ctccaagtac attattcaag accgggcttt gccagatatt
    15361 cgtgatgggt tgaagccggt tcagcgccgt attctttatt ctatgaataa ggatagcaat
    15421 acttttgaca agagctaccg taagtcggcc aagtcagtcg ggaacatcat ggggaatttc
    15481 cacccacacg gggattcttc tatctatgat gccatggttc gtatgtcaca gaactggaaa
    15541 aatcgtgaga ttctagttga aatgcacggt aataacggtt ctatggacgg agatcctcct
    15601 gcggctatgc gttatactga ggcacgtttg tctgaaattg caggctacct tcttcaggat
    15661 atcgagaaaa agacagttcc ttttgcatgg aactttgacg atacggagaa agaaccaacg
    15721 gtcttgccag cagcctttcc aaacctcttg gtcaatggtt cgactgggat ttcggctggt
    15781 tatgccacag acattcctcc ccataattta gctgaggtca tagatgttgc agtttacatg
    15841 attgaccacc caactgcaaa gattgataaa ctcatggaat tcttacctgg accagacttc
    15901 cctacagggg ctattattca gggtcgtgat gaaatcaaga aagcttatga gactgggaaa
    15961 gggcgcgtgg ttgttcgttc caagactgaa attgaaaagc taaaaggtgg taaggaacaa
    16021 atcgttatta ctgagattcc ttatgaaatc aataaggcca atctagtcaa gaaaatcgat
    16081 gatgttcgtg ttaataacaa ggtagctggg attgctgagg ttcgtgatga gtctgaccgt
    16141 gatggtcttc gtatcgctat tgaacttaag aaagacgcta atactgagct tgttctcaac
    16201 tacttattta agtacaccga cctacaaatc aactacaact ttaatatggt ggcgattgac
    16261 aatttcacac ctcgtcaggt tgggattgtt ccaatcctgt ctagctacat cgctcaccgt
    16321 cgagaagtga ttttggcgcg ttcacgcttt gacaaagaaa aggctgagaa acgtctccat
    16381 atcgtcgaag gtttgattcg tgtgatttcg attttggatg aagtcattgc tcttatccgt
    16441 gcttctgaga ataaggcgga cgccaaggaa aacctcaaag ttagctatga ttttacggaa
    16501 gaacaagctg aggctatcgt aactttgcaa ctgtaccgtt tgaccaatac cgatgtggtt
    16561 gtcttgcagg aagaagaagc agagcttcgt gagaagattg ctatgctggc ggctattatt
    16621 ggtgatgaaa ggactatgta caatctcatg aagaaagaac ttcgtgaggt caagaagaaa
    16681 tttgcaactc ctcgtttgag ttctttagaa gacactgcga aagcaattga gattgataca
    16741 gctagtctta tcgctgagga agatacctac gtcagcgtga ccaaggcagg ttacatcaag
    16801 cgtaccagtc cacgttcctt tgcggcttcc accttggaag aaattggcaa gcgtgatgat
    16861 gaccgtttga tttttgttca atctgccaag acaacccagc acctcttgat gttcacaagt
    16921 cttggaaatg tcatctacag accaatccat gagttggcag atattcgttg gaaggacatc
    16981 ggagagcatc tgagccaaac catcacaaac tttgaaacga atgaagaaat cctttatgtg
    17041 gaagtactgg atcagtttga cgatgcgaca acctactttg cagcgactcg ccttggtcaa
    17101 atcaaacggg tagagcgaaa agaattcact ccatggcgga cctatagatc taagtctgtc
    17161 aagtatgcta agctcaaaga cgatacagat cagattgtag cagtggctcc gattaaacta
    17221 gatgatgttg tcttggttag tcaaaatggt tatgccctgc gtttcaatat cgaagaggtt
    17281 ccggttgtcg gtgctaaggc agcaggtgtc aaggctatga atttgaaaga agatgatgtc
    17341 ctccaatctg gctttatctg taatacttcg tccttctacc tcttgaccca gcgtggaagc
    17401 ttgaaacgtg tttccattga ggaaattcta gcaaccagcc gtgccaaacg aggattacag
    17461 gtcttgcgtg agttgaaaaa caaaccgcat cgtgtcttct tggcaggagc agttgcagag
    17521 caaggatttg ttggcgattt cttcagtacg gaagtggatg tgaacgacca aactctgctt
    17581 gtccaatcca ataaaggaac aatctatgaa agccgattgc aagacttgaa cttgtcagaa
    17641 cgcactagca atggaagctt catttctgac acgatttcag atgaagaagt ttttgacgct
    17701 tatcttcagg aagtagttac tgaagataaa taagtgaaat gaagaatcag ttctaagagc
    17761 tggtttttat tggagaaatt ttctgaaaat tacaaaatat acttgctatt ttagaaaaat
    17821 agtgtagaat ataagaaata ggtttttaga ataaggagtg gaatatgaca gtaacgattg
    17881 attgggaaaa cctcggtttt tcctatatga aattacctta tcgctatctt gctcatttca
    17941 aaaatggaca atgggatcaa ggagagctta cagaggatgc aactttgcat atttcagagt
    18001 cttctccaag tcttcactat ggacaacaag catttgaagg tttgaaagct tatcgtacta
    18061 aggatggcag tgttcaactg ttccgtcctg atgaaaatgc taaacgcctg caacgtacat
    18121 gtgaccgtct cttgatgcca caagttccga cagacatgtt tgtagaagct tgtaaagcag
    18181 ttgtccgtgc gaatgaagaa tacgtaccac catacggaat aggtggaacc ttatatcttc
    18241 gccctctttt gattggtgtc ggagatatta tcggggtaaa accggcagaa gagtacattt
    18301 tcaccatctt tgctatgcca gttggaaatt actttaaagg tggtttggtc ccaaccaact
    18361 tcttgattca ggatgagtac gaccgtgcag caccaaatgg tacaggtgcg gctaaggttg
    18421 gtggaaacta tgctgcaagt ctcttaccag gaaaaatggc caattcacgt catttctcag
    18481 atgttatcta tctggaccca tcaactcata caaagattga agaagtcgga tcagctaact
    18541 tctttggaat tacagctgat aatgaatttg taacaccatt gagtccatct atcttgccat
    18601 ctattaccaa gtattccttg ctttatttgg cagaacaccg cttgggatta actcctattg
    18661 agggtgatgt tccaattgat aatcttgacc gttttgtaga ggcaggtgcc tgtggtacag
    18721 cagcggttat ttctccaatt ggaggtattc aacatggtga tgatttccat gtattctata
    18781 gtgaaacaga agtaggtcct gtgacgcgta aattatataa tgaattgacg ggtattcagt
    18841 ttggcgatat tgaagcgcca gaaggttgga ttgtaaaagt agattaaaat aaaccgaagg
    18901 agatttttta tgaaatagaa aaagtggctc ttaacagcag gagtggtcct gagcacgtca
    18961 gctattttag tggcttgtgg aaaaactgat aaagaagccg atgcaccgac aacattttct
    19021 tatgtctatg cagtagatcc agcatcattg ggctacagta tagcgactcg aacatcgacg
    19081 acagacgtta ttggaaatgt tattgatggt ttgatggaaa atgataaata cggcaatgtt
    19141 gctccttctc aaaaagacta tgatttgaat agtacaggat gggctccaag ctatcaagat
    19201 ccagcgtctt acttgaatat tatggatcca aaatctggtt ttgccatgaa acaccttggt
    19261 attacgaaag gaaaagataa ggatgttgta gctaaacctg gtttggataa atataagaaa
    19321 ttgttagaag atgctgtttc tgagaccact gacctagaga agagatatga aaaatatgcc
    19381 aaagctcaag cttggtcgac agatagttca ttattgatgc caacagcttc atctggtggt
    19441 tctccagttg taagtaacgt agtaccattc tcaaaaccat actcacaagt tggtattaag
    19501 ggggatccat atatctttaa aggaatgaaa ttgcaaaaag atattgttac aacaaaagaa
    19561 tataacgagg tttttaaaaa atggcaaata ccaaaaagaa ctagaaaaat acattaaata
    19621 aggaatggta ttgatcttga taaaattttt aaaatactgt cattttgaat ataaaggagt
    19681 ttgatatgga gtggattaga ttaataggaa tagcaatcat tgttgtgggt tttattttaa
    19741 aatttgatac aattgcaaca gtagtcttag ctggtttggt tacagcttta gtttcaggtg
    19801 tttctctcgt tgaatttttg gagattttgg gaaaagaatt tagcaatcag cgagtgctca
    19861 cgatttttat ggttaccttg cctcttgtgg ggctgtcaga aacctttgga ctcaagcaac
    19921 gatcaatcga tttgattcga aagattaaag gtctgacagt tggaaacttc tatacagttt
    19981 atttctttat tcgagagtta gctggtttct tttcaattcg tctaggagga caccctcagt
    20041 ttgtcagacc tttggttcaa cctatgggag aagcagctgc agagtctcaa ttaggtagaa
    20101 agttaacaga ggttgaagat gagacaataa aagcgcgtgc ggctgcgaat gaaaattttg
    20161 gaaatttctt tgctcaaaat acgtttgtag gtgctggggg agtcctcttg atagggggaa
    20221 cattagatca gttaggctat gaaagcaatt atgcagggat tgcttctaca tctattattg
    20281 ttgctgttat aacacttatt gtagtgggga tttacaatta tttatttgat aaaaaattga
    20341 tatcaaaaaa gactagggga ggagaacaaa aatgacagag ttggcaaagc aactattaga
    20401 gttgacctat attgtgattg gttgtcaatt tctccataca gcctattgta gttataaaga
    20461 taaaacaaac ccagttcgac ttgggacatc tgcattttgg actctattgt ctattacgtt
    20521 tataggtggt tcctatatgc caaatatgag tattggtatt attgtaatcc tattatcgct
    20581 gttaacattg tttaagcaag tccgtatcgg aaccttgcca tccttagatg aaatgaaagc
    20641 caatattgaa tctaacaggt tgaaaaataa aatttttatt ccagttatgc tgatggcaat
    20701 acttgcgttg gtcttagcgc aaatgattcc agaatttagc aagatttcga ttagccttgc
    20761 cgccttgttt gctacaattt ctgttcttgt gattaccaat agtcacccta agagtctgtt
    20821 atcagaaaat aatcgaatga ctcagcaagt ttcaacaagt ggtattgttc ctcaattatt
    20881 aggggctttg ggggctattt ttactgtagc aggtgttggt gatgttatct ctcatctgat
    20941 tagcggtatt gttccttcag atagtcgctt tataggagtt ttggcctatg ttcttggaat
    21001 ggttctattc acaatgatta tgggaaatgc ttttgcagca ttcaccgtta ttacagcagg
    21061 tgttggagtt ccctttgtat ttgctctggg agctaatcca attgtggctg gtgctcttgc
    21121 catgacagca ggttattgtg ggaccttatt gaccccaatg gctgctaatt ttaacgctct
    21181 accagcagca ttgatggata tgaaagatca gaatggcgtt ataaaggctc aagcaggtgt
    21241 tgctctagta atgattgtta ttcacatatt cttaatgtac tttctcgcat tttagtaaag
    21301 gaaaataaaa tgaaaatatt ggttacaggt tttaatcctt ttggaggtga aaagattaat
    21361 ccagctttgg aggctgtaaa attattacca tctgagatta atggggctga agttcgctgg
    21421 gtagaaattc caacggtttt ttataagtcg tcagaagttt tagaggcaga aatattacga
    21481 tatcaaccag atgctgtact ttgtattgga caagcaggcg gcaggaccgg cttaacacct
    21541 gaacgagtgg ctattaatca agatgatgct cgcatacctg ataacgaagg caatcaacca
    21601 attgatacac cgattcgtat tgatggagca tcggcctatt ttagtagttt acctatcaaa
    21661 gcgatggtac aagctatcaa aaaacaggga cttccggcag ttgtatccaa tagtgcagga
    21721 acctttgttt gcaatcattt gatgtaccaa gctctttatt tagtggataa aaaattccct
    21781 aatatgagag caggtttcat gcatattcca tatatgatgg aacaagtagt aaataagccg
    21841 aatactgcag gaatgagtct atgtgatatt gtaagaggca tagaggtagc tattgaaact
    21901 attgtagact acaaagataa ggatttgcag ttagtaggcg gtgagactca ctgataacct
    21961 aaaaaggata gtcaattatg cttgtttact aactattaac tatgctaaat cgattgaggt
    22021 tgtttacata aaactctata tcagagaagc ctgatataga gttttttctt gctagtttta
    22081 ggattttctt gtaaaataga aaaagtgaag agaggtatga aatgagcaag aaagataaaa
    22141 aaatcgaaat tcaagtagcg gatgccaaag ttaatgttgg taaagacagt tttgaaggtt
    22201 atacattgac tatcggtaaa aaagttatcg gagaaattgc cgaattagac ggacaatttg
    22261 ccattataaa gaatgggaat gtcgatagtt tttataaaaa attggaaaaa gctgtggaaa
    22321 ttttgattga aaattataat ttagcaaaat aagtcttgtt tttttgaaat tttcatgata
    22381 taatagtcca tgttgattgt aggagagata gcgaagaggc taaacgcggc ggactgtaaa
    22441 tccgctcctt cgggttcggg ggttcgaatc cctctctctc catttcatta atggggtata
    22501 gccaagcggt aaggcaaggg actttgactc cctcatgcgt tggttcgaat ccagctaccc
    22561 cagttcttag gtaataatca agatagaaag caaaatatct tagggtattt tatttttata
    22621 attgaaagac gtgaatgata tgaacatgtc cttgcgggtg cttaggaaaa aaattataag
    22681 tatgtcaagt ttaagaaaaa cttgattgtt ggaggatttt ttagatgaac gaatttgaag
    22741 atttgctaaa tagcgttagt caagttgaga ctggtgatgt tgttagtgct gaagtattga
    22801 cagttgatgc gactcaagct aacgttgcaa tctctggaac tggtgttgaa ggtgtcttga
    22861 ctcttcgcga attgacaaac gatcgtgatg cagatatcaa tgactttgtt aaagtaggag
    22921 aagtattgga tgttcttgta cttcgtcaag tagttggtaa agatactgat acagttacat
    22981 accttgtatc taaaaaacgc cttgaagctc gcaaagcatg ggacaaactt gttggtcgcg
    23041 aagaagaagt tgttactgtt aaaggaacgc gtgccgttaa aggtggactt tcagtagaat
    23101 ttgaaggtgt tcgtggattt atcccagctt caatgttgga tactcgtttc gtacgtaacg
    23161 ctgagcgttt tgtaggtcaa gaatttgata ctaaaatcaa agaagttaac gctaaagaaa
    23221 accgcttcat cctttcacgt cgtgaagttg ttgaagcagc tactgcagca gctcgcgctg
    23281 aagtattcgg taaattggct gttggtgatg ttgtaactgg taaagttgct cgtatcacaa
    23341 gcttcggcgc tttcatcgac cttggtggtg ttgacggatt ggttcacttg actgaattgt
    23401 cacatgaacg taacgtatca ccaaaatcag ttgtaactgt tggtgaagaa attgaagtga
    23461 aaatccttga tcttaacgaa gaagaaggac gtgtatcact ttcacttaaa gcaacagtac
    23521 caggaccatg ggatggcgtt gagcaaaaat tggctaaagg tgatgtagta gaaggaacag
    23581 ttaaacgttt gactgacttc ggtgcatttg ttgaagtatt gccaggtatc gatggacttg
    23641 ttcacgtatc acaaatttca cacaaacgga ttgaaaatcc aaaagaagct cttaaagttg
    23701 gtcaagaagt tcaagttaaa gttcttgaag ttaacgcaga tgcagaacgc gtgtcacttt
    23761 ctattaaagc tcttgaagaa cgtccagccc aagaagaagg acaaaaagaa gaaaaacgtg
    23821 ctgctcgtcc acgtcgtcca agacgtcaag aaaagcgtga tttcgaactt ccagaaacac
    23881 aaacaggatt ttcaatggct gatttgtttg gtgatatcga actttaatca aattgaaaat
    23941 tcacaaaatc ctttgtttac taaacaaggg atttttctgg ctctttgtca actgtagtgg
    24001 gttgaagtca gctaagcttg agaaaggaca aatttcgtcc tttctttttt gatgttcaaa
    24061 gcgataaaaa tcc
//
LOCUS       DAVEHY010000032        23096 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVEHY010000032 DAVEHY010000000
VERSION     DAVEHY010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.032"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..435
                     /locus_tag="VUZ44_001581"
     CDS             <1..435
                     /locus_tag="VUZ44_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU0320462.1"
                     /translation="SNGAMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGD
                     MATGWAKVNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEAS
                     GAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            836..1957
                     /gene="mnmA"
                     /locus_tag="VUZ44_001582"
     CDS             836..1957
                     /gene="mnmA"
                     /locus_tag="VUZ44_001582"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU0320463.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFT
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2098..2553
                     /locus_tag="VUZ44_001583"
     CDS             2098..2553
                     /locus_tag="VUZ44_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU0320464.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKSQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2563..4476
                     /gene="mnmG"
                     /locus_tag="VUZ44_001584"
     CDS             2563..4476
                     /gene="mnmG"
                     /locus_tag="VUZ44_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU0320465.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQDNLTLRQTMIDEILVEDGKIVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMDFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4683..4775)
                     /locus_tag="VUZ44_001585"
                     /pseudo
     CDS             complement(4683..4775)
                     /locus_tag="VUZ44_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4829..6508)
                     /locus_tag="VUZ44_001586"
     CDS             complement(4829..6508)
                     /locus_tag="VUZ44_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU0320466.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAIKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6510..6743)
                     /locus_tag="VUZ44_001587"
     CDS             complement(6510..6743)
                     /locus_tag="VUZ44_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU0320467.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(7561..7713)
                     /gene="cibB"
                     /locus_tag="VUZ44_001588"
     CDS             complement(7561..7713)
                     /gene="cibB"
                     /locus_tag="VUZ44_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU0320468.1"
                     /translation="MMKDLNNYREISNKELQEIKGDFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7716..7902)
                     /gene="cibA"
                     /locus_tag="VUZ44_001589"
                     /pseudo
     CDS             complement(7716..7902)
                     /gene="cibA"
                     /locus_tag="VUZ44_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
     gene            8079..8762
                     /gene="tsaB"
                     /locus_tag="VUZ44_001590"
     CDS             8079..8762
                     /gene="tsaB"
                     /locus_tag="VUZ44_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU0320469.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVAPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEAESLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8759..9196
                     /gene="rimI"
                     /locus_tag="VUZ44_001591"
     CDS             8759..9196
                     /gene="rimI"
                     /locus_tag="VUZ44_001591"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU0320470.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLISPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9186..10196
                     /gene="tsaD"
                     /locus_tag="VUZ44_001592"
     CDS             9186..10196
                     /gene="tsaD"
                     /locus_tag="VUZ44_001592"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU0320471.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10236..11542)
                     /locus_tag="VUZ44_001593"
                     /pseudo
     CDS             complement(10236..11542)
                     /locus_tag="VUZ44_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11818..12169)
                     /locus_tag="VUZ44_001594"
                     /pseudo
     CDS             complement(11818..12169)
                     /locus_tag="VUZ44_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12276..12569)
                     /locus_tag="VUZ44_001595"
                     /pseudo
     CDS             complement(12276..12569)
                     /locus_tag="VUZ44_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12812..14017
                     /locus_tag="VUZ44_001596"
     CDS             12812..14017
                     /locus_tag="VUZ44_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU0320472.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYD
                     ELLEKSSHG"
     gene            14010..14963
                     /locus_tag="VUZ44_001597"
     CDS             14010..14963
                     /locus_tag="VUZ44_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0320473.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            14973..16589
                     /locus_tag="VUZ44_001598"
     CDS             14973..16589
                     /locus_tag="VUZ44_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320474.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16849..17277
                     /locus_tag="VUZ44_001599"
     CDS             16849..17277
                     /locus_tag="VUZ44_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320475.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17289..18037
                     /locus_tag="VUZ44_001600"
                     /pseudo
     CDS             17289..18037
                     /locus_tag="VUZ44_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
     gene            18050..19222
                     /locus_tag="VUZ44_001601"
     CDS             18050..19222
                     /locus_tag="VUZ44_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU0320476.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            19617..20480
                     /locus_tag="VUZ44_001602"
     CDS             19617..20480
                     /locus_tag="VUZ44_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU0320477.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQGQMAETYRRLNAIVIKNALHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGNNQKEIENFIQSLQVLENPQLTSLFE
                     LRFQQYKELID"
     gene            20771..20968
                     /locus_tag="VUZ44_001603"
     CDS             20771..20968
                     /locus_tag="VUZ44_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU0320478.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            21036..21701
                     /locus_tag="VUZ44_001604"
     CDS             21036..21701
                     /locus_tag="VUZ44_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0320479.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            21773..22999
                     /locus_tag="VUZ44_001605"
     CDS             21773..22999
                     /locus_tag="VUZ44_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU0320480.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLVSDTLSAFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7032 a         3932 c         4931 g         7201 t
ORIGIN      
        1 agcaatggcg ctatggcgac aggctggctc caatacaatg gctcatggta ctacctcaac
       61 gctaatggtg atatggcgac aggctggctc caatacaacg gttcatggta ttacctcaac
      121 gctaatggtg atatggcgac aggatgggct aaagtcaacg gttcatggta ctacctaaac
      181 gctaacggtg ctatggctac aggttgggct aaagtcaacg gttcatggta ttacctcaac
      241 gctaacggtt caatggcaac aggttgggtg aaagatggag atacctggta ctatcttgaa
      301 gcatcaggtg ctatgaaagc aagccaatgg ttcaaagtat cagataaatg gtactatgtc
      361 aatggcttag gtgcccttgc agtcaacaca actgtagatg gctatgaagt caatgccaat
      421 ggtgaatggg tttaagccga ttaaattaaa tcatgttaag aacatttgac attttaattt
      481 tgaaacaaag ataaggttcg attgaataga tttatgttcg tattctttag gtacctgtct
      541 tatgatttca ggaaatgtca ttaaaaaaac gactcctttt ctctaacttg gaaaatagat
      601 tagagaaaat gggttgtttt atttattata gttatttgaa tgaagataag aagaaggtat
      661 attcacatca ttcacataat ctgtatattg actataagtt ttaaaaaaca atttttaagc
      721 tcttccttgt cttctctaac caagcgtgtt ataatgaata ctgctcaagc gaccttcaat
      781 cgtgaagcac acacgacctt caatcgtgaa taaacgaata gatgggagac ttaccatgag
      841 tgataactct aaaacacgtg ttgtcgtggg gatgagtggt ggtgttgatt cgtcggtgac
      901 ggctcttttg ctcaaggagc agggctacga tgtgatcggt atcttcatga agaactggga
      961 tgacacagat gaaaacggcg tctgtacggc gaccgaagat tacaaggatg tggttgcggt
     1021 ggcagaccag attggcattc cctactactc tgtcaatttt gaaaaagagt actgggaccg
     1081 cgtttttgag tatttcctag cggaataccg tgcagggcgc acgccaaatc cggacgttat
     1141 gtgcaacaag gaaatcaagt tcaaggcctt tttggactat gctatgacct tgggggcaga
     1201 ctatgtagcg actgggcatt atgctcgagt ggtgcgtgat gaggatggta ccgttcacat
     1261 gcttcgtggc gtggacaatg gcaaggatca gacctatttc ctcagccaac tttcgcaaga
     1321 acaacttcaa aaaaccatgt tcccactagg acatttggaa aagcctgaag ttcgaaaact
     1381 agcagaagaa gcaggtcttt cgactgctaa gaagaaagac tcgacaggga tttgctttat
     1441 cggagaaaag aactttaaaa actttctcag caactacctg ccagctcagc ctggccgcat
     1501 gatgactgtg gatggtcgcg atatgggcga gcatgcaggt cttatgtact atacgattgg
     1561 tcagcgtggc ggactcggta tcggtgggca acacggtggt gacaatgccc cttggttcgt
     1621 tgtcggaaaa gatctaagca agaatattct ctatgtagga caaggattct accatgattc
     1681 gctcatgtca actagcctag aagccagtca agtccacttt actcgtgaaa tgccagaaga
     1741 gtttacgcta gaatgtacgg ctaaattccg ttaccgtcag cctgattcta aggtgaccgt
     1801 ccatgtcaaa ggagacaagg cagaggttat ttttacagaa ccacaacgcg cgattacacc
     1861 aggacaggca gttgtctttt acgatggcga agagtgtcta ggtggcggtt tgattgacaa
     1921 tgcttaccgc gatggacaag tttgtcagta catttagatt gacaaatttt ctcaatttgc
     1981 tacaataata acagcaatag aaatgatggt caaagctcat ggatgttgca ggcttttttg
     2041 tcctgcactt ctttgtagtt ttgactgttt ttgtgtcgtt taagggaaag gacaagaatg
     2101 actcaacaag actttcggac aaaagtagat aatacggttt ttggtgttcg ggcgacagct
     2161 ttgattcttc aaaatcgcaa gcttctagtc accaaagaca agggcaagta ttacactatc
     2221 ggcggtgcga ttcaagttaa cgaaaaaaca gaagacgcgg tagtccgtga agtgaaggaa
     2281 gaactgggtg ttaaatctca agctgggcag ctagcttttg tggttgaaaa tcgttttgaa
     2341 gtggacggcg tttcctatca caatatcgag tttcattatc tggtggattt gcttgaagat
     2401 gccccgttga ccatgcagga agatgagaaa aggcagccct gtgagtggat tgacttggat
     2461 aagcttgagg atatccagct agttccagcc tttttaaaaa cagccctacc agattgggaa
     2521 ggccaactaa gacacattca tcttgaggaa taggagagaa acatgactta tcattttact
     2581 gaagaatacg atattattgt aattggtgcg ggacacgctg gggttgaggc ttccttggcc
     2641 gctagccgta tgggctgtaa ggttctactt gcgaccatca atattgaaat gctggctttc
     2701 atgccttgta atccttctat cggtggttct gccaagggga ttgtcgtacg tgaagttgat
     2761 gccctcggtg gcgagatggc caagaccatt gacaagactt acatccagat gaagatgctc
     2821 aacacaggga agggtcctgc tgttcgtgcc cttcgtgcgc aggctgataa ggaactttac
     2881 tctaaggaaa tgcgcaagac ggttgaaaac caagacaatc tgacccttcg tcagaccatg
     2941 attgatgaga ttttggtgga agacggcaag attgtcggtg tgcgtacagc cacccatcaa
     3001 gaatatgctg ctaaggctgt tattgtgacg acagggactg ctctccgtgg ggaaattatt
     3061 atcggagacc tcaagtactc atcaggacct aaccacagct tggcttctat taacctagct
     3121 gacaatctca aggaactggg cctcgaaatc ggtcgtttca agacaggaac ccctccacgt
     3181 gtcaaggctt cttctatcaa ctacgatgtg accgagattc agccaggaga cgaagcgcct
     3241 aatcatttct catacacttc acgtgatgag gattatgtca aagatcaagt gccatgctgg
     3301 ttgacctata ccaatggtac cagtcatgag attatccaaa acaacctcca ccgtgcgcct
     3361 atgtttacag gtgtggtcaa gggagtgggg cctcgttact gtccgtcgat tgaagacaag
     3421 attgtgcgct ttgcggacaa ggaacgtcac caactcttcc ttgagccaga agggcgcaat
     3481 actgaggaag tctatgtgca aggactttca accagtctgc ctgaggatgt ccagcgtgac
     3541 ttggttcatt ccatcaaagg tttggaaaat gcagagatga tgcggacagg ttatgctatt
     3601 gagtatgata tggtcttgcc tcatcagctg cgtgcgactt tggaaaccaa gaaaatctca
     3661 ggtctcttca ctgctggtca gacaaatgga acgtcaggtt acgaagaggc agcaggccaa
     3721 gggattatcg cgggtatcaa tgcggctctg aaaatccaag gcaagcctga gttgattttg
     3781 aagcgcagtg acggctatat cggggtgatg attgatgact tggtgaccaa gggaaccatt
     3841 gaaccctacc gtctcttgac cagtcgtgct gaataccgtc tcattcttcg ccatgataat
     3901 gctgatatgc gcttgactga gatgggacgc gagattggcc ttgtggacga tgaacgctgg
     3961 gctcgttttg aaatcaagaa aaatcaattt gacaatgaga tgaaacgcct agacagtatc
     4021 aaactcaagc cagtcaagga aaccaatgcc aaggttgagg aaatggactt caagccgttg
     4081 acagatgcgg tgacagccaa ggaattcctt cgccgtccag aagtttctta ccaagatgtg
     4141 gtggccttca tcggaccagc tgcagaagac ttggatgaca agattatcga attgattgaa
     4201 acagaaatca agtatgaagg ctatatttcc aaagccatgg accaggttgc caagatgaaa
     4261 cgcatggaag aaaaacgcat tccggccaat atcgactggg atgacattga ttctatcgca
     4321 accgaagccc gtcagaagtt caaactcatc aatccagaaa ccatcggcca agccagccgt
     4381 atttcgggag taaacccagc agatatttct attttgatgg tgtatctgga aggtaaaaat
     4441 cgtagtattt ctaaaactct tcaaaaatca aaatgatacg tcgtcggctt cttacgaatg
     4501 agttcaaagc ttggctttga ttcatctcca gcctcccata gtttcccgaa ctatgggagc
     4561 taactcaagt tatgctttcg cttagccttc tagtctgatt tcgattttta ttgatactct
     4621 tcgaaaatct cttcaaaccg cgtcaacgtc gccttgccgt aggtatggct actgacttcg
     4681 tcagttctat ctacaacctc aaagcagtgc tttgagcaac ctacggctag cttcctagtt
     4741 tgctctttga ttttcattga gtatgagttt taatctcaaa agaaagcata gagaaaaaca
     4801 gctccgagga cggggctgtt ttcttgcttt attcttcatc tggtgtgagg atcatcggga
     4861 tgatgatcgg ttcacgttcg gtattttcat agaggaaggg gcgaatagcg ttgacaatgg
     4921 caccattgac agattgcacg ctagcatcct tatttttcag tgcgatacga atggcattga
     4981 agaggatacg ctggctttgg cgaatcaagt ctccagactc tctcatgtag acaaagcctc
     5041 ggctgaggat atctgggcca gacagaatca tctgcgattt gaagtcaaca gttgcgactg
     5101 ctagaacgac accgtcttca gatagatcgc gacgatcttt gaggacagct gcgccaattt
     5161 caccgatacg atttccatcg acatagatat cttgggcgtt gaaatgacct gcgatacgag
     5221 ctgagtcagc agtaagggca agcacatcgc cattgctcat gataaagata ttgtccttct
     5281 caacaccagt atccactgct agtccagcgt ggactttttg catgcggtat tcaccgtgga
     5341 caggcatgaa gtattttggc ttaatcaagc agagcatgag tttttgctct tgctgaccac
     5401 cgtgtccaga tgtatggata ttgttcactt taccgtggat aacttcgaca ccagcttcag
     5461 aaatgatgtt aatcagcttg ttgacgctag tagtgtttcc agggatggga ctagaagaga
     5521 agataacggt atcacctggt tgtaattgta cttgacggtg ggttccgttg gcgatacgag
     5581 agagggctgc cataggctca ccctgactac ctgtacagag gataagaact tctcctgcag
     5641 gataatcttt gatttcattt ggctcgataa aggttccctt aggagctttg atgtagccaa
     5701 gatcgattcc gttgacaatg gccttttcca tagaacgacc aaagaccgca atcttgcgtc
     5761 cagtcttaat agcagcttct gttgcctgct ggagacggaa gatatttgag gcaaaggatg
     5821 caaagatgat acgtccttca ataccttgga taatcttcat aatggactga ccaacgactt
     5881 tttcagagtt ggtaaaggtt ggtacttccg catttgtcga gtcagacagg agacagagca
     5941 cgccttcttc accaagggca gccatacgat gcaagtccgc aggttctcca actggagtaa
     6001 agtcgaactt aaagtcaccc gtacagacga ttttcccttg aggagtatga atgacaatcc
     6061 ccaaaggctc tggaatagag tgagtcgttc taaagaaagt tgccttgaga tttttaaagg
     6121 tcaactcggt gttgtggttg atttcgtaaa gtttggcgtt gcgcaagagg ccgtgttctt
     6181 cgagtttccc acggatcaaa gccaaggcaa gcggtccagc gtagataggg acatttgctt
     6241 gcttgagtag gaacggaatc ccaccaatgt ggtcctcgtg tccgtgtgtg attaaaacag
     6301 ccttgacgcg gtcgatattg tccacgatgt aagagtagtc aggaatgaca tagtcgatac
     6361 caagcaagtc atcttctggg aatttaatcc cagcatcgac gatgataatc tcgtcttggt
     6421 attcaattcc gtaagtgttt ttcccgattt ctcctagacc accgatggca aaaacgccga
     6481 cttcttcagg tttaagagtg taggccatat tagaactccg taatttcgaa ggcgccagtt
     6541 tctttttcgt aatcgagcaa tttgtcagac aagagttcga tatactcgat attgtactct
     6601 gggcgatttt cttcgacaag ttggcgagca gtgatacggc cctcaagttc tgagctggca
     6661 tcgatgtcta ggtaaagcgt gcgtgttgtt tcacggcgtg ggctacgttc ttttgtttct
     6721 tgataaaaaa ctttgtaaat catatagttc ctttctattt acaggtcagc ttattccaaa
     6781 cttttagcag atatttgctt gatttcattc cattttgtgt ctagattgac cttgattcgt
     6841 tacaattatt tcaattatac cacaaaatga aaaattagta aaagacggaa acgagaaagt
     6901 taggggacga tttctttggt aagcgtttgc aaaaataaag aaaatgtatt atgttgataa
     6961 cggaagtgaa atttattgct tgtcataatt ccatatagat tttaagtcaa ggaggttgcc
     7021 ctatgtataa cttatttgct tttgctatcg gagctcgctt ggtagctttt attgtttttg
     7081 ttgcttgcgt ttatgcgggg aatcttctat ttgccaaact ggaacgatga caaaccaagt
     7141 tcttgtggaa aattaccttt gtgactctct actcgctttt tctcctcctc gtgacctatg
     7201 tcgtttggtt tgtattttac tttggattaa atgcttagat gccctgctta tgctggggtt
     7261 ttttgtttgg ggatgtagag atagtagatt tacgacacga aaattccacc ccatctatca
     7321 agatgaggtg gtctttgcat ttttctaaca tgacatgaca atggaatttt caaagcttat
     7381 tatttttatg ggagtcattg ttctgctcaa aaatagagtt gaagcataaa aataaaacaa
     7441 tacaaacaga taaatcgaat ggtaaaggga tagtagtaat gttcaaatca ttgagaatgc
     7501 tgagcaaact gtaagagatg aagacaataa aatttatcct tctaaaaatg tgtttcttat
     7561 ctagcatgac ttaccaaact ttttacgaag gtcttttcca atggtataac ctgccataaa
     7621 taaagcgata ccaacaccta caccaaagtc acccttgatt tcttgcaatt ccttattaga
     7681 aatttcacga tagttgttca aatctttcat catagttaat ctcctcctaa aaaataacca
     7741 gctgccaaac cagaacctat aagtgctgtt ccacctgcaa tagccttcca agatactgct
     7801 actccaaaga taaccaaggg agcgagaccg ccatcaatat ctgataattc attttcagat
     7861 aaggataaaa aattgattgt caagaatgtc aaaatttgtc attgaacttt cctccttttt
     7921 tcttgttcac ttttatattc ggaaaagaaa aggaaaagtg agcatttttt aaattatttt
     7981 tagttaagtg agggcactct tgtctggggg caaagaaaat tcccatgtgc cagcttttgt
     8041 agtataatag taagcagaca aaaagatagg aatgtgttat gaaagtatta gcttttgata
     8101 cgtccagcaa ggctctttct ctggctattt tagaggacaa gcaggttctt gctgagacga
     8161 cgattaatat caagaaaaat cacagtatta ccctcatgcc agccattgat tttttgatgg
     8221 agagtttgga ctggacgccc aaggatttgg accgaatcgt ggtggcggaa gggccaggta
     8281 gctacacagg cttgcgaatc gcggtagcca ctgccaagac cttgactcat actctgaaca
     8341 ttgagttagt tggtatgtct agcctcttgg ctctggtgcc atatcaacaa gaaggcttgt
     8401 tcgttccttt gatggatgcg cgtcgcaaca atgtttatgc aggattttat gaaaatgcta
     8461 aacctgtcat gccagaagcg cacctatctt ttgaagaggt gctagaaaaa gtcaagggtg
     8521 ctagtcaggt aacctttgtc ggagaagttg ccccctttgt ggagcagatt caagaacact
     8581 tgccaaggac taattataaa gaaaccttgc ctaatgcagc caatcttgct cttttagctt
     8641 gggacaagga agcagaatcc ttgcatgatt ttgtgccaaa ttacctcaaa cgagtcgagg
     8701 ctgaggaaaa ctggctcaag aaccataccg agtctggtga gtcctacatt aaacgcctat
     8761 gatagaaatc aagcgaattc aacaacagcc tgacctagct caagccatct acgctgttat
     8821 ggcagctgtt tacctaatca gtccttggac tctggagcaa atccaagcag atctgtccca
     8881 agaccagact tggtatgcat tggcttatga tggggcagaa gtgattggat ttctagctgt
     8941 gcaggagaat ctttttgaag cagaagtcct gcaaatcgct gtcaaaggag cttatcaggg
     9001 tcagggaatt gcgtcagcct tgtttgctca attgccgaca gataaggaga ttttcctcga
     9061 agtcagaaag tcaaatcaac gagcgcaagc attttacaag aaagaaaaaa tggcggtcat
     9121 cgctgagcga aaggcctact accatgaccc agtcgaggac gccattatca tgaagagaga
     9181 aatagatgaa ggatagatat attttagcat ttgagacatc ctgtgatgag accagtgtcg
     9241 ccgtcttgaa aaacgacgat gagctcttgt ccaatgtcat tgctagtcaa attgagagtc
     9301 acaaacgttt tggtggcgta gtgcccgaag tagccagtcg tcaccatgtc gaggtcatta
     9361 cagcctgtat cgaggaggca ttggcagaag cagggattac cgaagaggac gtgacagctg
     9421 ttgcggttac ctacggacca ggcttggtcg gagccttgct agttggtttg tcagctgcca
     9481 aggcctttgc ttgggctcac ggacttccac tgattcctgt taatcacatg gctgggcacc
     9541 tcatggcagc tcagagtgtg gagcctttgg agtttccctt gctagccctc ttggtcagcg
     9601 gcggacacac agagttggtt tatgtttcgg aggcaggaga ttataagatt gttggggaaa
     9661 cccgtgatga tgcggttggt gaggcttatg ataaggtcgg ccgtgtcatg ggcttgacct
     9721 atcctgcagg tcgtgagatt gacgagctgg ctcatcaggg gcaggatatt tatgatttcc
     9781 cccgtgccat gattaaggaa gataatctgg agttctcctt ctcaggtttg aaatctgcct
     9841 ttatcaatct ttatcacaat gccgagcaaa agggagaaag cctgtctaca gaagatttgt
     9901 gtgcttcctt ccaagcagca gttatggaca ttctcatggc aaaaaccaag aaggctttgg
     9961 agaaatatcc tgttaaaacc ctagttgtgg caggtggtgt ggcagccaat aaaggtctca
    10021 gagaacgcct agcagccgaa atcacagatg tcaaggttat catcccccct ctgcgactct
    10081 gcggagacaa tgcaggtatg attgcctatg ccagcgtcag cgagtggaac aaagaaaact
    10141 tcgcaggctg ggacctcaat gccaaaccaa gtcttgcctt tgataccatg gaataaagag
    10201 tggctctttg tcaagtgtag tgggtaggcg aaaagctaca atctggagag tacgaaattc
    10261 gtactctctt ttttgatgtt caaagtcatc aaaatccgtt ttttaaaatt gttaaagttc
    10321 cggaaaccaa aggctttgcg cttgataacc ttaatcaaat tattggtcgc ttcaagttta
    10381 gcgttggaat aaggcagctt aagtgcgttg ataatcttat ctctatccct taaaaaagtc
    10441 caaaagaccg tttgaaaaag cggatgaacc gttggcagtt cttgctcaat caatccaaag
    10501 aaatggtcgg cattcttctc ttgaaaatga aagagcagga gttgatagag ttcgtagtga
    10561 acctgtaatc cctcagagta agaaagcagc ttatctcgta cttcccgatg ggttaagtgc
    10621 attcgaaacg tgggctgata gaatcgtttc tgacagagct tgaagctatc ctggtgtagt
    10681 aaatcagtcc agtggactga tttagcccga gcctagaaac gaaaaagcga gggttccaaa
    10741 agcgcttgag cgcccgatac tctaaggatt ttcggtcaaa ttggttcatg atttggattc
    10801 gtactcggtt catagctcgg ctcagatgtt ggacaatgtg gaagcggtca agaacaatct
    10861 tcgcctttgg aaagagttgc ttagcgagcc gataataagg gctgtacatg tccatggtga
    10921 tgacctcgac cagctcccga acctctctct gatagcgttg gaaatggttt cgaatcaccg
    10981 catgagttcg cccgtctaaa attgcgagga tggatttgga ctcaaaatct tgggcaatga
    11041 agctcatttt gctctttttg aagctatact catcccaact cataactttt ggcaacttgg
    11101 tccaatcggt ttcaaactta aattccctca gttttcggat gacggtggaa gttgagaccg
    11161 ccaatctgtg ggcaatctca gtcataaact gcttttcaag gaggagctga gcgatttttt
    11221 gtctcaccat gttggaaatc tggcaatttt tcttgacaat ggatgtttga gaaacgacca
    11281 ccttaaggca attcttgcac tgaaagcggc gctttttgag atgcagtacc gtgggtaaac
    11341 cctgacagtc gagaagcgga attttagagg cattctggaa gtcgtatttg atcatcttcc
    11401 cttgacaatg aggacaagga ggagcggggg aatccaactt tgcctgaacg actagatggg
    11461 tttggtattt cagaacagac aagattttga tatttttgtc ttccaatccg agcaaatctg
    11521 tggtattctt aagttgttcc atatgaaccc tttctaatga gttggttaga cgcttttcat
    11581 tataggtcat atggggcttt ttttctacaa gaaacgaccc tataattcct ggggtgggat
    11641 tacccactac agaaattata gagcccaaac attccaaagt cttgtctgac tctggaatgt
    11701 tttctgttca cagttgtttt gtaactgcct aataagtaac cgcgctataa cgaggtatct
    11761 accgagattg tcaattctcc agtatactgt tataaaaaac aaaactggag gattttttta
    11821 tgtcccccca tcgtcccatc ggctgttccg tagctgccca ataacggagt atagtcggct
    11881 gaaacaagaa taggacaaaa gtgcctcaag aaaagcatcg taatttgaca atattattct
    11941 gagatgtttt tgatgtaagc ccatattttc tcaatgggat tatactcggg tgaataggta
    12001 ggaagtggta acagtctatg ccctgctcct tacacatgtt cattctgtga aaccttgcat
    12061 ggtccataat gataagggat ggtgtatcta aagtaggtag taagaatttt tggaagcaag
    12121 cttcgaaaaa gtcactcgtc atcgtatctt tataggtcat cggagccata gtatattgaa
    12181 acaaaaaagg gcattagtac ttctataaca gtatcgcaat ctctggtgtg cgttgtctcg
    12241 atcttaattc aaataattat atcttcttcc agagagacta actgcctgct caaggctcga
    12301 tcatattcga gataaaaata ggtctcaacc cctgtctcat aaatataaat aggagtcagg
    12361 tagcttaagt gattcaattc tttaaggaac cgatttactt tttctgggtc ttgttcgcag
    12421 taggtacggc tcttttttag actatatccc atagccttta gagcgtaatg aatagttgtt
    12481 ggaggacagt tgaattcagc agctatttca gtcaaataag catcgggatg agtttcaata
    12541 tagatcttta atttatctct atcaactttt tcaattaata gtggaagttt tcttaaagtt
    12601 agtgtattga aacgttttta tacagtgcta aaatttgaag tgtagtgcag atatatttgt
    12661 aatagtatta tagcaattct ttggagaagg tcgagacaag agaaaatagg tatctttgag
    12721 atataagcat gatttactat aaaattattg agttattcat aaaaatttct ctatcaaata
    12781 tcataatgcg tcgtttaagg agatggttac aatgcaatat agttgtggaa aaataaatat
    12841 taatatccct gatggatatg gagacattaa ggatatagtg ttttcggctc atattatagt
    12901 taggtataat aatggacatt gtggaggtat agatccgcat ataattggac tttgtaaaaa
    12961 gcagatcaga aggatgtctc tatatcctat tttgataatc gtatctagag attcaaaggt
    13021 tattgatgat tataaaaatt tagatattgc ctatgttgat tgtactcaat gttcaaataa
    13081 ttttgaaact gccttacacg ttaaaaatat tttaaaatta ttaaaaatcc aacttataca
    13141 ctgtcatggc tactcaacta attatttttt atatatgtta aaaaaacttg acaagaatgg
    13201 atttggaaag gttaagacag tgataacatg ccatggatgg gttgaatata acttaaaaaa
    13261 gaaattcttg acttattttg atttttggac atattctatg ggagatgctt ttatttgtgt
    13321 atctgaaact atgaaaaaaa gattggagag tataataaaa aataagaaga tagttgcaat
    13381 aaataacgga attaatgtat caaatagcga tttagatgta gtaggtgttc aagactttaa
    13441 aaaagaattt tgtattccaa ataacaaaaa aatcatttgt tatgttggaa ggttggatcc
    13501 agaaaaaagg ccggatagat tccttgaatt tgcagaaaaa ttatttttag tcagagaaga
    13561 tgtgattttt attatggctg gaaatggtag tatgtgggct gctttgaaag aaaaaatttg
    13621 ccatttgaaa tgtagagata atttcaggtt acttggtgaa atctatccag ctactatagt
    13681 ttaccaaata tcggatttat tgtatattcc ttctgataca gaaggaatac ctatgtgtgt
    13741 tttagagtca atgtcacaag gaactccggt tttagctagt aatgttggcg ggttaagtga
    13801 aattattgaa catagggttg atggattttt atttgagaag gaagatgttg agggagtgtg
    13861 tgcttgtgct aattttttac tcaatgattc tgagtatttg aaatatatag gtgagaatag
    13921 taaatcaaaa ataagaaaac atttttctgt gcaaaaaatg tttgtagaaa ccatgagagt
    13981 atatgatgaa ttattagaga agagtagtca tggataggaa tatagatcaa gaattagtaa
    14041 gtattataat accaacacat aataggtatg aatctctgat tagagctgtg aaaagttgtt
    14101 tacatcaaag ttataaaaat atcgaagtta taattattga tgataattat agtaatgtaa
    14161 atttaagaaa taaaattatc catcaatttg gctataccaa tcatagaatt aagttaattt
    14221 taagtaatga agatttaggt gcaactaatg ccagaaacat aggtatcaaa aattctagag
    14281 gtaagtatat atcattttta gacgatgatg atgaatatat gccagatcga attttaaagt
    14341 tgatggcttg ttttaaaaag agtagaatga agaatttagc tttagtttat agttatggaa
    14401 taataattta tccaaatggt acacgagaag aggagaagac cgattttgtt ggaaatccct
    14461 tgtttgttca aatggttcac aatatagcag gtacgtcatt ttggttgtgt aaaaaagagg
    14521 tgctagaatt aattaatggt tttgagaaaa tagattcaca tcaggacggt gttgttttat
    14581 taaaactact tgctcaagga taccaaattg atatagtgcg agaattcttg gtgaattact
    14641 acgctcacag taaagaaaac ggtatcactg gagtgacaca aaaaacaatt aatgcagatg
    14701 aagaatatta taattactgt aggaaatatt ttaatttatt gagtttcaac gagagaatat
    14761 tggttacaaa gaaatattat tctttaaaca taaagcggtt actattaata ggagacaaat
    14821 gcaaggcttt aaaagtaatc aagaaggcaa gagaagaaaa aatttttaac gaatttcttt
    14881 ttttgaaata catgttatta tattattttg gttttttcta ttgtatatat gacaactatg
    14941 ttcaattaaa atttagaaag tgagaaacta ttgtgtatac tattataaaa tcaaatataa
    15001 aaaaatttag tttattaacg atatttattg ttgctggtca attattgcta atttatgcag
    15061 caactattaa tgctctggtg ttgaatgaat taattgcgat gaatttagag cggtttttga
    15121 aattgtcaat ctaccaaatg attgtctggt gtgggataat attccttgac tgggtagtga
    15181 aaaattatca ggttgaagtg atccaagagt ttaatctaga gattcgaaat agagttgcca
    15241 cagacatctc taactctacc tatcaagaat ttcatagtaa atcatcagga acatatcttt
    15301 cgtggctaaa taatgatgtt cagactttaa atgatcaggc ttttaaacaa ctttttttag
    15361 taataaaagg aatttctggt actatatttg cagttgtgac tcttaatcac tatcattggt
    15421 cattgactgt agccaccttg ttttcattaa tgattatgct acttgtacca aaaatctttg
    15481 catcgaaaat gcgagaagtt agtctaaatt taactagcca aaatgaagct tttttaaaat
    15541 ctagtgagac tatattgaat ggatttgatg tgttagcgtc cttgaatctt ttatatgtat
    15601 tgcctaagaa aattaaagaa gcaggaattt tattaaagat ggttatacaa agaaagacaa
    15661 ctgtagaaac gttagcaggc gctattagct tctttctcaa tatttttttt cagatatctc
    15721 tcgttttttt aacaggctat cttgcaataa aaggaatagt gaaaattggt actattgaag
    15781 caataggagc actaacaggt gttattttta cagcgctagg tgaattagga ggtcaattat
    15841 cctctattat tggtacgaag cctatttttt taaaattgta ttcaattaat ccaattgagt
    15901 caaataaaat gaatgatatc gaaccaaatg aggtgaatag agattttccg ttatatgaag
    15961 caaaaaatat ttgctataag tatggagata aagaaatatt aaaaaactta aatttttgtt
    16021 ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg aagcgggaaa tctacattat
    16081 taaaattatt gaatggcttt ttgagagatt atagtggaga attgcgattc tgcggggatg
    16141 atataaaaaa aacctcctat ttaaatatgg tttcgaatgt tctatatgta gatcaaaaag
    16201 cttatttgtt tgaaggtacg attagagata atattttatt ggaagaaaat tatactgatg
    16261 aagaaatact acagtcttta gaacaagttg gtttgagtgt aaaagatttt cctaataaca
    16321 ttttagatta ttatgttggt gatgatggga gattactgtc aggagggcag aaacaaaaaa
    16381 ttactttagc tagaggccta attagaaata agaaaatagt attaattgac gagggaactt
    16441 ctgctatcga taggagaact tcgttagcga ttgaacgtaa gatattagat agagaggatt
    16501 tgactgtcat tattgttacc catgctccgc atccggaact taaacaatat tttactaaga
    16561 tatatcaatt tccaaaggat tttatttaag aatatagggg agggaaacat gagattctat
    16621 tgtgaagctt atgaggtaat tactgaagag aaaaaagtat cattttttta tgtagatgag
    16681 aaacccttaa ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaaat
    16741 atcccaatct tatgaactgc accccaaaag ttagatttat tctgtctaac ttttggggtg
    16801 cagttcattt tgcatagtgt tggcattcat cccagatatc catataaaat gtctgagatt
    16861 gttgaaatgt ctaaaaaaat atcagatcta aacgataaaa aagaatttca caaaaagaac
    16921 tgtgagttga ggtttcaaga tagtgttctt gataacataa atagtgtccc gggtacaact
    16981 catttattta gttgtttaaa tattcaaaca ttagtaaaaa ttattttata tatttttcga
    17041 tacaacagtt gtatgaaaat atttaatttt agagataaag agcttatctt ttttaataag
    17101 attgtaaatg ggctgataca aaatattgag gagaatttag aggatgatat tgaaaggata
    17161 ttgaaatatt tatatatatg tttatttaac gaaatattca ttattaagaa taaggtgaat
    17221 ttttttgatg atgtggaatt taatcagaca cttagtgagt ttttagataa attgtagagg
    17281 gaatggttat gagtaacaat actaagtata tctttttatc tccacattta gatgacgcaa
    17341 ttttttcctg tggtgattat atttcaaaat taacttcaga aggagaaatt gtacttgtta
    17401 ttactatatt ttctggttac cctttgagcc aacagctaca gccctctgct aagcaatttc
    17461 ataagttgtg taaccttggg aaatatccga ttgaagaaag gaagaaagaa gacaggttag
    17521 cttgtgaacg tctacaatgt gattttagac acttatcgta ctatgaatgt ctctatagga
    17581 aagatagaaa tggcaatttt ctataccgtc atatctatag tgaattaaaa aatgaggaca
    17641 cattaaagaa tgatatcata aaagagctgt taatgcattt agacgacaaa tgtgtcgtat
    17701 attgtccgct ttcacttggt gaccatgttg atcatgtttt tgtgaatagt attggaaggg
    17761 cgcttgaatt tatgcgttat aaagtaatat attatgagga cttcccatat gtaagtgata
    17821 gtagtatggt tagttatatg ggaaaaacta aagaattaaa aatgtatcaa gaggaacttg
    17881 atgaaaaaat tatattgata gaatatcatc aatattgtgc tataaatctc agattttgat
    17941 aatctggaaa tcagttgaaa aacttttaaa caatattaaa gagttgtatt taaggaatgg
    18001 ggcagcttat tctattagat tttggattaa gaaataagga agtagtttta tgaatatagc
    18061 agtaattggt ttggggcatg ttgggctggc ctacgcgtta ctatttgcat ctaaatataa
    18121 agttgttgca tatgatatag attctgtaaa aataaataat ttaaaaaagg gcattcttcc
    18181 atctaaaaat gaagagctta tgaagttttt ttgcgagaat aacttaaata ttactttttt
    18241 tgatacattt tctgaaatta aaaataatat tgattattat attattgcgc ttccgacaga
    18301 ttatgatgag aaaattggta gttttaatac atatgaaatc gaacaaacgg tatcgaagat
    18361 tctgagggta aaacctaatg gaaagattat tttaaagtca acagttccga tcggcttttc
    18421 aaacaaatta aaaaggttgt ttgatacaaa aaatatcatt tttgtccctg aatttttgag
    18481 agaaggttgt tctatatatg ataatttata tccaagtcgc atagttgttg gagatgagac
    18541 agttgaagga agaaaaattg cagagttgtt cctttcgatt agtactcata gtactgccaa
    18601 tattaaaaat gttatgttag tttctcctac tgaagcagaa gcaattaagc ttttttctaa
    18661 cacattctta gctctccgtg ttgctttttt taatgaacta gattcttttg ctgagaggag
    18721 aagtttaaat gctgaagttg taataaaagg tgtttgttta gatccaagaa ttggaaattt
    18781 ttataataat ccttcttttg gatttggagg atattgtctt cccaaagata ctaaacaatt
    18841 aaaaaaagaa tttatagaaa taaatgcccc agtgatagaa gcgattgata tttcaaacac
    18901 aaatagaaaa cagttcatag ttaaacaaat attggaacga aagccaaaga tagtaggaat
    18961 atataaattg gggatgaaat ataattcaga taattacaaa gagtcagcta ttttaagtat
    19021 aattaatgaa ctattgattg tcggtataaa aattttagta tatgaaccaa atttaaacgt
    19081 tagtatagat aacgtaattt ttgaaaagaa ttttgaacta tttacaaaac aaagcgatct
    19141 aattgttgca aatagatggg ataggggcct tgaagcttat aaagataaag tttacacaag
    19201 ggggatctgg ataagagatt aactattgat attaaaaagg caataattta taaaatttgt
    19261 acaaaaaaat gttaaatttt cacattttca tagtatactg tttaatagaa agtaggttct
    19321 ttgtaaccgc tccattataa aatcctttca ctcttccggt atactattag gaaaaacata
    19381 actggaggat attttgagct cacacctcat cgttccagtg gctgttcccc aagctcgtgt
    19441 actgcccaaa aaagttagac attctattta gaacgaggat tgagttctgt attgtacaag
    19501 gctcggtcct tttagagtca gcttaaggct ggctttttta atcaccaaag tgtcagaatg
    19561 ttttgacaaa tgaacacaaa taatgatata atatgcaaaa gctaggaggt ggtaggatga
    19621 ttgaaaaaat ggaactgggg gaattttaca aggaattgcg tttggcgaga aagctcaagc
    19681 agtcagatgt ggcttgtgct ggactaacag cttctcagct atccaagttc gaactagggc
    19741 agtctatgct gtctgcggat aagctcatac tagccatcca agggatcaat gtgacctttg
    19801 atgagtttgg gcacaagctc aacaactatc aagaatctcc acatatgcag attggtagaa
    19861 aggttgtgga tcgctttgct catcaagata tagctggctt agagcaactg ttggaggaag
    19921 tcgagcaagg acagatggcg gagacctatc gtcgtttgaa tgctattgtg attaaaaatg
    19981 cactccattc cttagataaa agctatccgc tagcagagga ggatagcgag tttttgacta
    20041 cctacctcta tgctattgag tcttggacct ggtttgaact ctatcttttt tgcaatacca
    20101 tgcccttctt gagcaatcaa gatctgatct ttttatcaac ctctttgctt gaaaaatcca
    20161 aggaatttaa agagttggta cataatagac tgtatatgaa aagtggcttt ctgaatatta
    20221 tatcagagct catggagcgc aagcttttct cctatatccc aatctttgaa gcagagctgg
    20281 agagcatgtt gcgtccgtac gatgtttttg aaaaagtatt gtggcaattt ttaaagaaaa
    20341 tgagtatttt ccttcaaacc aaaggaaaca atcaaaaaga gattgaaaat tttatccaat
    20401 ctctgcaagt attagaaaat ccacaattaa catccctttt tgaattgcgt tttcagcaat
    20461 ataaagaact tatagattag ttaaaaatgg aatggcaata acccactccg aaataagtag
    20521 gagtatcagt tggatttttc ttttcttcat ctattatatt cctccttgtt agtaataact
    20581 ttattatacc agggaaataa tcaaatctat caaaatcgca aataagaaat ttctataaga
    20641 aaaaatatca aatatgcgat tttttaaaat aagccaattt tcgtgttata ctgtacttgt
    20701 aaagcacttg aagcaaatcc taggtcgcag aagtggttta caaatgaaga taattgaagg
    20761 agtgtaaaag atgttaaatt tacaatttgc agaaacaatg gaattgacag aagctgagtt
    20821 ggagacagtt tatggagggg aatttgggaa taatgctgtt atcccagccg gtgcttgggg
    20881 aggtttagga acgtcttggt caatcactaa tttctggaag aaatatttta accatgattc
    20941 ttccactgtt aatcgtcgcc attattgata ttcagagtcc ttgccttttt cttgggtagg
    21001 gactgtcttt atttcatagt ataggagaaa atagaatgaa aaagataatc tcacaccgct
    21061 actttattat agtttttcta ctagttattg ctgaccagaa gttcagtgtt ttagttttac
    21121 gcagcgacct tgttgctggg ctatctgact ttgcctatta tctgtcggat atgatgttga
    21181 attttcttgt ggttttattt gctcttattg ctatgatttg gtcggggaaa tggcagaaaa
    21241 tcaatagtag aaagtttaaa ggatcctatc ttttctattc cttcctagct ctgcttgctt
    21301 ttgttgcttg gaattttgtc accttttttc ttttcccacc tactcgaaat gaaatttctt
    21361 atcaacatgc tgctcctact tttacaggag ctacggcatt tttgatgtat tttttttatc
    21421 ctgtgattgc aggtcccatt tttgaagaca tgatttatcg tggattagtg atgactgctc
    21481 tggaaaaagg aaagaaatgg gggctagatg tacttggttc cgctgtttta tttggggtct
    21541 cgcacattag taatcacggt tgggtcttga cagactttgt cttctatatg ggtggaggtc
    21601 ttatatttgc agtcttattt agaatgacaa agtcaattta ttggcctatt ggactgcata
    21661 tagtctacaa cggcattggt cagcttttga tgttactgta attttggttg ttagtagtat
    21721 cgcggtctat ttctggggaa agattcccat ttgaacttaa gaaggagttg tgatgaaagt
    21781 atttcttcaa aatagagatt ttaggcaatt aactatcaac cagtggattt caacgcttgg
    21841 ggatacgatt ttttatctgg cctttctgaa ttatgtggca gatgcgtctt ttgcaccttt
    21901 ggcgatttta ctcattacga tttcagaaac ccttccccaa attttacaaa tctttctggg
    21961 agttttggca gattttcaac atcatcgtgt cttgaaatac acagtcatta gttttacaaa
    22021 atttttgctt tactctatag tgtccctatc gctttcaggg cagtcttttt ccttgttgct
    22081 agtaaccttt atttgtctgc ttaacctcgt gtctgataca ttgagtgctt tttcaggcgc
    22141 catgctcact ccgattttca ttagaattat tgggcaagac catctggcag aagctattgg
    22201 atttaaacag tcaactgtta gtttagtgaa aacaatcagt aatatcctag gaggagtctt
    22261 actaggcatt ctatccatcc agtttatttc cttactgaac gctcttacct ttttaatcgc
    22321 atttttaggt atcctcttca taaaaactga cctcttgaaa gtagaaaaaa cgattagcta
    22381 tcaagaagga ctctctgtaa aatccttttg ccagcatttg ctccaatcat cgaaattgat
    22441 atggaatatg aataaggtgc tcttggtttt gtttattatc tctactagtc aagcagtgat
    22501 aaatgttacg gttcctgtct ctactctatt tttgaggaat caaccctttt tgaatttaca
    22561 aacaggtcaa tctcttgcct tgctatccac ttttgaactg tcagccctga ttgtcggaag
    22621 ccttgtaagt ggctatctgc aacataccat ttccataaaa acagctctct atgcctcact
    22681 tgtcatccag ttgcttcttc tagtaggatt tgccacagtt cgttttgact ggattctcat
    22741 ctttagtacc ttggatgcct ttttcgcagg tgttctctct cctagattgc aagaactcgt
    22801 ttttaaacaa atacctgagg agtcaatggg agcagttcaa tcttctatca gtgccattac
    22861 ggttgtttta cctagcttat ttacaatagc tttggtaacc attgctacta gctttggaac
    22921 tctggcagtt agctttgttt tattgctatt tcttctagtt gcctttgtca tgcttctgaa
    22981 tattcgtgaa agtatttagt ggagaatttc tataatatat gtttgagact ggattgccag
    23041 tctttttatg atggtcaaaa tcaacagact tttttctctt ttctgaatgt gttata
//
LOCUS       DAVEHY010000033        22918 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVEHY010000033 DAVEHY010000000
VERSION     DAVEHY010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.033"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(331..1179)
                     /gene="dprA"
                     /locus_tag="VUZ44_001606"
     CDS             complement(331..1179)
                     /gene="dprA"
                     /locus_tag="VUZ44_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU0320481.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1275..1964)
                     /locus_tag="VUZ44_001607"
     CDS             complement(1275..1964)
                     /locus_tag="VUZ44_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU0320482.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1976..2854)
                     /locus_tag="VUZ44_001608"
     CDS             complement(1976..2854)
                     /locus_tag="VUZ44_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU0320483.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2844..3713)
                     /gene="licA"
                     /locus_tag="VUZ44_001609"
     CDS             complement(2844..3713)
                     /gene="licA"
                     /locus_tag="VUZ44_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU0320484.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3730..4752)
                     /locus_tag="VUZ44_001610"
     CDS             complement(3730..4752)
                     /locus_tag="VUZ44_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU0320485.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4757..5464)
                     /locus_tag="VUZ44_001611"
     CDS             complement(4757..5464)
                     /locus_tag="VUZ44_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU0320486.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5800..7287
                     /gene="tacF"
                     /locus_tag="VUZ44_001612"
     CDS             5800..7287
                     /gene="tacF"
                     /locus_tag="VUZ44_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU0320487.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7297..8100
                     /locus_tag="VUZ44_001613"
     CDS             7297..8100
                     /locus_tag="VUZ44_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU0320488.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8102..8911
                     /locus_tag="VUZ44_001614"
     CDS             8102..8911
                     /locus_tag="VUZ44_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU0320489.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9186..12362)
                     /gene="carB"
                     /locus_tag="VUZ44_001615"
     CDS             complement(9186..12362)
                     /gene="carB"
                     /locus_tag="VUZ44_001615"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU0320490.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTRLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAIAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12674..13753)
                     /gene="carA"
                     /locus_tag="VUZ44_001616"
     CDS             complement(12674..13753)
                     /gene="carA"
                     /locus_tag="VUZ44_001616"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU0320491.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13803..14726)
                     /locus_tag="VUZ44_001617"
     CDS             complement(13803..14726)
                     /locus_tag="VUZ44_001617"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU0320492.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14745..15266)
                     /gene="pyrR"
                     /locus_tag="VUZ44_001618"
     CDS             complement(14745..15266)
                     /gene="pyrR"
                     /locus_tag="VUZ44_001618"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU0320493.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15477..16106)
                     /gene="nth"
                     /locus_tag="VUZ44_001619"
     CDS             complement(15477..16106)
                     /gene="nth"
                     /locus_tag="VUZ44_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU0320494.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16106..16648)
                     /locus_tag="VUZ44_001620"
     CDS             complement(16106..16648)
                     /locus_tag="VUZ44_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU0320495.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16818..17135
                     /locus_tag="VUZ44_001621"
     CDS             16818..17135
                     /locus_tag="VUZ44_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU0320496.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYDHVKHVLSLYGPV
                     FEF"
     gene            17374..18933
                     /locus_tag="VUZ44_001622"
     CDS             17374..18933
                     /locus_tag="VUZ44_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU0320497.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRLLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(18977..19876)
                     /gene="htpX"
                     /locus_tag="VUZ44_001623"
     CDS             complement(18977..19876)
                     /gene="htpX"
                     /locus_tag="VUZ44_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU0320498.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19878..20438)
                     /locus_tag="VUZ44_001624"
     CDS             complement(19878..20438)
                     /locus_tag="VUZ44_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU0320499.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20532..21245
                     /gene="rsmG"
                     /locus_tag="VUZ44_001625"
     CDS             20532..21245
                     /gene="rsmG"
                     /locus_tag="VUZ44_001625"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU0320500.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            21499..22782
                     /locus_tag="VUZ44_001626"
     CDS             21499..22782
                     /locus_tag="VUZ44_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU0320501.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
BASE COUNT         6892 a         4859 c         4253 g         6914 t
ORIGIN      
        1 tcactatact ttcccttata ctcaatgaaa atcaaagcgc aaactaggaa gctagccaca
       61 ggttgctcaa agcactgctt tgaggttgta gataagactg acgaagtcag ctcaaaatac
      121 tgttttgagg ttgcagatgg aagctgacgt agtttgaaga gattttcgaa gagtattata
      181 tgagaaaaat cctctactct actaatccac ttagaaaaaa cgcatattat caagtgttaa
      241 aaacttgcta atatgcgttt tattatggaa atgttgggtt cattttctct taaaattgat
      301 tttttcttag aattttagct taggtcattt ttaaaattca aattccgcaa gaacatcttg
      361 cccactggtg accaattttg ctccttcttg aatcaaatga tggcaaccgt ctgatagtcc
      421 atctaaaatg ctaccaggaa tagcaaagac atcgcgtcct tcttccattg ctcgctcaca
      481 cgtaatgaga ctacctgaac gcatcttagc ctctgctaca atcacaccac gacaaagtcc
      541 agcaatgatg cgattacggg caggaaaatg aaatttcaga ggttgttcgc caggtccata
      601 ttcacttaga accagatggt cattgccgat gtagtcttgc aagcgtttat tggctttagg
      661 ataaaacaca tccagtcctg ttccaatcac tgcaatggtt tttccgccat tctgaagagc
      721 tgccatatga gctgctgtgt caatgccctt ggccagacca ctgacaataa ccagttcatt
      781 ttccaagcct tgaatgactt tttcaactga cttagctccc tgtttgctac aagcacgact
      841 gcccacgacc gctaccttcg ggaatttcag gaggtcaaga tttcccttgt aaaataaaag
      901 tacaggcgca tcatatattt cactcaaatc ccaaggataa cagtcatcta aaatagagaa
      961 agatggaaat ttttgaaact ctttcgacaa atgcgcatcg tctatctgaa aataacgttc
     1021 cataaaaacg gctggattac ggcaacctga tatatctgca atatcaccca acaaaagctc
     1081 ctgatcaaca ttttcaccgt attctagcac tttcaaaatc tgttgattgg tcaaacctga
     1141 tttttttaac ttatagattt catagtttgt gattttcata aataactcca tttctttttc
     1201 tactcatcta tctattcgta aaagttcgta aaaaatcaaa aaacatccga ctattttgtc
     1261 agatgttgga atctttaatt ttcgttttta agaatttctt ctaatttacg atagtcttgg
     1321 acactatcga tctcataaat gctattgcct tctaattctt caacatagac atctagctct
     1381 ttgatattat ccttaaccat attgtcccaa tagagatcaa caaattcgcc acttgcataa
     1441 gccttatcga taaagctgac aatcttttct gcagttggag catcccagaa ggatacacca
     1501 ctaaggatgc gacctgcctt gctatcaaca ataatgtctt gaaccttgta gtcatctcca
     1561 tagaccaaga accattcgtt ggtacaatct tcacgataaa cactaaaata agtcgaacga
     1621 gtcaaatcat tgcggaacat atttttaaag agataattgt cagcatcaat aacatagctg
     1681 ttggccaatt cttcttttac aagatagaga gagtaaaagt tattgtagtc agcgtattta
     1741 tcattgaaaa cgaggcgaac accgtatttt tcttttaagt aatcgaattg ttctttaaga
     1801 taaccaacaa tgatgatgat gtcattgatt cctttttctt tgagaaactc aatttggtac
     1861 tcaattaagg gtttttgatt aacctgaacc aaggctttag gggtattttc agtcatagga
     1921 cgcaagcgag ttcccaatcc cgctgctaag atgatggctt tcacacgaat ctcctttatt
     1981 ctttaataat aatataaact ccagcaatga cgacaagtga cgtcataatg gtcagcatat
     2041 ctagtggtgc acctaagaaa acaactgcaa acaagactgt ccatactaca tagctcacat
     2101 tcaagcctgt agccttggct ggttgcaagc gattgatagc gatataataa gccaagtagg
     2161 aaatcatatc aaaggctgca aaaacaatca tgagacctag caattgtcca ttggctactg
     2221 cagtaaatga ctgatgagag aagagcacaa tcacaagata ggacaagaac gaagtcactt
     2281 gacggattaa gagggcttcg atttcactca gttcactttc catagcaaag gagctaagaa
     2341 cactctcact tccccatgca atagcacaaa ccaaagcaca gagaatccca atgtagaagg
     2401 aattaacctg ttcaacttta taggtctggg caataatccc tccaataatc aagacaattc
     2461 caaatacagt atttttcgaa atcttgtgct tcaaaaagaa gaaagccaat agaactgaaa
     2521 tcgcagggta aatagccgat acagatgaag ctaaagaact tccgatatac ttaactgcat
     2581 aaagattggc ctgcataccg atagggcctg ctagcaaggc tccgatgata acactgacat
     2641 tgcgaatatt taagaaaatt gagaggcgaa ctttcccttc ttttaccaag agaaaagcta
     2701 gtaagataaa gatgctcaaa aaatcatgag ctgcagccac cacaaagggt gacaaatctg
     2761 taaaaatcga aaagatataa gcactaaccg ttagacccaa gccccagaaa atacctgaga
     2821 gaaggccaaa aggaactccg tttttacttt tcatctgaac ctccataaga agccaaacct
     2881 ttaacagctc tttggtaacg attcacacca tagtcaccaa aatcttcacc ttgctcttcc
     2941 ttatagacag tccatagact ccaaatagta tcttgtaaaa ttttataaat agcaatcttt
     3001 tcatgagaaa ccggtgtttg gtcactctca tagtgagata agaaagtttc ttcctcttgg
     3061 gaagtgaatt cagactctaa aaagagggca gccaaatccc acattggatc attcattgat
     3121 gaatattccc agtcaatcaa ataaagtcgt ccttgaggtg attcgataaa gttttcaggc
     3181 accaaatcga tatgacaaga ttttctgtca acacctaagt cagccagtct tttctctaag
     3241 gagaagactg catttctaac agattcatag ttggcataag gaatttgttc ttcaatcaag
     3301 gattcgtatt ttttgatttc ttcaaaagga gcaaattctc ctcttaattc cttagcagac
     3361 gtatgaatag tttgtaatat tggagcaatt ttgtcgaact tggtcttgat tgacgttgaa
     3421 tcaagcgtaa tcgcagattc gatatactca tttactttga taccagcttc aatatcaaaa
     3481 agataatttt ttacatctaa gcctaaatcc tttagtagtt caagattgta cttttcatct
     3541 tgtcgattga taagcttttc tgtcccttta ccaaagaatt taacaatgta ttgcttattt
     3601 gttgttttgg ccaaatagtt ttgattggtc attccaccca gttgttcaac actgaggact
     3661 tcctcttctt gactaagtaa ggaagaaatt ttttctttaa tgattttctc cacaattaac
     3721 ctccagtact tatacttccc acttaaacac tgttttaaag gctgtgttta aatcggttgc
     3781 aaagacacga tgaatatctt taatttctct tacaggttct tctagataaa ggatattttt
     3841 aagacgattg gcaaatttct tgacttccat catttggata gcatttttaa aatcaatgcg
     3901 accagaacga gatgacccaa ccaaaatcaa gcccttttct aaggcatcgc gagtattgag
     3961 attgacttta tattcgctaa ctcccatcat gagaatcgtt ccctgaggac gaatgtagcg
     4021 aatcaagtca ttaatagctg gtccagtacc atcaccacca caacattcaa aagcatggtc
     4081 aaaggccaac tcttcaggaa tattatccgt aatatagcat tctttggcaa atgagaagag
     4141 ttccaacttt tcccaatgac gaccaataac cacaatctct gattctggca aagtatagtt
     4201 gataatattg gcaaccacaa aagctaaact tccatctcca ataacggcga tccgctcccg
     4261 cttgctatga gcaagagtca atagacgatt catagcgtgc atgcccacac tgacaaactc
     4321 tgtaatggct gcaaccgtat cttcaatagc atcataagcc accacacgat ctttagggag
     4381 agaaacaaac tctctcataa agccatcaaa tccactagac aagaaatggg tccctgtcat
     4441 gtagttttca tagaattctt catcactctg cataggagac tgattgggaa tcatgacaac
     4501 tttttgacca acctcgtagg ttccggtcgg gtcagaaatg acggttccac atgactcgtg
     4561 aatcattgcc attggaagct ttttattcaa aatcttggga tcacgttttc cctggtagta
     4621 acgctgatcc gcatgacaga cagccatgta gttgggacgg ataaggatat gattctcttg
     4681 gtcaatagcc tcttcctgat atttgacatt gataaactta ggcttagtta gttgataaat
     4741 ttgattaatc attttactag tctttctcaa tcatactttt tgcaatcttc aaatctgtta
     4801 cggttgtaat cttcagattt gagtattcac ctttggccaa ggccacatct tttcctttga
     4861 tcacaaagat tttacatgca tctgtcaaga tttccttctc ttcatcagaa agagatccat
     4921 aaaggtccat gaagtccttg caacggaatg tttgaggtgt ttgtccttga taaaggtgag
     4981 cacgatttgg aatatctgta ataaattgac cattggtact ttcaacgata gtatcaaccg
     5041 cttctaccac tgtgtccact gcgtcatgat tttgggcaag ttggatattg tcctgaatca
     5101 tgcgaagtgt aataaatgga cgaacagaat cgtgggtaac aacgatatcc tctggagtaa
     5161 gtggacgata agcatcaatg gcttcaatga ttttcttaat acttgtattg cggtcagcac
     5221 caccctttgt aatgatgata cgttccttat aaagaggaag atatttatct acaagatctt
     5281 ctgcatgaga aacccagtct ccatgaacac caactacaat tttttcaata cttggctcca
     5341 agacaaattt ttcaattgta tgaatcaaaa taggtcgatc acctagctct aaaaattgtt
     5401 ttggcaagtt actgattccc atgcgtgtgc cagttccacc ggcaagaatt cctgcataaa
     5461 tcatctattt tctcctttgt cttactaaaa aaacttattc tctctattat accacaatct
     5521 agtcctatca taaaaaaaat actggtcctc cccttctaga ataggagaat tatgcagttc
     5581 tattattcaa agaaactagt ccatttctag taatgactag gaattctgta gcaattacta
     5641 ataaatggct gcgaaatttt agagttcttc agaataatat actttcctta aagaaaactt
     5701 aaaacttaag atttgaaact tcaaagtgat tacttgactt actgcccttc atttcttatt
     5761 agctaacttt atgatataat gaaaaacgag gtaaattgaa tgaaaagtat aaaattaaat
     5821 gctctatctt acatgggaat tcgtgtcttg aatattattt ttcccatcct aactggaacc
     5881 tatgtcgcgc gtgtcttgga ccgaactgac tatggttact tcaactcagt cgacactatt
     5941 ttgtcatttt tcttgccctt tgcaacttat ggtgtctata actacggttt aagggctatc
     6001 agtaatgtca aggataacaa aaaagatctt aacaggacct tttctagtct tttttatttg
     6061 tgcatcgctt gtacgatttt gaccactgct gtctatatcc tagcctatcc tctcttcttt
     6121 actgataatc caatcgtcaa aaaggtctac cttgttatgg ggattcaact cattgcccag
     6181 attttttcaa tcgaatgggt caatgaagct ctggaaaatt acagttttct cttttacaaa
     6241 actgccttca tccgtatcct gatgctggtc tctattttct tatttgttaa aaatgaacac
     6301 gatattgttg tctatacact tgtgatgagt ttatcgacgc tgattaacta cctgattagt
     6361 tatttttgga ttaaaagaga catcaaactt gttaaaattc acctaagtga ttttaaacca
     6421 ctctttctcc ctctgacagc catgttagtc tttgccaatg ccaatatgct cttcactttt
     6481 ttagatcgcc tcttcctcgt taaaacaggg attgatgtca acgttagtta ctataccata
     6541 gctcagcgaa ttgtgaccgt tatagctggg gttgtaacag gtgcaattgg agtgagtgtg
     6601 cctcgtctca gttactatct ggggaaagga gacaaagaag cctatgtttc tctggttaat
     6661 agaggtagtc gaatctttaa cttctttatc attccactga gttttggact catggtttta
     6721 ggaccaaatg ccatcctact ttacggtagt gaaaaatata tcggaggcgg catcttgacc
     6781 tctctcttcg cttttcgtac gattatcctg gccttagata ccattcttgg ttcccaaatt
     6841 ctctttacca atggctatga aaaacgtatc acagtctata cagtctttgc tgggctactc
     6901 aatttgggct tgaatagtct cctctttttc aaccatatcg tggctcctga atactactta
     6961 ctgacaacta tgttatcaga gacttctcta cttgttttct atatcatttt catccataga
     7021 aaacaactca tccacttggg acatatcttt agctatactg ttcgatactc tctcttttca
     7081 ctttcctttg tagcaattta tttcctgatt aatttcgtgt atcctgtgga tatggtcatt
     7141 aatttgccat ttttgattaa tactggtttg attgtcttgc tatcagctat ctcttatatt
     7201 agtctacttg tcttcacaaa agatagcatt ttctatgaat ttttaaacca tgtcctagcc
     7261 ttaaaaaata aatttaaaaa atcataggag tttaaaatga aacaactaac cgttgaagat
     7321 gccaaacaaa ttgaattaga aattttggat tatattgata ctctctgtaa aaagcacaat
     7381 atcaactata ttattaacta cggtactctg attggggcgg ttcgacatga gggctttatc
     7441 ccttgggacg acgatattga tttatccatg cctagagaag actaccaacg atttattaac
     7501 atttttcaaa aggaaaaaag caagtataag ctcctatcct tagaaactga taagaactac
     7561 tttaacaact ttatcaagat aaccgacagt acgactaaaa ttattgatac tcgaaataca
     7621 aaaacctatg agtctggtat ctttatcgat attttcccta tagatcgctt tgatgatcct
     7681 aaggtcattg atacttgtta taaactggaa agcttcaaac tgctgtcttt cagtaaacat
     7741 aaaaatattg tctataagga tagcctttta aaagattgga tacgaacagc cttttggttg
     7801 ctccttcgac cggtttctcc tcgttatttt gcaaataaaa tcgagaaaga aattcaaaaa
     7861 tatagtcgtg aaaatgggca gtatatggct tttattcctt caaaatttaa ggaaaaggaa
     7921 gtcttcccaa gtggtacctt tgataaaaca atcgatttac cctttgagaa tttaagcctt
     7981 cctgcacctg aaaaatttga tactattttg acacaatttt atggagatta tatgacccta
     8041 ccaccagaag aaaaacgctt ctacagtcat gaatttcacg cttataaatt ggaggattag
     8101 gatgcaatat ttagaaaaaa aagaaattaa agaaattcaa ctagccctgc tggactatat
     8161 tgatgagact tgtaagaaac atgatattcc ttattttctc agttatggaa ccatgcttgg
     8221 agccatccgc cacaaaggta tgattccttg ggatgatgat attgatattt ccctttatcg
     8281 tgaggattat gagcgtttac tgaagattat tgaagaagaa aatcaccctc gctacaaggt
     8341 tctttcctac gatacatctt cttggtactt ccataatttc gcatcgattt tggacacttc
     8401 tactgttata gaagaccatg ttaagtacaa gcgtcatgat accagccttt tcatcgatgt
     8461 cttcccaatt gatcgattta cagacttgag cattgtcgac aagagctata agtatgtggc
     8521 tcttcgtcaa ctagcttata tcaaaaaatc acgagcagtt cacggtgata gcaaactaaa
     8581 agattttctt agattatgta gctggtacgc tctccgattt gtcaatcctc gctactttta
     8641 caagaaaatt gatcaactag tcaaaaatgc tgtaaccaac actcctcaat atgaaggagg
     8701 agttgggatc ggtaaggaag ggatgaaaga aatcttccca gttgatacct ttaaagaact
     8761 gattttaact gagtttgagg gccgtatgtt gcctgttccc aaaaaatatg accaattttt
     8821 aacccagatg tatggcgatt atatgacacc accatcaaaa gaaatgcaag agtggtatag
     8881 tcatagcatt aaagcttatc gcaaaaactg attgaggggt attatacaaa ctactaagat
     8941 agaggttatt caaaaacata attttagtag aaaatgaaat acatattccc acaataaaac
     9001 gcatcatatc aaggtttttg aaaaaccttg atatgatgcg ttttataatt ttaaagactt
     9061 ttttctatag tagattgaaa taagatgcga acgaatcaat tagaaaattc aaattaattt
     9121 ctagaaatat tttagtatcc ctgtgtactg ttctaaattc agtctgctat atcttatttt
     9181 tctatttaaa tcgcttctgt aacaaagcta cgactttcaa gtaccttaag catggcatta
     9241 gctgtatcta gcgctgtgaa gaggggcacc ccgtgttcaa tggctgaacg acgaatttgc
     9301 tcaccatctt cgtcagcagt tcgttttgtt cctactgtgt taatgatagc ttgaattctt
     9361 cctttgcgta caaaacttgg gatatcctta tcgtcatcac caatcttacc aacaggttgg
     9421 gcttgcaagc catggctagc aaagaaggct gctgtccctt ctgtcgcaag gattccataa
     9481 ccaatgtttt ggaaacgacg agccaagttc aaggcttctt ctttggcatc atcagcgatg
     9541 gtaaagacga cattaccaaa agttggcaag tgtagataag aagcttcaaa ggctttatag
     9601 agagcttttt ccaaagtagc atcagaaccc ataacttcac ctgttgactt catttcagga
     9661 ccgagcaagc tgtctacctt agctagtttg gtaaaggaga agacaggtgc cttgatatga
     9721 acacgggtgc tttcagggta aagtccattt tggtagccaa gttctgataa actttgacca
     9781 agaatgagct tggtcgctac ttgagccata ggaatattgg ttaccttaga taggaatgga
     9841 acagtacggc tggcacgtgg attgacctca ataacgtaga ctttttcatc cttgataaca
     9901 aactggatgt tcatcattcc aaggcagtga agaccgattg ctaagcgttt ggtgtagtct
     9961 gcgatggtct cctgaacctt ttgcgacaag gtttgtggtg ggtaaacagc cattgagtca
    10021 cctgagtgga caccagcacg ttcgatatgc tccatgatac caggaatgag tacatcttta
    10081 ccatctgaaa tggcatcaac ttcgcactct tgcccaacga tataagagtc gacaagaact
    10141 gggtgatctg gactagcctt aacagcagtt cgcatgtaag aacgaaggtc ttcttcgttt
    10201 tcaacgattt ccatggcacg tccaccaagt acataagatg ggcggacaag aactgggaag
    10261 ccaatcttac gagctgcaag agctgcttct tcttcattgg tagccgtttg tcctggtggc
    10321 tgtggaatat ccaattcttt gagagcttgc tcgaagaggt cacggtcttc ggcacggtct
    10381 aggtcagcaa cctgtgtacc aaggatggtc acacctgctt ttgccaatgg ctccgcaagg
    10441 ttgatggctg tttgaccacc gaactgaacg ataactccct ttggttgttc caagtcaatg
    10501 acgttcataa catcttcgaa tgtcaatggc tcaaagtaaa gcttatctga tacagagaag
    10561 tctgttgaaa cggtctctgg gtttgagttc atgatgatag cttcataacc agctgcctgg
    10621 atagccttaa cagagtgaac ggttgcgtag tcaaactcaa ccccttgacc gatacggatt
    10681 ggacctgaac ctaggacaag tacagattct ttatcagatc tgatagattc attttcccaa
    10741 ccataggttg aatagaaata tggcgtttcg gagtcgaact ctgccgcaca agtgtctacc
    10801 atcttataaa ctggaacaat cttgttttcc aagcgaagtt ggcgaacttt atcatcagtc
    10861 gttccccaga gttcagcaat cttacggtct gaaaaaccat taagtttggc tgttttcaaa
    10921 acttctagat cttgtggatg agcacccaat tcttgctcaa tttcaaagat atgcaagagt
    10981 ttatcaagat agaagatatc aatttttgta agctctgcaa tttcttcagg tgtgtagcca
    11041 cgacgaattg cttctgatac gtagaagaga cggtcatctt gggctttgac aaccttttca
    11101 atcaaggcat catcagaaac tgctgcaagt tcaggtattt cattgtggtg caccccaatt
    11161 tcaagggagc ggcaggcctt gagaagagat tcctcgatgt tacgaccgat tgccatgact
    11221 tctccagtcg ccttcatttg tgtaccgaga cggcgttcac ccttttcaaa cttgtcaaat
    11281 gggaaacgtg gaatcttagc aactacgtag tcaagggctg gttcaaacat ggcataggtt
    11341 gaacctgtaa ctgggtttat aacctcatcc aaggtcaaac ctactgcaat cttggcagcc
    11401 aacttagcaa tcggatatcc tgtcgcttta gaagcaaggg ctgacgaacg tgatacacga
    11461 gggtttactt cgataacata atacttgaag ctgttaggat caagagctag ctgaacatta
    11521 catccacctt caatcttgag ggcacgaata atgctcaagc tcgcatcacg aagcatttgg
    11581 ttttcatagt ctgacatggt ttgcgcaggg gcaaatacaa tggaatcccc tgtgtgaatc
    11641 ccaactgggt caaagttttc catgttacaa acaaccaagg cattgtcagc tgagtcacgc
    11701 atcacttcgt attcaatttc cttgaaaccg gcaatcgaac gctcaatcaa acattgggta
    11761 acaggtgaca atttcaaacc attttcagtg atttcacgca attctttctc gttggcacac
    11821 ataccaccac cagtaccacc aagggtaaag gctggacgaa cgatgactgg gtagccaatt
    11881 gtcgctgcaa aggcaattgc ttcttctact gtgttaacaa tttcagattc tggaatgggt
    11941 tgctcaagct cttccatcaa ttgtttaaag aggtcacggt cctccgcttg gtcaatggca
    12001 gacaatctag taccgagaag ctctacacca agctcatcta agataccatt tttagacaat
    12061 tccatggcca tgttgagacc tgtctgacca ccgagtgttg gtagcaaggc atctggacgt
    12121 tccttacgaa gaatacgtgt cacaaactca agtgtaatcg gttcaatgta aaccttatca
    12181 gcaatttcct tgtccgtcat gatggttgca ggatttgagt taaccaaaac aacctcataa
    12241 ccttcctctt tcaacgacaa gcaagcctgg gtcccagcgt agtcaaactc agcagcctga
    12301 ccaataataa tcggaccaga accaatcacc ataatttttt gaatatcagt acgtttaggc
    12361 atagtttatg atacaaagcc cgtaaagaac acagtgaaaa taggaaactc ggcgcagacg
    12421 ccttcagcgt caagacgatg tttatctttt tcacacagtt cttagggcgt gttcacttcc
    12481 gcgaacaatg tatcttctcc tttctattcg tcgcctctca gggcgacatt aaataagata
    12541 caaaggacga atagaaagcg attgaatttt agaaaatcaa ggaaggattg acaatccaag
    12601 ttggtttctc tacattctga gctttccgtc cgtgttcagt tacataaatt ctccgacgag
    12661 cttttactcg ttcttagttt gattgtttaa aaacttccat catctcgata aactcgtcaa
    12721 ataggtagct agcgtcgtgt ggcccaggag ctgcatctgg gtggtattga acagagaaag
    12781 caggttggta tctgtggcgc acaccttcca ctgacttgtc attgatttct tcgtgggtaa
    12841 taatcaagtg ctctggcaaa tcctcgcggc tgactgcata accatggttc tggctggtga
    12901 agtctactcg tcctgttgcg atttcacgta ccgcatggtt gaatccacgg tggccaaact
    12961 tcatcttata ggtcttagcc ccgtttgcca ttgcaaagag ttggtgtccc atacaaatac
    13021 caaagattgg aatttttcct tgtacaccgc gaatcatgtc gagtgcttgt ggaacgtctt
    13081 ctgggttacc tggaccattt gacaacataa ctccatcagg attgagatgg agaatttctt
    13141 cagccgttgt cgaataagga acaactgtca cgttacagtt gcgtttagaa agttcacgta
    13201 ggattgagtg cttgagacca aagtccacta gcaccacgct caaaccaact cctggagctg
    13261 gataagacgt tttagtagaa acctgtttga tattgtctgt cggtaaaact gttgcttgga
    13321 gctggtccgt cacatggtcc atactgtccc caacatgggt caaggttgca cgcatagtac
    13381 catgcttacg gataatcttg gtaagagcac gcgtatcaat tcctgaaatc cctggaattt
    13441 tcttggcttt caaaaattca tccaaggtca tttggttgcg ccagttgcta gctctacgcg
    13501 cttcttcaaa aacaacgact cccttacaag ttggaataat ggattcataa tcatcacgat
    13561 taataccata atttcctacc aaaggataag taaaggtcaa gatttgtcca ttataagact
    13621 ggtctgtaat ggattcttgg tagccggtca tccctgtatt aaagacgatt tcgcctgtta
    13681 catcaatatc tgctccgaag gccttgcctt caaaaactgt gccatcttct aatactagaa
    13741 ttctttttgt catattttca cctctcgtgg acgctcactg gcgtctttta acgtcttgtg
    13801 ttttagttgg cgtttctact cgctagtacg gattctaaga ttgccattcg aacaaagaca
    13861 ccattggtca tttgttggac aatccgtgat tttggtgctt caaccaagtg gtctgctatt
    13921 tctacatcac gattgattgg agctgggtgc atgaggattg ctgtttcttt caaacgatcg
    13981 taacgttctt gagtcaagcc atgttgggca tggtagtctt cttttgaaaa tacagctcca
    14041 ctatcatggc gttcgtgttg cacacggaga aacatcatga catcaacctg atcaatgatt
    14101 tcatcaatgg ttacaaactg tccatagtct gcaaactctt gacttctcca ttcctcaggt
    14161 ccagcgaaaa agagttcagc tcccaagcgt ttcaaaatct gcatattgga tttggcaacg
    14221 cgtgagtggt ccaagtcacc tgcaatagca actttaagac cctcaaagtg gccaaattcc
    14281 tcataaatgg tcatcaaatc aagcaagctc tggctagggt gttggcccga accatctcca
    14341 ccattgatga tggaagtcgt aatcgttgga ctagcaatca attctctata gtagtcgacc
    14401 tctggatggc gaatcacaca gacatccact cctaaagcag acagagtcaa aatggtgtca
    14461 taaagtgtct cacccttatt aaccgagcta gtcttcacat caaagtcaag tcgttccaat
    14521 ccaagtttaa tctctgcgac ttcaaaggac ttatgtgtcc gtgtagaatc ctcaaagaag
    14581 agattggaaa caatcggatg gtcttcatag ggaagctggg ctccattttt aaactcaatt
    14641 cctcgcttga tcaatttcat tacttgatcg acagtgaggt cttccatgga caccacatgg
    14701 ttcaatgctt gttgattttc tgacatggct actcctttaa ctttctaagc ttcttcagta
    14761 atcagaactc tgtcttggtc atcaagttct gtcatctcta cgatgatttc ttcagaacga
    14821 ctggttggga tattttttcc aacgtaatct ggacggattg gcaattctct atgtccacga
    14881 tcgactagaa ctgctaaact cacacgcgca ggacgaccat gaccgacaat attatcaata
    14941 gcagcacgga tggtacgacc tgtatagagc acatcatcca ccaagataac ttcgcggtct
    15001 gtcacatcga cagaaaccaa agaagtatct tctccacttt taacatcatc acggaaaggt
    15061 ttagtatcca attccacaac aggaactgaa agattttcta actgcttcaa acgttcttgg
    15121 attcggtggg caataaagac accacgagtt ttaataccag ccaagacgat cttattcaaa
    15181 tctttgttgc gttcgataat ctcataagta atacgcgtaa tcgctcgttt gacggtcaat
    15241 tcgtctacaa cttcttttgt tttcatgaca aacctccaaa aagaaaagtc tccttaaaca
    15301 aggagacttg aaatttatag ccaagcgagc cctactgcac acagtataga cttcaccctt
    15361 ctactttatc gcgctccttg cctgcctcac gggacaggtt taaaggaata tttagttatc
    15421 atttactata gcacaaagca tgcttaaaat caagcaaaaa gtttcaatgt agcatcttac
    15481 aaattgctaa aatcatataa ttgtgggtac tggtcacact ctggattttt tggatggcaa
    15541 atggctcttc caaaataaat catggcctga tgggcagcta accactgctc aggcggcaag
    15601 atatccatga cccgcttttc cacctcaagt ggcgtcgctg attttttgac aatatcgtgg
    15661 tgtttgcaaa tacgctccac atgagtatcc actgcaaagg ctggaattcc aaatcctaca
    15721 ctcatgacaa cattggctgt cttgcgacca acacctgcca aactctccaa ttcttcacgt
    15781 gtctgaggga cttgaccatc aaaatcgtct agtaactgtt gggcacattt tttaaggaat
    15841 ttagctttat tccgatacaa tcccaagcga gaaatatgtg aagcaatctc actctctgtc
    15901 gctacagaca tagcttgggg tgttggaaag gcaacaaaga gacctggtgt ggccttattt
    15961 accgctgcat ctgtcgtctg ggctgataac atgaccgcaa ccaggagttc aaaatgattg
    16021 gtaaaatcaa gactaggctt ggcatctggg aagagggcaa tgatttcttc tagcaccttt
    16081 cgtgctcgtt tttttgacaa gaccattatt catctccgtc aaatagtcct tgtaagccag
    16141 caaaaggact gttttcttct ttctttactg ctttttgagc ttggtattct tcctctgtca
    16201 tgatttgcca gtcatttcct gagataaatc cttgaccagc ttcttcttca gccgtcaaga
    16261 ccttgatagg aatgtttagc aggatattgt ctgatacact ctcagcaagg tcaagctccc
    16321 cattttcgat gggcaagacc aagtcatcat ctaaaacttc ttgatctagc tggttagttg
    16381 cgccttccat gaaaacttcc gtgactggat aagattcaac taactcaact ggctccatac
    16441 tgcgactcga agcaagaaca atggtataag atagttgata atctaagaaa tacatacggt
    16501 cttcatattg tactttccca actgcaagga tatcttttac atctaaaatt tcttgattac
    16561 gtgcacgcag gtcatcaact aaatctaacg tttgttcaaa gttcaaacct tcagactgct
    16621 tacgaatttc ttgaatattt aatttcatac ttcctccata aagatttact ctcttgatta
    16681 taccatgaaa aggctacaaa tcagcacacc aaactttgta attaaaattc aaaattttaa
    16741 catatttact atgatagttt tattttttag tgctatacta tagggaaaga gtacatcaga
    16801 tcaaggagga tgctcacatg gaagacaaga aactcattca actcctatcc aagttaaata
    16861 aaagctacca aaactgtaaa cagggtacgg cagatgatat tcgactacaa gagctgctaa
    16921 acactactat gcaagagctc aaaaaaacgg aacagttgaa caacagtatc ttaattgatc
    16981 ttgagaaatt ttaccaacct accagtcttc tgattggact gggtagccta aaactaaacg
    17041 atcaagcacg cactgcttgg cgaaactatg ataaattcca ttacgatcat gtcaaacacg
    17101 tactaagtct ctatggacct gtttttgaat tttagagcat agaatttcca gttttctgtt
    17161 gacaaaattt ccttaaaggt ataatataaa gatactaata ctcggaggta agggagacat
    17221 gaacaactaa gtctatcaaa taaagaacct ttatttagta gatcttgttt ttgtctcttt
    17281 ttgtgtgctc ttttatgctc tttttctggc atgttaatag agtttttttg acatagactt
    17341 tgggctctac taggtaaagt agagcttttt gttatgcact atgaacattc tagaaaggga
    17401 aatcatatga taaaaatcaa tcatctaacc atcacacaaa acaaagattt acgagatctt
    17461 gtatctgacc taaccatgac catccaagac ggggaaaagg ttgctattat tggtgaagaa
    17521 ggaaatggca aatcaacctt acttaaaatt ttaatggggg aagctttgtc tgatttcact
    17581 atcaagggaa acatccaatc tgactatcag tcactggcct acattcctca aaaagtccct
    17641 gaggacctaa aaaagaaaac tttacacgac tacttctttt tagattctat tgatttagac
    17701 tacagtatcc tctatcgttt ggcggaggaa ttgcattttg atagcaatcg tttcgcaagt
    17761 gaccaagaga ttggcaatct atcagggggc gaagctttga aaattcagct tatccatgag
    17821 ttagccaaac cctttgagat tctattttta gatgaacctt caaatgacct agaccttgag
    17881 acagttgatt ggctaaaagg ccagattcaa aagaccaggc aaaccgttat tttcatttcc
    17941 catgatgaag actttctttc tgaaacggca gacactattg ttcacttgcg actggtcaaa
    18001 caccgtaaag aagcggaaac gctagtagag catttagact atgatagcta tagtgagcag
    18061 agaaaggcta attttgccaa acaaagtcag caagctgcta acaaccaaag agcctacgat
    18121 aaaaccatgg aaaaacatcg gagagttaag caaaatgtag aaactgcgct tcgagctacc
    18181 aaagatagta ctgccggtcg cctattggct aaaaagatga aaactgtcct ctcacaagaa
    18241 aaacgctacg aaaaggcagc tcagtccatg actcaaaagc cacttgaaga ggaacaaatc
    18301 caacttttct tttcagacat ccaaccatta ccagcttcta aagtcttagt ccaactggaa
    18361 aaagaaaatt tgtccattga cgaccgagtt ttggttcaaa aactacaact aactgtccgt
    18421 ggccaagaaa aaatcggtat tatcgggcca aatggtgttg ggaaatcaac tctgttagcc
    18481 aagttacaga gacttctgaa tgataaaaga gagatttcac ttggttttat gccacaagat
    18541 taccacaaaa aactgcaatt ggatttatcc ccaatagcct atctcagtaa aactggggaa
    18601 aaagaggaac tacagaaaat ccaatctcac ctagctagtc tcaatttcag ttatccagaa
    18661 atgcagcatc aaattcgctc cttatctggc ggacaacagg gaaaactcct gcttttggat
    18721 ttagtcctgc gcaaaccaaa ctttctcctg ctggatgaac ccacacgaaa cttttctccc
    18781 acttctcaac cccaaatcag aaaactcttt gctacctatc caggcggtct catcactgtt
    18841 tcgcatgacc gtcgtttatt aaaagaagtc tgctcgatca tctatcgcat gacagaacac
    18901 ggtttgaagc tagttaattt agaagattta taaatttgca acatagcaaa aatccagaga
    18961 cgacctctgg attcttttac atctgtttta aacgttcaat ccgttctgag ataggtgggt
    19021 gggtataaaa gagtttttgg aaccccccac ctttcttagg atcattgata taaagggcac
    19081 tgctagcatc atcgacgtgg cgactcatag gtttgctatt gtccaactta tctagggcat
    19141 taatcattcc ctggggattg cgagtcagct cgacactaga tgcatctgcc agaaattccc
    19201 tctgacgaga aatagcgagc tgaaccaagg ttgcagcgag aggtgccagt acaatagcta
    19261 gtagggaaac cactagcata atgatttcaa gaccatttcc atctcggtca tcatcacttc
    19321 gtctgcgacc tgctccaccc caccacatca tacgacctgc catactagaa agcatggtga
    19381 tagcactagc aagggcaact gcaatagtcg aaatacggat atcataatta cgaatatgac
    19441 tgacttcatg tcccataaca gcttctagtt cttcacgatt catgatagct agtagacctg
    19501 aagtcgcagc aacagccgca ttttgaggat tagaacctgt cgcaaaggca tttaaggctg
    19561 gatcatcaat gatgaaaaca cggggcatag gaatctgagc gaccagagcc atatcttcca
    19621 ctacatggta gaggtctggt gccgtttgct catccacctc acgcgctcca ttcatggaca
    19681 tgacaatctc tgtcgattga aaaatcatag acaaagcgta gataaagccg ataatcagtg
    19741 caataaccaa accaccaagt ccagatctta taaagagata accaaccgca taaccaacaa
    19801 gagctaagag taggaaaaat accagcaaca aaatccaggt ttttcgttta ttgcttgcaa
    19861 tttgatcaaa caacatctta gtcacctaaa ccgctaaaat caactttagg aaccgacttt
    19921 tcctcttcag gtgtttgaag gaaatctgcc gctttaaatc caaacattcc agcgataata
    19981 ttgctcggga aagtttctaa ttttacattg tagttgctga caacactgtt atagagttga
    20041 cgagagtaag aaattttatt ttctgtgttt gtcaactcct cttgcaattt aacaaagtta
    20101 gcactagctt tcaaatctgg atagctttct gcaactgcaa aaatacctga aacctgacga
    20161 gtgagggcat cactggcttt catagcttct gctggtgaag tcgctgccgc cacttggtta
    20221 cgtagttctg ccaccttttc aagggtagaa ccttcatatt tggcataacc ttttacagtc
    20281 tcaatcaagt ttggcaagag gtcattgcga cgtttcaact gaacatcaat ctgactccaa
    20341 gcctccttgg tttgcatacg atttttaacc aaaccgttat agctaacaat cacaaaaata
    20401 acaataagag cgataactcc aagaataatc caagtcataa tataagtcct ttctgctttt
    20461 agattagtac cagtatatca aattttctat gattgtggta aaataagatg atactaaaga
    20521 aggaaataac tatgaaacca aaaacatttt acaacttgct tgccgagcag aatcttccac
    20581 tttcggacca gcaaaaagaa caatttgaac gttattttga gctcttggtc gagtggaatg
    20641 agaagattaa tttgacggcg attacggaca aggaagaagt ttatctcaaa catttttacg
    20701 attcgattgc acccattctt caaggtttga ttcccaatga aactatcaaa cttcttgata
    20761 tcggggctgg ggcaggattt cctagtctac caatgaaaat tctctatccg gagttagatg
    20821 tgaccattat tgattcactc aataagcgca tcaacttcct acaactcttg gctcaagaac
    20881 tggatttgaa cggagttcat ttctaccacg gacgtgccga agattttgcc caagacaaga
    20941 acttccgtgc tcaatatgat tttgtaacag ctcgtgcggt tgcccgtatg caggtcctat
    21001 ctgaattgac tattccctac cttaaggttg gtggcaaact attagcactc aaggctagca
    21061 atgcgcctga ggaattatta gaagctaaga atgccctcaa tctccttttt agtaaggtcg
    21121 aagacaatct cagctacgcc ctaccgaata gagatccgcg ctatatcaca gtggtagaaa
    21181 agaaaaaaga aacaccaaat aaatatccac gtaaggctgg tatgccaaat aaacgcccac
    21241 tttaaatttt ttagtaaaca aatgtttaca aaatcagcct cgctctttta tttctaggct
    21301 cgggaaaaaa tgatttacaa aatcattttt ttctgctata ctatcctaag caaaggtttt
    21361 taatgtcatc ccgtgaggtg acgaagacgc agaaatattt aaaactcttt aaaatctaaa
    21421 ttttaaagaa gtcttactct gagggcctat tgctgtaaaa taatgggctc ttttttgatg
    21481 cccaaaagtg aggtttatat gaaacaagaa tcaactgttg atttgttact agacgttgac
    21541 caacgtcctt cggctggaaa aggaattctc cttagtttcc aacacgtttt cgccatgttt
    21601 ggtgcgacca tcttggtacc attgattttg ggaatgcctg tatctgttgc cctttttgct
    21661 tcaggtgttg gaacactcat ctacatgatt gctactggtt ttaaagttcc agtttatcta
    21721 ggttcttcat tcgcctttat cacagctatg tcactggcta tgaaagaaat ggggggggat
    21781 gtatctgctg ctcaaacagg ggttatcttg actggtttgg tctatgtcct tgttgctacc
    21841 agcatccgat ttgtaggaac aaaatggatt gataaactct tgccaccaat cattatcggt
    21901 cctatgatca tcgttatcgg tcttggactt gcaggttcag ctgttaccaa tgcaggtctt
    21961 gtagcagacg gaaattggaa aaatgctctg gtagccgttg ttactttcct aattgctgcc
    22021 tttatcaata caaaaggaaa aggcttccta cgaatcattc cattcctctt tgccattatc
    22081 ggtggttacc tcttcgcgct aactcttggt ttggttgact ttacgcctgt cctagaagct
    22141 aactggtttg aaattcctgg tttctacttg ccatttagca caggtggtgc ctttaaagag
    22201 tacaatcttt actttggtcc agaagccatc gctatcttgc caatcgctat cgtaacaatt
    22261 tctgaacata tcggagacca tactgttttg ggtcaaatct gtggccgtca attcttaaaa
    22321 gaaccaggtc ttcaccgtac tcttattggt gacggtatcg caacttctgt ttctgccttc
    22381 cttggtggac cagccaatac aacttacgga gaaaatacag gggttatcgg tatgactcgt
    22441 atcgcttctg tctcagttat ccgtaacgct gccttcatcg cgattgccct cagcttcctt
    22501 ggtaaattca ctgccttgat ttcaactatt ccaaacgctg tacttggtgg tatgtcaatc
    22561 cttctctatg gggttatcgc cagcaatggt ttgaaagtct tgattaaaga acgtgttgat
    22621 ttcgctcaaa tgcgaaacct catcatcgca agtgctatgt tggttcttgg acttggagga
    22681 gctatcctta aacttggtcc agttacactt tcaggtactg ccctttcagc catgacagga
    22741 atcatcttga acttgatctt gccatacgaa aataaagact aagagtctaa atacacctaa
    22801 tccactcaga cagctgagtg gatttttcgt atactataat aaaagtgtct taacaaaatt
    22861 attaaaatca aaaaacgtat aatatcagat attctaaaac cttgatactg tacgtttt
//
LOCUS       DAVEHY010000034        22838 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVEHY010000034 DAVEHY010000000
VERSION     DAVEHY010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.034"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(171..395)
                     /locus_tag="VUZ44_001627"
     CDS             complement(171..395)
                     /locus_tag="VUZ44_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEU0320502.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFILLLTFMVITYK"
     gene            complement(400..579)
                     /gene="asp4"
                     /locus_tag="VUZ44_001628"
     CDS             complement(400..579)
                     /gene="asp4"
                     /locus_tag="VUZ44_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEU0320503.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(581..1918)
                     /gene="gtfB"
                     /locus_tag="VUZ44_001629"
     CDS             complement(581..1918)
                     /gene="gtfB"
                     /locus_tag="VUZ44_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEU0320504.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QERLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(1911..3422)
                     /gene="gtfA"
                     /locus_tag="VUZ44_001630"
     CDS             complement(1911..3422)
                     /gene="gtfA"
                     /locus_tag="VUZ44_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HEU0320505.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLRDIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(3434..5806)
                     /gene="secA2"
                     /locus_tag="VUZ44_001631"
     CDS             complement(3434..5806)
                     /gene="secA2"
                     /locus_tag="VUZ44_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEU0320506.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEGPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKEYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDMIYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(5799..6239)
                     /gene="asp3"
                     /locus_tag="VUZ44_001632"
     CDS             complement(5799..6239)
                     /gene="asp3"
                     /locus_tag="VUZ44_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEU0320507.1"
                     /translation="MIITQRQSIHWGEVGGTYMYGSTVSYYPDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(6236..7771)
                     /gene="asp2"
                     /locus_tag="VUZ44_001633"
     CDS             complement(6236..7771)
                     /gene="asp2"
                     /locus_tag="VUZ44_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEU0320508.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGVKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(7755..9335)
                     /gene="asp1"
                     /locus_tag="VUZ44_001634"
     CDS             complement(7755..9335)
                     /gene="asp1"
                     /locus_tag="VUZ44_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEU0320509.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFGPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRIQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(9345..10562)
                     /gene="secY2"
                     /locus_tag="VUZ44_001635"
     CDS             complement(9345..10562)
                     /gene="secY2"
                     /locus_tag="VUZ44_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEU0320510.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRIILPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSYSKKLGLSSTAIEIQDRR
                     KMYLTLLIAVIQSLAVSLSLPVQSSYSVILVVLMNTLLLIAGTFFLVWLSDLNASMGI
                     GGSIVLLLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSL
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            complement(10619..11296)
                     /locus_tag="VUZ44_001636"
     CDS             complement(10619..11296)
                     /locus_tag="VUZ44_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU0320511.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARYIVE
                     VFSKKISDCVLAGLDISVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(11281..11523)
                     /locus_tag="VUZ44_001637"
     CDS             complement(11281..11523)
                     /locus_tag="VUZ44_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0320512.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDASTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            complement(11523..12719)
                     /locus_tag="VUZ44_001638"
     CDS             complement(11523..12719)
                     /locus_tag="VUZ44_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU0320513.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVHSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(12728..13948)
                     /locus_tag="VUZ44_001639"
     CDS             complement(12728..13948)
                     /locus_tag="VUZ44_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEU0320514.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(13979..16423)
                     /locus_tag="VUZ44_001640"
     CDS             complement(13979..16423)
                     /locus_tag="VUZ44_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEU0320515.1"
                     /translation="MNKTIVLAGDRNYTRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSIYLEEKSLAAVKDTDGITFNTGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLTANRYRDLWWEFHDLEWSQILQHHMGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTVMGPML
                     QELAKKYKNVKLYPEVKIDQFEKLKSQMDVYLDINLHNSTSEVVKEISSLNKPMLAFY
                     TSQNGNHGQHLYSSEHPERLLQAFHALIKGETLGEPEKPIKVIGIDQTLDYVIKNKSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHVDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(16433..17443)
                     /locus_tag="VUZ44_001641"
     CDS             complement(16433..17443)
                     /locus_tag="VUZ44_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU0320516.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIS
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSNARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSNLSTAKFIV
                     DQGLGFMADSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     ID"
     gene            complement(17472..18347)
                     /locus_tag="VUZ44_001642"
     CDS             complement(17472..18347)
                     /locus_tag="VUZ44_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0320517.1"
                     /translation="MENELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVVAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(18387..19265)
                     /locus_tag="VUZ44_001643"
     CDS             complement(18387..19265)
                     /locus_tag="VUZ44_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HEU0320518.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLFSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILNDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLFVKRRD"
     gene            complement(19262..20662)
                     /locus_tag="VUZ44_001644"
     CDS             complement(19262..20662)
                     /locus_tag="VUZ44_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000543101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU0320519.1"
                     /translation="MHALVDAMSERITLLANMGYPLEKHLAVYRQMLEVSLANGQASG
                     LSDTAMYKEFEMKKRLLNQLTVQESSEKKAIVLAANYAYVDQVLTTIKSICYHNRSIR
                     FYLIHSDFPNEWIKQLNKRLEKCDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFV
                     QEDKALYLDCDLVVTKNLDDLFATDLQDYPLAAVRDFGGRAYFGQEIFNAGVLLVNNA
                     FWKKENMTQKLIDLTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQ
                     LPEGQDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIY
                     PIKEPFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNG
                     IHYLVDVDNELVETSQVLLDINHGEKTEEIINQFARLGKTILSFENTKTYEAGQEVYA
                     VDQVQAMIEKLREISK"
     gene            complement(20737..21345)
                     /locus_tag="VUZ44_001645"
     CDS             complement(20737..21345)
                     /locus_tag="VUZ44_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0320520.1"
                     /translation="MDDKITVIVPVYNVENYLRKCLDSIITQTYKNIEIVVVNDGSTD
                     ASGEICKEFAEMDHRITYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIELDYVET
                     LYKKITEYQADIAVGNYYSFNESEGMFYFHISGDSYYEKVYDNVSIFENLYETQEMKS
                     FALISACGKLYKARLFEQLRFDMGKLGEDGYSIKRYIYYRKR"
     gene            complement(21406..>22838)
                     /locus_tag="VUZ44_001646"
     CDS             complement(21406..>22838)
                     /locus_tag="VUZ44_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU0320521.1"
                     /translation="ASASASTSASASAGKSRQQLPNTGTEVSKSSVASTSASESASTS
                     ASASASTSASASASTSASASTSTSASASASTSASASASTSASASASTSASASASTSAS
                     ASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASAS
                     ASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASAS
                     TSASESASTSASASASISASESASTSASASASTSASASASTSASASASTSASASASTS
                     ASASTSASTSASTSASTSASESASTSASTSASTSASASASISASESASTSASASASTS
                     ASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSAS
                     ASASTSASASASTSASASASTSVSNSANHSNSQVGNASGSTGKSQKELPNTGTESSIG
                     SVLLGVLAAVTGIGLVAKRRKRDEEE"
BASE COUNT         7158 a         4887 c         3714 g         7079 t
ORIGIN      
        1 acaacctcaa aacggtgttt tgagctgact tcgtcagtta tatctacaac ctcaaaacgg
       61 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa
      121 aaagaaaact tcagaccaat ccacaaaagg tgaatatctg aagttttctt ttatttataa
      181 gtaatcacca taaaggttaa tagtagaata aataaagcca aactcaccaa taaagtgagc
      241 accttgacca aggtgttgct ctgccagtag cttggtttac caatattact agtggcatcc
      301 atggaaaata gttgattttg acggggttgt atagttacca atacaatcaa agcaagagat
      361 aggataatag ctaaaacaat tagtatttca atcatagatc tacctcaaaa ttcccagcaa
      421 agtaaagagc aaaccaatca gaatcattaa gcccagtaaa agtgaaaaag ttttactaat
      481 cttctcccct cgggtttctt tttccttctt gatgggtttt tgtttcaact cttccatgcg
      541 gccttcaacg tctttgtaaa ataaatcttc ctctgacatg ttagcctcct aaaacagttt
      601 gcatggtttc ctgatatctc accaagtcaa cataatttgc atgttggcct tgtttgccaa
      661 gtgcctgacg catttgatca acatctgaaa gggccaattt aatggtctca accaaagcag
      721 caacttcact actttcaaat agatggtctg gagcgatata aagtctattg tgcaccgtct
      781 gattaaagcc aagaatcaag agattgtgct caaaggcctg acgcactgcc tgtagcaact
      841 cattactgtg gtttatatcc aagtaaatat ccgacagttg atacagctcc tgaatcttct
      901 gtggactagc gttctggtaa aggaccacat taggatagcg aagcatgtct aagagcttag
      961 aagacatctc tgtcaccgct gcaatacgga aagtgacatc aggcaaggct cctgcgattg
     1021 cttctacttg ctcaatctga tctgaattgg tcaagattaa ggcatctcgt cttaggaaat
     1081 tatcacgttt gaactggtaa tgataaccca agtgcacaaa ctgatcatgg tatttctcgt
     1141 cagttaactc taaagcgcgc tcataagtcg ccttatttgg aatgatgatc ttcttagtac
     1201 gcacattatc actttccaaa atcaactgca tattacctgg aatggcatca tagagacgtt
     1261 cctgccatac caagacatcc gagccagatt tatctggatg atggaaggaa accaagaaag
     1321 gagtcgctag agtattaaag ataagctgac tggtatctat ttccaaatct tgcaaaaaga
     1381 aggtgataaa ttcaacttta tttgcaaagt aacgcatgga ctgaccaggc aaagtcaata
     1441 agatatcacc cgtcacatgg ttttccagta aaacttgttg gccattgaca tcttggtaaa
     1501 ctgtcataat cggctcgcta tctgcgctat aagtggtttt agcaaagcaa gcaccaaagc
     1561 gattgtagtg gtcaacctga cgtactcgac cttctaggtc tttccagtct acctgtttaa
     1621 ccaagcgagc ctgcattcca tcaacataat gaatgacagc cctctcctgc gtcacatctt
     1681 caatacaagc agactgatta tctcctaaaa tttcccaaaa atctgagacg ggaacttggt
     1741 taaaatagag aggttttcca tcctcgtaac ctagataata ggtaaaagga gaaagcagac
     1801 catcaggcag aaaaccatct gcatcgatga ccactccaag ttgagaaaga ccagtagcga
     1861 ctagactttc atgtaaatct cgactttctt gactgtaact atcataaagt tcaatcatgg
     1921 agcacctcct ctactgtttt cttccacttt tctaaaattt ctttggtcaa gaagccttct
     1981 gcaatttggt aagaataggc acgcatagct tccaaacgat tttcttgata caattgacaa
     2041 atcttagcgg cataagcttg cttgatttgg tcttctacat ggtcagatga acttggaatc
     2101 aaataaccat tttgcccatc ctctataaag gtctgattac cataaggcac atcaaaacca
     2161 attagaggta gacctgaacc aatagcttcc atcaaggtca gaccaaatcc ttcgctggta
     2221 gaagccgtta agtagacctc atactggcta taaatctgcg aaagttccgc atgccccttg
     2281 agttggatat agtcctctgc ctgatgattt gcaataatgt ctctaagcag agaatcttct
     2341 ccaccactac catagatatc aaaggttagt tccggtaact ccttatgagc ttcaatcaca
     2401 gctttcacaa gccaatcaat gtgcttttct ttggcaagac gtgaagccgt aatcaatgaa
     2461 aatggtttgc gcccttgact tgaatctgtc aaggaatcaa tactgcctac aggaatggta
     2521 acaatctttg gctgatgctg agtatatttg gcaaattgct cttgtagaac ttcattttgt
     2581 ctatcagtag acacgataaa gaagtcaacc ttatctgcat tggtaaactg atagtcataa
     2641 tagttattcc aaaggatgta gtcctcattt gtagcatttt cactataatg ctccgcatga
     2701 acaactaccg ctaaatgtgc tgtctgtgct tcctcaaaca caacctgacc aatgcctgtc
     2761 tccctatcga gaatgaccaa atcagactta ttcaaattca aagatttcat aaaggcacgc
     2821 acaaaagctt gctttccata gaaaatctta tccttgaaat gataaacttc ttccttccct
     2881 tgattcatca agatatcata gactggagtc ccgtcttcat tataaaaagt tcgttggtat
     2941 aagactgcaa cattgtcctt gggagcaaaa tactcgctac aataacgcgt ataagaaaag
     3001 taatccttcc gaatcaggtt tcccttaaaa acatactcgg catgttgaac caagtccttg
     3061 ttctcatcaa ccaaataaca ggttacaaac ttatcttggt caaaaaagaa tacacgtaaa
     3121 accttgccat ttttttctct gtgactttct tcaccaccaa agtaagccaa gacatcatcc
     3181 actgtcacgc tagtaggtgc aattttgata tctgtgaaat gattataaag ccagataacc
     3241 tgattatcat caaaaccaat attggctgtt aagtgctgaa tattatcggc taaaatcata
     3301 tctgtaaaga taaacttaga ggacagattt aatttccgaa aaacaccagc acgataggct
     3361 tgagcgtatt caacaccgct actagcccaa ccaattccta aatttatatt gtaaattgtc
     3421 atattttctc ctcttatgga aaatgagtca cgatttcacc ttttggagtg acctcaacca
     3481 gccccatcag gagattacgc accatatccg cacggatttg ttctttcata gcttcaaagc
     3541 ccgcgtaggc ttcttgatag tactctacga ttggattttt ctgactagca gattgaccac
     3601 cgatagccat ggatagctgt tgtagatagt ctacctgctc tacccagttg tcatcaatgg
     3661 ctttaagcag tgaaagtcgt aaaaactgtt catataagtc atgttgatta agtaattctt
     3721 tcttttcaga aagttcttta tcaatcacct gcttcataaa gctacgaact gcagttttgt
     3781 cagttacatc tatataatct ggaacctctt taacatgaaa actaatattg gtcacaataa
     3841 agtgaaacaa taattcacga ctagcatagt gatcagccgc tacctcttct gtatatctct
     3901 caatgatatc cacaacaaca tcctctaagt cacgagaacc atctattaga cgattacgct
     3961 ccttgtaaat catatcccgt tgaatattca tactttcagc atattctaga gtctgacgac
     4021 gtgccgaacg gccagcacta tcactagcat gttgagcctt ttcgactagt ttccggtatt
     4081 tacgaccttt caatacttcc ggttgagtca tatcttgaac ctgatagtct ttgtactttt
     4141 tatgcaccca agatggacca aatttcttga taacatcatc ctctaaggat acaaaaaatt
     4201 tactcatacc aggatctccc tgacgaccag aacggccacg aatttgtagg tcgatccgct
     4261 gactttccat ccgctcagtc ccaataacaa tcaagccccc aagctctgcg actcctttac
     4321 caagcttgat atccgtacca cgtcctgcca tagaggtagc cactgtcaca gcccccatct
     4381 gacctgactc ggagataatc tgagcctcac gcgccgcatt attagcattt aggacattat
     4441 gggcaatccc ttcacgaaac aagagagacg aataaagttg agacatttca actgagccta
     4501 caaaaacgag taaaggattt cccttagcat ggtattcctt gatgtactcc aaggatgcat
     4561 acactttttc aggtaaagtg atatatagat tatctggata gtcaatccgt tgtctcggac
     4621 gattggttgg aatgcgtact acagacatat tgtaagtttc aataaactct ttttccgcga
     4681 ccttacctgt ccctgtcata ccagatatct tattaaacat cttaaaaaga ctctgatagg
     4741 tgatcgaggc catagcccgc gtctcaggag ataatttgac atgttccttg gcttcaatag
     4801 cctgatggag acctccttga agtttagtca tttccattag acgccctgtt cccttatcaa
     4861 ccagtaccat ctcatttcca cgaatgatat agtccttatc tttagtaaag agcttatgag
     4921 ctcgaatcgc ataaaccaaa tgacgagcaa aagacgcatg ctcttccttg tataaattat
     4981 caatccctag gaaattctca gcagacttgg cccccttagt agtgagccaa acctcctctt
     5041 tctcctcttt aaagatataa tcctctcctt cgaccaaggt tgttacaagt gtatcaatga
     5101 tcgcatagta attagactga acacgaggag aacccgcaat aatcagagga gtttgtgcac
     5161 tatcaagcaa gatatcatca atttcatcaa taatcacata gttaaacggt cgtaaaaact
     5221 taccttcttc attcgaggct aggttatcat ttagataatc aaaacctaaa ttactattgg
     5281 ttgtgtagat gatatccgaa gcatagataa gcttcttttc ttcagctttc atttccttct
     5341 ttggaccttc cgtaaatggt acaccaatgg tcaatcctag aaaacgataa acttggccca
     5401 tttcctcggc atcacgcttt gataaatact cattaggagt cacaaccatc actccttctc
     5461 ctgaaaaagc gttcaaatag acaggcatgg tagctgtcaa ggtcttacct tcccccgtat
     5521 tcatctcagc aacatttcca tagtgcatga caatagctcc catgacttga acatcatagg
     5581 ggaacatccc taaaatccgc ttatctgctt cacgcaccac agcaaaagct tcaaccaaaa
     5641 tatcgtctag actttctccc tcggaaagac gctgacgaaa ctctactgtt ttagctacta
     5701 attcttgatc cgaaagagag gacatcttgc ctttcagggc attaatctgc tttaaaatct
     5761 ttttcacttt cctaagctgg aaatcttgac ctaaacgtct aaacacttct gatctccttg
     5821 atagaaaaat gataaaaagt taaggactca aatccagcac ttaaaagaga aacttgataa
     5881 gtataactat cttctggata agtaaatatg aaatctttcg ctttttctac ctttttttct
     5941 aaaatatcac catagcggtc aaaaaaagtt atcttggtat aaactccatt ttcaggctga
     6001 caatcaaaaa ccagtgatag ttgatactcc tgctttcttt ttaataaggg aagctgaggt
     6061 tgggttcgtg cagcctggta attgacacta gaaaaccaag tctttagaat ctcaccagat
     6121 ggcaatagag gattatacag acgaacactt ttgtcagggt aataagatac agttgatcca
     6181 tacatataag tcccaccaac ttctccccaa tgaatagact gtctctgtgt aataatcatc
     6241 ttttctccct tccaaaacca gtctctaaga ccattctata aaagtgcaaa aaccaagaaa
     6301 tattggtatc tgtatcatca ttgtgtcgtc cagcagttcc tttagataaa atcttcacac
     6361 ctgtattaca cagataagac actaattgtt cataggcttg tggatccatt tcttcatctt
     6421 tcatatagga taaaccaaag gttgtctttg aaaaatttgc ttgtttaaaa attttccaaa
     6481 aacgctgatc caactccgtc atatcttgag aacttgtccc acctgtatga tgaattaaac
     6541 aatcaaaagc taagttagag acacccggtg cgtccaaacg tccacgacta gctatagttc
     6601 ctaaattagc caagggctta ccaactatga tggcatgggg ttcaaaagaa gcaccataat
     6661 agagagccgg aaacgttccc atagaaagac ctgataaaat caaatcctta tgatcaaagc
     6721 ctaaataatc aagatagtga gtgatcgtat cctttacttt tccctctagc tcatccgttc
     6781 cgagataaaa agctcccccc tctaaacgtg gatcagaaaa taaaatgaag ggacatccaa
     6841 gagttttcat cataaagtaa ccctcgaatc cttctgcagg tcgataacct gcaaaataga
     6901 cagtcaaagg cggtttaaaa tcacctggat ggaagaaata gtttatttca tcacgcttgg
     6961 aatcatgtag gatatttcca ccaagtacaa acttaccaaa ttgttttcga ctccatcgtt
     7021 ggtgaagatt acctagtttg atagttccac gacctcttgc ttcaacagat atcgagagaa
     7081 agtagtctcc gtctcgacta tccataaaaa gtgcttgctc caagtctttt tcagatacta
     7141 ttacttcttc aaagaaatca tcaacagacc cactccacat tttacggatt actaaacgaa
     7201 agtcacaatt gccttccttc tcatattcaa gccacaactc aatagggagt gttttttgca
     7261 ccataatatt ataagcccaa taggcaagct gggcaaaatc ttgcccaaac tcaccttcca
     7321 aactgacata atccaatcct tgataagaaa tagctcctgt aaaatttgga ttgacttgta
     7381 tcgtcggagg aaagagttta tcaccatacc caccgccaaa aagagattta cttaaatcat
     7441 tgattagttg ttggggactt aaaaaatcaa ttgcttgtgc acatcgtttt tttagaaaat
     7501 ccacaacctc tctatcattt atttgtagat tctggttata gaacaaagta taaggttcaa
     7561 aatattttac ataggaaaat aagtctctgg aatactgacc atcttctatt aaaactgcat
     7621 gaaaacggtt aatatcctct ttttcaatta tttcacgaag ggtttttgat gagtttgggt
     7681 aaaaataata ccaactcata ttttcaggta tgtcatagtg attttcccaa ttggcaagtc
     7741 ctatctgtaa aatattaagt tcctttgaca tttttaacct cctctatcca tttctctaat
     7801 tttccaagaa attgttgtcc tgtgtgctcc ttaatcttat caattgaata tatcaaggac
     7861 tcattccact ccttcaacct atctgtgtaa taatgtgcag ccttagaaaa ttctgtaaca
     7921 tctgctaaca aataaccatt ttttaaatgt tcaacataga cggtttcaac taggttgatt
     7981 tgaggaattc ctgcactaat cccagctatc tgtgtgtaga gatgaggatg tctatttaaa
     8041 tccacaatca aacggacaaa ttctagtgtt tttatcaaat ctaactcatc attcaagttg
     8101 acaaactgta tacgtaagtc ctggtgttga ttttcttcca gaggattttc tgcatcacca
     8161 taatcaatcg cctttcccag attttcggat tgaatgtttt cttggatgaa agactcaaca
     8221 atcccttcaa cctcattcat ttgctcctga ctagcagcaa aggctccaaa aatcacctca
     8281 gtatccttat tttcagcgac aaaggacaag acttgaagca gagcttgatt atcaatcccc
     8341 tgctcaaaat ccagttgaaa ataaatgatg gattctttct tagtttggct tcgtcccaat
     8401 cgtaatcggg tgtcaaaaga tgataaatga taacattgat gcattcgttc aggatacaac
     8461 tcctgcaaca atcgtaaact atcctctcta tccaccaaaa tcaaatccga tttttcaaaa
     8521 gttacatcta aatccctaaa ggtatcttga ggattacgtc caatgaacag actcaacagt
     8581 ttaggattag tactaggtaa acgatctagt accaactggt catgatgaga atgagaagga
     8641 agcataaaaa tatcctgatc cttcacatac gtttgcagat aattctcaaa aaattctgcc
     8701 accagatctc ccatattttg ataggtaagc attttaaagc gataacccaa aattggattg
     8761 acttctacct gtcctccttc ttttaaacgc tctctaaatt gccaaactcc cttaggattc
     8821 aaatattctt gataggctgc ttgcccatct tcaaaaaaaa taatactcga tataaaccct
     8881 cgatcatcca tgatatggtg catatgtatt tgaccattcg gtccaaaata ctgtatatca
     8941 ctgatgaagc cttcaactcc atgttcaacc ttagcaaatt tcttcccatt tttttgaacg
     9001 ataatcgtaa agggactata aataaattca cagtcatcat cccactcaat atctctaatg
     9061 cttaaaactt gggtatggag attatgaaaa tcttgcataa catcaaaaac ggaataagta
     9121 tccgtttcta acacaccatg tctatataaa aaataacgta gatgaggctg gtaagctaat
     9181 actaatagac gagaatctat atcttgctct tgaaagagcc gaatctggtg aaaggtatca
     9241 tcaaactcta gacgaaaatg agaaaaatac catggagtga tatctgcatg ccatgttctt
     9301 tctgacccat accaagctgg aataaaataa tacataaaag tctcctaaat caaaggttta
     9361 taggtctcat ttagccttaa agccttgacc tcgtctctaa tcgtaaaaat catgcctcca
     9421 aacatcataa acaaacctgg aatcattgcc aatcgtaata acttttcatc aaacaaaaca
     9481 aaaagcatgg gaccacctgc cataaccaca ttaaagagac cacctatgac tgagaaacga
     9541 aggaccaatc gattaataaa tagactagta tccgcacctg gataaatacc ataaatgtat
     9601 tctccagatt ttttcatacg gtctgcaatc tcttctccat tcatcgtaac aaaagcaaaa
     9661 atgatactaa ataaaaataa gaccgaaata taaacataga cccacaaagg ctttccaatc
     9721 ataaattcct ttgataaagc cgctaaccct gaatgattag ggaaaataaa tcccaacaag
     9781 atgaacaaat aagctggtac actaagaaaa ctcatcacat acatataagg catcccacct
     9841 gcaggattca acatgatttc gagataagaa tagcgtttaa atcgattgtg taagccaatt
     9901 ttattaacag gaaccaaata gcgagctcga tacataaggg caagtaaata agaaaagaca
     9961 agggttaata aagcaagtaa cacaataatc cctgttggaa tgtgtactgt ctgaaatgtt
    10021 tccaaaacat cctgaggaat atttaaaacc atactggata ggaggagtac aatagaacct
    10081 ccaatcccca tactcgcatt taaatctgac aaccaaacaa gaaaaaatgt tcctgctatc
    10141 agcaacaagg tattcattag aacaaccaaa attaccgagt aggaggattg tactggcaag
    10201 ctcaagctaa ctgccaagga ttgaatcaca gcaattagca aggtcagata catttttcga
    10261 cgatcttgaa tttcaatcgc tgtagaactt agccccaatt ttttagaata tgaaaacatc
    10321 tgccacaaaa tcatagctga catccaaggg gataatccaa cagaaaaaat tgacaaactt
    10381 cttagatttc cacctgttag ggcggctgag aaggctagat aggctgttga acctcctaaa
    10441 aaatctttag tatttaggtc aacaaaaggg agaataatac gacttcccaa tacatagata
    10501 aacagtagaa ataaggtaaa tagtcctttt tttactgcta ttgacgaata aatcttagtc
    10561 ataaaacact cccctcacct tcattgtttg tgatatggta aataacaatt cttttatttc
    10621 aacttttacc atttctttgt tctgcatcaa aaaacaactt taatctgaaa caaatatctt
    10681 tatattcctc agtatctgtt aattgatgat attctaaagt ttgcttataa tcttttaaaa
    10741 gattgacaaa tcgaatacgc agaacggaga tatccaaacc agccaagaca caatccgata
    10801 ttttcttaga aaacacttca acaatatatc ttgcccagga aagatcaaat tccgttctca
    10861 tgatgcttcc tgaacgtctt ctatacagat agagattatc gtttataaag acgattttag
    10921 aggctaaaag ataaaagcga tgcatagttg cttcatcatc aaagcggcga ccatttgaaa
    10981 agtgaacttc attgaataat tcttttttaa tcaacttaaa tgtcggcaat ataaaggccg
    11041 agctattgaa tttccaatct cctgcttgac ggttcataat ttcttgtata gctaattctt
    11101 cgacgcaaaa atcttgccct gttacataaa aataaaaatt cccgtcactt tcgtcataat
    11161 tatagtaatt ccctataaca acatctgcat ccttttcttg gacttgctga taaagagttt
    11221 caatcatatt ttcttttacg atatcatctg aatcaacaat cgtgatgtac tctcccttag
    11281 ctacactaat ccccatattt ttagcttgtg ctgccccccc ttattttctt gatgcaatac
    11341 tcgcacacga ttatcttgca tcataaaagc atcacaaatt tccccagaat tatccgtaga
    11401 agcgtcatca actaaaataa tttctatatt ttgataggtt tgcttcagaa tatgctcgac
    11461 acactccact aaatattttc ccgtattgta tatcggtacc acaacactaa ttaattcact
    11521 cattactcta tctctatatt cttcattcta tccactaaat catctggtct ctccacagaa
    11581 aaaataccgt catagagtcc atcatccata cttttacgtg tgatatcaaa agcgaagatt
    11641 ttcttgccac tttcttgtgc ccttgtaact acattaaaaa cctctccacc tgtattaata
    11701 tctaaataaa ctatagaatc gtccaatagc caatcaattc tactatgtaa tacattttga
    11761 tatactgtta cattcgtata ctgtgataga gaggtcagct cctcagaaca atcacacggt
    11821 gcagccaaat gaaaatgcca atcaggtaac cgttgtacta aatactctaa atgttttata
    11881 tctgcactcc atgtcacaag catcacttgt tttttagact gattgcttct ttcaaaataa
    11941 tttaaatcgg aacgttgaaa agcaatctct gaccaatcca aatctctata aacccaccat
    12001 aattcacgta gtctagatat actatatgta ttccaaggtt tatcatgact agcatagtga
    12061 acaattgtag gtggattgtc atctagacgt tcacattctt gagcaaggtg ataaatatca
    12121 acacccacca tataattata tgttttatct aaggctagcc aattatcctc aaaataaata
    12181 tttaaaatac tctgatcccc aagatgaaca acttgattct gctcggccgc taattccaat
    12241 aaactattga caatagaatg ttctttccac tttgcaacat ccattagtaa cataccagca
    12301 ttaaatccag attttcgtcc ttcataggca tagacatcat caacagcacc aattgaatat
    12361 cctttgagat ctatctcaaa caaagtagct agttccccag ttacaatgat atcggaatcc
    12421 agatacaata ccctatcaga ttcaaccact tctgtcgcaa aaaatctaaa gtaagaagca
    12481 taatttatat gaggtcctgt tttatagctt tcaaaaagtt ctttatcaat gtgtacactg
    12541 cgaattgtag aatgcacaac ttccattttt ctccccaata atttaaacca ttcaggagct
    12601 atatcactgt tgagaatata aaaatcaaca tctctattgt gatacaatac agactttata
    12661 gtcgtctcta aaggaataag ataggcatta tctgccgcta atactattga ttttctcata
    12721 ctgttctcta cctcatgtaa gatctgattg ctgcaaccat ttttttcgga atggagcttg
    12781 gatagatacc ttcatatgaa atctcagaaa gattttcaga gcaagtattg tcgaaagcta
    12841 tcattggttt tttgtactta agcacaaact catatgcatc ttctaatttt cgatcatgat
    12901 tcaaatccaa atacaaatct gaagctatta ctatttgttc caataacatt ggtaaggaat
    12961 ttggatatac ggtaacatta ggaaaacgcg ttaaagctag tagttcattt gccatatttg
    13021 tataagcaac aatatgaaaa tgaacttctg gcaattgctc cgccaaataa tcgattttct
    13081 cgacacacca agaattcgtt aaattaacac attgtaactt aaatatttgt gatttactag
    13141 gatacttcac actctttgaa aaccattcat ttaaaataac agaccaatcc atcaaagagt
    13201 attcccacca aacttctctt agacgtccaa cagaaaattg attccaaggc ttatcctgag
    13261 aaatatagtg taaaattagt ggcagtggtt cgagcggaat atcaaaaatg aattgatgtt
    13321 taaaggctgc cgccccataa tcatatccta tttgaaaatt atattgatct tcaagggaac
    13381 tatattgatc tttaaacaac atattcaaaa ttgactggtc tccttcttcc acattctcat
    13441 gttctttttc tgttaagtca atcaattttt gtcgaatagt ttcagatccc cattttttgt
    13501 tgttaatcaa gagaacacca gcattgaagc cgactcctgc tccaaagcaa gaacgagctg
    13561 ctgccaaata attttcacct aagtctaatt caaacaaatc ggtcaaatca ccagtcacaa
    13621 tcaaatcact atctagatag agaactttat cttctgttac aaaatctgga ataaaatagc
    13681 gtgcaaatgt catatgattg atatgaggta atttattaga ccaattcatt tgaaactgtg
    13741 agccaattaa cttgcagtca atcaagtcgc cccccatctc ttgtaaatat attcttattt
    13801 gactaaacca ttcctgagga atgtcctgat ttagcagata aattttcaaa tgactattgt
    13861 gtctacagag tgacttcatc gccgtttcga tttgtcgaat ataagcgtaa tcacctgcaa
    13921 atactacagc gcgtttggta tttctcattt taaatcctta tcatttattt taaatagtct
    13981 agtttaatat tcgtgcaaca atctgactgt tataggtttc atcatcaata aattcaatat
    14041 cttggtcgaa attatgttct gcagtatgtt tatgagaaaa tttaacctta gttttagctc
    14101 ccattttcat ccattcatac tctgagtcaa catggcctac atccaaaact tgatagccca
    14161 tctggcatag attataactc agaacttttg ctgtaggacc cagcatacat aaaatcagtc
    14221 ttccttcagc atgtttcata atttcctctt gaatgttatc gacaacggaa taagcattat
    14281 gagatggaca aataatcctt ttcacagatt tgaccttatc aaataaatca tttccaaccc
    14341 cagagcgaga tgtaatcccc tctacaatca gaatatccct attctcccaa atactcttta
    14401 gcttttcaaa ttgtcctttt gccttactct tatcttcata atcaatgtat ggacgcgaga
    14461 taaaggtaga gccataccat gaacccttac acaactcttt ataaaaatcc atataaacat
    14521 tcatatgttc tttccagaat ggtgtagccc accaagtaaa gacaaaacga tcgtcaaaag
    14581 catcaggtaa acaaaccact aatttctcgt cactctcaag acccacaata tgttttaatt
    14641 ggttagctaa ctctagatca tgattttgat aaggtatagg caaaccccac atcaaattga
    14701 cttctccgtc tccaaaacga actaatgagg acttattttt gataacataa tccagagtct
    14761 gatcaattcc gataaccttg attggcttct ctggttctcc caaagtctct ccttttatca
    14821 atgcatgaaa tgcttgaaga agcctttctg gatgctcact tgaatataaa tgttgaccat
    14881 gatttccatt ttgtgaagta taaaatgcca gcattggttt attcaatgat gatatctcct
    14941 tgacaacctc actagtagaa ttgtgtaggt taatatccaa ataaacatcc atttgagatt
    15001 tgagtttttc aaattgatcg attttcactt caggatatag cttaacattt ttatattttt
    15061 ttgctagttc ttgtaacatt ggtcccataa ctgtccaagc agcaacttga aaaacaacat
    15121 ttggcaactg tccagccaag taatccaatt gttcgatatc ctgagaagcc gtaaacgtta
    15181 aacaagttaa acttggaagt tgtcgaaaac aggtaagatg tccgtttttc ttaaaatctt
    15241 taatcgtatc aatcataaag gaaactttcc cattttcgaa aacgatttgt cctaactctc
    15301 cgtgctgagt cgattgaaaa gctagtagcg ttttttcttg ttcttgcaaa gattttaaaa
    15361 agttctcatc tgcactacca tgattgatat ccaaatatag atttgttgac tttttcagct
    15421 tatctaatac aggaggaaca atttgtggat gcaatctcac attattatat acagctaatt
    15481 tttttaattt atctcccata tccgtccaag ctgcgatatg aaataccacc tcaggtagag
    15541 ctgtaactag ctcttctatt ccttctaaat cttgggaatt cgttaaggtt aagcaagaaa
    15601 attccttatc tagaggcgat attagttcaa attctcccat atggtgttgt aaaatctgac
    15661 tccactccaa atcatggaat tcccaccata aatcacgata acgattggct gtcaaggtag
    15721 tccagggttt tctgtaggtc gtaaaatgaa tcaccactgg tttatcatta aaagccagat
    15781 gttcctgcca attgttatac aaagccacaa tatcatgccc tacttgtaaa ttataagctc
    15841 gacctagctc taaccaatca tcttgtaaga cctgattaaa aatcgtttga tcaccattaa
    15901 aatgctcgaa acggccttct tcaacttcct tcattgtaac aatgctctgt tcaattagtc
    15961 gttcttttaa tttctcttga cgccattttt tattgttgat taataaaaca cctgtattaa
    16021 atgtaattcc atctgtatct ttaactgctg cgagtgattt ttcttctaaa taaatactaa
    16081 ataatttctc taaagaagta tttacaatca aatcactgtc taaatataaa accttatctt
    16141 cttggatata atctgcaata aaatatctag cataggtaat gctactaatg tgatcttgct
    16201 tttcccaatc ttgaaacaca gtttgttcag gtagcttcac atcgataatc tcactaccta
    16261 acatgcgagc tatttttcgt ggctttcgaa accaatctgg catgatatct tgatttaaaa
    16321 tataaatctt aacatctcga ttgtggtata gaatagattt tatggttgtt tctaactgcc
    16381 tggtgtaatt acgatcacca gctaatacaa ttgttttgtt catttcactc ccttaatcaa
    16441 ttcccaagtg ataaatcgca tctaccaata gctttttagt gaaatagccc tcttttaaca
    16501 aatagctaaa ggtcttgata cgattcgtca tttcttgata ttcttgtaga ttcattttat
    16561 caactatcgc atgtacttcc tcaaggctat ccgccataaa acctaagccc tgatctacta
    16621 taaatttagc agttgataag ttgctcggta caatgactgg gatgcccgct gttagatagg
    16681 tactaacctt atgagatata tttaaagtat agtattgatt gctttctccg tcattttgat
    16741 gcgttcccca gacaagacca aagccacctt ttgataattc tagcaacagt tcctcatctt
    16801 ttttccatcc ttcaatgcta agatttctag cattggaact agcttctcct ttatttgaaa
    16861 acaccctcaa aggcgtatct tgagaccaat tttgtaagtc tggaaaacgc tctaaacttc
    16921 cagcaaaaaa aagttctttt ttaaaagcag gggtgtataa ggataaatca tgaggatgat
    16981 cccacatccc ttgaacaaga atcttcttag tcgtcaatcc ttcttccatc aggcgtgttt
    17041 tcattctctc tgacggcact atcaaaacat ctgatagatt atacatgtac atataatctt
    17101 tcatgagata atagttacta tcaaacatga ggggaacaac atcatggata aagcaaataa
    17161 ttttcacctg catatccttt agcttatcaa acaagagacg atcaaattca aagccattcc
    17221 aggttggaga ctgaaaaact aggatatctc caatagagat actggccata atgccatcca
    17281 gacgcttatt catttcagaa ggactatctg aagaaatatt gtaaaaatag atgccaacct
    17341 ctctaaatcc cagttgactg gctatctttt gaacagcatt ttgcgctaag ataaccgtac
    17401 tatcaccagc catgccgtat aaatttgtta aatgtagttt catattatgc tatctcattt
    17461 tttattacta tctacggaag taaagacaat ttttccatca ttcttctata aatttctgtg
    17521 aactgcatat tttgttcttc taattttgct actactcttt gtaatctatt tttataaatc
    17581 aaaatatgat tggtcaagtc atagtctgaa cttgctaaaa tagctatctt ttcttcccta
    17641 gccccaattt catcatacat acgcttttca ctccatgtat tcgataaagt atcagataaa
    17701 ccaacacggt accagtaaac acaacgattc aaatagacta tcctcgaagc tcttagaagt
    17761 accttccatg tccagtaagt atcctctgca atttttccta taggaaatgg taaatcttgt
    17821 agtaactctc tcttgaataa cttcaagaca gctacagtcc agttcccatt tctgacttct
    17881 tcgacacctt ccctatccat gattgcttta ccttctatca cttccagaga atcatctgga
    17941 tccgtaacat aagtcatata cacatagcgt gtttcatcat aagaattata acgcccgata
    18001 ctaatatctg cgttttcctt tttcaaagca ccatataatc ggtctaaagc atcatgttcc
    18061 aaccaatcat cagagtctac aaaagtaatg tacgcccccc ccgaacattc aatacctagg
    18121 ttacgagctg atgaaagacc gccgtttgct ttctcaaaat atttgaaacg agaatctttc
    18181 tctacaaatt cttcacatat tttggatgaa tgatctggag agccatcatt gattaataaa
    18241 cactcaaaat tttgatacgt ctgattctga atgctatcca aacacattcg caaataattc
    18301 tcaacgttgt agattgggac tacaatacta attagttcat tttccatata ctaactttcc
    18361 tagacttgat ttattctatt tccctcttaa tctcttctct ttacaaaaag atttccatta
    18421 ttataaacta cactgtttga tggaatatca ttgcgtatga gacaacctgc tccaataatg
    18481 gtattatccc caatcgtcac tccttttaaa atcgtgacat tacttcctat ccagcagtct
    18541 ctgccaactc taatcggcgc tgtagtccac tgccactttt caatcttttc agcagtataa
    18601 atatggtcgt gatcataaaa acgaacaccc tctcccatca tggtaccagc tccgatttca
    18661 attctttcca tacagttaaa actacaagag ttgttgataa aaacaccatc attcaggatt
    18721 aacttaccag aagagacatg aaaattttca aaatttctgc agatgacatt tgctcctaca
    18781 atgaagtgag ccttatcatc gattttaaag acattccaag tcccatcttg gatgattttc
    18841 tcttgatgat tggtgcctac tctgacttca ttcagatagt ctctcactct agaaaacaat
    18901 ttgtctggtg tacttgatag aaaaacttcc tgcccctgat ttccatggac tgtattgtca
    18961 aaagcaaaga cagattttcc agcctgtaca aacttggaga caatagcatc tacttcttga
    19021 aagtgattga tatctagtaa aaagtcacag gtatcgacta gaaagtttag ctgttcttca
    19081 tttgtaatcg ttcggagacg gacattatag ttcgtttcta agctacggat tttctcggaa
    19141 aattgaacag gtgctgcaat ataaaaacag atatttggca aggattcaag gagataatcc
    19201 aactcttcaa tctgatcact aacagtcaaa atcagagcat ctcctactaa atgatttttc
    19261 ttcatttgct tatttctctc aatttctcaa tcattgcttg aacttggtca acagcatata
    19321 cctcctgacc tgcttcatag gttttggtat tttcaaagga caaaatagtt tttccaagtc
    19381 ttgcaaattg attgataatt tcctctgttt tttcaccatg attaatatct aaaagtactt
    19441 gactggtttc taccaattca ttatcgacat ctaccaaata gtgaattccg ttaaatatag
    19501 tcacgtttgg ataaattgtc atctgagcca atcgatcact aactattact ctagctgcta
    19561 tcttaaactg aatatcaggc aaggattgaa ccaatgtctc aatttgttca atatggtctg
    19621 aggcagtata gattagacaa gtgaaaggtt cctttattgg atagatgtga gatctttgta
    19681 atggatgtaa atgatggttt tgtcccaatt ctgtccattc aagcccatga tagtaccacc
    19741 aaacttcacg ataggtttgg gccgccaaat ctttccacgg tttccgatga gaaagatagt
    19801 gaataatagc aggataatcc tgaccctcag gcaattgata atcagcaaac tgtttatgaa
    19861 tgacaatatg attataatca aagtccaatt ccaaccattt atgttcaaaa agcatattca
    19921 agatgctctg atctgcctga tccaccttat catgccattc attggttaaa tcaattaatt
    19981 tttgggtcat attctctttt ttccaaaaag cattgtttac caagagaaca ccggcattaa
    20041 agatttcttg accaaaataa gctctgcccc caaaatctct aacagcagcc aaaggataat
    20101 cttgtaagtc tgtagcaaac aagtcatcca gatttttcgt tacaactaga tcacagtcca
    20161 agtagagggc cttgtcttct tgcacgaaat cagctatgaa atagcgtaaa aagactgtgt
    20221 aactaatatc cgatttataa catgaaattt gctcagaagt tacccgacaa ttaataattt
    20281 ctgagtcaca cttctctaag cgcttattta attgcttaat ccattcattt ggaaaatcgc
    20341 tatgaatcag ataaaaacga atcgaacgat tatgataaca aatagacttg attgtcgtta
    20401 aaacttggtc tacataggca taattcgccg ctaggacaat ggctttcttt tcacttgatt
    20461 cttgtaccgt taactgattt aaaagtcttt ttttcatttc aaactcttta tacattgctg
    20521 tgtcagataa accgctagct tgaccgttgg cgagactgac ttccaacatc tgacgataaa
    20581 ctgccaagtg tttctctaga ggataaccca tattagctag tagcgtaata cgttcagaca
    20641 tagcatcaac taaggcgtgc atccactttt ctgtccaaac tcttgataaa ctaccttttc
    20701 taatccgata agcataaaga cctttattta aataaattac cttttccgat aataaatata
    20761 ccttttgatt gagtaaccat cttctcctaa tttacccatg tcaaagcgca actgctcaaa
    20821 caatcttgcc ttatagagtt taccacaagc agatatcaaa gcaaaactct tcatttcttg
    20881 agtttcatac aagttctcaa agatggaaac attgtcatat accttctcat aataggagtc
    20941 tcctgatata tgaaagtaga acattccttc actttcgttg aaagaatagt aattcccaac
    21001 tgcaatatca gcttgatatt ctgttatttt tttatatagg gtttctacat aatctaactc
    21061 aatccaatca tctgaatcca caaaggtcac ataatttccg gacatattat tcagaccggt
    21121 gtttcgtgca gctgacagcc cagcattttc ttgttctata taggtaattc ggtgatccat
    21181 ttctgcaaat tctttacaaa tttcacctga agcatccgta gaaccatcat taacgacaac
    21241 aatctcaata tttttatatg tttgagtaat aatactatct agacatttcc tcagatagtt
    21301 ttctacattg tatactggta caatgaccgt aattttatca tccactagca attttctcct
    21361 tgatttatgt gcgcgagtta gtttagccta actttacagg ttgtcttact cttcttcatc
    21421 acgtttacgg cgtttcgcaa ccaatccaat acctgtaaca gctgctagaa ctccaagtaa
    21481 cacagatcca attgacgact cagtacctgt attaggcaat tctttttggg atttacctgt
    21541 cgatccagaa gcatttccaa cttgtgagtt cgaatggttt gctgaatttg aaactgatgt
    21601 acttgctgaa gctgacgcac tggttgatgc tgaggctgag gcgctagtac ttgctgaagc
    21661 cgaggcactt gttgatgctg aggctgaggc gctagtactt gctgaagctg atgcacttgt
    21721 cgatgctgag gccgaagcac tggtacttgc tgaagccgaa gcactcgttg aggctgaggc
    21781 tgaagcactg gttgacgctg aagctgaggc actcgttgag gctgaagccg aagcactcgt
    21841 tgatgcggaa gctgatgcac ttgttgatgc cgattcagac gctgagatac ttgctgaggc
    21901 tgaggcgctt gtacttgctg aagtcgacgc actggttgag gccgattcag atgctgacgt
    21961 acttgcactt gttgacgccg atgtgcttgc acttgtcgat gctgacgcac tcgttgatgc
    22021 ggaagctgag gcgctcgttg atgcggatgc tgacgcactg gtgcttgctg aagctgatgc
    22081 actcgttgat gcggatgctg acgcactggt tgatgcagat tcagacgctg agatacttgc
    22141 tgaggctgag gcacttgttg aggccgattc agacgcactc gttgatgcgg aagctgacgc
    22201 actggttgac gctgaggctg acgcactcgt tgatgcggaa gccgaggcac tggtgcttgc
    22261 tgattcagat gcacttgtcg acgctgaagc cgaggcactt gtcgacgctg aggctgaggc
    22321 actggttgat gctgaagctg acgcacttgt tgatgctgaa gctgaagcac ttgttgacgc
    22381 tgaggctgaa gcacttgttg aggctgaagc tgaggcactg gtgcttgctg aagctgatgc
    22441 actagtactt gctgaagctg atgcactggt tgatgctgag gctgaagcac ttgtacttgc
    22501 tgaggctgag gcgcttgttg atgcggatgc tgacgcacta gtgcttgcgg aagccgaggc
    22561 actggtactt gctgaggctg aagcacttgt tgatgctgaa gctgaggcgc tagtacttgc
    22621 tgaagccgag gcgctggtgc ttgttgaagc cgaagcactg gtgcttgctg aagctgaagc
    22681 gcttgtcgat gctgaggctg aagcactggt tgaggccgat tcagacgctg aggtacttgc
    22741 tacagatgac ttggaaactt ctgtacctgt atttggcaat tgctgtcttg acttacctgc
    22801 tgaagccgag gcgcttgttg atgctgaagc cgacgcac
//
LOCUS       DAVEHY010000035        22830 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVEHY010000035 DAVEHY010000000
VERSION     DAVEHY010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.035"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..393
                     /locus_tag="VUZ44_001647"
     CDS             <1..393
                     /locus_tag="VUZ44_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU0320522.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKESK"
     gene            815..1195
                     /locus_tag="VUZ44_001648"
     CDS             815..1195
                     /locus_tag="VUZ44_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU0320523.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            1654..2367
                     /locus_tag="VUZ44_001649"
     CDS             1654..2367
                     /locus_tag="VUZ44_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU0320524.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLTQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2425..3027
                     /locus_tag="VUZ44_001650"
     CDS             2425..3027
                     /locus_tag="VUZ44_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320525.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCIGDFPHDFF
                     DTYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3163..3816
                     /locus_tag="VUZ44_001651"
     CDS             3163..3816
                     /locus_tag="VUZ44_001651"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU0320526.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3826..4290
                     /locus_tag="VUZ44_001652"
     CDS             3826..4290
                     /locus_tag="VUZ44_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU0320527.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4303..5571
                     /locus_tag="VUZ44_001653"
     CDS             4303..5571
                     /locus_tag="VUZ44_001653"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU0320528.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5585..5845
                     /locus_tag="VUZ44_001654"
     CDS             5585..5845
                     /locus_tag="VUZ44_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320529.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5856..7217
                     /gene="pdrM"
                     /locus_tag="VUZ44_001655"
     CDS             5856..7217
                     /gene="pdrM"
                     /locus_tag="VUZ44_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU0320530.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7371..8339
                     /locus_tag="VUZ44_001656"
     CDS             7371..8339
                     /locus_tag="VUZ44_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU0320531.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8355..9347
                     /locus_tag="VUZ44_001657"
     CDS             8355..9347
                     /locus_tag="VUZ44_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU0320532.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9565..10608
                     /locus_tag="VUZ44_001658"
     CDS             9565..10608
                     /locus_tag="VUZ44_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU0320533.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLATSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10672..12357
                     /gene="lpdA"
                     /locus_tag="VUZ44_001659"
     CDS             10672..12357
                     /gene="lpdA"
                     /locus_tag="VUZ44_001659"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU0320534.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12421..13410
                     /locus_tag="VUZ44_001660"
     CDS             12421..13410
                     /locus_tag="VUZ44_001660"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU0320535.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13483..14553)
                     /gene="xerS"
                     /locus_tag="VUZ44_001661"
     CDS             complement(13483..14553)
                     /gene="xerS"
                     /locus_tag="VUZ44_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU0320536.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGCKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(15137..16687)
                     /locus_tag="VUZ44_001662"
     CDS             complement(15137..16687)
                     /locus_tag="VUZ44_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU0320537.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16703..17482)
                     /locus_tag="VUZ44_001663"
     CDS             complement(16703..17482)
                     /locus_tag="VUZ44_001663"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU0320538.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILSKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELLKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17469..18320)
                     /gene="ylqF"
                     /locus_tag="VUZ44_001664"
     CDS             complement(17469..18320)
                     /gene="ylqF"
                     /locus_tag="VUZ44_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU0320539.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18539..18715)
                     /locus_tag="VUZ44_001665"
     CDS             complement(18539..18715)
                     /locus_tag="VUZ44_001665"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU0320540.1"
                     /translation="MQAGIPTDNEVSYDLIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18767..>22830)
                     /locus_tag="VUZ44_001666"
     CDS             complement(18767..>22830)
                     /locus_tag="VUZ44_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEU0320541.1"
                     /translation="PEKNGTATKPENSGNTTSENGQTEPEPSNGNSTEDVSTESNTSN
                     SNGNEEIKQENELDPDKKVEEPEKTLELRNVSDLELYSLSNGTYKQHISLEQVPSNPN
                     SYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEIESRYKDNFTFYLA
                     KKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVELSTDDKSYIKGTFTGQLI
                     GEKDGKHYAIYNLKKPLFESLRGATIEKLSLKNVSISGKDDIGSLANEAQNNTKIKQV
                     HVDGVLAGERGIGGLLAKADQSSITESSFKGRIVNTYETTAAYNIGGMVGHLTGDKAL
                     LTKSKATVAISSNTNTSDQTVGGLAGLVDRDAQIQDSYAEGDINNVKHFGRVAGVAGN
                     LWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYNEMKVKDTFSSKDNRVYNVTLVK
                     DEVVSKESFEERGTMLDASQIASKKAEINPLILPTVEPLSTSGKKDSDFSKVAYYQAK
                     RNLTYKNIEKLLPFYNKATIVKYGNLVNENSLLYQKELLSAVVMKDNQVITDIVSNKQ
                     TANKLLLHYKDDLSEKLDLKYQNDFAKLAEYSLGNTGLLYTPNQFLYDQTSIIKQVLL
                     DLQKVDYHSEAIRKTLGISPNVKQTELYLEDQFAKTKQQLEDSLKKLLSADAGLASAN
                     PVTEGYLVDKIKRNKEALLLGLTYLERWYNFSYGQVNVKDLVLYHLDFFGKGNASPLD
                     TLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKVFLPNTSNNDWFKS
                     ETKAYIVEEKSTIEEVKTKQGLASTKYSIGVYDRITSATWKYRNMVLPLLTLPERSVF
                     VISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHYDYWYRILDDNAR
                     EKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVGNKVGHNQHGAYAT
                     GDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDH
                     PDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLKQYVHNMFDVVYMLEYLE
                     GNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNLTVEEVERLRSFNDLIDN
                     NILSSREYASGKYERNGYFTIKLFAPIYAALSNDIGTPGDLMGRRIAYELLAAKGFKD
                     GMVPYISNQYEEEAKQKGKTINLYGKTRGLVTDDLVLEKVFNNQYHTWSEFKKAMYQE
                     RQDQFDRLNKVTFNDTTQPWQTFAKKTTSSVDELQKLMDVAVRKDAEHNYYHWNNYNP
                     DIDSEVHKLKRAIFKAYLDQTNDFRSSIFENKK"
BASE COUNT         6783 a         4304 c         4702 g         7041 t
ORIGIN      
        1 gaccatgttc aaagaaacaa aaatggtcaa gctgatacca atcaaacgga aaaaccaagc
       61 gaggagaaac ctcagacaga aaaacctgag gaagaaaccc ctcgagaaga gaaaccgcaa
      121 agcgagaaac cagagtctcc aaaaccaaca gaggaaccag aagaagaatc accagaggaa
      181 tcagaagaac ctcaggtcga gactgaaaag gttgaagaaa aactgagaga ggctgaagat
      241 ttacttggaa aaatccagga tccaattatc aagtccaatg ccaaagagac tctcacagga
      301 ttaaaaaata atttactatt tggcacccag gacaacaata ctattatggc agaagctgaa
      361 aaactattgg ctttattaaa ggagagtaag taaaggtagc agcattttct aactcctaaa
      421 aacaggatag gagaacggga aaacgaaaaa tgagagcaga atgtgagttc tagttctcat
      481 ttttttcatg aaaatgtgca aaatatagta gattgaaact agaatagtat acctctactt
      541 ctaaaacatt gttagaaatc gatttgactg tcctgttctt atttcatttt actatatctt
      601 aacagatagt gtaaataaag ataaactatt tactggctaa ttgatcagtt aaacactagt
      661 taaggagtaa tgatgaaaaa aagaacaata ctattattaa tggccagtct gttagctctt
      721 gtcttaggag catgtggttt cttggacata ttgatcctgg atcattctca tcaggattac
      781 tctttactgc tattttagaa actggggtgg tttgatggaa agtattggta ttggtcttgt
      841 tatcgtttca cattccaaac acattgcaga aggtgttgtt gaactgatta gtaaagtagc
      901 taaagatgtt ccgattactt atgtaggagg aaccgagggc ggaggaattg gaacgagttt
      961 tgatcaagta gatagggttg tttccgaaaa tccagcagat actttacttg ccttttttga
     1021 cctaggttct gctaaaatga acttaaaaat ggtgactgat ttcagtgata aaagtatcat
     1081 catcaacagg gttccaattg tagaaggtgc ctataatgca gctgctcttc ttcaggctgg
     1141 tgcagaactg tcagttattc aaacacagtt agcggagctt gaaatcaata aataaggaat
     1201 tttactataa ctctttttat aggtaagcta ttgattatct caactataaa atgttaagta
     1261 aatgatttca aaatcagaaa gggattgctt tatgcagttc ctttttattt taacaggagt
     1321 gaaactatag tgtttctaaa ttgtgaatca atcaaaactg attgtgatgg gactattcta
     1381 gctttagaat ccttcaaaaa ttaaaattta agacaatcaa ttacttggaa gagtatgaaa
     1441 gcatttagtt tataggaatt ctaggtctag aattacacat atatttatga agacggggtg
     1501 ctcgatagtt agtattgttc tattctgaaa gatttgagct gtcagttgta tagaaagtgt
     1561 tcgaattttt tttaagtgat taaattagtt aattgtatga ggtgctttat gatataatgt
     1621 tcttaatgaa ttttcagaaa ggaaaatctc aaattgttct acaaatttct actcttcgac
     1681 ctcgaccaca ctcttcttga ttttgatgct gctgaggatg tggctttgac ccaacttcta
     1741 aaagaagaag gagttgcgga tattcaggct tataaagatt attacgttcc tatgaacaag
     1801 gctctctgga aagacttgga gctgaagaaa atcagtaaac aagagctggt taacacgcga
     1861 ttttctcgtt tatttgctca ttttggacag gaaaaagacg gtagttttct tgcccagcgt
     1921 taccaatttt acctcgccca gcagggacaa acactatcgg gcgctcatga tctcttggac
     1981 agcctcattg agcgtgatta taacttgtat gctgcgacaa atggcattac tgccattcag
     2041 acaggacgtt tgactcaatc tggtctagca ccttatttca atcaagtctt tatctcagaa
     2101 cagttgcaaa ctcaaaagcc ggatgctctt ttttatgaaa agattggcca gcaaattgct
     2161 ggatttagta aagaaaagac gctgatgatt ggagattctc taaccgccga cattcaaggt
     2221 ggcaataatg cggggattga cactatctgg tataatcctc atcacctcga aaatcacaca
     2281 caagcccagc cgacttacga agtctattct taccaagact tgctggattg tttagataaa
     2341 aatattcttg aaaagatcac attttaaagg agacgagcta atgactacaa aaaagctaat
     2401 attactattg aagagtacat tgaaatgtct gaagttgatt ttaatgaagc tgttaattat
     2461 gaatttacat ctgacacttg tcaattagca aatagtattt atcaatctct ttttaagttt
     2521 tttgataaga aaaatttctc tggcgattta atttttactt ggaaatctcc atcattagtc
     2581 aaagaagggg attatattgg gagaagggat tcacaagtag ataatcttag agtaatagga
     2641 aatatatttc cgaattatct tactaatcga aaatatagcc tcaatatgaa tcgtaatggc
     2701 tgtataggag attttcctca tgactttttt gatacatacc tagatcatgt agcaaaatat
     2761 gcctacgaac aaaaagttaa taatattaaa gagtattatc ctttaaaaag agcgatttta
     2821 caccaagaga atgcattgta ttttcgattt ttttctaatt ttgacgactt tttagaaaaa
     2881 aattatttaa agactatatg gcaagtttct aaagaaactc ctttttctga aatggatttt
     2941 aatatgttta aaaatatttc agaaaagata atcttcgaaa gaggtagtaa aatgcttaat
     3001 gatttaaaaa gtaattataa aaaatagcca gtctttataa actgtattca cgtattcaaa
     3061 tcgtatatag tcgatttatt aaatctttag ataaattgta aaaagtggtt tccatagcca
     3121 ctttttgcta taatagaggc agtaaaaatg aaggagtcag ctatggaaca ctcgtcttgg
     3181 catgctttga ttaaggcgca attacctgag ggttatttcg ggaaaatcaa tcagtttatg
     3241 gagcaggtct attctcaggg gattatttat ccacccaagg aaaaggtttt tcaggctctc
     3301 ttgacaacac tgcttgaaga agttaaggtg gtaattctag ggcaagaccc ctatcacgga
     3361 ccaggtcaag cgcagggctt gagtttttct gtacctgact ctatcccagc tccaccatcc
     3421 ttgcaaaata tcttgaaaga attgtcagat gatatcggag ttaagaaatc tcatgatttg
     3481 acagcttggg ctgagcaagg agtcttgctt cttaatgctt gtttgactgt tcctgctgga
     3541 caggccaatg gtcatgctgg tcaaatctgg gagcctttta ctgatgctgt gattcaggtg
     3601 gtcaatcatc tagatagacc agtcgttttt gtactctggg gagcttatgc acgtaagaag
     3661 aaggccttag ttaccaatcc tcatcacttg attatcgaat cagcccatcc aagtcctttg
     3721 tcggtttata gaggattttg gggttccaag cccttttcca aggccaatgc attcttaaaa
     3781 gagacaggac aagagccaat cgattggctt agataaggag aaaatatgcc tcagttagcg
     3841 acgatttgct acattgataa tgggaaagaa ctgctcatgc tccatcgtaa taagaaaccc
     3901 aatgatgtcc atgaagggaa atggattggt gtgggtggta agctagagag aggagagacg
     3961 ccccaggaat gcgcggcgcg tgaaatcctt gaagaaacag ggctcaaagc caagccagtt
     4021 ctaaaaggtg tcatcacttt tcctgaattt acaccagatt tagactggta cacctatgtt
     4081 tttaaggtga cggagtttga gggcgacttg attgactgca atgaggggac gctagaatgg
     4141 gttccctatg atgaggtttt gagcaagccg acttgggaag gtgaccacac ctttgttgag
     4201 tggcttttag aggataaacc cttcttttca gccaagtttg tttatgatgg ggataaattg
     4261 ttggataccc aagttgattt ctatgaataa aggagaaagc agatgctact aatcaaaaat
     4321 ggtcgtgtaa tggatcccaa gtctggtttg gatcaagttt gtgatgtctt agttcaagat
     4381 gggaaaatta tcaaaattgc gtctgagatc acggaagaag gagcagaaac gattgatgct
     4441 actggtcttg tggttgctcc tggcttggtc gatattcatg ttcatttccg tgaacctggt
     4501 caaacacata aagaagacat tcatactggt gccctagcag ccgctgcagg tggttttact
     4561 actgtcgtca tgatggctaa taccagtcca accatttcag acgtggagac tttgcaagca
     4621 gttctccagt cagctgccaa agagaagatt aatgtcaaga cagttgcgac cattactaaa
     4681 aactttaatg gtaaaaactt gactgacttt aaggcactct tagaagctgg tgcggttggt
     4741 ttctctgatg acggtattcc gcttgagagc agtaagattg tcaaggaagc catggaggaa
     4801 gccaaaaaac tcaatacctt tatcagcctt catgaggaag atccaggttt gaacggtgtt
     4861 cttggcttta atgaaaatat tgctagagaa catttccata tctgcggtgc tactggggtg
     4921 gctgagtacg ctatgatggc gcgtgatgtc atgattgcct atgcaactaa agcccatgtt
     4981 cacatccagc atttgtctaa ggaagaaagt gttaaagtag tggagtttgc tcaggggtta
     5041 ggtgcagaag tcacagcaga agtagcgcca cagcatttct ctaagacaga agcacttctt
     5101 ttaacacaag gtagcaatgc taagatgaat ccaccgcttc gtttggaatc agaccgtcgt
     5161 gccgttatcg aaggtctcaa atcaggtgtc atcacagtta ttgcgactga ccacgcgcct
     5221 catcatgtag atgaaaaaaa tgttgaggat attaccaaag cgccatctgg tatgactggc
     5281 ttagaaacat ccctgtctct cagcttgacc tatttagtag aagctggtga gttgagcttg
     5341 atggaattac ttgaaaaaat gacatacaac ccagccaagc tttacaactt tgaagcaggt
     5401 tacttggctg agaatggtcc agcagatatc actatttttg atgccaaggc tgaccgcttt
     5461 gtggactccc attttgcttc caaagcagct aattcaccat tcatcggtga aaccttaaaa
     5521 gggcaggtta aatataccat ctgtaaggga caaatcgtct atcaagcttg ataggagtta
     5581 gaatatgaat tattttcgaa aacgtaggga gagacaagcg aaatctaata gtggaattta
     5641 ctgtcccgca gctaatcgtt ccaaaattca atatgaaact aaagaaaaag ctgaccatgc
     5701 ggttcaatat gataacggag gtttagttag aagctattat tgtcgtacat gtgcgtgttg
     5761 gcatactact tcaaaatcta ataaacctcc gctaagtttg aaaaactatg gtctgaaact
     5821 ctttggttta gataaatcag aatagaaaga gaagtatgta taagacaaag tgtttacgag
     5881 agaagttagt attattttta aaaattttct tcccaatcct gatctaccaa tttgccaatt
     5941 attctgcctc ttttgttgat actgcaatga caggtcaata caacactatg gacttggctg
     6001 gtgtatctat ggcaaccagt atctggaatc ctttctttac atttctaaca gggattgtgt
     6061 cagccttggt gcctatcatt ggtcaccatc ttggtcgagg caaaaaggaa gaagttgcgt
     6121 ctgattttta ccaatttatt tatttggcct tgggcctatc tgtggtcttg ctggggatgg
     6181 tacttttctt ggcaccaata atcttgaatc atattgggtt agaagcagca gtagcggcag
     6241 tagcggttcg ctatctttgg tttttatcta tcgggattat ccccttgttg ctctttagcg
     6301 tcattcgttc cttgctggat tcgctgggct tgaccaaact gtccatgtac ctcatgcttt
     6361 tgttactccc tctcaatagc ggatttaact atctcttgat ttacggtgcc tttggtgttc
     6421 cagaactggg aggggctggt gctggtttag gaacatcctt ggcctactgg gtcttgcttg
     6481 ggatttctgt tctggtttta tttaaacagg agaagctcaa agccttacac cttgagaaac
     6541 gaattccact taatatggat aaaattaagg aaggagttcg tttaggtctg cctattgggg
     6601 gaactgtctt cgcggaagtg gctatctttt cagtggttgg cttgattatg gctaagtttt
     6661 cgcccttgat tatagctagt caccagtcag ctatgaactt ttcaagtctt atgtacgcct
     6721 ttcctatgag tatctcatcg gctatggcta ttgtcgtttc ctatgaagtg ggagccaagc
     6781 gatttgatga tgcgaaaacc tatattggtc taggaagatg gactgccctc atttttgcgg
     6841 ccttcacctt aaccttcctt tacattttta ggggaaatgt ggccagtctt tatggtaacg
     6901 acccaaaatt tatcgatttg acagtgcgtt ttttaactta tagtcttttc ttccagttag
     6961 cagatacctt tgcggcgccg cttcagggaa ttttgcgggg gtataaggat acagttattc
     7021 ctttttacct tggtttgctt ggttattggg gcgtagcaat ccctgtggct acgctatttg
     7081 attccctaac agattttgga gcttattctt actggatcgg cttgattatt agtttgattg
     7141 tgagcggggc gctctaccgt tggcgtttaa ctgtgattat gaagagattt gaatctttag
     7201 caaaatccaa atgctaaaaa gtttgtgaaa aaatattctt gacaagaaaa tcccttgttt
     7261 tcacggggtt ttctttttta ttttgtgaaa tttcttttag aaaaactttg acagtatttg
     7321 ccaaaagcgg taaaatagta aggtaagaag aaagttagaa aggcaagaag atgtcaactt
     7381 tagataaaaa tcttttgcta gaaatgttcc gtaagatgga agaaatccgt cgcatggact
     7441 taaaaattgc acaattagta aagaaaggga aagtgccagg aatgacgcac ttttctgttg
     7501 gtgaagaggc agctaacgtg ggggctatgt tagctctcaa tccagatgat ctgattacct
     7561 caaaccaccg tggacacggg caagctattg ctaaagggat tgacctcaac ggaatgatgg
     7621 ctgaaatcct tggtaaatac actggaacct gtaaagggaa aggtggatct atgcatatcg
     7681 ctgaccttga tgctgggaac cttggtgcca atggtatcgt aggtggtggt atggggatcg
     7741 ctgtcggtgc agccctcagt cagcaaatgc aaaataccgg taaaatcgtt gtctgcttct
     7801 ttggagatgg tgcgaccaat gaaggtgttt tccacgaagc agtgaacatg gcttctatct
     7861 ggaacctgcc agtcattttc tattgcatta acaacggtta cggtatctct gcggatatca
     7921 agaaaatgac caatatagaa catatccatc aacgtagcgc cgcttatgga attcctggaa
     7981 tgttcatcga agacggtaac aatgtcatcg atgtctatga aggatttcag aaagctgtgg
     8041 accatgttcg cagtggcaat ggtccagtct tgattgaaag tgtaacttat cgctggctcg
     8101 gtcactcatc atctgaccct ggtaaatatc gtacgcgtga agaagtggaa ttgtggaaac
     8161 aaaaagatcc aatcgaaaac ctccgcaatt accttattga aaataacatt gcaagtgccg
     8221 aagaattgga agaaatccaa gcgcaagtaa aggaagcagt agaagcttct gttaaatttg
     8281 cagaggaaag cccattccca ccgcttgaat cagcctttga agatatttac gcagactaag
     8341 gagaaagaga taaaatggaa acaaaaacaa tgtccttccg tgacaccatt atccttgcta
     8401 tgtctgagga aatgcgtcgc gatgaaaatg tgttcttgat gggagaagac gtcggtgtct
     8461 tcggaggaga cttcggtact tctgttggaa tgcttgaaga atttggtcca gaacgtgtcc
     8521 gtgactgtcc gatttctgaa gctgccatct ctggagcagc agcaggagca gccatgacag
     8581 gacttcgtcc aatcgtcgat atgaccttca tggacttctc tgttattgcc atggacaata
     8641 tcgtcaacca agctgctaaa acacgttaca tgtttggtgg taaaggtcag gttccaatga
     8701 ctgttcgttg tgcagctggt aacggagttg gctctgccgc ccagcactca caatctctag
     8761 agtcttggtt tactcacatt ccaggactta aggttgtggc acctggaaca cctgcggaca
     8821 tgaaaggcct gcttaagtct tctatccgtg ataacaaccc agttattata cttgagtaca
     8881 agtcagaatt taaccaaaaa ggggaagtgc cagttgatcc agactacaca attccacttg
     8941 gggttggtga aatcaaacgc caaggaacgg atgtaacagt tgttacttat ggaaaaatgc
     9001 ttcgccgtgt ggttcaagct gctgaagaat tagcagaaga aggaatttca gttgaaattg
     9061 ttgacccacg tacccttgtt ccgcttgata aggatatcat cataaactca gtgaagaaga
     9121 ctggtaaggt tgttctggtc aacgatgccc acaaaacaag tggctatatc ggtgaaattt
     9181 cagctattat ttcagaatca gaagcatttg actatctaga tgcaccaatt cgccgttgtg
     9241 caggagaaga tgtgccgatg ccttatgcac aaaacctaga aaatgcaatg attccaacag
     9301 ttgaaagtat caaagatgca atccgaaaaa cttataacaa agaatagggt tacataagat
     9361 aagttatgta aataaaataa agctgacgag aaactttgta tcttttaggt gcagagctct
     9421 tcgtcattaa tatcttagat tagagcacgg gctaaaagat cggaaaaaag ataaatctcc
     9481 ttggcttcat cgaagccatc gtcgatttcc tatttttcag tcgcttttga cgccctttgt
     9541 atcataaata gaattggaga ggtcatggct gatgacaagc taagagcgac tcctgcagct
     9601 agaaagttag cggatgattt agggataaac ctctacgacg tttctggctc aggtgcaaac
     9661 ggtcgtgtcc acaaagaaga cgtggaaact tataaagaca caaacgtggt tcgcatttcg
     9721 ccacttgcaa aacgaattgc cctcgaacat aacattgctt ggcaggaaat ccaaggaacc
     9781 ggtcatcgtg gtaaaatcat gaagaaggat gttttggccc tgcttcctga aaatatcgaa
     9841 aacgatagca tcaaatctcc tgctcagatt gaaaaagtgg aagaagtccc tgataacgta
     9901 acaccatatg gtaaaatcga gcgtattcca atgacaccaa tgcgtaaggt tattgcccaa
     9961 cgcatggttg aatcttactt gactgcgcca accttcaccc tcaactatga agttgatatg
    10021 actgaaatgt tggctcttcg taagaaggtt cttgagccaa tcatggaagc aactgggaag
    10081 aagactactg taacagacct tctttcgctt gcagttgtta agactcttat gaaacaccca
    10141 tacatcaacg cttcattgac agaagatggc aagactatta tcactcacaa ctatgtcaat
    10201 cttgccatgg cagttgggat ggataatgga ttgatgacac ctgttgttta caatgctgag
    10261 aagatgagtc tttcagaact ggttgtagcc tttaaggatg ttattggccg taccttggat
    10321 ggtaaattgg ctacaagtga gttacaaaat tcaacattca caatcagtaa tttgggaatg
    10381 tttggtgttc agtcctttgg tccgattatt aaccaaccca actcagctat ccttggtgtc
    10441 agttcgacaa tcgagaagcc agttgtcgtc aatggtgaaa ttgtgattcg cccaatcatg
    10501 agtttaggat taaccattga ccaccgtgtc gtagatggta tggctggtgc taagtttatg
    10561 aaggacttga aagagttgat tgaaacgcca atctcaatgt taatttaaga gcaagagtat
    10621 tcatttttaa gatatagata aaggaaggaa gacatggcct tagaagtaat tatgccaaaa
    10681 gccggcgtgg atatgacaga aggacaaatc gtccaatgga ataaaaaagt cggagaattt
    10741 gtaaaagaag gagaaatcct tttggaaatc atgactgata aagtcagcat ggaattggaa
    10801 gccgaagaag atgggtactt gattgccatt ctcaaaggag atggtgaaac tgtccctgta
    10861 acggaagtta tcggttacct tggtgaagaa agggaaaaca tcccaacagc tggagcagca
    10921 tcgccagaag ctagccctgt acctgtagca agtacctcaa acgatgatgg taagagcgat
    10981 gatgcttttg atatcgttgt gattggtgga ggtcctgctg gttatgttgc agccattaaa
    11041 gctgcccaat tcggcggtaa ggttgccctt gttgagaaat ctgaacttgg tggaacctgc
    11101 ttaaaccgtg gatgtattcc aaccaagacc taccttcata acgctgaaat tattgaaaat
    11161 atcggtcatg ctgcaaatcg tggtatcgtg attgaaaatc ctaacttcac tgttgatatg
    11221 gaaaaacttt tagaaactaa atctaaagtt gttaatactc ttgttggtgg tgttgcagga
    11281 cttcttcgta gctacggagt tactgttcat aaaggaattg gtacaatcac taaagacaag
    11341 aacgtcttgg taaatggttc tgaattgctt gaaaccaaga aaatcattct tgctggtggt
    11401 tcaaaagtca gcaagatcaa cgtccctggt atggaatctc cacttgtcat gactagtgat
    11461 gacattcttg aaatgaacga agtgccagaa agccttgtta tcatcggtgg tggagttgtc
    11521 ggtatcgaac tcggtcaggc cttcatgaca tttggttcaa aagtgactgt tatcgaaatg
    11581 atggaccgta tagttccagc tatggatgtg gaagtttcta agaaccttcg cttgattctt
    11641 gagcgtaaag gaatgaccat cttgactggt actaaactgc aagaaatcat tgaggaaaat
    11701 ggtcaacttc gtatcaaggt tgaaggaaaa gacgatatca tcgcaagcaa agctcttctt
    11761 tcaattggtc gtatgccaga ccttgaaggt attggagagg ttgagtttga attggatcgt
    11821 ggttgtatca aggtcaacga atacatggaa acttcagttc caggcattta tgcaccaggt
    11881 gacatcaacg gtactaagat gttggctcac gcagctttcc gcatgggtga agtttccgct
    11941 gaaaatgccc ttaaaggaaa tcatgcagtt gccaaattga atttgactcc tgcagccatc
    12001 tacactctcc ctgaagtagc agcagtaggt ttgacagaag aacaagcccg tgagaaatac
    12061 gatgttgcca tcggtaagtt taactttgct gctaacggtc gtgctattgc atctgacgca
    12121 gctcaaggtt tcgtaaaagt tatcgctgat aagaaatacg gagaaatcct tggtgtacac
    12181 attattggtc ctgcagccgc agaattaata aacgaagcat caagcatcat cgaaatggaa
    12241 atcactgttg aggaaatgct gaagaccatc cacgggcacc caacttactc tgaagtgatg
    12301 tacgaagcgt ttgcagatgt tctaggaatg gccatccatt cacctaagaa aaaataaaac
    12361 gaagatagat tagactggaa ggttatttcc agtttctatc atataaagta aagggatatc
    12421 atgaaataca ttatcaatca ttcaaatgac actgctttta atattgcctt ggaagaatac
    12481 gcctttaaac accttttgga tgaggatcaa atcttcctac tttggattaa caagccatct
    12541 atcattgttg gtcgtcacca gaacactatc gaagaaatca accgtgatta tgttcgcgaa
    12601 aatggtattg aggtagttcg ccgtattagt ggtggtggag ctgtttacca cgatttaaat
    12661 aacctcaact acacgatcat ctccaaagaa gatgaaaata aggcatttga cttcaagagc
    12721 ttctcaactc cggttatcaa taccctggct caacttgggg ttaaagctga gttcacaggt
    12781 cgtaatgacc ttgagattga tggtaagaag ttctgtggca atgcccaagc ctatatcaac
    12841 ggccgtatca tgcaccacgg ttgcttgctc tttgacgttg atttgtcagt cctcgcaaat
    12901 gcccttaagg tttcaaaaga taaatttgaa tcaaaaggtg tgaaatccgt ccgtgcccgt
    12961 gtaaccaata ttatcaatga attaccaaaa aaaatcacag tcgaaaaatt ccgtgattta
    13021 ctcttggaat acatgaaaaa agagtaccca gagatgactg aatacgtctt ttcagaagaa
    13081 gaattggccg aaatcaatcg catcaaggat actaagtttg gaacttggga ctggaactat
    13141 ggtaaatcac ctgaatttaa cgtccgtcgt ggaatcaaat tcactagtgg taaggttgaa
    13201 gtctttgcta acgttactga atcaaaaatc caagacatca agatttatgg tgacttcttt
    13261 ggtattgaag acgttgctgc agtagaagat gtccttcgtg gggtgaaata cgaacgcgaa
    13321 gatgttctta aggcgctaaa aaccattgat atcacacgct acttcgctgg tattagccgt
    13381 gaagaaatcg ctgaagcggt agttggataa atcaaaaaga agttggccaa ctaaccaact
    13441 tctttttttg atatttattt acataattta aaatacgtaa aatcataaac tatccagagc
    13501 attcttttgt tcatcactaa caatatgggt atagaggtca gtgacttgtg tgctagcatg
    13561 tcctagttgg tgactgacta aaacttgtga tttagtcgca tcatagagcc tagttgctag
    13621 tgtatggcgc agtttatggg gtgttacacg cactttaaaa tcctctgagt atttagcaac
    13681 cattttctca acgctagaag catcgatacg attaggaaca cctctgtaga gagttaaaaa
    13741 aagggctgta tctgtttttt ccgttttata gcgttgattc cgaatggcca gataattctc
    13801 taaataaggt ttagcaaaag cagcgacatt gactgagtca cgtttgcaac cttttcgagt
    13861 aacatcaata accatcattt ttagattgag atctcttaga tctagattaa cagcttcaga
    13921 taagcgaaca ccagatgcca agagaagggc aataatggct aaatctcgtt ctttattttt
    13981 gttgaatgat gagagagctc gatttgaaag ctgttgtggg tgctcttgat cgatataagt
    14041 tagaaaacct tctgtttcat cacctagaaa gagtttttgc ttgatatttt cagctctggc
    14101 agcaagggtt tctttctttt tcttggtgga aacttttttc attacattac gatagaaata
    14161 aggttccccc tgatcgtttt caacctcctc ggttagatac ttgtaaagac tagaaagtgc
    14221 tgataaggtt cgattgatag ttgtctgtga aacaccttgt tttgttgtat tagcattcag
    14281 caagggacgt tcacgtagat aaaggataaa ggattccatg tctttcttag acatattttc
    14341 caaaactgat aaaggaatat cggatatttt atcagcgttt gaaataccag actccaaaac
    14401 ccagctgaaa aatcggtcat attccttaag gtattcgtac agggttgtaa aactgtaggg
    14461 cacagccagc ttagattggt agtattccag aacataccag ggcatgagtt gttttagttt
    14521 gtcgattcgt tccagtaaaa tctcacgttt catgtatttt ctccataagt aagtatacta
    14581 gtagtatagc atagacttgt atatttttca agaaaattat agtttttcgg aaagatgtta
    14641 taggagtttt tcaaagtgat aaaaagactt agacctacaa acaaaacaga ataaggaaaa
    14701 taataaaaat ctcacccact aaacttctgt taatactaca taactgaaga gctatataag
    14761 gagctatgag atacaaaaca cattgtataa tagattgaaa ctagaatagt acatctggac
    14821 ttctaaaaca ttgctagaaa ttgatttgat tgtcctgatt gttttatcct atttctattt
    14881 catttctcta tataattgct attgttttct ttttcatgat tttaatctta ctgtacagat
    14941 ttgatacagt aaactccttt ctagctttat actttatcat ttctaactta attatagtct
    15001 tatttttaat aaagttcaat tatttatatg taaaattcct catcagtaaa aaataaccga
    15061 tctcattcct gagaatcggt tttctaaata aatcaaactg atcatttaca taacataaat
    15121 tatgtaaata ctcatactac aacaacaaat ctttgacttt tccaatttca ctttttggaa
    15181 taaccaggtg aatcatatca cccagataca ttctggttga gccgttaact gtttggctct
    15241 tgccattatg gacttgagtt gtgatgagga cgttgtgtgg taagttgagt tcatgaactt
    15301 gtttcccagc aattttatca gaaactggta tttcgataag tgtaacttct ccttcgctag
    15361 atacttcttc tggaagcatt ttttccagca tggcttcata gactggcgta cctttgagca
    15421 aatccatgat aatataagaa acaagagtga caagaccaag tggcataagg ttgcgaatat
    15481 ctcctaccat ctcagttacg aggatcatag cggttaaggg agcttttgat atggctccaa
    15541 aatagccact cattcctaga atgacaaata tagggaattg ctcttgactg acaagtccaa
    15601 gattgacaca gataacacca actaaggcac caagcaaaga accaagagct aaaatgggga
    15661 ggaaaattcc tcctggcagt ccacttccat agctaatcat actccaaata aagcggatta
    15721 aaaagtaagc taataaaact tggaaactaa aattttgttc agttaaagaa aggacaagct
    15781 gatttccgcc accaatgatt tgaggtaaga agattccgac tggtatgata aggataaaag
    15841 ccaagatggg ataataagcc ctatccaaat ggattttttg accaatcaag tcataaactc
    15901 ttccaacgtt taatacagct ttctcataga gaaaacctga aaatccaagg aaaattccca
    15961 tgacgagata tatccaatac tgatctaggg tcatgggagg aatgttatct ggcatatcca
    16021 atactggtgt caaaccgaac atgagtagag acacaaagtt tgctacgatg ctggctgcta
    16081 gagttgagac ccagaaaaag cgcgaaaaat ggtgatagac ttcttctaca acaaagagaa
    16141 gtgctgcaat aggagcatta aaggctgcgg ctaaacctgc tgcagctcca ctggcaatca
    16201 aggaacgttc ctctactgga ctggatttga gccacttggc aattccttta ccaccaactg
    16261 ctccaagttg aatgctgggt ccctctcgac ccagcatgag tccactggca atagcaagaa
    16321 tacctagcac atattttttc caaagaatgc cccaccagtt gagggacatg aggcctttca
    16381 gttcggcttc gacttgagga attcctgagc ctttaatatc tttttctgac cgtgttagtt
    16441 tggcactgag ccaacagatg agtatataaa acaaaaccag tacaaaaaga ttgcgcacta
    16501 agtacccttg atcttgataa actccttgta tcaggtggaa gcccttttca attaagaaac
    16561 gaaaggatcc gacgataatt ccaacgatga ggccgacaat gattcctcga ccaacttggg
    16621 atagtatagt gctggatgca aaggcgaatt ctttcttaga acggactatt tccgactgtt
    16681 cctccatgtt atttcctttc aattaacttt cttttttacc taaaaccagt gatttaacgg
    16741 gttcaaagct ggttcggtga attggggtaa ctcctagttt tgtgaggcct tccagatgtt
    16801 tagctgtgcc atatcctgca ttagtagcga aatcatagcc agggaactgc tgatcgtatt
    16861 ctttcagcaa ttcatcacgt gttaccttgg ctactataga tgctgctgcg atagagaggg
    16921 agttggcatc tcctttgata atggaggttt gtgaaatggg caagtccagt ttcatggcat
    16981 caatcaaaag gtgctctggt tgagggctga gctgggagat tgcttcttgc atggctagtt
    17041 tggttgcttc atagatgttg acttggtcga tgacctgatt atctatgata ccaattccaa
    17101 tcgacaaggc ttggtcttga acggcttgga aaatctccag atgtttcttt ttaggaattt
    17161 tcttgctgtc gttgagacct ttaatcttac aatttttaga taaaataacg gccgcagcga
    17221 ctacaggacc agcaagagga ccacgaccaa cctcatcaat acctgcaatt aaggtcaatc
    17281 cttgcttata aagttctttt tcataagaaa gcatggattc caagcgcaaa ttttcatcta
    17341 attcagcttg aatggctctt ttacgcttgc tgatttcctt ttgaactcct gagcgattat
    17401 ccttttcaag ctctaaaaaa atagggcttt ctaactcctt gactgtcaca aggaattctt
    17461 tgatttcttt aatcgttgcc atcgaggtct tccaatgtat ctaaggtata gttaccgagt
    17521 ttgccatcac ggacttcctt cacgaagaga ctgtaaaaac ggtcatagtc atcacggaaa
    17581 ccgagggcgc gggtcatatc cataataatc acaggcgctt cttcttcaat tttcatttgt
    17641 ttgaagcgtt cagccagctt ttctggataa tgttctttga aataattgat accaaaaatg
    17701 gtaacctcat ccataggaag caactggtct ttgatagctc cagtcaatgc caacttaagt
    17761 gcaacagttt catcctcaaa cttaggccag agaatccccg gtgtatccaa gatttccagg
    17821 tctttattgg ttttaagcca ttgttgacct tttgtgaccc ctggcttgtt tccaacaaca
    17881 gcaatctttt taccagccaa acggttcatc agagttgatt taccagcgtt tggaatcccg
    17941 ataatcatag tacgcaaggt ttcaatctga atcccacgtt ctttctggcg agcaatctta
    18001 tcagccatga gcttcttggc cgcatctgtt acaactttta cagtcacttg ctctttggag
    18061 ttgatagcta gcgtctggat tccttgtgat tcaaaatact gacgccattc cttggtcatt
    18121 gctggatcag ccaagtcggc cttgtttaaa atcaagagtt ttggtttatc accaacaatc
    18181 ttggtcaaca taggattttg actagataga ggcaagcgtg catctactaa aatcgtcaca
    18241 aaatcaacaa attttaaatt ctcctgcacc tgtcgacgag ctttagacat gtgaccagga
    18301 aaccattgaa tagtagccat tgagtttttt cctttcatag caaggattta gatcccctat
    18361 tttattttac tattgtttga acatagagag ttttcaaatg aatgatgtcc aaacagttct
    18421 tgttttatga catagaaatc tactttatat tatatcatgc cttctttatt ttgtccgatg
    18481 atagcctttt accctatctt ttaccctata tagaaaaaag ccatcaaatg atgacttttc
    18541 agagggagca aaaaactgtt cccgtcatat tatgaaccaa aagaactaaa ctaccaacag
    18601 ctaataggcc taaagctgta agctcagaag ttgatgaacc tgttgcagga agagtttcct
    18661 gctgataaat aagatcataa cttacttcat tatcagtagg aattcctgct tgaatcttgg
    18721 tttgttcttc atcacctttt taaactttat ttcctaatag tagacactat tttttattct
    18781 caaaaattga acttctaaaa tcatttgttt ggtcaagata ggctttaaag attgctctct
    18841 tgagcttgtg gacttcacta tctatgtctg gattgtagtt attccaatgg tagtaattgt
    18901 gttctgcatc cttacgaaca gcaacgtcca ttaatttctg taattcatct acactgcttg
    18961 tagttttctt ggcaaatgtt tgccaaggct gtgttgtatc attaaaagta actttgttca
    19021 atctatcaaa ctgatcttgt cgttcttgat acatagcttt cttaaactca ctccaagtat
    19081 gatattggtt attaaatacc ttttccaaaa ccaagtcatc tgtaaccaaa cctcttgttt
    19141 taccgtagag attgattgtc ttgccctttt gtttggcttc ttcttcgtat tggtttgaga
    19201 tatatggtac cataccatct ttaaagcctt tagcagctag tagttcatag gctatacgac
    19261 gtcccatcag gtcacctggt gttcctatat cattacttaa tgcagcataa atcggtgcaa
    19321 ataacttaat agtgaagtag ccatttcttt cgtatttacc tgaggcatat tccctagacg
    19381 aaagaatatt attatcaatc aaatcattga atgaacgtag tctttcaact tcttctactg
    19441 ttagatttct gacaacattt gttgcataga ccttatttcc atcaggatca ggatggtact
    19501 catttgtaac ttttctaaga agttgttgtt tttgattcgt atccaattta agaattgaat
    19561 ttccttcgag atattccaac atataaacaa cgtcaaacat gttgtggaca tattgcttca
    19621 aatcatctgc attattaaat cttgtagttg gatcaagtac ttgtaatcgt cgactttctg
    19681 tactatcaga ttttgaatgt ttcaagatgg agttgatggt aatggtcgca tcatctggat
    19741 ggtctggtgc ttgtaataat cctttagcaa agaactctgg tcccaagcca cttcttcgac
    19801 catatcctcc aagataaatg tcctgatctg agtcatgtgt catctcatgc gtataagtaa
    19861 tagctccatc cttatccaac attcgataac ccatataata aactgcatca cctgtagcat
    19921 aagcaccgtg ttgattatgc ccaactttat ttccaacagg tccaaagaaa tgttgcattg
    19981 caggatttgg attatcaaaa tctgccactt ctgtagcttt ccctacggta ttatcatcgc
    20041 caaatttata agcatcgtaa agcaaaatat ttctataaag tttttcacgt gcattgtcgt
    20101 ctaaaatacg ataccaataa tcgtagtgat ctcgctgacg tttggctgtt tcacgcgcat
    20161 tttcttcaac aaaatcattg agagccttgc ccgctttatg gtcactactg cggtagcgat
    20221 cataagctcc aaatcctaga ctagacatgg tcgagatgac aaatacggat ctctctggca
    20281 aggtcaggag aggcaagacc atattgcggt atttccatgt ggcactcgtg atacgatcat
    20341 aaacaccgat agaatacttg gtgctagcta acccttgctt cgttttcacc tcttcgatag
    20401 tggatttttc ttcgacaatg taagccttag tctctgattt aaaccagtca ttattgcttg
    20461 tatttggtaa aaagactttt cggtaatgtt ccagcgtgct aaacaaatct gtcgttccat
    20521 gttgactggc aagactgata ccataagtat cgacattatt cttagctaga agattgttaa
    20581 agccagattt acccaactca atcagagtat ctaatggtga agcattcccc ttaccaaaga
    20641 agtccaaatg gtacagaact aggtctttga cattcacctg accatagcta aagttatacc
    20701 accgttccag ataggtcaag ccaagtagca aggcttcctt gttgcgtttg attttatcta
    20761 caagataacc ttcagtgact gggttagcac tagccagtcc agcatccgct gacaagagtt
    20821 ttttcaaact gtcttccagt tgttgttttg ttttggcgaa ctggtcttct agatagagct
    20881 cagtttgctt gacgtttgga gaaataccca gcgtctttct gatggcttct gaatgatagt
    20941 caaccttttg taagtcaagt aagacttgct tgatgataga ggtttggtca tacaggaatt
    21001 ggtttggcgt atagagaagt ccagtattgc ccagactata ttctgctaat ttggcgaaat
    21061 cattctggta tttgagatcc agcttctcag ataaatcatc cttgtagtga agcaagagtt
    21121 tgtttgcagt ctgtttgtta gaaacaatgt ctgtgatgac ttggttgtcc ttcatcacga
    21181 ctgctgacaa gagttctttt tgatataaaa gactgttctc attgaccaga tttccgtatt
    21241 tgacgatggt tgccttgttg tagaaaggta gcaatttttc aatgttttta taagtcaagt
    21301 tgcgcttagc ttgataatag gccaccttag aaaaatcact gtcttttttg ccacttgttg
    21361 aaagtggctc cactgttggt agaatgagag gattgatttc tgcttttttg cttgcaattt
    21421 gagaagcatc tagcattgtt cctctttctt caaaggattc cttgctgacg acctcatcct
    21481 tgaccaaggt gacattgtag actctgttgt ccttgctgct gaatgtgtcc tttaccttca
    21541 tttcgttata gtggtaacca gtgatggcat ttccgttggt tacattaaca tcgctgagaa
    21601 cattggtcaa acttccagca tgcctaacat caccagaagt tcgatcccac aaattgcctg
    21661 ccactccagc gactctacca aagtgcttga cattgttgat atcaccttca gcatagctat
    21721 cttggatctg tgcatctcgg tctactaggc ctgcaagtcc acccacagtc tgatctgaag
    21781 tatttgtgtt agatgaaatg gccactgtcg cttttgactt agtaagtaaa gccttgtcac
    21841 ctgtcaaatg accgaccata ccaccgatat tgtaggcagc agtcgtttca taggtattga
    21901 caattcttcc cttgaaacta ctctctgtga tgcttgattg atctgcctta gccaacaaac
    21961 caccgatacc acgttcaccg gcaagtacac catccacatg aacttgctta atttttgtgt
    22021 tattctgagc ttcatttgcc agtgaaccga tatcatcttt ccctgaaata gagacatttt
    22081 tcagactcaa cttttctatt gtggcccctc tcaagctttc aaaaagaggc tttttcaagt
    22141 tgtaaatagc ataatgctta ccatcttttt caccaatcaa ctgaccagta aaggttccct
    22201 tgatatagga tttatcatca gtactaagct ccacttcgtt agcattcagg ctagctccta
    22261 aatgataggt tccagagaga ttttggttta tagctttgac cagattacta aaggaagtaa
    22321 agtttgttgt ttcttctgtt cccttcttag ctagatagaa ggtaaaatta tctttatatc
    22381 tgctttctat ctcctgctga agcttctcta cttttgctgt gattttataa aggattttat
    22441 cattttttct ttcctctgat attgatgcta ctggtaggta tacatctttg aatgaagaag
    22501 atttcacttt aacaaagtag ctatttggat tgcttggaac ttgctctaac gaaatgtgtt
    22561 gtttataagt accatttgac aaactgtata actctaggtc ggaaacattt cttaattcaa
    22621 gtgttttctc tggttcttct acctttttat cagggtctag ttcattttct tgtttaattt
    22681 cttcgtttcc atttgaattg gatgtgtttg attcggttga aacatcctca gttgaatttc
    22741 cgtttgatgg ttctggttct gtttgtccat tctctgatgt tgtattacct gaattttctg
    22801 gttttgttgc agttccgttt ttttctggtt
//
LOCUS       DAVEHY010000036        21932 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVEHY010000036 DAVEHY010000000
VERSION     DAVEHY010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21932
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.036"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            49..321
                     /locus_tag="VUZ44_001667"
                     /pseudo
     CDS             49..321
                     /locus_tag="VUZ44_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(432..635)
                     /locus_tag="VUZ44_001668"
     CDS             complement(432..635)
                     /locus_tag="VUZ44_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU0320542.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(666..1274)
                     /locus_tag="VUZ44_001669"
     CDS             complement(666..1274)
                     /locus_tag="VUZ44_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU0320543.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(1313..1483)
                     /locus_tag="VUZ44_001670"
     CDS             complement(1313..1483)
                     /locus_tag="VUZ44_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU0320544.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(1495..2061)
                     /gene="amaP"
                     /locus_tag="VUZ44_001671"
     CDS             complement(1495..2061)
                     /gene="amaP"
                     /locus_tag="VUZ44_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU0320545.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(2145..2309)
                     /locus_tag="VUZ44_001672"
     CDS             complement(2145..2309)
                     /locus_tag="VUZ44_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU0320546.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            2752..4233
                     /locus_tag="VUZ44_001673"
     CDS             2752..4233
                     /locus_tag="VUZ44_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0320547.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            4595..5590
                     /locus_tag="VUZ44_001674"
     CDS             4595..5590
                     /locus_tag="VUZ44_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU0320548.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIAIPTYFWGDKTTKKI"
     gene            5717..7027
                     /locus_tag="VUZ44_001675"
     CDS             5717..7027
                     /locus_tag="VUZ44_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU0320549.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            7123..8025
                     /locus_tag="VUZ44_001676"
     CDS             7123..8025
                     /locus_tag="VUZ44_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU0320550.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYTFTDYYLLTPDERKFVGFENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            8027..8872
                     /locus_tag="VUZ44_001677"
     CDS             8027..8872
                     /locus_tag="VUZ44_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU0320551.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFLGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRFAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            8882..10201
                     /locus_tag="VUZ44_001678"
     CDS             8882..10201
                     /locus_tag="VUZ44_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU0320552.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGYIEEKTGVHQVQNLAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHMDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(10409..10481)
                     /locus_tag="VUZ44_001679"
     tRNA            complement(10409..10481)
                     /locus_tag="VUZ44_001679"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10446..10448),aa:Lys,seq:ctt)
     gene            complement(10746..12017)
                     /locus_tag="VUZ44_001680"
     CDS             complement(10746..12017)
                     /locus_tag="VUZ44_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU0320553.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            12287..12526
                     /locus_tag="VUZ44_001681"
     CDS             12287..12526
                     /locus_tag="VUZ44_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320554.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            12691..12870
                     /locus_tag="VUZ44_001682"
     CDS             12691..12870
                     /locus_tag="VUZ44_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320555.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            13007..13186
                     /locus_tag="VUZ44_001683"
     CDS             13007..13186
                     /locus_tag="VUZ44_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU0320556.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            13223..13675
                     /locus_tag="VUZ44_001684"
     CDS             13223..13675
                     /locus_tag="VUZ44_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU0320557.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            13966..14436
                     /locus_tag="VUZ44_001685"
     CDS             13966..14436
                     /locus_tag="VUZ44_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU0320558.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            14455..15543
                     /locus_tag="VUZ44_001686"
     CDS             14455..15543
                     /locus_tag="VUZ44_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU0320559.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENSKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVRKDVVQTHKAMKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            15524..15952
                     /locus_tag="VUZ44_001687"
     CDS             15524..15952
                     /locus_tag="VUZ44_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU0320560.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECAAREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSLFMVGQLRQEQFDN
                     IIFGDEGQGYKLMPIEEFLNSKQAVPQLQGRLRDYLEESL"
     gene            15949..16422
                     /locus_tag="VUZ44_001688"
     CDS             15949..16422
                     /locus_tag="VUZ44_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320561.1"
                     /translation="MITLVRAGAEDLETIIAIQRASFKAVYEKYHDEYDPYLEDCERI
                     KWKLVERPNSYYYFVKEDEENIGFLRVQTNAELTKAWLGTAAILPQYQGKGYGSKGLS
                     LLEKEFPTITQWDLCTVLQDAGMVAFYEKNGYRQIHIEAEKEGMDMVYMKKLIEK"
     gene            16557..17510
                     /locus_tag="VUZ44_001689"
     CDS             16557..17510
                     /locus_tag="VUZ44_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU0320562.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDK
                     WDMVRESAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            17512..18255
                     /locus_tag="VUZ44_001690"
     CDS             17512..18255
                     /locus_tag="VUZ44_001690"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU0320563.1"
                     /translation="MQQYFVKGSAISPVTIEDKEISKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            18266..20062
                     /gene="pepF"
                     /locus_tag="VUZ44_001691"
     CDS             18266..20062
                     /gene="pepF"
                     /locus_tag="VUZ44_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU0320564.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            20309..21100
                     /locus_tag="VUZ44_001692"
     CDS             20309..21100
                     /locus_tag="VUZ44_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU0320565.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            21211..21879
                     /locus_tag="VUZ44_001693"
     CDS             21211..21879
                     /locus_tag="VUZ44_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU0320566.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         6767 a         3700 c         4614 g         6851 t
ORIGIN      
        1 gggagataga aagcaaacag ccttgaaatc aatgttgact gcgattatga acctgaatca
       61 gcccctcaaa agggactgta tatgaatgaa cgttaccagt gtttaaaaac taaagaatat
      121 caggcacttt tatcttccaa gggtagacaa attttcgcta aacgtaagat tgatatgaaa
      181 tctgtctttg ggcagataaa ggtttgtttg ggttataaga gatgtcatct gagaggtaag
      241 cgtcaagtga gaattgacat gggattcata ctcatggcca acaacctgct gaaatataat
      301 aagagaaaga ggcaaaatta aaaagctaga gttccgcaat tgggaatctc tagctttttg
      361 ttttctgaga atcatcttga ctcagactct tttgactaat gttaccaaaa aagataaagt
      421 aacttttaac cttatttatc gtcgccactc aacatgtttt taacaccttc tacagcacct
      481 tctacagcgt ctttagcgtc ttcggcaact tcttttactt tagaaacaac tttttcagct
      541 gctccttctt tttccatttt ttcatcaccg atggctttcc caacaccttc tttaatagaa
      601 cctttagctt gatttaattt ttcttctact gacatgataa tttctcctgt tatatttatt
      661 ttatcttagt ttacacgagt gttttcgtga gatactacac catttgctgc acctttaaca
      721 gcttctacac cttcgctaac tttttcttga acagttgaga aaccagatcc aagaccagat
      781 ttagcttttt cgaattgttc tgaagtgaat tctcctgttg attcagcaac gtcagatacg
      841 cgatcttgaa ggcttactga gtctgcttca tgctgttctt tagttttgat gtcgacaacg
      901 tttacgttga tttcaacaat ttccaagtca gtcattttag caacttctga agatacgatt
      961 tctctgattt ctgaatataa agctggaaca tttttttggt actcaacaat aacgtttaag
     1021 tcaactgcaa cttgtgtttt accaacttct acgttaacac cacttgttac gtcatcgctg
     1081 ttaacgattt tttctttaag atttgagaag aaaccaccat cgattcccaa aagacctgaa
     1141 acgttttcta gtgaaagacc aatgattttt tggataactt tatcttcgta agtaagttcc
     1201 cctttgattt cgtgagctac aacagtagca tctttctttt ctacgttagt gtttgtgttt
     1261 ttttcgtttg acatatgaaa ctcctttaat taaattagta atttttattt ttttatttat
     1321 ctatatagtt tttttcgata tataatccag ctgcaactcc cagtgctcct aaaatcaata
     1381 caaatattgt tttgaagaag ccaaaggaga caatcaaaca agccagaaat acgcctatga
     1441 gaccagcgat aattggatat cgatattgtt taagccattc cattttttac ttccttactt
     1501 cacacgacta acagtctttt tgttttgagg ttttggttgg taatttttta ctgcaacttc
     1561 aagttttact tgacgctcaa taccaaaaaa ctgcttcaat ccattagtta tttcattttg
     1621 aattatttgg catctgtcag cgatgttgtc tgaaggaaga attttacctt ctacatgaac
     1681 gaaacattta ttttttcgta aatttacatg aacagttggg ttcttgatca atctatgatc
     1741 actcaccaaa cttctaacaa aaccttcgat tgccgaattc tttaatttta atgtatcgtt
     1801 tttagtttca agttggattt ccaagtaacg tttaggataa aacatcacaa ctaaaatgga
     1861 taataaaact aaagttgata gaaccactgt cccccaaaag acatatctag caagatagaa
     1921 ttcaactacg gagttctgtc tccagctaag tagatgaata cctagatcac taacttgatg
     1981 ataatctatc aaaacaggaa ggaaaattgt caagattaaa atacagaaaa taatgaaaca
     2041 tattttcttt gcttttgaca tatacaatcc tttcgattta acatttaaac tatttttccc
     2101 gtcattgatt taaaaatagt ttgctaactt tactggcgaa aagtttactt tctacctgta
     2161 aagaatgaca ctacagtaat cacaatcgct gcacctacaa tagatgggag caaagccatt
     2221 ccagcgattg atggacccca actacctaaa agagattgtc ctgcatatgc cccgactaaa
     2281 ccagcgaata catttgcgat gattcccata gaactacttt tttagtgatt ttacctgcca
     2341 agagaccaat aagacctcca gcaataattg atcacaacac tgcctaccct ccttttttat
     2401 tttaatatca aaaaatcaat ttctttgatt aatactatta tataacttta atatagaaaa
     2461 gtcaattatt tcgattgtta ttattatata attttaaaaa atcaaattct ttaattgttg
     2521 ctattatata atttttaaaa ttaaaaatat aatctttaga cttgaatttg attctgtatt
     2581 cacgccctca atagacggta aaataagaaa attgtttata tattgtctcc gtagtgttat
     2641 tatacgaaat aaaagatttt aggaaaagtc gttatatcat gctataccta ttctttgtgg
     2701 tataattgca agaggtttaa tccgataatt tataaagaga gaaagatatt catgagagat
     2761 ttattatcta aaaaaagtca taggcaatta gaattattag aattattatt tgaacataaa
     2821 cgttggtttc atcgttctga actagcagag ttattaaatt gtacagaacg tgcagtcaaa
     2881 gatgatctat cccatgttaa atctgctttt cctgacttga tttttcattc ttctactaat
     2941 ggtatacgca ttattaatac cgatgatagt gatattgaaa tggtttacca tcatttcttt
     3001 aaacattcaa ctcatttttc gattttagaa ttcatcttct ttaatgaagg ttgtcaagct
     3061 gagagtattt gtaaagaatt ttatatcagt tcatcttcgc tctatcgtat tattagccaa
     3121 atcaataaag tgattaaaag gcaatttcaa tttgaagtca gtctgacccc tgttcaaatc
     3181 attggaaatg agagagacat tcgttacttt tttgcacaat atttttcaga aaaatattat
     3241 ttcctagaat ggccatttga aaatttttca tcagagccac tatctcaatt gttagaattg
     3301 gtttataagg aaacaagctt tccaatgaat ttgtcaacgc atagaatgct aaagttgctc
     3361 ctagttacga acctatatag aataaagttt ggtcatttta tggaagtaga taaagattct
     3421 tttaacgacc aaagtttgga ttttttaatg caggcagaag gaatagaagg tgttgctcag
     3481 agttttgaat cagaatacaa tatctcttta gatgaagaag ttgtttgcca attatttgtg
     3541 tcttactttc aaaaaatgtt tttcatagat gaaagtctct ttatgaaatg cgtaaaaaag
     3601 gatagttatg ttgaaaaatc ttaccatcta ttgagtgatt ttattgatca gatttcagtc
     3661 aagtatcaga ttgaaatgga gaataaggat aatctgattt ggcatctgca taataccgca
     3721 catctgtatc gtcaagagtt gtttactgag tttattttat ttgatcaaaa agggaataca
     3781 atcaggaact ttcaaaatat ttttccaaaa tttgtttcag atataaaaaa agagctttct
     3841 cactatttag agactcttga ggtttgttct agttcaatga tggtaaatca tctatcttat
     3901 accttcatca ctcataccaa acatttggtg attaatttgc tacaaaatca gcctaaacta
     3961 aaggttttag ttatgagtaa ttttgatcag tatcatgcaa aattcgttgc agagacactt
     4021 tcttattact gtagcaataa ttttgaactg gaagtttgga ctgaattaga attatcaaag
     4081 gaatctttag aagattcatc ttatgatatc attatttcta attttattat tcctcctatt
     4141 gaaaataaga gactcatcta ttcaaataat ataaacacgg tctcactcat atatttgtta
     4201 aatgccatga tgtttattcg attagatgag taaccaaaaa taacaaaaaa acgctatttc
     4261 gcgtttgaac tgtacctcaa aagttagaca gaaaaagtct aatttttggg gtgtttttgt
     4321 taagaaaata ccttcaatca tttaagcaaa atgtacatct agatttatag ccatctaaaa
     4381 ctcttgcttt ttttgtagaa gatacgaaaa aagccatgaa accaaggctt ttcctgtttt
     4441 atgtagatgt ttacacatga aaattgaagt attttcaaaa gctaattgga gtgattttat
     4501 tcatgatggg ataaatgatc tggccaaaaa tgattgagaa atagttgctt aaaaagcatt
     4561 tgcatgatac tatatattga aaggaggtga taatatggta gaacaaagaa aatcaattac
     4621 catgaaagat gttgctttag aagcaggagt tagtgttgga actgtttcac gtgtaattaa
     4681 taaagaaaaa ggcattaaag aagtaacttt aaggaaagtt caaagggcta taaaaacatt
     4741 ggactatatc cctgataatt atgctcgagg tatgaaaaag aatagaacag aaactatcgc
     4801 tttgattatt ccgagcatat ggcatccatt tttttcggag tttgcctatc atgttgagaa
     4861 agagttatta aaatataatt ataaattatt tatttgtaac gctgatagcg attcacaaaa
     4921 tgaaatcgaa tatatcgaaa tgttgaaaca aaataaagtg gatggaatta ttggtattac
     4981 atattctgat attgacaaat atattttatc tgatttaccg tttgtaagta tagatagaca
     5041 tttttcggaa aatgtatgct atgttacttc agcaaattac aaaggaggac aaactgcagc
     5101 agaggaactg gttagaaggg ataataagca ccttgctttt attggttcaa ttaatatgta
     5161 tgagaatgag actatactca gaagtaaagg attcagagaa aaagctaagg aattaggagt
     5221 agatgtctat aattttgaaa tgaaagaacc tttaataaat cctgaagatc agataagaat
     5281 ttttttgcaa tctcataaag aaattgatgg tatatttaca ataaatgata tgatggctct
     5341 gagagttatt agtgttatga aagaactggg gaaaatagca cctgatgatt accagataat
     5401 tgggtttgat ggtttaaaaa cttctgtcga tcaatcttat ctagtgtcta caatagttca
     5461 agatattggt atgatggcaa aagaatctgt tgcaatgata ctgaaaatga ttaagcgaga
     5521 agagattcta gaaaaacgaa tcgcaattcc cacatatttt tggggagata aaacaacaaa
     5581 aaaaatttaa aaagcgcttg acaattaatg aaagcgctgt tataatataa tcaacaaatg
     5641 aaacgtttca aaaataggct agaagcttgt ttaaaaaata aataaaaaat gaaacgtttc
     5701 aaaaaggagg aaaatgatgc gtaaaggtac aatgttatct gttgttgcgg ggctatcgtt
     5761 agctatactt gcaggttgta gtggaggaac taactcaaaa caagcgagtt cttcaaatga
     5821 tattaaagtc tgggtacaat tctctgacga aacaaatgaa ggaaaagctt ggcaaaaagt
     5881 tgttgataac tttaatcaat caggaaaaag taagtataag gttgtaactg agtatattcc
     5941 tcgtagtggt agtggtggag gatatgaaga caaggttaat gctgctatta cgactaatag
     6001 tcttccagat gttattaccc ttgatggacc aaatacggca gcttatgcaa aatctaaagt
     6061 aattactccg ctagatgatt atctaaaaga taataatatg gatgatgttt tggacagtat
     6121 taaacaacag ggaacttata atgggaaatt ctatgcattt ggattttctg aatcgaatgt
     6181 tggtgtttat tacaataaaa aaatgttcaa agaggccgga attgcggaat cagagcttcc
     6241 aacgctagaa aagccatgga catgggacga atttaatacg attgctaaaa aattgaaaga
     6301 tcattataac aaaccagcaa ttgattttcg tattaattca aacgatgaaa tgttgccata
     6361 tgcttatatg ccgttgattt ggtcaaataa tggttctgtc gtaaacgaag atggaacaaa
     6421 ggcagaagga tacttcaact ccaaagagag tgtagaagca gttcaattca ttcaaaatct
     6481 tgtaaaagaa ggctatacaa ctgttagtcc agtcgaaaaa ggttttgaaa caggagagta
     6541 tccaatgctt ttgagtggtt cttggacgat tgctgacatg aatacaaact acaaagatat
     6601 tgattttggt atccttcctt acccagtatc tagtaagacg aaaaaattag tatccccttc
     6661 aggtagttgg caattagctg tgacgacaaa atctgataaa aaagaggccg catctgaatt
     6721 tgttaaattt gctacaaata cagaatcaag tgaaattatt agcttgggga attcggtcct
     6781 tccaattcgt aaatctacaa ttgaaaatat caaagataaa gtatccgaac caatgcgttt
     6841 cttgatggaa caaaattcaa aaacagctca tgctcgccca gttgtcgtag catatcctca
     6901 ggtttctcga gcttttcaac aagcaatgca agatattagc tattatgaag aaaatccaaa
     6961 tgtgcaaaaa gtcttggata ctcgtacaaa agaaatgcaa actgctattg atcagtcact
     7021 caaataatct gtaaaaaaga aggtggaagg aaaatgtttg gaactacctt cccctttctt
     7081 gttaatagcc tagtttgata tatatgatta aaggagatgg atatgagtaa agaaactgtt
     7141 gtggatacaa aaagacgtga aaaaataaaa gataacatac taggttatag ttttttagct
     7201 ccagctttaa ttttattagg tatctttttg gtaattccag ttggaatggt catttattac
     7261 acttttacag attattattt gttgacacca gatgaaagaa aatttgttgg atttgagaat
     7321 tttattcgat taacaaaaga tccgattttc ttaaagagct tcttgaatac tttgaaattt
     7381 gttgtttgga ttattccagt tcaattggga gcggccttag gaatggcttt gattgtcaat
     7441 aaaaagcgaa aaggaaatat gttttttaaa gtggcttttt ttgctccagt tgtcatgtcc
     7501 ttggtagtta tttctattct ttggctttat cttttaaatc caaatagtgg cttattaaat
     7561 gctattttaa ataaggtagg tattgcttct caacctttct tgactagtcc taaacaagct
     7621 atgtatgcaa ttgtttttgt ttctgcttgg cagggtgcag gttatcagat gcttttattt
     7681 ttaggaggaa tgcagaatat tccacaagat gtctatgaag ctgctgaatt agatggattc
     7741 tcaaaatggg ctcagtttcg ttatatcacg atgcccctac taaaaccaac agccctgttt
     7801 gtattgttaa caactttaat ttctgctttt aagctgattg tacaaccaat ggttatgacg
     7861 caaggtgggc cattaaactc aacaattact atggtgtact atatttatca acaaggtttt
     7921 actgatcgtc ttgtaggata ttctagctca atcgctttag tatttacaac gttaattggt
     7981 atgattagct tagtacaacg tcgcgttctg aaggaggatg actaagatga aacgatttaa
     8041 accaacaaca atcttagaat atattctgtt aactttattg gcaggactct tcctttttcc
     8101 tatggtttgg atggtagttt cagctatgaa gccagaagcg gatgtttata aaaatttgac
     8161 tagttggcaa gccttcttac caagtttaaa tcccgctgat tggtttaaac cttatcagga
     8221 agtatttgag cgctttagta tttttacata tctagggaac agcatttttt atgctggaac
     8281 gtttgctatt ggttctatta ttgtcaatgc actggccggt tttgcttttg caaaagtcaa
     8341 ttttttaggt aagaaaattt tatttggttt cttacttgct ttacttatta ttccagtgga
     8401 aactgtgtta attccacaat ttaccattat caattcctta ggtttggtca ataatcgttt
     8461 tgcagttatt attccaggat tggcgagtgt atttaatatt tacttattta ggaatttctt
     8521 tattgcaatt ccagaagaga ttcttgagtc tgcaaagatg gacggagcaa gtatcgttag
     8581 aattttcttt agaattatgc ttccaatgtc taaacctgca gttgctacag ttggtgtttt
     8641 atcatttatt tcaagctgga atgattatat ctggccattg atggttttga cagattcttc
     8701 taaattttca atgcaggttg caattacaac tattaataca actcaaccag tttatatcaa
     8761 tcaggtaatg gctgtattaa ctatttcaac gattccgttg attttggtct atgtagtcgc
     8821 tcagaaatat attgttcaag gtctgggtgg ttccggaact ggaataaaat aggatatact
     8881 tatgataaat aaaacattta cagtagaaaa agccaatcgt tttatagcag aaaataaaca
     8941 tctcgttaat actcaatata agcctgaaga acatttttca gctgagattg gttggatcaa
     9001 tgatccaaat ggatttgttt attttcgtgg agaataccat ctcttttatc aattctatcc
     9061 atatgatagt gtttggggac ctatgcactg gggacatgct aaaagtaagg acttggtgac
     9121 ttgggagcac ttgccagtgg cacttgctcc tgaccaagat tatgaccgaa atggttgttt
     9181 ctcaggctct gccattgtca aggatgatcg cctctggctc atgtacactg ggtatatcga
     9241 agaaaaaacc ggtgtccacc aagtgcaaaa tctggcattt tcagatgacg ggattcactt
     9301 tgaaaagatt tcccaaaatc cagttgtaac tggaacagac ttgccagatg agttgattgc
     9361 tgctgatttc cgtgatccaa aactctttga aaaagatgga cgctattact ccgtagtagc
     9421 tgccaaacac atggataatg tgggctgtat cgttctacta gggtccgata acctagtaga
     9481 atggcagttc gaatccatct ttttaaaagg gggagaacac caaggcttta tgtgggaatg
     9541 cccagattac ttcgagttag atgggaaaga ttgccttatt atgtcaccca tgcgttatca
     9601 gcgtgaggga gactcatatc ataacatcaa ctcatcgctt ttgttcacgg gtaaggtaga
     9661 ttggagagaa aaacgtttta tcccagaatc agttcaagaa attgatcatg gccaagactt
     9721 ctatgcgcct caaacattgt tggacgatca aaatcgtcgt atcctgattg cttggatgca
     9781 gacatggggg cgtacccttc caacccatga ccaagaacac aaatgggcat gtgccatgac
     9841 tttacctaga attctaagat tggaagatgg caaactaaga caattccctg ttaaaaaagg
     9901 ccaatatcaa atccaaatag ataaagattg tcattaccac ttaggaaatg atacagatta
     9961 tcttgaattt ggttatgaca gtaatgcgca gcaagtttac attgatcgta gccatcttat
    10021 tcaaaaaatt ctaggtgaag aagaacagga cactagtcga cggtatgtag atattgaagc
    10081 taaagaattg gaagttgttc tagataaaaa ttccatcgag atttttgtca atcaaggtga
    10141 agcaagcttg actgcaactt attacttaac ggtgccagct gagctatcac gaattgatta
    10201 aaaattaagt tatttctcct aaagaaaaag ttctctttct aaaatagtgg aaagaggact
    10261 ttttgtgttt tgggtatata agcttagttt atggtatttg taaaattggt gttggattat
    10321 gatttaagct agttttctaa agaatttgaa aaaaatttta tttaagcaaa aaaaccttgg
    10381 ttccaaggct tttcctgttg tatttatatg ccccctacag ggatcgaacc tgtgacccac
    10441 ggattaagag tccgctgctc tgccagctga gctaaggagg caaagaaaaa agctgtattg
    10501 gtgccgaaac ttcacggttt gtattgaacc cgcgcaatta agcaggtggg caactcgctc
    10561 taactgaagc tgtttccgtg tgagacggcc tacatgctgt tagaagactt ttgtttccct
    10621 aataatacaa aaaatagtcg gtcaacactt aagtgtgaag tcgtacacca cagcgtttct
    10681 atatttatat gataccactt ttttaaaaaa aatcaagagg aaagtgcaat tttttgaaaa
    10741 ggatttcaga tttttcgcaa atggtcgata gcttcctttc tttgagccaa agcccgttca
    10801 tatttaccag tatcttctgc ttggaaatag tgatgattac gaattttttc tggcagatag
    10861 tcttgcttta cccaatttcc aggatagttg tgtggataga gatagtcttg ggcattcccc
    10921 agttccttgc ttccactgta gtgcccatca cgtaggtgtc gcggaatagg caagtgccct
    10981 gatgttttga ggtcagcaag tgccttatcc atagctacat aggctgagtt ggattttgga
    11041 gaaagggcca aatcaatcac gacattggca atgagaatgc gggcttctgg gaacccaatc
    11101 ttctgggcag catccagagc agtcacggta tgaatctggg cctcaggatt ggctaagccg
    11161 atatcttcat aggcgataac agtcaagcga cgagcgagac taggcagatc cccagcctca
    11221 atcaagcggg cagcatagtg gagactggca tccacatctg agccacggat agacttttgc
    11281 agggcagata gaacatcata gtgaccgtct ccatccttgt ccatagtgat gtagcttctc
    11341 tgaagactat tttccatgat gtctaaggtg atgtggcgaa tgccctcgtc attctcaggg
    11401 gtagagagaa cagccaagtc cagtgagtta aaggcagagc gaaggtctcc gtttgtagag
    11461 gttgcgatga aatccagcgc atcctcatct agttctattg gaaaatcaaa accacgttca
    11521 gggttactta gagctatctg cagggcctct ttgacgtctt ggttagacag aggttccaac
    11581 tcgaaaattt gaacacggct acgaatggca ggagtgacag agaagaaagg attttcagtc
    11641 gttgctccaa tcatgatgac cagtccactt tccaagagag gcaagaggaa gtcttgcttg
    11701 gtcttatcta gtcgatgaat ttcgtctagc aataggacga gaccaccaga aaatttagct
    11761 tcttccgaga tttcttgcag tcgcttttta ctatcaactg tcgcattgaa agttcgaaag
    11821 gcatacttgg tcgttccagc gatggcagag gcaatactgg ttttgccgat tcccggaggg
    11881 ccatatagaa tcatggagga caggcggttg gcttccacca tgcggcggat gatttttcca
    11941 ggtccgacca gatgctcctg accgatgacc tggtcgatgg ttttagggcg catgcgaagc
    12001 gcgagattgt ctggcatagc agtcctttct aacgtggatt tgagtagaat gactcatcta
    12061 ctatatctta ctatgtccat tctagcctat tagttgtgat atttcaatgg ttttgtaata
    12121 atcagggagt gagatagaat cttttttact atttaattta atgaggagag gtatcagcat
    12181 gagagatttg attttcctta aagctcaaaa taggatagtt gagcctaaag aagtggaagt
    12241 gctgacttga gaaataatat tgctgaatgt cattgtatga actataatga aaagagaggt
    12301 gataagcaat ggaaatgatg gaccaagtca ggaaattttg atttttacaa aacaaattcg
    12361 tcattggatt cttagtgatc aagttatttc agggaaaaga aaacttttct tccgggaaga
    12421 tactccaaaa gagattttag atttgtacga aaacattaaa tctaaacttg attttgctta
    12481 ccaagaagtt cattctaata atgggttgaa aaaatatgaa aaatagaata attgatgttt
    12541 ttgaagtagt aaatcgcctc cttgtaataa ctgttgaaaa tcctgatttc gaagacttga
    12601 gagttaatca tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    12661 ttgagtacgg taaggcgacg ttgacgtggt ttgaatttga ttttcgaaga gtatcagttt
    12721 gtaaaaattg gagataaaaa atatagagta cgcagtgttc ctatgattca ttcaactccg
    12781 cctcaatctg tcttagatcg agatactttt acaattgact atacagatga tgaattgctc
    12841 gataaagaag cagtttttac tactcattag aaaaataggt ctgaataaat tggcttccct
    12901 tagaaccaca tctaggggct tttatgtata atagaataat aagtatcact cctttacaat
    12961 acgtgtaaca cgtgttataa tggtgttgtc aggaggtaaa agcgctatgc ctatgacaca
    13021 aaaagagatg gttaaactcc ttacggccca tggttggata aagactagag gcggtaaagg
    13081 ctcccatatt aaaatggaga agcaagggga aagacttatc acaatccctc atggtgagct
    13141 gaataagtac actgaaagag ggataagaaa gcaagctggg ttgtaaaatt cagcccctgt
    13201 tttttgatat ggaggtagtg aaatgttagt tacgtatcca gctttatttt attatgacga
    13261 cacagacgga acagaagcga cttattttgt ccatttccca gattttgaat actcagctac
    13321 acaaggagag gggatttctg aggctttggc tatggggtcg gagtggctag ggataactgt
    13381 tgcagatttg atagagagtg atggagagtt acctcagcca tcagatatca atagcttgtc
    13441 tttaattgat aatgatcctt ttaaagatga tgaagatttc gtgtcaacct atgaccttga
    13501 taaatctttt atttctatgg tatctgttga tgtatcagaa tacctaggaa gtcaggaacc
    13561 cataaaaaag actttgacca taccaaaatg ggcagataag ttgggacgag aaatgggact
    13621 taacttttct cagactttga cagacgctat tgcagataag aaagttcaag cctaagatta
    13681 agcgtggtat cgtggtaata gtcaataaaa aagcacgtcc acttgtgcta gttactcgcc
    13741 tattgatttt atagatttat tagccctttc gcgggctttt tatattgatt tttatgagaa
    13801 atgaagaaat cagactttta agaaaatcac tgataccaag ggtttaaatg aggtaatatg
    13861 gtataattag gacataaaat aattttgtgg taagatggta gtatctattt tagcatattt
    13921 ccgagcaatc ggggcgatta aagagtcgca tagaaagagg acaaaatggc aacatacgga
    13981 tttttagatg ttttagagga agagttggac aagaactttc cctttgactt tgagattagc
    14041 tgggacaaac gcaaccatgc ggtagaagtg agttttctat tggaagcgca aaatgctgca
    14101 ggtgtggaga tggtggatga agacggagag gttttatcag atgacattct ttttgaggaa
    14161 gcggtccttt tctacaatcc tgccaagtca acagtcaatg aggaagacta tttgactgtt
    14221 attccttacc tgcctaaaaa aggattttcc cgtgaatttt tagcttattt tgcgcttttc
    14281 cttaaagata ctgctgaggt tgggctagat gtcctcatgg actttttgga agacccagaa
    14341 gcagaggaat ttgtcatgga atggaaccaa gaagtctttg aagaaggaaa agttggcttg
    14401 gaagagggag aattttatcc ttatccaaga tactaggagt tggttggagg tgttatgaag
    14461 aaaattggga cttatttggt ttatgtgcta gcttttgtct ttattatgct agcttttgct
    14521 tgtggaacaa tcgcatttgc agagttgggg tattccgcag ttttagcctt tacttttggt
    14581 tatgccttcg ctcttctaag catgtattta atctttattc ttcatgagct gggtcatgct
    14641 ttttgtggct acttgacagg ctatcggctg gtggcttttg gattaggaca ttttattttg
    14701 accaaaaagt caggcaggtt tcatcttagt agaacagcca ttctgaaaaa tgttggtgct
    14761 caatacattg gtttaaaaga ggatgaaagc gatcaaagaa tcatcctgat gctttcagga
    14821 ggcttgatgg ttcatctcgg cttgatatta ttggcgatag tgtttggatt tttgacaaga
    14881 agctggtatt ttgcagggac ttggattttt cttaatttat ctttcttcct aaataacatt
    14941 ttgccagtcg acatcaccga tggagcaaaa atttgggaat tactacaaca ccctgaaaat
    15001 agcaaatacg cctacctggt attgagacat tctgctcaaa ctttgctggc tcctcaagaa
    15061 tatgatttga aagactttgt tcaagcagtt cctgaggatg cacgagggag ttttgcggat
    15121 ggtgtattag gtatgcaagg tgaagtttcc attttggaag ggaaggaaga agtagctaaa
    15181 cagcagtttc aagcattact tgagaggaca actactccga tgatgcagac agttgcccaa
    15241 ctatccctac ttcatatcgc cttgttggaa ggagattttg agcaagcgga gcaatatgct
    15301 agtattcgac aggtcaaatc gtttctgtct ctcaaactgt ccaatcttca agtgatacaa
    15361 gcttggtatc aatttaaggt aaggaaagat gtggttcaaa ctcacaaggc tatgaagatt
    15421 gctagacaga aaatggatag tagtcgaatg ttgagggacg agaaacgcta ttatgaaaac
    15481 ttgttagcag agctggaaaa ggaaatgtta gaaggaactg aagatggaac tagaaatttc
    15541 tgatttccca ggctgtaaga ttgctttgtt ttgtggggat aagcttttga ctatcttacg
    15601 cgatgataag gcaagcattc cctgggccaa tatgtgggaa ctgccaggtg ggggacgtga
    15661 aggtgatgaa agtccttttg agtgcgcggc gcgtgaagtt tatgaagaac tgggcattca
    15721 tttagatgaa gactgtctgc tttggagcaa gatttatcct agcgtaattt ttaaaggcaa
    15781 gaaatcgctc tttatggttg gtcagctaag acaagaacaa tttgacaata tcatcttcgg
    15841 agatgaagga cagggctata aattgatgcc tattgaggaa tttctcaatt ctaaacaggc
    15901 agtgcctcag ttgcagggaa gattgagaga ttatttggag gaaagtttat gataacactt
    15961 gttcgagcgg gagcagagga tttagaaact attattgcaa ttcagagagc cagctttaag
    16021 gctgtttatg aaaaatacca tgatgaatat gacccttatc tcgaggactg cgaacgaatt
    16081 aagtggaaat tagtcgagcg tcccaatagc tattactact ttgtaaaaga agatgaagaa
    16141 aacatcggat ttttacgagt tcagaccaat gccgagttaa cgaaagcttg gttgggaacg
    16201 gcagcgattt tgcctcagta tcaaggaaaa gggtatggat ctaaaggttt aagcttactg
    16261 gaaaaagaat ttccaaccat cacacaatgg gatttgtgta cggtgttaca ggatgcaggc
    16321 atggttgctt tttacgagaa aaacggctat cgtcaaatcc acattgaggc tgaaaaagaa
    16381 ggcatggata tggtctacat gaaaaaattg atagagaaat agaaaggatg gttcagttaa
    16441 atttctaaac tgaacccgcc ctaaacactg tgccaaaaag ataaacttct cttagacaca
    16501 agcgtcttca gagaatttcc tattttggtt ttgtgtttta cgggcttggt atcttaatga
    16561 tggaaacatg gcaagagtta aaagttacag tgaagcgtga gggggaggag ttggtttcca
    16621 atctcttgat tgagctggga gcgcaaggtg ttgcgattga agacagtctg gactatgtgg
    16681 gaaatgttga ccgctttggc gagattttcc cagaggtgga gcagcaagaa gaaatcgtag
    16741 tgaccgccta ctaccctgac acggtggatg tgacagtggt tgaggcggat ttgcaggctc
    16801 gtctagcaga attgacagat tttatggatt tgggagagtt aaaaataggt acgactgcct
    16861 tggctgagga agactgggca gacaactgga agaaatacta tgagccagct cgtatcactc
    16921 atgatttgac cattgttccc tcttggacag actatgaggc gactgcggga gaaaaaatta
    16981 tcaagctgga tcctggcatg gcttttggta ctggaaccca cccaactacc aagatgagcc
    17041 tttttgcctt ggaacaggtt cttcgtggtg gcgaaacggt gctagatgtg gggactggtt
    17101 caggggttct ctctattgcc agctcgcttc tgggggctaa agaaattttc gcctatgacc
    17161 tggatgatgt ggcggttcgt gtggctcagg aaaatattga gctcaaccct ggcatggaaa
    17221 atatccatgt agcggctgga gatttgctta agggtgtgga aattgaggca gatgtgattg
    17281 tggctaatat cttggcggat atcctcattc atctaataga cgatgcctat cgtttggtca
    17341 aggacgaagg ctacctgatc atgagtggca ttatcaagga taagtgggac atggtgcgtg
    17401 agtcggctga atcggctgga tttttcctcg aaacccacat gattcaaggg gagtggaatg
    17461 cctgtgtctt taagaagacc aaggatattt caggggtgat tggaggctag catgcagcag
    17521 tattttgtaa aaggcagtgc tatctctcct gtcactatcg aggacaagga aatcagtaag
    17581 catatgtttc aggttatgcg cttgaaagaa gaggatgagg ttaccttagt ctttgatgat
    17641 ggcatcaagc gcttggcgcg cgtgctggat atggaaaatc gtcagtttga gttggtccaa
    17701 gaattaaatg acaatgtgga actaccagtc caagtgacca tcgcatctgg atttcccaag
    17761 ggagacaagc tggagttcat cgctcaaaaa gtaaccgaac tgggtgctag ccaaatctgg
    17821 gcctttcctg cagactggtc agttgccaag tgggatggca agaaattggg taaaaaagtt
    17881 gaaaaactag aaaaaattgc ccttggagca gccgagcaaa gcaagcgtaa tattgtacca
    17941 agtattaaac ttttcgagaa aaaagcagat tttctagctc agctggacca gtttgactct
    18001 atcatagtag cctatgaaga atcagctaaa gaaggagaag ccgctgcgct tctgcaagca
    18061 gtcactggtc ttgaaacagg agccaaactg ctctttatct ttggtccaga aggtggtctc
    18121 tcacctgcag aaatcgaaag ttttgaagct aaaggagcag ttttggcagg cctaggtcct
    18181 cgtattttgc gagcagaaac agcaccgctt tacgccttat cagcccttag tgttttagta
    18241 gaattagaga aataagagga agaaaatgga acaaaaacac cgttcagaat ttccagagaa
    18301 ggaactctgg gacttaacag ccctatacca agaccgtgag gatttcttgc gtgcaatcga
    18361 gaaagctcgt gaagacatca accaatttag ccgtgattac aagggcaatc ttcacacttt
    18421 tgaggatttc gagaaggcct ttgcggaatt ggaacagatc tacattcaga tgagccatat
    18481 tggcaactat gcttttatgc ctcagacgac ggactatagc aatgacgaat ttgccaatat
    18541 tgcccaagct gggatggaat ttgaaacaga tgccagcgta gccttgacct tctttgacga
    18601 tgccttggtg gtagcagacg aggaagtctt ggaccgtttg ggtgaattgc ctcacttgac
    18661 ggcagctatt cgtcaggcca aaatcaaaaa agcccactat ctaggggctg atgtggagaa
    18721 ggccttgacc aatctcggtg aagttttcta tagtccgcag gacatttata ctaagatgcg
    18781 agctggggat tttgaaatgg ctgactttga agcccatggc aagacctata aaaacagctt
    18841 tgtcacctat gagaatttct accaaaatca cgaggatgct gaggttcgtg agaaatcctt
    18901 ccgttccttc tcagagggac ttcgtaagca ccaaaatacg gctgcagcag cctatctggc
    18961 tcaggtcaag tctgaaaaac tcttggctga tatgaaggga tacgactctg tctttgatta
    19021 tcttctagct gaacaagaag tggaccgtgt catgtttgac cgccagattg acctcatcat
    19081 gaaggacttt gcaccagtcg ctcagagata cctcaagcat gttgccaagg taaatggtct
    19141 tgaaaagatg acctttgcag attggaaatt ggacttggac agcgccctga atcctgaagt
    19201 gactattgac gatgcctatg atttggtcat gaagtcggta gaacctttgg ggcaagaata
    19261 ttgtcaggaa gttgctcgtt accaagaaga gcgctgggtg gactttgctg ctaacagtgg
    19321 caaggattcc ggtggttatg cggcggaccc atatcgcgta cacccttatg tactcatgag
    19381 ctggacaggc cgtttgagcg atgtctatac cttgattcat gaaatcgggc attctggtca
    19441 atttatcttt tcagacaatc atcaaagcta tttcaacgcc cacatgtcga cctattatgt
    19501 tgaagcaccg tcaaccttca atgaattgct actcagtgat tacttagaga accagtctaa
    19561 tgacccacgt caaaaacgct tcgctctggc tcatcgcttg acagacacct acttccataa
    19621 tttcatcacc cacctcttgg aagccgcctt ccagcgtaag gtgtatacat tgattgaaga
    19681 aggggagacc tttggagcaa gcaagctcaa cagcattatg aaggaagttt tgacagattt
    19741 ttggggcgat gccattgaaa tcgacgacga tgcagctttg acttggatgc gccaagctca
    19801 ctactatatg ggcttgtata gttacactta ctctgctggt cttgtcatct cgacagctgg
    19861 ttaccttcat cttaaaaact cagaaactgg agctgaagac tggctcaatc tcctcaaatc
    19921 aggtggtagc aagacaccac ttgagtcagc catgattatc ggtgctgata tttcaacaga
    19981 caaaccactc cgtgatacca tccaattctt gtctgacaca gttgaccaga ttatcgccta
    20041 cagtgctgag ttgggggagt aaggggaata gaaaaatttt ctagaatgat gtttatgggc
    20101 ttgttaagcg tcattctatt tgtcttagtt gtagctattt tcaaaaatgt cgttgaaggt
    20161 cgtgatgtta aatttgaact tactgtagaa ctggtattga tagttattta cgtcatttta
    20221 tatcagattg tatttaattg agaattcaat attgagtcat ttaagactgc ctttttgaac
    20281 agttgctaga aatgtagagg tattgaccat gtatcaagat ttactaagaa aaatagcaga
    20341 agaaaaacca aattataacc aggaggaaat ccagtggttg cttgatcatt tgggagatcc
    20401 ttctccagaa attcgcgatg accttgtttt tacaagcttt gctagaggga ttcaggaaga
    20461 gctatttaca caggagcaat ttcatttcat tgctgaaggg gtttcatctg atgtaggact
    20521 agataaagag attgataagg taggcctgcc aacactggaa cgttctttta gggcacttgt
    20581 ttatgcaaat ctcttgtctg cagatgctaa ccagcaatcg gttttttatc agggattaca
    20641 atcagaaatt cgtaatgtcc ttttaaatca aggcttgcac tatctttcaa aagaaaagga
    20701 tacaacaggt ttctcaagtc agtatggttg ggttcatgct tttgcacatg gagccgattt
    20761 actgacagag gtggtttgtc atccagactt tcctaaaaac agagttcatg aagtatttga
    20821 tatacttggc caactattta aaagaatgtc gattcgcttt acagatgatg aggattggcg
    20881 tttagcaaga gtgatctatg aacctatttt acaagggaag ttggagcaag aacaagtagc
    20941 ttcttggata aaaactgttg attttccgat agaagaaagg gaggattttt acaaattttc
    21001 caactttaga tcctgtctgg tggaagtcta tgtccaactt gaccagagaa atagtttaca
    21061 agatgacctg aaagaagcta tccagtcttt tcaatactag ggattagcta atagttctat
    21121 gattttcaaa aaatttccaa tcaattttct tgaaaccctt tcctactttt gatagactag
    21181 tatctagttt ttgaaaaaag gagaaagaaa atgaaaaaat ttgttgctga gttaatcggt
    21241 acgttcatgc ttgtgttcgt tgggacagga gctgttgttt ttggaaatgg tcttgatggc
    21301 cttggtcacc ttggaatcgc ctttgccttt ggtttggcaa tcgtggtggc ggcctactca
    21361 atcggaactg tttcaggtgc tcacttgaac ccggctgttt cgattgctat gtttgtaaac
    21421 aaacgtttgt catcttcaga acttgtaaac tacatccttg gtcaggttgt tggagctttc
    21481 atcgcttctg gcgcagtctt cttcctcttg ggtaattcag gtatgtcaac tgctagtctt
    21541 ggtgaaaatg ccttggcaaa cggtgtcact gtctttggtg gtttcttgtt tgaagtcatc
    21601 gcaactttct tgtttgtctt ggttatcatg actgtgactt cagaaagtaa gggcaatggc
    21661 gcgattgctg gtttggtaat cggtttgtca ttgatggcga tgattcttgt cggattgaag
    21721 attactggac tttcagtaaa cccagctcgt agcttggcac cagctgtctt ggtaggcggc
    21781 gcagcccttc aacaagtttg gattttcatc cttgcaccaa tcgctggtgg agttcttgca
    21841 gcccttgttg caaaaaattt ccttggaaca gaagaataat tgaaactcaa aaagccttgc
    21901 tcctcatctt gaggaacagg gctttttcgt at
//
LOCUS       DAVEHY010000037        21628 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVEHY010000037 DAVEHY010000000
VERSION     DAVEHY010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.037"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..551)
                     /locus_tag="VUZ44_001694"
     CDS             complement(<1..551)
                     /locus_tag="VUZ44_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU0320567.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTA"
     gene            793..1464
                     /gene="sdaAB"
                     /locus_tag="VUZ44_001695"
     CDS             793..1464
                     /gene="sdaAB"
                     /locus_tag="VUZ44_001695"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU0320568.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            1473..2345
                     /gene="sdaAA"
                     /locus_tag="VUZ44_001696"
     CDS             1473..2345
                     /gene="sdaAA"
                     /locus_tag="VUZ44_001696"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU0320569.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            2367..2999
                     /locus_tag="VUZ44_001697"
     CDS             2367..2999
                     /locus_tag="VUZ44_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU0320570.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            3025..3123
                     /locus_tag="VUZ44_001698"
                     /pseudo
     CDS             3025..3123
                     /locus_tag="VUZ44_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3485..5335)
                     /locus_tag="VUZ44_001699"
     CDS             complement(3485..5335)
                     /locus_tag="VUZ44_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU0320571.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFHTLSGDELKQAIIAFANQTTHIE"
     gene            complement(5377..6534)
                     /locus_tag="VUZ44_001700"
     CDS             complement(5377..6534)
                     /locus_tag="VUZ44_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0320572.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQCEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLYQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            6592..7758
                     /locus_tag="VUZ44_001701"
     CDS             6592..7758
                     /locus_tag="VUZ44_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU0320573.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            7897..8223
                     /locus_tag="VUZ44_001702"
     CDS             7897..8223
                     /locus_tag="VUZ44_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU0320574.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            8210..8803
                     /locus_tag="VUZ44_001703"
     CDS             8210..8803
                     /locus_tag="VUZ44_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU0320575.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            8796..9707
                     /locus_tag="VUZ44_001704"
     CDS             8796..9707
                     /locus_tag="VUZ44_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU0320576.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            9770..10834
                     /locus_tag="VUZ44_001705"
     CDS             9770..10834
                     /locus_tag="VUZ44_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320577.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11012..11872)
                     /locus_tag="VUZ44_001706"
     CDS             complement(11012..11872)
                     /locus_tag="VUZ44_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU0320578.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEMQPILD
                     KDFKTLAQEK"
     gene            complement(12147..13133)
                     /locus_tag="VUZ44_001707"
     CDS             complement(12147..13133)
                     /locus_tag="VUZ44_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU0320579.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(13405..14880)
                     /locus_tag="VUZ44_001708"
     CDS             complement(13405..14880)
                     /locus_tag="VUZ44_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU0320580.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(15138..16061)
                     /locus_tag="VUZ44_001709"
     CDS             complement(15138..16061)
                     /locus_tag="VUZ44_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU0320581.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(16075..17004)
                     /locus_tag="VUZ44_001710"
     CDS             complement(16075..17004)
                     /locus_tag="VUZ44_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU0320582.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(17323..17544)
                     /locus_tag="VUZ44_001711"
     CDS             complement(17323..17544)
                     /locus_tag="VUZ44_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320583.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSRKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(17498..17758)
                     /locus_tag="VUZ44_001712"
     CDS             complement(17498..17758)
                     /locus_tag="VUZ44_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320584.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(18185..18340)
                     /locus_tag="VUZ44_001713"
                     /pseudo
     CDS             complement(18185..18340)
                     /locus_tag="VUZ44_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(18525..19136)
                     /gene="rpsD"
                     /locus_tag="VUZ44_001714"
     CDS             complement(18525..19136)
                     /gene="rpsD"
                     /locus_tag="VUZ44_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU0320585.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(19331..20383)
                     /locus_tag="VUZ44_001715"
     CDS             complement(19331..20383)
                     /locus_tag="VUZ44_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU0320586.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(20380..21078)
                     /locus_tag="VUZ44_001716"
     CDS             complement(20380..21078)
                     /locus_tag="VUZ44_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320587.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(21245..>21628)
                     /locus_tag="VUZ44_001717"
     CDS             complement(21245..>21628)
                     /locus_tag="VUZ44_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU0320588.1"
                     /translation="GKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMN
                     HNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMA
                     SIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT         6359 a         4670 c         4088 g         6511 t
ORIGIN      
        1 gctgtccatg aaccgtaacg tcctgcaacg taggcatctg ctacacgttc ttggttttca
       61 gctgagtagt caccgttcag gtatgaatct gttaattggt aacgtccgat ataacgtcca
      121 tttgtagctg tatagctacc acctgattct ttttgagcga tccattcttt ggcttctgct
      181 tcagatccgc ttacagttga aacaactgtt tcacttacta ctggagtttc tgccactgga
      241 gctgaaacag tttcatcttg agcggctggt gccgcataag tagctggcgc tggtgttgca
      301 acaggcgcta cagggccatc gataaccaac tcttgaccaa cataaatcaa atgaatgtta
      361 tcaatgtggt tgttttctgc caatttttca actgttgtgt tgtgagtttc agcgatttct
      421 gaaagtgtat caccttcttt aacagtgtaa gttgatgatt cttgagcaga tacaaatgat
      481 ggagcaaata ctgcaaacaa ggcagctact cctgcaagag ttgctttaat ctttttagtt
      541 attgatttca tattcgaaaa ttctccttct ttctatagtt ctatcatacc ctttaaatat
      601 taccgtttct tgacactttt atgtagaaat attacaaaat tattttttat ttccctaaat
      661 aaggtgtttt ttgtcataaa agatactatt tttatgctat ttgaggtatt agaaaggttt
      721 tcatccacaa ttaaagccaa gcccctcatt ctttgatata atagagataa gaatttttat
      781 aaggggaaac tgatgaaatc acttcgtttt caatctgtct ttgatatcat cggaccagtt
      841 atgattggcc catctagtag ccataccgct ggtgctgttc gtattgggaa gattgtctct
      901 tccatttttg atgatactcc gacagaagtt gaattccaac tttttaactc atttgccaag
      961 acctatcgtg gtcacggaac agacctagcc cttgttgcag gtattttagg aatggataca
     1021 gatgatcctg aaattccaaa tagtctggaa attgcccaca agcgtggtat caagattgtc
     1081 tggaccattc agaaagacag caatgcccct caccctaaca ccactaaaat tactgttaaa
     1141 aatgcccaca agaccatcag cgtgactggt atttctatcg gtggaggaaa tattcaggta
     1201 accgaactca atggttttgc cgtctctctc aatatgaata caccgactat catcatcgtt
     1261 catcaagata ttccaggtat gattgccctt gttacagagg cgctttcccg ctatggtatc
     1321 aatatcgccc agatgaatgt cactcgtgaa aaagctggtg aaaaagccat tatgattatc
     1381 gaagttgaca gtcgcaactg tgatgaggct atcgaagaaa ttcgaaaaat ccctcatctc
     1441 cacaatgtca atttctttaa ataggaggaa gcatgtttta ttctatcaaa gaattggtcg
     1501 agcaagcaga tctggacttt caaggaaatg tcgcagaact catgattaca acagagtttg
     1561 aattgaccgg tcgcgaacgt gaagaagtct tccttctcat ggaacgcaat ctggaagtta
     1621 tgaaagcctc tgtccaactt ggcctcaatg aaaataaatc tcgtagtggc ctgacaggtg
     1681 gagatgctgc caaattggat cactacatcg aaaacggaaa aactctgtca gattatacga
     1741 ttctctcggc tgcccgaaat gccatcgcag tcaatgaaca caatgccaaa atgggcttgg
     1801 tctgtgccac tccaaccgct ggaagtgctg gctgtctgcc atccgttctc actgctgcta
     1861 ttgaaaaatt agacctcagc cacgagcaac aattggattt cctctttgct gctggtgcct
     1921 ttggactagt catcgcaaac aatgcctcca tctcaggtgc tgagggtggg tgtcaagctg
     1981 aagttggttc agcctctgct atgagtgctg ccgccttgac tctggctgca ggtggaacac
     2041 cttatcaggc cagtcaagct attgcctttg tcattaaaaa tatgctaggc ctcatctgtg
     2101 accctgttgc aggtttggtc gaagttccct gtgtcaaacg taatgccatg ggagctagct
     2161 ttgctttcat cgcagcagac atggccttgg caggtatcga atctaaaatc cctgtggatg
     2221 aagtgatcga tgccatgtac caagtaggag caagcatgcc aactgccttt cgtgaaacag
     2281 ctgaaggtgg actcgctacc acccctactg gtcgtcgcct ccaaaaagaa attttcggag
     2341 aataagctta tcaaatagga gaaaccatga cctctatcac agcgattttt ttcgatttgg
     2401 atggaaccct cgttgatagt tctatcggga ttcacaatgc ctttacctat acctttaaag
     2461 agctgggggt gcctagccct gatgccaaaa ctattcgtgg ttttatggga ccacctctcg
     2521 aaagtagttt tgcgacctgc ctgtccaaag accaaatttc tgaagccgtg cagatatatc
     2581 gttcttacta taaggcaaaa ggcatctatg aagctcaact ctttcctcag attatagact
     2641 tgcttgagga gttatcgagc agttatccac tctacatcac cacgacaaag gatacatcta
     2701 ctgctcaaga catggcaaaa aacttggaaa tccatcattt ctttgatggc atttatggtt
     2761 ctagccctga agcaccccat aaggcagatg tcattcacca agccttgcag acacatcaac
     2821 tagcaccaga acaagccatc atcatcggag ataccaagtt tgatatgctg ggagctcgag
     2881 aaacaggtat tcagaaattg gccatcactt ggggatttgg agagcaagca gatctactaa
     2941 actatcaacc tgattatatc gctcacaaac ccttagaagt tttggcgtat tttcaatagc
     3001 atagactggg taacaattcc atttcagaag aaaatgaagt aatactcaat gaaaatcaaa
     3061 gagcaaacta ggaaactagc tgcgggctgc tcaaaacact gttttaaggt tgtagatgga
     3121 actgacgaag tcagctcaaa acactgtttt aaggttgtgg atggaactga cgaagtcagc
     3181 tcaaaacact gttttaaggt tgtggatgga actgacgaag tcagctcaaa acactgtttt
     3241 gaggttgtgg atagaactga cgaagtcagc tcaaaacact gttttaaggt tgcagataga
     3301 actgacgaag tcagctcaaa acactgtttt aaggttgcag atagaactga cgaagtcagt
     3361 aacatataca tacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtataa
     3421 gtctctacat aataaaacgc atattaccaa ggttgtgtaa cttgatacta tgcgtttttc
     3481 ttttttattc aatgtgggtt gtttgattag caaaggcgat aatagcttgc ttcaactcat
     3541 ctccactgag agtgtggaac tctccaatct tttgattgat ggattctaaa ggcatgacat
     3601 taaccttacc aacgaaaatc ttatccataa cttgattatc aacgagttcg gttgatacca
     3661 agagttcttc gtagagtttt tcacctgggc ggattccaac ttcaacgatt ggaatttcac
     3721 tttcagtgtg gccacttaga agcaccatct tcttggccaa gtcataaatc ttgactggtt
     3781 tgcccatatc aaggataaag acttccccat ctttggcata agcaccagca tggataacca
     3841 gacggctagc ttctggaatg gtcataaagt aacgggtcat gcggaagtct gtcaccgtta
     3901 caggcccacc ttcagcaatc tgacgttcaa agactggaat gacactacca cggctaccaa
     3961 gaacattccc aaaacgaact gcacagtagg ttgattggct acgttggtta aagccagtga
     4021 caatcaactc cgccacgcgc ttggttgctc ccataacatt tggtggatta actgccttat
     4081 ctgtcgaaat cataaccatc ttagacactt tagcttcatc aacagcctta gcaacattgt
     4141 aagttccacg gatattgttt ttgaaggctt cttttggatt gcgctccatc ataggaacat
     4201 gcttgtgggc tgccgcatga taaacaatag caggtttgta ctgctcaaag acttgcaaca
     4261 aacgatcata gtcttgaatg tccgcaatca caggtacata atcaatccct tggaacttac
     4321 gaatcaattc atgataaaca aggtagattg agttttcccc atgaccgagc aagacaatgc
     4381 gttcaggatt gaagcgacta acttgacgac agatttcaga accgattgaa cctccagctc
     4441 ctgtgactaa gatggtctta cctgtcagtt ctgcacccag acgcgattcg tcaagacgga
     4501 tttcctgacg acccaaaagg tccgtaatat caattttttg gaagccagta cctgcttggt
     4561 gaaggccctg aacaacagtt tcaaccttag gcatcttgta acatttgaca cccagcttat
     4621 tacacatctg caagatacgc tcatattctg acggatccag cgacggaatc gcaacgatga
     4681 cacgctcgat ttgatggcgt ttggctaatt caggcagatt gtcataagag cccaaaacag
     4741 gaataccacc aagtttttga ccctttttct tagaatcctt atccaaaata ccgaccagtt
     4801 ctaattcact ggttggatgt tggtaactat ccataaaaag agccccacca tcaccggcac
     4861 caatcaagaa ggtccgacgg tgttctccat caccactacc ttttttgcgt ctggagtaga
     4921 ttaactgcca agtaatccgt ggcaataaaa tcaagaaggt actcaacaag ataaagagaa
     4981 tgataaaacg gatggagaag agtggcaaga aggcataaca gatactatat gacaagacac
     5041 tgctagcagt cacaccaaaa aagattttca tgaaatccgt aatcttgctg taacgactaa
     5101 tgctcgcgtt caacccccaa aaaccaatca tcaattgata gaacaggaag gccaaactcg
     5161 tatagataat gtagtcaaca ggtgctggat taatcagccc ataaaataaa atataagata
     5221 caattatgga aaccaccata ctgaaaatat caaatattcc ccagaaaacc tgcttttgtt
     5281 gtttatttaa aatttccacc agatcaatca cataatctgt tagtttttta ttcatagaaa
     5341 tctactcctc cttaaaagag ttttactata ttgttattat agcatatttt tatttatttg
     5401 gcttatttta tccaaataaa ttattgttct cttgtactcc ttcttccatt taaatcctct
     5461 aattaaacct acaatcgtcc caaagccata agcaaagtga atggaaaata aaagaaaggg
     5521 catcacaatt agaaatccat ttttatgttt taataaagtc agcaaagtga gtagtgacaa
     5581 aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg gtaacaatgc
     5641 tagactaaac acaagactca aaacaaataa acaaggaaca tagtgaaata atgataaaca
     5701 cttaaactga acatgacttg tcaagccaat ccacaaacca tttgaatact tttgatacag
     5761 cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc tatagcgaat
     5821 tttataacca tgttctcgaa ttctataatg aatatcatta tcttcagttc ggccaagttg
     5881 ctcatttact aaaccaacct tctggaaaac ctctcgttta tacatcccat gaaaaataga
     5941 agaaacatat ctatcttcgg aactatttcg ataattggca atgctactgc caaacatatt
     6001 ttcctcaaca agatgcaagg tctctgccca ttttcctttt ccttcgacaa tcgtcggtct
     6061 aggcccccca cagacaaatt cacattgttg aataatagcc acattgttca ttacaaaagt
     6121 ctcagtaact tttgaatgag catcaatttt taaaataagg tcccctacag aatgtttaac
     6181 tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc taattgagtt
     6241 aaactctgta tcttccttta taaattgctg aatgatagct gtggtcccat ctgtggacat
     6301 agcatttata aatagaattt caatattctc tttaggataa gtttgatttt ttaagtcttc
     6361 aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg atacgagaag
     6421 actttcaaca ttttgagtca ctactactct cctgaatttt tccttccacc attctatcat
     6481 aattttcaag actttcccat ttttatcttg aaagccagaa accttacttg acattatagt
     6541 gaaaaagcct taaaataagc tgttattaaa atcagctaga agaggtatta tatgaaaaag
     6601 caatcactct tttttgttcc aggtattatc ctgattggtg tttccttgcg aactcctttc
     6661 actgttttac ccattatttt gggaaatatt tcgcaaggtc tggaggtaga agttagttcg
     6721 cttggtgtct tgaccagcct gcctctcctt atgtttaccc tcttttcacc attttctacc
     6781 caactggctc agaaaatcgg cttggagcat ctcttcacct acagcctctt cttcttgacc
     6841 atcggctcac tcattcgact aatcaatctg cccctgctct atctaggaac cttgatggtt
     6901 ggggcaagtg tcgcagtcat caatgtcctg cttcctagtc ttatccaagc caatcaacca
     6961 aagaaaattg gttttctgac caccttatat gtaacgtcta tggggattgc aacggctctg
     7021 gcttcctatc tagctgtgcc cattacacaa gccagttctt ggaaaggact tatcctcctc
     7081 ctcacgttac tctgtctagc aacttttttg gtctggctcc caaatcaccg ctataatcat
     7141 agactagctc cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa taaacaggtt
     7201 tgggcaatta ttatcttttc aggttttcaa tccttgatct tttacaccgc catgacctgg
     7261 ttacctacca tgtctatcca tgcaggtcta tccagtcacg aagctggctt gctgacttct
     7321 atcttatctc tgattagcat tcctttttca atgaccatcc caagcctgac aaccagttta
     7381 tctactcgca accgtcagct catgctcact ctggtttcac tagctggtgt ggtcggcatt
     7441 tccatgctct ttttcccaat caataatttc atttactggc ttgccatcca tctcctcatc
     7501 ggaaccgcaa ccagcgccct cttcccttat ctcatggtca acttttcact caagacaagc
     7561 gcccctgaaa agacagccca attgtccggc ctatctcaaa caggaggcta tatcctagca
     7621 gcctttgggc caaccctctt tggttacagt tttgacctat tccactcttg ggtaccagct
     7681 gtagctgccc tcttgctcat cgatatcctg atgactgtgg ccctctttac agtggacaga
     7741 gcggataaga tcctttaaac ttctagtttt agctagaagt tttttatata taaaaatttt
     7801 acacatttct cttgacaggg ctttctttta gatgtacaat gtatgtgtag aaaaattata
     7861 tataaaaatc ttacacatta gaaaaggagg tttcccatgt actttccaac atcctctgcc
     7921 ttgattgaat ttctcatctt ggctgtactg gagcagggtg attcttatgg ttatgagatt
     7981 agccaaacca ttaagctgat cgctaatatc aaagaatcca cactctatcc cattctcaaa
     8041 aaattggaag gcaatagctt tctgacaacc tattctagag agttccaagg tcgcatgcgc
     8101 aaatactact ccttgacaaa cggtggtata gagcagctct tgaccctaaa agatgaatgg
     8161 acactctata cagacaccat caatggcatc atagaaggga gtatccgcca tgacaagaac
     8221 tgaatacctg actcagctag aactctatct caagaaacta cctgaagctg accgtatcga
     8281 agccatggac tatttcagag agctctttga cgatgctgga gtcgaaggag aagaagaact
     8341 catcgctagt ttgggaactc ccaaagaagt ggcccacgaa gttctatcca atcttctcga
     8401 taaaaaaatc aatgaagcac ccgctcaaaa aaataaccga caaattttac atatcgcctt
     8461 gttagccctc cttgcagcac ctatcggcat tcctctggga atcgccatcc tcgtgaccct
     8521 gttcgcaatc cttgtagccg ctttgactgt cattctggct ttctttgcag tttccatact
     8581 gggtatcatc ggcggattcc tatttttagt tgaaagtttc actgtcctcg cccaagccaa
     8641 atcagccttt atcttgattt ttggttctgg tttactggct atcggtgctt cttcgctagt
     8701 tttacttggc atttcctatg tagctcgctt cttcggtcta ctcattgttc gtctggtaca
     8761 atttgttctt aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca aaaggatttc
     8821 tcatctttgg tgtggtgact accgttatcg gctttattct gctttttgta ggtatccaat
     8881 ctgacgggat taagagccta ctttccatgt ccaaagaacc tgtctatgat agccgtacgg
     8941 aaaagctaac ctttggcaag gaagtcgaaa acctagaaat tactctccac caacacacgc
     9001 tcaccatcac agactctttc gatgatcaaa tccacatttc ttaccatcca tctctttctg
     9061 ctcaccatga tcttatcacc aatcagaacg atagaactct gagtctcact gataagaaac
     9121 tgtctgaaac tccgtttctc tcttctggaa ttggtgggat tcttcatatc gcaagtagct
     9181 actctagtcg ttttgaagaa gttattctcc gactaccaaa agggagaact ctaaaaggga
     9241 tcaacatctc agccaatcgc ggacaaacca ccatcataaa tgctagcctt gaaaatgcga
     9301 ccctcaatac aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa aacagtaaac
     9361 tcacaacgcc caatatcgtt aatatctttg atacagttct tacagatagt cagctagagt
     9421 caacagagaa tcacttccac gctgaaaata tccaagtcca tggtaaggtt gaactgactg
     9481 ccaaagatta tctcagaatc atcctagacc agaaagaaag ccaacgaatt aactgggaca
     9541 tctcaagcaa ctatggttct atcttccaat tcacaagaga aaagcctgaa tcaagaggta
     9601 cggaattaag caacccttac aaaactgaaa aaaccgatgt caaggatcaa ctcattgcga
     9661 gatctgatga taatattgat ctaatatcca caccaagcag acgttgacaa aaacgcttac
     9721 atctgctact atggaagcat atttatctaa ctaaaaagga ggttctacca tgaaacaaga
     9781 atggtttgaa agtaatgatt ttgtaaaaac aacaagcaag aacaagcctg aagagcaagc
     9841 tcaagaggtt gcagacaagg ctgaagaaac gatagccgat ctcgatacac caattggaaa
     9901 aaatactcaa gtagaggagg aagtctctca agctgaagtc gaactggaaa gccagcaaga
     9961 agagaaaatt gaaactcctg aaggcggtga agcgagaaca gaaatagaag aaaagaaggc
    10021 atctaattct actgaagaag agccagacct ttctaaagaa acagaaaaag tcactatagc
    10081 tgaagagagc caagaagctc ttcctcagca aaaagcaacc acgaaagagc cacttcttat
    10141 cagtaaatct ttagaaagtc cttatatccc cgaccaagct ccaaaatcta gggataaatg
    10201 gaaagagcaa gtgcttgatt tttggtcttg gctagtggaa gcgatcaaat ctcctacaag
    10261 taagttggaa acaagtatca cacacagtta cacagccttt ctcttgctca ttctgttttc
    10321 tgcatcttcc tttttcttta gtatctatca catcaaacat gcttactatg gacatatagc
    10381 aagcattaac agtcgcttcc ctgagcagct agctccttta actctttttt ctatcatctc
    10441 tatcctagta gcgacaacac tcttcttctt ttcattcctc ttgggtagtt tcgttgtgag
    10501 acgatttatc caccaggaaa aggactggac gctagacaag gttctccaac aatatagtca
    10561 actcttggca attccaatct tcctcactgc tattgctagt ttctttgctt tctttgatag
    10621 cctacgattt acagccctct tgtgtgtgat tagcattgga atcattctgc ttgccagtct
    10681 ccatatcatt acaagaccaa gtcaagcaag tgaaaccgac tccttctatc aattattctt
    10741 gtctgtcctt gtgaacggag ttattatcct cctcttcttt gtagctgaag tggcactgat
    10801 tggagattat cttcgtatct tggcctttct ttaaacttca tactcttcga aaatcaaatt
    10861 caaaccacgt cagcttcgcc ttaccgtact caagtacagc ctgcggctag cttcctagtt
    10921 tgctctttga ttttcattga gtagcaatcc tgtcatcctt ggcaggattt tttctatgtc
    10981 aaaaaagcaa gtcgattgac ctgcttctgc tttacttttc ttgtgctaat gttttaaaat
    11041 ctttgtctaa tatgggttgc atttctattt gattggcgtc tagttggtgg taaaaagatg
    11101 ggggtaatac ctctaagaat tttgcatagt ccaagcgggc aatggcttca tagtcttctg
    11161 gtttagagcc gtctcctgtg atttgaacca agtcaatctc ccactggact tccttatcca
    11221 ccaattgctc aatataggct gcaggaacaa acggttctct cggtaaaact gtcttgactc
    11281 cttgagctag atggtaaacg ccatgcactt ttccttctcc atcctgatag aaggaaactc
    11341 tcgcaaagta ggcatctgtc tcttgaaccg cacgcacacg cgcttcaaac tgagccaagc
    11401 catctgcctc taaaaagctt ttcaagttct cacgactaaa gaaaatagga ttaaaaattc
    11461 cttggcaaat cgtaaaacga gctacagggt ctgctagata ggcttgaata cttgcttgga
    11521 aataagcttc aaaatcaaaa ccatctagcc cttcaatatc agtccctgta taagcaagca
    11581 aagcatctaa aaatgacttg ataatctgcc agtctgtctt tgttagtagg tcaggaagat
    11641 cgacacggta agccttttga ccatcagcat aactgacctt aaaaagaaat tgtgattgcc
    11701 ccactatcgc acactcaata tactcgagac gattaagagg ctgacggaga tagactacat
    11761 catagctatg tgactccaaa ccgtctagca aggccaagat cgacttggca ttcaaaatct
    11821 cttgttctcc taaaatgctc tgtttatttg gaataaaaaa tgttttcgcc ataactggac
    11881 tcctttgaaa tcgtttacat acagtatacc ttatttttct gaaagataca aaaacaaact
    11941 ttatattctt cgaaaatctc ttcaaaccgc gtcagcttcg ccttgccgta gatatatgta
    12001 actgacttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcatc ctgcagctag
    12061 cttcctagtt tgctctttga ttttcattga gtattagatt tttgagtaca aagcatagaa
    12121 aaacagcccc tgaggactgt ttgatcttat acagtagctg cctgatccaa gctttcaccg
    12181 atagcggcta ggcgctcaat cacttcagct tgtgtcaatt cattttttga aacatagcgg
    12241 ttacgtgggt gaacacggca ctcgtgtgag catccacgaa ggtacttgtc ttcattttct
    12301 tctgatgtca agatacgacg gttacagaag ggatttccac agttgacata acgttcacat
    12361 ggtgttccat caaaccagtc tttccctacg atggttgggt tgacatggtt gacatcaacg
    12421 gcaatacgct cgtcaaagac gtacattttc ccatcccaaa gctcaccttg aacttctggg
    12481 tctttaccgt aagttgcgat tcctccgtgc aattggccga catctttgta gccttcacgg
    12541 accatccagc ctgagaattt ctcacagcga acgccacctg tacagtaaac cacgacacgc
    12601 ttgtccatga atttttcctt gttatcacgg acccattgtg gtaactcacg gaagttgcga
    12661 atatctgggc gaatagcccc acggaaatgt cctaggtcgt actcataatc gttacgtgtg
    12721 tcaaggacaa cggtatcttt atcaagaagc gcttctttga actcttttgg agacaagtaa
    12781 gcacctgttg tttcaagtgg gttgatgtca ttgtcaaagt cgttgtcttc caaaccaagg
    12841 tggacaattt ctttcttgta gcgaacaaac atcttcttga aggcttgttc attttcttcg
    12901 tcaatcttga accagagttc ttccattcct ggaaggctgt gaacgtagtc catgtatttt
    12961 tgagttgttt catagtcacc tgaaactgtt ccgttaattc cctcgtcagc gactaggata
    13021 cggcctttaa ggccgattga tttacagaaa gccaagtggt ctgcagcaaa ttgctctgca
    13081 ttttcaattg gagtataaag gtagtaaagt aagacacgaa tatcttttgc cataagattt
    13141 gttctctttt ctattcttaa attttctaaa ttttttattt atctacacta gtatacctgc
    13201 ttgagaaaac gaatgcaatt tatttgactg gaaattgtag agggttctcg aaatttcctg
    13261 aatggttaaa ataaggacaa gagaaaacat ggatatctat atccttgtgc caaaaaaacc
    13321 actgccctcc ccagaccaac ctgaggaaag cagtgattct tattttagga gttaggaatg
    13381 aatacacgaa atcaatttag ctgattattt tttgtttttc aagaattcat cgtattgttt
    13441 ttgcatttcg ttcaatactt tttcgtaggc accttcagat ttcaattttt ccatcaattc
    13501 tggaatcgct ttatctgggt ctacagtacc agtgttgata gctgtatcaa attgttgcat
    13561 tgtgttagca atagctgaga tttcagattt cacattgtca gtattgaaga taaatccaag
    13621 cgctggagat tctttagctt ctgccaattc tttcttagaa ttttcgattt gttggtctgt
    13681 aacgttttcg ttgatgtaaa ggatccagtt gttaccagtg ttccatccac ccatgtgagt
    13741 gtttcctttg tagccatcaa gaacgcgaac acggttttct ttaccttcaa ttttttccca
    13801 gttcttgcct tctggaccgt aaacaagacc gttcaagagt tctgggttcg tattcaagag
    13861 gttcaagatt tccattgatt tttctttgtt cttagagttg tttgagatga caaagttagc
    13921 aacttgtgtt gtttggtttt tcttgatgaa gttagtaatt ggtttgattt ggatatcttt
    13981 gttggcaaca cgtgaaagca agctgttacc gtagtcagct ggtcctactg tttcttcacg
    14041 aacgaaccaa gtatcttgtt gaaggtcaaa ggaagtatcg cttgttgcga cgtcttttgg
    14101 aatgtagcca gcttcataga atttgtgaag agtcttcaag tgttctttga aacgaggcac
    14161 ttcgtaacgg tttacaactt tagtagtatc gccttcaagg tcgataacga atggaagacc
    14221 gtttgctact gggtagtcaa agttatcaga tgggatgaaa actttaccaa tagcaaatgg
    14281 tactacgtct ggagcttttt ctttgatttg tttcaagact ggctcaagag tttcgtaaga
    14341 agtaacacct gaaatatcga taccatattt ggcaaggaga gttccgttga aggcaaagtt
    14401 ttgagatgat gcaacgttgg ctgcaactgg aacagcgtaa attttaccgt ttacagtatt
    14461 acccttgata taagctgggt caagtgcctt gtaaaggtct ttaccttctt ttttgtacaa
    14521 ttctgtcaag tcagcataag cacctttttg agcatttaca atatagttat ctgcaaaggc
    14581 gatatcatag ttttcaccag atgatgtgat aactgacatt ttcttaccat agtcacccca
    14641 gccaaggtat tggatatcca atttagcacc aactttttct tcgatgattt tgttggcatt
    14701 tgctaacaat tcatccaagt tatctggttt gtcaccgatt tggtacattt tgataacagg
    14761 tttgtcacct gaatcagcag cttttttgct gttacctgtc aaatttccac aagcagcaag
    14821 acctgcagcc aaagcgacta cactagcaga tgcaaaagca tattttttcc agtttttcat
    14881 gataaaaact ccttttttta tttttaaact tataaacaat gtaatgatct tatactcaat
    14941 gaaaatcaaa gagcaaacta gaaaactagc cgcaggctgc tcaaagcact gctttgaggt
    15001 tgtagataag actgacgaag tcagttacat atatctacgg caaggcgacg ttgacgcggt
    15061 ttgaatttga ttttcgaaga gtattaactt cacacaaggg aagttgggaa ctgagaaatg
    15121 ttctttttca ataagcacta ttctttcaca ccaccgatag tcaaaccttt tacaaagtag
    15181 cgttggaaga atggatataa aatcgcgatt ggaagggttg caaccacaac catggccata
    15241 cgacctgttt ctttcggtag agcaactccc agttgaccag tcaagccgac cgctttggca
    15301 atgtagtcca tattttgttg aatttgcatg agcaaatatt gcaatggata caagttgtca
    15361 ctcttgatgt aaagaagggc gttgaaccag tcattccaga aaccaagagc tgtcaaaagc
    15421 gtgatggttg cgatacctgg tagtgacaat ggcaaacaga tttggaagaa aatccgggcc
    15481 tcactggcac catcgatacg agccgattcg agaatggctt ctggaatggt cttcttgaag
    15541 aaggaacgca tcaagatgat gttaaagggg gagagaagca ttggcacaat caaggcccaa
    15601 acagtgtcac caagctgaag tacacgggtc accatgatat aacctggtac caaaccagcg
    15661 ttgaacaaca tactgagaag gacgaagatg gtaaaaaatc tgcgatactt aaaggttgtc
    15721 cgtgaaatag cgtaggcata ggttgttgtg ataaagacat ttgtcaatgt cccaactacg
    15781 gttacaaaga cagagatgaa gagggcttgt aggattttat ccttaaactg tgccaaaaac
    15841 tcaaaaccgt ctaagccaaa ttgggatggg aagaagctat agccgtattg gaggaggctt
    15901 ttctcgtctg tcactgaaat aatgataacg aatacaaaag gtaggataca agagagggca
    15961 atcaaacccg aaatgatact gaagaagata tctgctttct tactgaagga gtgaatgccg
    16021 acattatcaa ttttttcttt tttaattttc ttttttgcca tattctcctc ctttctagaa
    16081 caaagctgag tttggatcga ctcgtcttgc aagcaagttt gataggataa ccagaatcaa
    16141 accaacaacg gattggtaaa gaccggctgc tgcagccata ccgatatctg ctgtctgagt
    16201 caaaccatta aaaacatata cgtccaaaac gttggttaca ttgtaaagct gaccagcatt
    16261 gtgtgggatt tgatagaaga gaccgaagtc tgcgcggaag atatttccga ctgcaaggat
    16321 ggtcaataca gttacaagcg gagtcaactg aggaatggtt acgttgcgaa tacgttgcca
    16381 cttgctagct ccgtccactg tcgctgcttc gtagtaggtt ggatcaattc ccatgatcgt
    16441 cgcatagtac atgacactgc tatatccaaa gcctttccaa atacctagga aaagtaggag
    16501 atagggccag atgcccaggt cagcgtagaa attgacttct ttgagaccaa gactttccaa
    16561 tagatgattg aacacccctt tatcaatatt taggaaggca tctgtaaaga aactaatgat
    16621 aacccaagac aagaagtaag ggaacaacat agaagtttga aaaatcttca ccattctctt
    16681 agaacggagc tcgctgagga taatggcaat ccctacagat acaactaaac ctagaaagat
    16741 aaagccaaga ttgtagagga cagtatttcg tgtgataata aaggcgtctc ttgaactaaa
    16801 taagaatctg aaattatcga gtccgaccca tttactattt atgatactat ctatgaaacc
    16861 attactggtc atgtggtagt ctttgaaggc aaccacgttc ccaaatactg gaatgtaaaa
    16921 gaatagaatc aaccagagtg cccctggcaa aaccatcaag agaaagatcc agttgtctct
    16981 caatgttttt gaaaactttt tcataatttc ctcccttttt attttgatat ccatctaaaa
    17041 attctttttt agacttttga taacgattac attattagta tactcctatt tgcaggttag
    17101 gttaaactcc taattataga aaaaactcca caaattatgt agcagattta aaactttatc
    17161 accactatca aacaaatgtc ctaaatcaat tgtttatttt atctctatta gcccagtgat
    17221 ggcgtcactc tgttataagc atccaacaac ggggtatact gaaaaatctc cagactaggg
    17281 aactcagaga tagttcctaa tctggagatt tttaatatgt tattaggcgt ttgctttcaa
    17341 cttagcaata acctctttaa gattatcaat cacctctgct tcagtatgct cagagccttt
    17401 ttcatctgcc aagaacaaaa ctgctttttg aagttctttt cgagagtttt caaggacatc
    17461 cttatctact gtttcaaggt ttgagtcttt aagaagttta cttaattcct tggctaattt
    17521 cttgagtttg atttgcagac tcatcttctc ctgctgtttc tttgcccgct gtttgtcctc
    17581 catccttagt tgctgactgg ctttccttaa tggactctag ggaagcaatg gcatctttga
    17641 ctgtttgcaa gatatcacgt aaaccttgct ctgtcaaact atcatctgca agagctttct
    17701 tagcctctgc caaaaccaga cgtgctgaat ctgtggtagg attcgataca cctgtcaatg
    17761 atctcaaaag attttctaag gtttgagtct gcttactaat actagactaa aatcaaaaag
    17821 cattacataa cagtgatatg aaatcaacta aagaagaaat ccaaatcatc aaaacacttt
    17881 taaaagactc tcgtacagct aaatatcata aacgccttca aatcgttcta tagtaaaatg
    17941 aaacaagaac aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
    18001 gtagatgtgt actattctag tttcaatcca ttatatttcg tctgatgggc aaatcttaat
    18061 aaagagatta tagagctttt atagtgattt gaaataagat gtgaacaact ctatcaggaa
    18121 agtcaaatta atttatagaa atattttagc agccaaggtg tactgttata aattcaatac
    18181 actatacttg gtggtttagc tctcctgttt tctcttttag ctttaaccag ccataaatgg
    18241 tattacgtga gatttggaaa acgtgtgatg cttctgttat actacctgtt cgctcacaat
    18301 aagagagaac ttttttacga aaatctattg aatatgccat aaaagattat accacattgt
    18361 gtactatttt tggttcattt tactatatca ctttggacta tatcggtcta gttatgtctc
    18421 aacgattata gctggatact aagagaaatc aaaaaagcac taagggagaa cgtcccaaag
    18481 tgcttaatat caaggcctca aagcctgtct tattcaataa aatattacaa catcttgttg
    18541 tagaattcaa cgacaagtgc ttcgttgatt tctgggttga tttcgtcgcg ttctggcaag
    18601 cgagtcaatg aaccttccaa cttttcagcg tcgaatgata cgaatgctgg acgtccaaga
    18661 gtagcttcta ctgcttcaag gattgctgga actttcaatg atttttcacg aactgagatc
    18721 acttgacctg gagttacgcg gtatgatggg atatcaacgc gtttcccgtc aacaaggatg
    18781 tgaccgtggt ttacgaattg acgagcttga cgacgagtag tcgcgagacc aagacggtaa
    18841 acaacgttat ccaaacgacg ctccaaaaga agcataaagt tgaaacctag gattccgcct
    18901 ttgatttttg tagcttgtac gaacaagtta cggaattgtt tttcacctac accgtaagtg
    18961 aaacgaagtt tttgtttttc agccaattgc aaaccgtatt ctgacaattt agaacggttg
    19021 tttgggccgt gttgtcctgg tacgtagtta cgacgtgcca attctttacc tgtacctgta
    19081 agtgaaaggc caaggcgacg agcttgtttc caagatggtc ctgtataacg tgacatatga
    19141 atgtcctcct gatataaata atatttcggt ggaaatagtc acttagaaag ccctgattcg
    19201 tgcagatgcc cttcgcctaa acagccaagg ttacttgtca taagacacct gttgacgagc
    19261 ttcatgcttt cctgctgata tttcacacaa aatccatttt accatgaata gctggatttg
    19321 taaaggggtt ttaggcttta ttttcactac cagagaggtt gagaacgaga gtaaaggtac
    19381 ttcctagacc gtactggctg ctgactgtga tttccccacc caattgatgg gccaattcac
    19441 gcgcaatcgc aagtcctaat ccatgaccac ctgtcttcat gttacgcgaa gtttcgacac
    19501 gataaaggcg tttgaaaata ttttccaaat cctctggggc aataccctgc ccttcatcgg
    19561 tcacactgat tgaaagctgg tccttctcca gcttagccac cacttccagc ttggttcctg
    19621 gagcagaata tttaaaagcg ttatcgacca gattcaccaa gatacgagaa agcttagcat
    19681 aatctccctc aatccgggca gactctggga ttacctgcaa gtggacatct cttctctcct
    19741 gctcaatcaa aaactgaaat tcactcatgc actcaattaa gagcttgtcc agaaaaatac
    19801 tgtctttact ggtagtttcc acctgatttc tagctgtgtt tagggtcaaa aaattcaact
    19861 cctcaaccag tttattgagc ctctccgtct ggcgtccaat ggttgctaga taatgagctt
    19921 gctccgactc cttgataatc ccatccaaaa tcccttctac cgtcgcttgg atcgaagtga
    19981 taggagtctt aatatcatgc gacaactgag caatcatcaa gcccttttct cgttcgcttt
    20041 cttccaagga atcaaagctt acctgcaaat catgggacat ctcattaaaa gtttgcccta
    20101 attgctgaaa ttctacagga ccttgaacct ccaaatttga aggaaaatcc ttggccgcta
    20161 cccgcttggc atgctccttg agtttgccca acgacgtaaa gactggcaat aggagaaaga
    20221 gactaatccc agcaccgaca aggctggcaa cgatggtcat cccaagcaaa aagtaaatct
    20281 cgcctttcgc aatcagcatt ttttgaacag cccaaaaaac aaccaaaatg gttaagaggg
    20341 ttgaaataat atatccaacc aaaatataac tttttagttt catgtttgtc ctctcggttt
    20401 ctctatctta tatcccaacc cccaaactgt cttaatagtg ggcgtttggt cactactata
    20461 ttttgccagc tcctgtcgaa gagcatggat atgcacattc aaggtattgg tgtcatccac
    20521 gtagtcttct ttccagatct tttcatagag gtctgtcttg gagaaaactc gctctggatt
    20581 gctagctaaa atccacagca attcaaatga tttaacagtt aaatccagca tttcttctcc
    20641 tatttgaact tcatgactac tatgattcat ttttagattg ccaagggaaa tcagctctgt
    20701 ttcgccccca cgatgaaggc ggcgcaaaat attgtggaca cgcaaaacta gctcacgtgg
    20761 gctaaaaggc ttagcaataa aatcatctgc tcccaagctc aggccgtaaa tcttgtcctg
    20821 ttcactggtc ttagcagtaa taaataggaa aggctgctct ggtgataagt attgaacctc
    20881 actgattaaa tcataaccat ccatccgagg catcatgaca tctgtgataa tcaaatcaat
    20941 cggttttttc ttgaacagct ctagcgcttc cagtccatca tgggctacca agacctgata
    21001 acctgcctga attaagtatc tctgatgaat atctgtgatt tctacctcgt cgtcaacgag
    21061 taaaattgtc tttcccatct gtctctcctt tgataaaaac agtgctatac tgctttaagt
    21121 ataacactat ttttattgtt ttacgatgat tttaatctgc tattgaaaga aagtcctgat
    21181 tgctgattga gttgttaaac taatcttagt cagcccacta tccatcattt atttccttag
    21241 ctgattagtt ttcttctttt ttgtttttca aacctagacc accgagtaaa cctgcaagcg
    21301 caagcccaag gaaaccaata cttgccattg atgtttgagt ctcaccagta tttggtagca
    21361 tagctttatc ctctgacatc atcgtatcag acatcttgtt agcagaagca gccatgtttt
    21421 cacctgccat cgtgttggta gaacttgtca tggtgtcagc aggcatgcta tctgtagtac
    21481 ctgtagcatg attgtgattc atcggagtca cgccagaacc agagttagaa ggtgataatg
    21541 aaccatttgc tgtgtctgat gtttctttaa catttatctt aatagtgact tttttagttg
    21601 ctacgatgtt gtccaagtct ggtttacc
//
LOCUS       DAVEHY010000038        21603 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVEHY010000038 DAVEHY010000000
VERSION     DAVEHY010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.038"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(676..2403)
                     /gene="ezrA"
                     /locus_tag="VUZ44_001718"
     CDS             complement(676..2403)
                     /gene="ezrA"
                     /locus_tag="VUZ44_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU0320589.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2485..4431)
                     /gene="gyrB"
                     /locus_tag="VUZ44_001719"
     CDS             complement(2485..4431)
                     /gene="gyrB"
                     /locus_tag="VUZ44_001719"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU0320590.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4446..5009)
                     /locus_tag="VUZ44_001720"
     CDS             complement(4446..5009)
                     /locus_tag="VUZ44_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU0320591.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5094..5648)
                     /locus_tag="VUZ44_001721"
     CDS             complement(5094..5648)
                     /locus_tag="VUZ44_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU0320592.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5659..6882)
                     /locus_tag="VUZ44_001722"
     CDS             complement(5659..6882)
                     /locus_tag="VUZ44_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU0320593.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6919..9369)
                     /locus_tag="VUZ44_001723"
     CDS             complement(6919..9369)
                     /locus_tag="VUZ44_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU0320594.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9569..10498)
                     /locus_tag="VUZ44_001724"
     CDS             complement(9569..10498)
                     /locus_tag="VUZ44_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU0320595.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVHKLHPKNRFLDTGFYDYDPDMVR"
     gene            10638..10925
                     /locus_tag="VUZ44_001725"
     CDS             10638..10925
                     /locus_tag="VUZ44_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU0320596.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10959..12293)
                     /gene="ciaH"
                     /locus_tag="VUZ44_001726"
     CDS             complement(10959..12293)
                     /gene="ciaH"
                     /locus_tag="VUZ44_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU0320597.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12283..12957)
                     /gene="ciaR"
                     /locus_tag="VUZ44_001727"
     CDS             complement(12283..12957)
                     /gene="ciaR"
                     /locus_tag="VUZ44_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU0320598.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13066..15612)
                     /locus_tag="VUZ44_001728"
     CDS             complement(13066..15612)
                     /locus_tag="VUZ44_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU0320599.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15735..16175)
                     /locus_tag="VUZ44_001729"
     CDS             complement(15735..16175)
                     /locus_tag="VUZ44_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU0320600.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCVVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16150..17019)
                     /locus_tag="VUZ44_001730"
     CDS             complement(16150..17019)
                     /locus_tag="VUZ44_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU0320601.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAESHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGVKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17061..17789)
                     /locus_tag="VUZ44_001731"
     CDS             complement(17061..17789)
                     /locus_tag="VUZ44_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320602.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFEFYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17797..18276)
                     /locus_tag="VUZ44_001732"
     CDS             complement(17797..18276)
                     /locus_tag="VUZ44_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU0320603.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18287..18985)
                     /locus_tag="VUZ44_001733"
     CDS             complement(18287..18985)
                     /locus_tag="VUZ44_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU0320604.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18978..19214)
                     /locus_tag="VUZ44_001734"
     CDS             complement(18978..19214)
                     /locus_tag="VUZ44_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU0320605.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19314..20240)
                     /locus_tag="VUZ44_001735"
     CDS             complement(19314..20240)
                     /locus_tag="VUZ44_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU0320606.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20315..21130)
                     /locus_tag="VUZ44_001736"
     CDS             complement(20315..21130)
                     /locus_tag="VUZ44_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320607.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIDTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21134..21454)
                     /locus_tag="VUZ44_001737"
     CDS             complement(21134..21454)
                     /locus_tag="VUZ44_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU0320608.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6522 a         4706 c         3794 g         6581 t
ORIGIN      
        1 atttgactgt cctaatcgat ttgtactgtt cttatttcat tttactatag aacgatttga
       61 aggtgtttat gatatttagc tgtacgagag tcttttaaaa gtgttttgat ggtttggatt
      121 tcttctttag ttgatttcat attactatta tatggtgctt ttttatttta gtctggtata
      181 aatagcgaga aatatctatc ctatcttcta gaatgtcttc caaacgagaa aactctcgta
      241 aacaaagagg ttttagaggc ctatttaccg tagactaaag ttgtacaaga aaagtgcaaa
      301 taagaaatct ccagattagg aactatccgt gagttctcta gtctggagat ttttcaatag
      361 acttcattat tggacggtta ccaagttact caaagtacag atttgaagct gcagataaga
      421 ctgacgaaat cactttaata ctaaatgaaa atcaaaaagc aaactaagaa gctagcctca
      481 ggctgtactt gagtacggta aggcgacgct gacgtgattt gaagagattt tcgaagagta
      541 taaaacactg ttttgaggtg gtggataaat cggctgggca aaaactcaat ctcaggagaa
      601 aatgaagtaa atctccccac aactatagaa aaagatttga ttctgctcct cacacaataa
      661 aatctttttc ttttattaaa aacgaatcgt ttcacgtgtt ttctcatatg aggtaacaaa
      721 gcgattggtt acaccaggct ctgccacttc caatgcttga gaaatcttgt caaatgaagc
      781 gtgataatca aattcttttt caaaaatatc taaagcttcg ttaaatgctt cttgaatgcg
      841 ttcatcaaat gagcgatagc ggttagaata ttgcaagagt tgctctgtca aagttgcata
      901 ttgtacaata ttataagttt ccgtttctaa agcttccata tcattcgttg caatttcaag
      961 aactcgggta acagattcaa tgttaatcat tttttgttct aactcaacca ttaaatcctc
     1021 ggtattattg cttgccgtaa agaataactt caagaaagtt tgtggaatac ctggcagatt
     1081 gcgtttttcc atgtatcgct tgatagtatg gagacgattg acataaacat tggccttttg
     1141 acgtgcatta atatcatctt tctcaatttg tgtcaggcgc tcactaactg aaatttgctc
     1201 atcttcaata tcttttagtt gagtttgtaa atcctcaaga ttttcttcaa gaactgaata
     1261 agcttgggtt ggttcttctt gatttgaagt tacctcaaca atagctgcct caaaactctc
     1321 taattctgtc tgaatacgac gaacatggct tgcagctgtc tcaggaagta aataggtctt
     1381 gttcaaacgt gcaatatctt ctcccaataa agtattattc tctttcatat gttgaaggta
     1441 agttggaaga gttgcaagta gattttccac tactttctga gcagcaattt ctcgagtaaa
     1501 aatatcatac aaggcattga tttcctcttg tgcctgtcca ttctcatatt cggcattatc
     1561 caattccaac tgacgaatat tctcttggtt tttcttgaat gcttcataaa gcaagtggaa
     1621 acgcgcttca atatccgttt caacaaaatg ataattagca tcaattagtt tacgataacc
     1681 ggcttccaaa tcctgtaatt gatctggcaa ttctgtagaa agcgtcgtaa ccaaggctgg
     1741 aacacgatcc acaatatgac ttaaggccaa aatgtgattt tctgtattat ccaaaatcac
     1801 tgcggcttcc acagggtcac ccgatgaatt caaggttaca aattgtgaaa attcagattg
     1861 gatattttct aattgttttt caatttcatc caaggcttga ccatactgtt ctgaattttc
     1921 agcaactcta tgctgaagtt cctcaaataa atccaaagca tgaagaacac gaccactatt
     1981 tttagattct tgcttctcta agtctgccaa agcattgcga attgccgcaa tatcttcttc
     2041 aatcaaagta atttgactct caatttggtc aatttgatga ctggccttga gaaaacgaaa
     2101 tgaatggtta tagccttctg cttcaaagag attattttca atatcggcaa aagagttgag
     2161 agataaatcg acccattttt gattccattc acggaaagcc acttgacttt gtccaatcaa
     2221 gtgcatattt tttacagctt ctacttcatc atttactgga agattgtata gttcttcttt
     2281 tctttcttct agcgcctcta atctcccctc gtttcgctta cgtagaaaga ttgccactac
     2341 ataagccaga actaaaatga ctgcaattgc aaccattaaa taaattagtt gtccattaga
     2401 catatcaaac tcctttttta cttgaaacaa tcgtaacgat tatatcatat tttttagacc
     2461 aagggaacta cttctcccta ttttttagac atcaagtgta ctatagacag cattttcttc
     2521 gataaactca cgacgaggct ctactcgatc ccccatcaac atatcaaaga ttttatctgc
     2581 ttctgcagca tcatctacag aaactctagc catcaagcga tgttcgggat ccatggttgt
     2641 ttcccacagc tgatgatcgt ccatttcacc tagcccctta taacgctgaa tagtcggttt
     2701 ggtacgacct tcactataac gggctaaagc ttcttggagt ttgatttctt gatctgcacc
     2761 cggctggata tattctttaa tctcgcttcc aaccttgaca ccatagattg gtggttgggc
     2821 aatataaaca tagccagctt ctaggattgg tttcatataa cgataaatca aggttaaaag
     2881 aagggtacga atgtgggctc catcgacatc ggcatcggtc atcaaaacga gtttttggta
     2941 acgggctttc gaaacatcaa attctgcgcc aaatcctgtt cccatggctg tgaaaagact
     3001 acgaatttct tcgttagcta gaatcttatc catacttgct ttttcaacgt tcaaaatctt
     3061 accgcgaatt ggaaggatag cctgaaactc acggttacga ccagatttgg ctgatccacc
     3121 agctgagtct ccttcgacga tgaagagttc tgtttcagca gggttattag aagaacagtc
     3181 tgctagtttc cctggaaggt tggaaatttc caaaccagat tttttacgtg tgacttcacg
     3241 cgcacgcttg gcagccacac gagccttggc agccaaaatt cctttttcta cgatacgttt
     3301 ggcaatctgt ggattttcca tgaggaaatc ggagaaggct tcactgaaga ggcgattggt
     3361 aatcttgacc acttcgctat ttcccaattt ggtcttggtt tgtccttcaa actgtggatt
     3421 tgggtgttta actgagataa ctgcagttaa gccttcgcga acatcttccc ctgttagatt
     3481 gtcttcattg tctttcagta acttattttt acgagcataa tcgttgataa cacgtgtcaa
     3541 ggctgtacgg aaaccttgtt catgcgttcc accttcatgt gtatgaatat tattggcgaa
     3601 actcatgaca ttttcatggt aacccgttgt gtactgcatg gctacctcaa ctgtgatatc
     3661 atccatctca ccgtctgtat agattggtgt atcaaagatt acatccttgt tctcgttgat
     3721 atattcaacg taactagcaa tcccaccttc ataatgataa tgcttggttt gttccaaacc
     3781 ttggcgctta tcagtgatag aaatttgaag accgcgattt agaaaggcca actcttgaat
     3841 ccgtttattt aatttatcaa aatcaaagat tgttgtttca gtgaagattt ttgggtccgg
     3901 tgtgaagtga acagttgttc ctgttttatc cgtatctcca actatttcaa gatctgcgac
     3961 aacatgacca cgacggtatt cttggtaatg aatcttaccg tttttatgga catgaacgtc
     4021 taattgagtg gaaagggcat taacaactga cgaccccacc ccgtgaagac cacctgaaac
     4081 cttgtatcca ccaccgccga actttcctcc agcgtgaagg actgtaaaga cggtctcaac
     4141 agcaggacga cctgtttttt cctgaatatc gactgggata ccacgcccat catccacaac
     4201 agtaatcgaa tcatctggct caataaaaac ttgaatatgg ctggcaaatc ctgccaaggc
     4261 ctcgtcaatt gagttatcaa caatttccca gactagatgg tgaagacctt cttttgaggt
     4321 tgatccaatg tacatccctg gacgcatacg aacagcctct aagccctcta aaacttgaat
     4381 ttgactggca tcataatcct gtgcctgcag atttttgatt tcttctgtca tcttattcct
     4441 ttttcttata tgtctaatac ttgtcttaaa ttcacgatac tggtaaacaa gtgggtatca
     4501 agtcctgcag cttgacctgc ttcgatatca atcggccgat caccaatgac aagaccagag
     4561 ctaatctgat acttttctct taaataaagc atggattcgg gatttggctt tctcttaaag
     4621 cctgagctag aagtcaccac ttctgtaaaa taagctgcta tagaggtttt ttctaaaatt
     4681 tccaaaacct gatcatttcg atgagagacc aaaaaatgac ggccaccttg atttaaaatg
     4741 tcttccaata ggtcagaaac tccttcaaat aaaatcgggt gttcaagctc tctggcttca
     4801 ttttccttgt acttttctaa aaaattctct aaattgggag cgaatgtctc aatcgcaaaa
     4861 ggagtagaaa cctttaaagc ttgatagaca ctgtcatggt cttgtgtgat accatacagt
     4921 gccaatgttt caacaaatgc agctgttgaa gtttcataat tatccagtaa agttccacct
     4981 aaatcccaga tgtaatcgtg atatttcata cccttcatta tagcattttt ttatgaaaaa
     5041 agcgatgatt tccctgagtt ttccacataa aaaacgagag aataactccc gttttactga
     5101 tttttaccaa agacatctcg atagagcatt cctgttcgta aactctctgc gtcccctcct
     5161 agttgctcca ccaactcgta ggcaaaggca agggctgttg aaggaccccg actggttgtc
     5221 aactgaccat ctaccactac tgtttccttg acgtagtgac catcaaggat ttgctcttga
     5281 acgccgtcat aacaagtgta tcgcttattt ttcaatatct ctgcttgatt gagggcaatt
     5341 ggtgccgcac aaatggctgc tagtttcttc ccttcttgct cgaagctttg caattcttga
     5401 atcaaggtct gattatcacg taaatgtgca gaaccaggca tacctccagg aagaacaatc
     5461 atatcatagt ctgataaatc tccatcaaag acatgatctg ctcttacttg gattgcatgc
     5521 gaacccgtta cttgctcttc aaaaccaacc atatcacatg tgatattggc tcgacgcaag
     5581 acatctacaa ctgtcaaggc ttcaatttct tcaaagccct gagctaacat aactgctact
     5641 tttaccatga ttttctcctt atttaatttg ttttaataca acctttttcc gtttgaatgg
     5701 gacttttccg ctcttttctt cagctagatt agtctggtaa ctcatcgata aaagcaaacc
     5761 aacaccaatc agattactga taatagctga tcccccttgc gaaatgaaag gcaagggaat
     5821 ccccgtcaaa ggaagtagtc cagtcacagc accgatattc tcaaagatgt ggaagagcaa
     5881 catcataatc aaacctgtgg aaatataagt gtagaactgg ttatttgatt taagagtaat
     5941 cttcaacata cggtaaatca acatgagata gagggcaata accaggacag agccaataaa
     6001 gccaaaatct tctgcaataa ccgtaaaaat catatctgac tctcgaactg ggataagcag
     6061 attcgaagca ttaaatccct gaccaaataa gccaccactc ccaatggcaa tctgcccttg
     6121 agcctgctgg taagtcgttg tttgggcaaa ctcaaaggga ttgagccaag ccaaaatccg
     6181 attgatttgg taggtcggca ttccaatctg gtgaagaaaa gctcgtccgt ccttgctaat
     6241 aaagatagct aagaaaccag caactcctgt tacagcagtc acaaatactg ggataataat
     6301 tttccaagaa acccctgata ataaaacgat tcctgagaaa atggctacaa aaaccaaagc
     6361 cgtccccaag tcactttgaa gtgctaaaag aactaggact ggaatggtaa agagaatcat
     6421 ccagaaaatt aacaaaaagt ccagcgaaac cgtgcgtctc cattccttat gtttctttgt
     6481 aaattggaca atgacacgag ccaacatgag gatataggat atcttcataa attctgacgg
     6541 ttgaaatagg gtaattccat ttattgatac ccagtttttg gcacccgttg atgcaactaa
     6601 gcttggatta taaaatacaa tcggcaagat cataagtccc aagcctaaaa tatatagaaa
     6661 gggggtcacc ttccaaagaa attctgtatt aaagagcatg accacaaaac caatcacaag
     6721 ccccaaggca atccaggcga cctgctgccc taaaatgggc agaatattat tgggataatc
     6781 atgactaacg gctatataga tagccaccac accgatgacc agtagaaaaa atactggcaa
     6841 gagcaaactg taatcgactc ttgagtcgag agaacgtttc atatatacta accttatact
     6901 ttcatacaat actatttatc aaagttcatt aaaaaatcta tcaatagcct cgtcaacttc
     6961 ggatcgagag atggttttaa cagtcgcttc ttctgctaga gatgctacta tttgtttgcc
     7021 gtatcgtttt ccgacgattc tcctatccaa aataagagtt aaggaacgtt ggtattcacg
     7081 tctcatactt cttcccaaag cctgttttaa acgaataatg gccattggca attgataatc
     7141 ataaaaggca tttttccctt cttgattcag ttcttgatta atctttttcg tcaagggttc
     7201 ttgaggattt tggaaaggaa gcctcggtac aacttgaatc acagaaggat ggcttgaaaa
     7261 atcaactccc tcccagaaac ttgctgcacc aagcaagatt tgttgttcac ctttttcaaa
     7321 gcgtttcttt agctgatgaa catccccatt tttatactgg gccaagtggc taactgtaag
     7381 taaatccgat actgctagaa gcatgtcttt agcggtaaag agaaccaaaa tcggttgctg
     7441 gaaagcttga atttccacta gtaaagcagc tacctctctg gcatagactt ctaaggaggt
     7501 ttctgttacc agagggaaat ctttgaccat gaccacttct tgttcctgtt ttccccgaga
     7561 ttcaatcttg acaaatttag cttcaggata gcctaaaagg tctgccaaag aaaccctctg
     7621 actaatctca agagtagccg atactcccaa gacttggcaa ctctcaggaa gtaaagagga
     7681 cagaagagta cggcctgatt ttgtagaaga aatctgaatt ttcttttgac tcgtttcagt
     7741 tacttcaagc cagtaatcac cttcagctgt aaaatagcga accagctcat caaagtcttc
     7801 tacttccaat tctgaaaaat actgatggag attgtccaga gaatctaaga tatttttcct
     7861 agatttgcca gactgaaatt gttctatcaa gtagagacac tcaaagcgaa tactttctag
     7921 tatccgttgt tgaaccctgt tttcttctcc tactaaagcc ttatcaatta aatcgataat
     7981 agattgtata tcgtaggtct cttgaagcag attttctaga gctaacaaaa tcttttggac
     8041 ttcatcaata atcagtaaac ggtcactgac aaattcagga ttatcttcaa gtctggttac
     8101 gagataggca tgattagtca ctaaaagctt gcaagtctct gccctttctt gactacgttt
     8161 ccaaaaatct tccgtcacaa ataagctctg ggatgataaa ttcccatcat gacgaaggtc
     8221 tgctagaaaa tgttggtaac ggtagagttg cccgatttca tccaaatctc ctgtctctgt
     8281 ctcagtaagc cagaccaaga cttgcatttt aaagcgtcta aataagcgat tttcatcatt
     8341 ttcctgcaag gaatgataaa aggcatccaa cttcagataa ttttgtggtc cctttaagct
     8401 atgaatatct gtatggaaca cttccttgag gcgtttacct tcttcttcca tgatttgatt
     8461 ttgaagaatc tttgtcggaa cactaagaac aatttgtcgc tctttggatt gagataaagc
     8521 gggtaagaga tagccatagg ttttcccaat ccctgtcggc gcttgaatca gagagacagg
     8581 ttcatctttc aatagcaagc caacctcttt agcaaaactt tcttgttcct ccctcacttc
     8641 aaggttcaac agagaaatat ttttagaaaa gtcttgagat agttttcgta gctccagaga
     8701 agctgccgtt ttcttaaaat acagaccttg aacttggacc aagtctggag aactcaggat
     8761 agattggttg cgataagttt cctcaataac caggtaggac tcatatagga gagcgtcagc
     8821 catttccagc aagcgttcca agagaccttt aggaagctgg gtcatctttt cccgtaaaaa
     8881 aagaagtaat tctgctgtag cttgggcatc tgaaagggct gtgtgtgcgt gtttaagagg
     8941 aattcctaat tctcgacaca aaatcggcaa gctatatttt tccagttcag ggaaaaagac
     9001 ctgggccaat tcgaccgtat caacacgagg gtttcttagc tcatagcctt caaaaaataa
     9061 attttccgcc aagagattag catcaaactg aacattatgg gctacaaaaa tcccatcctc
     9121 caccaagtca aatatttttc tggcaacttg cgaaaaatca ggtgcttgcg ccagacgttg
     9181 gtctgtcaat cctgtcagtt ctttgatatg agcatccaag ggttcatgtg gattgacatc
     9241 cgtcgtatag tgatcgacga tttctccatc ctcaatcacg acaattccca cttggataat
     9301 tttagcctta ctacctgtgc tagttgcctc taaatccacc acaacatagc gattaccaat
     9361 cgttttcatt ataaaaaatt ataccaaaaa aagggccatt tggcacctgc aaacatagga
     9421 taattttcaa actcaagaac actacttttc ttaaaaatcc cagcgaatag agcattctag
     9481 cctgctgatt tttgtaaaat agtgaagaaa tacgaaaaat tgagagaaga aatgtttgca
     9541 tcttccttct ctcaacgaat catgtatttt atctaaccat gtcaggatcg tagtcataaa
     9601 atcctgtatc aaggaaacgg tttttagggt gaagtttatg aacttcttca tccagcaaga
     9661 aggcttgatc atggctaaag ttgccctctt gaatcaaatt acgcgcttgg ataaagagtt
     9721 ttgcaatctc aacaaagttc tgaccaggag tgtagagccc ttctagtttc cagcgagtaa
     9781 agccatgctc caccaattct gttaatttga tcatcaaatc aaggtcattg ttggcaaaga
     9841 tatgggtccc atgattatct tcaaaaatgg aatagtggct ctctggatca cttggctcag
     9901 ccaagaagag gtcacgttta tgcgtctttt catcatcgat atgtgtaaag ttatagtagt
     9961 tttgcaagag tggacgttta gaatgatgga tgacgctagc accgtaaacc aaaacttcag
    10021 caggaatttc caaaatctct ggcattttga aaagttcagc tgatggaatt tcacgcgcca
    10081 aaacagcctc agatgcgcca gccttttgtc cccagaagtt aatctgacga ctgctagtta
    10141 ccatggttga agcatcgtag atggtcttaa atgaataacc atcgcggtta actacgtaaa
    10201 agacgcctgc atccccaatc gtaatatagt ctgtcttgat ttcttccaag aagtctaaga
    10261 aaggcttgat acggtccatc atatcttggt gcatgagagc attgaccgca acgatcaatt
    10321 ccttaccagc atcatgaacc aacttagcga tttcacgtaa ttggtcataa ctaaaggtcg
    10381 ttggcagacg aagaccaaaa tctttctcac cgacatagat acggtctacg ccagcttcga
    10441 gtagttgttc aacttgttca atactttcag cagttgctgt aatgacaatc ttttccatag
    10501 gaaaaattat accacatttc tccaaaatca gccatgcttt gaaaatgaaa agggacttta
    10561 ttctttttgt aacctttctg taataattct ctgccgaaaa aatgataaaa taggtatgta
    10621 ctgttaagga gagaatcatg cccgtaagaa aattacaatc ctatgaggta gactatcaag
    10681 aagaattaaa ccagcagctt cctcattacc aagcttatac acctgaagcg caatctgatg
    10741 ccaatctcaa ggaaatccta ttttttatta atatcgctgt tttttgtatc tgtattgcta
    10801 tctttagttt tatcttttta gcattaaaat tatcaactgc tcttgccttt gccgcagcaa
    10861 tcggattcag cttacttgtt ttaaaagttc aacggtctat tatcaaacga aaacgtagaa
    10921 gataaatcca aaatatcgcc ccaattggag cgatattttt attttttctt tttagatggt
    10981 gtctgaatgg caatcttcac ttcaaagatt gttcccttgg gtttattatc tttgacagta
    11041 acagttcctt ttagagcatc tacaatttgc ttggctaggg ataatcctaa accaaaacca
    11101 cctttttgcc gggttctagc cttgtctact cgataaaaac ggtcaaaaat tttcttttta
    11161 tcttctgtcg aaataccgat tccattatca gaaacaagta aataaagatt gcgatcggtc
    11221 gccgagataa gaaaatcaat ttcaccatcc tcctcagtat acttgacggc attatcgaaa
    11281 agaatggtca tcagttgttt cagaagaagc tgatctgtga caattgttcg atggatacga
    11341 ttttcaaaac ggaagacacg attattttcc gaagcaatca tctcatagtt tgtgaaagtt
    11401 gtattaaaaa agctagttgg aacttctgca agctccggct taatcccatc atctctccga
    11461 gctaagttca gcaagcttgt cgttaaaaaa cgcatatttc ggacttcttc caaactcgat
    11521 gcaatgcttt cgctcacatc cataatggta gcttctggct tacgaaaaag ggtctctaag
    11581 cgattttgca aaactgcgag tggagttcgt aactcatgac tggcattttc cacaaaagac
    11641 tgttgcttct gcatactctc aagcaggggc ctaacactga ccctagctag atagagactg
    11701 gcaagtaaag acaaaatcca gaaactagcc atcacgacca caatcaattg ctcatgcttt
    11761 tgactagcct gctccaactg actggtatta atcaagacag cagcatactt gatattggtt
    11821 gaaaccgaac taatattggt ctccatcaaa atcacacgat agatttcttc ctgcccatag
    11881 ctattaaaaa cctgaatctg gtagatatgt cctagttctt tcttttctaa cttaatctta
    11941 tccaagccca aaaatcgatt tccagaaaga agttgagtaa agtctttatc aaagagaatg
    12001 acttccgtat tggaactgac attaggtttt atttctactt tactagcgtc cgccctagca
    12061 ttttctaaat ctttaatctc ttctgttgcc ctatttatag ccagctgaat aactgcttga
    12121 ggattttcac tcagtccatg aagcttatcg tccaccgaag tataaagact cgaatgcatg
    12181 acttgtaaaa taatcagagt cattgtagaa aaaatcaggg tgaagacacc gaagttgcgg
    12241 ataaaataac taaagtcatc cgcataccat gtttttttaa gtttactgaa catcttttaa
    12301 aagataccca acactacgca aagtttgcaa attctctgca aaagtggttc cctttaattt
    12361 cttacggact tttgaaacat agacttcgac aaccgaaatc gttgtatcac tatcaaatcc
    12421 ccatagacgg tcaaaaatct gcgtcttagg caaaatcaca ttttgatttt gaaggaaata
    12481 aactagtaag tcgaactctt tccccagcaa ttcgacagga gtatcttcaa ctttaacggt
    12541 attggttgat aaattaacca cgatattccc ataagtcaag gtgttttcat taaacttccc
    12601 tgaacgtttg agaagggcct gaatccgcat tttaagttct tctaggtaga aaggtttggt
    12661 cagataatca tccgctccca gttcaaatcc atgtcccttg tcatccaaac tttccttggc
    12721 agtcataatc agaactggtg tcgtaattcc cttttcacgc aattctttta agacttggaa
    12781 accatttttt tctggcaaca tcaaatccag caaaatcaag tcatagacac cactctcagc
    12841 ttcgtagaga ccttcttctc catcaaatac ctgcataaca tccgcaaaat cgtctaaaaa
    12901 gtcaaatact gaatttgaca gacctaggtc atcctcaacc aataagattt ttatcatgag
    12961 aaactcctcc ttattaaaac tattatacca aatttgcctt aaaaaaaact caactctctg
    13021 cattttacat gagatagctg agttttcttt ttattttagg cttatttatg catttccgta
    13081 ttgaagaaca actgcttcga ctgcagcttt ttcacggcta atcaagtcaa cacgtgctgc
    13141 aatttccttg attcccatac cgatgttacg gctaagagca aggtcagaaa gttgcggctc
    13201 aaagaactcc ttgtattccg ccaagcgttg ctgagtctta aatacatgag caggaaggat
    13261 aacaaagcta tcaaagctca tatctcctcc aagggctgcc ttaatccaag cccagttttc
    13321 acgcgcccaa gaccaagctg ttttctgagt tgcttgatga gctaggaatt ggtaatacca
    13381 agcagacaag tcctgtggtt tgaccacaaa tttgtccttc caagaagtaa tcaggttttg
    13441 gatattatcc gcatctgtac tgtatgcaag agctgctgcc aactggcgtt taaagacagc
    13501 atctgttgcg tgagtataag tatcaagata aagtgctaac aagtctttag tctcatgatg
    13561 tttcatctca ttaatcagaa cttgtgagcg aatagctgct gggagtcctg caagattctc
    13621 cttgtgtgtt gcgaagattt ggctagcgac ttgactagct tctgcatcat ttgagcgaat
    13681 catcatcgaa acagccagct gacgaaccaa ttcatcctca tctgattctc cgtctttagc
    13741 ttcaaaacca agacggtcat agttatgacg agccaattta gcaaccagtc ctttgaaggc
    13801 tgtttcagca tccgttcctt catcaataaa gcgctcaagg gctgaaatca cttgagaaac
    13861 agctgaaacc accagataag actcttcctt agcaagttta tcaagaactg gaagcaagtc
    13921 tgcataagaa atgtgccctg cctcagccaa caaacgacgt tcttgaacaa tttgcagttt
    13981 gcttgtgtta tcaagtgtct ctagctcagc aagaacagct tctaacaagt ctccttgata
    14041 gtcggtaata tagtgggcag tattttcagt gttgagacga agagctcctt cattttcagc
    14101 aagaagagct gcgtagccag ggatttcgat actttcagtt tcgagtgtat caggcaagcc
    14161 tttccagttg ctattgaggg gcaccaccca gagacggttc ttgtcttcgt tctcaccgat
    14221 gaagaattgt ttttgtgaaa tcttcaagac atcattttca actttgacag taagaactgg
    14281 gtaaccaggc tgttccaacc aagaatccat gaaggctgcg acatcacgtc ctgacgcttg
    14341 accaagggca tcccaaaggt cactaccaat ggtgttgctg tattggtgtt tttcaaagta
    14401 ggcgtgcaaa cctttagcaa aatcagcatc tcctagccaa cggcgaagca tgtgcatgag
    14461 acggcttcct ttggcataga cgatagcgcc gtcaaagagt gtattgattt catctggatg
    14521 tttaacttcg acgtggacag actgaacgcc atcagtagcg tcacgttcaa gagcaagagg
    14581 tactccacct gtttggaaat cttcaaagat attccagctt ggttcgatgg tatccacaca
    14641 gacgtattcc atcatattag cgaaactttc attgagccaa aggtcatccc accatttcat
    14701 agtcacgagg ttcccaaacc attggtgagc caattcatgg gccacaacaa gggcaacttg
    14761 ttgacggcta gcaaatgtag agttctcatc gacaaccaag taaacttcac ggtaggtcac
    14821 aagaccccag ttttccatag caccagctga gaagtcagga agggcgatgt ggagagattg
    14881 aggaattggg tacttaactc catagtaatc ttcgtaaaac tcgatagagc gaacagcgat
    14941 atccagtgag aaatcaagat ttgaaagtgg atgtgctttg gttgagtaga cacctaccag
    15001 ggtaccattt ttagttttag cggtcacccc ttgcaaatca ccagcaacaa aggccaacaa
    15061 gtaagaagac atgcgaggtg ttgtctcaaa cttccagata cctgtttcct tacggttttc
    15121 aacatcgatt tctggcatgt ttgacaaggc caattcacct tctgcttggt caaagcgaag
    15181 agagaggtca aaagttgctt tggcttcagg ctcatccaca catgggaaag cttcgcgcgc
    15241 aaaatggctc tcgaactgag tagacaagac ctccttcttg actccatcaa ctgtataata
    15301 agaagggtaa atccctgtca tgttgtctgt aattttacca gaaaaggcaa gaaccaattc
    15361 aacttgacca gcctcagcca attcgatatg aagggcttca ttgtcatggt caactgtaaa
    15421 tggacgagct tgacctgcaa cttctacaga ggtgatttcc aagtcttttt ggtggaggga
    15481 gatgcggtca ctctgtgctt gaccagtgat ggtcactttc ccagaaaaag tcttggtctc
    15541 acgactcaaa tctaaaaata aatcataatg ttcaggaaca aattgcttaa taaaatgttc
    15601 aactgcttgc atagttttct cctattctaa gtttaagagc tgctgctctt cttcaaacaa
    15661 acttattata tcatattttg cttgagaaaa aaggattgga cagcgatttc caaaactttc
    15721 ttccttctaa tagtctacag tgggtagacc ttgcgaaatt cttctaaaac aaccttgctt
    15781 tcaggtgtaa aagtcagccc tacttcaccc aaacagtctg tgaaaaagtc ctcatgaacc
    15841 tggcgccaat aggcaagtga tttgtctccc tcaccttcct taaaggcatg ttgcgcagaa
    15901 acttgattga agagttcaac agaaaccttt gtaatttcga caacgcagac agcctgattt
    15961 tgactatcta aaatgacatc gaaggtccct acttggggaa gtggttcgtc ttctagtaca
    16021 tagaggtcat aggctgatgc tgttgctgtc ttttctcctt taaacaccaa atccgctaaa
    16081 aggtctggtt caactccaaa agcccaagca tcgatttcat ctccgatcaa aggattgatt
    16141 tgcttgtatt tattccacat ttcttgcggt atcatgggta ctcctttgta attttttact
    16201 ttcttctttt atgtgtttaa gatgatctgg atggtcaatc tctaaatcaa aaatctctgg
    16261 aatagaactg tagtggataa tgcacttgac acccaactga ttcatttttt gtatgaaaga
    16321 agtattcaga tagcctgcta cagcaaaatt aatcttgttc tttcttgctt tatcctgcat
    16381 atctcttagc atatctaaca ttattggact ttccatatca tgccattgac tgtttctcat
    16441 agtcgcaaaa acaaaggaag tcaaatcatt cattccaact acaatctttg aaatgcccgt
    16501 ttccagtata ctagataagt caaaatacgc tgacggtaat tcaatcatcg ttccgacttt
    16561 cccagtaaag ccatactgac gcaatactgt aatagcttgt tttaattggt cggcatcatt
    16621 gacaaaagga aaaataagag acagattggg attggtttga taaacttctg taacgacatg
    16681 tgattcagcc tgaaattcat ccaaacacgc cagtaaacgc ctggttcctc tatagccaaa
    16741 caagggatgc ccttcgtcaa aaaactctct agtccccgct aaacaattgg cttctgtatt
    16801 cgttaattca gaaaaacgat accaaacttc cttatctaag taaaaggagc aaatagtatc
    16861 aagataatct tttacaaatt gctgacaact tgctaatatg atgttttgat taagctctct
    16921 caataagtat tccccacgaa tcatgccgac gtggtgaaat agttgaggat aaattttttc
    16981 aagaattttt tcgccactaa gggcaagttg atttctcata gccattcacc tcgtcttaaa
    17041 agatacaata tcatatataa ttatatcaaa atttcctcta gttcaaaagc ttcataaggt
    17101 tcagataact catatcctaa aaattctgct acttttttgg aagcctcatt atgagcatcc
    17161 caaagtggaa acatatctct atttaaactc tctagaatca ttgcagcacc aagcttttta
    17221 gcaaatccat ttccttgttc gtttggtcta gttgcaactt ccacttcaac tgctttacgg
    17281 taaactaacc ctgaggaaat cccagcaatc agttcattat ttttaagaat cacaaagcca
    17341 aatccacctt ttaaaacaaa atcctgatag aactcaaaat ccccctgtaa atcctgtgac
    17401 cattcttccg tagaaaagca gttataaata tgattatcaa taggcacaat attgtaacct
    17461 tcctctaaat gagtaactag attatttaaa aattcaactt gaaaatttgc cttatcttta
    17521 aaagaatagc gagtaaaaga atttagcccc acttttcgat gcagaaaatc ttgccaatta
    17581 gtattttctg aaataataat cttataatct aaaccatatt ttctaacaaa atcttcccaa
    17641 aatctggaat ccaactcccc tgctaggtat agaaaattcc caacatcata aaagcttgtt
    17701 gtcctatcat tgtttcggta gacagttcca atttgagatt taagaccata gagaaccata
    17761 tttttcttcc atgttttaaa tagttccatt atccctctac ttcaccttcc aattcatgta
    17821 agaagtcttg tccagttctg gaaatcctaa taattcagac ttaaccttca agactaatgg
    17881 cgatgcattt tcttctgtaa tctcttgaat atccatccaa atatatccaa gtgaatcatt
    17941 cgcaccatca gacacagctt ccgaagtcgt aacttgaggt gcactctcat tcatttcaac
    18001 atcatacaag gccatgacat ggtgaaccat aaaatttgtt aactcttctc tgacgaaaac
    18061 atcgtagatt cgaggattag agtagcttct aacagtaaat cccgtctctt ccataacttc
    18121 tctagtcagc gtttccgtca gtccttcacc aagttgctga ctgcctccag gtagatcata
    18181 ccgatgttga taagggcctc tcgctttttc aatgcaaagt aacttcccat tttctaagca
    18241 aacagcgtag actccaaagt gttttttgat ttccatccaa ctcctcctac ttcaaagacc
    18301 agccaccatc tattgtcaag atttgtcctt gcatggcgct cgcttttcca cttgctaaaa
    18361 aaagactaag ctctgctatt tcctctggct caatccagcg cttgattggg gtttcactag
    18421 ccacccagtc agccaaacca cctggttcaa aatccgcagc ggtcatagct gtcttgactg
    18481 ctcctggagc gatcccaaag acctgaatcc cagcttcagc atagtctaga gccaactgct
    18541 tggtgaagcc agccaaggca tgcttggatg aagtataggc gtgaccacct ccacctgcta
    18601 ggctagaagc aatggaacac atattgatga tgattccctt tttattttcc agcatttgtg
    18661 tcaaataata ccgagtcaac tctactggaa taatgtagtt gatttcaaaa atctcttgaa
    18721 tgtcctgcgc cgtttgttcc aacagtggtt tgtaatcatc caaaactccg gcagtattac
    18781 acaaaacatc cacctgaggg caccagtcaa aaataggttc caagtccaag gtcaaatctc
    18841 tctgtaaaaa gtgaaaatca ccctctaaga gtggcttttc accttggtca actccataaa
    18901 cttgatagcc cttctctaaa aagaggcgag cttgagccaa tccgatccct gaactcactc
    18961 ctgtaatgag tacacgttta gtcatgcact tctacccaat ccgttgccaa aacatcacaa
    19021 gctgtcgggc tccacatgga aaaaccttct ccttctccag acacgttgat taggaaatag
    19081 ggtgtcactt caagtgcaag cccattttgc tcgatggtat caaagagttg gacatagttt
    19141 tcagcacctc cccaaccagt tcgtacatat tttttcttag cctttaagcc aggtagaatt
    19201 tcttcaaatg tcatgttttt ctcctttaat gtcaataatt ctccccttca ttataacaaa
    19261 aaaaccgctt taaaacggct ttttgactgt gatttattta catcttcttc tacttacggc
    19321 aaattattcc ctgcagcaag ataaatttca taccattctt ttcttgttaa gctaaagttt
    19381 gccgcttggc taacttctct caagtgctta ggatttgtgg tacctacaac tgcctgcatt
    19441 tttgctggat aacgcaatat ccaagaaatg gcaatagttg aagaggttac tccatattta
    19501 atagctaaac gatcaagtac ttgatttaaa gcttgaaatt tctcatttcc aacaaaattc
    19561 cctttaaaat acccgaattg taagacagac catgcttgaa tgaccacatc gtgtaatttg
    19621 caatattcaa aaatgctgcc atctcgcata gctgcttgac tatcttccat attaacatga
    19681 aaagctgatt caaatcctgg agtaaaagcc gcactcaatt gtagctgatt aacagctaac
    19741 ggctgcttga catctttttt aagcaactcc atcatcatag gattttgatt agaaactcca
    19801 aaatctcgaa ctttaccttg tttataaagg agatcaaagg cttctgctac ttggtcagat
    19861 tccatcaaag catctggtcg atgaaggagc aagctatcta gatgatcaat cttcaatctt
    19921 tgcaaaatac cgtctactga ttttataata tagtccttag aaaaatcaaa ataggtaaat
    19981 tcttcaatgc gaatgccaca tttggactga atccacatct tttctcttaa atctggacga
    20041 ttttttagga caagacctaa cagttcttca caacgaccac gaccataaat atcagccaag
    20101 tcgaaggcat tgattccaac agaaagtgct gtttctacaa gctcttcaac ttcttttaca
    20161 gacttatctt ttattctcat cattccgaga acaatttctg ataattcttt gtcatcttga
    20221 ccaagagtta tgtatctcat caaatttttc tcctttaatt tctaacattc ttcccttcat
    20281 tataacaaaa aaccgctttg caacggcttt ttgactatac ttcactccat tttatcttct
    20341 taaacccacg gaacaagaca aagattccaa taaagaggac agctaaagga ataacttttg
    20401 taaggaaaac atttgaaatt cccatccact cataataacg gagcagagaa cccaccacaa
    20461 gatgggcaat aatcatactg acaaatggac gaaagaccgc ttctttccaa ttccaaatac
    20521 cgataactag cgaaatcgta aagacagaca aactatccca gggagccgga atataaaagg
    20581 ctccttcttg tatgaagctt gccattccta catatcctaa aacaactaga agaactatag
    20641 tcccaacaac aatgtaagtg tcaattttca ttttaggaga atcttggact aaacttcttc
    20701 gtaaaattgt ggccacaagt ccaaatccaa tcagaaaaat aagaagttgc cctaaaaatg
    20761 tgagcaaatt gactgttaag agaggacctt tagaaaaatc acttagtagt tgataataac
    20821 gtaataccgc caggacaaga attggcgtca aaagggactc tttgatagaa ctgcgaggtg
    20881 ctcccttgag aatctctttc attatttttt taggattctt acctagataa tcctctgcac
    20941 tcatgccatc tcgttctgct tctgagaaat ctagcatcat caaatagatc tgctctctga
    21001 gatagtcttc atcatagaga aatccagcaa gattaaaact ttcccacaac tcctcaaaat
    21061 acttttgatt ctcctcagaa aactcatgta gcaaagcgct tgtttcttcg taatacttca
    21121 ttttcttcat ggtttaaccc ccattcttaa tcccttctac tttttgactc aaatcgtccc
    21181 attgttgcca aaagactgag acacgctctt ctccttcttt cattaatgaa aaatacttcc
    21241 gatctggacc atctggcgac gggcgcatgt cgcctcttat ccattgattt ttttctaact
    21301 tttgcaacaa aggataaata gttcctggaa cgatagtatc aaatccagcc tctcgcaaag
    21361 tctgaaccaa ctcataacca taccgctctt tttgaccaat catatccaag acacaacctt
    21421 caagaacacc ttttaatagc tgagtttctt tcatcacttc tcccttctaa tctattttgt
    21481 aatacctact agtaacttca cctatagtat attacttcta cactagtttg taaagcataa
    21541 tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccctac cgtatgtatg
    21601 gtt
//
LOCUS       DAVEHY010000039        21527 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVEHY010000039 DAVEHY010000000
VERSION     DAVEHY010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.039"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(217..1779)
                     /gene="guaA"
                     /locus_tag="VUZ44_001738"
     CDS             complement(217..1779)
                     /gene="guaA"
                     /locus_tag="VUZ44_001738"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU0320609.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            1921..2619
                     /locus_tag="VUZ44_001739"
     CDS             1921..2619
                     /locus_tag="VUZ44_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU0320610.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLENGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2662..3558)
                     /locus_tag="VUZ44_001740"
     CDS             complement(2662..3558)
                     /locus_tag="VUZ44_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU0320611.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGALQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3567..4502)
                     /locus_tag="VUZ44_001741"
     CDS             complement(3567..4502)
                     /locus_tag="VUZ44_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU0320612.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4499..5224)
                     /locus_tag="VUZ44_001742"
     CDS             complement(4499..5224)
                     /locus_tag="VUZ44_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU0320613.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5308..5943)
                     /locus_tag="VUZ44_001743"
     CDS             complement(5308..5943)
                     /locus_tag="VUZ44_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU0320614.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYEALSKALKDYLY"
     gene            complement(5945..6772)
                     /locus_tag="VUZ44_001744"
     CDS             complement(5945..6772)
                     /locus_tag="VUZ44_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU0320615.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6794..7129)
                     /locus_tag="VUZ44_001745"
     CDS             complement(6794..7129)
                     /locus_tag="VUZ44_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEU0320616.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7130..7846)
                     /locus_tag="VUZ44_001746"
     CDS             complement(7130..7846)
                     /locus_tag="VUZ44_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEU0320617.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEETINKDHYLAGYPLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYDFNGIEQYISQEDYNRYLSD
                     LNEDKMKVEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            8359..8970
                     /locus_tag="VUZ44_001747"
     CDS             8359..8970
                     /locus_tag="VUZ44_001747"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU0320618.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9015..9743
                     /gene="rlmB"
                     /locus_tag="VUZ44_001748"
     CDS             9015..9743
                     /gene="rlmB"
                     /locus_tag="VUZ44_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU0320619.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9782..10693)
                     /gene="trxB"
                     /locus_tag="VUZ44_001749"
     CDS             complement(9782..10693)
                     /gene="trxB"
                     /locus_tag="VUZ44_001749"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU0320620.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10759..10983)
                     /locus_tag="VUZ44_001750"
     CDS             complement(10759..10983)
                     /locus_tag="VUZ44_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU0320621.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11061..11804)
                     /locus_tag="VUZ44_001751"
     CDS             complement(11061..11804)
                     /locus_tag="VUZ44_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU0320622.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMPFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11804..12604)
                     /locus_tag="VUZ44_001752"
     CDS             complement(11804..12604)
                     /locus_tag="VUZ44_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU0320623.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12762..13118)
                     /locus_tag="VUZ44_001753"
     CDS             complement(12762..13118)
                     /locus_tag="VUZ44_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU0320624.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13112..13642)
                     /locus_tag="VUZ44_001754"
     CDS             complement(13112..13642)
                     /locus_tag="VUZ44_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU0320625.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(13642..14136)
                     /locus_tag="VUZ44_001755"
     CDS             complement(13642..14136)
                     /locus_tag="VUZ44_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320626.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSSEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14271..14717
                     /locus_tag="VUZ44_001756"
     CDS             14271..14717
                     /locus_tag="VUZ44_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU0320627.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14714..15361
                     /locus_tag="VUZ44_001757"
     CDS             14714..15361
                     /locus_tag="VUZ44_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU0320628.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15382..15963)
                     /gene="pdxT"
                     /locus_tag="VUZ44_001758"
     CDS             complement(15382..15963)
                     /gene="pdxT"
                     /locus_tag="VUZ44_001758"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU0320629.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(15964..16839)
                     /gene="pdxS"
                     /locus_tag="VUZ44_001759"
     CDS             complement(15964..16839)
                     /gene="pdxS"
                     /locus_tag="VUZ44_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU0320630.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(16991..18370)
                     /locus_tag="VUZ44_001760"
     CDS             complement(16991..18370)
                     /locus_tag="VUZ44_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU0320631.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            18665..19588
                     /locus_tag="VUZ44_001761"
     CDS             18665..19588
                     /locus_tag="VUZ44_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU0320632.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIKLDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19648..20253
                     /locus_tag="VUZ44_001762"
     CDS             19648..20253
                     /locus_tag="VUZ44_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU0320633.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20272..21516
                     /locus_tag="VUZ44_001763"
     CDS             20272..21516
                     /locus_tag="VUZ44_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU0320634.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGDHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
BASE COUNT         6403 a         4860 c         3901 g         6363 t
ORIGIN      
        1 atattagaaa gttggctctc taattaaatt aattctcatt atatatatca aaagaccgca
       61 gcttgaaaac tacggtctaa ttttttgtcc aaatgtaaac cacttggaac tattattcaa
      121 tttattcttt ttagcaaatg ttcccgtttt aatcccagtt acagttttta atcctctgta
      181 accgttgatt ttacaaagct tttaattttt ttgcgattat tcccactcaa ctgttgcagg
      241 tggtttactt gtaatatcgt agacgatacg gttaacatga tccacttcat ttacgatacg
      301 tactgagatt ttttgaagta cttcccatgg aattttggca aaatcagcag tcataccatc
      361 gatagaagtg atagcacgga ttgcaatcgt gtagtcatac gtacgaccgt cacccataac
      421 accgactgag cgaacgcctg tgttaacagt gaagtattgc caaatatcgc ggtcaagtcc
      481 agctttagcg atttcttcac gaagaatagc gtctgattca cgaacggttt caagtttctc
      541 ttcagtgatt tcacccatga cacggatagc aagtcctggt cctgggaatg gttggcgcca
      601 tacgatgtgg tctggcatac caagctctgt accaagagca cgaacttcat ccttgtaaag
      661 agtattgagt ggttcaatca gttcaaactg catatcttct ggaagaccac ccacgttgtg
      721 gtgtgacttg atagtttgag ctgtatccgt accagactcg ataacatctg tatataaagt
      781 accttgagca aggaatttca catctttgag cttgcttgct tcgtcatcga atacatagac
      841 aaactcgtta ccgatgattt tacgtttttg ttcaggatca gaaacgccag caagtttgtc
      901 aaggaaacgt ttagcagcgt ctgctttgac gatattcaaa ccaaacttac caccgagcat
      961 gtccataact tgatcagctt cgcctttacg aagaagaccg tggtctacga agatacagat
     1021 caattgatcg ccaatcgctt tttggagaag aaccccaacg acagatgagt caacaccacc
     1081 tgatagacca agaaggacac gtttatcacc gacggtttca cgaatttttt tgatctgcat
     1141 atcaatgaaa ttatccattg accagtcacc tttagcctta caaatgttaa gggcaaagtt
     1201 acgaaggata tcatttccgt atacagaatg acgaacttct gggtggaatt ggataccgta
     1261 aatgtgttta tctgggtttt cgatggctgc gtatgggcag tcagctgatg tacctgtacg
     1321 aacaaagtca gcaggaatct cagtaaccgc atcaccatgg ctcatcaaaa cagtctgttc
     1381 atcaggtgtt gattcaaaaa gcgctgatgg tgtgtgagtt agggttgatt gaccgtattc
     1441 acgatttcca gcatcacctg caggaacaac ttttcctcca agtttatggg tcaataactg
     1501 cataccataa cagattccca aaattggaat tcctagttcg aagatttctg ggtcaatgtc
     1561 aaatgaacca tcttcatata cagaatttgg accacctgat agaataattc ctacaggatt
     1621 gacttcacga acttcagcag ctgaaatttt atggcttttt agttctgaaa aaacaccaat
     1681 ctcacggata cggcgtgaaa tcagctggtt gtactggcta ccatagtcca atacgatgat
     1741 tttttctaca tcttgcaaat cagttgaaat gttgctcatc tttttccttt ctcaaaagaa
     1801 atatcttttc tcaatattct atcacaaata agggcgaatt accaactaaa caaggcgaag
     1861 tttgactttt tctagtttat tggggtacaa tagagaaaag atagaaatga agtgaaaaat
     1921 atgctacctg cttatatgaa aatccatgat cagataaaaa aggatattga cgagcaccgt
     1981 tgggctattg gtgagaggct tcccagtgaa agagatttag ctgagcagtt tgcggtcagt
     2041 cgcatgaccc tccgccaagc cgtatctcta ttagtcgaag aaggcgtctt agagcgccgt
     2101 gtaggaagcg gcacctttgt ttccagtact cgagtacaag aaaagatgcg agggacaacc
     2161 agttttactg aaattgtcaa atcccaaggt aaagttccct ctagccagct catttcctac
     2221 aaaaaaacca ttcccaatga gcaagaagtt gccaagctag gaatttttcc aacggacaat
     2281 attatccgaa tggagcgggt ccgctatgcc gaccaagttc ccctagttta tgaagttgct
     2341 tctattcctg aaaaattcat taaggacttt aaaaaagaag aaatcaccag tcatttcttc
     2401 caaaccttgc aaaaacatgg ctatcgtatc ggcaaatctc aacagaccat ctatgctcgc
     2461 cttgctaaag aaaagattgc ccactatttg gaagttgaaa aaggacatgc tattcttgga
     2521 ttgacccagg tttcctacct agaaaatggt actgcttttg aatacgtaaa aagtcaatat
     2581 gtaggcgaac gctttgaatt ttatcttgaa aataattaga ttaccacgca aaaactctct
     2641 gtcacggaca aagagtcttt tttatttttc taagaataaa tctttcaaag aaatcaaagt
     2701 tacagcaaat aatatcattg ccataccaag aaaatcaatg ggataaaatt gttcattcat
     2761 tattaagaag gcaaagaaaa ccgccgatat tggctcaatt gaagccaaca agcttgactt
     2821 gaccggtcct atcagactgg ctcctttaag gaaagctgta taggcaaaaa cagtcccgat
     2881 aaggataatg cctgcaaacg caaggagaaa atcaagacta gttgggatat cggcctgtag
     2941 agcccctgta aaaggaaggg cgaccaaacc tgctatgacc attcccacac caatgaccaa
     3001 gctgctcccc cactttttaa tcaaggctat gggtaaaatg atatacagag cataagtcaa
     3061 ggcagaaaag agaccccaga acaggccagc aggtgtcatg gataactggt ccaactgccc
     3121 atgtgttgcg atcaggaagg ttcctccgat ggcgaatatg atggaaacta tctctcccag
     3181 tgtcggtgcc accctatcct tgatacagct ataaattaaa attccgacag gacaaacata
     3241 ctgaagcacc gtcgctgttc ccgcattggt ctcctgaata gcagacagat aggcgaattg
     3301 gttgagaaaa agaccaatca gagcaaaaat aagaagagac agcaaactct ttctatcctt
     3361 taaaaagacc agtattttat cctttgcagt agcataagcc aagagcatga gaattccacc
     3421 agcgattaaa agacgcaagt tggtcaagac cagagccgaa attccgtgtg ccattaggta
     3481 ttggccactc gttcctgaca acccccaagc aataccagcc acaactgtta gtaaagtccc
     3541 ttttaaacta tttgacatgt ctctccttac tcttctttgc gaatcaagtt catcacttga
     3601 ttgcggtcta atatccattg agctctctcg tccttttcat aggtacgatt cgataggaaa
     3661 atagtggctt cttgcttctg acgattccac atgataaagg tacctgtata gcccgtatgg
     3721 tctagccaat ctccttccaa attccatgct aaagaacgtt ccttgtcatc caaaggagaa
     3781 aaattttgat ttaagtctct tgcaaaatca tctgctaaat agtgttctaa aaaggtttgt
     3841 aaatccttta tagtcgaaaa taaaccagca ctcccagcat gtctacccag gagacgagcc
     3901 ttgggatcat gcactatgcc tgcctctaca cctctaactg ttggaacagc aagctcaact
     3961 ggcccaaact tagtttccgt cattccccaa ggtttccaga cttgatcctt taaaatcaca
     4021 tccaaatctt gattaaaaat tctttccaaa ataaagccca acagcaaaaa atggacatcc
     4081 gaataaagaa aggctggctg acttcgtctg ttgagatgaa acatcgcttc ctttaattca
     4141 ggggctgtta aaagatcacg attaggaata aaaggatcaa ggtctgttgc atgagtcaag
     4201 agctggcgaa tagtgatgtc tggataatca ctctcaggta aaaaatctat taccagtcta
     4261 tcaatatcta attgacctat ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc
     4321 ttgctgacac tagctaggtc ataaactagt cctgcctcag tctgcaagcc atgctctggg
     4381 gcactctggc ctaaatagaa ctctgtccat tgattgtcct taaaatacgc aaaagaggct
     4441 ccgggataaa ttcctgcctc gatttgttct tctatttttt taataatctt ggtccacttc
     4501 atacttcttc aaaccacaat tcaacattat ttctatcttt accaaggaag aatttttcag
     4561 acttaggaat aaaatattca gtagactcaa acttctggcg aagacttgct atgtctaatt
     4621 cattgaccaa gaacttgagc atagataagt cccaggtaac cgtattgtcc acagtcaaat
     4681 cctgcccctg agctggaata aaatcaaggg atgccccaat ttcagatgat tccaagaaac
     4741 tttcgatatc agttgggaga tgtaattcca tagaaatctc aaatttactt aaagaaattg
     4801 atgccaaatc tgtttgaaat tcaggctttt ctcctacttc tactagactt gctctgtcat
     4861 cttccgcatg aatcaaaatc aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat
     4921 tttgaccttt atataatcga tgaatcgaat ctgttttaga taagattcct tcaatttcta
     4981 agggattttc caccttgaca atcaatctag ctagtttttt tcttccctct accttacgag
     5041 tacgcatact gggagcttct tctaaaacca gcttttcaag acccgtttgg tcacctagtg
     5101 acagaaaggc cgattcttct aacaaggcct tcattccaag ggtttcaata taaaatgttt
     5161 catttaattt tctattatta gcttttaaag taggaataat ccgtacaatc tgatttacat
     5221 tcataaattc ctccgtcact ttttatttta aaggatttta gaatttttta caagatatta
     5281 tgctcaaatt taacattatt tagctattta gtaaagatag tctttcaagg cttttgacaa
     5341 agcctcataa ccagcaatac tgaggtgcag tccatcagtt gtatattctt ttttgagttg
     5401 gcctgcttgg tctgtcaaac aatcaaatac tggcacaaat tccacctgca tataggcaga
     5461 tgcaagctct tgataggctt gattccaatt ctgaattttt tcattcgagc ggatatagac
     5521 tgcctgctgg tacttctctc cctcattgac aggcaaaatg gaaagcaatt taatctctgt
     5581 caatggataa tcgcgagcaa cggattgaat gatagcttcg agattattga gagcctcatt
     5641 cacaggaaca tcctttccga tatcatttgt cccaatcaga agaaaaattt tatctactgc
     5701 tccaccatat agatgagcat caaggttctc tagtaacagt cctgtctgat agccacgaat
     5761 tcctcgattg acaatcgtct ttgaagtccc aaatagctcc tgtagaggat aatactcgac
     5821 aatggaatcc ccaataaaaa gaatgtttgg ttctacaaca gaaatgtgat ttagatgacg
     5881 atatttggtt tgaatttttt cttgttcctt taggagccaa ttttctaata actgtactgc
     5941 cacttcattc tcctttttct aaccagtttt ccaagacttg ataaactcct ccttggctgt
     6001 tggctggtgc tagagcagtc gccacagctt tggctttctc atcagcattt tccatcgcat
     6061 aggcaattcc agccatttca agcatttcaa catcattttc actatcacca aaagccatga
     6121 tttcttggga tttcaagtcc cagcgcttga gtaattcctc caagccccat gctttatgaa
     6181 tcccagcttg gaggatatca atgcaaccat agccactgga tacagctcgg acacggccat
     6241 caaagagagc attgatttct tccaaaaccg aactcaaacg ttcctcacca acaaccatgc
     6301 tcatcttgag cacaccacca aagaggtcag atgttaattc atccacaaat tgcatccgtt
     6361 ggtagaattt ttcaatcatt tctggagtca taaaactttc aagatctgta aaaatcgtac
     6421 cttccttgac aaaatcaccc ttcatccccg ttacaacaaa ctggtcctga cacgctcgac
     6481 ccttgaaatg agccaaagcc ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca
     6541 attcattgtt ttcaaaaata cgagcgccat tagcaacaac cagaaccact cgatccacca
     6601 agggactcag tagttgtctc atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa
     6661 tgcccctttg atccaactga tctaaaatct tttccaatcg tgggagatca agctgacctc
     6721 tagcatccag caaggtccca tccatatctg tcgcaattac cttaatcatc atttactttc
     6781 ctctggattc aagctaatac cacttcaatc ccacatgttc attcatttct ttataggctg
     6841 tatcaattcg ttccttagtc gcttcatcta actggtcacg atgactgcca tcctctataa
     6901 aatcttccaa aatataagtt tggtaatgat acaagggata tccttctggt gaaaaggttc
     6961 cctttggtgt tcgattgacc caagtaggat gagctttagc tgttccgata gttgtttttc
     7021 catccttctt cttgatggtg acatccatga gaacaccacg ttcagtccac ttagcattct
     7081 cttcatctcc catagattca atccgttgat tggaaatgaa gttccccatt taatagataa
     7141 tgagtttctt atctccatct ttttcaaccg tttcagatgg ttcaacaacg tgaggatgcc
     7201 ctccaaagat aatatccgct ccccaatcga tcatcttgtg ataaagagct ttttgttctt
     7261 cagttggttc caatcgatac tcaacaccca tctgaagcat gataatggtg atatctgctt
     7321 ccttctctgc ccgttcaatt tcaaccttca tcttatcttc gtttaaatct gaaagataac
     7381 gattatagtc ttcctgagaa atatactgct caattccatt gaaatcatag gaataggcta
     7441 acaatgcaac cttgatacca ttcacttcct taatgaccag cggagcctga tcacgtggtt
     7501 cgtgcgtata aactccgatt ggagtgattc cagctttctc aataatatcg gccgttgaaa
     7561 taactccctc aatttgcgaa tccaaaatat gattatgagc taaatccagc acatgataac
     7621 ctgcctcctt aatagcatcc ataacttcag caggagcatt aaagagagga taacccgcta
     7681 aataatgatc cttattaatg gtttcttcaa aatcaccaat agctaaatct gcttgcttga
     7741 accaaggagt cacatactca aaattttcat gaaagtcata ggtaccgtct tcttttttag
     7801 ctgaaaagaa aagtccatcg tggtagagca aatccccgtg ggccataatt ctggcagttt
     7861 tttcctcttc ctactcctga gacttttgct tagtcccctc ttgagaaata gtatctcgtt
     7921 tttgactagt caagggattc cttggaagct ttcaaacaac aagaccaagc ccattgataa
     7981 atcaactgct agcaagagta tcgccacaaa tcccttattg ctccacttgc gataactcct
     8041 aaaaagttta ccaagccctt cataaaacga aaagctaaac caccctgatt tcgattttgt
     8101 cttctttgta tcttcattct ccctactttc ttatgcaagc cttttctttt tattatatca
     8161 cagataagta tttctttcac aattgaattg aacttcccat ctattttcta taaatcctaa
     8221 atgccataat gctttcaatt cttgtcattt tgtgatatca tgtagaggaa atgaactaat
     8281 ccacagtggc ttattccaag tataccactt gggctttggc agtagctaac tgcactaaac
     8341 ataatataag gagagaaaat gtctgcaata gaacgtatta caaaagctgc tcacttaatt
     8401 gatatgaacg atattatccg tgaagggaat cctactctac gcgcgattgc tgaggaagtc
     8461 actttccccc tatctgacca ggaaatcatc ctaggcgaaa agatgatgca attccttaaa
     8521 cattcccaag accctgtcat ggctgaaaaa atgggactcc gcggtggtgt tggactggct
     8581 gctccccagt tagatatctc aaaacgcatt atcgctgttt tggtacctaa tattgttgaa
     8641 gaaggcgaaa ctccacagga agcctacgat ttggaagcca ttatgtacaa tccaaaaatc
     8701 gtctctcact ctgttcaaga tgctgctctt ggcgaaggag aaggttgcct gtctgttgac
     8761 cgtaacgtgc ctggctatgt tgttcgccat gcccgcgtta ctgttgacta ctttgacaaa
     8821 gatggagaaa aacaccgtat caaactcaaa ggctacaact ccattgttgt tcagcatgaa
     8881 attgaccaca ttaacggtat catgttttac gatcgcatca atgaaaaaga cccatttgca
     8941 gttaaagatg gtttactgat tcttgaataa agaaaatccc gttgcaagac ggggttttgt
     9001 gttataatag aggcatgaaa acaaatgata ttgtctatgg cgtccacgcc gttaccgaag
     9061 ccctccttgc aaatacagga aacaaactct acctccaaga agatctccga ggtaagaatg
     9121 ttgagaaagt caaggaacta gctacagaaa agaaggtgtc catttcttgg acatcaaaaa
     9181 aatctctctc tgagattact gaaggtgctg ttcatcaagg ttttgttcta cgagtgtctg
     9241 aatttgccta tagcgagcta gattacatcc ttgcaaaaac acgccaagaa gaaaatccac
     9301 ttctattgat tctagatggt ctaaccgatc cccataatct gggttctatc ttgcgaacag
     9361 ccgatgcgac caatgtttca ggtgtcatca ttcccaagca ccgtgctgtc ggagtaactc
     9421 ctgtcgttgc caaaacagcc acaggtgcta ttgaacacgt tccaattgcc cgagtgacca
     9481 acctcagtca aaccttagat aaactcaagg atgaaggttt ctggaccttt ggaacggata
     9541 tgaacggtac tccttgccac aagtggaata caaaagggaa aatcgccctc atcattggaa
     9601 atgaaggaaa aggtatctct agcaacatca aaaaacaagt cgatgagatg attaccattc
     9661 cgatgaatgg acatgttcaa agccttaatg ccagtgttgc tgcggccatt ctcatgtacg
     9721 aagttttccg aaatagacta taaaaaagtt tccagtcatc tgattggaaa cttttttatg
     9781 attaactatg ttctgtaatg aatttatagg cttcttgacc agcgatagct ccatctccaa
     9841 ccgctgttgt tacttggcga aggtctttca agcgaacatc tccaactgca aagataccgt
     9901 cgactgcagt tttcatgtgg ttatctgtca caatccatcc tgcctgatct tggatattca
     9961 attctttaac aaaatcgcta agagggtcca aaccaacata gataaagaca ccaccgaagg
    10021 cttgttctgt cacttgacct gttttcacat tttcaaatac gactgattct actcggtttt
    10081 cacccttgat ttcccttact acagaatccc agataaagct gattttttca ttcgcaaagg
    10141 cgcgatcttg taaaaccttt tgggcacgaa gttggtcacg acggtgaaca atggtaacag
    10201 tcttagcaaa acgagtcaag aagagggctt cttcaacagc tgaatctcca ccaccaacta
    10261 ccaataaatc ttggtcacgg aagaaagcac catcacacac agcacagtaa gaaacaccac
    10321 gactgttcag ttcttcttct ccaggcactc ccaaaggacg gtgtttagaa ccagttgcta
    10381 cgataactgt acgtgtttca tatgtttggt catcagtcat cactttctta aaatcaccat
    10441 ggtcttcgac attttcaaca taaccataaa tgtgctcaac accaagattt tcaagtggtt
    10501 caaacatctt ttcagccaat tcaggtccac taatattagc gtatcctggg taattttcga
    10561 tatcagatgt attattcatc tgaccacctg gcagaccacc ttcaatcaaa gctactttta
    10621 gattgcttcg agcagcatac aaggccgcag tcatccctgc aggtccagca ccgataataa
    10681 tagtatcgta catatagatt ccttctttct tgttgtaact atctttattc taactctttc
    10741 ttgtcaatca cgcaaggatt atgccttgaa aacaagaatt aaactcataa ccgcaaagga
    10801 taatactggg acaaccaaga ctccaatcat aatcatatca tagagatggg cttggcgagc
    10861 cctggctgtc ttatcaactc ccgacatggc tctcagacca atccaaatcc ctaaaaaaat
    10921 cagaacaagg atggtggtca agatcaaact ctcgaaatat aaagaaaata gttgcagtag
    10981 catgatttct ctcatttcta tcttttttaa agagtaaact cagctagtcc aactaactga
    11041 gttttccttt atctattata tcaaatataa gtccgtttgt aactagcgaa gaattctttt
    11101 gtccgctctt ctttaggggt gtggataatc tcatccggag ttccagactc gatgattttc
    11161 cccttatcta agaagagaat tttatccgca acttgggcta caaagggcat gtcatgactg
    11221 accaaaatca tggtctgacc tgacttagca gcatctgcaa tagacttttc tacttcaccg
    11281 accaattctg ggtcaagggc tgaagttggt tcgtctaaga gcaaaacatc tggtttcata
    11341 gcaagcgcac gcgctagggc aacccgttgc ttctgtccac ctgataaatg gcgaggataa
    11401 tggttttcac ggtccgaaag cccaacctta gccaactctt ccttggcaat cttagtcgct
    11461 tcttggtcag ataatttctt gacaacaacc aagccttctt tcacattatc aagtgctgtt
    11521 cggcgttcaa ataaattaaa ctgttggaaa accatagaca acttacggcg tagggcaagg
    11581 atttcttctt gagtgatttt agaaaaatca actgaaaaac catcaatctg aatagagcca
    11641 ctgtcaggtg tttcaagata attgagactg cgaagaaagg ttgattttcc agctcctgaa
    11701 gaaccaatca aggctacaac ttcccctttt tgaatatcca agttcagatg atccaagaca
    11761 gtctgtcctg aaaaggattt gcttaaattc gaaatcttaa tcattaacga aggtctcctt
    11821 tcacatctgt ttgcactgta tcaggtgcag aaatagccat ttttctctcg atgaaacgac
    11881 cgaggctttc aattccgata ttgactaccc aataaacaag ggcaacggag atgaagcgtt
    11941 caaaatagcg ataatcagct ccacctagaa tctgagcttg ggcaaagact tccacaacac
    12001 ccgcactaaa agctagagat gttcccttgg tcaaaccgat gagggaatta atcaaggttg
    12061 gagtagctac caccgctgca ttaggaataa tcactcgtcg ataaacttgc gctcgggtca
    12121 tacccagact gcgtgccgcc tcaatctcac caggattaac tgagagaatg gctgcacgaa
    12181 tggtttcact agcataagct gcctcattaa aggcaaaagc gacaatcgca aaagctgcag
    12241 ctggaatcgc attgatattg agaccagttc cccattgctg attgagggct ttcaaagcca
    12301 aagggattcc gtagtaggtc aacatgagtt gcaccaaaat cggtgtccct tttaagaaac
    12361 taacaaagaa ggcctgcaag ggatataaaa tcttgacacg attgatcttc acaatggcaa
    12421 aaagaagcgc caaaaccaag ccaaaaaggg caccaccaat tgtcaacata attgttgttg
    12481 gaagttgttg gacaattcta gggattccat caaagaccga acgtaggcta aacagcttgc
    12541 catccggaat caattgcatc aagttttggt accaatctga tgctaaaatc gttgtaacat
    12601 tcataaaaac atcctcttct gataatgatt cattctacca tgcttctgcc gtcaatgaaa
    12661 ttatttgcta cggtcagata cagactttgt ctacctacta gtttatcata ctttgaaaca
    12721 gggaagttat atattttatc tatcaaagag atagataaaa actatttcag tcccagttct
    12781 tcataagatt ttcgataacc gatttgctta acggttccat tttctactaa aatgggccgt
    12841 tttaacaaca taccgtcact tgctagcaac tcagccgctt cttggtttga caaacttcct
    12901 accttatctt ttagccctaa ttcacggtat ttgataccac tggtgttgaa aaattgcttc
    12961 aattcaaatc ctgaggtttc tagccaattc aaaatgactt cttggctagg tgtttcttcc
    13021 acgatatgga cggctttata gtccacacct aattgattta attcttgttt tgctttttta
    13081 caagttgaac atttgggata ttcgataaat tctaacatgt gcttctcctt ctattgtttc
    13141 tatctttaaa atctactcct tcatgctcca agagccaagc tttcttttcc actcctgcag
    13201 cataacctgt cagacgcttg cctgctccca acacacgatg acaaggtact aggatagacc
    13261 aaggattgcg tcccactgct ccaccaattg cttgagcaga agccacttgc aggtcttgag
    13321 caatttgtcc ataggtcact gtctgaccat aaggaatgcc ctgtaaatag tcccaaactc
    13381 tcttttcaaa attcgttcca attggcgcca agagcaagtt ggataaatcc tgaggcttgc
    13441 ctttaaagta atcatctaag caagcaataa ctgggtctaa aataggatga ctaacaactt
    13501 cttctatcgt ttcatctcct agtcccctct caaaatgctt ctgctcctga acccaaattc
    13561 catacaaata atggtcatca gctacaagtg atagaatacc aattggtgag gagtagagga
    13621 tttttacata cttcttttgc attatttctt taatttttga taggccaagc gttcgccatc
    13681 tactggcacc ttaccaactt gtttaaaacc aagtttttca aaaatatgtt gcataacctt
    13741 gttttcagca tgcgtatctg agcgaaaatc aagataatca aaaccttcaa tcaagccctc
    13801 taagaaggtt tgagcaactc cttttccctg cacatctgct gccacagcaa tacggtgaaa
    13861 gactagatac tctgactctc cagcttgcca gtttccctca taaatagctt cataggcctc
    13921 ctctgaactc ttggtcacag cagcataggc tagcagttct ccctcttcca aggctacgta
    13981 ggcttgccct gagatgatat catcgataat aacatctgca tttggatagc cattttgcca
    14041 ctggtcacta ccagcatctg ctaaacattt tttggcatcc tccatcacct gcatgatggc
    14101 atctacttca tttggaaaag ctaaacgaat ttccatcttt tttcctcatt tctgactagt
    14161 ttctcccatc atagcataat ttaagtattt ctacaagcag ttaaaacttg actttgtgtt
    14221 tttgttattt tataatctag ttatcaaaac tatataaaaa ggagttgaaa atgaaaacta
    14281 ccttttccta cccaaaatgg gcagaaattc caaacattga cctctatctg gaccaggttt
    14341 tgctctatgt caatcaggtc tgcgccccta tctctcctaa taaagacaag ggcctaacag
    14401 catctatggt caacaattat gtgaaaaatg gttacctgac aaagcctgac aaaaaaaaat
    14461 accaacgcca acagattgcc cgtttgattg ctatcacaac cctcaagtct gtattttcta
    14521 ttcaagaaat agcccagaca cttaatactc tacaaactca agcaagttca gaccaactct
    14581 acgatgcttt tgtggactac atgaaccaag gaattgaccc agctaaccct attatccaaa
    14641 ccagctgcca aaccgttaaa ctctatcatc aaactctaga cttaatcgat catactcaag
    14701 aggaggtaat ccaatgaaca ctagtcttaa actcagcaaa caactcagtt ttggagagga
    14761 gattgctaat agcgtgaccc atgctgtggg tgcagtcatc atgcttatct tgctgcctat
    14821 ttcatccatc tatagttatg aagcacacgg atttttatcc tctatcggcg tttccatttt
    14881 cgtcatcagt ctctttctca tgttcctatc atccaccatt tatcactcta tggcctatgg
    14941 ttcgacccac aaatatgttt tgcgaatcat tgaccattct atgatttacg ttgccattgc
    15001 cggctcatac acgcccgttg tcttgacctt gatgaataac tggtttggct atctgattat
    15061 tgtcatccaa tggggaacga ccatctttgg tattctctat aaaatctttg ctaaaaaggt
    15121 caatgagaaa tttagccttg ctctttacct gattatgggc tggttggttc tggctatcat
    15181 tcctgccatt atcagtcaaa cgacacccgt tttctggagt ctcatggtaa ctggcggact
    15241 ctgttataca gttggagctg gattttatgc caagaaaaaa ccttatttcc acatgatttg
    15301 gcatctcttt atcctagctg cgtccgcact tcaatacatc gctattgttt attacatgta
    15361 aaaaagttga gaaattcaat ctcaactttt ttctttacac atattgataa agtactggtg
    15421 caagcgcaca tcatcagtca attctggatg aaaagaactt accaacatat ttttttcttg
    15481 ggctgcaaca atttgattgt tcactgttgc tagaatttct acaccctcac caacactact
    15541 gataatcgga ccacggataa aggtcattgg aatcttgcca actcccttac attctgcttc
    15601 cgtgtagaaa cttcctaatt ggcgcccata agcattacgc tcgaccacca tatccatagt
    15661 tcctagatga ctctctttct gagaagtgat ttccttagcc agcaaaatta agcccgcaca
    15721 ggtcccaaac actggtaagc cagatagaat ggcttctcgg atgggaagta gcatgttctg
    15781 gtcacgtaag agcttgccca tggttgtaga ctcaccacca ggcaaaatca aacccgacaa
    15841 gtcactctga tcttgctgaa aatcatctag atttctgagt tctacactct cgacacctaa
    15901 ttgatctagc acttttgcat gttctgcaaa ggccccttgc aaggccaata ttccgatttt
    15961 catctatttt cctcgttcag ccatgagaat ttggatttca ttttcattaa taccaaccat
    16021 ggcttctcct aaatcttcag agatttgagc taggatttga ggattacgga agttagtcac
    16081 agccttaaca atggcactcg ctcgtttaac aggatctcct gacttgaaaa tacctgaacc
    16141 gacaaagacc ccctctgccc ctaattgcat cattaacgca gcatctgctg gcgttgcaac
    16201 acctccagca gcgaaattta caactggcaa ttttccatgt tcatgaacat attggaccaa
    16261 ttctacaggg acttgcaaat ccttggcagc aacataaagc tcgtcctcac gtaagttttg
    16321 aatgcggcga atttcctgat tcatcatacg catatgacga acagcttgga cgatatcccc
    16381 tgtccctggt tctcctttgg tacgaatcat ggaagcacct tcagcgatac gacgcaaggc
    16441 ttcacccaaa tccttagcac cacagacaaa aggaacttgg aattctttct tatccacatg
    16501 gaaacggtca tcagctggag atagaacttc actctcgtcg atataatcaa tttcaatagc
    16561 ctctaaaatc tgagcttcaa caaaatgccc gattctgacc ttagccatta ctggaatact
    16621 aaccgcttct tggatttcct taatcatctt tgggtcgctc atgcgggaaa ctcctccagc
    16681 tgcacgaata tcagccggaa ttcgttccaa ggccatcaca gctgccgcac cagcagcttc
    16741 tgcgatacga gcctgttcag gattctgcac atccataata acaccaccct tgagcatctg
    16801 tgccaaattt ttatttagtt cataacgatt ttcagtcatt tgttttatcc tcatcatttg
    16861 tattggtagc taccttttca ttttaagtca gaacagaatg aagcacaaga taaaaaaact
    16921 ataattgtat ggggacaaat tagctaaaaa ctatctgacc ttaacttaag gccagatagc
    16981 tcattcattt ttatttttca gccgtaaggg cagccattgt gatgtagttg tatggtttgt
    17041 tgaagtgtgg caagaagaag aggtctgtca atgccaattt atcaattgtc acatgctctt
    17101 ggatagcaag tgagaacatg tggattccca tgctaattgc aatatcatgt gaaaccattt
    17161 gggcaccaag aatttcacgg ctatctttgt caaagacaat cttaattgct acttcatggt
    17221 tgtcatgttt catgaattct ggtttttgaa gatcgttaaa gcctgtttca gttgcgttgt
    17281 aaccagcagc tttcgctttt tcaagagtca aaccagttga aaccatgtga agaccgtaga
    17341 ttgagatacc atttgaacct tgaacaccga ttccttccaa ttcatgtcca caagcgttgt
    17401 aggcaccaac gataccagtg cgaacagcat ttgaagcaag agcgatatag cttgtatctt
    17461 tacgagcatt gtcataaaca gtcgcacagt caccaacagc gtaaacgcct gggatagatg
    17521 tttcttgttt cttgtctaca aggaaggcac cgttgcggaa gagttcgatc ttaccatctg
    17581 caagggctgt gtttggacgg aaaccaactg caaggataac catatccacg tcaaagcttt
    17641 ctttgtcagt aatcaagcgt tcaactttac cgtcaccttc gattgcttta acagtttgac
    17701 ctagagccaa gcggatgttg tgatcttcca agttcttcgc catcatttgt gtgaagtctt
    17761 tgtcatagta accgttcaag acagtatcaa cgatatcaac aaggacaact tcttttccaa
    17821 gacgttcaaa ggcctcagca agttcaacac cgatgtaacc accaccaaca acggcgatac
    17881 ggtcgaggtg ttggctcttg tcagaaagtt tattgataac ttcttcagca ttttggtaca
    17941 atttcacgaa ttgtacgttt tcaagagttg ctttaaattc gcggtttcct ttaacaattt
    18001 caacaccttc gattggtggc aagattggtg tagaacctgt agcgaaaatc aatttttcgt
    18061 atgattcttt gtgctctttt ccttcaactt ccgctgtaac tactttgtta tcatagtcga
    18121 ttgaaagaac aggtgagttc atgtaaactt tagcaccttt agcttccaat ttttctttat
    18181 cagaatagaa caagccttca gcaccgtcaa tttgttcacc aatccaaaga gccattccac
    18241 atcctaggaa agagatgtta gagttttggt caaatacaac aatttcgttc tcatttccaa
    18301 aattatccaa catggtattg atacatgctg taccagcgtg gttagcaccg actacaacga
    18361 ttttactcat aaaaaatttc ctgccttcat tctaaattta ccttactagt ataccattta
    18421 ccgttagcgt ttacaagggg ggtactatca tttcagcatt ttttatcaaa aataattccc
    18481 catttatcct gttttcaagc ctgatgaatt ttatgagcat atttcttgac tttttccaaa
    18541 ttttgtttgt gaaaattcta actttatggt attataataa catgaaaatg aaatgtaagg
    18601 gcttcaattt agatgattat ttgatattac aacttatttt ctataagaga aaggagttgg
    18661 tagcttgact cttcgttcac attctgaacg gctaatgggg actactatca ctatttcatt
    18721 agtggatgag caagccgata tctttctcca aaaatccttt gacttgctca aagaacttga
    18781 ataccgcttc aacgccaata gtcaagaatc tgagttgatg gaaatcaatt atcaagcagg
    18841 aatagccccc gtcacggttc atccagacct gtttgagctg atttcacttg ggttagagca
    18901 tagcctagcg ctctctagcc acctcaatat cagcattggt cccttaattc aaacctggcg
    18961 tatcggtttt tcagatgcca aggtcgccca gcctcaagaa attgaatcgg tgctgcctct
    19021 aatcaatcct catggtatca agttagattc ttctacttct actgtgtttt taaaacagaa
    19081 aggaatgaag atcgatctag gttgtttagc caaaggatac agtgcggata aggttgccca
    19141 atttcttagg aaagaggggg tgacttctgc cttgatcaat ctgggaggga atatcctgac
    19201 cattggaaaa aatcaggcaa gaggggataa cccatggcaa atcgggattc aagacccagc
    19261 caatcctagg ggaaatcatt taatgaccat ccctgttgtc aataaatctg tcgtgacttc
    19321 aggcatttat gaacgtcacc tgaccgtcga tggacaagat taccatcaca tttttgacag
    19381 tcaaacagga tatcctgttg aaacggaact agcgagtcta acaatcatct ctgataaatc
    19441 agtcgatggc gaaatctgga cgactcgact ctttggagaa agacctgctt ctatcctctg
    19501 gcaagtcgaa agtttggagg gcatcgaagt catcctcatc gataaagaag gccacctaag
    19561 ctgttcttca ggaattccta ctctatagag acaactgttt caatggaatt ttaaaattgt
    19621 attatgtaaa aagagaaagg aaatctcatg ttaaaactta ttgctattgt tggaacaaat
    19681 tcaaaacgtt ctacaaaccg tcaattgctt caatacatgc aaaaacactt tactgacaaa
    19741 gctgaaattg agcttgttga aatcaaggcc attcctgtct tcaacaaacc agctgacaag
    19801 caagtacctg ctgaaatatt ggaaattgct gctaaaatcg aagaggctga tggcgttatt
    19861 atcggtactc ctgagtatga tcactctatt ccagctgttt tgatgagcgc tcttgcttgg
    19921 ttgtcttatg gtatttaccc acttttgaac aaaccaatca tgattacagg tgcttcttac
    19981 ggtacgcttg gttcatctcg tgcccaattg caacttcgtc aaatcttgaa tgctcctgaa
    20041 atcaaggcaa atgttcttcc agatgaattc ttgctctcac actctcttca agcatttaac
    20101 ccaagtggcg acttggttga ccttgatgtt atcaagaaat tggatgccat ctttgatgac
    20161 ttccgtatct ttgtaaaaat cacagaaaaa ttacgtaatg cacaagaatt acttcgcaaa
    20221 gatgctgaag actttgactg ggaaaatttg taagatagga gaccaaaaag aatgaaattt
    20281 gttggacttg ttggatcaaa ctacgatcaa tcatataacc gtaagctctt ggaatttatc
    20341 cgtcgctact tcaaactcaa atttgaatta gaagttcttg aaattgacga agttccaatg
    20401 tttaaccaag atgaaaaatg ggatgaaagt ttccaattac gtttcttgta taacaagatt
    20461 acacgtgctg atggtgtcat tatcgccact cctgagcaca accacactat ctcagcttca
    20521 ctcaaatctg tacttgaatg gctttcatac gaagttcatc catttgaaaa caagcctgtt
    20581 atgattgtgg gtgcatcata ctatgaccaa ggaacatcac gtgctcaagt tcaccttcgt
    20641 aaaatccttg atgctccagg tgttaatgcc tacacgcttc caggtaacga attccttctt
    20701 ggtaaagcta aggaagcttt tgataacaac ggaaatatca ccaacgaagg cactgttaaa
    20761 ttccttgaaa cttgcttaga taactttgtt aaatacgtag gagtcgtttc gaaattgaaa
    20821 aaaccaaaac caatcgaatc agaagactta gattgtggaa aaccaatcgc tacaaccatc
    20881 acagaagttg accctgacga tccagaatgg gtagaaaaag ttgcagcaat cactggtgct
    20941 gtttctggtg atacctatgt caaattggac cacggtatcc taacagttaa ccaaattgat
    21001 atgttcttga aagctatgcc atttgaattg acatacgctg acgacaacaa ccaattcctc
    21061 tactacaaca acgctcacca agatccagac actatgttcg ctaaacgtgt accacctcaa
    21121 tcaggtagcc gtatgtcgac tgttcatggt tctcttccac cagcacgtat gaagaacgta
    21181 gagtgggtta tcggaacact tcgcaacgga aaccaagaat acgtccgtac gatcgttcca
    21241 ggttctcctg caggtgttat caacactcac aactaccaag caatgtacta tcctgatgga
    21301 tcatacgctg gtatcaatga aatcgtcttt aacttccaac catggcttga ctggtaccta
    21361 aaagagactg gtcaacgttt ggtgggtggt agcggaccat ttgctcctgc tgccggagat
    21421 catggagacg ccgatgctac ttctggcgct tctgattcag gggatgctgg aggccacggt
    21481 ggtgacgcag acgctacagc cggtgcaagt tactaatgat agttttt
//
LOCUS       DAVEHY010000040        21297 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVEHY010000040 DAVEHY010000000
VERSION     DAVEHY010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.040"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            501..1544
                     /locus_tag="VUZ44_001764"
     CDS             501..1544
                     /locus_tag="VUZ44_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU0320635.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1711..3798
                     /gene="topA"
                     /locus_tag="VUZ44_001765"
     CDS             1711..3798
                     /gene="topA"
                     /locus_tag="VUZ44_001765"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU0320636.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3904..4263
                     /locus_tag="VUZ44_001766"
     CDS             3904..4263
                     /locus_tag="VUZ44_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU0320637.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4356..4988
                     /locus_tag="VUZ44_001767"
     CDS             4356..4988
                     /locus_tag="VUZ44_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU0320638.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            5032..5688
                     /locus_tag="VUZ44_001768"
     CDS             5032..5688
                     /locus_tag="VUZ44_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU0320639.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5707..6339
                     /locus_tag="VUZ44_001769"
     CDS             5707..6339
                     /locus_tag="VUZ44_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU0320640.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            6367..6791
                     /locus_tag="VUZ44_001770"
                     /pseudo
     CDS             6367..6791
                     /locus_tag="VUZ44_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
     gene            6803..7840
                     /gene="leuB"
                     /locus_tag="VUZ44_001771"
     CDS             6803..7840
                     /gene="leuB"
                     /locus_tag="VUZ44_001771"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU0320641.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLVAIGSPQYDGVAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEYQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVSMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7837..8106
                     /locus_tag="VUZ44_001772"
     CDS             7837..8106
                     /locus_tag="VUZ44_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU0320642.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            8110..8469
                     /gene="leuD"
                     /locus_tag="VUZ44_001773"
     CDS             8110..8469
                     /gene="leuD"
                     /locus_tag="VUZ44_001773"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU0320643.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8688..8831
                     /locus_tag="VUZ44_001774"
     CDS             8688..8831
                     /locus_tag="VUZ44_001774"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320644.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            9092..9253
                     /locus_tag="VUZ44_001775"
     CDS             9092..9253
                     /locus_tag="VUZ44_001775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320645.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            9417..11330
                     /locus_tag="VUZ44_001776"
     CDS             9417..11330
                     /locus_tag="VUZ44_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU0320646.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADN"
     gene            11317..12555
                     /locus_tag="VUZ44_001777"
     CDS             11317..12555
                     /locus_tag="VUZ44_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU0320647.1"
                     /translation="MRITDNQHKIAKEDFVAEYPKLSQALLDRTLDNLSREDNIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIECIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRMNKIKLIRHAYFREYRKLQELCLVILSREKHGLG
                     PQAQRVHGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGLFESLRMPHSIVHFVK"
     gene            12789..13775
                     /locus_tag="VUZ44_001778"
     CDS             12789..13775
                     /locus_tag="VUZ44_001778"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU0320648.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13839..13910
                     /locus_tag="VUZ44_001779"
     tRNA            13839..13910
                     /locus_tag="VUZ44_001779"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13872..13874,aa:Arg,seq:ccg)
     gene            14093..14791
                     /locus_tag="VUZ44_001780"
     CDS             14093..14791
                     /locus_tag="VUZ44_001780"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU0320649.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14782..18321
                     /gene="smc"
                     /locus_tag="VUZ44_001781"
     CDS             14782..18321
                     /gene="smc"
                     /locus_tag="VUZ44_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU0320650.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHVLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKDNKAELDSTEEELAQVQELLTSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLDSEEVALKTLQDEMARLTESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTDLLNQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVYNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18318..19112
                     /locus_tag="VUZ44_001782"
     CDS             18318..19112
                     /locus_tag="VUZ44_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU0320651.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGNKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            19112..19930
                     /locus_tag="VUZ44_001783"
     CDS             19112..19930
                     /locus_tag="VUZ44_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU0320652.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSNQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAVANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19934..21211
                     /gene="ftsY"
                     /locus_tag="VUZ44_001784"
     CDS             19934..21211
                     /gene="ftsY"
                     /locus_tag="VUZ44_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU0320653.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYKKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
BASE COUNT         6726 a         3692 c         4764 g         6115 t
ORIGIN      
        1 atattttagc agccaaggtg tactgttata gattcaatac actataattt agtgtaattg
       61 agaaaggaga aatgattgtg attgatgttg gctaggttat gttcaatgat tcctaccgtc
      121 tcaaatcttg tcagtaagga aaaataaatt cttcaaaagt agagattaca aggcttgttt
      181 aagaaagaat tcaaagacct tgacaaataa aaataaaatg gttattataa aaaatggtct
      241 aaaatagatg atgatacttt tcgaaaatct ttttacgtca gctcagcttt gccttgctgt
      301 gttttgagca agctacggtt agcttccgag tttgattttc atttactaga aatgaaactg
      361 atgagagata tcagtagaca tttgagtcag gatattatgg aaaatgataa aaagagctcg
      421 tgagattggc atatcagact actaaagtat tgagtttgtt aggattttag cgactagtta
      481 gctgggaaag gaagatattt gtgacaaata ataaactgta ttcgttgata gaatttagaa
      541 ataaaatata tgaagaatta gaactttcca gaagtgattt agcgatttta ctatgtgcca
      601 tgcttatcgc ctctatcgga ttaaatatgg attcgactcc cgtgattatt ggagccatgt
      661 taatctctcc tttgatgaca cctattctgg gagtggggct ctctctagct atatttgatt
      721 ttaaattgtt aagaaaatct tttaaaatat tagctattca aattcttgcc agtctaatag
      781 cttcaacact ttatttttat ctttctccca tttcgtatgc tagttcggag attgttgcta
      841 gaacctctcc gactatttgg gatgttctca ttgcttttgt aggagggata gcaggtatta
      901 ttggtgctag gaaaaaagag accaataata ttgttcctgg tgttgctatt gcaaccgcct
      961 tgatgcctcc tctttgtaca gtaggttatg ctattgcttc tgctaatcta aaatttatca
     1021 taggctcctc ttacctattc ctcatcaatt gtagctttat tgtcattgcg acttatatag
     1081 gtgttaggtt gatgatggtt aagaaacatt attttaaaga taatgaagaa gactctaaaa
     1141 tgcgtaggat tttgcttcta gttgctgttt tgctgatgat tccgagtttc atctctgcaa
     1201 cgactttagt gagagaaacg ttgaaaaaag agtcccttaa gaaatttata tcagagcagt
     1261 ttcaggggta taatattttg aaaaaaacct attctaaaaa gactcatacc ctaaagctaa
     1321 ccatttcagg aaattatttg acagaagaag aactcgatat gatttcaagt aagagaggtg
     1381 actatggttt aagtgatgtt tctgttcaag tttcacaatt gtctgattca gaacaactta
     1441 gtaaggaaga gctggtggag tatttcttcc agtatatcaa ggataaggaa gcaaaagaaa
     1501 aggagaaagc caataaattt gatacagagt ctgaggagca ataatttctt gagaatagct
     1561 ggtttctctc gtgagtcttc tatgtatatc aaaggaagac tgaggtttta agtataaaac
     1621 ttttcttcta ttatagtagc taagtcttga cagggttcaa aaaatggttt acactttata
     1681 aagtttatta ctttgaaaag gtgtgatact gtggctacgg caacaaaaaa gaaaaaatca
     1741 acagttaaaa aaaatctagt catcgtggag tcgcctgcta aggccaagac gattgaaaaa
     1801 tatctaggca gaaactacaa ggttttagcc agtgtcgggc atatccgtga tttgaagaaa
     1861 tccagtatgt ccgtcgatat tgaaaataat tatgaaccgc aatatatcaa tatccgagga
     1921 aaaggccctc ttatcaatga cttgaaaaaa gaagctaaaa aagctaataa agtttttctc
     1981 gcgagtgacc cggaccgtga aggagaagcg atttcttggc atttggccca tattctcaac
     2041 ttggatgaaa atgatgccaa ccgtgtggtc ttcaatgaaa tcaccaagga tgcagtcaaa
     2101 aatgctttta aagaacctcg taagatcgat atggacttgg tcgatgccca acaagctcgt
     2161 cggatcttgg atcgcttggt agggtattcg atttcgccta ttttgtggaa gaaggtcaag
     2221 aagggcttgt cagcaggtcg cgttcagtcc attgccctta aactcatcat tgaccgtgaa
     2281 aatgaaatca atgccttcca gccagaagaa tactggacag ttgatgctgt ctttaaaaag
     2341 ggaaccaaac aatttcatgc ttccttctat ggagtagatg gtaaaaagat gaaactgacc
     2401 agcaatgacg aagtcaagga agtcttgtct cgtctgacta gtaaagactt ttcagtagat
     2461 caggtggata agaaagagcg caagcgcaat gctcctttac cctataccac ttcatctatg
     2521 cagatggatg ctgccaataa aatcaatttc cgtactcgaa aaaccatgat ggttgcccaa
     2581 cagctctatg aaggaattaa tatcggttct ggtgttcaag gtttgattac ctatatgcgt
     2641 accgattcga ctcgtatcag tcctgtagcg caaaatgagg cggcaagctt cattacggat
     2701 cgttttggta gcaagtattc taagcacggt agcaaggtca aaaacgcatc aggtgctcag
     2761 gatgcccatg aggctattcg tccgtcgagt gtctttaata caccagaaag catcgctaag
     2821 tatctggaca aggatcagct caagctatat acccttatct ggaatcgttt tgtggctagc
     2881 cagatgacag cggccgtttt tgataccatg gctgttaaat tgtctcaaaa tggagttcaa
     2941 tttgctgcca atggtagtca ggttaagttt gatggttatc ttgccattta taatgattct
     3001 gacaagaata aaatgctacc agatatggct gttggagatg tggtcaaaca ggttaatagc
     3061 aaaccagagc aacatttcac ccaaccgcct gcccgttatt ctgaagcaac actgattaaa
     3121 accttagagg aaaatggggt tggacgtcca tcaacctatg cgccaaccat tgaaaccatt
     3181 cagaaacgtt attatgttcg cctggcagcc aaacgttttg aaccgacaga gttgggagaa
     3241 attgtcaata agctcatcgt tgaatatttc ccagatatcg taaacgtgac cttcacagct
     3301 gaaatggaag gtaaactgga tgatgtcgaa gttggaaaag agcagtggcg acgggtcatt
     3361 gatgcctttt acaaaccatt ctctaaagaa gttgccaagg ctgaagaaga aatggaaaaa
     3421 atccagatta aggatgaacc agctggattt gactgtgaag tgtgtggcag tccaatggtc
     3481 attaaacttg gtcgttttgg taaattctac gcttgtagca atttcccaga ttgccgtcat
     3541 acccaagcaa tcgtgaaaga gattggtgtt gagtgtccaa gctgtcatca gggacaaatt
     3601 attgagcgaa aaaccaagcg taatcgcctc ttctatggtt gcaatcgcta tccagaatgt
     3661 gaatttacct cttgggacaa gcctgttggt cgtgactgtc caaaatgtgg caacttcctc
     3721 atggagaaaa aagtccgtgg tggtggcaag caggttgttt gtagcaaagg cgactacgag
     3781 gaagaaaaga ttaaataaga ggaggggtcc gaaagtaaat ttcaggctcc ttttggttag
     3841 aacttgacaa aatacatcat tttatgcgaa actagaagaa gattatttta actaggagaa
     3901 gttatgcgtc ttatctatct gataattggt tttttatcac tggccttggc tattgttggg
     3961 gttgttttac ccttgttgcc gacaacgcct ttccttttgt tgtctattgc ttgtttctcc
     4021 agaagttcca agcgtttcga agactggctt tatcatacca agctctatca aacatatgta
     4081 gctgattttc gcgagactaa gtctattacg cgtgaacgaa agaaaaaaat catcgtctct
     4141 atctacgtct tgatgggaat ttctatttat tttgcccctc ttttaccagt caaaattggt
     4201 ctgggtgctt tgaccatctt tatcacttat tatctcttca aggtcattcc agacaaagaa
     4261 tagttaaaac agtagttatt tcccttgata aaattgaaag catattcata acaatatgat
     4321 ataataaatt tgaagtaata ttcaaggaga atcaaatgat ttacgaattt tgtgctgaaa
     4381 atgtgacctt gcttgaaaaa gcgatgcagg ctggagctcg tcggattgaa ctctgtgata
     4441 atctagcagt tggtgggaca acacccagct atggagtgac taaggcagcg gttgaactgg
     4501 cagctaacta cgatacaacc atcatgacca tgattcggcc acgtggtggt gactttgtct
     4561 ataatgacct agaaattgct atcatgctag aagacatttg tttgactgct caggctggaa
     4621 gtcaaggggt tgtatttgga gctttaactg ctgataaaaa gttggataag cctaatctgg
     4681 aaaagttaat tgctgcatca aaaggaatgg aaattgtctt tcacatggcc tttgatgaac
     4741 taagtgatga agatcaaccg gaagctattg actggctcag tcaagccggt gtcactcgta
     4801 tcctaactcg tgctggtgtg tctggcgact ccttagaaaa acgttttgtt cactatcaca
     4861 gaattttgga gtacgctaaa ggtaaaattg aaattctacc aggtgggggg attgaccttg
     4921 acaaccgtca aacctttatt gaccaggtgg gggtaacaca attgcatggt actaaggttg
     4981 ttttttaaaa aatagaaagg aactgctagc cttgggtagc agttttcact tatgtttgaa
     5041 atttttaaat cctatcaatt taatcaagaa aaggctcatg attatggttt tatagaaaat
     5101 agcgaagtct ggacatatag ttgccagatt ttgcaaggtg actttgtcat gactgtgtcc
     5161 atcactgctg ataatgtgaa ctttcaagtc tttgaccaag agactggtga cctctatcct
     5221 cacgttcata tggaaagcat gaggggaagt tttgtcggaa atgtccgtga ggcttgtctg
     5281 gagattcttt accagattcg gaaggcttgt tttgatgtgc aagattttat ctgtcatcag
     5341 actaagcgta tcatgactca agttcaggaa aagtatggaa accagttgga gtatctgtgg
     5401 gaaaaatcgc ctgatacagc tgtattgcgc catgaaggca atcaaaagtg gtatgccgtc
     5461 ttgatgaaaa tctcttggaa taagctggaa aagggcagag aaggacaagt ggaagcagtc
     5521 aacctcaaac atgaccaagt agctaatttg ctttcacaaa aggggattta tccagccttc
     5581 catatgagca agcgctactg gattagtgtg tcccttgatg atactttatc agatgaagaa
     5641 gtactggaat tgatagaaaa aagttggaac ttaacctcta aaaaatgaaa tattttaata
     5701 attttcatga actttcaatt agctaaatat tctttactga agaaattttc agaaaatata
     5761 ggatttacca caccagagga atgtggtgcc atcttcaaat acctgattga gaatgtcaag
     5821 acggatcgtc agatcatcta ttcgcctcac tgtcatgatg acctcggaat ggcagtggca
     5881 aatagccttg ctgctgtcaa gaatggtgca ggacgtgttg aagggactat caatggtatt
     5941 agggagcgag ctgaaaatgc tgctttggaa gaaattgcag tggctctcaa tattcgccaa
     6001 gattactacc aagtagaaac cagtattgtc ctaaatgaga ccatcaatac gtcagaaatg
     6061 gtttctcgct tctctggtat tccagttcct aaaaacaaag ccgtcgttgg tggcaatacc
     6121 ttctcccacg aatctggtat tcaccaagat ggagtcctta aaaatcctct cacttatgag
     6181 atcatcacac ctgaattggt tggtgttaag attccgcttg gaaaattatc tggtcgccat
     6241 gcttttgttg agaaactgag agaattggcc ctagatttta cagaagagga tatcaaacca
     6301 ctctttgcta agttcaaggc actggccgat aagaagtaag aaatcacaga tgcagatact
     6361 cgagctttgg tagctggaac catggttgaa aatccagaag gcttccactt tgatgattta
     6421 caacttcaaa ctcatgcaga taatgacatt gaagcgctcg ttagcctagc caatatggat
     6481 ggtgagaaag tcgaatttaa tgcgacaggg caaggttccg ttgaagcaat ctttaatgct
     6541 atcgataagt tctttaacca atctgttcgt ttggtgtcct acactatcga tgcggtaaca
     6601 gatggaatcg atacccagga tcgggttttg gtcactgttg aaaacagaga tacagaaacc
     6661 atctttaatg cagcagggct tgattttgat gtgttgaagg cttctgctat tgcctatata
     6721 aacgctaata cctttgttca aaaagagaat gcaggtgcag tgtttcttac cacgatatgc
     6781 ctagtgtgta aaggagaagg ctatggcaaa gaaaatagta gctctagtag gagacggaat
     6841 tggcccagaa atcatggagg ctggtttaga agttctggag gctctagctg aaaaaacagg
     6901 ttttgactat gagattgaca gacgaccgtt cggaggtgca gatattgatg cagcaggacc
     6961 tcccttacct gatgaaaccc ttaaggcaag tagggaagca gatgctatcc tactagtagc
     7021 tatcggtagt cctcagtatg atggagtagc ggttcgccct gaacaaggcc tgatggctct
     7081 ccgtaaggaa ctcaatcttt acgctaatat tcgtcctgta aaaatctttg acagtctcaa
     7141 gtatttgtca ccactcaaac cggaacgaat ttctggtgta gactttgtcg tggtgcgtga
     7201 attgacaggc gagatttact ttggagatca tattcttgaa gagcgcaaag cgcgtgatat
     7261 caacgactat agctatgagg aagtggagcg gattattcgc aaagcctttg aaattgcaag
     7321 aaatcgcaga aaaatcgtta ctagtatcga taagcaaaat gttctagcga cctcaaaact
     7381 ctggcggaaa gtagctgagg aagtcgcaca ggatttccca gatgtaacct tggaatatca
     7441 gctggtagac tcagctgcta tgcttatgat taccaatcct gctaagtttg atgttattgt
     7501 aacggagaat ctttttggag atattttatc tgatgaatca agcgtcttat ctggtacact
     7561 tggggttatg ccatcagcca gtcattctga aaatggacca agtctctatg aacctattca
     7621 cggttcagca cctgatattg caggtcaagg aattgccaat cctatttcca tgattttatc
     7681 agtttccatg atgttgagag atagtttcgg acgttatgag gatgcagagc gtatcaaacg
     7741 tgctgttgag acaagtctgg cggcaggaat tttaacgaga gatataggag gtcaggcttc
     7801 aacaaaggaa atgacggaag ctattattgc aaggttatga agttagacga aaaaattact
     7861 ctagtccttt tgatttggaa tgtcatcatt ttcttgattt atggtattga caaatctaag
     7921 gcaaggagaa gagtttggcg catccctgag aaaatcttac ttattttagc ctttactttt
     7981 ggtggttttg gtgcctggct agcaggaatc atctttcacc acaagactcg aaaatggtac
     8041 tttaaaatag tttggtttct tgggatggtg accacactag tagccttata ttttatttgg
     8101 aggtaatgga tggcagggtc ttcgagggaa tacgctgctt gggctctagc ggactatggt
     8161 tttaaggtcg tgattgcagg atctttcggt gacattcatt acaataatga actcaataat
     8221 ggcatgttgc caatcgttca gcctagagag gttagagaga aactagccca gctaaaacca
     8281 accgaccagg taactgtgga cttggaacaa caaaaaatca tctcaccagt tgaagaattc
     8341 accttcgaga tagatagcga gtggaaacat aaactcctaa atagtttgga tgatatcggt
     8401 attaccttgc agtatgaaga gttgattgct gcttatgaaa aacaacgacc agcctactgg
     8461 caggattaga aaaaatagaa aaggagatat agtaaactga aataagatgt aaacaaatga
     8521 attggagctt aacatccatt tccagcaatt ttttagaaac tacagtggac tattctggat
     8581 tcaacacatt ataaaattat gacaaaacac attcacaaga aggctacgac attttaaaag
     8641 gtgagggcgg atgtatcgtt tgccctacta aagttggtta cattatcatg accagtgaca
     8701 aggcaggact tgagcgtaag ttcgcagcca aagaacgtaa gcgtaacaaa ccaggtgttg
     8761 ttctctgcgg tagcatggat gaactttgcg ctttagcgca actcaaccca gaaattgaag
     8821 cattctacta aaaacattgg gatgaagata ttcttcttgg ttgtatcctt ccttggaaac
     8881 cagaagcctt tgaaaaactc aaagcatacg gggatggccg tgaagaactt attactgatg
     8941 tacgtggtac tagctgtttt gttatcaagt ttggaaaagc aggtgaacaa ttggctgcca
     9001 agctttggga agaaggtaaa atggtctacg cctcatctgc ttcaatgaca aaacgattga
     9061 aactcgctat gagcaaggtg taatggtgtc tatggtcgat aaggacggca aactcatccc
     9121 agaacaagga ggagcacgtt caacttcacc agctccagtt gtgatccgta aagggcttga
     9181 cattgataaa atcatgatgc acctgtcaga tacttttaac tcatgggact accgtcaggt
     9241 tgagtattat taggatagag aagaagtcta gtgttatgag atattaaagc tcctaacact
     9301 gggcttttgt ttagaatttc ttttcttttt ctataggata tggtattcta tgtagaaaat
     9361 atatgttaat aagtaatgcc aatatttaaa catcattagt aaaaggagtt agattgatga
     9421 ataaaagaaa agttagttta gaagattttt ataaatggta tagtctaaat aaagaagagt
     9481 tattaaataa ggcaactgtt ggtgaaaagt ttaatgataa attaaaagaa gagtttctcc
     9541 aggaatggcc tttggatagg attttaacaa tgtcaatcga tgaatatgta ataggaaagg
     9601 gacagcaaaa taagtcttta tgctacgctc ttgagaaggg aaaatacaaa aatctatttc
     9661 ttggaatttc tggtggctca gcttcaaaat ttggtattta ttggaataaa aaaacaaaca
     9721 aatataaaga tcaagctaat aatgagattt cagagttgga tcagcgattt tcaaaattaa
     9781 aatcagattt gtatgaaatt atcaaagaag gtattcgttt taactttgaa aatcctattt
     9841 ttgatatgaa aagatcaaca aatgaattta ttggtcgttc tgctatggtg acaaaattac
     9901 tttgtatcta tactgaggga gatcctttct ttggtgtaaa tattaatagt cagaaagaat
     9961 tttggaacca ctttgtttct cagacaaatc aaggtggacc ttatctgcaa aatcataaaa
    10021 taattgaact ggtgtccaaa acttatcctg agttggagcc atcgaaatta ggaactatgc
    10081 tttttgagta ttctaagctt tttatggaaa ataaggaaga caatagtaca atggattcat
    10141 caaacaattt tagtcatcaa ttaactcaat ctctattaaa gtctccaaac cttatccttc
    10201 gtggtgctcc tggcacagga aagacttatc ttgctaaaga aattgccaaa gaattaacgg
    10261 atggcaacga agaccaaatc ggatttgtac aatttcaccc atcatatgat tatacggatt
    10321 ttgtagaagg tttaagacca gtatcaaatg gggatggagc tattgagttt aggctacagg
    10381 acggtatttt taaagatttt tgtcagaaag caaaagaaac ccaattgatt ggaggacaag
    10441 ataattttga tgaggcttgg gattcttact tagaatatat aaatgttgct gaagaaaaag
    10501 aatatataac aaaaacatct tacttatctg ttaatagtag acaaaattta tcagtaaatt
    10561 atgatagtgg tgttccagga tggtcactac ctagcaaata tgtttacgag ttgtataaag
    10621 ataaaaatta taataagcaa gaatactaca aaagtggtgg aaaaactgtc ctagaaacat
    10681 tgagaaagag atttggtttg aaagactatg tttccccaac agaaattgat actgataaga
    10741 aattcgtttt catcatcgat gaaatcaatc gtggggagat ttctaagatt tttggcgaac
    10801 tctttttctc tatcgaccct ggctatcgtg gtgaaaaagg aagtgtttct acccaatatg
    10861 caaatctaca cgaaactgat gaaaagttct atatccccga aaatgtttac atcatcggaa
    10921 ctatgaatga tattgatcgt tcagtggata cctttgattt tgctatgcgt cgtcgttttc
    10981 gttttgttga agttactgcc gagggtcaag ttggcatgtt ggataaagag ctgaatatcc
    11041 atgcagaaga agcaaaaatt cgtctaagaa acttgaacgc tgctatcgaa aatgttcagg
    11101 aattaaacag tcattatcat attggaccaa gttattttct taagttgaag gatgtagatt
    11161 ttgactatga attactctgg tctgattata ttaagcctct cctagaagac tacttgcgag
    11221 gttcttatga tgaggttgaa actttggaaa ctttgaaaaa agcatttgaa ctgacaaata
    11281 atgatcaaac tggtcaacaa gatactggtg ataatgatgc ggataactga taatcagcat
    11341 aaaattgcta aagaagactt tgtcgcagaa tatcccaaac taagtcaagc tcttcttgat
    11401 agaacactgg ataacctttc tagagaggat aatatcttta tttttccaaa tgatttgact
    11461 catactcctg atttggataa ggaccaaaag atttttgaaa cagtcaatca gaaaatcaag
    11521 acagggaacg tgattggttt tcttggatat ggtcaggaaa gattaacgat ttcctcacga
    11581 ttttctgatg agagtaatga ccattttttg cattatctct taaacaaggt tcttcatatc
    11641 aatctcacta gtttagatgt tgctttgtct cgtgaagaga ggctttatca acttttgatg
    11701 tatctcttcc ccaagtatct acaagctgct attcgaaaag gtctttataa ggaatatcat
    11761 cgattttctc ataacgacag tcatgttaag ggagtaattg atgtaagaaa ccatctcaag
    11821 aaaaatcttc ctttcacggg aaatattgcc tacacaacga gagagttcac ctatgataat
    11881 cccctcatgc agttggtccg tcacactatt gaatgcatta agaatcagaa aagcattggt
    11941 caaggggtac tagataatct ctcaactagt cgtgaaaacg tatctgaaat cgtgcgtgta
    12001 acgccctctt ataaactagc tgatcgtgct aagattatca gaatgaataa aatcaaactt
    12061 atccgacacg cctatttcag agagtataga aaattacagg aactctgctt ggtgattctg
    12121 agtagagaaa agcatggtct tggacctcaa gcccaaaggg tacatggtat tctctttgat
    12181 gttgcctggc tttgggaaga gtatgtttac accttgttgc caaaaggttt tgtacatccc
    12241 agaaataagg ataagacgga tggaatttca gtattttctg ttgggaaacg aaaagtatat
    12301 ccagattttt atgatagaga acgaaagatt gttctagatg caaaatataa aaaactggaa
    12361 ttgactgaaa aaggaatcaa ccgtgaggac ttattccagc tgatttccta ttcttatatt
    12421 ttaaaagctg agaaggctgg acttgttttt ccgagcaagg acaaggttat tgataatgag
    12481 ataggaaacc tagcaggtta tggtctattc gaatccctca gaatgcctca ttctatagta
    12541 cattttgtaa aatgatggaa aattcagaag aaaattttaa agcgattatt gatgaagaag
    12601 tggggagaaa ataatttccc ctctttcttt tatttttaac acaagtaaaa cccgaacgat
    12661 atattttaat tcataaaata atttgacaaa aactgtactt tggtttataa tgaattaagg
    12721 aaacgtcgga aaaggcgtag tgatgcaaga gcataggtag gtcattacaa aagaaacgag
    12781 acatcgatat gttaaatgaa tttccaattt ttgattacga agatattcaa ttgattccaa
    12841 ataaatgtgt cattaaaagc cgtgcagaag cggatacaag tgtcacttta ggaaatcaca
    12901 cctttaaact acctgttgtg ccagcgaata tgcagacgat tttggatgaa aatgtagcag
    12961 agcaactggc taaaggtggt tacttctaca ttatgcaccg ttttgatgag gcaggacgca
    13021 ttccttttat taaacgaatg cacaatcaag ggctcattgc ttccatatct gtcggtgtta
    13081 aggactatga gtatgatttc gttagacagc tcaagactga tgctcctgag tatatcacta
    13141 ttgatattgc tcatggtcat gcggatagcg tgatttctat gattcaacac atcaagaaag
    13201 aattgccaga tacctttgtc attgctggaa atgtgggaac accagaagct gtgcgtgaat
    13261 tggaaaatgc tggtgcagat gctactaagg tcggaatcgg tcctggtaag gtttgtatca
    13321 ccaaggttaa gactggtttt ggtacaggtg gttggcagtt ggctgctcta cgctggtgtg
    13381 ccaaggctgc gcgtaaaccg attatcgctg atggaggaat tcgtactcac ggtgatattg
    13441 ccaagtctat ccgcttcggt gctagcatga tcatgattgg ttccctcttt gcaggacata
    13501 ttgaaagtcc agggaaaacg attgaagtcg atggtgaaca gttcaaagaa tattatggtt
    13561 cagcctcaca atatcaaaaa ggtgcttaca aaaatgtgga aggcaaacgt atcttgcttc
    13621 ctgctaaagg tcatctgcaa gacactttaa ctgagatgga acaagacctt caaagtgcta
    13681 tttcttatgc aggtggacgt caggttgctg accttaaaca cgttgattat gtgatcgtga
    13741 aaaactccat ctggaatggg gatgcttccc actaagacgg ggtctttgac caaaaaactt
    13801 gttattagag caaatttctg ttataataaa acaagtttcc acccttagtg taatggatat
    13861 cacgtaagat tccggttctt gagatggggg ttcgattccc tcagggtgga tgtaaacatc
    13921 ctaaaaagcc tttaataggg cttttttctt tatcctgacc caaatttgcc gctaaaactg
    13981 agaatctctg tctaaagaat tcccaaatgc tttccagtcc cgttttagag tgactcaggg
    14041 ggcttttttt gatataataa aaaggactgt tatcagttag aaagaggttg gtatgaaaga
    14101 attacaaact gtactaaaga accattttgc aatcgaattt gcagacaaaa atttactgga
    14161 aactgccttt actcatacga gttatgccaa tgagcaccgc ctcttaaaaa tttcacacaa
    14221 tgaacgcttg gaatttttag gagacgctgt tctacagtta ttgatttcag aatatctata
    14281 taaaaaatat cctaaaaagc ctgaaggtga cctatcaaaa ctccgtgcta tgattgtccg
    14341 tgaggagagt ttggctggct ttgcgcgtga ttgccagttt gaccagttta tcaagctggg
    14401 taagggggaa gaaaaatctg gtgggcgcaa tcgtgatacc attcttggtg atgcctttga
    14461 agcctttctt ggtgcccttc ttttggacaa ggatgtggcc aaggtcaagg aatttatcta
    14521 tcaagtcatg attcctaagg ttgaagcagg cgaatttgag atgattacag actataaaac
    14581 ccatctccaa gagttgcttc aggtcaatgg tgatgtggct attcgttatc aggtgatttc
    14641 tgaaacgggt cctgctcacg ataaggtctt tgatgtagaa gttcttgttg aaggtaagag
    14701 catcggtcaa ggtcaaggtc gttctaagaa attagcagag caggaagctg ccaaaaatgc
    14761 cgttgagaaa gggctggatt catgtattta aaggaaatcg aaattcaggg attcaagtct
    14821 tttgctgata agaccaaggt cgtctttgac caaggtgtga cggcagtcgt tggacccaat
    14881 ggatctggaa agtcgaatat tacagaaagt ctgcgatggg ccttgggaga gtctagtgtc
    14941 aagagtctcc gtgggggcaa gatgccggat gtcatctttg ctggaacaga aagtcgtaaa
    15001 ccgcttaatt atgcttctgt agttgtgact ctggataatc atgatggatt tatcaaggat
    15061 gcaggtcaag aaatcagagt agaacgccat atctatcgta gtggggatag tgaatacaaa
    15121 attgacggca agaaagttcg tcttcgtgat attcatgttc tcttcttgga cacaggtttg
    15181 ggacgagatt ccttttccat catttcccaa ggcaaggttg aggagatttt taattctaag
    15241 cctgaggaac gccgagctat ttttgaagaa gctgcaggag ttttaaaata caagactcgt
    15301 agaaaagaaa ctgagagcaa attgcaacaa actcaggata atctggaccg cttagaggac
    15361 attatctacg agttggataa tcaaatcaag cctcttgaga agcaagctga gaatgcccgt
    15421 aagtttttag acttggaagg acaacgtaag gctatttatt tagacgtgct ggttgctcaa
    15481 atcaaggata ataaggctga actagactcg acagaagaag agttggctca ggttcaggaa
    15541 ctcttgacta gttattacca aaagcgtgaa aaattagaag aggaaaatca aactcttaaa
    15601 aagcaacgcc aagatttgca ggctgaaatg gccaaagacc aaggcagttt gatggatttg
    15661 accagtctga ttagtgactt agagagaaaa ttagccctat cgaaactgga atctgagcaa
    15721 gtagccctca atcaacagga agcacaagcc cgtttggcta ctttggagga taagagaagt
    15781 tcactcagcc aagaaaaatc tgataaagaa agctctttag ctctgttaga gggaaatcta
    15841 gtccaaaata atcaaaaact caatcgttta gaagctgaat tgctggcttt ctcagacgat
    15901 cctgatcaga tgattgagct cttacgtgaa cgctttgtag ctcttttaca agaagaagcg
    15961 gatgtctcaa accagttgac ccgtattgag aatgagttgg aaaatagtcg tcagctttct
    16021 caaaaacaag cagatcaact agaaaagctg aaagagcaat tggctatagc taaagagaag
    16081 gctagtcagc aaaaggaaga gcttgaaact gccaaggagc aggttcagaa attattggct
    16141 gactaccaag ctattgccaa ggagcaagag gagcagaaaa cttcctatca agctcaacaa
    16201 agccaactct ttgaccgtct ggataatctc aaaaacaagc aggccagagc tcaaagtttg
    16261 gaaaatatcc tgagaaatca tagtaacttt tatgcaggtg ttaagagtgt tctccaagaa
    16321 aaagatcgcc taggtgggat tattggtgca gtcagtgagc atctgacctt tgatatgcat
    16381 tatcaaactg ccctagaaat tgcacttgga gcgagtagtc agcacattat tgtagaagat
    16441 gagaatgcgg caaccaaagc cattgatttc ctcaaacgaa acagagccgg tcgtgcaacc
    16501 tttcttcctt tgaccactat taaggcgcgt acgatttcta gtcagaacca agatgctatc
    16561 gctgtaagcc caggtttcct tgggatggca gatgagttag ttactttcga tactagactg
    16621 gaagccattt tcaagaactt gctagctacg acggctatct ttgataccgt agaacatgcg
    16681 cgtgaagctg ctcgacaagt tcgttatcag gttcgcatgg tgacattgga tgggacagag
    16741 cttcgtacag gtggttccta tgcaggtgga gccaatcgtc agaacaacag catcttcatc
    16801 aagccagaac tggagcaatt acaaaaagaa attgctgaag aagaagcaag cttggattca
    16861 gaagaagtgg ctttgaagac cttgcaagat gagatggcca gattgaccga gtcattagaa
    16921 gctattaaat ctcaaggaga gcaggcacgt attcaggagc aaggcttgtt cctcgcttat
    16981 cagcaaacta gtcagcaagt tgaagagcta gaaactcttt ggaaactcca agaagaggaa
    17041 atagatcgtc tttccgaggg agattggcaa gcggataagg aaaactgcca agagcgtctt
    17101 gctgcaatcg ccagtgacaa gcaaaatctg gaagctgaga ttgaagagat taagtctaac
    17161 aaaaatgcca tccaagaacg ctatcaaaac ttgcaggaag agctagcgca agctcgtttg
    17221 cttaagacag aactgcaagg gcaaaaacgt tatgaagttg ctgatattga gcgtttaggc
    17281 aaggaattgg ataatcttaa tatcgaacaa gaagaaatcc agcgcatgct ccaagaaaaa
    17341 gttgacaatc ttgagaaagt tgatacggat ttgctcaatc agcaggccga agaagccaaa
    17401 actcagaaaa caaatctcca acaaggtttg attcgcaagc agtttgagtt ggatgatatt
    17461 gaagggcagc tggatgatat tgctagtcat ttggatcagg ctcgccagca gaatgaggag
    17521 tggattcgca agcaaacacg tgctgaagct aagaaagaaa aggtcagcga acgcttgcgc
    17581 catctacaaa gtcaattaac agaccagtac cagattagct atactgaagc tctagaaaaa
    17641 gcgcatgaat tggaaaacct caatctggca gagcaagaag ttaaggattt agagaaggct
    17701 attcgctcac tgggtcctgt caatatagaa gctattgacc agtacgaaga agtttacaac
    17761 cgtctggact ttctaaatag tcagcgagat gatattttgt cagcgaaaaa tctgctcctt
    17821 gaaaccatta cagagatgaa tgatgaggtt aaggaacgct ttaaatcaac ctttgaagct
    17881 attcgtgagt cctttaaagt gacctttaag cagatgtttg gcggaggtca ggcagacttg
    17941 atattgactg agggcgacct tttaacagct ggtgtggaga tttctgttca acctccaggt
    18001 aagaaaatcc agtcgcttaa cctcatgagt ggtggtgaaa aagctctatc ggctcttgcc
    18061 ttgctcttct ccattattcg tgtcaagact attccatttg ttatcttgga tgaggtggaa
    18121 gctgcgctgg atgaagctaa tgttaaacgt tttggggatt acctcaaccg ctttgacaag
    18181 gacagccagt tcatcgtcgt aacccaccgt aagggaacca tggcagcggc tgattctatc
    18241 tatggagtga ccatgcaaga atcaggtgtc tcaaaaattg tttcagttaa gttaaaagat
    18301 ttagaaagta ttgaaggatg acaattaaac tagtagcaac ggatatggac ggaaccttcc
    18361 tagatgggaa tggacgcttt gatatggatc gtctcaagtc tctcttggct tcctacaagg
    18421 aaaaagggat ttactttgcg gtggcttcgg gtcggggatt tctgtctctg gaaaaattat
    18481 ttgctgatgt tcgtgatgac attattttca tcgcggaaaa tggcagtttg gtagagtatc
    18541 aaggtcagga cttgtatgaa gcgactatgt ctcgtgactt ttatctggca acttttgaaa
    18601 agctgaaaac gtcaccttat gtagatatca ataaactgct cttgacgggt aataagggtt
    18661 catatgttct agatacggtt gatgagacct atttgaaagt gagtcagcat tataatgaaa
    18721 atatccaaaa agtagcgagt ttggaagata tcacagatga cattttcaaa tttacaacca
    18781 acttcacaga agaaacgctg gaagatgggg aggcttgggt aaacgaaaac gttcctggtg
    18841 ttaaggctat gacaactggc tttgaatcta ttgatattgt tctggactat gtcgataagg
    18901 gagtggccat tgttgaatta gttaaaaaac ttggtatcac aatggatcag gtcatggctt
    18961 ttggagacaa tcttaatgac ttacatatga tgcaggttgt gggacatcct gtagctcctg
    19021 aaaatgcacg acctgaaatt ttagaattag caaagactgt gattggtcac cataaggacc
    19081 agtcggttat agcttatatg gagggcttat aatggcagat ataaaattaa tcgcattgga
    19141 cttggacggg accttgctga ctactgataa aaggctgacg gatcgtacca aggaaacctt
    19201 gaaagctgcg cgtgatcgtg gtatcaaggt cgtattgaca actggtcgtc ccttaaaagc
    19261 tatggatttc tttctccatg agctagggac tgacggtcag gaagatgagt ataccattac
    19321 ttttaatggt ggtttggttc agaaaaatac aggtgaaatc cttgataaga cagtcttttc
    19381 atatgatgat gtggcacgct tgtatgaaga aacagagaaa ttatcactgc ctcttgacgc
    19441 tatctcagaa ggaactgttt atcaaattca atcggaccaa gaaagtcttt atgccaaatt
    19501 caatccagct ttgacttttg ttccagttga ttttgaagac ctgtctaatc aaatgaccta
    19561 caataaatgc gtgaccgcct ttgctcaaga acccttggat gcagccattc agaagatttc
    19621 tccagaattg tttgaccaat atgaaatctt taaatcacgt gaaatgttgc tagaatggtc
    19681 accaaagaat gttcataaag caacaggttt ggcaaaacta attagccatc ttggaattga
    19741 tcaaagtcaa gtgatggcct gtggtgacga ggccaatgac ctctctatga ttgaatgggc
    19801 agggctcggt gttgccatgc aaaacgctgt tcctgaagtc aaggcagtcg caaatgtggt
    19861 aactcctatg accaatgatg aagaagctgt cgcctgggct atcgaagaat atgtgctaaa
    19921 ggagaactaa gatatgggat tgtttgaccg tctattcgga aaaaaagaag aacctaaaat
    19981 cgaagaagtt gtaaaagaag ctctggaaaa tcttgatttg tctgaagatg ttgatcctac
    20041 cttcacagaa gttgaggaag tttctcagga agaagcagag gttgaaattg ttgaacaagc
    20101 tgtgttccaa gaagaggaaa tccaagacac agttgaagaa agtctggatt tagagccagt
    20161 tgtagaagtt tctcaaaaag aagtcgaaga atttccacac tcagaagaag ggaatactga
    20221 gtttctagag actgtagaag aaaataattc tgaaattctt gaagcagaaa ggcctcaaac
    20281 agaagaaact gttcaggaaa aatatgaccg cagtcttaag aaaactcgca caggtttcgg
    20341 tgcccgcttg aatgccttct ttgctaactt ccgctctgtt gacgaagaat ttttcgagga
    20401 actggaagaa ctgttgatta tgagtgatgt tggtgtccaa gtcgcttcta acttaacgga
    20461 ggaactacgt tacgaagcca agcttgaaaa tgccaagaaa cctgatgcac ttcgtcgtgt
    20521 catcattgag aaattggttg agctttataa aaaggatggt agctacgatg aaagcatcca
    20581 cttccaagat aacttgacag ttatgctctt tgttggtgtg aatggtgttg ggaaaacaac
    20641 ttctatcgga aaactagccc accgctacaa acaagctggt aagaaggtca tgctggttgc
    20701 agcagatacc ttccgtgcgg gtgcagtagc tcagctagct gaatggggcc gacgagtaga
    20761 tgttccagta gtaactggac ctgaaaaagc tgatccagcc agcgtggtct ttgatggtat
    20821 ggaacgtgcc gtggctgaag gtatcgatat tctcatgatt gatactgctg gtcgtctgca
    20881 aaataaggat aaccttatgg ctgagttgga aaagattggt cgtattatca aacgtgttgt
    20941 gccagaagca ccacatgaaa ccttcttggc acttgatgca tcaacaggtc aaaatgccct
    21001 agtacaggcc aaagaatttt cgaaaatcac acctttaacc ggaattgttt tgactaagat
    21061 tgatggaact gctcgaggag gtgtggttct agccattcgt gaagaactca atattcctgt
    21121 aaaattgatt ggttttggtg aaaaaatcga tgatattgga gagtttaact cagaaaactt
    21181 catgaaaggt ctcttggaag gtttaatcta atcagaagca aaaatcctgg gctctttgtc
    21241 aactgtagtg ggttgaagtc agctaagctc gagaaaggac aaatttcgtc ctttctt
//
LOCUS       DAVEHY010000041        21071 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVEHY010000041 DAVEHY010000000
VERSION     DAVEHY010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.041"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            331..582
                     /locus_tag="VUZ44_001785"
     CDS             331..582
                     /locus_tag="VUZ44_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320654.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            811..1113
                     /locus_tag="VUZ44_001786"
     CDS             811..1113
                     /locus_tag="VUZ44_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320655.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYGEDFLI"
     gene            1110..2468
                     /locus_tag="VUZ44_001787"
     CDS             1110..2468
                     /locus_tag="VUZ44_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HEU0320656.1"
                     /translation="MNYEKYLNYLDYETEIEDAYHNLLLEYKISDNFSDNFSDEHWLY
                     NLPSNITQSKGFKIHLSASILNANLVAKKFFDFIFSREKKINFKILVSIKELSLQNTG
                     LNGYSQVGKFITIYPKDNKEFQRLLHKLEILYKGVKGVNIPSDFRFQLSEVVYYRYGE
                     FVKDSTFKDKRDKKIPSNVNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNT
                     QKRVYSLLKEASDLSLVDFTNRDSVNRLINEREILVELEKEEFTPKVFNDFYIKNSYF
                     VEFEFIIADKLSEYNMVSGSYDWFLTLIDYMEIINSKYNLSYRDLSFNNILIDNRNNI
                     YIIDFEHALRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIMGLVLLLYWSQNLDD
                     FNVFSKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYKYDTFSELKKDFIEV
                     LK"
     gene            2482..3399
                     /locus_tag="VUZ44_001788"
     CDS             2482..3399
                     /locus_tag="VUZ44_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320657.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            3396..4196
                     /locus_tag="VUZ44_001789"
     CDS             3396..4196
                     /locus_tag="VUZ44_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320658.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            4354..4827
                     /gene="tnpA"
                     /locus_tag="VUZ44_001790"
     CDS             4354..4827
                     /gene="tnpA"
                     /locus_tag="VUZ44_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEU0320659.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            5084..5305
                     /locus_tag="VUZ44_001791"
     CDS             5084..5305
                     /locus_tag="VUZ44_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0320660.1"
                     /translation="MYRRLRDLREGHDLPQKQIATILSFTNSAYAKIERGEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            5752..6054
                     /locus_tag="VUZ44_001792"
                     /pseudo
     CDS             5752..6054
                     /locus_tag="VUZ44_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            6210..7439
                     /locus_tag="VUZ44_001793"
     CDS             6210..7439
                     /locus_tag="VUZ44_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU0320661.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            7459..10155
                     /gene="ppc"
                     /locus_tag="VUZ44_001794"
     CDS             7459..10155
                     /gene="ppc"
                     /locus_tag="VUZ44_001794"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU0320662.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYETIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    10238..10455
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10568..11572
                     /locus_tag="VUZ44_001795"
     CDS             10568..11572
                     /locus_tag="VUZ44_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU0320663.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGNG
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            11641..12507
                     /locus_tag="VUZ44_001796"
     CDS             11641..12507
                     /locus_tag="VUZ44_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320664.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            12504..13262
                     /locus_tag="VUZ44_001797"
     CDS             12504..13262
                     /locus_tag="VUZ44_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320665.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            13352..15112
                     /gene="dnaG"
                     /locus_tag="VUZ44_001798"
     CDS             13352..15112
                     /gene="dnaG"
                     /locus_tag="VUZ44_001798"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU0320666.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     ANLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            15115..16224
                     /gene="rpoD"
                     /locus_tag="VUZ44_001799"
     CDS             15115..16224
                     /gene="rpoD"
                     /locus_tag="VUZ44_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU0320667.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            16238..16567
                     /locus_tag="VUZ44_001800"
     CDS             16238..16567
                     /locus_tag="VUZ44_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU0320668.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            16682..17725
                     /gene="cpoA"
                     /locus_tag="VUZ44_001801"
     CDS             16682..17725
                     /gene="cpoA"
                     /locus_tag="VUZ44_001801"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU0320669.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            17741..19066
                     /locus_tag="VUZ44_001802"
     CDS             17741..19066
                     /locus_tag="VUZ44_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU0320670.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            19097..19273
                     /locus_tag="VUZ44_001803"
     CDS             19097..19273
                     /locus_tag="VUZ44_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU0320671.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            19332..19466
                     /locus_tag="VUZ44_001804"
     CDS             19332..19466
                     /locus_tag="VUZ44_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU0320672.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            19530..20840
                     /gene="obgE"
                     /locus_tag="VUZ44_001805"
     CDS             19530..20840
                     /gene="obgE"
                     /locus_tag="VUZ44_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU0320673.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            20850..21008
                     /locus_tag="VUZ44_001806"
     CDS             20850..21008
                     /locus_tag="VUZ44_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320674.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         6695 a         3414 c         4482 g         6480 t
ORIGIN      
        1 ggtcctgcga atggtattta tagataggag attatagtca cttaaaaatc aaaaaattat
       61 aaaatttttg ttttacttaa atagatattt tatgatgggc gaagttttta taactagttc
      121 ctataagtac agaaacctat tttaatttac taatttcaaa acaatttttt gagatatatg
      181 taattaaatc taaattaagc tttaaaaaat tatttttagc aatttgattt tgaaagtgtc
      241 atgcagcaat atgaaagcgt agaatagagg tgtttccaat gtacaagtaa gttttgattc
      301 caaataaagt aatagaaaag gagctatata atgagtagtc aaatgaaagc tttcttgaat
      361 gaacttcaag gaaatatgga agttgttgga gaattttttg ataatcctga aaaggtaatt
      421 agaaaatttg gaattgtcgg aagagagaag gaagcattgc taatccgtga cttaaatgat
      481 atggatgatt atgctctttc aattcaaaat agcgttgcat cgccttctgg ggcacatagt
      541 agcacttgcc attttgttag acaagattta caatccgcat aattgttaat atataaaaca
      601 taaaatttca attttcaatt agggataata gaattcctta ctatgatata gaaagtgaat
      661 taattaggaa atcttagtca gaggtttctg attaattcat tttttatata ttaagagtga
      721 tgtgaaatgt tcaaattgtg agactactct cggattgttg tatagaaatt taaaatttta
      781 ttgtgagctt tttaaggaag agtggccgat atgaaaaata aatacgatgt taaaagaatt
      841 attccggatg aattatcaga atcactagat atttttctaa aaaattattc tgaaactgga
      901 ttgtcagatt ataatactta tctcttttat ggttttatct tgaagtccta taaattgcct
      961 cgagaaaata gatatagcat aaaattattg gtgaaggaat tacaaaatag aggactgaaa
     1021 gttacattga ttatcaacat ttattatcac gctttaaatt gtttggcttt aaatgatggt
     1081 ctaaaaattt atggagaaga tttcttaata tgaattacga aaagtattta aactatttgg
     1141 actatgaaac tgaaatagaa gacgcatacc ataatttatt attagaatat aaaattagtg
     1201 ataattttag tgataatttt agtgatgaac attggttata taatttgccg tctaatatca
     1261 cccaatctaa gggatttaaa atacacctga gcgcttcaat attaaatgct aatttggttg
     1321 ctaaaaaatt ctttgatttt atattttcta gagagaagaa gataaatttc aaaattttgg
     1381 ttagcattaa agaactttct ttgcaaaata cagggcttaa tggttattca caagtcggga
     1441 aattcattac aatttatcca aaagataata aagagtttca acgtttgtta cacaaattag
     1501 aaatattgta taaaggtgta aagggtgtaa acataccatc agatttcaga tttcaactta
     1561 gcgaggttgt atattacaga tatggggagt tcgtaaaaga tagcactttc aaggataaaa
     1621 gagataagaa aatcccttca aatgtgaatg ttccaataag ggattactat attccaagat
     1681 ataacactat tcctgatcaa tatattattt tggaagtgat ttctaaaaat gccaaaggtg
     1741 gagtttataa agtatttaat actcaaaagc gagtttattc tttattaaaa gaagctagtg
     1801 atttatcgtt ggttgatttt acaaatagag attctgtgaa tcgtttaata aatgaaagag
     1861 aaatattagt agaattggaa aaggaggaat ttactccaaa agtttttaac gatttttaca
     1921 taaagaattc gtattttgtg gaatttgagt ttattattgc agataaatta agcgagtata
     1981 atatggttag tggctcgtat gattggtttt taacattaat tgattatatg gagataataa
     2041 actccaaata taatctttcc tatagagatt tatcatttaa taatatactt attgataata
     2101 gaaataatat ttatattata gactttgagc atgccctaag gaaagaaact caaattgaag
     2161 aaaaaaagtt gcctctattt ggaactccag ggttttatga aaccaactta aatttattga
     2221 ataatcaacc agaggatatt atgggattgg ttttgttatt atattggagt cagaatttag
     2281 atgattttaa cgtcttttca aaaatgagtt ttttagaagc gatggagtat gcaatgaatt
     2341 ttaattcgcg tcgcttagac acacttgata aatcagattg gctttatgat atttataaaa
     2401 aagcgttcaa ttataaatat gatacttttt ctgaattaaa aaaagatttt atagaggtat
     2461 taaaataaag gtaggggtgt tatgaattgt ttcttgaaaa tgaataatgt aagtgttcgt
     2521 tatgatgacg taatagcttt aaaagatata actttacaaa taaataaggg agatttcatt
     2581 ggcttattag gttcaaatgg tgcaggtaaa tctacgttaa ttaattctat tgtaggtttt
     2641 caagagattt atttaggaga aatagagtat tgtgataaag atttgatagt tagttctcaa
     2701 ccttttgctc atttaggctt tactcctcaa accacagtaa ttgattttta tactactgtg
     2761 aaggacaatg taatattggg gctgaacctt gctggaaagt ttgggaaaaa tgctgagaag
     2821 ttgtgtcaaa tagccttaga aattgttggg ttagctgata aaaaaaataa tttggtagaa
     2881 acattgtcag gtggacaact gcaacgcgtc cagattgcta gagcaatagc tcataatcca
     2941 gatttttata ttttagatga acctaccgtt ggtttagata ctgaatctgc cgaaaaattt
     3001 ttaatgtatt taaaagataa gagtttggaa ggaaaaacta ttatcatatc ttcacatgac
     3061 ataaatctac tcgaaaagtt ttgtaaaaaa atactttttt tacaaaatgg ctccatatca
     3121 ttttttggtg atatgcgtga ctttgtagat aattcaacta tcaaattaaa tttttcaatg
     3181 cagaatagaa tttctagata tcaaattgaa tttttagaaa attttagatt taaagttcac
     3241 atcgaagata atgatagttt tacaatagaa gtccctatag aagaaaatat cttagatgtt
     3301 atcaatgagg taggaaaagc atgtgaaatt aaaaactttt caacaagtaa attaacctta
     3361 caagaaagtt atttgcaaag aataggagga gaaaaatgaa ggctgatcaa ttaaggcaca
     3421 aatcggactt aggtttaaga ggtctagcga ttattgctaa aaatgagatt attgcttttt
     3481 ttagaagtaa aggtttaatt atttctcagt ttctacaacc aatcttatat gttgttttta
     3541 taataatagg attaaattct tcgataaaga acattcagtt taatgatata aaaacctctt
     3601 atgcagaata tacaatcatt ggtgttatag ctttattgat aatcgggcag atgactcaag
     3661 ttatttatag ggtgacaata gataaaaaat atgggctact tgctcttaag ttatgcagtg
     3721 gagttcgtcc tttatattat attttaggga tgagtatcta ttctatatta gggttgatag
     3781 ttcaagaaat tattatatat ataattacgt tagcgtttga gataaatatc gcaatggata
     3841 gattttttta tacagttttg ttatctattg ttgttttatt attttgggac tcccttgcaa
     3901 ttttacttac aatgtttatc aatgattaca gaagacgtga tattgtaata cgttttgtac
     3961 taacaccgct tggttttaca gctcctgttt tctacttaat agattctgct cctagtattg
     4021 tgagatggat tggtcagtta aatcccttaa cttatcaatt aactattttg agaaactttt
     4081 attttaaaaa ttcaacaact ttggaattag ttttcttatt gttaacatca ttacttgtcc
     4141 ttatatctgt atcttttatt ataccaaaga taaaattgat actgatagaa agataaaagt
     4201 tgggtcatcc aacttttttg ttgtctcccg aaaaccacta gctatgctag tggttccata
     4261 gagcttttag cgtggtaaca aaaagaacct cctaaaatga taagatagaa gtggtttctc
     4321 cgccactaca acatatcata caggaggtac ctcatgagag aggataatca aagtttatca
     4381 cataccacat ggaattgtaa atatcatatt gtttttgcac ccaaatatcg tcgtcaaatc
     4441 atttatggca gatacaaagc tagtatcgga agaatcatac gtgacttatg tgagcgtaag
     4501 ggtgtaataa tccatgaagc gaatgcttgt tcagaccata ttcacatgct tatcagtatt
     4561 cctccgaaac ttagtgtttc gtcctttatg ggctatttaa agggcaagag cagtttgatg
     4621 atttttgata agcatgcgaa tttaaaatac aaatatggca atcgcaagtt ttggtgtaga
     4681 ggctattatg tagatacggt aggccgtaat cagaaagtga tagctgaata tattcagaat
     4741 caattacaag aagacagagt agcagaccag ctcacgttat tcgagtcagt agatccgttt
     4801 actggcgaaa taaataagag gaagtaacta aggtgcttta gcacctgctc gggaaagtgg
     4861 tgcgcgagga agctatttcg gtgggccttt ggccctggcc ggtagaagcg gcttatagcc
     4921 gcagaacaaa ccaccagttc acactggtgg ttttgattta aaaaacttga tacataaaaa
     4981 taaaagtcta tataaaggat ggtaaaattc ctgttgtccg atttggacaa tatcctaaat
     5041 agttacaata tatggtctat actttttctt aggagaaagc tagatgtaca gacgtttgag
     5101 agatttgagg gagggtcatg atctgcccca aaagcaaata gctacaatac tttcgtttac
     5161 aaattcagct tatgccaaaa ttgaacgggg tgagcatgcg ttgacggctg atgtattggt
     5221 taaactctca gatttctatg acgtcagtac agactattta ttgggattaa ctgattttcc
     5281 tgataaaatt cgctttagaa aataatctcc tcaatttcat agagtttgaa aatgagtgag
     5341 attttttatt tgccctttga caactgaata gcctaaaatg gtactttcct catttgtgga
     5401 gcaaatttga atggctcgcc atgataagag cgattttaaa accatcaata aaatagagcg
     5461 atactttata tgccatgata caaatgatat acaatgatac ttctgaccgt tcagcctgcc
     5521 aacgtaaaag agcagcaagt gaaattctta tgatgacttc atcagtcatg ccacgttgaa
     5581 tgtgtgagtt tgttagataa acgcaattaa tcctcaaaag gttccccgaa ccttttgagt
     5641 tctacagacg catcacgtgg agtgtgtaag cttgttgcta aaagcgtaaa aaccttggaa
     5701 cgaaaggaat aatagacttt ctgcgaaaca aaaatataat acaataaaac tatgaatgat
     5761 gaagcaagta aacaattgag cgatagccgt ttcaagatcc ttgtaggtgt tcagcgcacg
     5821 acttttgaag agatgttagc tgtgttaaaa acagcttatc aacgtaaacg cgcaaaaggt
     5881 ggacgaaaaa gcaaattaag cctagacgat ctccttatgg taactattca atacatgcga
     5941 gaatagagca cttatgaaca aattgcggct gattttggca ttcacgaaag caacttaatc
     6001 cgtcggagtc aatgggttga agcaactctt attcaaaatg gttttacgat ttcaaattct
     6061 gccttaattc tgtaaaaaca gtaaaattcg aaggattgta aggtaagagt ttttttcttt
     6121 ctgaaaaaat ggtataatag caatcaaaac tagaaaataa aacggaattt ggaacagatt
     6181 tgtctgtatc ctagtagagt ggtgatacta tgaagattag taagaggcac ttattaaatt
     6241 attccatctt gattccctac ttgcttttat ctattttggg cttgattgtg gtctattcga
     6301 ccaccagtgc tattttaatt gaagaaggca agagcgcctt gcagttggtt cgaaaccaag
     6361 gaatcttttg gattgttagt ttgatactga ttgccttaat ttataaattg agactagatt
     6421 ttttgagaaa tgagcgacta atcattttag ttatattaat agaaatgctt ttattgttct
     6481 tggctcgttt tattggtatt tccgtaaacg gggcatacgg ttggatttcg gttgcaggaa
     6541 taactattca gccagctgag tacttaaaaa tcattattat ttggtattta gctcaccgat
     6601 tctccaaaca gcaagaagaa atagctactt atgattttca agttttgact caaaatcaat
     6661 ggcttccccg tgcttttaat gattggcgat tcgttctcct agttctgatt ggaagtttgg
     6721 gaattttccc tgatttagga aatgcgacta ttttagtctt ggtttccttg attatgtata
     6781 cagttagtgg aatcgcttat cgctggtttt caaccattct ggcgctcgta tctgccgctt
     6841 ctgtctttgt cttgaccact atcagcctaa tcggtgttga gaccttttca aaaattccag
     6901 tattcggcta tgtagccaag cgctttagtg ccttttttaa tccttttgcc gatcgtgctg
     6961 atgcaggtca ccagttagct aattcttatt ttgccatggt caatggcggt tggtttggtc
     7021 taggtcttgg aaactcgatt gaaaaacgag gttatttgcc agaagctcat acagactttg
     7081 tcttttctat cgtgattgaa gaatttggct ttgttggtgc cagtcttatt ttagctctct
     7141 tgtttttcat gattttgcgg attatcttgg tcggtatccg agcggagaat cctttcaatg
     7201 ccatggttgc actcggtgtc ggagggatga tgttggttca ggtatttgtc aatatcggag
     7261 ggatttcggg cttgattcca tctacaggag tgactttccc cttcttatcc cagggtggaa
     7321 atagtcttct agtcttatca gtggcagtag cctttgtctt aaatattgat gccagtgaaa
     7381 aacgcgctaa attgtaccga gaattggaaa atcaaccaat gaaccttctg ttgaagtagg
     7441 ataaagaaag gatagtttat gtctcttcaa aaattagaaa attatagtaa taaaagtgtt
     7501 gtgcaagaag aagtcttgat tctaacagaa ttactggaag atattactaa aaatatgctt
     7561 gccccagaga cctttgaaaa aataatacag ttgaaagaat tatcaacgca ggaagattat
     7621 caaggtctaa accgtctagt gactagctta tcaaatgatg aaatggtcta tatttcacgc
     7681 tatttctcta tcttgcctct tttgattaat atttcagagg atgtggattt agcttatgaa
     7741 atcaatcatc aaaataatat tgatcaggac tatttaggta aattatctac aacgattaaa
     7801 ttggtagcag aaaaggaaaa tgccgttgag atcctagaac acttgaatgt tgtccctgtt
     7861 ttgacagccc atccaacaca agtgcaacgc aaaagtatgt tggatttaac aaatcatatt
     7921 catagtcttt tgcgtaaata ccgtgatgtt aagttggggt tgatcaataa agataaatgg
     7981 tacaatgatt tgcgtcgtta catcgaaatt atcatgcaga cagacatgat tcgtgagaaa
     8041 aaattaaaag tgactaacga aatcacgaat gctatggaat attataacag ctcctttttg
     8101 aaagctgtac ctcatttgac gacggagtat aagcgcttag cgcaagcgca tggtctgaat
     8161 ttaaaacagg ctaaaccaat caccatgggt atgtggatag gtggtgaccg tgatggaaat
     8221 ccatttgtta cagcaaagac cttgaagcag tctgcactca ctcagtgtga agtcatcatg
     8281 aactactatg ataaaaagat ttaccaactt tatcgtgaat tttctctttc aactagcatt
     8341 gtcaacgtca gcaagcaagt cagagaaatg gctcgtcaat ccaaggataa ctcgatttac
     8401 cgcgaaaaag agctttaccg tcgtgccttg tttgatattc aatcaaaaat tcaggcaact
     8461 aaaacctatc tgattgagga tgaagaagtt gggactcgtt atgaaaccgc caatgatttc
     8521 tacaaggatt tgattgccat tcgagattct ctactagaaa ataagggcga gtccttgatt
     8581 tcaggtgatt ttgtggaatt attgcaggca gtagagatat ttggttttta cttagcatca
     8641 attgatatgc gacaagactc tagcgtctat gaagcctgtg tggcagaact cttgaaatca
     8701 gcaggaattc attctcgtta tagcgagttg agcgaagaag aaaagtgtga ccttctcttg
     8761 aaagaattag aagaagatcc ccgaattctt tctgcgactc acgcagaaaa atcagaatta
     8821 ttagcaaaag aattagctat ttttaagacg gctcgtgttt tgaaagataa gttgggagat
     8881 gatgtcatcc gtcagaccat catttcacat gcaaccagcc tttctgatat gctagaatta
     8941 gctattctgt taaaagaagt aggactggtg gatacggaaa gggcgcgtgt tcagattgtt
     9001 cccctttttg aaacaattga agacttggat cattcagagg aaacaatgag aaaatatctt
     9061 tctcttagcc ttgccaaaaa atggattgac tcacgaaata actaccaaga aatcatgctt
     9121 ggctactctg acagtaataa agatggcggt tacttgtcat catgttggac cctctacaag
     9181 gctcaacaac aattgactgc tattggagat gaatttggcg ttaaggttac cttcttccat
     9241 ggtcgtggtg gtactgtcgg tcgtggtggt gggccaacct atgaagccat tacatctcaa
     9301 ccgctcaagt ctatcaagga tcgtatccgc ttgacggagc agggtgaagt aattgggaat
     9361 aaatacggta acaaagacgc cgcttactat aaccttgaaa tgctagtatc ggcagctatt
     9421 aaccgtatga ttactcagaa gaagagcgat accaataccc caaatcgtta tgaaaccatt
     9481 atggatcaag tagtggaccg tagttacgat atctaccgtg atttggtctt tggtaatgag
     9541 catttctatg attatttctt cgagtcaagt ccaatcaagg ctatttcaag ttttaatatt
     9601 ggttctcgtc cagccgctcg taagactatt actgaaatcg gtggtttgcg tgccatccct
     9661 tgggtattct catggtcaca gagtcgtgtt atgttccctg gatggtacgg ggttggttca
     9721 agcttcaagg aatttatcaa taaaaatcca gagaatattg ctatcttacg agatatgtac
     9781 caaaattggc ctttcttcca atcgcttctt tcaaatgttg atatggtttt gtcaaaatca
     9841 aatatgaata ttgcttttga atatgctaaa ctttgtgaag acgagcaagt taaggccatc
     9901 tatgagacta ttttaaatga atggcaagtt actaagaacg ttatcttggc tattgaagga
     9961 catgacgaac tcttagctga caatccatat ctaaaagcta gtctggatta ccgtatgcct
    10021 tactttaata ttctcaacta tattcagttg gagttgatta aacgccaacg tcgtggagaa
    10081 ttgtccagtg atcaagaacg attgattcat atcaccatca acggaattgc gacaggattg
    10141 cgtaattcag gttgataatt ttcaagagtg aatgctaaaa gtgaatatca aaaaaattct
    10201 aatagactat tgacaagtag tttaaaaatg atataattta accattcaga aaagtaatca
    10261 tacaaacttt ttagagagtc tgtggtagct gaaaacagat aagtggcaat gatgaaaatt
    10321 gggctgaatg ctatttagaa tttgaaatta taaaaattcg gtaagcacac cttacagtgc
    10381 atctcgttat tgcgagactg agcgataggg aaattcccta taattgaggt ggtaccgcgc
    10441 atcgacgtcc tcacacaagt tttttgtgtg aggatttttt tgatggaggt tagtatggaa
    10501 agaaaacgat ggcgtcgctt gtttagataa gtgaaatatg ttaaaggaaa taaaaaggag
    10561 aaacagaatg aaaaataaac gtttaattgg aattattgct gcattagcag tcttagtagc
    10621 aggaagcttg atttattctt caatgaataa atcagaagct cagaataata aggatgagaa
    10681 gaaaataacc aagattggtg tgcttcaatt tgtgagccat ccatcccttg atttgattta
    10741 taaagggatc caagatggac ttgcagaaga aggatataaa gatgatcaag ttaaaattga
    10801 ttttatgaac tcagaaggtg atcaaagtaa ggttgcgaca atgagtaaac aattggttgc
    10861 aaatgggaat ggccttgtgg ttggtatcgc aacaccagca gcccaagggt tggctagtgc
    10921 aacaaaagac ctaccagtta tcatggccgc tattacagac ccaattggtg ctaacttggt
    10981 taaagatttg aaaaaaccag gtggcaacgt tacaggggta tctgaccaca atccagctca
    11041 acaacaaatt gaactcatca aggctctgac accgaatgtg aaaacaatcg gagctcttta
    11101 ctcaagtagc gaagacaatt caaaaacaca ggtcgaagaa tttaaggctt atgctgaaaa
    11161 agcaggtctg acagtggaaa catttgcagt tccttcaaca aatgaaattg cctcaactgt
    11221 cactgttatg actagcaagg tagatgctat ttgggttcca attgataaca ccattgcatc
    11281 aggatttcca acggttgtct ctagcaatca aagttctaag aaaccaattt atcccagtgc
    11341 gacagctatg gtagaagtag gtggtttggc atcagttgta attgaccaac atgaccttgg
    11401 tgtggcaaca ggtaaaatga ttgtgcaagt cttgaaaggt gcaaaaccag ccgatacccc
    11461 agtcaatgtc ttttcaactg gtaagtcagt catcaataaa aaaatagcac aagaactagg
    11521 tattactatt cctgagtctg ttctcaaaga agcaggacaa gtcatcgaat aaataaggta
    11581 gggaggagga gactcttccc attttttaaa aagatgaata tagaaaggat taaataaaat
    11641 atgattgttt ccattatttc tcaaggattt gtctgggcta ttctaggtct gggaatcttt
    11701 atgacattta ggattttaaa ctttccagat atgacgacag aaggttcctt ccctcttggg
    11761 ggagctgttg ctgtcacttt gataaccaaa ggcgtgaacc catttttagc gacacttgtt
    11821 gctgtaggag caggttgttt ggctggaatg gcagcaggcc ttctttatac aaaagggaag
    11881 atcccaacct tgctctcagg gattttggtg atgacttctt gtcactcaat catgctcttg
    11941 attatgggac gtgcgaattt aggcctgctt ggaaccaagc aaattcagga tgttttgcct
    12001 tttgattcgg atttgaatca actcttgaca ggtctcatct ttgtgagtat tgttattgct
    12061 ctcatgctct ttttcttgga cactaaactc ggacaagcct atattgctac aggagataat
    12121 cctgatatgg ctagaagttt cgggattcat actggacgca tggagctcat gggcttggtc
    12181 ttatcaaatg gtgtgattgc ccttgcaggt gccctcattg ctcagcaaga aggctatgcc
    12241 gatgtgtctc gagggatcgg ggttatcgtt gtggggcttg caagtttgat tattggagaa
    12301 gttattttca agagtttgag cttggcagag cgtttggtta ctatcgttgt aggttctatc
    12361 gcttatcaat ttttagtgtg ggcagttatc gcacttggct ttaatacaag ttaccttcgt
    12421 ttatacagtg ccttgatttt agcagtctgc ctcatgattc caacatttaa gcaaacaatc
    12481 ttgaaaggag ccaagttaag caaatgacag caattgtaga attaaaaaat gcaaccaaaa
    12541 tcgttaaaaa tggctttgat gaagaaaaga ttattttaaa tgatgtttcc ttagaaattt
    12601 ttgaacagga ctttatcacg attttgggtg gaaatggtgc tggtaaatca accctcttta
    12661 acactatagc agggacctta tcactaacta gtggaactat ccgtatttta ggtgaagatc
    12721 tcactaagtt ttcacccgag aagcgtgcca agtacctgtc tcgtgtcttc caagatccaa
    12781 agatggggac agctccccgt atgacggtcg ctgaaaatct tttaatcgcc aagtttcgtg
    12841 gtgaaaagcg tggattgtta ccacgacgct tgactagcta taaggatgaa tttcaggcaa
    12901 ccattgaaaa agtaggaaat ggtcttgaga aacacttgaa tacaccgatt gagttcttat
    12961 caggtggaca aagacaggct ttgagtctct tgatggcaac cttgaagcga cctgaattac
    13021 tcctgttaga tgagcatact gctgccctgg atccaaagac tagtgttgct ttgatggaat
    13081 tgacagatga atttgttaag aaagatcagc taacagccct tatgattact catcatatgg
    13141 aagatgctct caaatacggc aatcgcttga ttgtcatgaa agaaggacgg attatccaag
    13201 atttaaacca agaagaaaaa gcaaaaatga aaatctctga ttattatcaa ctctttgaat
    13261 aaagtaggga aaatgagtga aatggtttac tttttttctg aaataaagta tactatataa
    13321 agtaaactat gataacatgg aggtattgtg tatggttgac aaacaagtca ttgaagaaat
    13381 caaaaacaat gccaacattg tggaagtcat aggagatgtg atttctttac aaaaggcagg
    13441 acggaactat ctagggctct gtccttttca tggcgaaaaa acaccatctt tcaacgttgt
    13501 agaggataag cagttttatc actgtttcgg ttgtggtcgc tcaggtgatg tctttaagtt
    13561 catcgaggag taccaagggg ttccctttat agaggcagtc caaatcttag gtcagcgtgt
    13621 tggaattgag gttgaaaaac cgctttatag tgagcagaag ccagcctcac ctcaccaagc
    13681 tctttatgat atgcacgaag atgcagccaa attttaccat gctattctca tgacaacgac
    13741 tatgggcgaa gaggccagaa attaccttta tcagcggggt ttgacagatg aagtgcttaa
    13801 acatttttgg attggtttag cacctccaga acgaaactat ctctatcaac gtttgtctga
    13861 tcagtatcgt gaagaggatt tactggattc aggcctgttt tatctctcgg atgccaatca
    13921 atttgtagac acctttcaca atcgcattat gtttcccctg acaaatgacc aaggaaaagt
    13981 cattgccttc tcaggtcgta tctggcaaaa aacagattca caaacttcta agtataaaaa
    14041 cagccgatcg actgcaattt ttaacaaaag ttacgaatta tatcatatgg atagggcaaa
    14101 aaaatcttct ggaaaaacta gtgagattta cctgatggaa ggattcatgg atgttattgc
    14161 agcctatcgg gctggaatcg aaaatgctgt ggcgtcgatg ggaacggcct tgagtcgaga
    14221 gcatgttgag catctgaaaa ggttaaccaa gaaattggtt cttgtttacg atggagataa
    14281 ggctgggcaa gccgcgatat tgaaagcatt ggatgaaatt ggtgatatgc ctgtgcaaat
    14341 cgttagcatg cctgctaact tggatcctga tgagtatcta caaaaaaatg gtccagaaga
    14401 cttggcctat ctattaacga aaactcgtat tagtccgatt gagttctaca ttcatcagta
    14461 caaacctgaa aacagtgaaa atctgcaggc tcagattgag tttattgaaa aaatagctcc
    14521 cttgattgtt caagaaaagt ccatcgctgc tcaaaacagc tatattcata ttttagctga
    14581 cagtctggcg tcctttgatt atgcccagat tgagcagatt gttaatgaga gtcgtcaggt
    14641 gcaaaggcag aatcgcatgg aaggaatttc cagaccgacg ccaatcacca tgccaatcac
    14701 caagcagtta tcggctatta tgagggcaga agcccatcta ctctatcgga tgatggaatc
    14761 ccctcttgtt ttgaacgatt accgtttgcg agaagacttt gcatttgcta cacctgaatt
    14821 tcaggtctta tatgacttgc ttggccagta tggaaatctt cctccagaag ttttagcaga
    14881 gcagacagag gaagttgaaa gagcttggta ccaagtttta gctcaggatt tgcctgctga
    14941 gatatcgccg caggaactta gtgaagtaga gatgactcga aacaaggctc tcttgaatca
    15001 ggacaatatg agaatcaaaa agaaggtgca ggaagctagc catgtaggag atacagatac
    15061 agccctagaa gaattggaac gtttaatttc ccaaaagaga agaatggagt aataatggca
    15121 acaaaacaaa aagaagtaac aacatttgac gtacaggtag cagaatttat ccgtaatcat
    15181 aagcaaaaag ggacagcgac agatgatgaa atcaatgcaa gtctggttat tccttttacc
    15241 ttggacgctg atgggattga agatctcttg caacggattc aggatgcagg catttctatc
    15301 acagataacg aaggaaatcc aagtgcgcgt gttcttagca atgaagaaga accagaactc
    15361 agcgatgagg acttgattgg gtcaacttct gctaaggtca atgaccctgt ccgtatgtac
    15421 ttgaaagaaa taggggtcgt tcctctcttg accaatgaag aggagaaaga gttggcactg
    15481 gctgttgaag ctggcgatat cgaagccaaa caacgtcttg cggaagccaa tcttcgtttg
    15541 gttgtttcca ttgccaaacg ctatgtcggt cgtggcatgc agttccttga cttgattcaa
    15601 gaaggaaata tgggcttgat gaaggcggtt gacaagtttg actattctaa agggttcaag
    15661 ttttcaactt atgcaacttg gtggattcgt caggctatca ctcgtgctat tgcggatcaa
    15721 gctcgtacca tccgtatccc agttcacatg gttgaaacta tcaataaatt ggttcgtgaa
    15781 cagcggaatc tccttcaaga attggggcaa gatccgacac cagaacagat tgctgaacga
    15841 atggatatga cacctgataa ggttcgtgaa atcttgaaga ttgcccaaga accagtatct
    15901 cttgaaactc ctatcggtga agaggacgat agccaccttg gagactttat cgaagatgaa
    15961 gtgattgaaa atccagtgga ttatacgact cgtatcgtct tgcgtgagca attggatgaa
    16021 atcttagata ctcttacaga ccgtgaagaa aatgttctgc gtctacgttt tggactagat
    16081 gatggaaaaa tgcgcacact tgaagatgtg gggaaagtct ttaacgtaac tcgtgagcgt
    16141 atccgtcaga ttgaagcaaa ggctttgaga aaactacgcc aaccaagccg cagcaaaccg
    16201 cttcgtgatt ttattgaaga ctaagagtga ggaaaatatg gcttatacag aagagcaaat
    16261 tgaaaacatc aaaacacgga ttttaacagc cttggaagaa gtcatcgacc ctgagttggg
    16321 aatcgatatt gtcaatcttg gtttgatcta tgagattcgt tttgacggtg acacagggca
    16381 aacagagatt gacatgactt tgacaactat gggttgtccc ttagcagacc ttttgacaga
    16441 ccagatttat gatgctatga tagaggttcc agaagtaacg gatactgagg ttaaattagt
    16501 ctggtatcca gcctggacag ttgaaaaaat gagtcgctat gcccgcattg ccctaggcat
    16561 taagtaaaca tataaaagca tgtgagagac tagaggaaaa gcgaggaaat ttcccctctt
    16621 ttcctctagt ctctcctttc ttttgctgat tttattcaaa gaaaatgata taatagtagt
    16681 tatggagaaa aagaaattac gcatcaatat gttgagttca agtgagaaag tagcaggaca
    16741 gggagtttca ggtgcttacc gtgaattagt tcgtcttctt caccgtgctg ccaaggacca
    16801 attgattgtt acagaaaatc ttccaatcga ggcagatgtg actcactttc atacgattga
    16861 ttttccctat tatttatcaa ccttccaaaa gaaacgctca gggagaaaga ttggctatgt
    16921 gcatttcttg ccagctacac ttgagggaag tttgaaaatt ccatttttct taaagggaat
    16981 tgtgaaacgc tatgtatttt ctttttacaa ccggatggag cacttggttg tggtcaatcc
    17041 tatgtttatt gaggatttgg tagcagctgg tattccacgt gaaaaagtga cctatattcc
    17101 taactttgtc aacaaggaaa aatggcatcc tctaccacaa gaagaggtag ttagactgcg
    17161 cacagatctt ggtcttagtg acaatcagtt tatcgtagta ggtgctgggc aagttcagaa
    17221 acgtaaaggg attgatgact ttatccgtct ggctgaggaa ttgcctcaga ttacctttat
    17281 ctgggctggt ggcttctctt ttggtggtat gacagatggt tatgaacact ataagaaaat
    17341 tatggaaaat ccccctaaaa atttgatttt tccaggcatt gtatcgccag agcggatgcg
    17401 cgaattgtat gctctagcgg atcttttctt gttgcctagt tacaatgagc tctttcctat
    17461 gactatttta gaagctgcga gttgtgaggc tcctattatg ttgcgtgatt tagatctcta
    17521 taaggtgatt ttggagggaa attatcgggc gacagcgggt agagaagaga tgaaagaggc
    17581 tattttggaa tatcaagcaa atcctgctgc cttaaaagat ctcaaagaaa aggctaagaa
    17641 tatttccaga gagtattctg aagagcatct gttacaaatc tggttggact tttatgagaa
    17701 acaagccgct ttagggagaa agtaaaaagt gaggtaatct atgcgaattg gtttatttac
    17761 agatacctat tttcctcagg tttctggtgt tgcgaccagt attcgaacct tgaaaacaga
    17821 acttgaaaag cagggacatg ctgtttttat ctttacgacg acagataagg atgtcaatcg
    17881 ctacgaagat tggcaaatta tccgcattcc aagtgttcct ttctttgctt ttaaggatcg
    17941 tcgctttgcc taccgaggtt ttagcaaggc acttgaaatt gctaaacagt atcagctaga
    18001 tattatccat actcagacag aattttctct tggcctgttg gggatttgga ttgcgcgtga
    18061 attgaaaatt ccagtcatcc atacctatca cacccagtat gaagactatg tccattatat
    18121 tgctaagggg atgttgatcc ggccgagtat ggtcaagtat ctggttagag gtttcctgca
    18181 tgatgtggat ggggttattt gccctagtga gattgtccgt gacttgctat ctgattataa
    18241 ggtcaaggtt gaaaaacggg tcattcctac tgggattgaa ttagccaagt ttgagcgtcc
    18301 ggaaatcaag caggaaaatt tgaaagaact gcgtagtaaa ctagggattc aagatggtga
    18361 aaagacgttg cttagtcttt cgagaatctc ctatgaaaaa aatattcaag cagttttagt
    18421 agcctttgct gatgttctga aagaggaaga taaggttaaa ctggtagtag ctggggatgg
    18481 cccttatctg aatgacctca aagagcaagc ccagaaccta gagattcaag actcagtcat
    18541 ctttacaggg atgattgctc ctagtgagac ggctctttac tataaagcgg cggatttctt
    18601 catttcggca tcgacaagcg aaacgcaagg tttgacctac ttggaaagct tagccagtgg
    18661 aacacctgtc attgctcacg gaaatcctta tttgaacaac ctcatcagtg ataaaatgtt
    18721 tggaaccttg tactatggag aacatgattt ggctggtgct attttggaag ccctgattgc
    18781 aacaccagac atgaacgagc ataccttatc agagaaattg tatgagattt cagctgagaa
    18841 ctttgggaaa cgagtgcatg agttttatct ggatgccatt atttcaaata acttccagaa
    18901 agatttggct aaagatgata cggtcagtca gcgtatcttt aagacagttt tgtatcttcc
    18961 gcaacaggtg gttgctgtac ctgtaaaagg atctagacgc atgttgaagg cttcaaaaac
    19021 acagttgatc agtatgagag actattggaa agaccatgaa gaatagaaag aggaacagct
    19081 atgaaaaaaa caattaatga gaagcggtcg tgataaaaag attgcgggtg tttgtgctgg
    19141 ggtggcccat tatctggata tggatccgac tatcgttcaa gtcatttggg gtgttcttac
    19201 ttgctgttac ggagctggaa ttgtagctta cattatttta tggattatcg caccagtagc
    19261 aactgactat tgaaaactag ctcaattcat gctaagataa tagaaaatag aatgtaacga
    19321 aggagagaaa aatggcattt ggagataatg gaaatcgtaa aaaaactatg tttgagaaaa
    19381 taaccttgtt tatcgtgatt atcatgctag tagcaagttt attgggaatt tttgcaactg
    19441 caattggtgc cctcagtaat ctataaaata gattcaagaa aatttagtga ctgggatttc
    19501 ccagcccttt tttaaagtga gaagaaataa tgagtatgtt tttagataca gctaagatta
    19561 aggtcaaggc tggtaatggt ggcgatggta tggttgcctt tcgtcgtgaa aaatatgtcc
    19621 ctaatggagg cccttggggt ggtgatggtg gtcgtggagg caatgtggtc ttcgttgtag
    19681 acgaaggact acgtaccttg atggatttcc gctacaatcg tcatttcaag gctgattctg
    19741 gtgaaaaagg gatgaccaaa gggatgcatg gtcgtggtgc tgaggacctt agagttcgag
    19801 taccacaagg tacgactgtt cgtgatgcgg agactggcaa ggttttaaca gatttgattg
    19861 aacatgggca agaatttatc gttgcccacg gtggtcgtgg tggacgtgga aatattcgtt
    19921 tcgcgacacc aaaaaatcct gcaccggaaa tctctgaaaa tggagaacca ggtcaggaac
    19981 gtgagttaca attggaacta aaaatcttgg cagatgtcgg tttagtagga ttcccatctg
    20041 tagggaagtc aacactttta agtgttatta cctcagctaa gcctaaaatt ggtgcctacc
    20101 actttaccac tattgtacca aatttaggta tggttcgcac ccaatcaggt gaatcctttg
    20161 cagtagccga cttgccaggt ttgattgaag gggctagtca aggtgttggt ttgggaactc
    20221 agtttctccg tcacatcgag cgtacacgtg ttatccttca catcattgat atgtcagcta
    20281 gcgaaggccg tgatccatat gaggattacc tagctatcaa taaagagctg gagtcttaca
    20341 atcttcgcct catggagcgt ccacagatta ttgtagctaa taagatggat atgcctgaga
    20401 gtcaggaaaa tcttgaagaa tttaagaaaa aattgtctga aaattatgat gaatttgaag
    20461 agttaccagc tatcttccca atttctggat tgaccaagca aggtctggca acacttttag
    20521 atgctacagc tgaattgtta gacaagacac cagaattttt gctctacgac gagtccgata
    20581 tggaagaaga agcttactat ggatttgacg aagaagaaaa agcctttgaa attagtcgtg
    20641 atgacgatgc gacatgggta ctttctggtg aaaaactcat gaaactcttt aatatgacca
    20701 actttgatcg tgatgaatct gtcatgaaat ttgcccgtca gcttcgtggt atgggggttg
    20761 atgaagccct tcgtgcgcgt ggagctaaag atggggattt ggtccgcatt ggtaaatttg
    20821 agtttgaatt tgtagactag gagactggta tgggagataa accgatatct ttccgagatg
    20881 cggatggtaa ttttgtttcc gccgcagacg tttggaatga aaagaaattg gaagaactat
    20941 ttaatcgtct caatccaaat cgtgccttga gattggcacg aactaaaaag gaaaatccat
    21001 ctcagtaaag aagctaaaaa atcccggctc tttgtcaact gtagtgggtt gaaaaaaagc
    21061 taagctcgag a
//
LOCUS       DAVEHY010000042        19129 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVEHY010000042 DAVEHY010000000
VERSION     DAVEHY010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19129
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.042"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            66..622
                     /locus_tag="VUZ44_001807"
                     /pseudo
     CDS             66..622
                     /locus_tag="VUZ44_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
     gene            843..1949
                     /locus_tag="VUZ44_001808"
     CDS             843..1949
                     /locus_tag="VUZ44_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU0320675.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            1925..3316
                     /locus_tag="VUZ44_001809"
     CDS             1925..3316
                     /locus_tag="VUZ44_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320676.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            3313..4491
                     /locus_tag="VUZ44_001810"
     CDS             3313..4491
                     /locus_tag="VUZ44_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU0320677.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            4916..5149
                     /locus_tag="VUZ44_001811"
     CDS             4916..5149
                     /locus_tag="VUZ44_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU0320678.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            5432..7381
                     /gene="mutL"
                     /locus_tag="VUZ44_001812"
     CDS             5432..7381
                     /gene="mutL"
                     /locus_tag="VUZ44_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU0320679.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(7706..8173)
                     /locus_tag="VUZ44_001813"
     CDS             complement(7706..8173)
                     /locus_tag="VUZ44_001813"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU0320680.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEISLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(8174..9379)
                     /locus_tag="VUZ44_001814"
     CDS             complement(8174..9379)
                     /locus_tag="VUZ44_001814"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU0320681.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRIHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(9399..10034)
                     /gene="ribE"
                     /locus_tag="VUZ44_001815"
     CDS             complement(9399..10034)
                     /gene="ribE"
                     /locus_tag="VUZ44_001815"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU0320682.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(10019..11119)
                     /gene="ribD"
                     /locus_tag="VUZ44_001816"
     CDS             complement(10019..11119)
                     /gene="ribD"
                     /locus_tag="VUZ44_001816"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU0320683.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(11253..11367)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            11524..12117
                     /gene="ruvA"
                     /locus_tag="VUZ44_001817"
     CDS             11524..12117
                     /gene="ruvA"
                     /locus_tag="VUZ44_001817"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU0320684.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            12127..12690
                     /locus_tag="VUZ44_001818"
     CDS             12127..12690
                     /locus_tag="VUZ44_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU0320685.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            12687..13364
                     /locus_tag="VUZ44_001819"
     CDS             12687..13364
                     /locus_tag="VUZ44_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU0320686.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(13519..14550)
                     /locus_tag="VUZ44_001820"
     CDS             complement(13519..14550)
                     /locus_tag="VUZ44_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU0320687.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCPKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(14805..15488)
                     /locus_tag="VUZ44_001821"
     CDS             complement(14805..15488)
                     /locus_tag="VUZ44_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU0320688.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(15500..16444)
                     /locus_tag="VUZ44_001822"
     CDS             complement(15500..16444)
                     /locus_tag="VUZ44_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU0320689.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            complement(16606..17772)
                     /locus_tag="VUZ44_001823"
     CDS             complement(16606..17772)
                     /locus_tag="VUZ44_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU0320690.1"
                     /translation="MKITEVIKKDGSKVYRANVYLGVDQVTGKKVKTKVTGRTQKELK
                     QKANQEKIAFQKAGSTRQKASTIKNYQELANLWLESYKNTVKPNTQGNVRKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKGAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRQKVKHFENQELKKFLGYLDNLDTHRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHVTKTLNRDIEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRESVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            complement(18005..18970)
                     /locus_tag="VUZ44_001824"
     CDS             complement(18005..18970)
                     /locus_tag="VUZ44_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEU0320691.1"
                     /translation="MQKPFKTIPEQIELLHKRGLIITDYKRAKKYLLTNNYYSIINGY
                     SKYFEQSPNKYRPGTNFSEITYSYFYDKEIKYSFLKAILEAEKHIKSAIAYVFSERFA
                     STPYFYLDINNYNKSNSDNVRKIKFVIRQMVKIIDKHKSSRQANSIQHYFSKHLEIPF
                     WVIIDYLTFGDMLAILQTLPISLQDKISKKFYSFICEHIKININFTPAILVSFVENIG
                     EVRNVCAHDNRLFSFKCKKSVKYYSDLHSNYGISNSCAKSSPYHVFIVLQCFLSSIEY
                     AKLHNTLLSRFKTFEKHLLTVSIDKFLTELGFPANWHRTMPKLPQ"
BASE COUNT         5792 a         3247 c         3618 g         6472 t
ORIGIN      
        1 ggtcctgcga attttattta gaaatcaatt tctactaatt gagtattaat gggtaaaaag
       61 attgtatgga taagaaaaat ttacttgtat tggttactgg ttcggtaggt gccagtaatg
      121 tagatacata cttatattat ataaaaaaat tctataatgt taaagtgata ctttctgaaa
      181 attctaaaaa atttataagt aaggaattaa ttagttattt ttgtgataaa gtttatgatg
      241 aaatatttgt tgaagaggta gttccgcacg tttttctgcc atatgaatct gacttacttc
      301 ttattttacc agctacggca aatgtgattg gcaaaattgc taatggtatt gctgatgatt
      361 tagttacagc aactgtttta aactttaata aaaaaataat tttttgtccc aatatgaact
      421 ctactatgtg ggacaatcac atagttcaaa gaaatgtatc aattctaaag gagttgggac
      481 atatattttt atttgagtct aaaaaacata tgaggtagga ttgcgtaaag caatagattc
      541 aacatgttca atgttacaac cacagtcgtt agtaaaagaa cttatcaaat tagaaaatat
      601 tgtccttgaa gagggacatt aaaaactact gagaatatta atgaggggaa aaaatggaaa
      661 attcatcaat cgatgtagat atgctgttgg aagaattgac acaagaagca atggtcgttg
      721 ttgctgttga taaggactgt taatttaaac ttatggcaat atatgaaagg ttactggatg
      781 ttttaaatta tgcaggcagt agccttttat tatatacaaa tggataaagt aaggataata
      841 caatgattaa taaaaaaata caacaagttg ttttggaatc attacagaat tttttgaatg
      901 ggaacttcat ttcgccttgt gtagtctatg attttggctt gctggaaact gtacttgatg
      961 aatttaaaaa tcaaattcct gtaacattca attaccaact tttttatgcc gttaaagcaa
     1021 attcaaatga gaagatactt gaattcttag tagataaaat tgatggagtt gatgtggcgt
     1081 cattatctga attagatgtg gctaaaaaat ttttcccacc aactcaaatt tctgttaatg
     1141 gtcccgcatt ttcttatgaa actttatata atctgattaa aaaacaatat aaagttgata
     1201 ttaacttttt ggaacatctt caacaatttt ccccaaaaga atctgttgga ataagagtaa
     1261 cggagccaga tgaacttaat aatcgtatga gtcgatttgg aataaatatt tgcagtgata
     1321 attggactag taatttacaa aatcctttaa ttacacgact gcattttcat tttggagaaa
     1381 aagatgataa atttattgtt aagttagata aaatattatt taagttacaa gaaattaata
     1441 aacttagaga ggttagagaa ataaatcttg gaggcggttt tatgaaatta tttatggaaa
     1501 atcgtttgaa agaatttttt ctatcactta tggaaatcta taaaaagtac gatattgata
     1561 gtactgtgac tacaataata gaaccaggta gtgcaattac ttcattttct gcctatatga
     1621 ttactagccc agttaatgtt agtgaggtga atgagcagca ggttatcacg ttagacacat
     1681 caatatacac caatacatta tggtttgttc cgcatattat tacaacgtta aattcaagta
     1741 gtaaagagcg ttatagtact attctctatg gtaatacctg ttatgaacat gacaagtata
     1801 aaatgaaagt ttcgcttcca aggttaactc aaaatagcag tatagtgttt tttcctgtag
     1861 gagcttatat aaaaagcaat cattcaaatt tacatcgtaa tgattttatg cgggaggtat
     1921 atttgtggac aaaaaacttg acatattaga taaagttaag gaatatttag gaaataaaac
     1981 tactcaaatt ctggataatc aatataaaga atttttgaaa cttaatgata taaggcgagc
     2041 gtttggtatt tcagaaaaag tattaaacaa ttcttttaat tttacgagta aagaatttaa
     2101 tgatttaatt aataacgaaa attatttatt cgaatatgca tgtagaatta gagaggaatg
     2161 gagaaaaaaa tgctttaatc attcttatcg ttttctatgc tcacctataa ttacagatga
     2221 ttttcttaac acgaagacat tgagaagtag ccaaattgaa tataaatatg agcgatattt
     2281 atcgaaaagt tcgataggcg atagagcggt tgatggcttt gtttccttca atactttaac
     2341 agctaatggt atgtctgcta ttaaactatg tcttgagata ttaaactcta ttttcttcaa
     2401 gaagaagatt gatttattat attcaaccgg atattatgaa acaagatttt tattaaataa
     2461 tcttgctaaa tcaggtatta gttgctatga ggtaagtaat tgtgaattgg ataaagataa
     2521 attttataat gtattcatga tggaacccaa tcgagccgat ttaacattac aaaaaactga
     2581 tttcaagata gtagaatatt ttgttaagta taaaaataat tcaataaaag tcgttatttt
     2641 agatatttca tatcaaggtt ctaattttaa attagtagaa tttttagaga aatttaaatt
     2701 tgcgaatgta attatttttg tggtacgatc tttgataaaa ttagatcaaa tgggattaga
     2761 attgacaaat gggggaataa tagaagtgtt tattcctaat catttgagaa agttgaaaaa
     2821 ttttattgaa gaggaattca ataaatttag aaattctcac ggagctaatc taagcctcta
     2881 tgaatactgt ttgcttgata attctttaac tttaaaaaat gattggaact attctgattt
     2941 agttatgaaa tttacgagta atttttatgc tgatataaaa gacttgttca tggaaaattc
     3001 tgatattgaa atcatccatg aagagggagt accttttgta tttttagatt taataggtga
     3061 aggtaaaaaa gaatatgaaa tgttttttca atggttaaac ttcttttaca aacagcttgg
     3121 aatcacattg tatgctagaa atagttttgg gtttcggaat ctaacagtag agtattttgg
     3181 aattattggg acagaaagat atatatttaa gatttgtcca ggtgtttata aagggttaag
     3241 ttattatttg atgaaatttt tattaaaatc tttttcaaat gaatatttaa aaactactga
     3301 tgaggttaat agatgaaaaa tttgataaag ttgctaataa ttagattgat tgttaactta
     3361 gcagacagtg tattttatat agtagcattg tggcacgtta gcaataatta ttcttcgagc
     3421 atgttcttag gaatatttat tgcagtaaat tatctaccgg atttgttact aatctttttt
     3481 ggaccagtta ttgacagagt aaatccgcaa aaaattctta taatatcaat tttggttcaa
     3541 ttagcagtgg ctgtaatatt tttattatta ttaaaccaaa tatcattttg ggtgataatg
     3601 agtctagtgt ttatttcagt aatggctagc tccataagtt acgtgataga agatgtgttg
     3661 attcctcaag tggtagaata tgataagatt gtatttgcaa attctctttt tagtatttcg
     3721 tataaagtat tagattctat ttttaattca ttcgcatcat ttttacaggt ggcagtagga
     3781 tttattttat tggttaagat agatataggc atatttttac ttgctctatt tatattgttg
     3841 ttgttaaaat ttagaactag caatgcgaat atagaaaact tctctttcaa atattacaag
     3901 agagaagtgt tgcaaggtac aaagtttatt ttaaataata aattattatt taaaaccagt
     3961 atttctttaa cgcttataaa ctttttttat tcatttcaga cagtagttgt accgattttt
     4021 tctattcgat attttgatgg tccgattttt tatggtattt ttttaactat tgctggtttg
     4081 ggtggtatat tgggaaatat gctagcgcca atcgtaataa aatatttaaa atcgaatcaa
     4141 attgttggtg tatttctttt tttgaacggc tcaagttggt tagtagcaat tgttataaaa
     4201 gactatactt tatcacttat tttatttttc gtttgtttta tgtctaaagg agtcttcaat
     4261 attattttta attcgttgta ccaacaaata cctccacatc aacttcttgg tagggtaaat
     4321 actaccattg attctattat ttcttttgga atgccaattg gtagtttagt tgcaggaacg
     4381 cttattgatt tgaatattga attagtgtta attgctatta gcatacctta ttttttgttt
     4441 tcttatattt tttatacgga taatggattg aaagaattta gtatatatta gaaatgttta
     4501 tgttcattca aaagcataat gactataact gaaaaagaaa agtgatatct ttaaggttgt
     4561 tcttcttggt ggtgagattc gtgagacaac ccaagctttt gtcggaaaga ttaccaatgc
     4621 tttgatggat aggatgtact ttagcaagat gtttttagtg gtaacggtat cgtggatgga
     4681 cgtgtaataa cctcttcttt cgaggagtat tttactaaaa aactagcctt ggagcgttcc
     4741 ccagaaacgg acttactcat tgactcttca aagatttggg gagaagattt tgcttcatct
     4801 gttccttgaa aaaagtcaca gcagtcatca cagacgatag tactgaacaa aactatgaag
     4861 agttagaaat ttatacgcag gtgattgtat aaaggatctg gaaatagata agaagttgat
     4921 tagtattgac ctaggtggta caaatattaa gattactgtt ctttcaaatg acggtgagat
     4981 tgaaactttg tggagtatta caacagatac aagtgagaaa ggttctcaaa ttatatcgga
     5041 catcatcagt tctattaaaa ataaattgac cgaacggaat attcctgata gcgaccttct
     5101 tggaatcggt atgggaagtt gctcatcata ctttccttgt aaatcatagg ggctataaac
     5161 tctccgtcta cttgtcctgc aacaattgaa gtctgctcaa aacgccgtcc gctaatcttt
     5221 tcatagactt tctccctttt aggagcctag ctttctagtt tgttctttga tttttattga
     5281 gtataccact attttactcc ctctggcaag ggactttgtc tatgtggagg gattgggctc
     5341 ctatgtggtg gagcttttct gttctttctg aaatatggta taatagcact aatcaatttc
     5401 taggaaaata gatacagaaa ggggctgaaa gatgtctcat attattgaat tgccagagat
     5461 gctggcaaac caaatcgcgg ctggagaggt cattgaacgt cctgccagtg tggtcaaaga
     5521 gttggtagaa aatgccattg acgcgggctc tagtcagatt atcattgaga ttgaggaagc
     5581 tggtctcaag aaggttcaaa tcacggataa cggtcatgga attgcccacg atgaggtgga
     5641 gttggccctg cgtcgccatg cgaccagtaa gataaaaaat caagcagatc tctttcggat
     5701 tcggacgctt ggttttcgtg gtgaagcctt gccttctatt gcgtctgtta gtgtcttgac
     5761 tctgttaacg gcggtggatg gtgctagtca tggaaccaag ttagtcgcgc gtgggggtga
     5821 agttgaggaa gtcatcccag cgactagtcc tgtgggaacc aaggtttgtg tggaggatct
     5881 ctttttcaac acgcctgccc gtctcaagta tatgaagagc cagcaagcgg agttgtctca
     5941 tatcattgat attgtcaacc gtctgggctt ggcccatcct gagatttctt ttagcttgat
     6001 tagtgatggc aaggaaatga cgcggacagc agggactggt caattgcgcc aagcaatcgc
     6061 agggatttac ggtttggtca gtgccaagaa gatgattgaa attgagaact ctgacctaga
     6121 tttcgaaatt tcaggttttg tgtccttgcc tgagttgact cgggctaacc gcaattatat
     6181 cagcctcttc atcaatggcc gttatattaa gaacttcctg ctcaatcgtg ctattttgga
     6241 tggttttgga agcaagctta tggttggacg ttttccactg gctgtcattc acatccatat
     6301 cgacccttat ctagcggatg tcaatgtgca tccaactaag caagaggtgc ggatttccaa
     6361 ggaaaaagaa ctgatgactc tggtttcaga agctattgca aatagtctca aggaacaaac
     6421 cttgattcca gatgccttgg aaaatcttgc caaatcgacc gtgcgcaatc gtgagaaggt
     6481 ggagcaaact attctcccac tcaaagaaaa tacgctctac tatgagaaaa ctgagccgtc
     6541 aagacctagt caaactgaag tagctgatta tcaggtagaa ttgactgatg aagggcagga
     6601 tttgaccctg tttgccaagg aaaccttgga ccgattgacc aagccagcaa aactgcattt
     6661 tgcagagaga aagcctgcta actacgacca gctagaccat ccagagttag atcttgctag
     6721 catcgataag gcttatgaca aactggagcg agaagaagca tccagcttcc cagagttgga
     6781 gtttttcgga caaatgcacg ggacttatct ctttgcccaa gggcgagatg gactttacat
     6841 catagatcag cacgctgctc aggaacgggt caagtacgag gagtaccgtg aaagcattgg
     6901 caatgttgac cagagccagc agcaactcct agtgccctat atctttgaat ttcctgcgga
     6961 tgatgccctg cgtctcaagg aaagaatgcc tctcttagag gaagtgggcg tctttctagc
     7021 agagtacgga gaaaatcaat ttattctacg tgaacatcct atttggatgg cagaagaaga
     7081 gattgaatca ggcatctatg agatgtgcga catgctcctt ttgaccaagg aagtttctat
     7141 caagaaatac cgagcagagc tggctatcat gatgtcttgc aagcgatcta tcaaggccaa
     7201 tcatcgtatt gatgatcatt cagctagaca actcctctat cagctttctc aatgtgacaa
     7261 tccctataac tgtcctcacg gacgtcctgt tttggtgcat tttaccaagt cggatatgga
     7321 aaagatgttc cgacgtattc aggaaaatca caccagtctc cgtgagttgg ggaaatatta
     7381 aaagtataaa aaagtctggg aaaaattttc aaaatcagaa aaacgcataa aatcaggtgt
     7441 tcaaaaacct tgattttatg cgttttatca tagaaatatt tacttcattt tttcctaatt
     7501 cttttcgaaa ctctttttaa acgacgtcag ttttatcagt aatctcaaaa cagtgttttg
     7561 agctaatttt gccagttttg tctgtaacat cgaagttgtg tttgaccact ctgcgactgg
     7621 tttcctagtt tgctctatga ttttcacaga gtattaaatt gcgattttgc caagtttctt
     7681 tattcgtcta aaagtagagt ctgttctatg cgtctaatgt acgaattagg ttgaccattt
     7741 caatagctcc ttgtgcacac tcagaaccct tatttcctgc tttagtacca gctcgttcta
     7801 tggcttgttc aattgtatct gtcgttagca caccaaacat aacaggaatt tcgctattta
     7861 aactgatttg ggcgattccc ttagatacct cgctacatac ataatcataa tgacttgtat
     7921 tccctctaat gacagctccc aagcagataa ttgcatcata ttttttactt tttgccattt
     7981 ttgatgcaat cagtgatatt tcaaaagctc ctggaaccca ggctacctct atatctttct
     8041 cgtttacatt ctctcttttg agattatcta gtgctccaga taataatttt gaagttataa
     8101 attcattaaa tctcgctaca acaataccta ttttaatatt gtttgctact aaattacctt
     8161 cataagtgtt catttatttt tcctccatat ttaaaatgtg acccattcga tttttctttg
     8221 tttctaaata aaaactatcg taaggattgg cttctatttc gattgatatt ctactggaaa
     8281 tagtaattcc atatttttct aactgttcaa ccttgtcagg attatttgtc agtaaatgaa
     8341 gtgactgaag tcccagatct ttaagcattt gtgctccaat atgatattct cttaaatcac
     8401 cttcaaagcc taatgcaaga ttggcatcaa gcgtatccat gccttgatct tgtaaatgat
     8461 aggcttttaa tttattgata agtccaattc ctcgtccctc ctgtcgcaag taaagtaaga
     8521 cacccgaacc attctcaaca atcattttca tagctttatc gaattgctgt ccacaatcgc
     8581 aacgtaaaga gcctaaaaca tcccctgtta aacattcgga gtggatccga cataatacat
     8641 tggcttcatc ctctatgttt cccataataa gagcaagatg atgttcccca tttagtttat
     8701 ctatatagct aattgctttg aaattaccgt atctagtagg catattgaca gttgaaactc
     8761 gttctaccag ctgatcatat acttttctat attcttgtaa ttctttgatg gtaattagtg
     8821 gaatgttgtg tttcttcgag aactgaatta aatcatctgt tctcatcatt ttgccatcat
     8881 gattcattat ttcacaacat aggccacact cttttagtcc agctaatttt aataaatcaa
     8941 cagttgcttc tgtgtgtcca cttctttcta gaacaccacc tttttttgca attaaaggaa
     9001 acatgtgtcc tggcctgcga aaatcagagg gtgttatatc ttcagctaca cacatacgtg
     9061 cggtcagtcc tctttcctcg gcagaaatac ctgtggtcgt ttctttataa tcaattgaaa
     9121 ctgtaaaagc agtcttatga ttatctgtat tgttttcaac cataggtgaa agcattaatt
     9181 gattagctaa actttcgctc ataggcatac aaattaatcc tttggcataa gtagccataa
     9241 aattaacatt ttctgttgta gctgcttgtg cagaacaaat taagtctcct tcattttctc
     9301 tatccttgtc gtctataaca agaacaagtc gtcccttctg caatgcttct aatgcttctt
     9361 gtatttttcg atattccatt gactgattat cctttctgct aaaatccatt ttgatataat
     9421 agttccttag atatttctga ttttggagag ttatccatca gtttttgcac atatttacct
     9481 aagatatcat tttcaagatt tactgtactc ccgacttgtt tactcttaag aatggtttgt
     9541 tccaaggtat gagggataac agatactgaa aagtttactt tggagacttt agcgacagtc
     9601 agactaatgc cgtcaattgt aatagatcct ttttcaacta ttaaatctaa aatttctttt
     9661 tgtgtgttga tttgatacca tacagcatta tcatcttttt ttattgacga gatttttcct
     9721 gtaccatcaa tgtgtcctgt aacgacgtga cccccaagtc gaccgttgac agataaggct
     9781 ctttctagat tcacctcact tccatgtttt aatagagtaa gagctgttcg actccatgtt
     9841 tcattcatta catcaactgt aaaggattga tgattgaaat gagtaactgt aagacagata
     9901 ccatttactg ctatactatc gcctaaatgg atatccgtta atatttttga ggctttaatt
     9961 gatagtttac aattacgaga gtctttctgt attctttcaa cttttccgat ttcttcaatt
    10021 attcctgtga acatggataa atcacttcac tttctatgag atagtcattt cctatttgag
    10081 aaaatgcata aggtttcaat ctaatagcgt catttggcaa agaaatacct tcacctccga
    10141 caggaaactt ggcactacct ccaaaaattt ttggtgcaat atatattttc agctcatcaa
    10201 caatttgttg ttccaaagca ctccaattca ttagactgcc cccttctaga actaggctat
    10261 caatctgcat gtttcctaga tgttgcatta aactcgataa gtctatatga ttgccttttt
    10321 tctttatgga aagtatttca cagccatgat tttgatatag cttcatttta tttttgtctt
    10381 cagaggaagt ggcaatgtaa gttttaatat catttgctgt ttttacgatt ttagaggtaa
    10441 gaggagttcg taaatgtgta tcgcatatga tacggatagg atttttccct tcctccaatc
    10501 tacatgtcag caaaggatcg tcttgaataa cagtattgac tcccaccata attgcactaa
    10561 catggtgtcg taactgatgc acatgctttc ttgcttcttc ttcagtaatc catttggatt
    10621 gatttgtttt agtggctatt tttccatcca ttgacattgc atatttcata aaaacatagg
    10681 gtacatgctg ggtaatatac tttctaaaac tttttattaa gttaagacac tcattttcta
    10741 aaattccaac agtaacttga agattatttt cctcaagtat ctttactcct tttccagata
    10801 caataggatt acagtctagg cttccaatga ctactcttgt aataccacta tcgattatag
    10861 catctataca gggaggtgtt ttcccgaagt gacaacaggg ttcaagtgtt acataaagcg
    10921 tcgctccgac aggggattct ctacagtttt taagagcatt tctctcagca tgtgggccac
    10981 caaaaaactc atgataacct tgtccgataa tgtgattatc ttttacaata actgcgccga
    11041 ccataggatt gggattgacg taaccagccc ctttttgtgc cagttttatt gctaatttca
    11101 tatattttga atcgctcatc tcactacctc caaaaaaata tgccttgaat aggggactac
    11161 tcaaggcata caaaagaaaa cttatgcgat taacaaaaat gctctgaaat gacaagtaat
    11221 catttcagag cacgcaaaaa gcacaaatat acttttatct tctttcatcc agactatact
    11281 gtcggctttg gaatttcacc aaatcatgcc tttcggctcg tgggctatac caccggtagg
    11341 gaatttcacc ctgccctgaa gatagttatt caattacaga tgattatagt acttaatttt
    11401 gaatatgtca acagataaat accgattgtt tttgatatac tgtatttgtg ataatcgatt
    11461 ctcgctcctc ggataaagaa aatatgatat actagataaa cgaaataaga gagaaggaat
    11521 actatgtacg catatttaaa aggaatcatt accaaaatta ctgccaaata cattgttctt
    11581 gaaaccaatg gtattggtta tatcctgcat gtggccaatc cttatgccta ttcaggtcag
    11641 gttaatcagg aggctcagat ttatgtgcat caggttgtgc gtgaggacgc ccatttgctt
    11701 tatggatttc gctcagagga tgagaaaaag ctctttctta gtctgatttc ggtctctggg
    11761 attggtcctg tatcagctct tgctattatc gctgctgatg acaatgctgg cttggttcaa
    11821 gccattgaaa ccaagaacat cacctacttg accaagttcc ctaaaattgg caagaaaaca
    11881 gcccagcaga tggtgctgga cttggaaggc aaggtagtag ttgcaggaga tgaccttcct
    11941 gccaaggtcg cagtgcaagc aagtgctgaa aaccaagaat tggaagaagc tatggaagcc
    12001 atgttggctc tgggctacaa ggcaacagag ctcaagaaaa tcaagaaatt ctttgaagga
    12061 acgacagata cagctgagaa ctatatcaag tcggccctta aaatgttggt caaataggag
    12121 cagagaatga caaaacgttg ttcgtgggtc aagatgacca acccgctcta catcgcctat
    12181 catgatgagg agtggggcca gcccctccat gatgaccaag tattgtttga gttgttgtgt
    12241 atggaaacct atcaggcagg cctgtcttgg gaaacggtac tcaacaaacg ccaagctttc
    12301 cgagaagtct ttcatagcta tcaaattcac tcagtcgcag agatgactga cactgaattg
    12361 gaagccatgc tggagaatcc agctatcatt cgaaatagag ccaagctttt tgctacacgc
    12421 gctaacgccc aagtctttct acagttacag gcagagtacg gctcttttga tgcctatctt
    12481 tggtcttttg ttgaggggaa aactgtcgtt aacgatgttc ctgattatcg ccaagcgcca
    12541 gctaaaacac ccttatctga gaaattagcc aaagatctca aaaaacgagg cttcaagttc
    12601 acaggcccag tcgccgtatt gtcttttcta caggctgcag ggctagttga tgaccacgag
    12661 aatgattgtg agtggaaagg tcttaaatga tgtctaacaa aaataaggga attctgattt
    12721 ttgcgattct ctatacagtc ctctttgtgt ttgatggcgt taaattgctg gcttctttaa
    12781 tgccatctgt cattgcaaat tatcttgttt atgtagtttt agctttatat ggctccttct
    12841 tgttcaagga tagattgatc caacaatgga aggagattag aaagactaaa agaaaattct
    12901 tctttggcgt cttaacagga tggctctttc tcattctgat gactgttgtc tttgaatttg
    12961 tatcagagat gttgaagcag tttgtgagac tagatggaca aggtctaaat cagtctaata
    13021 ttcaaagtac ctttcaagaa caaccactac tgatagctgt ttttgcttgt gtcattggac
    13081 ctctggtaga agaattattt ttccgtcagg tcttattgca ttacttgcag gaacggttgc
    13141 caggtttact aagcattatt ctggtaggac ttgtttttgc tttgactcat atgcacagtt
    13201 tggctctatc agagtggatt ggtgcagttg gttacttagg tggaggcctt gccttttcta
    13261 ttatttatgt gaaagaaaaa gagaatatct actatcccct acttgttcac atgttaagca
    13321 acagcctctc cttaatcatt ttagctatca gtatagtaaa atgaaataag aacaggacaa
    13381 atcaatcagg acagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactattc
    13441 tagtttcaat acactgtaac atgtgatgaa aatgccagta atgataccga gaaaaaagct
    13501 gagaaacttt tcccagcttt atttgttata gtcaaagcga atgacttgtt cctgtgcatc
    13561 tacatgagca tggaccccaa agggtacaat tgctcttgga gttgcgtggc cgacattcag
    13621 attatagaca atcgggatat tgctgtcaat gatatctaat agtgcctctt tatagtcgtc
    13681 atggaaagtt tcatccatag gttttccgac caagagtcca ttgatgaccg cgaatatgcc
    13741 agtgtccttt aaagttagca acatcttttt gaagtcttct ggcttaggct tttcttcgct
    13801 tgtttcgagc aagaggattt tcccttccca gtctgacaag tcagggaaaa gtttgtattt
    13861 tgggcagagt tccgtgctat ctgcgtatcg agagttgtca aagatatcgt agagggattc
    13921 taggcaacca ccgaggattt tcccctcgaa ctgagcactt ccttgcaaca agtcaaaacc
    13981 tgtatttgta tgactgacac gaggtgttcc cagggccgtg ggactaaaat cagttcgttc
    14041 ctcataccaa acgtcactag ggcggatttc tgaaattctt cccgtctcaa tcaattcttt
    14101 aaagtagtga aggctatagg ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa
    14161 ggattgacca taaaaagtct tgattcctaa tttatgcaac atgaggtggt tcatggttgt
    14221 atccgagaag ccaagaaaaa ttttttgctt gataaccttt tggagttggt cattttcaaa
    14281 aagataaggt agcaagcgat aggtatcgtc tccaccgatg gcacatagga tcatgtcgat
    14341 gctatcatca gaaaaggcat gaatcaaatc ctctgcacga gcttcaggat ggtccttgat
    14401 aaagtctaat ccttttaacg aatggggcaa aaagatggga ttgagtccca gatccttgag
    14461 acgttggata cccaagtcca cttcgtgttt gacaaaatcc tctccgataa tgccactaga
    14521 taaactaaca ataccaatag tagaaaccat atctcatcct cctagaaata gattgagcct
    14581 attttatcac aaaatataag agaaagctat gtgggatttc agaagaatac ttttaatact
    14641 cttcgaaaat ctcttcaaac cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag
    14701 caacctgcag ctagcttcct agtttgctct ttgattttca ttgaatataa ctcaaaaaag
    14761 taagtgaaaa agcaaccgca cctgcagttg cttttatcgt tttcttattc ttgatagcgt
    14821 gttggtcctg cacttgcact acggatattc aagcgtttct tgagatagaa gcgaagggct
    14881 aggagggctg ctccaataat agctagtggc aatggatcca gtactgggtt aaggctagct
    14941 ggtaggaagc ttgttgcaaa gaagacaagc aaccaaagga acatagaagc taggataact
    15001 agtacagatt tccagaaagg tggacgttga ctgcgatcca tatctggtcc atagtattgg
    15061 taaacaaagt agtacatcaa gtagaaggca aatccaccaa ccagtccaac taatagaaga
    15121 gtaatcaatc catagccgaa agcttggtct gccgcaaaga aggttgtgag ggcgctgaca
    15181 agggcaaaga ggctagtgat gaaaagagct gagtccataa tcatcagttt tgggtcatca
    15241 ttttcttttg gatgctcttt ttcgtactgc tctttgacag tgaagctatg agcccaatga
    15301 gttggtgcgc cgtataggga acgggcagtt gtacctttag attgctcctc aaggatttgg
    15361 ggaatgactt cctcaaaaat agtctggatt tcagcgtctg ttttcccatc tttgatgaat
    15421 tgttgggtag caatgtggac aaactcttgg tttttcttag ttaatttttg tagatcaatt
    15481 tgagacatag gaactcctct tagaaccatt ttttatggat gagatagaga gtgagcgaga
    15541 cactcatagc aaaggcgata aagacgatta accagaaggc atttggctct ccgtttaggg
    15601 ggatttcatt atccttaaag ttcatcccgt aggcagaaaa gaccatggtt gggatggaca
    15661 tgacgatggt cacaagggcc aaggttttca tgatgttgtt ctggttgtta gaaatgatag
    15721 aggcaaaggt ctctgtcata gaatgcaaga cgtttccata aatatctgcc atctcgatgg
    15781 cctgttgggt ttcaatcagg gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga
    15841 tattgctggt tgaactggtc aatttcttaa tcacgcgctc atttgttttg agggaggcct
    15901 tgaaatagac gatagttttt tccaattcca tgagctcaat caattcttca ttacgagttg
    15961 attgatgcag ttgactttcg atttgttcac tcttgcggtc gattgaacga agggctgtta
    16021 ggtaaagctc tgcattgcga taaagaattt gaaagataaa acgtgaacgc atgaaggtat
    16081 agaaattacg caatcgacgg ttgataaaga catcaaggac aggtagtggt tccaaacacg
    16141 tagtgataat ggtttcctca gtgatgataa taccaagcgg gatggttacg tagtaggtgc
    16201 ggttatttct ttcctccgtg accggcacgt ctacgataat cagggtatac tcgtcttcaa
    16261 tggtaatacg agacatttct tccgcatcga gcggtgctcg aaggtcggca atatcaatat
    16321 cgaaggtgtt ggcgatttcg agtgattcat tttgagtcgg attgacgaga ttgatccaag
    16381 tacccggttc aagcgtatcg atctctttaa attcagttgt tgtagagaga aaaacttgtt
    16441 tcatatccct tatcctttct catttttcag attttttcac actgtactat tatactacaa
    16501 aatcggcctt tttcaaaata aatctaacaa aaatcctgtt gctattggat ttttactttg
    16561 tcttgaaatg ttgattttta aatttgctcc cctttttgct cccccctata gtgcttttag
    16621 tgcagtttcg tagaatgata ctgctttttt tgcgttctct tttgagaggt ggctatatat
    16681 atccatggtc attgataaag tggaatgacc taggcggtac tggagttcct tgtatggtat
    16741 tccagagtta agcaataaac tagcgtgagt atgacggaat ccgtgaaagc caatgttagg
    16801 aacatcagca cgcttaaaat gtgtttgcaa tcttctttta agtcttgaac tgctaggata
    16861 ctcatgaatg aaatcagaaa atactacact ttcacgttgc cctatcttcc aggcctcttt
    16921 agtttggcgc agtttgtact gctttagcat gctaacagtc gcttgatcta tatctatatc
    16981 ccgataacta gccttagatt ttgggctatt gatttctata tcccgattta gtgttttggt
    17041 aacatgtacc acggcattat ctaaatctat atcagaccag gaaagagcta aagcttcatt
    17101 gatacggcaa ccagtagcca ataggaactt atagagcgtt gtctcatagt aataacggta
    17161 tctatgagta tctaaattat cgagataacc aagaaacttt tttagttctt gattttcaaa
    17221 gtgttttacc ttttggcgct ttgctttctg agtgttacga ggtaaaacaa catcacgcgc
    17281 aggattggac ggtatagctt gcatggttac gccatactgt aagatacgtt tgtttaaagc
    17341 gtgtatcttg tcataatgta gaaaagcccc tttttcccct ctattagtct tatcagcaag
    17401 ttcgttgata atggactgga taagtggagt agtgagctta tcgagcttgt aagccccaaa
    17461 aataggcaat atatgattat cgattagctt tctgacattt ccttgagtgt ttggcttaac
    17521 tgtattctta taactttcta accagagatt ggctaattct tgatagtttt ttatggtgct
    17581 agccttttgt ctagtagatc ctgctttttg aaaagctatt ttttcttgat tggctttctg
    17641 ttttaattcc ttttgtgtcc gacctgttac cttggttttg actttctttc ctgttacctg
    17701 gtcaactcct agatatacat tagcacgata gactttacta ccgtcttttt ttataacttc
    17761 agttattttc atgatgataa acctttctaa aatacatcag caggcaagcc attatcaaaa
    17821 aggttttata tcatgctagg gcttcatagt ttgccctgta ttcgatttta agtagtcaga
    17881 cggtaaataa taccagagga gggaacaagg cggatatggc tagtattatc taaagtttta
    17941 aattcctgtt cataaaatta atagttaagt tccataattt cattaaattg tatagtttta
    18001 ctaactattg tggtaacttg ggcattgttc tatgccagtt tgcaggaaat cctaattcag
    18061 ttaaaaactt atcaattgag actgtaagta gatgtttttc aaatgtttta aatcttgata
    18121 gtaatgtatt atgtaactta gcatactcaa ttgaacttaa aaagcattgt aagactataa
    18181 aaacatggta agggctactt tttgcacaag aattactaat accatagtta gaatgtaaat
    18241 ctgaatagta tttaacactt ttcttacact taaagctaaa aagtctatta tcatgagcgc
    18301 atacatttct aacttctcca atattctcta caaaactaac aagtatagct ggtgtgaaat
    18361 ttatattaat tttaatatgc tcacaaataa aactataaaa cttttttgaa attttatctt
    18421 gtaaagaaat tgggagagtt tgtaaaattg ctaacatatc tccgaaagtc agataatcaa
    18481 ttattaccca aaatggtatt tcaagatgtt tactaaaata atgttgaata ctattcgctt
    18541 gtctacttga cttatgttta tctattattt taaccatttg acggatcaca aatttaatct
    18601 ttcgaacatt atcactattc gacttattat agttatttat atctaagtaa aaataaggtg
    18661 tagaagcaaa tctttcagaa aatacatatg caattgctga ttttatatgt ttttctgctt
    18721 ccaatattgc ttttaaaaaa gaatatttta tctctttgtc ataaaaataa ctgtaagtga
    18781 tttctgaaaa gtttgttcca ggtctatatt tatttggtga ctgttcaaaa tatttactgt
    18841 acccattgat aatactgtag taattgttag ttaatagata tttttttgct cttttataat
    18901 ctgtaattat taggccacgt ttatgaagca attctatttg ttctggaata gttttaaatg
    18961 gtttttgcaa aaaaaagcac ctccatatag aaggtgctat tttcgcgttc ccgtttcact
    19021 gagaataatc gggcgctaat tccttaagta ccttcattgt atgataattt taaatgttag
    19081 tcaacagttt tgttcaaaat aattgatttt tctttacttc gttttgttt
//
LOCUS       DAVEHY010000043        18960 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVEHY010000043 DAVEHY010000000
VERSION     DAVEHY010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.043"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..863)
                     /gene="lytB"
                     /locus_tag="VUZ44_001825"
     CDS             complement(<1..863)
                     /gene="lytB"
                     /locus_tag="VUZ44_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEU0320692.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGSFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGG"
     gene            complement(905..1843)
                     /locus_tag="VUZ44_001826"
     CDS             complement(905..1843)
                     /locus_tag="VUZ44_001826"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU0320693.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKVTNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1854..2654)
                     /locus_tag="VUZ44_001827"
     CDS             complement(1854..2654)
                     /locus_tag="VUZ44_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU0320694.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2904..3284)
                     /locus_tag="VUZ44_001828"
     CDS             complement(2904..3284)
                     /locus_tag="VUZ44_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU0320695.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3342..3701)
                     /gene="rplT"
                     /locus_tag="VUZ44_001829"
     CDS             complement(3342..3701)
                     /gene="rplT"
                     /locus_tag="VUZ44_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU0320696.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3753..3953)
                     /gene="rpmI"
                     /locus_tag="VUZ44_001830"
     CDS             complement(3753..3953)
                     /gene="rpmI"
                     /locus_tag="VUZ44_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU0320697.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3986..4516)
                     /gene="infC"
                     /locus_tag="VUZ44_001831"
     CDS             complement(3986..4516)
                     /gene="infC"
                     /locus_tag="VUZ44_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU0320698.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4532..4663)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4823..6004)
                     /locus_tag="VUZ44_001832"
     CDS             complement(4823..6004)
                     /locus_tag="VUZ44_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320699.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     gene            complement(6008..6595)
                     /locus_tag="VUZ44_001833"
     CDS             complement(6008..6595)
                     /locus_tag="VUZ44_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320700.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6628..6816)
                     /locus_tag="VUZ44_001834"
     CDS             complement(6628..6816)
                     /locus_tag="VUZ44_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320701.1"
                     /translation="MTATKSYKYDWNTVLEYSINYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYSGGY"
     gene            complement(6995..9235)
                     /locus_tag="VUZ44_001835"
     CDS             complement(6995..9235)
                     /locus_tag="VUZ44_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU0320702.1"
                     /translation="MLQWIKNFPIPLIYMSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFALSFLYPVIQLNFIFEWLEGMIRLVSKVASRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDIGQGESIFLRDMTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRNVTAGENLPIFGSQLEVLSPRK
                     IGDGDHEDSLVLYGKFLDKYFLFTGNLEEKGERDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9219..9860)
                     /locus_tag="VUZ44_001836"
     CDS             complement(9219..9860)
                     /locus_tag="VUZ44_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEU0320703.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTEKEVNKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQKAGG
                     LTEQADSKSLNLAQKVSDEALVYVPTKGEESASQQAGSGAPSSTSKDKKVNLNKASLE
                     ELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9928..10497)
                     /locus_tag="VUZ44_001837"
     CDS             complement(9928..10497)
                     /locus_tag="VUZ44_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320704.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     IFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10674..11099
                     /locus_tag="VUZ44_001838"
     CDS             10674..11099
                     /locus_tag="VUZ44_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU0320705.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            11100..11513
                     /locus_tag="VUZ44_001839"
     CDS             11100..11513
                     /locus_tag="VUZ44_001839"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU0320706.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            11459..11785
                     /locus_tag="VUZ44_001840"
     CDS             11459..11785
                     /locus_tag="VUZ44_001840"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320707.1"
                     /translation="MVDVAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(12152..12411)
                     /locus_tag="VUZ44_001841"
                     /pseudo
     CDS             complement(12152..12411)
                     /locus_tag="VUZ44_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12414..12914)
                     /locus_tag="VUZ44_001842"
     CDS             complement(12414..12914)
                     /locus_tag="VUZ44_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320708.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            12950..13129
                     /locus_tag="VUZ44_001843"
     CDS             12950..13129
                     /locus_tag="VUZ44_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320709.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(13107..14075)
                     /locus_tag="VUZ44_001844"
     CDS             complement(13107..14075)
                     /locus_tag="VUZ44_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU0320710.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14161..14376)
                     /locus_tag="VUZ44_001845"
     CDS             complement(14161..14376)
                     /locus_tag="VUZ44_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU0320711.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14385..15239)
                     /gene="cvfB"
                     /locus_tag="VUZ44_001846"
     CDS             complement(14385..15239)
                     /gene="cvfB"
                     /locus_tag="VUZ44_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU0320712.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15299..15856)
                     /gene="frr"
                     /locus_tag="VUZ44_001847"
     CDS             complement(15299..15856)
                     /gene="frr"
                     /locus_tag="VUZ44_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU0320713.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15865..16602)
                     /locus_tag="VUZ44_001848"
     CDS             complement(15865..16602)
                     /locus_tag="VUZ44_001848"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU0320714.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16686..18020)
                     /gene="trmFO"
                     /locus_tag="VUZ44_001849"
     CDS             complement(16686..18020)
                     /gene="trmFO"
                     /locus_tag="VUZ44_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU0320715.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEDTRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18265..18519)
                     /locus_tag="VUZ44_001850"
     CDS             complement(18265..18519)
                     /locus_tag="VUZ44_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU0320716.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            18514..18960
                     /locus_tag="VUZ44_001851"
                     /pseudo
     CDS             18514..18960
                     /locus_tag="VUZ44_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5480 a         4278 c         3515 g         5687 t
ORIGIN      
        1 ccaccggatt tgaagtagta ccaagcttga ctatgagaat cgtagaccca ttctttttca
       61 gctattttcc catcaaactt gaggtaaaac caagattcct tatcccaaat ccattcattg
      121 gctgccatgt agccaccgga ttttagataa taatagtgac cattctcgaa aatccattct
      181 ttatcagcat agtttccatt ttctttgatg taaaaccaag attggtattg tttgtcaaaa
      241 agccaacctt gctgtacttt ggcaccacta gcattcacat aagcttgatt aatccactga
      301 cttgtcagta gataaccacc ggatttgaaa taatagtcct tccctttaat ttggagccat
      361 tctttctctg cgtgctgtcc atctgctttg atataaaacc aagcatcgta ttgagaatca
      421 tagacccagt cttctattac tttggcacct gttgcaccaa cataggaagt tcctacccaa
      481 gcatttcttt tcatctttcc atcttggtca agataataaa aggatccctt gtcttctacc
      541 cattctgatt tggccatata gccaccagat ttgaggtaaa aatagtcgtc accttgcttt
      601 agccattcat tttcagcata gttagcatct gcttttatat agaaccaaga ttgataatga
      661 gtatcaaaaa cccactcatt cgctgcttga ctgccatctt ctttcagata ctgttttcct
      721 tgccaagtac catcactagc cattgcaccc tctggactag ctaagaaaaa tagcagagct
      781 aaaaaaataa atcttacttt cttcattaac cttcttcctc tgttcttatt tattttattg
      841 taccaaaatt ctcctaaatt catattacaa actaataaaa aatcaagaac agattgattg
      901 cagtttacct cagagactct tttacttcct gacggagttc ttccagactg ctaataccgt
      961 atttatccat gacttttggt aaattttcga tgatgtcagg gcaggcataa ggattggtaa
     1021 agttagctgt tccaactccg atagcagatg ccccagccag atacatttct agggcagctt
     1081 cagccgaatc cactcccccc attccaatga taggcaggtc tgttgtttgg gctacttggc
     1141 ggatgagttt gagggctact ggaaagactg ctggacctga cattccacct gttccattgg
     1201 ccaagattgg ttttctggtt ttgaggtcaa agcgcattcc aaccagagta ttgatcatgg
     1261 tcaagccact tgctcccgca tcttctgcag cttttgcgac agtaacgata tcggtcacac
     1321 tcggggttaa tttgacataa actggcactt ctgaggcttc cacagctgct ttcaccacat
     1381 cataagccaa atctggatct tgaccaatca aaagtccatg attacagtgg tcaacattgg
     1441 gacaagaaat attgagctcg atagctttta cattagttac cttggaaatc ccatgagaaa
     1501 cagctgcata ctcttgtttt gaaaaaccag ccacattggc aataatagga agatttggat
     1561 attctctttc cagccaaggt agcttttcag ccaaaacaac ctctaaacca ggattttgca
     1621 agccaattgc attgagcata ccagcaggcg tctctgccac tcttggagtt ggatttccaa
     1681 aacgtggttc aagggttgtc gccttgatca taatagaacc taaaaggtct aaatcatagt
     1741 acttggcata ctcttgtcca aagccaaaac agcctgatgc tggaataatc ggatttttca
     1801 aatccaaacc aggtagagaa acttgtaatc gatttgtagt cataattttc tccttataat
     1861 acaactgttc ctgtgcggaa aacaggacca tcttcacaga cgcgttggct gaccgtctcg
     1921 ctttctggta cttttagaac acaggcatag caagctccca tcccacaagc catacgagat
     1981 tccagagata aataggctct tgggtgatca tcaaaggttt gattgatata cttcatcatt
     2041 cctggagccc cacacgagta aacagcatca aactgactgt ctaaatcatt gataacaacg
     2101 gaaacatttc ccttgatgcc ataagaacca tcatctgtcg ttacaaagac ctgaccatac
     2161 tgagccaatt ccgttttcaa aataacagca tccttattag caaaaccgag gactgtcact
     2221 actttcactc cacgttcatg caattccttg gccacctcaa gcaagggtgg aacaccaatc
     2281 ccaccaccaa caaggagaac ctgattctgc tcatcaaggt cagacaagtc aaaaccattt
     2341 ccctgaggcc ccatcacatc aagagtgtct ccctgactta aggttgaaaa aattgcagtc
     2401 ccagctccct caatccgata aatgaggtga cactgcttgt ttgccttgtc aatagacgaa
     2461 attgaaatag gacgacgtaa gagatgggca tcgtctggta cacgcagatg aagaaattgg
     2521 cctgctcgca tggcttcaac catttctcct tctaggacta attcaaagat tgctggcgcg
     2581 atttcctctt gtgcaaccac cttcatggtt tccaaccgaa tgacacccaa acgcttctta
     2641 catgtgagat tcataacttt tcctccttaa attttaaggg gaccagataa agaaaagacc
     2701 ttgctagtgc aaggcctcag ttaaaatcgt acaacacaag agagcacact caaaaggtct
     2761 cctctagaaa attgcactat tcttttatct gacaccttgt gagtctctct ggactcccct
     2821 taaaggttga atttttatta gtatactctt tcagctaaaa aaagtcaagt agaaaacgaa
     2881 tattctactt aacttgcacg aaattatttt tcacgaatga cttcgacctt atatccatca
     2941 gggtctttaa caaagtaata gtttggtgta gttcctggta gaccatttgg ctcagtcact
     3001 tcatagcctt ttgcactgtg ttcttgatga agtgcctcaa gatcaggtgt actgagggcg
     3061 atatgggcaa acccatcacc aaccacatac ggaccgtgat cgtagttata agtcaactcc
     3121 aactcataat catcaccctc aagacctaga tagacaatcg tgaaggcatg gtctggaaaa
     3181 tctctgcgac gcaattcttt aaaaccaaaa gcatcttgat aaaatgcgat tgatttttca
     3241 agattttcta ctcgtaagca agtgtgtagc atttttgaag ccatatcttt ctcctttatt
     3301 tttaaaaaga ctggacaatc ctgttccagt ctcatcagtt gttatttacc aagttttgct
     3361 ttagctgcat ctgcaagagc tgtgaaagct actgcatcgt taacagccaa gtcagcaagc
     3421 attttacggt taacttcgat ctcagccaat ttcaaaccat gcatcaattg tgagtatgaa
     3481 agtccgttca tacgagctgc cgcattgata cgagtaatcc acaatttgcg gaagtcacgt
     3541 tttttctgac gacggtcacg gtatgcatag tagtaagagt tcattacttg ttcttttgca
     3601 gtacggaaca agatgtgttt agctccatag taaccttttg ctaatttaag aatacgttta
     3661 cgacgtttgc gtgatacaac gccaccttta acacgtgcca tattttattt cctccaaata
     3721 tttcctagaa ttgtttactt acagtcaagc tattatttca agcgagtaag cattgctttg
     3781 atacgtttgt aatctcctga atgcaccata gatgctttac gaagatgacg acgttgtttc
     3841 ttggtttttc cgtggaaacg gtgagaagtg taagcacgga aacgtttaag tccaccagaa
     3901 cctgtacgtt tgaaacgttt agctgatgcg cggtgtgttt tttgttttgg catgattttt
     3961 tctcctttat ttaactttct gacaattatt ttttgtcagt cgctggcgcc aattgcatga
     4021 acatttgacg tccatccatt ttagcacgtt gttcgatgat ggcaatatct tgagttgctt
     4081 cagcaaactc ggctaaaact tttgcaccaa tctctttatg ggtaatcata cgacccttaa
     4141 agcgaataga taccttaact ttatttcctt tttcaaggaa cttacgtgca ttacgaagtt
     4201 ttgtatcaaa gtcacccttg tcaatagttg gacttagacg aacttctttc acagtaacaa
     4261 cgctttgttt tttacgttgt tctttttgct tcttctggta ctcaaatttg aacttaccgt
     4321 agtccataat ttttgcaaca ggcggtttgg cttggggttg aatcaatact aggtcaacat
     4381 tagcgttatc agccaaagct tgcgcttcac tgagtggctt gatgcctagc tgttctccct
     4441 caagaccaat caagcgaact tcacgtacac gaatctcatc attgatgaat aagtcttgct
     4501 ttgctatggt tttcacctct tttgttttat tagagaaaaa caatagcgga ctcgtaaata
     4561 tacaagcccg cacgttatga tagcgtttct tcgaaacttt tcatccgtag ggccaggcaa
     4621 cttaatgtca caaggcgaga agctctcact tctgcttttc tcaactttta tatgatacca
     4681 agttttctag ctcttgtcaa gataaaaagt tattttttga aaagtttgtg tttatatttt
     4741 ggtttggttt tcgaatcaaa aagagagaac caagttgatt ctctccctat gttagttttt
     4801 ctttagcttc cctataggaa aactaaactt taaaaacttc ctttttacgt gaacttcccc
     4861 atctttcgat aaatagaatc cccactaaca aaaggataat caggcaagga agtaagacca
     4921 tccccatgct ccaatttaga tcgacattat caatctgctt agataatctt ccagataaaa
     4981 tctccactga acgcaagtaa gtaaagggaa tcagatgtgc aatcctttga agaggctgaa
     5041 ttgtttggat gccaaacaat aagccaacaa tcccaatgag tgaaagaaag aggacaggca
     5101 ttttttgctt gaaaaagtaa gcaatcaagt acacaacttc cacaatgacg ataaaggcta
     5161 agaaagctaa gagcaagcca ggaaataata catcttgtat tttcccaata gttacttctt
     5221 gattcactaa gctataaatt gggtagggat aatctaactg tccaaaacca cttatcagac
     5281 ttcccactag aaaagaaaag ccacagattc cgataaacag cacagttaca tatcccactc
     5341 caactccaag agaggatatt gcaaatgtca cttttgaaac aggatataag tgagctgtgt
     5401 ccagatgatt ttgatatctt tctgcaaata gttgtgttag cataaaaata attgcaacca
     5461 caaacaagct tgggatgata acctctaaaa tccagacaat ctgatcaatc ccgtgggtcg
     5521 gaaactccaa agtatgtgct tttatgttca agggatacag ggcttggtaa atcttccgtt
     5581 cgcggtcaac ccccattttt aagccagagc tagcagtcgg gtcatttgat acaaattcat
     5641 aattcttctc ttcatcttgc cactgcagat agtaggcctc tttccagcgc ccttctttta
     5701 ataaagtcag aatttctgtc tttcgcgtca aaagattttt ttgcacgtct aaattatttt
     5761 tagcaaactg gtattcctcc gagctggtat cagacatttg ggagagtttc tcttcatttt
     5821 cattgatagc cctctcgttg gctgcaatgc gactttccaa cctgctctcc aagctgtgtg
     5881 agtttgcagt ctgactattt aaataaaagg taacaccgag tacagatgca aataaaagta
     5941 agataatcca gtttaaacga cttttgaaaa cttttttcaa taaaaataga ctaacatctt
     6001 tcataaacta aacctcttct atctgcccct gatgaatggt tactactcta tcgcagatat
     6061 caaccaactc ttccttatag tgggaactta aaagaaccag ctgttcttgt ctatcgattt
     6121 gtgctagcct atcaaaaaac ttctgtcgat aatactcgtc taagccattt gtaatctcat
     6181 ccatgagcca gcatttggcc tgactgagaa aatacatagc aatcaccaag cgttgcttca
     6241 tgcctaagga atacttgcgg atgggaagac tgatatagtc agccatttcc cagtaggcga
     6301 tttcatctct caagtttagg tctgacttcc agatgttttt tatgagacga aggtagtcca
     6361 tcccacttaa gtttccatcc agccattcaa cgctctcata ataaaacaaa gaaggaggaa
     6421 ctgcgatatt tccactactt atgggaatta aattgctaat ggcacggaac agggtcgtct
     6481 ttccagagcc attgatagca agaagaccat aaaacctacc ctttttaaag gtgaaatccg
     6541 catcttgcaa gatgacttgt cgcgttttta aggtcacatg agtaagctgc aacatatcta
     6601 gccctccttt ttctcactct ttaagaatta atagcctccg ctgtaatagt ttatgacctc
     6661 ataacgagcg tagttccagc ctccgccaac tttatactca gaatagctgt aataacgaga
     6721 ccattccgga atccaagcat actgatggtc gtgatagttg atactatatt ccaaaaccgt
     6781 attccaatca tacttgtaac ttttagtggc tgtcacagca gatacactgg actgaagaag
     6841 accaatagat tataaactaa ctaataaaac aacttttgct gatttttaat gattttatat
     6901 cctcaatatt gaatacgttt tcattatacc atttttatca ttattatgca acaaattttt
     6961 agtttatttc actaatctac aacatttatc cttcctatcg aacactttcg attttccaac
     7021 tatccaaccc cttaaaacgt atagctcctt gctggtcagt tcgataaact ttgctattga
     7081 taccttccag tcgtgtcaat gtttcctgat gggggagttt cattcgattg ctctttccaa
     7141 ctgagataag agtaagctct ggtttgagtt tttctagaaa ggctggactt gatgattttt
     7201 tatttccttg ttggctagct ttcaaaacat ttactttcaa gtctggatag tgcttcagca
     7261 agtccctctc tcctttctcc tccaaatttc ctgtgaagag aaagtattta tccaagaatt
     7321 tcccgtatag aacaagggaa tcttcatgat ctccatctcc aattttcctt ggagatagga
     7381 cttctaactg acttccaaaa attggcaagt tctctcctgc tgtcacattg cgcaccttgg
     7441 tttgagttac ctgtagttct gccacaaatt ccttctgttt cagactgtct tttgatacta
     7501 gaatctcccc tacatggaaa gccttggtca cctctgacaa atctccaaca tgctccttgt
     7561 ccgtgttagt caaaattagc tggtcaatct tagctactcc tcgacttttg agatagggaa
     7621 tcaaggttcg ctgggcattg ctggtcgtca tcttttcttg ccatttttcg attttcttat
     7681 aagattctgc cttgccaccg acatctatga gaatggtttt accagtcata tcccgtagga
     7741 aaatactttc tccttgccca atatccagca tggtgatttc attttccagt ggatgcttgg
     7801 tcaggagaaa gagccctgta atcaataagc acaataccgt tagcttttta atattttttc
     7861 tcaaatcata tactaaagcc aaggaaatta acaacaagat taaaagccat gcattgggtt
     7921 gtccaaagac tagaggccta cttgccacct ttgataccaa gcgaatcatt ccctccaacc
     7981 attcaaagat aaagttcagc tgaatgactg gatatagaaa ggaaagggca aataagatag
     8041 acaagagcgg taagaagacc aagtcaaaaa gaaaggaaaa gacaaaggtc aagaggatgg
     8101 accaaggttg aaattccgca aaatagaagg acagaatggg caatatgccc aaggagatga
     8161 ctagactttc actagcaaca gccttgagcc cctccccttc tttgctggtc atggtcagga
     8221 taaaagcata agcacaggac aagactcctc ctgctgtcaa gaaaaagttt ggcatgacaa
     8281 taaagaggac aagcaccgtc aaggcaaaat tatccaagcc cttaacccca tgttgagcca
     8341 gtagcttttg caagagactg cgaataaccg atgctgaaaa tccagttagt cccgcataga
     8401 taagggaaaa gggataagtc agccacttca acttttcttg tgtcaagccc aatcgtaaaa
     8461 gtagtttctt aaatccgtcc atgaaaaacc ctacctgcat acctgacaag gcaaaaaggt
     8521 gaataattcc taaactggaa taaagctcat tcatctcctc aaagtcggtg tccagatgtc
     8581 ctagcaagag tcctgtcatg taattgcgca tagggtctgg gaagtgcatc ttaatccaaa
     8641 ccacagcctt tcgacgtaaa ctggacaggt tttcacctat atcccaactg ccaacctttt
     8701 ggagtgactg gattctttta atattgagtg tctggtaaat tccctgagtc ttcagatagc
     8761 cttggtagtc aaagccacca aaatttctct gcccttctgg ctccgaaagc ttcccttcta
     8821 gtcctatctc atgaaggtca gttaaagctt gaaaggcttc tttctcctcc tcggactgga
     8881 gtttataata gacttggaaa gcacgaccat cagacttacc acgaaaggac agactgtcac
     8941 cgttaacctt aatagtgtct ggtaaaatcc gtaccctttc aacagaatcc accaaatttt
     9001 gactcacttg actctgttgc caagtttgaa acagaaacca gaagccaaag actccacaaa
     9061 tcactagaac tttacctgct gatttccaag gaaattggat aaagaggcag actagcagaa
     9121 aaacaaaacc caacaaagca aaataggata ctgagaaaat ggcgtagtaa agccaaagta
     9181 acagaaagct catgtaaatc aggggaatgg ggaaattttt aatccactgt aacataatct
     9241 ttaagctttt ctatggtctt tgcaccaatt ccagatacct tcttgagttc atcaaccgac
     9301 ttaaatttcc catttgtttc acgatggtcg ataatgtctt gagctcgttt tcctcccaga
     9361 cccttgacct gcttgagttc ttccagactg gccttgttga gattgacctt cttgtccttg
     9421 cttgttgaag aaggcgctcc agaacctgcc tgttgactag ctgattcttc tcccttagtg
     9481 ggaacgtaaa ccagagcctc gtcactaact ttctgagcta gattgagcga cttactatct
     9541 gcttgttctg tcaagccacc tgctttctgc acggcatcat tgactctact acctaccggc
     9601 aaatcgtaaa tacctggaga tttgacagca cctttgacat ctactgtgat tagatcttgt
     9661 tcaaggggtt cttccttgtt cacttccttt tcggtcgatg aatccttgga aacagctgca
     9721 acttctgcct gcaaattcgt ttccttgaca ggtgtttgtg gagctggctt tagcaggaaa
     9781 aatccgccta caagcaagcc cagaccagta cagatgacga tgattttata ctctttgatt
     9841 ttctcgataa ttgcttccat attttctcct ctcttagatt attcgtaaga ggaagaaaaa
     9901 acagtcgaaa aatttctttt caactgctta tttatttgca aaatagtctt ccttggtcaa
     9961 gacataatga actcttgtca cgattcggcc tttttcatgc tggtccatac aagcatatgg
    10021 ttctgcatgg gaaaaacgca tgcctgattt ctccatgacc tttcctgacg caggattgtc
    10081 cttatcgtga agggcagtca acttattcat ccctatcttc tcaaaagcta gctcaatcac
    10141 agcacgattg gcttctgtcg ttaatccttg attccaatac tttttattga taatgtagcc
    10201 aatagctgcc ttcttaagaa cagaatcaat cttgtgcaag tcaatggttc caataaactg
    10261 accattgctt tttagttcta ttccccaacg tcccaaggga ttagccaaat agaactgagc
    10321 aatgttattc ttggtttctt ccaagctttg attggttgga aaaatgtaac gtgtattacc
    10381 cttgtccgag gcatagtcaa acattgcttc cgcatcatcc aaagttacag gtctaagcaa
    10441 taaacgctcc gtttctatag acggatactg ggcaagtttt acaaaaattg attccatact
    10501 tttccaacca atcaaagctt gattttcact agtctagcat aaaaaatttg gatgacaagt
    10561 ttttcttgat ttttgaagcg gtttcatata caatgaaacc gtcacatttt tgatttatga
    10621 actggaatgt gacaaccaaa acaagaccgt caattgaaag gtaggttatc tcaatgttaa
    10681 tcggaatccc aaaagaaatt aaaaataacg aaaaccgtgt cgccctcaca cctgcaggtg
    10741 ttcatagctt agttagtcgt ggtcatcgtg tccttatcga aacaaatgct ggtctcggtt
    10801 ctggctttac tgatgctgac tatcaaaagc aaggagctga gattgtcgct actgctggtg
    10861 aagcttgggc agcagagttg gttgtgaaag taaaagaacc tttaagttct gaatacggtt
    10921 acttgcgcga cgatcttctt ctcttcacct acttgcacat ggccgctgct ccagaattag
    10981 cagatgctat gttagcagca aaaacaacag gaattgccta tgaaactgtt cgtgacaatc
    11041 aaggacaact accgctcctc gttcctatga gtgaggttgc aggtcgtatg gctgtttaaa
    11101 tcggagctca cttccttact aagcaagctg gtggctctgg tgttctacct ggtggtgtac
    11161 caggtgttcc aaaaggaaaa gtaactatca tcggtgatgg tgtcgtcggt acacatgctg
    11221 cccgcatcgc ccttggtctt ggtgctcaag tgactatttt agatattagt gccaagcgtc
    11281 tctcagttct agaagaagtc tttggaagtc aaattcaaac tcttatatct aattcattca
    11341 acattgaagc aagtgtgaga gatgctgatg tggtgattgg agccattctc atccctggtg
    11401 caaaagcacc ggaattggtg acagatgaga tggtcaaaca aatgcgtcca ggctctgtat
    11461 cgttgacgtt gctgttgacc aaggtggcct tatcgaaaca gctgaccgtg tgacaacgca
    11521 cgatgaaccc gtctatgaaa aacacggtgt tctccactat gccgttgcca atatccctgg
    11581 tgcggttgcc cgcacttcaa ccatcgccct aaccaatgtc actcttcctt atatcgaagc
    11641 tttggctggc aaaggattcg cacaagcaat ctctgaagat gaaggcttgc gtcaaggtgt
    11701 gaccacttat caaggttact tgactagcct accagttgct caaggactta atcgtgacta
    11761 cactgatatc aatgatttag tataaatttt gaaaagaaaa gggtgacttc gcaagtccta
    11821 cccactgtgc tttgtgtcat cagctattac atcgttggtt tattgtactg tagactttgc
    11881 aactggagac tttcgttcca gactcaattg tgcataagaa actctaaatt gaataaagtc
    11941 aacagagttt cgcccaacca cttcgtcttg taatgacaat tatataaacc aaaggaagct
    12001 gagctcttta gtcccagctt ctttttatat ataaaatttt acccgtgcaa agacagggcc
    12061 ttagcagact tcttttttac ttcgttcacc cttgcttttt ctttttaggt ttgggcgttg
    12121 gcagttggtt atacatagct aaaatcaggt cttatagaaa catcttatta tcaagttctt
    12181 ccactcaaat catttctttg gcacctttgt atggaaactc aaaagaagat tggtcaatct
    12241 tatctaagac tgcttgcacg ggtttaacta aaagcgatcg tcataaatac cgccaataat
    12301 cttgccgcgg aagtaaagaa tatactcccc catcatggaa cggtaagtca catcatctaa
    12361 tcctgataat tgttccaaaa caaattccaa atagttctta cttgatgcca tttctaatct
    12421 tctaggctct gttcaacgat aacaaccgta tagagttctt gcttaacctc gcatccaatt
    12481 gatttaaagc cctgcttttc ccaaaaatgc tgagattgcg gatttccctt aacataagcc
    12541 aaacgtgcct ttcgaaagtt cttagcaaaa taagctagtg cttctgtcac aatatgacta
    12601 ccaatccctt tcctctgata ggcttgatca accataaaca aaccaataaa aacagtctcc
    12661 tcatcaggat atgcatagac aaaatccata acagccacaa ggtcagatcc attccaaaat
    12721 ccaacaaaaa acttatcagc cttagcttta ccttcaggta gacaaagcat gtcctctttt
    12781 acagttgcaa aatttggttc tggtggacaa tgctgaaaat acagaggatt actttcatat
    12841 aaagataaaa tacttggaat atccttttca gttagtatcc tacaactgta atacttagat
    12901 agttggtcaa tcatcttttc aaattcctac tttcttgtgc cctgtgatta tgacacagga
    12961 agatgcactg atcgtcatca gccacataaa agttctttcc atcgtgccta atcgttgtct
    13021 cagacctttg gataaaacct ttagcctata caactggatt ttcctctctc aaaagtatat
    13081 tcttttgcag gcgaacttcc tcaaaatcag tcgtgtgcaa cttcagtaga atattcatag
    13141 gctcggataa tctgagcgac aactggatgg cgaaccacat ccttggctga aaaatgaaca
    13201 aagtcaatct gatggatgtt cttgagtttc tcttgagcat caatcaaacc ggacttgaca
    13261 ttacgtggca ggtcaatctg actgatatct ccattgacaa tcatcttaga atgaaagcct
    13321 aaacgcgtca agaacatctt catctgcatg atggtcgtgt tttgcgcctc atcgagaatg
    13381 acaaaggcat catccaaggt ccggccacgc atataggcaa ggggcgcaat ttcgataatt
    13441 tcacgctcca tgagacgagt cgtttggtct ttcccaagaa tttgatacaa ggcatcgtaa
    13501 acaggacgaa ggtaaggatc caccttctcc ttaagatcac ccggaagaaa tccaagactc
    13561 tctcccgctt ccaccgctgg acgagttagg ataattcgct tgacttgccc acgtttaagg
    13621 gcagtcactg ccaaggtcac tgcaaggaag gtcttccctg tacctgctgg cccaattcca
    13681 aaggtcacat catgctgttt gacactgtcc acataaagct tttgccctag ggttttgaca
    13741 cggataggtt tcccagtatt atctttgata atttcttctt cgtaaagggc gacaaacttg
    13801 tcaatttcat catttttgac catgctaatc gcagtgacta catctggcgt accaacggtc
    13861 atcccacgat ttaccaagac catcaaagcc tgaataactt gacgggcttc ctcacaggca
    13921 gactcttctc ccaaaacctg gacaatctcc gtacgagcat gaatcacaac atcaagctct
    13981 tcttccatca aacgaagatg gcgttcattg gaaccaaaaa gatgaaacag gtcatctgga
    14041 tgactcagtt gaatgtctat tgaatgttcc ttcaaataaa gaacctctct aatcctttta
    14101 tttcttttta ttatagcaga gggatggaga aattactagc ccaaacccaa tgaataaatg
    14161 ctagtgttct agatattcct gccaaatgct atcaaaatct cctaggttaa aagagaaact
    14221 ggcatgctcc tccaaaaagc gactgacctc atcaaaatca tctgtatgtt ttggaaaagc
    14281 tgcctcttca aaagcgaggt ctgccaaaat tgctttggga ctgttacttt taggattgcg
    14341 ctcggtcatg agccaagtgt aaaatgattt tctcataagc ctccctaaat caactctgtc
    14401 ccaaactggt cctgcttgat tttaccagcc ttcataagac cacctaaagc tttcttgaac
    14461 tgacctttag aaatgccaaa ggttgccttg atgtcgtctg gagatgactt atcatttaag
    14521 gtcatgaaac cgccattact ttccaaataa gtcaaaatca tctgagcatc gttttccaac
    14581 atttcaaagg agcgtggttt gagggagagg ttcagagtgc ggtccacttc acggaaacca
    14641 ataacgcgcg catctaatac ttgccccaaa cgtggctctg cgtaacgctc gctaggatga
    14701 ataaaaccaa gcatattatt ttctggtagg taaacaaaag ttcctgacag cttgagacgg
    14761 taaacaatgg ctggccagtt ttggttctgc atgttgttgt aagcaggacg agcaagacgt
    14821 tggaagtctt cttgataagc caagaggccc cagatacggt ctttcttatc cacttcaaga
    14881 cggatgtaga gttggtcgcc cttcttaggc cagagttcct tgagctcagg gagaatatcg
    14941 agtgacacaa cgatttcctt gtcaggaagg cctgtatcca caaagacacc caaatcctta
    15001 cgaacctctg tgacacgtcc ccaaccaaat tggtcctgag tggcagtcac ttctaaggtt
    15061 gtcaggcgga gtttttgctt catatccgtg tatgcaaaac ctttgaccgt atcccctact
    15121 gtatgttgac cttcttcctt agcaagagca taggtttgac catccttttg cacaaagtaa
    15181 aaacggtcat tttcatcgat gatcagtcca acgataaaac ttgcaagatt tgtattcata
    15241 tttccttctt tcgaataaaa ctcagccagc aatgccaact gagtttttct gtttattttt
    15301 agacttccaa aagttctttc tctttgttag cagtcatgtc gtcgatgtgt ttaacagcat
    15361 cgtctgttac tttttgaatg tctttttcaa gagtcttcaa ttcgtcttca gtgatttctt
    15421 ttgctttttc ttgtttctta gcttcgtcca tagcatcgcg acggatattg cgaacagcca
    15481 ctttagcatt ttcgccgacc ttcttcactt ctttagcaag gtcacgacga gtttcttctg
    15541 taagagctgg gataaccaag cgaatcacag aaccgtcatt agccggtgtg ataccaagat
    15601 cagaagcgtt caaggcacgt tcgatgtctt tcaatgaaga cttgtcaaat ggtgttacca
    15661 acaaaacacg cgcttctgga atcgtaattg aagcgatttg gttaagagga gtttcgactc
    15721 catagtattc tacatgtata cggtcaagca agcttgcatt ggcacgacca gcacggatac
    15781 caccaaattc acgagcaagt gattggtgag actgggtcat tctctcttta gctttttcaa
    15841 taattacgtt agccatattc tttcttattc cttttcttcg atattatttg aaactgttgt
    15901 tccgatattt tcaccaaata cgacacgttt gatgtttcct ggttggttca tgttgaagac
    15961 aaccaagtca atgtcgttat ccattgagag ggttgaagct gttgagtcca tgatacgaag
    16021 acctttgttg ataacatcac ggtgggtcaa ttcttcaaac ttaacggctg tcttgtcctt
    16081 cttaggatca gcattgtaca caccatcgac gccattttta gccatgagga tggcatctgc
    16141 ttcgatttca gctgcgcgaa gagccgctgt tgtatctgtc gagaagtatg gtgaaccaat
    16201 tccagcacca aagataacga tacggccttt ttcaaggtga cgaagggcac gtccacggac
    16261 ataaggctct gccacttgtt gcatggcaat agctgtttgt acacgcgtat caaccccaac
    16321 ttgttgcaat gaatctgcca tcacaagagc attcataaca gtcccaagca ttccagtgta
    16381 atctgcctga acacggtcca tacctgcttc tgctgcaggt tctccacgcc agagatttcc
    16441 tccaccaata acaagggcaa tttcgatacc taagctatga acttcttgaa tctcttttgc
    16501 gattgtttga actgtttgga tatcaatccc tacgccacgt tcaccggcaa gggcttcacc
    16561 tgataacttg attaaaatac gtttatactt gggattcgcc attttcactc tccttctttc
    16621 atcctaccta ttttatcaca atttctaaga tttttatagt atcatgaaca attctttcaa
    16681 aaaaattaga cagtcaaaaa ttcctctaag tcggcaaggg cacgctctgc aattttttca
    16741 taacgagcct tcttatcacg gatacgctcg ccttccaact ccttgatgat cccaaaattg
    16801 acattcattg gttggaaatg tttgctgtcg gcatgggtaa tgtaatgagc taagcttcca
    16861 atcgctgtcg tctcggggaa aataacctcg ctttcttcct tgaagagacg agctgcgtta
    16921 attcccgcaa ctaagcccga agccgccgac tcaacatagc cttccacccc cgtcatctga
    16981 ccagcaaaga agagatttgg ttgtttcttg gaacggtaag tctgctcaag aagatttggt
    17041 gaatccatgt aagaattgcg atgcatgaca ccataacgga caaactccgc attttcaaga
    17101 cccggaatca tttggaagac acgcttttgt tctccccatt tgaggtgggt ctggaaacca
    17161 acaatattgt ataggctacc agctgcatta tcctgacgaa gttgcacaac cgcataaggt
    17221 gttttaaatt ctccatcacg aggtcctgtg tagtcgtccg gatactcaag accgactggc
    17281 ttcatagggc cataaagcat agttttaatg ccacgtttgg ccataacttc gattggcata
    17341 catccttcaa agtacttttc tttttcaaaa gaattgagcg gtgcttcttc cgcattgacc
    17401 aaggcttcat ggaaatccat aaactcttgc ttggtcattg gagcattgag ataggctgct
    17461 tctcccttat cataacgaga tttgagatag accttactca tatcgatagt gttgacatcg
    17521 ataataggcg ctgctgcatc gtagaaatag aagccatcgc cattattaag ggcatgaatc
    17581 ttttcagcca gggcatcgct agtcaaggga ccagtcgcca caactgtaat aacatctgtt
    17641 ggcaattctg taatttcatc acgcaccact tcaatcaagg ggtggttgac cactttttcg
    17701 gtcaccattt gagagaaacc atcacgatcc accgcaaggg ctccaccggc aggaacacgt
    17761 gtatcctcag cagattccaa gataacagaa cccaagcgac gcatttcttc cttgagaaga
    17821 ccaactgcat ttgtcaaagc atccccacgc aaagaattgg aacaaaccaa ctcagcaaaa
    17881 ttgtctgttt tgtgctgagg agtcgacttg acaccacgca tttcataaag tttaactgga
    17941 ataccacgct ctgcgatttg gtaagctgct tcagaacctg ccaaaccagc accgataaca
    18001 ttgatataag attgagacac gacactaata cctctttggg agtgtgaagt taagattcac
    18061 attgaaaaag ccaatcagac ttacgagctt tcgagtttct tggctcaggc tgaaaaagtc
    18121 cacaggactt tttcactccc acaaatcttt ctattttttc ttctactagt ataacaaaaa
    18181 aagggaagaa ggcaaacttc cctgtttagt cattttcttg atgtaaagag atagtgagta
    18241 ttccagttaa gaatcaatta tatgctactc tataaaatct tttccacata acggatcgat
    18301 agggactgtt attctatctc ttgctataac cgtattatct aaaacagcat aacattcaac
    18361 atagtgatct cctttaaact gtgaatcttc gtgatatttt attttacctg aaaaaatagc
    18421 accacgctca caatttcttc taatagcctc agcttcaata tttcttactt tccaatagac
    18481 ttcctgcgaa acaaaatatg gtatagtagt tctatgaatg atgaagcaag taaacaacta
    18541 actgatgcac gatttaagcg ttttgttggt gttcagcgca cgacttttga agagatgtta
    18601 gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa acctaaatta
    18661 agcctagaag accttcttat ggctactctt caatatgtgc gagaatatcg aacttatgaa
    18721 gaaattgcgg ctgattttgg tattcacgaa agcaacttac tccgtcggag ccaatgggtt
    18781 gaagtaactc ttgttcaaag tggtgttacg atttcaagaa ctcctctcag ctctgaggac
    18841 acggtaatga ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaag aattagcgaa
    18901 tgattctggt aaaaagaaat ttcacgctat gaagactcaa gcgattgtca caagtcaagg
//
LOCUS       DAVEHY010000044        18747 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVEHY010000044 DAVEHY010000000
VERSION     DAVEHY010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.044"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(27..1376)
                     /locus_tag="VUZ44_001852"
     CDS             complement(27..1376)
                     /locus_tag="VUZ44_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU0320717.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQVVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(1389..3542)
                     /locus_tag="VUZ44_001853"
     CDS             complement(1389..3542)
                     /locus_tag="VUZ44_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU0320718.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(3922..4413)
                     /locus_tag="VUZ44_001854"
     CDS             complement(3922..4413)
                     /locus_tag="VUZ44_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320719.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            complement(4394..4990)
                     /locus_tag="VUZ44_001855"
     CDS             complement(4394..4990)
                     /locus_tag="VUZ44_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU0320720.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(4987..5469)
                     /locus_tag="VUZ44_001856"
     CDS             complement(4987..5469)
                     /locus_tag="VUZ44_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEU0320721.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(5466..6602)
                     /locus_tag="VUZ44_001857"
     CDS             complement(5466..6602)
                     /locus_tag="VUZ44_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320722.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
     gene            complement(6609..6905)
                     /locus_tag="VUZ44_001858"
     CDS             complement(6609..6905)
                     /locus_tag="VUZ44_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEU0320723.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(7435..8328)
                     /locus_tag="VUZ44_001859"
     CDS             complement(7435..8328)
                     /locus_tag="VUZ44_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0320724.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(9082..9312)
                     /gene="blpU"
                     /locus_tag="VUZ44_001860"
     CDS             complement(9082..9312)
                     /gene="blpU"
                     /locus_tag="VUZ44_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU0320725.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(9515..9805)
                     /locus_tag="VUZ44_001861"
                     /pseudo
     CDS             complement(9515..9805)
                     /locus_tag="VUZ44_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(9851..10084)
                     /locus_tag="VUZ44_001862"
     CDS             complement(9851..10084)
                     /locus_tag="VUZ44_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU0320726.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(10090..11082)
                     /gene="plsX"
                     /locus_tag="VUZ44_001863"
     CDS             complement(10090..11082)
                     /gene="plsX"
                     /locus_tag="VUZ44_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU0320727.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFVVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(11079..11849)
                     /gene="recO"
                     /locus_tag="VUZ44_001864"
     CDS             complement(11079..11849)
                     /gene="recO"
                     /locus_tag="VUZ44_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU0320728.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(11846..13015)
                     /locus_tag="VUZ44_001865"
     CDS             complement(11846..13015)
                     /locus_tag="VUZ44_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU0320729.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            13164..14174
                     /locus_tag="VUZ44_001866"
     CDS             13164..14174
                     /locus_tag="VUZ44_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU0320730.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(14365..14802)
                     /locus_tag="VUZ44_001867"
     CDS             complement(14365..14802)
                     /locus_tag="VUZ44_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU0320731.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(14887..17520)
                     /gene="polA"
                     /locus_tag="VUZ44_001868"
     CDS             complement(14887..17520)
                     /gene="polA"
                     /locus_tag="VUZ44_001868"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU0320732.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDQ
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            17776..18126
                     /locus_tag="VUZ44_001869"
     CDS             17776..18126
                     /locus_tag="VUZ44_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU0320733.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREDDTH"
     gene            18341..18457
                     /locus_tag="VUZ44_001870"
     CDS             18341..18457
                     /locus_tag="VUZ44_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU0320734.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            18450..18683
                     /locus_tag="VUZ44_001871"
     CDS             18450..18683
                     /locus_tag="VUZ44_001871"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320735.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLASEVASQQLGMSVSEFEALL"
BASE COUNT         5808 a         4229 c         3118 g         5592 t
ORIGIN      
        1 attatttaac tctaaaaaca cgaacattac tctttgttca aaaattgatc caaataataa
       61 cgtagataac ttttcttgcc cgtaatcatc tgcaagcggc cttccacccc gtacctaagt
      121 ttttcagcct gctccgaagt tagattagtc tccgcctcga ttttaaagaa attccctttc
      181 tcagtcttag tagctgtcgc atcaatactt gtaatagtag aatctaggaa aagttgattc
      241 ccggcatcat gagtcgtagt atagcgaaca gaatcaccga ccttgattct tgctacatct
      301 tttgaactta gataagctgt gagtttggct ttaccttctc tttccaaaga tggataaagt
      361 tgggctagta gggcaccttc tgcaaccatg ctagaatcac tggtctcagg attaagatga
      421 agcaccccat cctcactcgc cgtaattttc cccttgtcta aaagatttcc ctgtaccttc
      481 ttacctgact ctgcctccaa gattttctgg gctagaaggg tcaattcctg accaaccttt
      541 gccaagtgtt gggatttaag ggattccaat tgactgctta accctgacgc ataggcttgc
      601 tgggtacctg aacctgcata ctggacacgg taagtagcaa gactagattc taactgagaa
      661 atctgtgctt caacctgtgc aactacctga accttagttt ggggattttc ctcgccctga
      721 gacttgtagg actgataaaa agagtaggct agattctgac cggccaagga agcacctgtt
      781 tcaatagctg acttagctgt ctggtaatcg cgaattttag cctctgtttg actgatgagg
      841 ttgccgattt cggcttgggt ttggctagct gctgcattct gggacgcgat ggtctcattt
      901 tgttgcgatg tactagccct aagactgcct gcttgactga tgtagtcgcg aaaggtggct
      961 tggtagccaa acttatcctc ctctggaaag tggttctccc cttcttgcag gctcttttgc
     1021 agatactcca attgcttttt ttgatccttt agcatgtcca actgactggc ataggactcc
     1081 gcttggacac cctctgcccc ttcttggtat tgaaccaaaa gatccccctt cttaaccagc
     1141 ttattttctt ccaaatgatt gacaagaata cgattgttgc tagttgactg gatatttgca
     1201 aggatacgac tgggttcgac agtagctcta gtggacaaac tcatctcctt ctctgcaaca
     1261 gttgcaaagc caagtaaaaa cacgagcaga agggccatgg gtacaatcac actactggaa
     1321 aaattatggt aacgacgatt ataaaactcc gcactttcta aaaattctgg tttcatcctc
     1381 tcctctttct agctattgac caaatgggcg taaaagcctc cctgtgcaag caaatcagca
     1441 tgctttcctt cttcgacaat cttgccctga tccaagacaa ccaccttctc tgtccgctca
     1501 gcaatagtca agcggtgagc aatgaaaatc aaggtcttgt ccaaagcaat gagattatcg
     1561 acaatccgct tctctgtcaa aatatccaaa ctgctagtcg cctcatccaa aatcaagacc
     1621 ggcgcatctg tcaagagagc acgcgccaaa gcgattctct gacgttgacc acctgaaatc
     1681 cctgccccat ccgaagtcaa ttctgtctga taattcagtg gcatgcgctc gatatcctct
     1741 cgaatctctg ccaattcgac cgcccgtaag atatcttcct gtgtcgtccc ctccttggct
     1801 cccaaaagaa gattctccaa aatcgttccg ttaaagacat agggctgttg aggcagatag
     1861 ttgatgtact ggcgcagggc ttttttatca atctgattga gattgacacc acccagacta
     1921 atctcccctt gacttgggtc gtaaaaatta accatcatct tggccaaagt cgtcttacct
     1981 gaccctgaaa tccccacaaa agccacctta gacccttggg gaacggttaa attgatatcc
     2041 gacaagacgt ctcgaccata gccatacttg taatgaacct gcttgaaggt catatctccc
     2101 ttcatcaagc tcaaatcctc aactgttttc ttctcctcaa actcagaagc tactagatac
     2161 acttcattta gacggttatt ggcaacctgc gctgtctgaa gcttggtttg cagattgatg
     2221 atattttcca aaggattggt aaagtaaacc agcaaggtat tataggtaat caactgcccc
     2281 aaactcatct tgccatccat gaccagaaca gcccccatcc agagaatgcc gacattaagc
     2341 aagagatggg caaccttttt cagagccttt tgctgactct ctgctcgact ataggtaaag
     2401 gatttcttca gataatccac aaattccttg tcaatttttt ggtaacgctg actttcactg
     2461 gtcaaggact tgatagtctc aataccgttg atgtcctcaa tgatagaaga agacagaacc
     2521 gcattggctt ccatggtatc ccgattcatc ttttcaaacg gcttcataaa ggcaaagata
     2581 atcactgtgt agataggaag cgccaataaa gtcatgaaaa agagattggt attttgtgaa
     2641 aatagaacaa gggaaataat gacaaccgtt gacacatcta ggaaaatcga aaggatggtc
     2701 gaagccagcg catcgatgat actgttagca tctgtaaaac gagacacgat ctcccctgtc
     2761 ctgcgtgtcg caaagaagga catagggagg tgaaaaacat gcttgatata ggacaaaatc
     2821 acgtcaatcg acaagcgttg ccccaaaaca agcaagagat actcctgagc gtaagacaag
     2881 atttgctgga ggatgtagac gatgactagc ccaatagaaa taatccctag tgtcgaacgc
     2941 atctgatctg gcacataggt atcaatgata gactgcagat aataagaacc cacaatgtta
     3001 atcacggtta ccaagagtgt tgccaaaacg atattggcaa tcaagccacg ctgcttcact
     3061 aatataggga taaaagagag cagaccattt ttttgttcct tatgaggctt atagtctgga
     3121 ctaggtgcca taaaaagagt cactcctgtc cattcttcct caaaacgctc acgtggcagt
     3181 ttagtcaact tcaccccggg atctggatcg gcaatatgaa tgctatcctt atcctgcccc
     3241 gtcaccacat agtagtggag caatttccct tccttaagca catgggcaac aaaaggaaaa
     3301 gtcaaatccg gcaagtcaaa aagcgtcata tccgccttaa tggctcgcgt ctcaaaacca
     3361 atctcctctg ccaccttgac caagcccaaa gccgtcgtcc catccatggt cgtcttagcc
     3421 aattctcgca agtgagccaa aaaataataa ctaccatagt agccaaaaac catggctaat
     3481 gaagctacac cgcagtccat ctgatccact tgcggacgat agtgacgttt cccaaatttc
     3541 atattcatct ccttttccct aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
     3601 cgcaggctgc tcaaaacact gttttgaggt tgtagatagg actgacgaag tcagtcacat
     3661 atatacggca aggcgacgtt gacgtggttt gaatttgatt ttcgaagagt ataaactcat
     3721 ctgataacaa ctatcttacc ccaatcacta aacaaaaact ggacttcctt cccaaatgag
     3781 cctatctccc tcccaactgc actttttgga taaaaaaata ggcagaacaa acgttctacc
     3841 tagaaaatat aagaattaca agttaacaaa accgaaatga tttcatatca ttattaagta
     3901 aagaaaaaaa ttttagtatt tctaaaaact atttataata gacattatag cattaaataa
     3961 aaatggtaca gaaaacacta ctgtcaatct taaattttta aatctcgcat aatttgttat
     4021 cccaattagt aatactgtca atacgctgaa ataggcaaac tttatatccg atggattaaa
     4081 taaataacaa agtaaaatgc taaaacttaa ggttatattt ttagataaaa gaatatctcc
     4141 aaagttcctc ttattcttat caaaaaataa tgtaatcaga aagagagaaa atccatattc
     4201 aataagagtt gctataaatg tgaaaacaac agaaatcact gtcaatattg tttctatttt
     4261 aattgtaaaa agattagata gttcagataa tttatcaatt tgttcatcta aaattcccga
     4321 cttcatcagt aaatcaataa acaaatataa aagaaaaaga taaataatca gattcattaa
     4381 tttgtataaa ctattatttg tttgaaattt cataaacccg tccttcctct attaaaatcc
     4441 tttgagattt gctaatcaat tcttgattca ataaattatg agatacatat ataatagtag
     4501 agctttcttt catggaaatt aagcgtttag caatcatatc aatacttctt gcatccactg
     4561 ttgataaagt ctcatcaata aaaatataat cccaattttt agcaaaaatt aaggataagc
     4621 ctaatttgaa ttttgttcca gtagatgctg tcatatagtt atctccgatt ttattatcaa
     4681 aaaaagtatt aatttgttct ttatcctcaa atgatagatg gatttgaaaa gaatcacaca
     4741 acaactgcaa attttcttct atagtaaatg gaacaacccc aagctgattg gtatcaaggt
     4801 atagtacatc tttggagaca caattcttta aaccactatc aaaagtctct agcccagcta
     4861 aaagttgtag aagggtgctc tttcctgaac cattctctcc ttcaactctg taaattccct
     4921 tatcaatctc tagtgatata tttttcaata tacatttatc ataactttta gattcatttt
     4981 caattttcat aatttaattc cctctatcaa cgctgctaaa attaataaaa gataagaaat
     5041 gatataccat tttaaattac tttttatata aataagtata tttttaattc ccctatcctt
     5101 caataatcgg tataaaagat actgactcat accttgatac caaataaaat tcggtatttc
     5161 aataagagca tgaggtaata ttccttttat tgtagctact attccaatca tctgaccaga
     5221 tatacccaat tgtattccta aagatagcaa atcaaaaagt tgcaataagg gcgaaatcgg
     5281 aaaacagaat agatatagca aaaaatttgt agaatttgcc tgtaaaactg tcaatgtaaa
     5341 ttgtaattcc agtttcggag gtatagtagc aaaagtctca ttttttaata taaagcttaa
     5401 aagtaaacct agtaaaaaac agactataca aaataacaca tagtaaatca gaaaaccact
     5461 ttttctcatc taatgccccc tactaaaatt acaaatatta tcagaaaaca atataaaacc
     5521 agaaaactcc atctcaataa actaactgta cctttaatta aaaatagagc tttcttataa
     5581 tagacatagg ctataaaata attgaatgga atcaataaca aattcaacaa aatacttttt
     5641 atatcattac tataacttgt caccggaatc aaacataaca acaatgaaaa ttgtaagaaa
     5701 gagattaaat gcgtcaacat cattagttgt gcattcttaa aaaagaaatt cattttagaa
     5761 tgattaagag cagataattg aagtaaagct agatctaccc caattgagga tttatgattc
     5821 cctattattg cctccattaa tgtaatatat attgaggtat aaagaaataa tattggtatt
     5881 tttgtgtcat caattgataa catcgtcatc atataccaaa atagatagga aagaagaata
     5941 ctaatcaaaa taaaagaaaa agttaaccct ttatttaacc aacaaaaacg aagcaatata
     6001 aatagactgc tacgaaatct tttttgactc attcgactgc ttttaaaata gaaattactc
     6061 gcatgattat ctaatatccc catgactaaa ataaaataat tgagtagtat gacataaatt
     6121 acaacttgtc cttgttctat agacaatagt cctatagata aaaataagaa caatttactt
     6181 ataattgaaa acaaactagg tagaattaaa gaaataattt gaatagctat caaacaaaga
     6241 gtaatggata aataaaaata tccaataata tctagaaaat acaaaataaa taaataaatg
     6301 aatgattgta aaatttggaa agaataatat ttcttgacaa tggcaagaag atagagaaaa
     6361 atatagtttt tccttatata gaaagtattt atttttttac tttggatagg cagtttcata
     6421 ttataacgat tcaaagtagc gtaatctact accaaaaaaa gtaaaaataa tttcccttga
     6481 aaaggaagat agcttttaaa atagattgac aaacttatga taacaaaaaa caaaagggtt
     6541 atcccaataa aattaagata acctaaaata ctttcacatt cttttttaga aagtattttc
     6601 atctagttct accatagagc tgctttagca gcacctttct ttttcaatat ataaagaact
     6661 gttgctgcaa tacccgaacc aatagaacct actcctgtga ttgcacctac aattgaaatt
     6721 actgctgtaa ctgtactata agcactaatc aaattgacta cagtagcagc agcttttgtc
     6781 gaaattccta atgtcccagc caacatagga aaagaaacaa cacctaagct taaccaacta
     6841 atgactgcta acattgctga aacaataaga aatttattat gaaattccat tcttttagat
     6901 ttcattttag tgtactcctt ttgtatatta tgtatgtttt attgagagtt aattcgcaca
     6961 tgttgtattc ctaactctct tcaaatgttc gtctatattt tatactactt ttattaacat
     7021 atctataata aataaattac tactacattt tcctagatta tcaaattact tttatatcac
     7081 taagactcaa taaaagataa tgtctattta acttttatac gattactacc tctttttagt
     7141 ttacacttcc tacatcataa ataaacatac tcaaccctca caatctccaa ataactcttc
     7201 tatatcattg aaaattgagt ttcatcctct atactaatgt aggacattcc tttaatccaa
     7261 tataagaata ccttgttcca ttaatctcta cccgatatta tagatagaac caaattccta
     7321 tacttaaaag gacaaataac gttccaacca taataaacct cctttctttt tgagaacgtt
     7381 ttctttatag gtttagtata gcaaaaacat gaaaaaaaca acatgactta gaagtcaggt
     7441 tgttgggaaa tctatctgtt tttctgctaa aattctctga actaatacct gatcgtctag
     7501 caattctgct agagaaatcg ccttttcata gaaactttct gcctctaaaa tattcttgtc
     7561 tacaaataaa gcatattttg cctttagcaa aaatagatga ggtcggtaaa aaacatgtct
     7621 tgttttagca ataattttct caaatgtttg aatatatatc agactatctt ctgtctgaat
     7681 ttggataaat aggctcagaa gaactttttc catttgaact aggctagcct tatcttcata
     7741 ttctgaacat agcaatactt tttgagctaa ctcctcaaaa tgttctttat cttctaatcc
     7801 catagcacaa caaaagaaat acaattcaat aatcaacaaa tcatttacag aaaaatattt
     7861 cttttttaat aactgctgga aatattcttc cactaaccct aaaccgtagg tcacatctga
     7921 actaccataa atatcaaaac gagcttgtgt cacatccaca attaactgct cttcctcagg
     7981 caaattctca taatagtttt catatatttc ctcaagtata gcttcttttc gttcgattct
     8041 tcccttatca gcgtaggttt gagaatgaat cagctcatct ttgagtttta ggaatccttt
     8101 tggaatctct ataaccttaa catccacaat attctgtaat gatactccaa gtttatccgc
     8161 aatcaataat aatttaggaa gtgttgctaa agcttgccca ttttcaatac gtgctagctg
     8221 acgaatcgtc aactctgatt catcaccaca aatatctatc tgagtttttc cacaagatcg
     8281 cctaatagtt ttgattttat aaccaatttc acgtttcaac tcatccatag taatactcct
     8341 taagttgatt acaaagattt ctttttcttc ctaattcttt tgtcaatcat atataaaacg
     8401 ataagcgaaa acagcggtag aacaatataa ctcttttcac tcattatcag ctgaaatccc
     8461 agggttgcta gtatcttaaa gatgaaaata ttcatcaaaa atagaaaaac aaatactaaa
     8521 aaatatttta aaaccttctt catttctttt cttcaacttt cctaatttct acacctattt
     8581 tatcgaaaat atatataaaa ctccaaataa acacttcgac tgcacttttt ttggcaaaaa
     8641 atagacagaa caaacatcct acctactaaa aatatgatat gaaaggaaaa tgatttttta
     8701 ctgacaccct aggcaagctt gggacaaata aatcattgat agcaacattt acgacatcct
     8761 atttaaagtt ccttcaattt ctaatgtccc cgctatttct aagccacctc tggtatgatc
     8821 tattcctagt cagaatagat aacaccgttc taaattacga ttcatagtta ctcctttttt
     8881 gactcgttac tataagactc ctatttacat gcgcaaaata attttgattc agattcatca
     8941 tttatagttt tgattatttt ttaacagatt tttctgtttt cttctccgaa gactttaaaa
     9001 atttttttct aattaaatca tccatataag gaccaaatat accaactact aaaccaataa
     9061 taaaactttt aaaatccata attaccacca acatgtcgct gcataggcca cacctccaag
     9121 tatagctcct cccacagcac cagttgctgc accttgccat gttcttgttt taattcctag
     9181 ctgaagacct cgtactgctc ctcctccaac acctgctttg gcaaaatctc cccaattgca
     9241 tccgccacct tcaacgcaag caagcatctc agtatccata atttcaaatt gtgacatctt
     9301 ttttgtattc ataacgaata cctctttttt atttttaata tttgtcttgt tacaaacttg
     9361 acaagtttag tataacagta tctattaatt tttttcatcc aaatcttgaa ttggcatcga
     9421 aacgtcttga attagctttt ttgtttcaaa atcatctcta tttttaaaaa agatgttttc
     9481 taatcacttt tttactatta gacttcctgc aaaactagaa tcctagttca tgattgataa
     9541 taccagcaat caaattcatt cgtaatccga agcgtttacg atgatttcga taggttgttg
     9601 aaaacatttt aaacgttttt actttggcaa agatattctc aaccttgctt ctctccttag
     9661 atagcgcatg attacaggct ttatcttcaa ctgttagcgg cttgagtttg cttgatttac
     9721 gtggagtttg tgcttgagga tatatcttca tgagcccttg ataaccactg tcagccaaga
     9781 tttttccagc ttgtccgata tttctcattt ctaaaaacca tctacttccg ttgacttgga
     9841 actccgattg ctattttcct tgaatgattt taaccacatc tcctacgttt tggagttggt
     9901 caatttcttc atcgctgatt tcgatactaa attcatcttc cagagtcaag ataaactcca
     9961 tcaagtcaac agaatccgca tccaaatcgt ctttcagact caaggattct gtcacgacaa
    10021 agtcctctcc ctgtcgctct tggataatgg tcacaatacg gtcaaaaatt tctttttctg
    10081 tcatctcttt tattctcctg aaaattcacg cgcagtctgg gcaaccacgt ctgtttctag
    10141 catggtacgg atctgacgaa tcgtactata aacagccttg gcatcgcttg agccatgagt
    10201 cttgacaaca ggtgccttaa caccaaacaa gaccgctcca ccaacatctg aataattgag
    10261 ctgttttttc aaacctctga ggctgtcctt gagaaggagg gcacctagtt tcgctcgaag
    10321 accaccacct gtaatagctg tcttgagcaa gcccatgatt cccatagctg tcccttcgat
    10381 ggatttgagc acagcgtttc ccgtgaaacc atctgccaca acaacatctg caacgccatt
    10441 catcaaatca cgcgcttcca cgtttccgat aaagttcaaa ctttcatcag ccgccagtaa
    10501 ttcataagtt tccttacgaa gcgggtcgcc cttgctactc tctgttccgt tgttgagcaa
    10561 accaacgcgt ggttgcgcaa tgccacggac atttttagca tagaaggaac ctagaaccgc
    10621 atattgatgg aggtgctggg ctgtattttc tgcattggca ccaaggtcta gcatgtcaaa
    10681 accttttcca tcaacggtag gcaaggtaga catgagtcca ggacggtcga tattcttgat
    10741 acgacccacg acgaagaatc ctgctgccaa caaggcacct gtattcccag ccgaaaggac
    10801 agcgtctgct tcaccatctt tgacagcctt ggctgccaat accatactgg catttttctt
    10861 attcctaata gctctcgtag gttcatcatc cgaatcaatc ttctcatccg tatggataat
    10921 gctgacgcgc tctgtcgctg tcagatattg cttgatttta gcttcatctc cgtaaagttg
    10981 aacctcgata tctgaaaagt cagatagggc ttgattgaca ccctcaacaa tggcctgagg
    11041 tgcgtaatcg ccccccatgg catctactgc gatttttttc atttcttttc ctcttttagt
    11101 aattgtcccc agtctgctag ggaatcaata aatttctttg attttaggtg aatcccaacg
    11161 tactcttcat ataattgatc cataaattgg cgtaactctt gcttgattcc aggcttgagc
    11221 gaaatggtct ccaaagtctc aaaatcaata gcttgaaatt gattgagcag ataggggata
    11281 ttgggattga gatgacaacg tctcttatcc tcatgataat gctctggaca gaggcaggct
    11341 ccatatttga aagaaaagtc aaaagcctga ccaacccgat ggcagaagac acactcatta
    11401 aaattgaggc tgattccaaa tcgagtcaaa atttgaattt caaaaatatt ggtcaaaacc
    11461 tgataatcca agcctgcttc catcaactcc aaagtctttt gcaaaaaagc aaacaaggga
    11521 gcatcctgct gattgtcctg caaactagca tctgcaagag ctgccacata ggtcgcatag
    11581 gccatgacaa agaggtcact attaatcttg ggaaaagtca tgacctcatg atagtcttcg
    11641 atgtaactga gtccgtcatc attgattcgc aagagaaatc gtgccagcac caagggctga
    11701 ataacaggcg ccagcttaga ctgaccagcg tgtttgacaa aaaacatgcg tttgccaacc
    11761 tgctctgtaa aaattttgac gagcttgtca tcctcacgaa aattgcgatt gtaaagcacc
    11821 aagccttgac tcgtgataga ctgaatcatg cttctctcat gtactcctca agtcgtttca
    11881 tggcttcttt gatagtctcc atgctggctg cataagatag gcggacgtag ccttccccgt
    11941 aacgtccaaa ggctgcacca gggataaagg caacggcctt cttctgagca aaatccttca
    12001 gaaaagcaaa ggagtcttga ttgtagcccg ctggaatttt agcaaaaata tagaaggcac
    12061 cgtctggttt gataatctca aaaccaagag cagtcatttt ttcgatgata tagtcccgac
    12121 gctggatata ttccttcttc atgggctccg catcattttt accagccgtc aaggcttcta
    12181 ccgcagcatg ttgcgccatg gtatttgcgg cagtgaccaa gtactggtga ctcttgatta
    12241 actgggctgt gaaggtcgca ggagcgaaaa tcagccccaa acgccaacct gtcatggcat
    12301 gcgatttaga caaaccattg ataataatag cctggtctct caacatcgtt cctagagaca
    12361 catgggcttc gcctgtgtag gtcaattctg agtaaacctc atcacagaca acaaaaactt
    12421 cgtacttgcg taaaacagct gccaaggcct ctaactgctc tcgactgtag gtaattcctg
    12481 tcggattggc tggatagttg agaataaccg ccttgagctt atcaccctgc tccaaaatgg
    12541 ccttctccaa catctcagga gtcaagacaa aaccattttc agtcgtatca atctcaacaa
    12601 tttctgcccc aactaagtta acaatcggtt cataacccgg ataagcagga gctggcaaaa
    12661 gtaccttgtc tccctcttcc aaaatagccg tcaaagtcgc agataaagcc tctgtcgccc
    12721 caattgtaac caagatttca ttttcaggag catagtccag ttggtacttt tccttaacaa
    12781 agtcactggc tgcctgacgt agagtcagca gaccactcat ccctgtatag taggattggt
    12841 tctgatcaat cgctcgcttg gccgcctcct tgacatggtc tggcgttgta aaatcaggtt
    12901 cccccaaggt caaacgcaag accccaggaa tctccgaaat aacctggtca aactgacgaa
    12961 tcaacgaaac ttgaatttta tctaactgtt tattaaagcg cttagttaag tccatagata
    13021 cctcctactt tcaaaacgta tctctattat actacaaaag ccccccgacc gcaaaaatac
    13081 attagagaat agctttccac tttctatttt acttttcctg tttataggtc tataatggta
    13141 acagattcta tttggaggtt tttatgtcat ttctatcaaa aaatggagca ggtatcttgg
    13201 cctgccttct catttccatc ctatcttggt acttaggagg attcttccct gtgattggcg
    13261 cgcccgtttt tgccattttc ataggcatgc tcctacatcc ctttctctcg tcctataaac
    13321 aactggatgc tggtttgacc tttagttcca agaagttgct ccaatatgcc gttgtcttgc
    13381 ttggttttgg tctcaatatc tcgcaggtct tcgcagttgg ccaatcttca ctccctgtca
    13441 tcctgtccac tatctcaata gctctgatta ttgcctacct cttccagcgt ttctttgcac
    13501 tggatacaaa actggctacc ttggttggag taggttcttc tatctgtggg ggttctgcca
    13561 ttgcagcgac agcgcctgtt atccatgcta aggaaaagga agtagcccaa gccatttccg
    13621 ttatcttttt cttcaatgtc ttggctgcgc tcatctttcc aaccctcggc acctggcttc
    13681 atctatccaa tgaaggcttc gccctctttg cagggactgc ggtcaacgac acttcctctg
    13741 taacggctgc cgccagcgct tgggacagtc tttaccaaag caataccctc gagtctgcaa
    13801 ccattgttaa actcacacgt actttggcca ttatccctat cacgctcttt ctatcctact
    13861 ggcaaagtcg ccaacaagaa aacaagcaaa gcctacaact gaaaaaagtc ttcccacttt
    13921 ttatccttta ctttatcctt gcctctctcc tcactacact actcacctct ctaggtgtgt
    13981 ccagtagttt ctttacccct ctcaaacaac tctctaaatt ccttattgtc atggccatga
    14041 gtgctatcgg tctcaaaacc aatctggtcg ctatggtcaa atccagtgga aaatccattc
    14101 ttcttggagc catctgctgg attgccatca tcctcaccac tcttggtatg cagaccctta
    14161 tcggcatttt ctaacactct tcgaaaatct cttcaaacca cgtcaacgtc gccttgccgt
    14221 atatatgtta ctgacttcgt cagttctatc tgcaacctca aaacggtgtt ttgagcagcc
    14281 cgcggctagt ttcctagttt gctagtgtgc tctttgattt tcattgagta taacacaaaa
    14341 ggtagcccat cagctacctt tttcttatgc ttcctcaatc aagcgagtat gttctctctt
    14401 gatacagcga ttcatcacga tatcatcaca tccaccatca cgcaaaatct ctttcgcttc
    14461 taaactttca agtcctagct gtgcccaaaa aatcttggca tcagctttga gaaaatcacg
    14521 cgccacatcg ggcagaaatt cactgcgacg ataaacattg acaatatcta caggaaaagg
    14581 aatttcagcg aggctagcat aagccttttc acccaagatt tcgccacctg ccgccttggg
    14641 attgactggg atgattttat agccccgagc ctgcatttcc tttgttactc gattgctggt
    14701 tgtttcttca cggtcagaca aacccaccac agcaagggtt ttactcgttg cgagatactg
    14761 acgaatcaca ccatcacttg gattgataaa ttcttgactc atagaaaacc tcctttttca
    14821 tcagtatagc acattttgaa aaggtttgca gaattctact acaaaaaagg aggactagcc
    14881 ccctttttat ttagcctcgt accaggttgc cccttcattc tcatctgcga taagaggaac
    14941 actgagttga atggcttctt ccatggtttg tttcaccaat ttttttatct ctaccaattc
    15001 agatttaggc acttcaagga cgatttcatc gtgcacttgt aacagcatct tagtctgata
    15061 accacctgca accaaggctt tatccagctg aatcatggca atcttgagaa tatctgctgc
    15121 cgaaccctgg ataggtgagt tgatagcagt tcgctccgca aaaccacgaa tattgaagtt
    15181 gcgcgaattg atatctggca actcacggcg acgcttaaag agggtctcta catagccctt
    15241 atcacgcgcc tcccgcacca cttcatccat gtagttttta atacctggaa aacgttcaaa
    15301 gtaggtatca atgtaggctt tggcttcctt acgactaatt cccaaattat tagacaagcc
    15361 aaagtctgaa atcccataaa ccactccaaa gttaactgcc ttggcattgc gacggtcatt
    15421 tgcagtcaca ttatcaggac gctcaatgcc aaagacccgc atggctgtcg aagtatggat
    15481 atctgccccc tcttggaagg ccttaatcaa gtgctcatcc ttagaaatat gcgccaaaac
    15541 gcgcaattca atctgtgaat agtcagagct gagtagcaca ctatcctccc actctggcac
    15601 aaaagccttc cgaatcaagc gcccttgttc caatcgggca ggaatatttt gcaagtttgg
    15661 atccacacta gacaaacgcc cggtctgggt caaatcctgc acatagcgag tatgaatctt
    15721 tccatcagcc aaaatccagt cctgcaagcc aattacataa gtagattgaa tcttagcaat
    15781 ttgacggtaa tccaggattt tcttaacaat cggagcaata ggagcgagac gctccaaaac
    15841 atccactgct gtcgaataac ctgtcttggt tttcttagtg tattctagag gaagtcccaa
    15901 tttctcaaag agaagcacgc ccaactgctt aggcgagttg acattaaact cctcaccggc
    15961 cagctcgtaa atctcttgag tcagtttttc aatgacaagc tcattttcag cctgcatctc
    16021 aagcaaggtc tctttcttga ccataatccc agcaatttcc atcttggcaa ggacaaaagc
    16081 cagaggttgc tccatatcat aaagaagctc taattgccca ttttcgctga gtttttcaag
    16141 taaaataggc tctgtttcta ccaaaacagc aagtttacaa gctaagtgtt ccaagaattt
    16201 ctcacgttca ggaatggcct ttttaacacc cttaccgtag aaagtttcat catcaaccaa
    16261 gtaagtctga ccataaagac tagcgatggt cgcaatttca ttgtcctcca cagtcgaaag
    16321 gaggtattta gccaaacgga tgtcaaaagc aggcgcctgc aaatctacac caaaacgttg
    16381 caaaagaact ttaaccttct taaagtcata aactctcaga gatgtttttt ctaagaaatc
    16441 cttgaaaatc gggtcttgca acagctcaag cttgtctgtg gcatagagct gatccccaca
    16501 agaccaggca aatccaacca aattatctgt atggtaattc tcaccaaaaa gctcaaagtg
    16561 gaagatagac tcttcactca gcatatcttg actgatttgg tcaacaatag taaaatccaa
    16621 accctcagcc acatcagctg acgacacatt taaagcctgc ttgagctgtt tgaagcccat
    16681 ctcatcgtaa aatttcccaa gattttcaac atctggacca ctatagacca agtcctctaa
    16741 accaatcgca atcggtgcct tggtatcaat ggtcgctagt gttttagaca aaaaggcctg
    16801 ttccttgtca ttgatgagat tttccttcat cttagaagtc ttcattccat caatattttc
    16861 ataaatcccc tcaagcgaac catgctccag caagagctta atacccgtct tttcaccgac
    16921 tttggtcacc ccagggatat tatccgactt atcacccatg agcgccttga gatcgataaa
    16981 ctgagctggt gtgaggccca tttcttccat gaggtaatct ggcgtaaagg cctcaaactc
    17041 agccacacct ttcttggaaa tttcaaccac cgtatgctca tccgtcagct gaatcaaatc
    17101 cttgtcccca ctgacaatgg taatatcaaa accatcctgc tctgctagct tatccagcgt
    17161 cccaatgatg tcatccgcct catactgagc cagctcatag tgacgaatcc ccatctgatc
    17221 cagcaactca cgaatgaaag gaaattgctc acgaaactca tcaggagtct tggcccgacc
    17281 acccttatag tccgcataca tctctgtccg gaaggtcgtc tttcccgcat caaaagccac
    17341 caaaatatga ctcggctcaa cccgctccaa caaatgactc aacatcaact gaaaaccata
    17401 aatcgcattg gtatgcaaac cagccgcatt cttaaaacgg tccaactgct gatacagcgc
    17461 aaaaaacgcc cgaaaagcta cagaagaccc atcaatcaat aataattttt tcttatccat
    17521 acacccatta taaaggaaag aatcaaaaaa taccattggg aagagctaga gcaagtattt
    17581 ttcaaacttt ttccgaataa atagatagag ccagagaatt tagtaaacct agatttaaaa
    17641 atgtgctata atatagtata ttgaatctat aatagtacac cttgactgct aaaatatttc
    17701 tataaattaa tttgactttc ctgatagagt tattcacatc ttatttcaac tcactataga
    17761 aggaggaata ggaggattct cagacatccg ggcatcagcc caactaatga tttgattgct
    17821 aagaaaatat tcagcaatcc agaaatcact tgtcaattta ttcgcgatat gctggacttg
    17881 ccagcaaaaa atgtgaccat tttggaggga agcgatattc acgtattact ctccatgcct
    17941 tactcggtgc aggattttta taccagtata gacgtcttgg cggagttgga taacggtact
    18001 caagtaatta ttgagattca agtccatcat cagaattttt tcatcaatca cttgtgggct
    18061 tacctgtgca gtcaggttaa tcaaaatctt gaaaaaattc gtcagcgaga agatgatact
    18121 cactagatct acaaacacat cgctcctgtt tacgtcattg ctatcgtgga tagtaattat
    18181 ttctcagatg acctggcttt tcatagcttt agtatgcgcg aagacacaac aggtgaggta
    18241 ttggcgatta ccaacaatgg acaggaaaac catctggtta agatggcatt cttggaatta
    18301 aaaaatacag agaaaccagc aaagacaagg ttcgcaagcc atggttggag tttttcggca
    18361 acaagccctt tacccagcaa ccgcaacgag ccattaccca agcaaatcaa ctgctggact
    18421 acaagagctg gtccgaggag gacaggaaaa tgtttagtca actacatatg cgagaagaac
    18481 aagtcttgtt agcacaggac tatgccttgg aaactgctag ggctgaaggc cttgaacaag
    18541 gactagagcg tgggaaagtt gaaggaaggg cagaaaggaa actttttgcc ttcctagaca
    18601 tagtacgcca aggtcttctg gcttctgagg ttgccagcca gcaattaggt atgtcagtat
    18661 ctgaatttga ggcactgttg taaaatggct ccataatatc cataggggat ttacccacta
    18721 tggatattat ggagcctatt ttgtgta
//
LOCUS       DAVEHY010000045        18666 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVEHY010000045 DAVEHY010000000
VERSION     DAVEHY010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18666
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.045"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(115..390)
                     /locus_tag="VUZ44_001872"
     CDS             complement(115..390)
                     /locus_tag="VUZ44_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU0320736.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(496..1335)
                     /locus_tag="VUZ44_001873"
     CDS             complement(496..1335)
                     /locus_tag="VUZ44_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU0320737.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1477..2325
                     /locus_tag="VUZ44_001874"
     CDS             1477..2325
                     /locus_tag="VUZ44_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU0320738.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2418..3335)
                     /locus_tag="VUZ44_001875"
     CDS             complement(2418..3335)
                     /locus_tag="VUZ44_001875"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU0320739.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3773..3978
                     /locus_tag="VUZ44_001876"
                     /pseudo
     CDS             3773..3978
                     /locus_tag="VUZ44_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4289..4582)
                     /gene="rpmA"
                     /locus_tag="VUZ44_001877"
     CDS             complement(4289..4582)
                     /gene="rpmA"
                     /locus_tag="VUZ44_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU0320740.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4599..4943)
                     /locus_tag="VUZ44_001878"
     CDS             complement(4599..4943)
                     /locus_tag="VUZ44_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU0320741.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4959..5273)
                     /gene="rplU"
                     /locus_tag="VUZ44_001879"
     CDS             complement(4959..5273)
                     /gene="rplU"
                     /locus_tag="VUZ44_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU0320742.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5309..5396)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5461..6159)
                     /locus_tag="VUZ44_001880"
     CDS             complement(5461..6159)
                     /locus_tag="VUZ44_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU0320743.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6561..6860
                     /locus_tag="VUZ44_001881"
     CDS             6561..6860
                     /locus_tag="VUZ44_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU0320744.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(7202..8176)
                     /gene="pta"
                     /locus_tag="VUZ44_001882"
     CDS             complement(7202..8176)
                     /gene="pta"
                     /locus_tag="VUZ44_001882"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU0320745.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(8220..9116)
                     /locus_tag="VUZ44_001883"
     CDS             complement(8220..9116)
                     /locus_tag="VUZ44_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU0320746.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(9113..9931)
                     /locus_tag="VUZ44_001884"
     CDS             complement(9113..9931)
                     /locus_tag="VUZ44_001884"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU0320747.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(9915..10586)
                     /locus_tag="VUZ44_001885"
     CDS             complement(9915..10586)
                     /locus_tag="VUZ44_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU0320748.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            10714..11283
                     /locus_tag="VUZ44_001886"
     CDS             10714..11283
                     /locus_tag="VUZ44_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU0320749.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQLTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            11396..12355
                     /locus_tag="VUZ44_001887"
     CDS             11396..12355
                     /locus_tag="VUZ44_001887"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU0320750.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            12365..13480
                     /locus_tag="VUZ44_001888"
     CDS             12365..13480
                     /locus_tag="VUZ44_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU0320751.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEANNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            13485..13832
                     /locus_tag="VUZ44_001889"
     CDS             13485..13832
                     /locus_tag="VUZ44_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU0320752.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            13840..14055
                     /locus_tag="VUZ44_001890"
     CDS             13840..14055
                     /locus_tag="VUZ44_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU0320753.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            14138..14779
                     /locus_tag="VUZ44_001891"
     CDS             14138..14779
                     /locus_tag="VUZ44_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU0320754.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGRALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            14797..15486
                     /locus_tag="VUZ44_001892"
     CDS             14797..15486
                     /locus_tag="VUZ44_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU0320755.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(15483..16163)
                     /gene="radC"
                     /locus_tag="VUZ44_001893"
     CDS             complement(15483..16163)
                     /gene="radC"
                     /locus_tag="VUZ44_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU0320756.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(16206..18497)
                     /gene="pcrA"
                     /locus_tag="VUZ44_001894"
     CDS             complement(16206..18497)
                     /gene="pcrA"
                     /locus_tag="VUZ44_001894"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU0320757.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESRARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
BASE COUNT         5716 a         3937 c         3416 g         5597 t
ORIGIN      
        1 tacaatattt tcggaacatt caacttttta actctattta ttactagatt tcataattaa
       61 aaagcctact gaccaagcta gaaagcttga tacaataggc tttttaaaga ctgattattt
      121 aacagcgtct ttaagagctt taccagcttt gaatgctggt actttagaag ctgcaattgt
      181 catttcttta ccagtttgtg ggttgcgacc tttacgttct gcacgctcac gaacttcaaa
      241 gttaccaaaa ccgatcaatt gaactttttc accagctgca agatagtcag ctactgctgc
      301 aaatacagct tcaactgctg ctgctgagtc tttcttagtc aattctgtag cttctgctac
      361 tttagcgatc aaatcttgtt tgtttgccat gttaatgatt cctccagata atttctaatt
      421 aacaaatata atcatatcct aaaatccctt ttaggtcaag ttaaaaacgc tatttcttcc
      481 aattttattt attttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt
      541 gtgagtttga ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg
      601 taagctttct ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc
      661 tgctacagca cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt
      721 agttccacga cctttaacca ttggctgcaa ttcatggtct ttcatttgca tgacaacacg
      781 gatattgaga agggagctca acaagccagt tacacggcca attcgtccac ctttgacaag
      841 attttccaaa gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg
      901 agataaaatt gcctccatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg
      961 gaatttcagg gcttggtcag tgaaggaact atcaacaaca atcacatctg cagtagatag
     1021 gctagcacct tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc
     1081 aagaatctgg ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg
     1141 tggctgactt gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc
     1201 ttctttcaaa tccgcatcag aataaacaac attatcaatc attacagata atggaacaat
     1261 tgtaatatct aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat
     1321 cttaattttt gtcatagtat caatctttct attttaggat tcagattggt ttccttactt
     1381 ttaattatat caaaaaaaag attaaaaatc ctaatggagt caatcaaatt ttccgtaaaa
     1441 tttgatataa tcaacttata agaaaagagg tgtcctatga ttaaaaaaat ttaccccatt
     1501 tttaccattt tactaggtgc tgctatttat gcttttggac tgacttattt tgtagttccc
     1561 catcatctct ttgaaggagg ggcgacaggc attaccctca tcacctttta tctttttaaa
     1621 atccctgttt ccctcatgaa cctgctgatt aatattcccc ttttcatcct agcttggaag
     1681 atctttggag ccaaatccct ctattctagt ttactaggaa ccttagcttt gtccgcctgg
     1741 ttagcttttt ttgagcatat tccccttcat attgatcttc aaggtgattt actaatcaca
     1801 gcccttatag cgggaatcct attgggaatt ggccttggaa ttatttttaa tgctggaggt
     1861 acaactggcg gaactgatat tctagctcgt attctcaaca aatacactca tatatccata
     1921 ggaaaactgc tctttatctt agatttttgt attctcatgt tgattctcct aatcttcaag
     1981 gatttgagat tggtttccta cacgcttttg tttgatttta ttgtttctcg tgttattgat
     2041 ttgattggtg aaggaggata tgccggcaaa ggctttatga ttatcacaaa acgtcctgac
     2101 caacttgcta aggcgattaa tgatgacctc ggaagaggtg ttacttttat ttctggtcaa
     2161 ggctactata gtaaagaaaa tttgaaaatc atctactgta ttgtcggaag aaatgaaatt
     2221 gtgaaaacga aggaaatgat tcatcgaatc gatcctcaag cctttataac tattacagaa
     2281 gcccatgaaa tcctaggaga aggcttcacc tttgaaaaag aataaaaaga ggtaatgtcg
     2341 tgacctcaaa agttagacta aatcatctat cttttgggtt acagacaacc tcttttttgt
     2401 tttatttact caagctctta agaccaattc cgagttactt cttcatcagc ctttaactga
     2461 tccactaatt ggtcaactga gtcaaatttg gtcatatcac gaatgcgatc aagccaataa
     2521 accatgacgg tttccccata aatatcttga ttaaaatcaa aaatattgac ttcaaaacgt
     2581 gcttcttctc catcaaaggt cacatttttc ccgacactag ccatagcacg atacttctgt
     2641 ctttgaatct caacatcaac gacataaacg ccatctgctg gcatataagt acggtctaaa
     2701 agcactaaat tcgctgtcgg ataaccaatt gtacgaccac gagcattacc atgaactacc
     2761 atacctcttg atggaagcgg tgcccccaaa agttttcctg cttctttcac atttccatct
     2821 aaaatagctt gacggatacg agttgaacta atctttcctt tctcatcttc tacaggtgga
     2881 acaatgataa cttctccatc aaagtaatcc tttaaatctt ctgctgtttt tttgtcagaa
     2941 ccaaatgtat aatcaaaacc tgcaacaata attttggcat tcatagcctt gatataagtt
     3001 gcaaagaatt cttgtgcagt gagactagcg aattgactac taaaatcaag gagatataat
     3061 tcttctacac cttcgcgctt taattttctt tcacgttcag cagggttcaa aatatgcaaa
     3121 aacaaatctg gatgataagg ctctaaagcg atctttggag attcattaaa ggtcataacg
     3181 acgataggca ataaatcctt tctcgcagcc ttgttggcaa cacgaaataa ttcttgatgc
     3241 cccttatgta tgccatcaaa atagccgaga acaacgactg aatcagatgg tgtgccaata
     3301 tctttttggt tttttatagg aatagtaata atcataaaat aattatatca tagcgatagc
     3361 tatttctgga acagaaaatc tgaaatgttg tttttttcac atgaagtgta cctgttttca
     3421 aaaagcactt tattctatcg ttgcttaact atgaactttg caatattctt ctcaaaaact
     3481 tgtaggacat cttcaaaatt ttgcaaggag tgattagact tgttcggtaa ctataaagtg
     3541 tcatactatg cttatgtatg aaaaagcaat gcaactaact cctgagaact ttaaattact
     3601 aattggtgcc gaaaaggtag aatttagaat agaggtacac ctatggctgt aaaatttaca
     3661 aaatgagaca acttgggcaa gatgtttgaa gaatttccta aactccctga tttgaagcaa
     3721 gtcactttcc ctgatgacaa agaaaaaagc caaagcaata aagaaaaact agatgactgc
     3781 tttccaacaa ctcccatcta gtgtgcttca gactgggcta tttttctctc catctgttag
     3841 cttggattct cagaccgttt cagctaaaga atatcttttc ctttatcaga aggaacggct
     3901 caagccattc agacaagtga agggacgaca agccaatatt tgaaaccaga tagcagttct
     3961 tatagtcaat tgaaataaaa tctgaagaaa tcgagtagga aactcaaatc aatttttagc
     4021 agtgttctat tccagattca tactcaatga aaattaaagt gcaaactagg aagttagccg
     4081 caggctgtac ttgagtacgg caaggtgaaa ctgacgtggt ttgaatttga ttttcgaaga
     4141 gtatcaatcc actatacata ttaaaaagta tgggtatcaa aataaaaaaa caggctctcc
     4201 gaaaactcag aaagccttat tttaagctgt ttctagtttc ctcaccttta catttcaagg
     4261 ttcgggataa aaggttcaat ggaccttttt atttagcgat tgggtaaaca gaaacttgtt
     4321 ttttatcgcg tcctttacgt tcaaagcgta ctacgccttc aactttagcg aacaaagtat
     4381 cgtctccacc acgaccaacg tttacacctg gatagatgtg tgtaccacgt tgacggtaaa
     4441 ggattgatcc acctgttaca gtttgtccgt cagctgcttt agctccaaga cgttttgctt
     4501 gtgaatcacg tccgtttgat gtagaacctc cacctttttt gtgggcgaaa agttgcaagt
     4561 tgttaagagt catttttaac ataatgtttt cctccgtgtt agttttctgt gataactctg
     4621 gtttggacga actcagaaga gttctccgat aagtttgcca tacctaagaa aaatgattca
     4681 aagaataact gggtcatttc tctctggtgt gaaggaagat cttttggtat ttcaaccatc
     4741 agatagccac cttcatcttc gtttaattct aggattggtt catagcctgc aaatttctca
     4801 atagaattga taaagttaat ggcaagcgta gaaaccgatg cacacacgac atctaagccg
     4861 tattcgccac tctcggcgtg tccagtaatt tccgcactcc tcagctcgcc atcttcggct
     4921 ctctcaaaga ctgcctgtat catgtgttct ccttaaaatt aagcgttgat tgcgttgatg
     4981 acaacttttg tatatggttg acggtgacct tgtttacggt ggctaccttt tttaggtttg
     5041 tacttgtaag taaccacttt cttttgtttt ccttgttttt caacagttcc aactacagta
     5101 gctccagcaa caagtggagt tccgacaaca gtgttttcac caccaacaag aacaacttcg
     5161 ttaaaagtaa cttcttgacc agcttcaacg ttcaattttt caacgtaaac tgcttgacca
     5221 acttcaactt taacttgttt tccgccagtt ttgataattg cgtatgtgct cattatgcac
     5281 ctcctatgat ttttatgggt ttccccgatt ttttgtgaag actcgcctag catcgtggga
     5341 cgaaccactt aaacttgaat aatcaagcaa cgatgttcgt gcggttgcac aggatcgtgc
     5401 atagtcaact cttcaagtat agcatatctc ctattttctt acaagtaata acacctaaaa
     5461 tcaagctttt tcttttactt ttttctgcca agaggcaaaa agcatgctga ggtaaaaaac
     5521 gctcatcata ataggaacac caagaatggt cttttcatga tagaaaatcg tcaaataggc
     5581 tgaaaagaca acgccaagga caaaactact aagcaggcta acaaatatga atccttcacg
     5641 caaaaaagga gtgtgcttgg ttcggaaata atctccaaaa gccagcatgg tccgtttgat
     5701 attccctgtc ataaaagcgt tattataggc aatacccgac acttctccaa aagcagttgt
     5761 caccagtccc atacagaagg ccaagggcgg cactagatag atattatcca cagtttgcgg
     5821 cacaaaagca ataatgattg ataagattgc caagggaatc aaggacagaa taggtttttt
     5881 cacaattctc aatttttcct tataaatcgt taataaaaag actcccatca taaacgctag
     5941 caaggtgaga accttgtccc taacatccga aacattattt ttaattaatt ctactgaaag
     6001 aaagacaaca tttccagttt gtccagctac aagggtattc ccgcgaacaa taaaagtgta
     6061 agcatccaca tatccagcac aaaacgtcaa aaaaagtgct aaccttttag actgacgtga
     6121 tatttttctt ataggtaata acctcatttt acctcccatt gtattttctc ttagaaatat
     6181 tgtaccattt tctttctaaa aaatcgtagg ctaccattta gattttacta ttagcataaa
     6241 aataataata gacaactatt tatccaaaaa tagatagatg taacatgttt gcaaacaaag
     6301 catacgaacc tttagtaaaa tcatttccat gaaactagaa tagagccctc ttagcaaaaa
     6361 tcattatttt aatttatttc taatcactcc ttgacataaa taactctcac caataaaaga
     6421 ctatgtctta aaaaaatggt ataataaaat caatacttgg gcttgatggc tctgctacta
     6481 ataacaatta ggagagaaaa tcaggcactt gttaacaaca aggattatcc ccttgagatg
     6541 aaaggaactt tagaaatctt atgatgaaca tgcaaaacat gatgcgtcaa gcacaaaaac
     6601 ttcaaaaaca aatggaacaa agccaagctg aacttgctgc tatgcaattt gttggcaaat
     6661 ctgctcaaga tcttgtccaa gcgaccttaa ctggcgataa gaaagttgtc agcattgatt
     6721 tcaatccagc tgtcgttgac ccagaggacc ttgagactct ttctgatatg accgttcaag
     6781 ccatcaactc tgctcttgaa caaatcgatg aaactaccaa gaaaaaactg ggtgctttcg
     6841 ctgggaaatt acctttctaa aaacaaggag ctagaacaat gcttgtcgat aacaaaggct
     6901 aagaaaggtg caaaaattat aaaaaacgca taatagcagg tgtcaaagca ctcaatatta
     6961 tgcgttttct catgaaaaaa ttctcttttc atactcattt aaaatcaaaa agggaattta
     7021 tcattttacg gacatgtata ttacagattt ctataggtcg tatatagaca ggatattatc
     7081 gcttagaagt tgtccttttt gacaccaatc agtaatttag ttctcaggag ttaatggaag
     7141 tgcttttcgc acatagtttc ataactacag tatagcatag tatatcactt tatagttttc
     7201 actattgatg aactgcttga gctgctgtga tgagggtcaa cttgtaaaca tcgtctgcat
     7261 tacatccacg agaaaggtcg ttaactggtt tgttcaaacc ttgcaaaaca ggtcctacag
     7321 ccgcaaaacc acccaggcgt tcagccatct tgtaaccgat atttcctgcc tcgatacctg
     7381 ggaagatgaa gacatttgct tgaccagcta ccgtacttcc cggagctttc agagctgcag
     7441 tttcgggaac aaaggccgca tcaaattgca actcaccatc gatttcaagg tcaggacgca
     7501 agtcgtgagc aattttagtt gcttcaacga ccttatcaac gctttcacca aaccctgaac
     7561 ctttagtaga atagctcaac atggcaattt taggttcgat gccaaacatc ttagctgtga
     7621 ttgctgagtt gatggcaatt tcagccaagg cttctgcatc tggattgata ttaatggcgc
     7681 agtctccaaa taggtaacgt tccgtaccac gaaccatgag gaaggctcct gaagtacgag
     7741 ttacatttgg acgagttttg atgatttgta gagctgggcg aactgttgaa gctgttgagt
     7801 gaatcgctcc tgacaccatt ccatcaacca agcccaagta aaccaacatc acaccaaagt
     7861 agttgacatc ttcaaccaaa accttgcgta catcttcttc agtcattttg cccttgcgac
     7921 gctccaccaa ggcagaaacc atttcttcaa attgaggata atgttgaggg tcgatgacct
     7981 cataaccatc catgattcct tcaatttcaa gataaatttt aattttttca ggatttccaa
     8041 gcaaaacagg aatcacttct gtttctttta ctaagcgttt tgttgcttga agaatacgag
     8101 gctcttcccc ttcagggaga acgatacgag catttttacc aacaaggttg gctttgagac
     8161 tttcaaaaac ttccatgagt tttctccttt aagataataa ttatactttg agacagtttt
     8221 tatagagtat tagttgataa ctgggtaata aggttactga aatcatccgg caagggactt
     8281 tctaactgca agtcttgctc taaaaatgga tgataaaagg ataggtaatg gcaatgcaga
     8341 gcctgacgtt gaataccatc ttccagacta ccaccataca aatcatctcc cagcaaagga
     8401 aaaccgatat gagaaaaatg gactcggatt tgatgggttc gaccagtgtg caggtgaata
     8461 tagaccaagt gaatatttcc ataagaagct acaatcttgt atgaagtatg ggcatacttt
     8521 ccgcctttag ccactcgtct ggtaataatg gaatcttcat cacgcgcaat cggagcaata
     8581 atttcccctt ctggctccaa atgtccatct cccttaacca aagcaaagta gcgtttctcg
     8641 atagatttct tctgcaactg cttgtctaat cgtgcatggg cataaccgtg cttggcaaag
     8701 agcatcaagc cagaagtgtc cctatctagt ctggtaacaa tgtgaacctg ctgattttca
     8761 taattttgct tgacatagta acccttgata aaattggcaa tggtattaga gtgattgaca
     8821 ctaggaatag aagccactcc atagggttta ttcaagacta gaaagtggtc atcctcatag
     8881 agaatatcta atggatgctc aatagcctcc aaggtttcaa agccttcctc agcgggaatg
     8941 taaatggtaa cgtagtctcc aacgtccaat agatacgttg cattttgcgg ttgattattg
     9001 accagaatag ctccacctcg aaacttaatc ttggccagca atcccttaga aacctcgtgc
     9061 ttttttaaaa aggtcttaac cttgacatgt tcatctgcga taaattcaaa cctcattcat
     9121 ccacctcacc gataaaggca tccttaacac ggttccagaa actggtatgg ctaggagtcg
     9181 cgacaaagtg aatcttatga tggtcgattt gatactcaat acgctcaata ttacggaaag
     9241 aataaacgct attgtcaacc gaaatagtat gataatcgtt tcttgttgga ataagttcaa
     9301 tcttatcctt cttaggcaca ataatggaag agcccagtgt tcgatagaca cgattattaa
     9361 ggctggcaat ctccgttaat tgcaaagctt caatggtagg gtgtaaaaca gcaccgccaa
     9421 gagacttgtt ataggcagta ctaccagtcg gtgtcgaaac tgttagcccg tctccacgaa
     9481 aacgttcaaa gggaacacca tttattacaa tatctgccac catggttcga tcagacctgc
     9541 ggatgctggc ttcgttgagt gctctgaaaa tcttaacttc accattttcg agaaagacct
     9601 tcacattcag aacagggtaa gaaacccttg ccccagtatc tagctgcaaa ttagtcacta
     9661 gcttgtccaa ctcaaaatca cgataatctg tatagaagcc caaatgtcca gtatgaagac
     9721 cgataaagcg gaccttgtca agctgatttt cgtacttatg aaaggccgac aagagcatac
     9781 catccccgcc aatggaaatg acaatatccg gattggtatc attgagtata aactgatttc
     9841 tcttcaaacg atctcgcaat tcatacaaaa ccctttgact ctgcggtttt ctattggcta
     9901 tcagatcaat tcgtttacct gtattcttca tctgtatcgt cactgtttcc tacaccgtca
     9961 tttaattttc tactcaaagg atcaaaaagt gcctgggctt cttggatatc atcacgaatt
    10021 tcacccattt cttcatccaa ctgatgggcg attctagctg taatttccag tcgcttctta
    10081 atctcatctg ggaaatcccc ttggtacttg tagttgagag aatgttctat cgttgcccag
    10141 aaattcatgg ccaaagtacg aatttgaatt tctgccaaaa tagtcttagc tccattgatg
    10201 gtatcaaccg tatattctac taccacatga taggaacgat agcctgatgc ttttctatga
    10261 gtaatgtaat ctcgctcctg tatgattcgc atatcctgac gcttgtgcaa aatatccact
    10321 acttccttga cgtcatctac aaactgaacc atcacacgta agccagcaat atcctgcaaa
    10381 tcgtgttcca aggtcgcata agtaatgcca cgacgagcca ttttttcttt gatgctctca
    10441 attggcttga ctcgaccggt cacaaactca attggagaat gcttattttg cttacgatat
    10501 tgcttacgaa taccacgaag tttaatcttt aactcaccaa cagcttgaat gtaaggatct
    10561 agaaattctt cccattctaa ggtcatatat tctcccttgt tctcatatta tccgtcaaaa
    10621 atatctttga ttttttctcc agattcatat acaataaata caatgcttat tataccataa
    10681 atccgctttc aacgataaaa aaaggtaaga aaaatgaaac atttagaaat tgaattgaaa
    10741 acactattga aaaaagatga atacaatcgt ctaaaagacc agctcacagg tgtcactcct
    10801 gttcttcaaa caaattacta catcgacacg cctgattttg aactgcgaga aaagaaagtc
    10861 gctatgcgca ttcgaacctt tgaagactgg gctgagttga cactcaaagt cccgcagagt
    10921 gttggaaaca tggaatacaa ccaaaaattg caactaaaag atgctgagaa ctatctgagt
    10981 aaggaagaac ttcctcaagg gctagtactg gatgaattgg cgaaacatgg tatccaaagt
    11041 aagaactggc aggttcttgg ttgtctaaca acgcttcgct atgaaatgaa aacagctatt
    11101 ggtctcatgg cactggatca gagccgatac tttgatataa cagattacga attggagctt
    11161 gaagtggaaa atcatgagca aggcaaacag gatttccgac aatttttaga gaaaaatcag
    11221 atttcctacc aaaaagctcc ttcaaaattg gttcgatttg tcaaaagtat gaaaaatagc
    11281 tgaaataatc tccatttttt ggtaaaatag aaaagataaa aatacacaaa tcccagttca
    11341 tatatgtaag gtaaatataa ctaggattta taaagtttac agaggacggt ctataatgtc
    11401 agatagaaaa aacatgaaac ttttcgcact caactctaac caagagattg cacaaaaaat
    11461 tgcccaagct gttggtgtcc cacttggaaa actatcatca cgtcaatttt cagacggaga
    11521 aatccaagta aatatcgaag aaagtgtccg tggttatgat gtttacatca tccaatcaac
    11581 aagtttccct gtcaacaacc acctaatgga attgttaatc atggtcgatg cttgtgtgcg
    11641 tgcaagtgcc cacagtatca acgttgtcct tccatatttt ggctatgcac gtcaagaccg
    11701 cattgcttgt cctcgtgagc cacttacagc aaaactagtt gccaatatgc tggttaaggc
    11761 tggagttgat cgtatcctga ctcttgattt gcatgccgtt caggttcaag gtttctttga
    11821 tattccagtg gataatcttt tcactgttcc cctattcgca aaacattact gcgataaagg
    11881 attgcttggt tcagatgttg ttgtcgttag ccctaaaaat tcaggtgtca aacgtgcgcg
    11941 tagcctggct gaatatcttg atgctcctat cgccattatc gattaccctc aagacgatgc
    12001 aactcgtaac gaaggttata ttattggtga tgttgaaggt aagaaagcta tcttgattga
    12061 tgatatttta aatacaggac gtaccttctc tgaagcttct aaaatcgttg aacgtgaagg
    12121 agctacagaa atttatgctg tttctagcca cggtctcttc gtcgagggag ctgctgagct
    12181 tcttgacaat actaatatta aagaaattct tgtgactgat tcagtagcaa caaaagaaaa
    12241 aactcctaaa aatgtatgct acatcactgc tagtgagtta attggcgatg ctatcgtccg
    12301 tattcacgaa agaaaaccag tcagcccact ctttgcctac aataaaaaga aataaggtga
    12361 ttctttgatt tatttggaca atgctgcaac gactcctatg tcagcagttg ctatttcagc
    12421 tatgaccaag gttatgcaag aaacccacgg aaatccttct agtattcatg gtcatggtcg
    12481 tcaagctggc aaactcttgc gagaagcccg tcaggaacta gcccagttac taaggacaaa
    12541 acctcaacat atctttttca cttctggtgg gactgaagcc aataatacta ccatcattgg
    12601 ctactgtctt cgtcaccaag aacaaggaaa acatatcatc acaactgcca tcgagcacca
    12661 tgctgtcctt gaaacaattg attacttggt tcaacacttt gggtttgaag caaccattat
    12721 ccagccagaa aatcaagaaa tcacagccca gcaaattcaa aaggctttac gtgacgatac
    12781 gattttggtt tctaccatgt ttgccaataa tgagacagga aacctactgc ccatcgctga
    12841 aattggccaa atactcaagc aacaccctgc tgcctatcat gttgatgcag ttcaggctat
    12901 tggtaaaatc ccaattcatt cagaagaatt gggcattgat tttctcactg cttctgccca
    12961 caaattccat ggtcctaagg gaatcggttt tctctacgca tctagcatgg actttgattc
    13021 ctatctacat ggcggagacc aggaacagaa aaaacgtgca ggaacagaaa atctgcctgc
    13081 catcgtaggc atggttgcag ccctaaaaga agacctagaa aaacaagaag aacattttca
    13141 acatgtacaa aatctagaaa ctgcctttct ggcagagctg gagggcattc agtattacct
    13201 gaatagagga aaacatcatc tcccttatgt tctcaatatt ggatttcctg gtcagaaaaa
    13261 tgacctctta ctccttcggc tagatttagc tggaatttca atctctactg gctcagcctg
    13321 tactgcaggc gttgtccaat ccagccatgt tcttgaagcc atgtatggcg caaattcaga
    13381 acgcttgaag gaatcccttc gcatcagttt gtcgccacaa aataccgttg aagacctaca
    13441 aaccctcgca aaaaccttaa aagaaattat cggaggttag ccatatggca tttgaaaaaa
    13501 tcattcagtt aaaaaattgt cgttacgatt acactcttag cccttctgtt aaaaaattca
    13561 ccctcaaaga taacaccttt tttgaaacta aggttggtaa ctatgaactg actcgccttt
    13621 tggaaaaagt gccaaacagc ggtgaaggct tccaactcaa aatcatcatt aacaaggaac
    13681 ttacaggggc taaaatcaat atcactgaca agtttggcct tcgtctagtt gatattttca
    13741 aatcagaaga ccaccatatt catcaggaaa aattctactt cctcatggat agcttggtag
    13801 aacgtggtgt ctttacaaaa tcggaaagat agagccaaaa tgtttgaact gacctataag
    13861 gactgctatc atgtagagcg tactctcaag tatgaggatc atgaggctct catgttgact
    13921 ttgtcaggat gtgtaacctt accagataca ctttatgtga cttctctgac ttttaggggc
    13981 caaaaagttt atcagggtct ggtcggagac ctctaccgtt ttctatctca tgcagatttt
    14041 ttacatcaaa actaagattt ttcttagttt tttcttattt ttgttgattt tttcacaatg
    14101 tttctataaa atagaagaat agaaaggttg tgattttgtg aaagataaac agtttgctat
    14161 tccaaaagct acagcaaaaa gactctctct ctactatcga atttttaaga gatttcatgc
    14221 agaaaagatt gaacgtgcca actctaagca aattgcagag gctatcggta ttgattcagc
    14281 gaccgtacgt cgtgattttt cctattttgg tgaacttggt cgtcgtggtt ttggctatga
    14341 tgtcaaaaaa ctaatgacat tttttgccga tttgctcaat gacaactcta ttaccaatgt
    14401 catgctggtt ggtattggaa atatgggccg tgcccttctc cactaccgct tccacgaacg
    14461 taacaagatg aagattatca tggcctttga cctagacgac catcctgaag tcggtaccca
    14521 aactcctgac gggattccca tttacgggat ttctcagatc aaggataaaa tcaaggatgc
    14581 tgatgtgaag actgctatcc taactgttcc cagcgtcaag tcacaagagg ttgctaatct
    14641 cttggttgat gctggtgtga aaggaattct cagtttttca ccagtccatc tgcatttacc
    14701 aaaagacgtg gtcgttcagt atgtcgattt gacaagtgaa ctccaaaccc tcctctactt
    14761 catgcgaaaa gaggattaga aagcgaaaat cattttatga aaaaaccagt tattgggatt
    14821 acaggaaacg aaaaagctca tccagatgat gacatcatga tgagctacgc agcaaaaggc
    14881 tttgttgaag gcgttaaaga tgctggaggg attcccatca tcctaccgat tggtgatcaa
    14941 gaaatggcct gccactatat cagtttgatt gacaagctca tcttgacagg tgggcaaaat
    15001 gtcgatccaa aattctatgg cgaacccaaa accattgata gcgatgatta tcaccttcaa
    15061 agagatatct tcgaactggc cctcatcaag gaagctatta aacagaaaaa gcccattttc
    15121 tctgtctgcc gtggtaccca actctttaac gttgccatgg gtggaacttt gtaccaagat
    15181 atcgaagacc attggcagga ttcttctgtt gagtacacaa ctcaacgctt ggtaacagaa
    15241 ccagataccg ttctccaaga aatctatgga gaaatctctc atatcaactc cttccaccac
    15301 cagagcatca aggacttagc accaaattta aaagttgtgg ctcatgatcc taaagatggt
    15361 atcattgagg ctgtcatgag tacggatgat gtcgcctttc tcggtgtcca atggcatcca
    15421 gaacttcttt ttgaaaatcg tcccaaagat aagaaactct ttgactatgt cgttaatgaa
    15481 ctttagatta aatctgtctt ttcacgataa ctaaagtaat tagaatgaga gacaatcaaa
    15541 tggtccaaga gaacaatccc catcagttcg caggcttctt taacaagttt agtgacatga
    15601 tcatcatttt ggctaggcgc taccgctcct gaaggatgat tgtggaccaa gataagagaa
    15661 gtcgccatat gcttgattgc atagtgcaga atctctcgcg gttcagcgat actacgagtt
    15721 acagaaccga taaaaatggt ctgctgatgg atgatttgat tttgagtatt gagatagagt
    15781 gccaccaggt gctcttgttt tttatcccct aattcctgct gcatcttctt ggccaacttt
    15841 tgactgctga gaatactttc catttcaaga gtctcgtgtt tgtgaatacg atgccccagt
    15901 tcaatcatag cttgtaattc tatggcctta acacgcccaa taccagacaa actctgcaat
    15961 tcctgcaggg tcattttttt caaatccgtt aggcttgaaa gattgttcaa gactttttgg
    16021 gcaatttcaa aaacgctagc ttgacgtgtt cctgtcctga gtaaaatagc tagcaactct
    16081 tggttactaa gcgcttcaac tccttccttg gccagccttt ctcttggtaa tagtgaatct
    16141 tcttggaatg aaatactgta cataaaaatc ctcctcactt tattattcgt gagaaggatg
    16201 gaaaattaga tttttttctc aattggagcc acactggcta aaagtttttt caaacctact
    16261 tctgggaaat tgattttcaa ttcctgccta gcaccgctac ctgaaacttc cagaacagtt
    16321 ccctctcccc atttcttgtg gagagcaatg tcaccaatgg accaatttgc ctcgctagat
    16381 gctgattttg cgccagctgt aaattgacca aatggaagac cgcttgactg gattgatttt
    16441 ggggcagcac cgcgtttacg gtcttgaaga gcctgagcca aactcatacc ttgaccaaag
    16501 gaaatactac cactgctata tgatgcctta aagcttgtat ttgcaggacg agccagacct
    16561 tgatactcaa gcaagtctga actgatttcg ttaataaaac gagtcggacg gttataattg
    16621 gtacgaccaa aaagcaagcg tgagttggca ttggtcagat agagaatttt ctctgcacgc
    16681 gtgataccta cataggctag acggcgctct tcttctaatt catctggatc ttcagtcgca
    16741 cgactaagtg gaaagacatt ttcttccatc ccaatcaaaa agacaactgg aaattcgaga
    16801 cctttggcag catgcagggt catcaaggtc acttctgatg tctcctgact acctgaatct
    16861 gtgtcggcaa tcaaagccaa gtcatttaag aaacgactca gtttgtccag accagtttcc
    16921 tcttctgtca catcagtggt gtcatcaaag ttcttcgtaa cagaaagaaa ctcttcgata
    16981 ttttcaaccc gtgccctgct ttctagagtc gcttgggcgt taagaatatc gacataacct
    17041 gttttttcta ggacggactc aaccaactct gtaatgctta agtggtctag ctgctcccgc
    17101 aaatcaagca tcatattggc aaaatcccag atagattggg ctgccttacc cttaatacca
    17161 gacaacataa tattagcaga agcatccagc atggacatat tttgcaaatt tgcaaaatca
    17221 cggattttct caactgtacc tagaccaatt ccacgtttag gctcgttgat aatacgctca
    17281 aaactaatat tgtcactcaa attagcaata aggttgagat aagcaataat atcgcgaatt
    17341 tccttacggc tgtagaattt ggttccgcca accatggtat aaggaatgtt agacttgagc
    17401 agggcttcct caattgtacg ggactgggca ttagtccgat agagaactgc aaaatcctta
    17461 tgaaggaagt tttgactgcg actaagttca tcgatggttc tggctacaaa tacagcctca
    17521 tccagctcat catcggcacg atagtaaacg atttgctccc catcagcgtt ttgagtccag
    17581 agatttttag gacggcgatt tttattgttt ttaataacct cgttggccgc ttggagaatg
    17641 gttttggttg agcggtaatt ttcctccaac aaaacaacct tggctttggg gtaatccttt
    17701 tcaaagtcca agatattctg catatcagca ccacgccaac cgtagataga ctggtccgca
    17761 tccccaacca cacagatatt tttaaaacgg gaagccaaga gtttgaccaa ttggtactga
    17821 gcgtggttgg tatcttggta ctcatcaacg tggatgtatt ggaatttttg ctggtagtag
    17881 gtcaaaacat caggattttg atcaaagaga cgcaaggtca gcataatcaa atcatcaaag
    17941 tcaacggatt cggactgacg aagttctttt tgataggctg tataacactg ggccacaatt
    18001 tgcgtataca tatcgccagc ttgggcagca taagcaacat catcaatcaa atcattctta
    18061 gcattggaaa tggtccccaa aatagttcgt tcattccatt ttttaggatc caagttcaac
    18121 tgttttagaa tacgtttcat gagcgttcgc tgttcaccag gatccacaat tgtaaaatta
    18181 cgattgtagc caatatggtc cgcatctcga cgcaaaatac gcacacacat ggagtggaag
    18241 gtcgcaatca gacagtcctg agtagctgga ttgaggctat aagcacgctc tttcatctca
    18301 cgcgcagcct tgttggtaaa ggtaatggcc aagatattcc aaggattgac cagcttttca
    18361 tcaatcaaat aagcgatacg gtgggttaaa acacgagtct ttccagaacc agcccctgcc
    18421 atgattagca agggaccttc tgtcgtttgc accgcctcag cctgacggtc attcattcca
    18481 tttaataatg cgttcatctt ctcttcctta ctcttgaagt caatatttct attatatcag
    18541 aaatcaggga aaatagaaac tttacgggga gtagcaaaat atagtggatt gaaactagaa
    18601 tactacactg tgggtttcta aaacactcga cttttcaccc aattttttca taaactagct
    18661 caatac
//
LOCUS       DAVEHY010000046        16267 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVEHY010000046 DAVEHY010000000
VERSION     DAVEHY010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.046"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(62..1351)
                     /locus_tag="VUZ44_001895"
     CDS             complement(62..1351)
                     /locus_tag="VUZ44_001895"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU0320758.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1431..2678)
                     /locus_tag="VUZ44_001896"
     CDS             complement(1431..2678)
                     /locus_tag="VUZ44_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU0320759.1"
                     /translation="MKLLFRNPAYRILTLSCFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGDLGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2871..3722)
                     /gene="rgg"
                     /locus_tag="VUZ44_001897"
     CDS             complement(2871..3722)
                     /gene="rgg"
                     /locus_tag="VUZ44_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU0320760.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSAFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3846..4187
                     /locus_tag="VUZ44_001898"
     CDS             3846..4187
                     /locus_tag="VUZ44_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU0320761.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4245..4325
                     /locus_tag="VUZ44_001899"
                     /pseudo
     CDS             4245..4325
                     /locus_tag="VUZ44_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4441..6144)
                     /gene="ilvD"
                     /locus_tag="VUZ44_001900"
     CDS             complement(4441..6144)
                     /gene="ilvD"
                     /locus_tag="VUZ44_001900"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU0320762.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6377..7309)
                     /locus_tag="VUZ44_001901"
     CDS             complement(6377..7309)
                     /locus_tag="VUZ44_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU0320763.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSSSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7306..8163)
                     /locus_tag="VUZ44_001902"
     CDS             complement(7306..8163)
                     /locus_tag="VUZ44_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU0320764.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(8167..9513)
                     /locus_tag="VUZ44_001903"
     CDS             complement(8167..9513)
                     /locus_tag="VUZ44_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU0320765.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMIQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(9526..9810)
                     /locus_tag="VUZ44_001904"
     CDS             complement(9526..9810)
                     /locus_tag="VUZ44_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU0320766.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(9814..11844)
                     /locus_tag="VUZ44_001905"
     CDS             complement(9814..11844)
                     /locus_tag="VUZ44_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU0320767.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            12035..13042
                     /locus_tag="VUZ44_001906"
     CDS             12035..13042
                     /locus_tag="VUZ44_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU0320768.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            13045..13245
                     /locus_tag="VUZ44_001907"
     CDS             13045..13245
                     /locus_tag="VUZ44_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU0320769.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            13397..13579
                     /gene="rpmF"
                     /locus_tag="VUZ44_001908"
     CDS             13397..13579
                     /gene="rpmF"
                     /locus_tag="VUZ44_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU0320770.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            13595..13744
                     /gene="rpmG"
                     /locus_tag="VUZ44_001909"
     CDS             13595..13744
                     /gene="rpmG"
                     /locus_tag="VUZ44_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU0320771.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(13836..14396)
                     /locus_tag="VUZ44_001910"
     CDS             complement(13836..14396)
                     /locus_tag="VUZ44_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU0320772.1"
                     /translation="MNISGERAVEGLRDEKERYRAILKTKESVRTIPMSPKVEQILLK
                     YIERNKFQARFNPTYHDMGYIFTRVYIKGKNQQGSPLYHTEISMFLRGGTSQSVKYNK
                     KSGKSYKDIDDLVDFGRPVHIVPHMFRHSFVSVMADKNVSLNVIREFVGHSEDSREIE
                     KIYLHVMQKGKHKIEQAMIDLSKIIS"
     gene            complement(14472..14789)
                     /locus_tag="VUZ44_001911"
     CDS             complement(14472..14789)
                     /locus_tag="VUZ44_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320773.1"
                     /translation="MKTFKELVDIEGMVFPNSHGVKRVQRFNPDESPCFLLDDESREL
                     LMRKLPFDKINEPTLKKFAENIIVLNRQKHRVSDKSRMVLMNEANYSYSGESFYTTIV
                     EYY"
     gene            complement(15077..15262)
                     /locus_tag="VUZ44_001912"
     CDS             complement(15077..15262)
                     /locus_tag="VUZ44_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320774.1"
                     /translation="MAKLTNFYLNKQNEINLPRLAKFFKEKNMLERENRTWVINLAIK
                     ELFESLESEIIDFENNN"
     gene            complement(16158..>16267)
                     /locus_tag="VUZ44_001913"
     CDS             complement(16158..>16267)
                     /locus_tag="VUZ44_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU0320775.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         5284 a         3386 c         2668 g         4929 t
ORIGIN      
        1 acaacctcaa aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
       61 tttattgagt ataaaatcct agtttttcaa agatttctga gaagttttgg ctgattgtct
      121 caagtgacac ttgcacttct tctcgagttt ggttgttctt gaccgtcact tgtccgcttt
      181 cgacttcgct ctctcctagg gtgatgaggg tcttagccac aaagacatcg gctgacttga
      241 actgagcttt tagtttacgg ttgaggtaat cacgctctgc tttgaaacct tgttggcgaa
      301 gagcctgtac caattccaag gccttgatat ttgccccttc gcccaagact gcaatataga
      361 catctagggc gttttcgata gggagggtca cgccttgttt ttcaaggatg agaagcaggc
      421 gctctacacc aagtccaaaa ccaaatccag cagtttcagg gcctccaaag taagcaacca
      481 aaccatcgta gcgaccaccc gcacagactg tcaagtcatt gccctcaatc tctgtgataa
      541 actcgaaaat ggtgtggttg tagtagtcca gaccacgcac catattggta tcgatgatgt
      601 aatctactcc aagattttcc aacatctgac gcacagcatc aaaatgagtt tggctttctt
      661 catcaagaaa gtccaagata gacggcgcat tctctactgc caccttgtct tctttttcct
      721 tagagtccaa gacacgaaga ggattttcct ccaagcgacg ttggctatcc ttagacaagg
      781 tctccttgag cggtgtcaaa tagtcaatca aggcttggcg gtaggctgca cggctctcag
      841 gatttccaag agtgttgagg tgcaatttga caccttgaat accgatttcc ttcaaaaaat
      901 gggctgccat agcgattgtt tccacatcgg tagctggatt gctagagcca aaacactcaa
      961 caccaatctg gtggaattgg cgcaagcgcc ctgcctgtgg acgctcataa cggaacatag
     1021 gtcccatata gtagaacttg cttggctttt gcacttctgg ggcgaagagt ttattttcca
     1081 cataggaacg gacaacgggt gcagttcctt ctggacggag ggtaatatga cggtcaccct
     1141 tgtcataaaa atcgtacatt tccttggtta cgatatccgt tgtatctccg acagagcgac
     1201 tgataacctc gtaatgctca aaaataggcg tgcgcacttc cgcgtagttg tagcgtttga
     1261 aaatttcacg ggcaaagccc tcaacgtact gccacttggc agattcagca ggtaaaatat
     1321 cctgcgttcc ttttggtttt tgtaatttca tagggaatcc tctttaaact taatagtctt
     1381 attttaccac aaataaaggg attaaaacag tgagaaaaaa aaattaggat ttagatatca
     1441 tttttgagat taagaattgt taaaaaaata gctagcaagg aaagaccaac aaatagcatc
     1501 caagtcaact gtatattcca tacggctact agtgaaaaac aagctgttcc cacaggtatg
     1561 gataaggtaa acaatagacc taaaaaatta ctagtacgag ctagaacctc tggagctaga
     1621 tttttcatga gcatggcact aatctttggt tgaactttac cagacacata cagagtaaag
     1681 aagagaaata gcaaaccaag cacgacttga ttgaataaat tagccaaacc aactagacta
     1741 agccctacgg tcgcccacat catcaatcta ggcaaggact gcttcccaaa ataatcattg
     1801 cccgtaaggc tactgatgat gactgctact aaaacacaga attgattgat aaatagtgcc
     1861 tctgtataag aaaaattcaa gagagaatgg ctcaaaaaga agatattata aattccaccc
     1921 aaatcgccac ccaaggaatt aataagcaag acagcaaaga gcataaaacc aaagtttttc
     1981 tgcccacttt taagaaaaac gagacgtaaa tttcggtaaa ttgttaggaa ctggtctttg
     2041 atagaaagct tctcattttt taagttttca ccatcagcag atgacattga caggctcaat
     2101 ttgctttttc ctaaaaagag gatagtggct gatactagga aaaagcaggc attgattccc
     2161 gcaacgagag aaaaattgtt gaccgataga gctaagagcc agactccgaa agcttgacca
     2221 ccaatagctg aaatataggt gatgaactgt gaaaaagaat aagcctccat caaatcatct
     2281 tcagctactt tttccttaat aagaggcata cgcaggccac ctgcaaaatc actgatgata
     2341 tcactaatga cattgatcaa acacaggcta gaaaaggcaa agagactagc ttgctgaaca
     2401 actagggctg ctagaaaaaa tagaaccgcc tgaaacaaac cgctatagac catccatttg
     2461 accttgtccc tcgtgtaatc tgcccgaatc cctacaaaaa ctgtaaagag ggtcggaaga
     2521 atcatgacaa tattcgccat agcaacagca aaagatgctt gtgacaaggt cgatgcatag
     2581 acgataaaga ccaggttgaa aatcgaagca ccaaaagcat tgaagaagca tgataaagtc
     2641 aaaattctat aagctggatt tctaaacaat agtttcatag ataatctccc ttcttgttcg
     2701 aacctctata tgaagtatga ctatagtata gcacttagaa atttgagagg gagaactctt
     2761 gaatatatgc aacaaataaa atgagcaaaa agaaacgata gaacttttgt aatgacctga
     2821 gagagggcaa tagttctatc gcttcaaatt ttttcttggt ttgcagatat tcaacattcg
     2881 gtcgtatttc tatagtattc ggcagattta ttacagccaa gcatctcaaa aatacggaca
     2941 gcatcctcca tctttttctg gccttccttg actctacctt gcttgctatc aaggagacct
     3001 tctgcccaca gataaacaat tcggaaatag gtctcatttt ccttgtagaa atgctcttcg
     3061 ataacacgtt taaaataata ggcattggta aattcttcac actcaatact agctaaaaag
     3121 ccattcaata gtatagtatg aaaaaagttt cgattaccag acatttccat tagaaaatca
     3181 gatttacgta ccatttctcg tacatatcta gtaaaaagag aaacagataa aaaggcagaa
     3241 ctgactgaaa ataaattgag ttcatagatt ccccagatct cggtagaaaa caaataatca
     3301 tgaaggactt ttccttcctc tgctgttaac tctacccttt catccatgct cttcatataa
     3361 gacttgatca taatggcatt tagaatatgt ttctgtttgt tgtgagaatg ggcatgcttt
     3421 tgatactccc tgcgatataa gtcctcaaga ggtgctatat tctttggttc caagacatct
     3481 gtaatttctt ttctcaactc agaatctgta tcatactgga aacctctcgc cagaaagagg
     3541 atctcctcca cactggcaga tatattttcc agagcaaata gaaacttttc caccgaaagc
     3601 tcactctgac ctgtttcaaa acgggacaac atagacggcg aaaattgtcc tccggttgct
     3661 tgtctcagtg agatatttct tgattctcgt aattgtctaa agacttttcc aatctgctcc
     3721 atagacttcc ccttgattcc gtattttctt cattttatca tatttttcag aaaattcatc
     3781 aaaaacttgc caaattgtca gaattatgag aaaatagagg atatttatca cgtggaggga
     3841 ctgctatgag agacgatatc aaaatcaatg accgtgcttt ggccttgcaa gaccaaatta
     3901 tcgaaaaact agagaaagtt tttgatacag atgtggaatt ggatgtttac aatctaggtc
     3961 tgatttatga aatcaatctg gatgaaacgg ggctctgcaa gattgtcatg accttcaccg
     4021 atactgcctg tgattgcgcc gaaagcctgc ctattgaaat cgtggcaggt ctgaaacaaa
     4081 tcgagggtat caaagatatc aaggttgaag ttacctggtc gcctgcctgg aaaatcacac
     4141 gaatcagtcg ctatggccgt attgcccttg gactaccacc tcgttaagca ggccaatcac
     4201 ttttaaagat gaaaaaagca agccgaaaat ggcttgcttt ttgatactca atgaaaatca
     4261 aagggcaaac tagaaaacta gccgcaggtt gctcaaaaca ctgttttgaa gttatggata
     4321 gaactgacga agtcagctca aaacactgtt ttgaggttgt agatagaact gacgaagtca
     4381 gtaaccatac ctacggcaag gcgacgttga cgtgatttga agagattttc gagtatgagt
     4441 ttatttttta cctgacttgt ccatattcca gaagtctgtc acggctccgc gtgaagcaga
     4501 tgatacgatg tgggcatatt taccgaggac accacggctg taaagtggtg gcaaggttgt
     4561 ttctgccttg cgtttttcaa gttcttcttc ggatacggcc atggaaattt ctttggtatc
     4621 ttggtcaacc gtaacgatat cgccggtacg gagataggca attggtccac catcctgagc
     4681 ttcaggagcg atatgtccaa caaccagacc ataagtacca ccagagaaac gtccgtccgt
     4741 caagagggcc accttatctc cctgaccttt accaacaatc attgatgaaa gtgacagcat
     4801 ctcaggcata ccaggaccac ctttaggtcc aacaaaacga acaacgacta catcgccatc
     4861 aacgatttca tctgtcagaa cggcctgaat cgcatcttct tctgagtcaa agaccttagc
     4921 tggcccaacg tgacgacgca ctttaacacc tgataccttg gcaactgcac cgtcaggagc
     4981 aaggttcccg ttcaagatga taagcggacc atccgcacgt tttggatttt caagtggcat
     5041 gataactttt tggcctggag tcaagtctgc aaagtcagcc aagttttcag ctacagtctt
     5101 accagtacat gtgatgcgat ctccgtgaag gaaaccattt gccaacaagt acttcataac
     5161 cgcagggaca ccaccgactt cgtagaggtc ttggaagaca tactgaccag atggtttcaa
     5221 gtcggccaag tgaggcacac gttcttgaat cgtattgaag tcctcaagtg acaagtcaac
     5281 atttgcggca tgggcaatgg cgagcaagtg aagagtggcg tttgtagaac caccgagagc
     5341 catcgttaca gtgatagcat cttcaaaggc ttcacgagtc aagatatctg atggtttgag
     5401 accaagttcc aacatcttaa caacagcacg tcctgctgct tcgatatctt ctttcttatc
     5461 agctgattca gctgggtgag aggatgaccc tggcaaactc atccctagaa cttcgatagc
     5521 agttgccatg gtattagcag tatacatacc accacaacca ccagggccag ggcaggcatt
     5581 acattcaaga cgtttcacgt cctcagctgt catgtcaccg tggttccatt ttccgatacc
     5641 ttcaaagaca gaaaccaagt cgatatcttt accatcaaga tttcccggtg caatagttcc
     5701 accataggcg aaaatagctg ggatatccat attagcaata gcaatcatag atccaggcat
     5761 gttcttgtca cagccaccga tagcgacgaa ggcatccacg ttgtgaccac tcatagccgc
     5821 ctcgatggag tccgcgatga tgtcacgaga tgttagagag aaacgcatac caggcgttcc
     5881 catagcgatc ccgtccgcta cggtaatggt tccaaactgt acaggccaag cgcctgcaga
     5941 tttgacacct tctttagcca gtttcccgaa atcatgcaag tgaatgttac atggtgtatt
     6001 ttccgcccaa gtcgaaatca ctcccacaat cgatgtttca aagtccttat ctgtcatacc
     6061 agtcgcacga agcatagcac ggttaggtga tttaaccatg ctgtcataga tgctactgcg
     6121 gtgacgttta tctaattcag tcatcttatc cctcccattt cagtttttac tattatagca
     6181 caatttaaag gcaatgaaca gaataaaatt cttgaatttt cagaaaattc tatacacatg
     6241 tgaaatattt aaaattaaaa acaacaaagc ggattagtgc actttctgat gaccagaata
     6301 tgctttttaa tccgctttct ttaaataacg tactgtaatt tttacagaaa ttctttcaga
     6361 taagtgtatt taacatctat cttgcattat aaatttctag aaccttctct tttatattcg
     6421 attcactcaa accatactca ttaagaagat aatccatttt ccctacttga ccgaatcttt
     6481 cttgaacacc catccgatga atttttgtta ttccatcatc agagaataat tcacataaag
     6541 cactgccaat tccacctatc tgattgtgat tttctacagt aaatatagtt tttccactta
     6601 acattgtttt tatctgttct ggtatcggtt tgattctaaa taaatctatc acacctactg
     6661 aataacctaa tttagacagt tcatctgcaa ctcgaatact tggagcaacc attatgccag
     6721 aagcaacgat tacaagatct tcaccatgcc ttaactcaat gtagccttta gaaaaatctt
     6781 ctccaccttg atatacagcc tctggagctt ttctaattgt tcgaatatat tttagtcctt
     6841 ttaagtctaa tgtctgattc aatatttcac gaaattggat atcatcagtt gcttcgaaaa
     6901 tgattgattt aggaattaaa cgtaacaagc caatttcttc aaatggcata tgtgtcccac
     6961 cattcatttc tgcagttact cctgcatctg atccaatcac agtggcatcc aattgtgcgt
     7021 atccaagaga aataaataat tgatcaaata cccttcgtga agaaaaagga ccaaatgtat
     7081 gaagataagg tctaaacccc tgaatagaca agcctgctgc aaggccgacc atttctgctt
     7141 ccataatccc aacattcaca taacggtctc caaagtcctt ttcaagatta tgagtagcca
     7201 tcgaacttga caaatcggct tctaagacta ctatatcaga agaactttga ttagcctcta
     7261 aaaggaagtc tctatataca tgccgtaatt ctttcgtact tctcatcatt ctgtttcctc
     7321 caattcctga cttaatcttt ctacaactga agttaacatt tgtttctcct ctacagtagg
     7381 gcgaagatga tgattggatt tcatttcttc cagctcttga accccttgac ctttaatagt
     7441 atctaataca atgcacttag gtgatgaatt atttgactgt tttaattgga caatcccttc
     7501 ataaatttct ctaatatctg aacccttgac cctaatggat tcaaatccaa atgctgaaaa
     7561 tttttctacg aaatcacctg gattacaaat atcctttgta aaaccatcta attgtttttt
     7621 gttatcatca acaaatacaa ttaagttgga taactgttga tgagaagcaa actgtatagc
     7681 ctcccaacat tgtccctcat ttaactcacc atctccaaca atagcataag tataaaaggg
     7741 actctttctt attctctgac catatgcaag tccagttgca acactaattc cttgtcctaa
     7801 agagcccgtt gtcatatcta tgcctggcgt tagatttcta tcaggatgag acggtaattt
     7861 ggttccattt gtatttaaag aatataggaa ttctttgtca aagaaaccat tcaaatagag
     7921 tgtactgtat agagctggtc ctccatgacc ttttgataat atgaaataat ctctatctcg
     7981 tgctgcaaat atttctggag tcattggcat tatttcacca taaagcactg ctaaaacttc
     8041 tacgatagac agacttcctc cgtaatgtcc gaatccaaga tgattcaatg ttctaagagt
     8101 atttaatcgg atgttagtcg caaattttct taactcatct tctctatttt tacttaaaat
     8161 catcccttat tcctcctttg cagatggctt tttaataaag gatactccaa acataactgc
     8221 tagaataaga acaagaccaa tcacaatgcc tgcttgtgag ccaaattgat ttaacattcc
     8281 taaaataatt cctgatagac caaaatctgc atctgagaaa gttgatcctt ggaaaccaag
     8341 tcctcccaaa actggcatta aaaagactgg aagaaaactg attaaaatac cttgtaaaaa
     8401 tgctccaata gtggctccac gaacaccacc agatgcattc ccaatgacac ctgcagtcgc
     8461 tccacagaag aaatgaggca caacacctgg taagataaca accgttcctg aagcaatcat
     8521 aattgccata cttactaaac caccaataaa actagagata aatccaatta gaactgcatt
     8581 gggtgcataa gtataaacaa tcggacaatc caaagcaggt tttgaattag gtacaagacg
     8641 ctctgaaata cctttaaagg ctggaacaat ttcgcccaaa ataaggcgaa cacctgctaa
     8701 aataacaaat acccctgctg caaattgacc tgctaattgt aaagcataaa ctagaccact
     8761 tgtaccacta ctgatttctt tttctatata ttctgaccct gcaaagatag ctacaataat
     8821 gtaaataact gccatagata aagtgatact aacagtacta tcacgtaaaa aagctaaact
     8881 ctttggaaat ttaatgtcct ctgttgattt tgatttgtca ccgataaggc taccagtaaa
     8941 accactcaac caatatccca aagaactgaa atgacctaaa gccaccttgt catttccagt
     9001 taattgaatc atatattttt gcacaaatgc tggggaaata ctcataataa taccgagtgc
     9061 taatcctcct agtaagatga gaggcaagct agtaaagcca gcaactgata aaatgaccgc
     9121 aatcatacat gccatatata gagtgtggtg ccctgttaaa aaaatatatt taaatcgagt
     9181 aaaacgagcg attaagatat tgaacaccat gcctgcaaac ataatcattg cagtagctga
     9241 gccatatgtt gttaaagcta cagctacaat tgcttcatta ttcggcacaa cgccagataa
     9301 atgaaaagca tgctcaaaca tggtaccaaa tggatttaaa gaattttgta caattcctgc
     9361 accaccagat acaactaaga aaccaacaaa ggtcttaatt ccacctttaa taatatcagg
     9421 taatttcttc ttctgaagaa ctaatcctaa aattgcaatt aaagctacta aaatagctgg
     9481 tgtactaaca atatccaata tgaacttcat catgacgcta gcctcctata taagtccttt
     9541 ttcttcacaa agtttagtaa ttaattctcg tagttcatcc atatcaataa tactatttaa
     9601 gatacgaaca tctccaagat gactagctga atcagctaga tcacgaccaa caatccaaat
     9661 atcagctgca tttggatctg ctccacctaa atcataatgt tcaacttcta catccgaaac
     9721 attcaaatca ctcaatacag attcaatatt catctgtacc ataaaacttg aacctaatcc
     9781 tgaaccacaa gctgtaccaa tttttaacat tatctaatcc tcctgtttaa ttatcatttt
     9841 aatgtcatca tagttttttg atgaaattaa agtttgaaca tgatttttat ctcttaaaat
     9901 tgttgttaaa tgtgacaaag cctttaaatg actctcatta tcaatggctg caatacaaat
     9961 caacaatctt acctcttgtt ctggattatc caataaataa atcggttctt ccaaaactaa
    10021 cattgacatt cctatttcat tcacaccttc atctggccga gcgtgaggaa ttgctactcc
    10081 cttccctaaa ttaataaaag gtccaaactc ttctactttt tgaatcattg cctcagggta
    10141 gttctccgtt atcttatctt gatccaaaag cggtttagct gctaaacgaa tcgcctcctt
    10201 ccatcctaat ttttgcgaac taacctgata ggtttctttg gtaataagtt gttctagcac
    10261 tggtacaatt tcctttctat catttttttg ataaagataa ttctttaacg ccaatcttaa
    10321 ttccaattct tgtgtaataa ttccatatct tttgacaata ttcaggattt gttcaatctc
    10381 aaaatctcca tactctaaat tcggaaaatc ttttaacact agttctacta gttgtattgc
    10441 ttgctcttca gtcatcataa ccgaaactag ataatttggc ttttctgtct ccacctttat
    10501 ggtagaaaaa accatatcat agtcactact agctttcacc tgtaaatcat caatctttga
    10561 ggttcctata aactcaattt gaggaaataa tgctaataga ttctctttta acatcaatga
    10621 agaactaaca ccattaggac aaatgattgc tgctttatag catttttgag gcaaagtatc
    10681 tgctttcttt aaataacctc cgaaatggat aacaaaatat gctgtttcac tatcaggtat
    10741 gggattgtca atagcgtcca tcaagggcat caaagaatct ttgactaatt caaataaatc
    10801 aggataatgt tctttaacat gcaatacata ttcatttgaa ctaggtaggc cgaactttaa
    10861 tctatagtaa gccggtataa ggtggcggcg aagattttct ctcaatcctt ccctttgttt
    10921 aaaatgtaac aaagaaatat cttccattct acttataata gcctctgtta attgattaaa
    10981 gtaaaccgga gcaacatcta cttcaccttc aaagcaactt gataataaaa ctgtgatata
    11041 gcgataatca tcctcagaaa acaccgtatc tataattccc aaatcaacca ctgtatccaa
    11101 taaaatagtc gttatatctt gaataacagg agatactaat gtctctgaaa gacatactct
    11161 ttcaacatcc ctttgatacc tacacagaat gaatactaaa ccgaaaaggt aaacttttaa
    11221 ttgattaaca ataggtacta gctgtagctt ctcataataa tctttaacta cctgatcaat
    11281 caaatcataa gttaatgaat acccccaact ggataaaaca taatccaaac cccaaatccc
    11341 tatggaggat tccagcaact cactaaccat ttgaaaagct aaacggtgct tattccactc
    11401 tgaaccgtgt aaagtataac cttttgctct actgtaccct agctccaaat cattatctaa
    11461 cataatcttt cttaatgatt gaatatcaga taaggttgta ttcttactta ctttcaaaaa
    11521 gtcttggtaa tgattattcg atataaaatc taatcggcaa aaagtgtaaa gatagattaa
    11581 agctaagcga gtcgactttg gtaaaaccaa ttcatccgac ttaataatat ctgtcaaaga
    11641 ctgcttcgta cgatttgata aactatagcg accttgtttt ttatccagca ctatcccttt
    11701 attagctaga taaggcacta aataatctat tccttctttg acttccttta taggtaagct
    11761 caccttaaca gataattcat ataatgatag ctcacaatga tccatcaaag tcatcaaaat
    11821 aactagtgct ctataatcaa acatttctct tcctttctaa ctacaattat agtgtaaaaa
    11881 ttataagaat aaaagagtat ttgagcacaa tataatctca ccttttaaaa gaaattattg
    11941 ggctgaaact ttttagtgat tattttcaac tttctattga cttttaaaaa caaagtgata
    12001 tcatttagat atcaaataac aggaggtcat tcttatgact gaaaaactaa tcaattcaaa
    12061 accaaatggt gtattcgcat tgattctcat tgaattgacg ctcgtacttg gtgtctttat
    12121 atttataatg ggtgttggtt cggaaaacat ttttggaatt attatcggac ctttactaat
    12181 cgtaattgca ggtctagctc atgctggttt aaaagttgtc aaacctcagg aagctctggt
    12241 tctgacactc tttggtaatt atacaggtac catcaaagaa cctggttttt actttgtcaa
    12301 tcccttcagc gtagcagtca accctgcaaa ccacactcga cttggacaaa gtggtgatgt
    12361 tagcacaaaa tctccttttt taggagctaa atcatcaaat gacaatgatg taaatcttga
    12421 aattggcaag aaacacattt ccctcaaagt catgaccttg agcaattctc gtcaaaaaat
    12481 caatgattgc ttaggaaacc ctgtagaaat cggtatcgcg gtaacttgga gagttgtcga
    12541 taccgctaag gcagtcttca acgttgataa ctacaaagaa tatctttcat tgcaatgtga
    12601 tagcgccctc cgtaatattg tccgcatcta tccttacgat gtgtctccta atgtggatac
    12661 tacgggtgac gggcaagcag atgaaggtag tctccgtggc tctagcgaaa ttgttgctaa
    12721 ccgtattcgt gaagaaatcc aaagtcgtgt tgaggatgct ggcttggaaa tccttgaagc
    12781 acgtatcact tacctagctt atgctccaga aattgctgcc gttatgcttc aacgccaaca
    12841 agcatctgcc attattgatg cacggaagat gattgtagat ggtgctgtag gaatggttga
    12901 aatggcacta gaacggctca atgaagggga attggtagaa cttgacgaag aacgaaaagc
    12961 tgccatggtt tcaaatctcc ttgtcgttct ttgtggcaat catgatgcac aaccaattgt
    13021 caacacagga agtctttact aaagatggct gaagctaaaa aaaagcagat cccccttcga
    13081 ctctcaacaa agttatacgc tgcactcgca tcatgggcag aagacgactt tcgttcagtc
    13141 aatgggcaaa tcgaatatct cctcacagag tgtgtcaagc aacggaagaa agacggaaaa
    13201 tacgtatcag aaaccattga cgaaccattt gagattgata tttaacatct tctcctgtct
    13261 gacaagtcgg acaggagaat tttttcatct ttttttgtca agtaacttta ctttacaaaa
    13321 aaaatgtgtt atcctagtat ggttgatgaa aatcagtaga ttgaatcgaa tataaatacc
    13381 taaaggagaa atcaaaatgg cagtacctgc acgtcgcact tcaaaagcga agaaaaacaa
    13441 acgtcgtaca cactacaaag taacagctcc atctgtaaac tttgacgaaa ctactggaga
    13501 ttactcacgt tctcaccgtg tatcacttaa aggatactac aaaggacgta aaatcgctaa
    13561 agctgcatca gctgaataat agaagggaga taccatgcgc gtaaatatta cacttgaaca
    13621 caaagaatct ggtgaacgct tgtaccttac ttctaaaaac aaacgtaaca ctccagaccg
    13681 ccttcaattg aagaaatact caccaaaact tcgcaaacac gttgtgttta cagaagttaa
    13741 ataatacaac atacagaaag cctatgaaat caacatttct aaggcttttt cttttaagtt
    13801 tagcaaaata actgaatttt aactgattat aataatcaag agattatttt agacaaatct
    13861 atcatagctt gttcaatctt atgttttcct ttttgcataa catgaagata gattttttct
    13921 atttctctac tatcttctga atgtcccaca aactctcgaa taacgtttaa gcttacattc
    13981 ttatcagcca tgactgaaac aaaactatgt cggaacatat ggggaactat gtgaacaggc
    14041 ctaccaaaat caactaggtc atcaatatcc ttataggatt ttccactttt cttattatac
    14101 ttaacggact gactagttcc acctcttaag aacattgaaa tttctgtatg atacaatgga
    14161 ctgccctgct ggttcttccc ttttatgtat accctagtaa aaatatatcc catatcatga
    14221 taagtcggat taaatctcgc ctgaaactta tttctttcaa tatatttaag taaaatttgt
    14281 tctacttttg gtgacatcgg aatagttcta acgctttctt tagtttttag aattgctcta
    14341 tatcgttcct tctcatcacg caagccttcg acagctcgtt ctccagaaat attcattaac
    14401 tttcattttt atatttttcc tttcaatttt caaaaacaaa gggaaggatt aacctaacct
    14461 cccctaccaa gttaataata ttcgacaata gtagtataga atgattcacc actatagctg
    14521 tagttagcct cattcatcaa taccattcta gatttatcag atacacgatg cttttgacga
    14581 tttaatacaa taatattctc agcaaatttt ttcaaagttg gttcattaat tttatcaaat
    14641 ggtaattttc tcataagtaa ctccctagat tcatcgtcta aaagaaagca tggtgactcg
    14701 tctggattaa acctctgtac acgtttcacc ccatgagaat taggaaagac cattccctca
    14761 atatcaacca gttctttaaa tgttttcata ttttctttct ccttaaatta aaatcttaaa
    14821 attaaatata gcttattttt gaaattatat cttgcatgga gaagctcgac tgttactcat
    14881 attcataacc tcattttaaa attatatttc ttatatgttt caaacataaa tcacgtatat
    14941 attatggtta tatcatatca tgccgaggag gaaaaatcaa gacctcaaac attacatctt
    15001 tgttgcatat gtattacata tcaaatacat gaatatatat ttattgttgc aaaaaaaaag
    15061 acgctcagtg cgtcaattaa ttattatttt caaaatctat aatctcagac tccagacttt
    15121 caaaaagttc ctttatcgct agattaatca cccaagtcct attctctctt tcaagcatat
    15181 ttttttcttt aaaaaattta gctagtcttg gtaaattaat ttcattctgt ttattcaaat
    15241 aaaaatttgt taatttcgcc ataatattcc tcctacataa tatatatcat aaaaacacat
    15301 acttttcaag taattcctat ccaaaaactt ctctacacac tttgtacatc tgatataata
    15361 cctttgatga actatcataa cgagtaattt tgtttaatac ttctacaaac taatgtactc
    15421 cataaattga aactacaacg cccttatcta attaagaaaa tatctaacct atgataaagc
    15481 aatactaata agtgctatat tctgatttcc aaagaatatt aatttatcgt aactgattcc
    15541 taactgatta aatttcaata aattcatatt tctctattta ccatttattt tattttaggt
    15601 agaaaagcta tcaaatcaag gttttcaaat atcattacat acctttaaaa caacatcttc
    15661 ttcacagaag tgaagtaagc attcaatacg aatcaataca gaagaaaaac gcttgatcag
    15721 cgttttttct ttttgttaat ttcactatat tgcaagggaa atcattcgaa tgactacctt
    15781 ttttgaaata agaatacgga ttcggacaat taaaagcaag aggaactcaa atgtaagttg
    15841 gggttccttt tttgtatatt tttcaaataa cgcctctaca ctatttgtag caaattcacc
    15901 aactacagtt gtatcttagt taaaataagt tagaatatgt aagtgagtac cagatatacc
    15961 aagacatcgt caccatctaa ggtatattca aaatacaaaa gttgaccaac tagatttctg
    16021 aatatcctta tatatccatt cttaaaattg gtttaaatag cgtagtcttt taaactagtt
    16081 ttgagaatcc aaaaaatctt cctacatatg taagaagatt ttttagttca gaatgattag
    16141 atttagctaa tggataccta tcctacccac tcaccgttag cattgactcg atagccatcg
    16201 ggtgtagtcg tgtttactaa taaatctcct gaattatagg tatagtacca tttaccagaa
    16261 actgtaa
//
LOCUS       DAVEHY010000047        14992 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVEHY010000047 DAVEHY010000000
VERSION     DAVEHY010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14992
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.047"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            167..823
                     /locus_tag="VUZ44_001914"
     CDS             167..823
                     /locus_tag="VUZ44_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU0320776.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            813..1136
                     /locus_tag="VUZ44_001915"
     CDS             813..1136
                     /locus_tag="VUZ44_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU0320777.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1240..2070
                     /locus_tag="VUZ44_001916"
     CDS             1240..2070
                     /locus_tag="VUZ44_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU0320778.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2224..3078
                     /locus_tag="VUZ44_001917"
     CDS             2224..3078
                     /locus_tag="VUZ44_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU0320779.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3178..4551
                     /locus_tag="VUZ44_001918"
     CDS             3178..4551
                     /locus_tag="VUZ44_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU0320780.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4544..5605
                     /locus_tag="VUZ44_001919"
     CDS             4544..5605
                     /locus_tag="VUZ44_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU0320781.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5607..6299
                     /locus_tag="VUZ44_001920"
     CDS             5607..6299
                     /locus_tag="VUZ44_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320782.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6329..6898)
                     /locus_tag="VUZ44_001921"
     CDS             complement(6329..6898)
                     /locus_tag="VUZ44_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU0320783.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7033..7647
                     /locus_tag="VUZ44_001922"
     CDS             7033..7647
                     /locus_tag="VUZ44_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU0320784.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLVGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7649..9295
                     /locus_tag="VUZ44_001923"
     CDS             7649..9295
                     /locus_tag="VUZ44_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU0320785.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9307..10593
                     /locus_tag="VUZ44_001924"
     CDS             9307..10593
                     /locus_tag="VUZ44_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320786.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10645..11178
                     /locus_tag="VUZ44_001925"
     CDS             10645..11178
                     /locus_tag="VUZ44_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320787.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11256..11726
                     /gene="nrdI"
                     /locus_tag="VUZ44_001926"
     CDS             11256..11726
                     /gene="nrdI"
                     /locus_tag="VUZ44_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU0320788.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12019..13281)
                     /locus_tag="VUZ44_001927"
     CDS             complement(12019..13281)
                     /locus_tag="VUZ44_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU0320789.1"
                     /translation="MSQAITLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13591..14049)
                     /locus_tag="VUZ44_001928"
     CDS             complement(13591..14049)
                     /locus_tag="VUZ44_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU0320790.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14046..14486)
                     /locus_tag="VUZ44_001929"
     CDS             complement(14046..14486)
                     /locus_tag="VUZ44_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320791.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
BASE COUNT         4404 a         2766 c         3446 g         4376 t
ORIGIN      
        1 gtgttttgag ctgacttcat cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
       61 tgaggctagt ttcctagttt gctctttgat tttcattgag tattattaag acaatatgag
      121 gagaaagatg aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct
      181 tggctatgtc agtatcggcc tggcctgtgg gactatcggt gcgccctatg tgacacctgt
      241 tgagatgggc ttgatgagtc tctttgttta tgctgggagt gcccagtttg ccatgttggc
      301 actgattgtg gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt
      361 gcgtctcttt ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta
      421 caatatcggt atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt
      481 ggcccataca gacaaggtaa atcctatgtg gatgcacgga aacaatctta acagctatgt
      541 ggcttggttt gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga
      601 aatctttggc ttggattttg ccctggttgg gatgtttatt ggtatttttg cttcgcaatt
      661 tcagattatg caaagacgga ttcctgtccg caatctgctc attatcctag cagttgttgc
      721 ggtgtccttc tttttgctct tgacagtggt gtctcagtca ctagctgttc tgtttgcgac
      781 gctacttggt tgtagcatgg gggtggtttt agatggtcag taagtatctt ttattagcag
      841 ttattttctc tggcttggtg acttggattc tccgtatgat tcccttcatc ttagtcaagt
      901 ataagggctt gcctgcaatc gttgagcgtt ttttgaagtt cttgcccgtt tccattatct
      961 ttgccttgat tctttcaagc gtagtgacag gtaaggttgg gagccttcct caaattaaat
     1021 ggctagactt cttagccgtc tttccaacag cttgggtagc ctttcgctac cgcaatctag
     1081 tcggaacagt tctctttgga gtggtcttga ttgccatctt gcgtttggtc ttttaaatta
     1141 cccataaaaa aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc
     1201 tgttaagatt ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac
     1261 tcatctcttg ctgccctagg acttgttgct gcaggtgtgc ttgcggcttg ctcagggggt
     1321 gctaagaaag aaggagaagc agctagcaag aaagaaatca tcgttgcaac caatggatca
     1381 ccaaggccat ttatctatga agaaaatggc gaattgactg gttacgagat tgaagtcgtt
     1441 cgcgctatct ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca
     1501 ggtgtctttg ctggtcttga cgctgaccgt tacaatatgg ctgtcaacaa tcttagctac
     1561 actaaagaac gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc
     1621 cttgtcgtga agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg
     1681 acggaagtcg ttcaagccac tacatcagct aagcagttag aagcatacaa cgctgaacac
     1741 acggacaacc caactatcct taactatact aaggcagatt tccaacaaat catggtacgt
     1801 ttgagcgatg gacaatttga ctataagatt tttgataaaa tcggtgttga aacagttatc
     1861 aagaaccaag gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac
     1921 gtttacccac ttcttgctca aggtcaagat gagttgaaat catttgtaga caaacgcatt
     1981 aaagaactct acaaagacgg aacgcttgaa aaattgtcta aacaattctt cggagatact
     2041 tatctaccag cagaggctga tattaaataa tttcttgaaa tcatccattc tgagtaagat
     2101 gggtgatttc tcagttttta gggatatagt tttaaactat atatctgatt atctaataac
     2161 aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga
     2221 atcatgaaaa tcaaaaaatg gcttggccta gtagcccttg ctacagtcgc aggtttggct
     2281 cttgcagctt gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca
     2341 actgttaacc gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa
     2401 aaagacggaa ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca
     2461 actgctgatg gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg
     2521 aacaaagaaa acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc
     2581 ctttactcag gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca
     2641 aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt
     2701 caatcagctg gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac
     2761 atcaaagaaa atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt
     2821 tcattgtcat cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg
     2881 gactacaaga aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac
     2941 atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta
     3001 atcgcagctt accacacaga tgacgtgaaa aaagttatcg aagaatcatc agacggtttg
     3061 gatcaaccag tttggtaata agaaacaggg aggtgggaga gagaattcca cctcttgctt
     3121 ttgtatagag cacggagtgt aaagaagact attcgttcat agaaaggtag agagaatatg
     3181 gtttttccta gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agcccagcat
     3241 tattttgagg ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga
     3301 ctcaaggaag tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag
     3361 attgatgaga gctatacagc gccctttgtc atggcacatt tcaagagttc gcgtccagat
     3421 gccaagacct tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc
     3481 tggacagagg atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggagtt
     3541 gatgacgaca agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac
     3601 catgatgatt tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca
     3661 acagacctag ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg
     3721 gtctgggaac aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag
     3781 gggattgtga cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat
     3841 ggtggtgttg tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct
     3901 gcggatggcc gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga
     3961 gaaatggcct tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat
     4021 ggattggagt tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc
     4081 gagccagcgc ttaatatcga aggaatccag tctggttatc aaggtcaggg tgtgaagact
     4141 attttacctg cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg
     4201 catgatgttc tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa
     4261 ttatactata ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc
     4321 aatgtgatcg agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca
     4381 gcggggacag gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc
     4441 ggtctaggaa atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat
     4501 tattacaccc atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat
     4561 caagttagat cagatcgatg tgacttttca ccaaaagaag agaaccatca cagcggttaa
     4621 ggatgtgacc attcacatcc aagaagggga tatctacgga atcgttggat attctggagc
     4681 agggaaatca acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat
     4741 taccattgac gacgatgtga tttttgatgg taaggtcacc ttgacggcag agcagttgcg
     4801 tcgtaaacgt caagatatcg ggatgatttt ccagcatttt aacctgatga gtcaaaagac
     4861 agcagaggag aatgtagcct ttgcccttaa acactctgga ctcagcaagg aagaaaagaa
     4921 ggctaaagta gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc
     4981 ttcacaatta tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga
     5041 tccaaaaatc ttgatttcag acgagtcaac ttctgccctt gaccctaaga caaccaagca
     5101 gattttggcc ttgttgcaag atttgaacca aaaattaggc ttgactgttg tcttgattac
     5161 gcatgaaatg cagattgtca aagacattgc caaccgtgtt gcagttatgc aggatgggca
     5221 tttgattgaa gagggtagtg tgcttgaaat cttctcaaac cctaaacaac ctttgactca
     5281 agactttatc tcaacagcta caggtattga cgaagccatg gtcaaaatcg agaagcaaga
     5341 aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc
     5401 aacagacgag ccacttttga atgaattgta caagcattac caagtaatgg ctaatattct
     5461 ctatgggaat atcgaaattc tcgatggtac tcctgttgga gaattggtgg tggttttgtc
     5521 aggtgaaaaa gcagcgttgg caggtgccca agaagccatt cgtcaagcag gtgtacaact
     5581 aaaagtattg aagggagtac agtaagatgg aatcattgat tcaaacctat ttaccaaatg
     5641 tctataaaat gggttgggct ggtcaggcag gctggggaac ggctatctac ttaactcttt
     5701 atatgacagt tctttccttc attatcggag gcttcttggg gctagtggca ggtctctttc
     5761 tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca
     5821 aaattacctc aatttttcgt gcggttccct ttatcatcct cttggcaatc ttgtcaccac
     5881 tttctcactt gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt
     5941 ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg
     6001 gtgtcattga ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc
     6061 tatcagaagg tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg
     6121 gggaaacagc tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt
     6181 atggatttaa ccgctacaat cacgatgtga ccatcttggc aaccatcatt atcattttga
     6241 ttatctttgc aatccaattc ttgggagatt tcttgactaa gaaattgagc cataaataaa
     6301 aaagagccgc gtggctcttt ttaactgatc agattttctg tgcaaatttt ttactcaagg
     6361 cttgtccaat caaggcaccc actagggctc cgatgacaat acttgcgata aatagaagga
     6421 cagttccagg gtttggagcg accatgatgc ggtcgatata ttcttgggat tttcctcttg
     6481 ccagaagagt agccatatag gctttgggcg caatccacat aagcaagatt ggtcctgttg
     6541 tactaaaggc gaaaataatg aaagaaagga agttctttgt tttgtccttg tattttccta
     6601 aatgagctac ttcatctgct aggaggccac agataattcc aggaaggaag gaaccagcac
     6661 cgtgtttagt tcccaagaaa aagagggcaa tgacaaggcc gatagtggta atggctccaa
     6721 agcgcggaac ttttgcgact aggatcatat agacgctacc gccgacaagg gcagtaaagg
     6781 caggcgcata aaacatgttt ccagtttggt caaagagatt gcccaaaagg acaccaatcc
     6841 ccatgcagag gaagtaaaga actgcaaaaa gcagtgtagt taagatagat ttcttcatga
     6901 attgtctcct gataattttt tcacaattct cattgtacca cggtttggtg ggattgtaaa
     6961 tggatactag aagtttttga aaacgcttga aatatgatat aatggtttca tagttatttt
     7021 taggggaata tcatgggtag atttttagac tttgtcttta atcgtttctt tttagggatg
     7081 attgcgacag ccttcttttg gctattaact ttagtaggag ggattatcct tggtctagcg
     7141 ccagctagtg ccaccttgat gagcttatat gcagaacatg gttatagctt tcgggaatac
     7201 agtttgaagg aggcttggtc tctttacaag caaaattttg tctcaagcaa cctgattttc
     7261 tatagctttt taggtgtggg tctagttttg acctatggtt tgtatctctt ggtgcaattg
     7321 cctcatcaga ccattgttca tttgattgcg acccttttga atgtcctagt agttgccctg
     7381 atctttttgg cttatacagt atctttaaaa ttacaagttt attttgcctt gtcctatcga
     7441 aatagtctca aattatcctt gattggcatc tttatgagtc tagcagctgt ggccaagatt
     7501 ctccttggga ctgtgctact tgtagcaatt ggttactata tgcctgccct gctatttttt
     7561 gtaggaattg ggatgtggca tttctttatc agtgatatgt tggaacctgt ctatgaaatc
     7621 atccatgaaa aattggcgac aaaatagaat gaagcacttt tggctacata cgcttctaag
     7681 aacctatagt tcagtgatga tcattatcat tgcgagtttt gcaatcttac tctcttacgc
     7741 tgactgggat tcacgtgaaa aggaagccca gagagtagcc cagcgtgtaa ctgctagaac
     7801 agtgagtgaa attgaatatt accatagaga gtcaacccag atagctcagg ctttagttga
     7861 aaaccaagct cgtattgagg gaatctataa atactttagc cttagcatgc cagactattt
     7921 ttactggcaa ttagagcgga aagcttcgcc ttatatatca gtctctctgt atgaaaatgt
     7981 tgatgacctc tatgttcgaa atgattttgt aactggggtg gccattgctt ttcaagatta
     8041 caaggaagtc tatgtttcta ctaaagacaa acgtagtgga gaaaaaatca gggctgagga
     8101 tttcaaacca gcaggaaata gttttgccat tccagtgtca gatccagtgt cagatcaaga
     8161 cttaggagtg atttacatct ccttggatcc tgctgtttta taccatgcca ttgataatac
     8221 tagaggtcat actccgatgg cagtaacagt gacctcacct tttgatacgg agatttttca
     8281 tattggtgag acagttgata aggagagtga aaattggcta gttggcttaa cttctcatgg
     8341 ttatcaggtt caggtggcag ttcccaaaaa ctttgtttta caaggaacgg tgaccagctc
     8401 tgctttgatt gtgggcttga gccttctctt tattgtcatt ctttatctga ctttgaggca
     8461 gacctttgct aattatcaaa agcaggtagt ggatttggtg gattccatcc aagctattgc
     8521 ccaaggacaa gaaggtcttc gcattgatac gcttgaaaag gatcaggaat tgctcctaat
     8581 cgcggagacg accaatgata tgttggatcg attggaaaag aatatccatg atatttacca
     8641 gttagaactc agtcaaaaag atgccaatat gcgggccttg caggcgcaaa tcaaccctca
     8701 cttcatgtat aatacgctgg agttcttgcg catgtacgca gtcatgcaga gtcaagatga
     8761 gttggcagat atcatttatg aattcagtag tctcttgcgt aacaatattt ccgacgaaag
     8821 agagaccctc ctcaaacagg aattagaatt ttgccgtaaa tacagctatc tctgcatggt
     8881 tcgctatccc aagtccattg cctatggttt caagatagat ccagagttag agaatatgaa
     8941 gattcccaag tttaccttgc aaccgctggt agaaaactat ttcgcgcatg gtgttgacca
     9001 caggcggaca gataatgtga ttagcatcaa ggctcttaaa caggatggtt ttgtggaaat
     9061 tttggtggtc gataatggta gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa
     9121 attaagtcag agatattttg aacaccaagc cagctacagt gatcaaaggc agtctatcgg
     9181 gattgtcaat gtacacgagc gttttgtgct ctattttgga gaccgctatg ccattacgat
     9241 agagtctgca gagcaagccg gtgttcagta tcgtattaca attcaagatg agtagaaagg
     9301 gagaaaatgt ataaagtatt attagtagat gatgagtaca tggtgacaga aggtctgaag
     9361 cgtttgattc cctttgataa gtgggatatg gaggtcgtcg caacagccag tcatgccgat
     9421 gaagctctag aatatgttca ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg
     9481 ccagacaaaa cagggcttga tatgattcgg gagatgaaag agatcttacc agatgctgcc
     9541 tatatcctgc tctcaggtta tcaggagttt gattatgtaa aaagagcaat gaaccttagt
     9601 gtggtggact atttggtcaa gcctgttgat aaggtagagc tgggaaatct gctggagaag
     9661 attgcaggtc agctcggcga gagagggaag aaaagtcaga ctcttagtca agaattagac
     9721 gaggctggat ttgttagtta tttaggggat aaggagaatt ggtggatagg tctatccaag
     9781 gaaaaacaag gttccttcgc cattccctac tatgtcttgg gccaagactg gcagattttc
     9841 atttctgacc aacccctaga tggtttagtc gttacacctt ttgaagctcc ttatcaagaa
     9901 cactttgaac gctggaagct gaatgctgag aaaaccctct tttacggttc tgtaaatctg
     9961 cagcagtctg agagtctctt tgcctattac gaaccgattt atagggttat cattcaggga
    10021 aatctcaatc aaatcgtaga agagttaaat ctcttggaga aggtagttct tgaaaatacg
    10081 ccgcgtgttc cgattactaa acagcttttt attcagtttg tcatggatgt tttccattta
    10141 tttgaacatc tcaaagctga tgacctgaca gacatcgtca aaaccattca tgctattcaa
    10201 tccttcgatg aattggttcc ttatatcaag gaaactctga gcagcttttt cggtcaatac
    10261 cgtatgaatg aaaatgtggt cagtgtgctg gaagtcattg gtcgtgatta ccaaaaagag
    10321 ctttccctca aggatatcag taaggctctc tttatcaatc ctgtctatct agggcagttg
    10381 attaagcgtg aaaccgattc gacttttgca gagttactaa acaaacaacg tattaaggct
    10441 gcccaacaac ttttgctttc aactagtgac agcatcgaag atatttgtta tgctgttggt
    10501 tacagtaacc ttggatattt ctataaagtt tttcgaaaat tgtgcggaaa atcgccaaaa
    10561 gcctaccgaa aacaggtaga aactatacta taagatttgt attcctttac aaaaggtgct
    10621 ataatattat caggaggttc tatcatgaaa aagaaaccaa tttatctatg ggtcttgcta
    10681 atcttgtctg cccttatttc agttccgtct ctgtttggaa ttgtgagtcc cttgcctagt
    10741 aaagaagccc ttcgtgctgc tcagaaacaa gttgcagggg tcaatgctca gcaattagaa
    10801 gaccagctta attataccta tagagtagca gaagcatctc attctatttt taatgttgct
    10861 ttgattgtgc tatctactat tttagtggtc gtagcgattg tcttccttgt tcgtaaaaat
    10921 ttgcaatatg caaactatac ttacgttggt tatgttttgt tagctattat tggttcgatt
    10981 tatggctatg ttggtttaca agacgctgtg cagttggttc aagatgagag catgcgtttg
    11041 acagtgagta ttggttcaaa agctgttagc attttctata tcgtcatcaa tgttctcttc
    11101 ctagcccttg tcttctataa gatgtggcga caacagaaag ccttggcaga agaagaggaa
    11161 acagaagagc ttacctaagt attgacaaaa aagaactatc aagatacaat cttggtagtt
    11221 gttttttgat tatagataaa atcatggagg tacatatgaa gacaatttct ttagtttata
    11281 ttagtttgag tggcaacact gaaagttttg tgacgcgctt gaaagactat ctcttgtccc
    11341 agtacaaagg gattgaggtt caaaagattc atatcaagga tttggtcaag gaaggcaaaa
    11401 atttctatga aatggaccat ccctatgtcg cttttttgcc gacctatctc gaaggtggga
    11461 atggcgtgga taacggagat gttgagattt tgacgacacc ggtgggagat tttattgcct
    11521 atggtaacaa tgctagtaag tgttttggtg tggttgggtc aggaaatcgt aactttaata
    11581 accaatactg cctaacagcc aagcaataca gtcaacgctt tggcttccct gtattggctg
    11641 actttgaaat gcgaggcatg ctggaagata tcaaacatgt cgcagctatt atcgcagatt
    11701 tgtatgagtt ggaaaaggag aattaatact caatgaaaat caaagagcaa actaggaagc
    11761 tagtcgcagg ttgctcaaag cacagctttg aggttgcaga tagagctgac gtggtttgaa
    11821 gagattctcg aatagtataa agttcttata agaggtggtt gaagttgttc aactgttttt
    11881 tgagtataaa cagtctttaa gaacgtaaaa aagcataagt tcaggtcttc aaaaccttgt
    11941 tcttatgctt tttatcatag aaatatttgc tgaattttct cttgaaatga aaccttatct
    12001 tcatctcgcg cttgtccctt accctgcttt tccgattgcg agtgcgtaga taaagaagat
    12061 ggcgaagcca aagaggaaaa tcaatcccgc aatggcaagg tgtttgagcc aagaaggaag
    12121 atttttgttt tcacgcgtta ccaaggcgta attcaaaaga gcaaagaaag gtgttgtcag
    12181 gaaagagcca atcatggcaa agcggagcat ggttgaaacc tgaccagcga agaacttgat
    12241 aatgacgata ccgatgatag cagtgatggt catccagatg ttcaaagatt tacgattgtc
    12301 ctctttttga ctgattagca gtcggagaga ttcctgatta acgcgagaat agccatcgat
    12361 aacagttata actgttccaa agatacagag gaaggcaata aaggtaatca agtaacggga
    12421 ccattcgcca agaacagagg catacatgcc cacgaattga gagatgtatt tggctgaagc
    12481 agcttcaacc gcctgccctg taggatactg aatcagtgct cccagtgcca caaagaagac
    12541 ggctaggata gctgttccaa tataaccagt gttaaagtca aacagagcgt cttctgtgtt
    12601 aaagttgacg gtctttctct tttcagctga ccaaagtgaa ttgatggctg aaatttcaat
    12661 aggagccggc atccatccta ggagggagac gatgaagggc agagctgcca tttgccaagg
    12721 tgtcttctcg acaaaatcag aactgtattc tggatgcttg accgccgcaa tgataactgc
    12781 aagaacagtc gcaatggtta aggcagacat aatccatttg accatgccgt ctaaaagttt
    12841 gtagcctcca aagagtagca tagcccaaat gattgcaacg agaatgaggg accactgagt
    12901 aatgctaagt ccaatcattg ggaaagcact ggcgatgata gctgagcaca gaatggcaac
    12961 accagccgtg ttgaccatag ccgaaaagac attgaggata aagaaaatcc agagatagag
    13021 ttttcctttt tcggcataac cttcaaccaa agtctttcca gtatcagctg tgtattcagc
    13081 accaaaacgg aaaaatggat atttaaagac attggctaag atgaccaaga gaagtagaga
    13141 ccaaccgtaa gaaccgccag cttgagttga ggatacaatg tgggaacctc caacagcggc
    13201 agttgccatt aggattccag gtcccattgc ttttagcttg cttgcccagg ttgattgatt
    13261 taaggtaata gcttgcgaca tgataaatac tcctttttga attttcagaa taatctgtat
    13321 atgtaatcta tattctacaa aaaattttgg aaaaatgcaa gaatattttg aaaaaagata
    13381 gaaaatttac aaagaaaatc tgaaataatt gttatgatat agcagattga aactagaata
    13441 gtacaccttt gcttctaaaa cattgttaga aatctatttg actgtcctga tcgatttatc
    13501 ctgttcttat ttcatttcac tatagtaagg tgcagcagga taaagaaaaa ccgagaagtt
    13561 tctttctcgg atttgcttat tatgaggttc ctattttcta tgctccaaga gttgattgat
    13621 gtgatctact tttttagcct ctcttttata gagaatagcc cagatgatga gatagacaat
    13681 cgcaaactcg ataatgagct ggaggtagaa aatccagtgg aaagggaacc aaccagcaag
    13741 agttgctagt gggacaaagc cagccagcat aaggaagaaa tgagtcagag tggcacgaag
    13801 catgctccag tcacggctaa ataagcggtt gccaaagttg aagagcatac cgatggttgc
    13861 ccagataagt gtgcagtaga gcaagaccag ggcaccgtga acctgatgct gatccatcac
    13921 ttggccgatg agagagtagg gatttagtgg tgcgtaggta tttggtgcat aaatgagtga
    13981 aaagaggata gagaggatga ggccgataag aacaccggta gctgcatcgt gaaatacttg
    14041 ttttttcata gttctaattt ctccttgatg gtttttagat aacggcgtga agagtaggtg
    14101 aagctttcgt ttttcaagaa aatttctacc agaccgtttg gcgtgagctt gaggtgagag
    14161 atggaatcga tattgatgat ttctgattgg gaaatttgga taaaattggt tggcaagagt
    14221 ttaagaacct gatagagtcg caaatcaatg ctgtaggtct gactcgcggt ttctgctaga
    14281 accttccgat tctcgatata gaagcgctga atcttgccaa tctcaactag atagacctga
    14341 tcatcgattt ttcctttgat tttttctctt tggtccagat tttctgcgaa ctcgatgact
    14401 ttctggactt tttcggtttc ttgaggtgct tggacaatca gcttttcctc ctcgtaagtc
    14461 tcactaatct gtagttctac tttcatagtt ttctctcctt ttcagttata caaggttgtg
    14521 atcacttcct gtatatcctt attaaacact attttatagc ccatggcaag gaaccttgtc
    14581 tatgtggagg gattgggctc ctatgtggtg gagcttttct gttctttctg aaatatggta
    14641 taatagcact aatcaatttc taggaaaata gatacggaaa ggggctgaaa gaactagggg
    14701 aacagttgga attagaaagt gataggtatg aaaagtggcg ttgaagctga ataagtttat
    14761 aaagcgtttg aatgaagaaa tggaaagtaa ataagttgac gatgaattac aaaatagatt
    14821 ttatctacaa tttgtatctt tcaaatcatt gatttgaatt ttagatttaa tcatgttaca
    14881 attaaaactg aaatcaaata gaagaggaaa atgcaaacgt gggcacacta ttagcaacaa
    14941 gattaaaaaa tagacggaaa gaattaaaaa tgtctcagcg agaactagct ga
//
LOCUS       DAVEHY010000048        13292 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVEHY010000048 DAVEHY010000000
VERSION     DAVEHY010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.048"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(64..1635)
                     /gene="ffh"
                     /locus_tag="VUZ44_001930"
     CDS             complement(64..1635)
                     /gene="ffh"
                     /locus_tag="VUZ44_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU0320792.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(1647..1979)
                     /locus_tag="VUZ44_001931"
     CDS             complement(1647..1979)
                     /locus_tag="VUZ44_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU0320793.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(2070..2447)
                     /locus_tag="VUZ44_001932"
     CDS             complement(2070..2447)
                     /locus_tag="VUZ44_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU0320794.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2519..3823
                     /locus_tag="VUZ44_001933"
     CDS             2519..3823
                     /locus_tag="VUZ44_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU0320795.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            3836..4642
                     /gene="yidA"
                     /locus_tag="VUZ44_001934"
     CDS             3836..4642
                     /gene="yidA"
                     /locus_tag="VUZ44_001934"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU0320796.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            4685..5683
                     /locus_tag="VUZ44_001935"
     CDS             4685..5683
                     /locus_tag="VUZ44_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HEU0320797.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNDLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5849..5920)
                     /locus_tag="VUZ44_001936"
     tRNA            complement(5849..5920)
                     /locus_tag="VUZ44_001936"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5885..5887),aa:Arg,seq:cct)
     gene            complement(5962..6309)
                     /gene="rplS"
                     /locus_tag="VUZ44_001937"
     CDS             complement(5962..6309)
                     /gene="rplS"
                     /locus_tag="VUZ44_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU0320798.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(6428..6757)
                     /gene="crcB"
                     /locus_tag="VUZ44_001938"
     CDS             complement(6428..6757)
                     /gene="crcB"
                     /locus_tag="VUZ44_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU0320799.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(6751..7125)
                     /gene="crcB"
                     /locus_tag="VUZ44_001939"
     CDS             complement(6751..7125)
                     /gene="crcB"
                     /locus_tag="VUZ44_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU0320800.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(7122..7388)
                     /locus_tag="VUZ44_001940"
     CDS             complement(7122..7388)
                     /locus_tag="VUZ44_001940"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU0320801.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(7504..7947)
                     /locus_tag="VUZ44_001941"
     CDS             complement(7504..7947)
                     /locus_tag="VUZ44_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU0320802.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            8051..8986
                     /locus_tag="VUZ44_001942"
     CDS             8051..8986
                     /locus_tag="VUZ44_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU0320803.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            9040..9324
                     /locus_tag="VUZ44_001943"
     CDS             9040..9324
                     /locus_tag="VUZ44_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU0320804.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(9381..9599)
                     /locus_tag="VUZ44_001944"
     CDS             complement(9381..9599)
                     /locus_tag="VUZ44_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320805.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(9596..10347)
                     /locus_tag="VUZ44_001945"
                     /pseudo
     CDS             complement(9596..10347)
                     /locus_tag="VUZ44_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            10684..12030
                     /gene="gdhA"
                     /locus_tag="VUZ44_001946"
     CDS             10684..12030
                     /gene="gdhA"
                     /locus_tag="VUZ44_001946"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU0320806.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(12536..12706)
                     /locus_tag="VUZ44_001947"
     CDS             complement(12536..12706)
                     /locus_tag="VUZ44_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320807.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(12719..>13292)
                     /locus_tag="VUZ44_001948"
     CDS             complement(12719..>13292)
                     /locus_tag="VUZ44_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU0320808.1"
                     /translation="KIPSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLN
                     RSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIA
                     LARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIVAHRLSTIKDADVIFV
                     MKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT         4119 a         2845 c         2301 g         4027 t
ORIGIN      
        1 gttttatcat agaaattttt actttatttt ctcatcaaat gagatttgca tcaatctctt
       61 gtcttacttg cgtttcttct tcgctttctt cattttgtta gccatacgtt tcatggactg
      121 tttcatggca aattcaccaa ttttaccttt caaaccgcca ccaaacatct ggctcatatc
      181 tggcattcct gctcctccga gagctgataa gtcaggcata ccgccttgtc ccatcattcc
      241 ttcaagggca gacatatcca ttcctcccat atttggcata tttttaggaa ggttatttgg
      301 attaatcccc atttgcttca tcattttatt catatcccca gacataacac cctgcatgag
      361 ctgtttagcc tggttaaagt ccttgatgaa tttattgact tcgacgaatg tatttccaga
      421 accagcagca atacgacggc gacggcttgg atttaacaaa tctggatttt cacgttcttc
      481 aggtgtcatc gaagacacaa tcgcacgttt acgagcaatc tggcgttcat ccaccttcat
      541 gttttgaagt gctggattgt tggccatacc tggaatcatc ttgagcaagt cttccatcgg
      601 ccccatattt tgcacctgat ctaattgatc gatgaaatca ttaaaatcaa aggtgttttc
      661 gcgcatcttc tcagccattt caagggcttt ttgttcatcg tattcctgag aagctttctc
      721 aatcaaagtg agcatatccc ccatgccaag gatacggcta gacatgcggt ctgggtggaa
      781 ggtttcaatg tccgtaatct tttcacctgt accagtgaac ttgattggtt ttccagtaat
      841 gtgacgaaca gacagagcag caccaccacg agtatcgcca tcaatcttgg taaggatgac
      901 cccagtcact tccaactgag cattaaactc acgcgcaaca ttggctgctt cctgaccaat
      961 catagcatca acgacaagca agatttcatt tggttgagcc aatgctttca catcacgaag
     1021 ctcattcatg aggagctcat caatctgcaa acgacccgca gtatcaatca agacatagtc
     1081 gttatgatta gtttgagctt gctccaaacc ttgacgtaca atctcaacag ctggaacctc
     1141 tgtcccaaga gcgaaaaccg gcacatcaat ctgttgtccc agtgtcttca gctgatcaat
     1201 ggcagcagga cggtaaatat ccgccgcaat catcaaagga cgggcatttt cttccttctt
     1261 gagtttgtta gccagcttac ctgcaaaagt tgttttacca gctccctgca aaccaaccat
     1321 catgatgatt gtaggaatct taggtgactt gataatttct gccgtatcag aacctaaaac
     1381 agctgtcagt tcctcatcaa cgattttaat aatctgttgc gcaggattaa gtgtatcaat
     1441 gacctcatgc ccgactgcac gctcacgaac tttcttgata aagtccttta caacaggcaa
     1501 ggcaacgtcg gcctcgagca aggccaagcg aatttctttg gttgcctctt ggacatcaga
     1561 ttcagagatt tttccttttt tacgtagact tttaaagacg ttctgcaaac gttctgttaa
     1621 actttcaaat gccatttttc ttcctcttat tctctattat caatgcttgt taaaatttct
     1681 atctgctcct gcagaaagtt atccttggga tagcgctcca aaatctgatc aaaaatctga
     1741 ctgcggacaa tatagtccga gtacatgtgc aatttcatct cataatcttc cagaatcttt
     1801 tctgttcgct tgatattgtc atagacagcc tgacgactga caccgaactc ctcggcaatt
     1861 tcagcaaggc tgtaatcatc agcgtagtag agctcgatat aattcatttg cttatctgtc
     1921 aaaagcgccg cataaaattc aaagagcgca ttcatacgat tggttttttc gatttccata
     1981 acttttatta taccaaaaat tagcctaatc taccacacta ggaagccgat ccaagaagat
     2041 agatagctaa atttgaaaaa gacataagcc tagccccaag taatttccaa ttgatagctg
     2101 gcaaagggat gtccctcttg attttgtagt tgataatcta gttcaatctt ttgcccatcc
     2161 acttgataac gattcgtttg gataataaac tcctgcatac ccataggtgt gggaatatag
     2221 gctaaactat cactatcctt tagaaagcgc ataatggtct tgggattgga aaatcgactc
     2281 atcacaagtt cttgaccatg aaatttaatc actacttttt ccttttcctc attatagaaa
     2341 agcaggtagc tataatctcc tttttcatgc acttccacat cataaagctg gtcaattact
     2401 tccaactgct catcaaactg aattgtattt cgcatccgaa tcttcacatc aggccctctt
     2461 tcttgtctct tgtcctacta ttttaccaaa aagagcagga ttttgctata atggtcatat
     2521 gaacgaaaaa gtattccgtg accctgttca caactacatc catgtcaata atcaaatcat
     2581 ctatgacttg attaatacaa aagaatttca gcgtttgcgc cggatcaaac aactgggaac
     2641 ttccagttat accttccacg gtggagaaca cagtcgcttc tctcactgtc taggagtcta
     2701 tgaaattgca cgacgcatca cagagatttt cgaagaaaaa tatcctgagg aatggaatcc
     2761 tgccgagtct ctcttgacca tgaccgctgc tctcctacac gaccttgggc atggtgccta
     2821 ctcccatact tttgaaaatc tctttgatac agaccatgaa gccattactc aggagattat
     2881 tcaaaatcct gagacagaga ttcaccaagt cctgctacaa gtggcacctg atttcccaga
     2941 aaaggtggcc agtgtcattg accataccta tcctaataag caggtcgtgc agctcatttc
     3001 tagtcagatt gacgcagatc gcatggacta tctcttgcgc gactcctatt ttacaggagc
     3061 atcctatggg gaatttgacc tgactcgaat cctccgagtc attcgtccta tcgaaaatgg
     3121 tatcgccttt cagcgcaatg gcatgcacgc catcgaagac tacgtcctca gtcgctacca
     3181 gatgtacatg caggtttatt tccaccccgc aacacgcgcc atggaagttc tcctacagaa
     3241 tcttctcaaa cgcgccaagg aactctatcc tgaggacaag gatttctttg cccgaacttc
     3301 tccacacctc ctgcctttct tcgaaaaaaa tgtgaccttg actgactatc tggctctgga
     3361 tgatggcgtg atgaatacct acttccagct ttggatgacc agtcctgaca agattcttgc
     3421 agatttatcg catcgctttg tcaaccgcaa ggtctttaaa tccattacct tttcacaaga
     3481 agaccaagac caactcgcta gcatgagaaa attggttgag gacatcggct ttgatcccga
     3541 ctactatact gccattcata agaactttga cctcccttat gatatttacc gtcccgaatc
     3601 tgaaaatcca aggacacaga ttgagatttt acaaaaaaat ggagaactgg cagaactctc
     3661 tagcctgtcc cctatcgtcc aatcccttgc tggaagtcgc cacggagata atcgctttta
     3721 tttcccgaaa gaaatgttag accaaaacag catcttcgca agcatcaccc agcaattttt
     3781 acacttgatt gagaacgatc attttacccc aaataaaaac taaaagagga aatttatgag
     3841 tattaaacta atcgccgtcg atattgacgg aaccctagtc aacagccaaa aggaaatcac
     3901 tcctgaagtc ttttctgcca tccaagatgc caaagaagct ggtgtcaaag tcgtgattgc
     3961 aactggccgc cccatcgcag gtgttgccaa acttctggac gacttgcagt tgagagacca
     4021 aggtgactat gtggtgacct tcaatggtgc ccttgtccaa gaaactgcta ctggccatga
     4081 gattatcagc gaatccttga cctatgagga ttatctggat atggaattcc tcagtcgcaa
     4141 gctcggtgtc cacatgcatg ccattaccaa ggacggtatc tatactgcaa atcgcaatat
     4201 cggaaaatac actgtacacg aatcaaccct cgtcagcatg cctatcttct accgtacccc
     4261 tgaagaaatg gctggcaagg aaattgtcaa gtgtatgttc atcgatgaac cagaaattct
     4321 cgatgctgcg attgaaaaaa taccagccga attttacgag cactactcta tcaacaaatc
     4381 tgctcctttc tacctcgaac tccttaaaaa gaatgtagac aagggttcag ctattactca
     4441 cttggctgaa aaactcggat tgaccaaaga tgaaaccatg gcaatcggtg acgaagaaaa
     4501 tgaccgtgcc atgctggaag tcgttggaaa ccccgttgtc atggaaaatg gaaatccaga
     4561 aatcaaaaaa atcgccaaat acatcactaa aacaaatgac gaatccggcg ttgcccacgc
     4621 catccgaaca tgggtactgt aaaagtatca tttttcaata agaattgatt agcaataaaa
     4681 tccaatgaat ttttttagca aactatttaa tttaaaacaa aataatcata atagagacac
     4741 aaattctgat tgtaacaatt tttacctaaa cgatttagaa tgtggcctta ctcctgggca
     4801 actcatactc atagattgga ctcaaaaaac agggagaaat tataatttcc caagatattt
     4861 taaatactct cttcaaattg accctgaatc tacacacaat caattataca aattaggata
     4921 cttcactaaa aataagactt tatcatatct tacagtagta gaattaaaaa ctatattatc
     4981 taaacataat ttagctactt ctggaaaaaa agcagaatta attacaagaa taattaataa
     5041 tgttaacatt gacaatttag atattccgtt cgaatttaaa ctaacaaaag aagcacaaaa
     5101 tcttattatc gaacatagtg actatatcaa agcatactat gataaagaca taactatgga
     5161 agattattgt aaagaaaaaa acaatatctc ttttaaagca acttttggtg atataaaatg
     5221 gagtctctta aataaacaag ctcataggaa tactgtatca ggagattttg gatgcttatc
     5281 taacacacga aaggctcagg gaagacattt ggaacaagaa ggtaatatta aacatgcttt
     5341 aatatattac atagaatctt tgataattac tatttcagga ttagaaaaca atttttcagc
     5401 cactgattat ccagtatatt atcccgattc gatacctgac tactcactaa aacatattca
     5461 aacattaatg gaatcattat ctgatgacga ttatgatttt gcttttgatg aagcattatt
     5521 tcgcttctca attttgaatg caaatcattt tttatctaag gaagatattg actatttaag
     5581 agttaattta cctcgttcca ctgctgaaga aataaacaat tacttaaaga aatatgaatg
     5641 ttatagtcct ttaaataatt tagaacttga cgattttgaa taaattgact atacaaacat
     5701 ttatatactc gatatagtct caattttatc tgatgattgc ccaaattttt caataataaa
     5761 acgcataata ttatggagac aatcccctat attatgcgtt cttttaatat caaagacttt
     5821 ttgacaaact tcttcgatat ctaattactg ccccctgcag gaatcgaacc tgcaactact
     5881 ccttaggagg gagttgttat atccattgaa ctaagggagc tagataaaaa ctctgctgaa
     5941 aagcagagtt ttttagtcga attaacgacg gatttctttg atacgagctg ccttaccttg
     6001 aagagcacgc aagtagtaca atttcgcacg acgtacttta ccgtaacgaa caacttcgat
     6061 tttttcaaca cgtggagtgt ggattgggaa gatacgctca acacctacac cgttagagat
     6121 tttacgaact gtgtagtttt ctgagattcc agcaccttta cgtgcgataa caacaccttc
     6181 aaaaatctgg atacgttcac ggttaccttc gacaactttc gcatgtacac gaacagtgtc
     6241 accaggacgg aatgatggga tatctgtacg aagttgacct tcagtcaagc tttggattaa
     6301 tggattcatt ttattctcct atctttgtca atcttgagga atcttcctca gcggataaac
     6361 tgtatttttg tgcgtccatt acacacaaga tatagtttac caaatttcta aaaaaaagta
     6421 aagaaattta tagcaaaatt cctaaaaaaa tcgcaaccaa accacctatg taagtcaaag
     6481 tcaggtaaga ataaaagacc ttcttatcac ttagcagtct ttgaagttcg tcattcaagg
     6541 tcgaaaaagt tgttaaaccg ccacaaaatc ctgttgctag aatagcatat acttccttag
     6601 actctacatg attgtagaat actccaatta aaaaacaacc taaaagatta gctatgagcg
     6661 ttccgagtgg caatttagaa gcttgattat agcgagaaaa gaaataccgt acgagtgctc
     6721 ccaagccaca ggcgattgca agatagacga ttaccatttc ttcctcccca aatagtaagc
     6781 taaaagcagg cctccaccga tactcaaaag caaatacagt atcaaactaa gataacgccc
     6841 tgtatcaagc agcttcacag tatcaagcat taggctggaa aaagttgtta aacctccgca
     6901 aaaacccgtc cccagtgcta aaatcaagcc cttactagtc cccttataga ccagatagcc
     6961 cttgacaaga taaatcaagc agaaaattcc cagatagttg acaaagagag tgccccaagg
     7021 gaaatctgga ctggctggta accaagtgga aactaggtag cggacaagtc cgcccaacat
     7081 agcagctaga aaaatcccta gcggataaaa ttgttctttt ttcatttgat attttgatcc
     7141 tgataatcac gcgaacgttt gagtatgtcc gaaaaagtcg cgacaatagt ctcctgatag
     7201 cgcttgtcct ctacacgact tctaaccttt tcaaaaataa ctgcttctct cttagtatct
     7261 aaaatcggtt tccctgaagc cttcttataa gcgacaactc cttcaactaa gtgcattcgt
     7321 tcttctaaca gtttgacaat ttggtcgtcg atttgatcga tttcttgacg aataatatct
     7381 aaatccatac agtctcctcc tttatttgaa ttattgtatc aaaaagccat caattaggct
     7441 agtaaaatcc caactctcga taagaaaaat gcactgattg attacatcag cgcactttta
     7501 tgcttatcct actttagcag ccaattcttc tgcgaattgt tccaagcgtt caatatcttc
     7561 ttcctcggca gaaagatcaa ctttaacaca ctctgaacct ttttctgctc ctgttgacac
     7621 aaagacacgg tcaaagtcat caacagcctt acaaaattca tcgtagaagg tatctcctga
     7681 gccgaccact ccgtagattt tgccattcaa gttgagatct gctaggtctt cgtagaagtc
     7741 catcatctca tctggcaatt caccatcacc ataagtatag gtcgcaacga tagcgatgtc
     7801 tgcttccaag aagtctgaag cgtcaacagt tgtacattca tcaacatcaa catccaagcc
     7861 caagtcacgt aatttgtctg ctacaatatc tgcaatttct tcggtattac cggtcatact
     7921 ggcaaataca atttttgcta atgccatatc gtcctcctca atttatcttt ctccattata
     7981 tcacatcttt ttcattttaa aaataaaaat tcttgtgcta caatgaaatg agaaagaatt
     8041 gaggttattt atggagattt gccaacaaat tttagaaaaa attaaagaat acgacaccat
     8101 tatcattcat cgtcatatga aaccagaccc tgatgccttg ggaagtcagg tgggattgaa
     8161 agccttgcta gaacatcatt tcccagaaaa aaccatcaaa gccgtcggtt ttgatgaacc
     8221 aactcttact tggatggctg agatggatct tgttgaagat agagcctacc aaggcgcact
     8281 tgtcatcgtc tgtgatacag ctaatactgc tcgtatcgat gataagcgct atagtcaagg
     8341 tgattttctc attaagattg accaccatcc aaatgatgat gtatacggtg acctgtcttg
     8401 ggtcgatact agttcaagta gcgctagcga gatgattacc ctatttgccc aaacaaccca
     8461 actagccttg gcagatcgcg atgctgagtt gctctttgca ggaattgtcg gtgatacagg
     8521 tcgcttcctc tacccttcta ccactgcacg gactcttcgc ctggctgctt atttgagaga
     8581 acataacttt gactttgcgg ctctcactcg caaaatggac actatgagct acaaaattgc
     8641 taaactgcaa ggctacatct acgaccatct ggaagtggat gaaaatggtg ctgctcgcgt
     8701 tatcctgagt cagaaaatct tgaaacaata caatataacc gatgctgaaa ctgcggccat
     8761 tgtaggtgca cctggacgca ttgacagagt gagtctctgg ggaatttttg tcgaacaggc
     8821 tgatggccac taccgagttc gcttacgcag taaagtccat cctatcaatg aaattgccaa
     8881 ggagcatgat ggtggaggcc accctctagc aagtggtgct aattcctata gcctagaaga
     8941 aaacgaaatc atctaccaaa agttaaaaaa cttgcttaaa aactgataaa atacttgcca
     9001 aacttttcag aatctgatag actagtatag taacaatcta tggctcgcaa agagaccatg
     9061 gcagaaagga aatattgcaa aatgaaaaaa gatatccatc cagaatatcg cccagttgtc
     9121 ttcatggaca caactactgg ttaccaattc cttagcggtt caacaaaacg ctctaacgaa
     9181 acagttgagt tcgaaggcga aacttaccca ttgatccgtg tggaaatttc atcagactca
     9241 cacccattct acactggacg tcaaaagttc actcaagcag atggacgcgt ggatcgtttc
     9301 aacaaaaaat acggtctcaa ataatgataa gagaacagtt ttggctgttc ttttttgttt
     9361 cttgaaatca actgctgttt tcatgttcca gactcatctg taggttcgat ttccatgcta
     9421 ctaggcagga aggaaatagc tgtttcaaca cgtccataat gagctatact attgtcacga
     9481 accacacttt cattgatggt ccaagtggaa ttcattttct taaaagcttc tcggactttt
     9541 tccaaatctt tggaggcaat ggcctgctct aaggtttcaa aacgaggact tatactcatc
     9601 tgctttcaaa aagcattcta gtccatctcc gattaccgat ggactttatc acctccttct
     9661 ccagtccttg tatgacatct tgaagttgat tcatgacatc ttccaaagtt cgaaaggctt
     9721 tattcttaaa tccacgttta cgaatctctt tccacacttg ttcaatgggt tcatctctgg
     9781 tgtgtatgga ggaataaagg taaaatcaat attagtcgga atatttaagg tacttgattt
     9841 atgccatata gcattgtcca taacgagtaa aaggataagc ttgtgaaagc tcttctaaaa
     9901 aggcgttcat ccacactcct ttttataaac ctgaaataag gcatcaattg taacaaattc
     9961 tcctgcctct gtagccttca aatgacgggc aagaaaggct ttctcttcct caactgtcat
    10021 atatgcatgg ttacgaccac cacgtgtttc ttgaaggaga gagtcgagtc cgaactcctc
    10081 atattttttt acgtttcgcc aaatcgttgt ttgattacag tctaaaagct ctataatctc
    10141 tttataagat ttgcccatca gacgaaatat agtagattga aactagaata gtacacctct
    10201 acttctaaaa cattgttaga aatcgatttg tcctgttcta gtttcatttt actatagaac
    10261 gatttgaagg cgtttataat atttagctgt acgagagtct tttaaaagtg ttttgatggt
    10321 ttggatttct tctttagttg atttcatatt actattatat aatgcttttt gattttagtc
    10381 tggtataaat attgctttcc tccaaaatgg tcatagtttt actggcaaat ctaacatatc
    10441 acggataaat taacaagtga tttctgaatt gctaaacatt ttcttttctt atagcatact
    10501 ttaagatttt gtctttgaga aagatatttc caagaaaaac gttcgttttt ttatctattt
    10561 tcaaaaaaac caaaaaactg aattgaaaga atttttagaa aatttctgtt ttttctttac
    10621 agtgaaaaaa aattctgcta taatgtctta tgtaataaaa tatgacaata aaaggagaac
    10681 gatatgacat ctgctaaaga atatatccaa agcgtgtttg aaactgtgaa agctcgtaac
    10741 gggcacgagg ctgaattcct ccaagctgtt gaagaatttt tcaacacttt agaacctgta
    10801 tttgaaaaac accctgagta tatcgaagaa aatatcttgg cacgtattac tgagcctgag
    10861 cgcgtggttt ctttccgtgt tccttgggtt gaccgtgatg gaaaaattca agtaaaccgt
    10921 ggttaccgtg ttcaattcaa ctcagctgtt ggaccataca aaggtggact tcgtttccac
    10981 ccaactgtaa accaagggat cttgaaattc ctcggatttg aacaaatctt taaaaatgtc
    11041 ttgactggac ttcctatcgg tggaggtaaa ggtggatcag acttcgatcc taaaggtaaa
    11101 acagatgctg aagtgatgcg cttctgccaa agcttcatga ctgaattgca aaaacacatc
    11161 ggaccatcac ttgacgtacc tgctggtgat atcggtgttg gtggacgtga aattggttac
    11221 ctttacggtc aatacaaacg tcttaaccaa tttgatgctg gtgtcttgac tggtaaacct
    11281 cttggatttg gtggtagctt gattcgtcca gaagcaactg gttacggttt ggtttactat
    11341 actgaagaaa tgctcaaagc taacggtaac agctttgctg gtaagaaagt cgttatttca
    11401 ggttctggta acgttgctca atatgctctt caaaaagcaa ctgaactcgg tgcaactgtt
    11461 atttctgttt ctgactcaaa tggttatgtc atcgatgaaa atggtatcga cttcgatctt
    11521 ttggttgatg ttaaagaaaa acgtcgtgct cgtttgactg agtatgcagc tgaaaaagca
    11581 actgcaacct accacgaagg tactgtatgg acttacgctg gaaactatga cattgctctt
    11641 ccatgtgcca ctcaaaacga aatcaacggt gaagcagcta aacgtttggt tgctcaaggc
    11701 gttatctgtg tatctgaagg tgccaacatg ccgagcgacc ttgatgccat caaagtttac
    11761 aaagaaaatg gtatcttcta cggacctgca aaagctgcca acgctggtgg tgtagccgtt
    11821 tcagctcttg aaatgagcca aaacagtctt cgcctctcat ggactcgtga agaagttgat
    11881 ggccgtctca aagacatcat gacaaacatc ttcaacacag ctaaaacgac ttcagaaaca
    11941 tacggtcttg ataaagacta ccttgcagga gctaacattg ctgcctttga aaatgtagca
    12001 aatgccatga ttgcacaagg tattgtttaa gatttattta ctcaatcctc aatcactacg
    12061 attggggatt tttagcttga attaaaaaat tggaaaatct aattaaataa aatgaaatga
    12121 aataaaaact gaacaaattg attgcggaat tcaaaccaat ttctaacata tttctagaaa
    12181 ttaatttgac ttttctaatc gatttgttca tatcttattt caatttacta tacttacttg
    12241 acccttttta tactcaatga aaatcaaaga gcaaactagg aagcgagccg caggctgtac
    12301 ttgagtacgg taaagcaaag ctgacgtggt ttgaagagat tttcaaagag tattaaacaa
    12361 aaagaaaaac cgctactcct aagaatagcg atttaatcat gtttttaagc tactactgta
    12421 gttgctctat tatttaagtg ttatgaataa cttcaatatc tttaaagctt tttgttagat
    12481 ttataatttc aactatagcc atctctactc cttagtttac agcaaaaaat tatgcttaat
    12541 tcttattgtt tttgtaaaca atcagcgaac ccaatactat tccattcaac aagcctaaag
    12601 aaataccata ttcaactgga aaatctaaaa aaattgcaaa cactattcca atcatcaccc
    12661 ctagtgaggc tgttgttaaa attacatatt cattttcttt cttcattttc tttacacctc
    12721 atttcctttt tgtatataag ctgtagtact ctccaccaag atccattaag tacttatgat
    12781 ttcctgactc aacaatctta ccacctttca ttacaaaaat aacatccgca tccttaatcg
    12841 ttgacaatct atgagctaca attatttgag tacagccctg actttgtata tactttgtta
    12901 ttctttcctc attaatagtg tctaatgcac tagttgcttc atctaaaatt acaatactag
    12961 gattatttat taatgcacgt gccagtgcta tccgttgcct ttgcccacct gaaatatttg
    13021 accccatctc tgagatgata gtattaaatt tcatcggcat agccatgatt tcatcataga
    13081 tttgaactgc tttacaaact tcctctatct tttgtgaagt aacttcgtgc tttaaagtta
    13141 tattatcaag aatacttcgg ttcaataaaa atgaatcctg tggaactact cctaaatttt
    13201 gacttaatat ttttttatct atttgattaa tatttacacc atcaaataaa acttttcctg
    13261 tatcaatctt atataatctt gatggtattt tt
//
LOCUS       DAVEHY010000049        12555 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVEHY010000049 DAVEHY010000000
VERSION     DAVEHY010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12555
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.049"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            1..321
                     /locus_tag="VUZ44_001949"
                     /pseudo
     CDS             1..321
                     /locus_tag="VUZ44_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(528..2786)
                     /locus_tag="VUZ44_001950"
     CDS             complement(528..2786)
                     /locus_tag="VUZ44_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU0320809.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3015..3245)
                     /locus_tag="VUZ44_001951"
     CDS             complement(3015..3245)
                     /locus_tag="VUZ44_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU0320810.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3435..4118
                     /locus_tag="VUZ44_001952"
     CDS             3435..4118
                     /locus_tag="VUZ44_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU0320811.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4118..4852
                     /locus_tag="VUZ44_001953"
     CDS             4118..4852
                     /locus_tag="VUZ44_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU0320812.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5006..5863
                     /locus_tag="VUZ44_001954"
     CDS             5006..5863
                     /locus_tag="VUZ44_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU0320813.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6005..6877
                     /locus_tag="VUZ44_001955"
     CDS             6005..6877
                     /locus_tag="VUZ44_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU0320814.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     ATLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7159..7842
                     /gene="rpiA"
                     /locus_tag="VUZ44_001956"
     CDS             7159..7842
                     /gene="rpiA"
                     /locus_tag="VUZ44_001956"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU0320815.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7856..9067
                     /locus_tag="VUZ44_001957"
     CDS             7856..9067
                     /locus_tag="VUZ44_001957"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU0320816.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIYDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9069..9611
                     /locus_tag="VUZ44_001958"
     CDS             9069..9611
                     /locus_tag="VUZ44_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU0320817.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9627..10436
                     /locus_tag="VUZ44_001959"
     CDS             9627..10436
                     /locus_tag="VUZ44_001959"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU0320818.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10912..11070
                     /locus_tag="VUZ44_001960"
     CDS             10912..11070
                     /locus_tag="VUZ44_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320819.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEIT"
     gene            11089..11891
                     /locus_tag="VUZ44_001961"
                     /pseudo
     CDS             11089..11891
                     /locus_tag="VUZ44_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963254.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11916..12428
                     /locus_tag="VUZ44_001962"
     CDS             11916..12428
                     /locus_tag="VUZ44_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU0320820.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFCFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGSGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         3716 a         2296 c         2829 g         3714 t
ORIGIN      
        1 atggtgagtt aatcgctcca atgacttacg aagagacgat gacgagcgac ttttttgaag
       61 cttggtttca gaagtttctc ttaccaacat taaccacacc atcggttatt attatggata
      121 atgcaagatt ccatagaatg gggaagctag aactcttgtg tgaagagttt gggtataaac
      181 ttttacatct tccttcctac tcacctgagt acaatcctat tgagaaaaca tgggctcata
      241 tcaaaaagca cctcataaaa ggtattacca agttgcaata ccttttatga ggctcttttg
      301 tcttgttctt gtttcaattg actatagcag attgaaataa gatgagaaca aatcgattgg
      361 gaaagtaaaa ttaatttcta taaatgtttt agcaattgtt tcgtactatt tcagattcag
      421 tctactatat atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta
      481 aaaaaagaag cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt
      541 tcagaacttt taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc
      601 ataactgctt tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc
      661 tcaatatagt cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct
      721 aggtcaacca acttttcctt gaccttatca gttacatcca aacgaatgtt gttgctagag
      781 aggcgcttgt taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg
      841 agagccttaa attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta
      901 ccgagttcac cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta
      961 gcttcggtct ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta
     1021 acggtgcgtc cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc
     1081 ataacatctg ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg
     1141 cgaacttttt cagttaattg accagcctca tcatagccaa cataacctgg aggggcgccg
     1201 accaacttag ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta
     1261 tcagcagaac caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca
     1321 gttggcccaa cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga
     1381 ttacggcgaa tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac
     1441 ttgagatctt cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca
     1501 gggatattgg ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta
     1561 tcctggtctg tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag
     1621 taggccgcct tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca
     1681 atcaagcgct gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa
     1741 ccagcttcat ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga
     1801 ttggaaagag ttgcagctgc ttcaatcgca gcatctgtat attgaacgtg gtggtaatct
     1861 tcgtatttct tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg
     1921 actttaacag gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca
     1981 ttgagggtag tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata
     2041 tttcctgcgt ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca
     2101 tcgataaaga ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt
     2161 tcttcaaatt gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg
     2221 acttgtttac cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct
     2281 tcgacaacgg ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt
     2341 ctacgattga gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca
     2401 atgtctccac gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt
     2461 tcttggctag gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt
     2521 ccaccgtaac ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg
     2581 aaattgttta gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc
     2641 gtcatacctt tgaagaggct attgttagga tctgttttga taatcttata gcagttttga
     2701 cagaggtcaa tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg
     2761 ttaattttac agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg
     2821 tttaaaggtc aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag
     2881 caagtaaaaa gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac
     2941 tataaaaaaa tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc
     3001 cagcttgttt tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta
     3061 tcaaacgtat acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct
     3121 tcgtcgtggc tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt
     3181 aaatttccgc catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat
     3241 tccattttga ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt
     3301 gactagaaaa aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt
     3361 ggataaaaaa tttaaatttt aattcaaaac atgttataat catacagtat tctattttag
     3421 aaagcagtgt gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg
     3481 gggctgttgt gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg
     3541 ttgtcttggc ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt
     3601 acgtttggat tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta
     3661 tgcatatcaa tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga
     3721 ttccagggat tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg
     3781 ccggaatcaa tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc
     3841 ctaaaaatgc gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat
     3901 tggggaacga atttatcacc attatcaagg acagctccct cttatcagct attggggtca
     3961 tggagttgtg gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc
     4021 ttttatttgc agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag
     4081 cttttgaaaa acatatggga caaggagata agaaataatg acagaaacct tgataaaaat
     4141 tgaaaattta cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat
     4201 taaaagagga gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct
     4261 tcgctctatg aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga
     4321 tattacggac aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca
     4381 acaatttaac ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa
     4441 gactaaaggt gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt
     4501 tggtttgcca gataaggcag acgcttatcc acagagtctg tcgggtgggc aacaacaacg
     4561 gattgccatc gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac
     4621 ttcagccttg gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa
     4681 gtcagggatg actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga
     4741 tcgtgttatc tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt
     4801 tgaacaaacc caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt
     4861 aaaatttcaa gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac
     4921 tataggataa cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag
     4981 atatttgaaa gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc
     5041 caaattgcag gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa caggtctagt
     5101 gcctggtttg gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa
     5161 caaggagagg tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac
     5221 cattactcaa gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca
     5281 tgggattttg gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc
     5341 cattgatcca gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc
     5401 tggacatcca gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata
     5461 tgggattgac ttggaaggta aaaatgcggt cgtcatcggt cgttcaaata tcgttggaaa
     5521 acctatggct cagcttcttt tggctaaaaa tgcgacagta accttgaccc actcacgaac
     5581 tcataatctt gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc
     5641 caagtttgtg actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa
     5701 tcgagatgaa aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc
     5761 tagccatatc acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga
     5821 gcaaacttat caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa
     5881 tagagtgtat tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata
     5941 taagattaca aaaggaggtc tgcgtctcct ttttattgta taataaaagt gagaggaaaa
     6001 aaggatgaaa gtgattaatc aaaccttatt agaaaaagtt attattgaac gttctcgttc
     6061 aagtcataaa ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg
     6121 tgccatcatc atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg
     6181 aacggacagg gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc
     6241 tcttcaagac cagcaattgt taaaagagca attggagaag gcagaagttg tcttgctggg
     6301 gcctggttta cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt
     6361 aagccaaaat cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag
     6421 tttgtcattt ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt
     6481 atctggaatt acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt
     6541 ccctcaagga acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca
     6601 atctgattat taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggagc
     6661 tactctggct gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga
     6721 gcgtgtggca gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa
     6781 ttatgtggtc ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg
     6841 tcaacaagag agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc
     6901 ttctcttaat ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa
     6961 gttaagagtt tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa
     7021 ctcattttta ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa
     7081 atgtagattt gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag
     7141 aatgatggag gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag
     7201 ttcgtgagcg atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc
     7261 gaagaaatcg gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct
     7321 agtgtgacca ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta
     7381 gattttgtcg atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc
     7441 aaaggcggtg gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac
     7501 atttgggtgg tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta
     7561 gaagtggttc agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa
     7621 ccaagtttcc gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt
     7681 gacctcgcct tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc
     7741 gttggtgttg tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga
     7801 cgagatggag ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc
     7861 taaatttaat cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga
     7921 tgctaataac tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat
     7981 ttcaaaaaca gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc
     8041 tcgtgaaact cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa
     8101 attagaggaa gtatctcttg gtaaggatac tatgactgga cactgggaaa tcatgggact
     8161 caacattact gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa
     8221 aatcgaagaa ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac
     8281 ggctgttatc tatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac
     8341 ttcagctgac cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt
     8401 gtaccgtatc tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg
     8461 catcattgct cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg
     8521 tgacttggct gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat
     8581 cgatacttat gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga
     8641 catgggtcac aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact
     8701 tgctgagttt gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg
     8761 ccatcgtcgt aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc
     8821 tgaaattatc gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa
     8881 tgacccaacg tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag
     8941 ccctgccttt aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac
     9001 tgttgccgat aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt
     9061 ggtataagat gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata
     9121 aggtcgtcat ggcggagctt cgtcaagaat tgacaaactt gggactggaa aaggttgaga
     9181 gctacatcaa tagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg
     9241 aaaagctaga gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga
     9301 gtctagagga ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg
     9361 cacgaaaaga ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag
     9421 ttgaaagttt agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg
     9481 ggaaattttc tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc
     9541 ctttctaccg ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc
     9601 taaaaaaata ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta
     9661 ctttcctgaa agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac
     9721 ttggagaatt ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa
     9781 actggggccg ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag
     9841 gtcgcaaggt cttggctctt caagggcgtt tccatttcta tgaagggaat cctctggaag
     9901 tggtgacttt cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca
     9961 atgcagctgg cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca
    10021 acatgacggg gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc
    10081 cagatatgtc tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa
    10141 aacttaatat caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa
    10201 caccagcaga aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg
    10261 ttcctgaagt tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca
    10321 ctaactttgc ggccggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg
    10381 aacgtgttaa aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa
    10441 aaagatttaa aagggggagt gcctctgttt tttcaggatt gactgcctat ccggattaaa
    10501 gaagaaacag aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga
    10561 ataggtatgt ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat
    10621 tagcttccta gccaagcaga ttagtatgat aaggagagat gagaatgaat tgactttctg
    10681 aatttctcag tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata
    10741 aacgaaaaga aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa
    10801 aaaattaagt atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga
    10861 atttcagcca atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat
    10921 tctaaggagg aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga
    10981 gaggagccaa gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa
    11041 agggaagagt caaaagtaga gataacataa ccagctcaag cggatgatat ccgcaaggtt
    11101 gttggggaat tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt
    11161 ggatgttacc tagctcagat tgcagcggtt gaagcttacc aaaaatatcc tgatttttat
    11221 aaccatgtat tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact
    11281 gtttggaatg ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt
    11341 agtggaaaaa ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat
    11401 aataatcgtg atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc
    11461 tattttgaaa gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg
    11521 gataaacatg gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct
    11581 ctgcctcgat cttctagtca accaagcgct gaaccaatgg aaaatattgc ctcaggaaaa
    11641 caggttactc aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa
    11701 gtcgatggta actatggtca caattctgtc actcatacaa acttccaatc taagccttgg
    11761 tggcaagtag atttggtaaa gaagaaacca ttcgccaaat caatatttac aaccgaacag
    11821 acactgccca ggatagattg gcaaactttg atgtcattct tttagacagt tctggtaaag
    11881 aaattgagtg aaaacgtata acatctccta aagatgtgtc agcacaaatt acgattaacc
    11941 ataaaaaagc gcgctatgtt cggattgagc tagaaggcta taatgccctc agtcttgcag
    12001 aagttgaagt tttctgcttt atagctacga atgctgaaac ggcgacacaa gtttctaagc
    12061 cagttcaacc aatcagtcag actcctgtga aggataaaac attgacaatt caacacagtg
    12121 gagcttacat tgcccgctac tccataactt gggaagaagt tccagtagat aaagatggaa
    12181 accaagttgt tcgtagtcat tcttgggaag gaagcggtcg caaccagact gcaggttttg
    12241 tcctcaacct cccaatcaaa gaaaatatga gaaatctgcg agttaagatt gagaaaaaga
    12301 cgggcctact atggaataga tggcaaacaa tctatgaaaa cagaccaatt ttagctcaac
    12361 cccaccgtaa aattacccat tggggtacga cattgaattc caaggtgagt gacgatgatg
    12421 tcttgtaatc tgatggtaga atgacagtta gtttgtctag tttataagaa agtactacct
    12481 gagcttgaat aggactcagg tagctctcta tgaaagaaca aaattaatac tcaatgaaaa
    12541 tcaaagagca aacta
//
LOCUS       DAVEHY010000050        11319 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVEHY010000050 DAVEHY010000000
VERSION     DAVEHY010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11319
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.050"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            80..1426
                     /gene="cbpD"
                     /locus_tag="VUZ44_001963"
     CDS             80..1426
                     /gene="cbpD"
                     /locus_tag="VUZ44_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU0320821.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      1509..1611
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            1682..1972
                     /locus_tag="VUZ44_001964"
     CDS             1682..1972
                     /locus_tag="VUZ44_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU0320822.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            1935..2693
                     /locus_tag="VUZ44_001965"
     CDS             1935..2693
                     /locus_tag="VUZ44_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320823.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            2732..3739
                     /locus_tag="VUZ44_001966"
     CDS             2732..3739
                     /locus_tag="VUZ44_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU0320824.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            3739..4467
                     /locus_tag="VUZ44_001967"
     CDS             3739..4467
                     /locus_tag="VUZ44_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320825.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            4586..5044
                     /locus_tag="VUZ44_001968"
     CDS             4586..5044
                     /locus_tag="VUZ44_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU0320826.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            5046..7478
                     /locus_tag="VUZ44_001969"
     CDS             5046..7478
                     /locus_tag="VUZ44_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU0320827.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGNTLKI
                     GVKAGQLKFDIA"
     gene            8120..8773
                     /gene="rr06"
                     /locus_tag="VUZ44_001970"
     CDS             8120..8773
                     /gene="rr06"
                     /locus_tag="VUZ44_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU0320828.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            8770..10101
                     /gene="hk06"
                     /locus_tag="VUZ44_001971"
     CDS             8770..10101
                     /gene="hk06"
                     /locus_tag="VUZ44_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU0320829.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            10184..10711
                     /locus_tag="VUZ44_001972"
     CDS             10184..10711
                     /locus_tag="VUZ44_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU0320830.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            10790..>11319
                     /locus_tag="VUZ44_001973"
     CDS             10790..>11319
                     /locus_tag="VUZ44_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEU0320831.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEEVGGRN
                     TPTVTSSGQDISKKYADEVESHLKKILSEIQTQLDRKRHTETVALINELQGIKKTYLY
                     NLNVLKEKSKVELPSKIKAKLDVAFDQFKKDTLKPGEKVAEAQKKVAEAKKKAEDQKE
                     EDRRNYPTNTYKTLEL"
BASE COUNT         3483 a         1891 c         2621 g         3324 t
ORIGIN      
        1 ttttctcact ttttcttttt tctccgaata atttaggtga aggcaatcat cgctttatat
       61 tattttttaa ggaggaagaa tgaaaatttt accgtttata gcaagaggaa caagttatta
      121 cttgaagatg tcagttaaaa agcttgttcc ttttttagta gtaggattga tgctagcagc
      181 tggtgatagt gtctatgcct attccggagg aaatggatcg attgcgcgtg gggatgatta
      241 tcctgcttat tataaaaatg ggagccagga gattgatcag tggcgcatgt attctcgtca
      301 gtgtacttct tttgtagcct ttcgtttgag taatgtcaat ggttttgaaa ttccggcagc
      361 ttatggaaat gcgaatgaat ggggacatcg tgctcgtcgg gaaggttatc gtgtagataa
      421 tacaccgacg attggttcca ttacttggtc tactgcagga acttatggtc atgttgcctg
      481 ggtgtcaaat gtaatgggag atcagattga gattgaggaa tataactatg gttatacaga
      541 atcctataat aaacgaatta taaaagcaaa cacgatgaca ggatttattc attttaaaga
      601 tttggatggt ggcagtgttg ggaatagtca atcctcaact tcaacaggcg gaactcatta
      661 ttttaagacc aagtctgcta ttaaaactga acccctagtt agtgcaactg tgattgatta
      721 ctattatcct ggagagaagg ttcattatga tcaaattctc gaaaaagacg gctacaagtg
      781 gttgagttat actgcctata atggaagcta tcgttatgtt caattggagg ctgtgaataa
      841 aaatcctcta ggtaattctg ttctttcttc aacaggtgga actcattatt ttaagaccaa
      901 gtctgctatc aaaactgaac ccctagttag tgcaactgtg attgattact attatcctgg
      961 ggagaaggtt cattatgatc agatacttga aaaagacggc tacaagtggt tgagttatac
     1021 ggcttataac ggaagtcgtc gctatataca gctagaggga gtgacttctt cacaaaatta
     1081 tcagaatcaa tcaggaaata tctctagcta tggatccaat aatagttcaa ctgtcggttg
     1141 gaagaaaata aatggtagtt ggtatcattt caaatcaaat ggttctaaat caacaggatg
     1201 gctgaaagat ggttctagct ggtattattt gaaattatct ggtgaaatgc agacaggatg
     1261 gttaaaggag aatggctcgt ggtattatct gggtagttca ggggcaatga aaacaggctg
     1321 gtaccaggtc tctggtaagt ggtattattc ttactcttca ggcgccttag ctgttaatac
     1381 gacggtggat ggctacagag taaacagtga tggagaacga gtatagaaaa ttggagtagg
     1441 agaaatttcc tgctcttttc tgtaagcagt ttccttgaca tttttcttat tttgcgctat
     1501 catatataca tataatatat gggagtctgt gtacagtctg agaggaagtg ttaaacttcg
     1561 accgcacctg atctgggtaa tgccagcgga gggaacgata cttagtctaa ttttgcacct
     1621 tttccatgta tggtaaaggt ttttcttttt ttaaaaagga aaacgagaag aggaggttct
     1681 tatgaaagca agcattgcct tgcaagtttt acccctggca caggggattg atcggatagc
     1741 tgttattgat caggtcattg cttatctgca aactcaagaa gtgacgatgg tagtgacacc
     1801 atttgaaacg gtcttggaag gggagtttga tgagcttatg cgcattctaa aagaagcgct
     1861 ggaagtggca gggcaggagg cagacaatgt ctttgccaat gtcaaaataa atgtaggaga
     1921 gattttaagt attgatgaga aacttgagaa gtatactgag acgacacatt agtctattgg
     1981 gctttctcgg agtcttgtca atctggcagt tagcaggttt tcttaaactt ctccccaagt
     2041 ttatcctgcc gacacctctt gaaattctcc agccctttgt tcgtgacaga gaatttctct
     2101 ggcaccatag ctgggcgacc ttgagagtgg ctttactggg gctgattttg ggagttttga
     2161 ttgcctgtct tatggctgta ctcatggata gtttgacttg gctcaatgac ctgatttacc
     2221 ctatgatggt ggtcattcag accattccga ccattgccat agctcctatc ctggtcttgt
     2281 ggctaggtta tgggattttg cccaagattg tcttgattat cttaacgaca acctttccca
     2341 tcatcgtcag cattttggac ggttttaggc attgcgacaa ggatatgctg accttgttta
     2401 gtctgatgcg ggccaagcct tggcaaatcc tgtggcattt taaaattcca gtcagcctgc
     2461 cctactttta tgctggtctg agggtcagtg tctcctacgc ttttatcaca acagtggtat
     2521 ctgagtggtt gggaggcttt gaggggcttg gtgtttatat gattcagtcc aagaaattgt
     2581 ttcagtatga taccatgttc gctattatta ttctggtatc gattatcagt cttttgggta
     2641 tgaagttggt cgatattagt gaaaaatatg ttattaaatg gaaacgttcg tagaattaga
     2701 atgtttctga aaaagaaaag aggaaatcaa aatgaagaaa acatggaaag tgtttttaac
     2761 gcttgtaaca gctcttgtag ctgttgtgct tgtggcctgt ggtcaaggaa ctgcttctaa
     2821 agacaacaaa gaggcagaac ttaagaaggt tgactttatc ctagactgga caccaaatac
     2881 caaccacaca gggctttatg ttgccaagga aaaaggttat ttcaaagaag ctggagtgga
     2941 tgttgatttg aaattgccac cagaagaaag ttcttctgac ttggttatca acggaaaggc
     3001 accatttgca gtgtatttcc aagactacat ggctaagaaa ttggaaaaag gagcaggaat
     3061 cactgccgtt gcagctattg ttgaacacaa tacatcagga atcatctctc gtaaatctga
     3121 taatgtaagc agtccaaaag acttggttgg taagaaatat gggacatgga atgacccaac
     3181 tgaacttgct atgttgaaaa ccttggtaga atctcaaggt ggagactttg agaaggttga
     3241 aaaagtacca aataacgact caaactcaat cacaccgatt gccaatggcg tctttgatac
     3301 tgcttggatt tactacggtt gggatggtat ccttgctaaa tctcaaggtg tagatgctaa
     3361 cttcatgtac ttgaaagact atgtcaagga gtttgactac tattcaccag ttatcatcgc
     3421 aaacaacgac tatctgaaag ataacaaaga agaagctcgc aaagtcatcc aagccatcaa
     3481 aaaaggctac caatatgcca tggaacatcc agaagaagct gcagatattc tcatcaagaa
     3541 tgcacctgaa ctcaaggaaa aacgtgactt tgtcatcgaa tctcaaaaat acttgtcaaa
     3601 agaatacgca agcgacaagg aaaaatgggg tcaatttgac gcagctcgct ggaatgcttt
     3661 ctacaaatgg gataaagaaa atggtatcct taaagaagac ttgacagaca aaggcttcac
     3721 caacgaattt gtgaaataat gacagaaatt agactagagc acgtcagtta tgcctatggt
     3781 caggagagga ttttagagga tatcaaccta caggtgactt caggcgaagt ggtttccatc
     3841 ctaggcccaa gtggtgttgg aaagaccacc ctctttaatc taatcgctgg gattttagaa
     3901 gttcagtcag ggagaattgt ccttgatggt gaagaaaatc ccaaggggcg cgtgagttat
     3961 atgttgcaaa aggatctgct cttggagcac aagacggtgc ttggaaatat cattctgccc
     4021 ctcttgattc aaaaggtgga taaggcagaa gctatttccc gagcggataa aattcttgcg
     4081 accttccagc tgacagctgt aagagacaag tatcctcatg aacttagcgg tgggatgcgc
     4141 cagcgtgtag ccttactccg gacctacctt tttgggcaca agctctttct cttagatgag
     4201 gcctttagcg ccttggatga gatgacaaag atggaactcc acgcttggta tcttgagatt
     4261 cacaagcagt tgcagctaac aaccctgatc atcacgcata gtattgagga ggccctcaat
     4321 ctcagcgacc gcatctatat cttgaaaaat cgccctgggc agattgtttc agaaattaaa
     4381 ctagattggt ctgaagatga ggacaaggaa gtccaaaaga ttgcctacaa acgtcaaatt
     4441 ttggcggaat taggcttaga taagtagaaa aatagggagt tggtgaagat tatcctttac
     4501 cagcgccctt tttcttttaa aaatgagaaa atttcggtat aatagtcaaa caaggtcaag
     4561 gtttaaagag agaggtgggt ttgttatgag atttaaaaat acatcggatc atattgaggc
     4621 ctacatcaag gcgattttag atcaatctgg tatcgtggag ttgcaacgga gtcagttggc
     4681 agataccttt caggttgttc ctagtcagat taactacgtg atcaagacac gctttacgga
     4741 aagtagaggc tacttggttg aaagtaagcg tggtggcgga ggctacattc gtataggacg
     4801 gattgagttt tctagtcatc atgaaatgct ccgggagctg ctttactcga ttggtgagcg
     4861 agtcagtcaa gaaatttatg aggatattct ccagcttttg gttgagcagg aattgatgac
     4921 caagcaggag atgaatttgc tagaatcagt agctttggat cgcgttttag gagaagaagc
     4981 tccagttgtt cgagcaaaca tgctacgtca gatcatacaa gaggtagata gaaaagggaa
     5041 gtaagatgaa ctattcaaaa gcattgaatg aatgtatcga aagtgcctac atggttgctg
     5101 gacattttgg agctcgttat ctagagtctt ggcacttgtt gattgccatg tctaatcaca
     5161 gttatagtgt agcaggggca actttaaatg attatccgta tgagatggac cgtttagaag
     5221 aggtggcttt ggaactgact gaaacggact atagccagga tgaaaccttt acggaattgc
     5281 cgttctcccg tcgtttgcag gttctttttg acgaagcaga gtatgtagcg tcagtggtcc
     5341 atgctaaggt gctagggaca gagcacgtct tctatgcgat tttgcatgat ggcaatgcct
     5401 tggcaactcg tatcttggag agggctggtt tttcttatga agacaagaaa gatcaggtca
     5461 agattgctgc ccttcgtcga aatttagaag aacgggcagg ctggactcgt gaagacctca
     5521 aggctttacg ccaacgccat cgtacagtag ctgacaagca aaattctatg gccaatatga
     5581 tgggcatgcc gcagactcct agtggtggtc ttgaggacta tacgcatgat ttgacagagc
     5641 aagcgcgttc tggcaagtta gaaccagtca tcggtcggga caaggaaatc tcacgtatga
     5701 ttcaaatttt gagccgtaag actaagaaca accctgtctt ggttggggat gctggtgtcg
     5761 ggaaaacagc tctggccctt ggtcttgccc agcgtattgc tagtggtgac gtgcctgcgg
     5821 aaatggctaa gatgcgcgtg ttagaacttg atttgatgaa tgtcgttgca gggacacgct
     5881 tccgtggtga ctttgaagaa cgcatgaata atatcatcaa ggatattgaa gaagatggcc
     5941 aagtcatcct ctttatcgat gaactccaca ccatcatggg ttctggtagc gggattgatt
     6001 cgactctgga tgcggccaat atcttgaaac cagccttggc gcgtggaact ttgagaacgg
     6061 ttggtgccac cactcaggaa gaatatcaaa aacatatcga aaaagatgcg gctctttctc
     6121 gtcgtttcgc taaagtgacg attgaagaac caagtgtggc agatagtatg actattttac
     6181 aaggtttgaa ggcgacttat gagaaacatc accgtgtaca aatcacagat gaagcggttg
     6241 aaacagcggt taagatggct catcgttatt taaccagtcg tcacttgcca gactctgcta
     6301 tcgacctctt ggacgaagca gcagcaacag tgcaaaataa ggcaaagcat gtaaaagcag
     6361 acgattcaga tttgagtcca gctgacaagg ccctgatgga tggcaagtgg aaacaggcag
     6421 cccagctaat cgcaaaagaa gaggaagtac ctgtctacaa agacttggtg acagagtctg
     6481 atattttgac caccttgagt cgcttgtcag gaatcccagt tcaaaaactg actcaaacgg
     6541 atgctaagaa gtatttaaat cttgaagcag aactccataa acgtgtcatc ggtcaagatc
     6601 aagctgtttc aagtattagt cgtgccattc gccgtaatca gtcaggaatt cgcagtcaca
     6661 agcgtccgat cggttccttt atgttcctag gacccacagg tgtcggtaag accgagttgg
     6721 ccaaggcttt ggcagaagtt ctctttgatg acgaatcagc ccttatccgc tttgatatga
     6781 gtgagtatat ggagaaattc gcagccagcc gtctaaatgg agctcctcca ggctatgtgg
     6841 gttacgaaga aggtggggag ctgacagaga aggttcgcaa taaaccctat tccgttctcc
     6901 tctttgatga ggtagagaag gcccacccag atatctttaa tgttctcttg caggttctgg
     6961 atgacggtgt cttgacagat agcaagggac gcaaggtcga tttttcaaat accattatca
     7021 ttatgacatc gaatctaggt gcgactgccc ttcgtgatga taagactgtt ggttttgggg
     7081 ctaaggatat tcgttttgac caggaaaata tggaaaaacg catgtttgaa gaactgaaaa
     7141 aagcttatag accggaattc atcaaccgca ttgatgagaa ggtggtcttc catagcctat
     7201 ctagtgacca tatgcaggaa gtggtgaaga ttatggtcaa gcctttagtg gcaagtttgg
     7261 ctgaaaaagg cattgacttg aaattacaag cttcagctct gaaattgtta gcaaatcaag
     7321 gatatgaccc agagatggga gctcgcccac ttcgcagaac cctgcaaaca gaagtggagg
     7381 acaagttggc agaacttctt cttaagggag atttagtggc aggcaacaca cttaagattg
     7441 gtgtcaaagc aggccagtta aaatttgata ttgcataaaa gaataaaagt atcagcatct
     7501 gaccataagt cacagtggag tgaaactcaa tgaaaatcaa agagcaaact aggcagctag
     7561 ctgcaggttg ctcaaaacac tgttttgagg ttgcagatag agctgacgtg gtttgaagag
     7621 attttcgaag agtatgaaac taaaacctat agcttctaaa cgatccgtgg ttttcaccat
     7681 tcaacacaaa attcatatgt ttattaccct ccgtcgtatt tgtcttagag cgtgtgtagt
     7741 agaaaaagag cagtcttatc tgaaattttt attctttcaa aagagacctg tttctttttt
     7801 gcatgtcaaa tccgttctag ctggtatttg aaaaatcaaa ctaatattca atgaaaatca
     7861 aagagcaaac taggcagcta gccgcaggtt gctcaaaaca ctgttttgag gttgcagata
     7921 gagctgacgt ggtttgaaga gattttcgaa gagtataagc tgcaagatga atgattttct
     7981 tgtattgacg ttgttgttga caaaaagtag cggataaatg aaatccattc cattatcata
     8041 gatgataggc tggtaggaaa ttttcaaata gcatacagga aatagatgta tggagttctg
     8101 gtagtagaaa gggagagaga tgaacatttt agttgcagat gacgaggaaa tgattagaga
     8161 aggaattgca gcatttctga cagaagaggg ttatcatgtc attatggcta aggatggaca
     8221 agaggtcttg gaaaaatttc aagatctccc tatccatctc atggtactgg atttaatgat
     8281 gcctaggaag agtggttttg aagtgttaaa agaaatcaat caaaagcacg atattcctgt
     8341 catcgtcttg agtgctctgg gagatgaaac tactcagtca caggtatttg atctctatgc
     8401 tgatgatcat gtgacaaaac ctttttcttt ggtactcctt gtcaagcgta ttaaggcgct
     8461 tatcagacgt tactacgtca tagaggatct ttggcgatat caggatgtaa cagtggattt
     8521 tacctcttac aaagcacatt ataaaaatga agaaattgat ctcaaaccaa aggaattact
     8581 ggtactaaag tgtttgattc agcataaaaa tcaagtttta agtagagagc agatattgga
     8641 agaaatttca aaagatgtag ctgatttacc ttgtgatagg gtcgttgatg tctatattcg
     8701 tactcttcgc aaaaaattag ctttagattg tatcgtgact gtgaaaaatg ttgggtataa
     8761 gattagctta tgataaaaaa tcctaaatta ttaaccaagt cttttttaag aagttttgca
     8821 attctaggtg gtgttggtct agtcattcat atagctattt atttgacctt tcctttttat
     8881 tatattcaac tggaggggga aaagtttaat gagagcgcaa gagtgtttac ggagtattta
     8941 aagactaaga catctgatga aattccaagc ttactccagt cttattcaaa gtccttgacc
     9001 atatctgctc accttaaaag agatattgta gataagcgac tccctcttgt gcatgacttg
     9061 gatattaaag atggaaagct atcaaattat atcgtgatgt tagatatgtc tgttagtaca
     9121 gcagatggta aacaggtaac agtgcaattt gttcacgggg tggatgtcta caaagaagca
     9181 aagaatattt tgcttttgta tctcccatat acatttttgg ttacaattgc tttttccttt
     9241 gttttttctt atttttatac taaacgcttg ctcaatcctc ttttttacat ttcagaagtg
     9301 actagtaaaa tgcaagattt ggatgacaat attcgttttg atgaaagtag gaaagatgaa
     9361 gttggtgaag ttggaaaaca gattaatggt atgtatgagc acttgttgaa ggttattcat
     9421 gagttggaaa gtcgtaatga gcaaattgta aaattgcaaa atcaaaaggt ttcctttgtc
     9481 cgcggagcat cacatgagtt gaaaacccct ttagccagtc ttagaattat cctagagaat
     9541 atgcagcata atattggaga ttacaaagat catccaaaat atattgcaaa gagtataaat
     9601 aagattgacc agatgagcca cttattggaa gaagtactgg agtcttctaa attccaagag
     9661 tggacagagt gtcgtgagac cttgactgtt aagccagttt tagtagatat tttatcacgt
     9721 tatcaagaat tagctcattc aataggtgtt acaattgaaa atcaattgac agatgctacc
     9781 agagtcgtca tgagtcttag ggcattggat aaggttttga caaacctgat tagtaatgca
     9841 attaaatatt cagataaaaa tgggcgcgta atcatatccg agcaagatgg ctatctctct
     9901 atcaaaaata catgtgcgcc tctaagtgac caagaactag aacatttatt tgatatattc
     9961 tatcattctc aaatcgtgac agataaggat gaaagttctg gtttgggtct ttacattgtg
    10021 aataatattt tagaaagcta tcaaatggat tatagttttc tcccttatga acacggtatg
    10081 gaatttaaga ttagcttgta gacagattag ttttttatta aagttcatat agggttaaca
    10141 taagtgtgtt attctttgta tagataaaag aaaggatact aatatggtat tagcgattat
    10201 tttagtaaca ttctttattc gattgatttt tttaaagcgt tcgatagaga atgagaaacg
    10261 aatccttagc aatggcggga aagaatttgg agttgagaat acaaaacgat taacgttggc
    10321 tcatattgtt ttttatctct cttgcctcgt tgaagcaatg gtgcataaga caatgtttga
    10381 tggtatgagc atggttggtt tagtcttgct tattttttct atgctgatgt tgatgttggt
    10441 gattcacttg ttgggagata tttggacagt gaagcttatg cttgtcaata atcacaaata
    10501 tgtagatcat atcttgttta ggacagtaaa acatcctaat tactttttaa atattttacc
    10561 tgagttgatt ggcttgacct tgttgagtca tgcttatgtg acttttgttt tagtttttcc
    10621 agtttatgca gttattttgt atcgacgaat agctgaagag gaaaagctat tacatgaagt
    10681 tataatccca aatggaagca taaagagata aatacaaaat tcgatttata tacagttcat
    10741 attgaagtga tatagtaagg ttaaagaaaa aatatagaag gaaataatta tgtttgcatc
    10801 aaaaagcgaa agaaaagtac attattcaat tcgtaaattt agtattggag tagctagtgt
    10861 agtagttgct agcttgttct taggaggagt agttcatgca gaagaggttg gtggtaggaa
    10921 tacccccacg gttacatcta gtgggcaaga tatatcgaag aagtatgctg atgaagtcga
    10981 gtcgcatcta aaaaaaatat tgagtgagat ccaaacacaa ttagatagaa aacgacatac
    11041 cgaaactgta gcgctaatta acgagttgca aggcattaag aaaacgtatt tgtataattt
    11101 aaatgtttta aaagagaagt cgaaagttga gttgccgtca aaaataaaag caaagttaga
    11161 cgtagctttt gatcagttta aaaaagatac attgaaacca ggagaaaagg tagcagaagc
    11221 tcagaagaaa gttgcagaag ctaagaaaaa agccgaggat caaaaagaag aagatcgccg
    11281 taactaccca accaatactt acaaaacgct tgaacttga
//
LOCUS       DAVEHY010000051        10889 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVEHY010000051 DAVEHY010000000
VERSION     DAVEHY010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.051"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(8..1222)
                     /locus_tag="VUZ44_001974"
     CDS             complement(8..1222)
                     /locus_tag="VUZ44_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU0320832.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1378..1671)
                     /locus_tag="VUZ44_001975"
     CDS             complement(1378..1671)
                     /locus_tag="VUZ44_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320833.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1833..2285
                     /locus_tag="VUZ44_001976"
     CDS             1833..2285
                     /locus_tag="VUZ44_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU0320834.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2320..3708)
                     /locus_tag="VUZ44_001977"
     CDS             complement(2320..3708)
                     /locus_tag="VUZ44_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU0320835.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3774..4736
                     /locus_tag="VUZ44_001978"
     CDS             3774..4736
                     /locus_tag="VUZ44_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU0320836.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQTLKDYIEG"
     gene            complement(4765..5103)
                     /locus_tag="VUZ44_001979"
     CDS             complement(4765..5103)
                     /locus_tag="VUZ44_001979"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320837.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVG
                     SKHVFEVVDETNEVSSKHCFEVADETDEVSSKHCFEVADETDEVSSKHVFEVVDETDE
                     VSNHTYGKAT"
     gene            complement(5167..6177)
                     /gene="ccpA"
                     /locus_tag="VUZ44_001980"
     CDS             complement(5167..6177)
                     /gene="ccpA"
                     /locus_tag="VUZ44_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU0320838.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6602..7201)
                     /locus_tag="VUZ44_001981"
     CDS             complement(6602..7201)
                     /locus_tag="VUZ44_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU0320839.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEMVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7203..8300)
                     /locus_tag="VUZ44_001982"
     CDS             complement(7203..8300)
                     /locus_tag="VUZ44_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU0320840.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(8300..9037)
                     /locus_tag="VUZ44_001983"
     CDS             complement(8300..9037)
                     /locus_tag="VUZ44_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320841.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(9039..9923)
                     /locus_tag="VUZ44_001984"
     CDS             complement(9039..9923)
                     /locus_tag="VUZ44_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320842.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(9910..10104)
                     /locus_tag="VUZ44_001985"
     CDS             complement(9910..10104)
                     /locus_tag="VUZ44_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320843.1"
                     /translation="MKKGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(10101..10307)
                     /locus_tag="VUZ44_001986"
     CDS             complement(10101..10307)
                     /locus_tag="VUZ44_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320844.1"
                     /translation="MEEEEMKNKMIVAVSLVTAGVMTYLMFSGLDEGFYHFPWELFAG
                     FGMMSWLIREGLKLVSDVKKEFEE"
BASE COUNT         3323 a         2470 c         1950 g         3146 t
ORIGIN      
        1 gcaagcccta tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta
       61 actcatcaac acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc
      121 ctcgaccatg aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat
      181 catcatcgat acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg
      241 gtttaacggc agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct
      301 cgtagattcg tccaccagga agaagcaatt catcgactga ttggtgcccc cccaaggaag
      361 tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga
      421 gcccttcgat atagccctta acatgagtct tagggccaga caagaccatc caacccacac
      481 gaaaacctgc tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg
      541 gtgccaagct cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt
      601 catccgcaaa gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt
      661 ccttaggata aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat
      721 tggaagtgat ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac
      781 agatatagtg aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt
      841 ctggcattgg cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa
      901 tcaactcact gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct
      961 tcagctggca atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat
     1021 agccttcact atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa
     1081 agccaaattc tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca
     1141 tccgcatggc ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac
     1201 tagacttgtt atattctttc atcttgtttc ctcaattcat caggatagta acattatacc
     1261 actagaaaga gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa
     1321 accttgctaa aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca
     1381 cataccaaaa gataagccta gaaaaagcaa gcctagaaag gagtcataaa gaagattaaa
     1441 catgaggaaa agcccccata tcatcaagta atcccaacgc ccacttcgtt ttgcaactag
     1501 aaataagatt agatggtaga gtacatgaaa gactaaaaat ccaataaaac ttggataaag
     1561 aagcggtacc agactctcta attgacagat catgatcact tttaccaaga ctgaaactag
     1621 gataattcca taatacagga aatttgattt ttgaaaagag tttttcatca ttctcccttc
     1681 cttcacttct ttccttctat cctttctttt attttatcat atatttatat agattttaag
     1741 ccctaatatt cttttgaaaa atactttttt tactttactt ctatagtgaa aaggtttaca
     1801 attatagtaa gaaaatttca ggaggtttca ttatggcaca acgttaccaa aatatcatgg
     1861 tcgcaatcga tggttctaag gaagcggact tggcttttgt caagggagtt cattctgctc
     1921 tacgaaacga cgctaaactc accatcgcac atgtcattga cacacgcgct ctccaaagcg
     1981 tatccacctt tgatgctgaa gtttacgaag aactccaagt cgacgctgaa agtctgatga
     2041 aagagtacga aaaacgtgct aaagatgctg gggtagcaga tgttcatatc gtcattgaaa
     2101 tgggaaatcc aaagaccctg ctagcacgta ctattccaga tgccgaggaa gtggacctca
     2161 tcctcgttgg cgcaactggt ctcaacgcct ttgaacgcct cttggtcggc tcttcatctg
     2221 aatacatact ccgccatgct aaggtcgatt tgctggttgt gagagaacaa gaaaaaacct
     2281 tataatcaca aagaaaagga gcccctagct cctttttgtt tacgatttat ttctctcttt
     2341 atggcgttcg taagccttga gctggcgctg cagttccttt ttaatagcag gttctggagc
     2401 atatttttct tcccaattat ctggttttaa gattttatgg gtcactggat caaaatgagc
     2461 cttgccatct ggaaaaattt tccccatatt ggcctgatgg acaatatcaa aaatacgttc
     2521 tgggtccacc cccatcaaga caaaactgcc gtaggtgaag taaagcgtgt caatcaaggc
     2581 atccacttgc cctatcaaat cttgctgagc aggtgtcttc ttggctactt tacctgctgc
     2641 cttatcaagg gcctgatgaa gttgcgatac agcttgacca aaatcttctt cagaaggact
     2701 ggctgctcga acaaactcca ccaattcttc tattttaaaa ccagccctat gggttgcacc
     2761 ctctaaatcc caagctcgag gttcttcttg ggttcgttca tccatcatgt ggtggaaggt
     2821 cttgacctta ttgaaatgat agtcacggct gacaaagact ttttctgaag acaaaacacc
     2881 aaaatgttcc aaggccttgt ggatcccatc ttgttgattg ctagtggtaa tgtgcttggc
     2941 agcttccttg acactgctac taccatttcc catagcgacc gacataccga cgccagccag
     3001 catttcaagg tcattatctg agtcaccaaa agccatgact tgattgaggt caaagccata
     3061 ttctttccca actcggcgaa tgccttctaa tttagaattt ccctgattga tgacatccga
     3121 tgcaaaagga ttgctacgtg tcaatttcaa gtcttcaaaa tcagctgccg ccttctcaga
     3181 ttcttctggt gtcatcagca tcaaaacttg gtagataggc tgattcatca ggtgaagcag
     3241 gtcctcttcc ttttggggaa caaccttgct gaccatgcga ttaaaagact gactcaccgt
     3301 ccgagttaaa acagagggaa cgaagcgact aattcgttgg gaaaaagaac ccagaccaaa
     3361 ggacatgatt ttagaaccca acatggcatc cttggtccct agagcaatct ccgtgccctc
     3421 ttttttagca tagctaatta gatggcgcaa atgtaacttg gaaatagggc tcgtgaacaa
     3481 gactctgtct ttactaaaga tatactggcc attataggtt accgcaaaat ccagatccaa
     3541 atcgtccatc aattccttaa caaaaaaagg tcctcgccct gtcgctacgc caactagtac
     3601 cccttgttct ttgacaatct taatcgcatc cttagtggat ttcaaaacac tcttgcgatt
     3661 gttgaccaag gttccatcga tatcaaaaaa aacagctttg acttccatcc tatcccaatc
     3721 tccccttttg tgatacaatg attataccac atttcagaaa gagtgagtaa atcatgccta
     3781 agaaaatcct tgttttacat acgggtggaa ctatttccat gcaggccgat gcttctggcg
     3841 ctgttgtgac gagttcagat aatcccatga accatgtgtc caacccactt gaaggaatcc
     3901 aagtccacgc cttggacttt tttaaccttc caagtcccca tatcaaaccc aaacatatgc
     3961 tggtcctcta ccagaaaatt aaagaggaag cagataacta cgatggagtg gtgatcacac
     4021 acggaaccga tactttagag gaaacagcct atttccttga taccatggaa gttccccata
     4081 tgcctatcgt tctaacagga gccatgcgta gctccaatga gctcggtagt gatggtgttt
     4141 ataattatct aagtgcttta cgagtggcca gcgatgacag ggctgctgac aaaggagttt
     4201 tggtcgttat gaacgatgaa atccacgctg ccaagtatgt caccaaaaca catacgacta
     4261 atgtcagcac cttccagact ccaacacatg gccccctcgg tctcatcatg aaacaggaaa
     4321 tcctctactt caaaacagct gaacctcgtg ttcgctttga ccttgatcac atacaaggtt
     4381 tagtccctat catctcggct tatgctggta tgacagatga gctgattgat atgctggatt
     4441 tagaacactt ggacggtttg attatccaag ccttcggagc tggtaatatt cccaaagaaa
     4501 cggctcaaaa attagaaagc cttctgcaaa aaggaatccc agtcgctctg gtatcacgat
     4561 gctttaacgg tattgccgag cctgtttatg cctaccaggg tgggggcgta cagttgcaaa
     4621 aagcaggcgt tttctttgtt aaagaactca atgcccaaaa agctcgcttg aaactcctca
     4681 tcgccctcaa tgccggacta acaggacaga ctttgaaaga ctatatagaa ggctaatact
     4741 cttcgaaaat ctctgcaaac cacgtcacgt cgccttaccg tatgtatggt tactgacttc
     4801 gtcagtttca tccacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctgc
     4861 aacctcaaag cagtgctttg agctgacttc gtcagtttca tctgcaacct caaagcagtg
     4921 ctttgagctg acttcgttag tttcatctac aacctcaaaa acatgttttg agccgacttc
     4981 gtcagttcta tctgcaacct caaagcagtg ctttgagctg acttcgtcag ttctatctac
     5041 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     5101 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     5161 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5221 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5281 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5341 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5401 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5461 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5521 taccaaaccc tcactataag tgattcctgc ttttttcaag gtttccttgt agccaactaa
     5581 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5641 ttctttagca aggtaactca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5701 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5761 aaattctgag cgaattttat ctgtcaagtg ataccccata tagataatgc catctacctg
     5821 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5881 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5941 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     6001 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     6061 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     6121 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6181 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6241 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6301 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6361 agaaaaccta ggtttagctc cttgctacca ccttagacta aacaaaaagg aggaaactaa
     6421 gccctcctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6481 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6541 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6601 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6661 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6721 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6781 ctgtcaacgg attgggacgg gtcatcacca tttccatcaa ttcaggcgaa tactccttgc
     6841 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6901 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6961 tcaccacaac cacctttgtt tcaagctttt ctgatcgtat ccactccaag acttcaagac
     7021 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     7081 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     7141 tgagcaattg acacatggca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7201 tcttagtttc tctccttata aggtagtcga acttgcactt ccgttggatg tttctgactg
     7261 attacactta cttctcctga aaatggaaaa acacgatctc ggactgtatg gagctcatct
     7321 ccttttagaa aagcaaagcc gcagccatca tcacttactg ttaaaatgag ttccttctct
     7381 gtccgttcta attttaagta agctttagac gctttggcat gtttgatgat attggtcacc
     7441 aactcaagca aaatcataga agccattgac tccaattctt gagtaaggct agcagtatct
     7501 agttggttat ccgtttccac ctcaattcca gcaatttcta acatcttttt cacagtctct
     7561 agttcggatg tcaaagttct agacttaaga ttttccacga tagttcgaac ttcattcatg
     7621 gaatccttgc tgatctggtg aatttctttt aattcctttt ccacctgtgg ataagcctcc
     7681 atctgaaata actgcaaggc tagatcagtt ttaacactaa gcatagcaaa ggtatgcccc
     7741 agactatcat gcaaatcttg accgatacga ttgcgttcat tttcagcaag caatagattt
     7801 atctgggcat tttgcttagc ctgtgcttct ttcaaatcct ccacaattcg aatccgaacc
     7861 aagccaaaag tcattaaatc gacaaaagca agaattacaa gtagatagaa tagaaactca
     7921 acttcgattc tctgaaaaat caacagttgc cccacaacaa ggacttgagc aagaagaaaa
     7981 gtccagacat gtaaagactt taaactacgt acgctgaaat gataacttaa gagattggat
     8041 aggaaaaaga aaaaccagat ataattaaca gcaacaaagg cagtattccc aactacataa
     8101 gtcagcagga tgccccaata tagccaagat aggcgctggc tcttagttgt taaaacaccc
     8161 aaatatgcca ctacaaatag aatatcaacc aataaatgcc aagcaggaag ctccccaatc
     8221 actacaggta ggatgggaaa aagcataaaa atcaaactgg tccaaaacat atagtgtatg
     8281 cttttcagtc tttcaagcat taagcattct ccttatgacc ttgaaggtaa atagtcaaac
     8341 caaataaaac tgctgaaaaa acaagtaaat aaactgtggc tgatagattg atgtcaccct
     8401 cgtttaagaa ggtcttgagc aactccatca attgataggt cgggagacac ttaccaactg
     8461 cttgcatcca gtctggaaat aaagaaatgg gcatccagag tccgcctaaa acagccaatc
     8521 ctagataaag aagattgccc acaacagaca tcagctgact agttggtaag agagtcaagg
     8581 tcaagccaag tgctacaaaa gcaatactcc ccacaatcag caaaatcgca gctccaaccc
     8641 attttactag aggcatgtct acacctctta caaaatgtcc aactgtaaaa acaaccagaa
     8701 ttgagaccaa ataatcaacc agcatacttg ttatctttga tagataatat tctaccatat
     8761 ttacagggct atgacgcaat gttttctgcc agttgttcat cttatcggta tgtaaaacag
     8821 ctggaaatga gaggatagtt gtcgacatca tggaaaaggc agtcatggag atgaggtaat
     8881 cacgcataaa attcgcgagt tcacctggtg tgtcctgata gataccagaa aaaaataaat
     8941 agaaagccgt cggcatccct accgacaata gataatagat taattgtcgt ttggtcaata
     9001 aaaattctat cttactaagt gctatccatc gtttcatctt agttatctcc cttctgcgtc
     9061 tcttcaaaga ttgtattcaa caaactacga ttattaactt cgatttcttg catcctacat
     9121 cctgcttggg ctaatagttc ccagaaagca tctgcttctc gagtgactac ttgtaaagaa
     9181 tcttgcttta gggtccagtt ttcaaccaaa tttgactgct ctacgacttc cttgtaagct
     9241 ataggaagga taaagtgctt ttctatttcc tcgctacgca tagctagagg cgtcgtatct
     9301 cgaatcaact ctcccttatt taagagcaaa atgcggtctg cagtgtgttc cacttcctca
     9361 atataatggg acgaatagag aatggtgact ccttgcgctt ttaactcctg gacaatttcc
     9421 caaaaacgtt gacgagttga ggtatccatg gacgcagtag gctcatctaa aaaaacaatc
     9481 tttggtcgcc caattaaggt caagacgaaa gaaaagagac gcttttgacc gcctgataat
     9541 ttttctgcca actgttcttt ttgttgcttg acaaactgca atagttgatc aatttcctga
     9601 ttgctcaaag gatttggata gatacgttga aagaaagcaa tcaactcttt aacttttaat
     9661 ttctgaacga ttacattttc ttgagggagg taagccctag tatagtctaa cttagaactc
     9721 gtcactggta aaccttgaat agatacttga ccgcttgtga ccagtttatc tccaagcaaa
     9781 caatctaaga gtgttgtctt tccggcacca tttggaccaa ttaaggcaac acattcacca
     9841 tcgttgattt caaaggagat attccgcaaa atttccttgt cttttatttt cttactcaat
     9901 ttctcaactt taaccaccgt catgagactc tcctttcaac cactccattc ccataaggaa
     9961 aacgacgaaa atcataaatc caaaccccaa agcaccacga atgaattggc gaagcaaggc
    10021 ttgatcaaac caatcagtaa acatttccac taaccatacc aagagtgaca ggccgataaa
    10081 gaaatagatg atccctttct tcattcctca aactcctttt tcacatctga gactaatttc
    10141 aaaccttctc ggataagcca ggacatcatt ccaaatcctg caaatagctc ccaaggaaaa
    10201 tgataaaatc cttcatccaa tcctgaaaac atgagataag tcatgactcc tgcggttact
    10261 agactcactg cgacaatcat tttatttttc atctcttctt cctccatttc atacttcaat
    10321 tatagacttt tgaagtttgc ggagctagat gcttctgtca ctaggaaata tgacaaatgt
    10381 cataaaagat tctgttcaaa acaagcaaga tacactatac aataaaacac aatcagaaaa
    10441 atctaaggca acttcctcaa aagagatatc aaacccaatt cacaccataa tgtaaactaa
    10501 tacttattta aaatcaaaaa gagtagaaat ttttatcaga caaacacata tatagtgtat
    10561 tgaatctata acagtaggcc ttaaatacta aaatatttct ataaattaat ttaactttcc
    10621 tgatagagct gttcatatct tatttcaatt ctctatatta tacgttgaac aaaacccttc
    10681 tattgctttc ttaaaaattt ataagagtta taaaatctgt taaatttcaa tgtgtatacc
    10741 taaactacgg tatttattga aaagactgga gacaaaaagt atacgctgcc aaaatgaatt
    10801 actgaaaatc aaaaaagaga gaaccaaact gattccctct taatgtatat aatatctagt
    10861 tttaaaaata cacactcaca tatctctgt
//
LOCUS       DAVEHY010000052        10868 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVEHY010000052 DAVEHY010000000
VERSION     DAVEHY010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.052"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..232)
                     /locus_tag="VUZ44_001987"
     CDS             complement(<1..232)
                     /locus_tag="VUZ44_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0320845.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKVTKPRKVDRDRLKNYLTDNPDAYL"
     gene            403..558
                     /locus_tag="VUZ44_001988"
                     /pseudo
     CDS             403..558
                     /locus_tag="VUZ44_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            758..4033
                     /gene="rexB"
                     /locus_tag="VUZ44_001989"
     CDS             758..4033
                     /gene="rexB"
                     /locus_tag="VUZ44_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU0320846.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEVMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILTP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQTEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNHYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            4030..7680
                     /gene="addA"
                     /locus_tag="VUZ44_001990"
     CDS             4030..7680
                     /gene="addA"
                     /locus_tag="VUZ44_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU0320847.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILNQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SKSFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLAHVVAISKEKNGRALTNASRKADLKPLADAYNEERKTR
                     FAKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7895..9073
                     /locus_tag="VUZ44_001991"
     CDS             7895..9073
                     /locus_tag="VUZ44_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320848.1"
                     /translation="MTLPVRKSLHDAVLQASKANTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9282..>10868
                     /gene="iga"
                     /locus_tag="VUZ44_001992"
     CDS             9282..>10868
                     /gene="iga"
                     /locus_tag="VUZ44_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HEU0320849.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYHEETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPKYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQG"
BASE COUNT         3486 a         2180 c         2259 g         2943 t
ORIGIN      
        1 tcaaataagc gtctggattg tcagtaagat agtttttaag tctatctcta tcaacctttc
       61 ttggttttgt tacttttact tggtggttta gctctcctgt tttctctttt agctttaacc
      121 agccataaat ggtattacgt gagatttgga aaacgtgtga tgcttctgtt atactacctg
      181 ttcgctcaca ataagagaga acttttttac gaaaatctat tgaatatgcc ataagaagat
      241 tataccacat tgtgtactat ttttggttca ttttactata ttagattgaa ataagatacg
      301 aacagcttga ttagggaaat caaattaatt tctagaaata ttttagcatc cacgatgtac
      361 tattatagtt tcaatttact atagttcaat cattctatca agaatattga atatataaag
      421 gcacgtaata ttaaaacttc ttctgatatc gaattagagt ccgatgttga tggcgataaa
      481 tcagacaatc tacccgtcga cattaagata ctgggacaac acattgaagt gtattccgta
      541 cctaagaaac aatcataaaa ctcaaagtct tgctaccgag gcttttttat tatgtgattt
      601 tcagtagcca gacttattct atctaataca agtaaagcta agtatttaag atttagcaga
      661 tgatgaagaa aagaaaggat ggcctaaata ttttaacaga tttacgaggc taatcatggt
      721 ataatatagg gtgatgaaaa attccaacga ggctgagatg aaattacttt atactgatat
      781 tcgaacttct ttgacagaaa ttctaacaag agaggcagaa gagctagttg cagctggcaa
      841 gcgggtcttc tacattgccc ccaactctct ttcttttgaa aaggaacgcg ccgtgctgga
      901 atgcttgtcc cagcaggctt ctttttcgat taccgtcacg cgctttgctc aaatggctcg
      961 ttatctggtc ttgaatgatt taccagttaa aactactctt gatgatatcg gtcttgggtt
     1021 ggccttttac aaatgccttg ccgaactcga tcccaaggac ttgcgtgttt atggcgctat
     1081 taagcaggat cctcaattga tccagcagtt aattgagctt taccatgaga tgaccaaatc
     1141 tcagatgagt tttttggact tggagaattt aacagatgag gataagaggg cggatttact
     1201 cttgattttt gagaaagtaa cagcctatct taatcaaggt cagttagccc agggaagtca
     1261 gttgtcccat ttgattgagg ctattgagaa tgacaaggta agtagtgatt ttaatcaaat
     1321 caccttggtc attgacggct ttactcgttt ttctgctgag gaagagcggg ttgtggactt
     1381 acttcacggc aaaggtgttg agattgttat cggggcttat gctagtaaga aagcctatac
     1441 cagtcctttt agcgagggca atctctacca agccagcgta aaatttctcc atcatctggc
     1501 ttctaaatac caaacgcctg ctcaggactg ttctcaaact catgagaaga tggatagttt
     1561 tgacaaggcc tctcgtttgt tggagtcttc ttatgacttt tcagaactcg ctttggatgt
     1621 cgatgagaaa gaccgtgaaa atttacaaat ctggtcttgt ttgacgcaaa aggaggagtt
     1681 ggagctagta gcccgtagca ttcgtcagaa attacatgag aactcagacc tgagctacaa
     1741 gcattttcgt attctcttgg gggatgtagc ttcttaccag ttatctctca aaaccatttt
     1801 tgaccagtat cagattcctt tttatcttgg tagaagcgaa gtcatggctc atcatccctt
     1861 gactcagttt gtcgagtcta ttttagcttt aaaacgttac cgttttcgtc aggaggattt
     1921 gattaatctt cttagaactg atttgtatac tgacctcagt cagtctgata ttgatgcttt
     1981 tgagcaatat atccgctatc ttggtatcaa tggcttgcca gcctttcagc aaaccttcac
     2041 caaatcccac catggaaaat ttaatcttga gcgtttgaat gtcctccgcc tgagaatttt
     2101 aacacctctt gaaaccctct ttgccagccg aaaacaaaag gctgaaaacc tcctacaaaa
     2161 atggagtgtc tttctaaaag aaggagctgt gactaagcag ttacaagatt tgacaaccac
     2221 tttggaagct gtagaacagg aaagacaaac cgaagtttgg aaggctttct gccatgtttt
     2281 agaacaattt gcgactgttt ttgctggttc acaggttagt ctggaagact tcctagcctt
     2341 gctccattct ggaatgagtt tgtcccaata ccgtaccatt ccagcaacag tggacactgt
     2401 tctggtgcag agttacgatt tgattgcacc attgactgct gactttgtct atgctattgg
     2461 actaactcag gacaatttac caaaaatttc tcaaaacacc agtcttctga cagatgaaga
     2521 aaggcaaaac ctaaaccaaa cgaccgaaga aggcgttcaa ttactgattg ccagcagtga
     2581 aaatctcaag aaaaatcact acactatgct ttccttggtc aattctgctc gtaagcagtt
     2641 gttcttgtcg gctccaagcc tttttaacga aagtgaaagt aaggaatctg cctatcttca
     2701 agagttgatc cattttggat ttaggcggag agagaagagg atgaatcaca aaggactgtc
     2761 taaggaggat atggggtcct atcacagtct tttgtctagt ctggttgcct atcaccagca
     2821 gggtgagatg agcgatactg agcaagattt gacttttgtc aaggttctgt cgcgtgtcat
     2881 aggtaaaaaa ctagatcagc aaggtctgga aaatccagct atcccaacca gtccaagcag
     2941 caagacctta gccaaggaca ccttgcaagc tctctatcct gccaaacagg agttttacct
     3001 gtctacgtcg ggtttgacag agttttatcg caatgaatac agttatttcc tacgctacgt
     3061 tttaggcttg caggaggaat tacgtttgca tcctgatgcc cgtagtcacg ggaatttctt
     3121 gcatcgtatc tttgaacgcg ccttacagtt gcctaatgaa gattcctttg accaacgtct
     3181 agaacaagct attcaagaaa ccagtcaaga acgcgaattt gaagctattt atcaagaaag
     3241 tttggaagcc cagtttacca aggaagtttt gcttgatgtt gcacggacga ctggacatat
     3301 tctccgacac aatccagcca tcgaaaccat caaagaagaa gcaaattttg gtggaaaaga
     3361 ccaagccttt attcaattag acaatggacg cagtgtcttt gtacgaggca aggtggaccg
     3421 gattgaccgt ttgaaagcta atggagcgat aggagtagta gactacaaat ccagtctgac
     3481 tcagttccag tttcctcatt tctttaatgg gctcaattct cagttaccaa cctatcttgc
     3541 tgccctaaaa agagaagggg agcagaactt tttcggcgcc atgtacttgg aaatggctga
     3601 acctgtccaa tctctgatgg cggtaaaaag tctggcagga gcagtggtag aagccagcaa
     3661 atctatgaaa taccaagggc tcttcttgga aaaagaaagc agttatttag gcgaatttta
     3721 taacaaaaac aaggctaatc aactgacaga tgaggaattt cagctcctac tggactacaa
     3781 tgcctatctt tacaagaaag ctgctgagaa gattttagca ggccggttcg ccatcaatcc
     3841 ttatactgaa aatggcagaa gcattgcccc atacgtccag caacatcagg ctattacagg
     3901 ctttgaagcc aattaccatc tgggccaagc ccgtttccta aaaaagttgg acctagctga
     3961 tggcaagcgt ctggtcggag aaaaactcaa gcaagcttgg tttgaaaaaa taagagagga
     4021 gttaaatcga tgaagcttat tcccttttta agtgaggagg agattcaaaa actgcaagaa
     4081 gcagaagcaa attcgagcaa ggaacaaaag aaaactgccg agcaaatcga agctatctac
     4141 acttctggcc agaatatcct ggtctcagca tcggctggtt ctggaaagac ctttgtcatg
     4201 gcagagcgca ttctgaacca attggcgcgt ggtgtcgaaa tttctcaact ctttatctca
     4261 acctttaccg tcaaggctgc aactgaactt aaagaacgtt tagagaaaaa aatcagcaag
     4321 aaaatccaag aaacagatga tgtcgagctc aaacaacact tgggtcgcca gttggcagac
     4381 ctacccaacg ctgccatcgg aaccatggac tctttcacac aaaaattcct tggcaaacat
     4441 ggttatctgc ttgatattgc acctaatttc cgtattttac aaaaccaaag cgagcaactt
     4501 cttctcgaaa acgaagtctt tcatgaggtc tttgaagcgc attaccaagg taaacagaaa
     4561 gagaccttta gtcatttgct gaaaaacttt gctggacgtg gcaaggacga acggggtctg
     4621 cgccagcagg tctataaaat ctatgacttc ctccaatcca ccagtaatcc tcaaaagtgg
     4681 ctgagtaaat ctttcctcaa aggttttgag aaagctgatt ttaccagtga aaaagaaaaa
     4741 ctgactgagc aaatcaaaca agccctttgg gatttggaaa gctttttccg ttaccatctg
     4801 gataacgatg ccaaggagtt tgcaaaggct gcctatttag aaaatgttca gttaattctg
     4861 gatgaaattg gctccctaaa tcaggagtcc gatagtcagg cttatcaggc agtgcttgcg
     4921 catgttgtcg ccatctctaa ggagaaaaac ggtcgagctc tgactaatgc cagccgtaag
     4981 gctgatttga agcccctggc tgatgcctac aacgaagaga gaaagacccg gtttgctaaa
     5041 ctaggacaat tatcagacca gataaccatt ctcgactatc aagaacgtta tcatggagac
     5101 acttggaaac tagctaaaac cttccaatct ttcatgagcg attttgtgga ggcttatcgt
     5161 cagagaaaac gacaggaaaa tgcctttgaa ttcgctgata tcagccatta caccattgag
     5221 attttagaga atttcccaca agttcgtgag tcttatcagg agcgcttcca tgaagtcatg
     5281 gtcgatgagt atcaggatac caaccatatt caagaacgga tgctggaatt gttgtctaat
     5341 ggccacaatc gctttatggt gggagatatc aagcaatcca tctatcgttt ccgtcaggca
     5401 gacccgcaga ttttcaatga gaaattccaa cgctatgcgc aaaatcccca agaaggcaag
     5461 ctcattctcc tcaaggaaaa tttccgtagt agttcagaag tgctgtcagc aaccaatgat
     5521 gtctttgaac gtctcatgga ccaagaggtc ggcgaaatca actatgataa catgcaccag
     5581 cttgtttttg ccaataccaa actgactccc aatccagaca acaaggccga atttctcctc
     5641 tacgacaagg acgatacagg tgaggaagaa gagagtcaaa cagaaacgaa actaacaggt
     5701 gaaatgcgct tagttatcaa ggagatcctt aaacttcatc aggaaaaagg tgttgccttt
     5761 aaggaaattg cccttctgac ctctagtcgt aatcgtaatg accaaattct acttgccctg
     5821 tctgagtacg ggattcctgt caaaactgac ggagagcaaa acaattatct ccaatcccta
     5881 gaagtgcaag tcatgctaga cactcttcgt gtcattcaca atcccctgca agactacgcc
     5941 ttggttgccc ttatgaagtc tccaatgttt ggttttgatg aggatgagct agcacgtttg
     6001 tcccttcaga aagcagagga taaagcccac gaaaatctct atgagaaact ggtcaatgca
     6061 caaaaaaagg caagtagtca aaaaggcttg attcacacag ctctagctga aaaactaaag
     6121 caattcatgg atatcctagc ttcttggcgc ttgtatgcca aaccccactc tctctatgac
     6181 ttgatttgga agatttacaa cgaccgtttt tattatgact atgttggggc tttgccgaat
     6241 ggtcctgcta ggcaggccaa tctctatgcc ctagcactgc gtgctgatca atttgaaaag
     6301 agcaatttca aaggtttgtc gcgttttatt cgtatgattg accaagtctt agaagcccag
     6361 cacgatttgg caagcgtggc cgtcgcaccg ccaaaagatg cagtagagct catgaccatc
     6421 cacaagagta aagggctgga gtttccttac gtctttatcc tcaatatgga tcaagatttc
     6481 aacaagcaag actctatgtc agaagtcatt ctcagtcgtc agaatggtct tggtgtcaaa
     6541 tatattgcca agatggagac aggggcagta gaagaccact atcctaaaac catcaaactc
     6601 tccattccta gtctgaccta taggcagaac gaagaggaat tacagctagc aagctattct
     6661 gagcagatgc gtttgctgta tgttgctatg acgcgggctg agaaaaagct ctatcttgtc
     6721 ggcaagggtt ctcgtgaaaa gctggaagcc aagcaatacc cagcagccaa aaatgggaaa
     6781 ctaaatagca atactagact gcaagcacgg aatttccaag attggctttg ggctatcagt
     6841 aaagtgttta ctaaggacaa gctcaacttt agttatcgtt ttattgacga agatcagttg
     6901 accagagaag ctatcggaga gttggaaacc aagagtcctc tccaagatag ctcccaagca
     6961 gacaatcgtc agtcagatac catcaaagaa gctctggaaa tgctgaagga ggtggaagtt
     7021 tataatactc ttcaccgcgc agctattgaa cttcctagtg ttcaaacccc aagtcaaatc
     7081 aagaaattct acgaaccagt tatggatatg gaaggtgtcg agattgctgg tcaaggtcag
     7141 tcagtaggca agaaaatcag cttcgatttg ccagattttt caaccaaaga aaaggtaact
     7201 ggagctgaga ttggtagtgc tactcacgaa ctcatgcaga gaattgacct cagccagcaa
     7261 ctaacccttg ctagcctaac agaaacactc aaacaagttc aaactagcca agctgtcaga
     7321 gacaagatca atcttgataa aattcttgct ttctttgaca cagtactcgg tcaggaaatt
     7381 cttgctaata ccgaccatct ctatcgcgag caacctttct ccatgctcaa acgagaccaa
     7441 aagagtcagg aagactttgt tgtccgtggt atccttgatg gctatctgct ttacgaaaac
     7501 aaaattgttc tgttcgacta caagacagac cgctatgatg aaccaagtca actcgtagac
     7561 cgctatcgtg gtcagttagc tctatacgaa gaggctttat cacgagccta ttcgattgaa
     7621 aatattgaaa aatacttgat tttactcggt aaagacgagg ttcaagttgt aaaagtataa
     7681 cttatactct tcgaaaatct cttcaaacca cgtcagcttc gccttgctgt atatatggtt
     7741 actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga cttcgtcagt
     7801 tctatctaca acctcaaaac agtgttttga gctgactgcg gctagctttc tagtttgctc
     7861 tttgattttt attgagtatt agaaaggaga cctcatgaca cttccagtta gaaaatccct
     7921 gcacgatgca gttttacagg cttcgaaagc gaatacttgg gaacaagcta ccaaggaatg
     7981 gaatgaagtt tccttgattt ttaacggtat cggccgtagc aattgtgtct gtggaaatgc
     8041 catcaaatac gcttatgaac tctttaacgg tgtcacaggc caacgcctct ttccaattgg
     8101 tagcgactgt gttcgtcatt ttcatcgatt gtcccttgac cagcaattgg aagaggaaga
     8161 aaaactgctc agaaaggttg aaaatctaac cagaaaagct cagaaaaagg aaaaaatcaa
     8221 ggtcaataaa agtgactttg acgagcgact tctaaaatgg ctctgggaaa aaggtgtttt
     8281 caaacccaat cgtggcaatc aatttgcgcc tgagagagac taccagcttt tcctagaagt
     8341 ctttcaggga ggaagttgga ccaaggcgga accaaagaaa aaggctcgga tggaagaagt
     8401 ccttgaaaag tgtatcaaac cctttttact tgggaaatcg gatgaccaac tctaccttgt
     8461 caagctaggc aaggagaaaa ttgactacga acaagaactc cgtatccagg cagagaaaga
     8521 acgcaagaag agggataaaa tcgccaagca atatgcagac aatctggttc tagccatggg
     8581 acccgcagag cgtgcttatc aagattactt tggctttaca gagaccctga ctcaagaaga
     8641 acgcaagtgg gaaaaaattc tttttggtaa aaatagagca gaacgagcta tcaaggccaa
     8701 acaataccaa aaagagctgg aaaaagacca acgaattgcc agtcaggatc caattgaaag
     8761 aaaacagaag cagacttgga tcctcaattc ctattttcgt gagcttcctg aagaaaaagc
     8821 tcgattttct agactcttat tagaatatcg aaaaagtggt gaagtaccct tttcaactga
     8881 atacctgtca gatcatctca tcgacttttt ctataaaatg aaagcctttg aatttgaaat
     8941 cgcaccagaa caagtccgag attttctaaa aaaaagcctg caggaagacc atcgctcatc
     9001 agcacaagga agctggatag aaggaattct cctcaactgc ctcaaaccat ttttagaacg
     9061 attagtgata tgagtaacac ctaccgtgta aatttcatgg taggtgttat tgtaccccca
     9121 aataatataa aacaaagtat gaaagcgcat ctcaatttta agactttttt gtaaattaag
     9181 agtataatta aggtatactg ccttttctat agataataga taatacacta atataataaa
     9241 ggtctttgta acatatataa attttatttc aaggaggaat aatggaaaag tattttggtg
     9301 aaaaacaaga gcgtttttca tttagaaaat tatcagtagg acttgtatct gcaacgattt
     9361 caagtttatt ttttatgtct gtattagcta gttcatctgt ggatgctcaa gaaactgcgg
     9421 gagttcacta taaatatgtg gcagattcag agctatcatc agaagaaaag aagcagcttg
     9481 tctatgatat tccgacatac gtggagaatg atgatgaaac ttattatctt gtttataagt
     9541 taaattctca aaatcaactg gcggaattac caaatactgg aagcaagaat gagaggcaag
     9601 ccctagttgc tggtgctagc ttagctgctc tgggaatttt aatttttgct gtttccaaga
     9661 aaaaggttaa gaataaaacg gtattacatt tagtattggt tgcgggaatg ggaaatggtg
     9721 tcttagtttc agtccatgct ttagaaaatc atcttttgct aaattacaat acggactatg
     9781 aattgacctc tggagaaaaa ttacctcttc ctaaagagat ttcaggttac acttatattg
     9841 gatatatcaa agagggaaaa acgacttctg attttgaagt aagtaatcaa gaaaaatcag
     9901 cagccactcc tacaaaacaa caaaaggtgg attataatgt tacaccaaat tttgtagacc
     9961 atccatcaac agtacaagct attcaggaac aaacacctgt ttcttcaact aagccgacag
    10021 aagttcaagt agttgaaaaa cctttctcta ctgaattaat caatccaaga aaagaagaga
    10081 aacaatcttc agattctcaa gaacaattag ccgaacataa gaatctagaa acgaagaaag
    10141 aggagaagat ttctccaaaa gaaaagactg gggtaaatac attaaatcca caggatgaag
    10201 ttttatcagg tcaattgaac aaacctgaac tcttatatca tgaggaaact atagagacaa
    10261 aaatagattt tcaagaagaa attcaagaaa atcctgattt agctgaagga actgtaagag
    10321 taaaacaaga aggtaaatta ggtaagaaag ttgaaatcgt cagaatattc tctgtaaaca
    10381 aggaagaagt ttcgcgagaa attgtttcaa cttcaacgac tgcgcctagt ccaagaatag
    10441 tcgaaaaagg tactaaaaaa actcaagtta taaaggaaca acctgagact ggtgtagaac
    10501 ataaggacgt acagtctgga gctattgttg aacccgcaat tcagcctgag ttgcccgaag
    10561 ctgtagtaag tgataaaggc gaaccagaag ttcaaccgac attacccgaa gcagttgtga
    10621 ccgacaaagg tgagactgag gttcaaccag agtcgccaga tactgtggta agtgataaag
    10681 gtgaaccaga gcaggtagcc ccattgccaa aatataaggg taatattgag caagtaaaac
    10741 ctgaaactcc ggttgagaag accaaagaac aaggtccaga aaaaactgaa gaagttccag
    10801 taaaaccaac agaagaaaca ccagtaaatc caaatgaagg tactacagaa ggaacctcaa
    10861 ttcaagga
//
LOCUS       DAVEHY010000053        10840 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVEHY010000053 DAVEHY010000000
VERSION     DAVEHY010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10840
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.053"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(201..1625)
                     /locus_tag="VUZ44_001993"
     CDS             complement(201..1625)
                     /locus_tag="VUZ44_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU0320850.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEATSKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     SLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2170..4449)
                     /gene="pulA"
                     /locus_tag="VUZ44_001994"
     CDS             complement(2170..4449)
                     /gene="pulA"
                     /locus_tag="VUZ44_001994"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU0320851.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGCNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4561..6519)
                     /gene="ligA"
                     /locus_tag="VUZ44_001995"
     CDS             complement(4561..6519)
                     /gene="ligA"
                     /locus_tag="VUZ44_001995"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU0320852.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLNYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6612..7790)
                     /locus_tag="VUZ44_001996"
     CDS             complement(6612..7790)
                     /locus_tag="VUZ44_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU0320853.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7870..8733)
                     /locus_tag="VUZ44_001997"
     CDS             complement(7870..8733)
                     /locus_tag="VUZ44_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU0320854.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKVRNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8736..10637)
                     /locus_tag="VUZ44_001998"
     CDS             complement(8736..10637)
                     /locus_tag="VUZ44_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU0320855.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQTELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3266 a         2374 c         1927 g         3273 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctagcaatg ttttagaagt agagctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta tttttctata attattatta ttttatagca aaaaaataaa accaggaaaa
      181 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
      241 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      301 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      361 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      421 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      481 aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa
      541 agcactggcc agagaagatt gccctcacgt ttgattggtg taagagcctg agcttctttt
      601 tcttgtgcat cctcaatcaa gctccaaatg aagtcggctg aagcattgtc aataacaggt
      661 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      721 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      781 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      841 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      901 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      961 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
     1021 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
     1081 gaaccttgtg ttggtggctt aaacatgacc acattccctg caatcaaggc aggtgcaatt
     1141 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1201 ggttcacgac ggacaacagc cagtttgttt ttacttgttg cctcaaaacc accaccttcc
     1261 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1321 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1381 ccaatttctt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1441 tcaactgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1501 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1561 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1621 gtcaaatttt tgtcctcctg aaaataatta agatatattt taccaaattt tcagaaaatc
     1681 acaacccttt ttgcaaaatt tttgagatta ttttcacaaa cttgattttt caaagtatac
     1741 tcaataaaaa ttaaaaaaat ccactacgtc aaggcgaggc taatgtggtt tgaagaaatt
     1801 ttcgaagagc gtgaatgagt atcatctata gtaaaataaa aaaactgaac aatttggttg
     1861 gggacagcca aaccaatttc tcacaatgtt tcagaaacaa gggtgtgcta ttccaatttc
     1921 agcctactat aactgtcata gattgctgaa acaaagtcta ggtaaaagtc ttcataataa
     1981 aaagacctcc tatcaagtgt tcaaaaactt tgataggagg tcttgttttg tgaaaatatt
     2041 tatcaaattt tctatacaag tgagctgtta gccaggttct ttctattctt tcaatttcaa
     2101 tgaatggatt ttttactaat actcataact gggaatttgt ctgtgtaaaa atagcgagat
     2161 agatggtatt tataaaacac tcaagacagc tagactaata tcatttaaaa cattatcttc
     2221 ttttgagcga ctgttggtta ccaacatagc taaatttcct gcattttcaa attgataggg
     2281 ttctgattta gcattcacaa ccaccaagag gtgttctttg ccgtgaactt catagataag
     2341 gtagccgcta tgttcaatcg cagaatgcac aaagacatga tggtaaattt catcatagct
     2401 agagtaagaa aaggcaccag tttttgtctt caatcggatg acttgacgga taaactcaat
     2461 actgtcttga cgctcattaa tcaagttcca gttcacttgg ttcacactgt caggagcatt
     2521 atagctattc atcgcacgct ctctatcatc atgggtcaac tcaccatttt caccagtcgc
     2581 aaccagtttg gtacgaccaa attcttgacc gatttccata aaggccatcc cctgcatgag
     2641 cagattcatg gctgtggcag tttcgacctt gcgcatgatt tgctctgaac tttggtctgg
     2701 atgaagggtt gccaataaat cgtgaagatt gtaattgtca tgggcttcta catagttaag
     2761 cacctgattt ggatgtgtat agcttcctaa ttcacgactt cctaggattg ctttagctag
     2821 aattggctct gtcgcagcac cactgacaaa acctgacttg atagcaccat aaacttctcc
     2881 ccctttgaca gcatcgcgct gattgtcatt aaagaaacca atatttggca tctggtaggc
     2941 attgtccttc ttggccttat cataaggggc aagacctgtt cccatatccc atccttctcc
     3001 atagaggata atgttggagt cgatttcatc caagctttga cgaatcatct gcatggtctt
     3061 gacatcatga atccccatca agtcaaaacg gaagccgtca atattatatt cctgcaccca
     3121 gtatagaaga gaatcaatca tatacttgcg aaacatttcg tgttcactgg ctgtttcatt
     3181 tccaacaccc gttccattct ggaaggtacc atctggattc atacgataat agtaatcagg
     3241 gactgttgtt tggaatggtg catcaacaac tgagaaggta tggttataga ctacatccat
     3301 aatgactcca atacccgcat cgtgataagc ttgaaccatc accttcaaat cacgaatgac
     3361 ctgagctgga tcatctggat tagttgaaaa actagtttct ggcgcgttat agttttgtgg
     3421 atcataaccc cagttgtagg ttacatttcc atcctcatcg tattctttat gacggtctgc
     3481 aattggttgc aattgaacat aattgcagcc cagcttcttg atgtaatcaa aagcagttga
     3541 ctggccgtat tggttaactg ttccagcctg agcagcaccc aagaaagttc ctcgaagatg
     3601 ttcatctaca cccgatgtag gtgatttagt caaatcacga atatgcattt cacagataac
     3661 tgccttacat ggattttcca agcgccaagt agcctccgaa ccgtgcttaa cctcgaagtt
     3721 ttcaacttgc ttttctacat ggctcagaat agctgaacgt ttgccatcag ggctggtcgc
     3781 gattgtataa ggatcacgtg tcagtgtttg gtgatgaggg aattggactt gatactgata
     3841 agccttacct accaaatctt cctcaacatc caaactccag acaccgattg tattgtcctt
     3901 atgattataa gagtagctat tgcctctttt catctcaaaa gtcttccaaa cgggtgcatc
     3961 attagcagct gattcataaa cgacaacttg cacttctgtc gctgtaggtg accagaggga
     4021 aaaatgagcc tgattgtcct ctacacggca acccaattct ccttggtaac cccaatgatg
     4081 gtcaaaacta gcactgttaa tggccttatc aaaggcaaaa ggattttgat ttttatagaa
     4141 aggactggca atagcaggat tttcagagta ataaatccta tcatcgcctt ccaaaatcca
     4201 gacctctgtt aataggggat agtgattaaa acggatagaa tattctttac tagtttgacc
     4261 tgtatgaacc acaaaattca agctttctat aacatgtgaa cttgggtgtt caaagctaaa
     4321 taaagctcca aaataatctt ctttgtaggt tagcaaatca attcgttgat cctgactttt
     4381 tacaaaggag caagtgtcat attctccatt cttacgatgg taatgaatgc gcatagggta
     4441 gttatacatt ttttattttt cctttttact ttgtttctat ttcactaata aatttttgtc
     4501 aatctcgtct caattaacag acatagtcat attctctaaa ctctgttttt aaacgatcca
     4561 ttacaaactt tctagccatg cctcatctct gacctggata ccaagttctt gtgctttttg
     4621 cagtttactt ccagcgtctg cacctaccac gacgaggtcg gtctttttag aaacactacc
     4681 tgtcactttg gcacccagac tttcgagttt acttttagct tctgagcgct tgagtcgttc
     4741 caattttcct gtcaatacca cggtcaaacc tgacaaggcc gcatccgcta ctaccgtctg
     4801 tcctttatag ttcagattga ccccagtttc tttcaattct ctgagcagaa tttcagagcc
     4861 ttctgtcgca aaataagtct gaagactttt ggcaatcacg ccacctagac tttcaatact
     4921 agccacttcc tctgaatctg cctgatacag attttcaatt gaatggaaat attgaagtaa
     4981 aagctgacta gccttgcttc caacatgacg aattcccaaa ccaaataaga gcttctcggc
     5041 agaattttcc tttgatgctt ggatagcctg atacagttta gcagcggact tttccttaac
     5101 cccctctaaa aggaggaaat cctcttcttg caaacgataa atatccgcca catccttgac
     5161 taaattagca gcaaaaagct tctcaacaat agatggacca aggcctgtaa tattcatagc
     5221 atcacgagaa gcaaagtgaa tcaagccttc catgatttga gcagggcaac gcggattgat
     5281 acaacgtagg gccacttcat cttcaaagtg caacaagtca gagttacaac ttggacagtt
     5341 tgtagggata tctagttttt cttcagaaac ccgtttggac tctaccacac gtaaaacggc
     5401 agggatgatg tcaccagcct tatatacaat gaccgtatcg tcttttcgga tatctttttc
     5461 agcaatataa tctacattgt gcagggtcgc acggctaaca gtcgtaccgg caagttgtac
     5521 tggtgttaga ttagcagttg gagttacaac accggtacgg ccaactgtcc agtcaactga
     5581 taagagttga gcttcttttt cttcagcagg gaacttgtag gctactgccc actttggagc
     5641 cttaacggta aaaccaagtt cttcttgact tgctaggtcg ttgaccttga ttaccactcc
     5701 atcaatatcg taaggcagat tttcccgttc ctgtcctact tcttggataa aattccagat
     5761 ttcatctatg ttttcagcca agattcgctt aggattgacc acaaaaccta gttgttctag
     5821 gtacttcaaa cccttttctt ggctatcacg agttgaaggg ctggcttctt gatagagaaa
     5881 cgttgcaaga ttacgcttgg caactactgc tgtatccaac tgacgcagag ttcctgctgc
     5941 cgcattacga ggattagcaa attcaggctc tccattttct tggcgcactt ggttaacttg
     6001 gtcaaaggaa gcgcgtggca tgtaacattc cccacgaact gtgatatcta gttcttctgg
     6061 caaagtcaaa gggatgtcct taacacgctt gaggttttct gtgatatttt caccaattga
     6121 accatctcca cgtgttaccc cagcaaccaa aatccccttt tcataagtca gcgagataga
     6181 taagccatcg attttcagct cacaaatata ggtcggatga gccacttcct tacgaacacg
     6241 cgcatcaaaa gcatctagct cctcacgtga aaaagcatcc tgcaaactat aaagaggata
     6301 ctgatgactg tatttttcaa aaccatctaa aaccttgcca ccaacacgat gagtcggact
     6361 gtctgctagc acttgctctg gataagcagt ttctaactcg accaactcac ggtaaaggcg
     6421 gtcatactca ctgtctgaaa ccgagggatt atcgctggta tagtactcag tcgcatagcg
     6481 attgagcaaa gcgactaact cattcattct tttattcata agaccatttt accataaaac
     6541 aagctctcct cacaaacgag aagggcggaa aaaacactta gtttgaaatt atttttgaaa
     6601 ctcaagcaac cttatatcaa tttttcaaaa tgagttcgaa cataaataaa cgatatacaa
     6661 gacaagatga taacaccact tccaattatc aggaaagaag agagatgtac acttggcaag
     6721 actgtcataa atccttttgc aataggcata aatagaatag ctaaggtaaa aattgtactc
     6781 agtactcttc caagaaattc gctctcaacc ttggtttgta cttgagtaaa aaagtgaata
     6841 ttaaaaatcg tcataaacaa ttcacaaact aaatttccag aaaaggaaag aaaagttgga
     6901 agtggtaatc ccatcataaa aactccgaca cctgtcaaag ccagtaaaat caaaagatta
     6961 taaatattag ctttaatttt actagctaga agagccccaa tgatggaacc aatagccccc
     7021 atagttaaaa tacttgcata ggctccttct gacccgtaaa gctgattcga aaagggaagt
     7081 agaaattcaa aagctgcaaa aaagaaatta acgctggaag ctaccagcaa aaggaagaaa
     7141 atttcttgct gatgccagat atagtgtaac ccatccttga tatctacaaa aatatctctc
     7201 ccagtaaaag cctttttctc ttgaactttt gcttcctctt ttggaaggaa agccactaga
     7261 acaaaagcaa tgaaaaaagt cagcgagtct agcagtagcg tcatatggag acttgcaaac
     7321 tgtaaaacaa ggaaggaaag aacaggagag ctaacaccta caacctgcaa aaccagctct
     7381 aagcgagaat tatagatcac aatctcatct ttctccacca cttcagttat gatagcttta
     7441 ttggctgtgc gagaaaaggc aaaagcaata gcctgcacaa tgttagcaac aatcaaagcg
     7501 ccaatcatcc agctatcatt ccttatgaaa gaaatagcca gacaaagaat cccacaaaca
     7561 agatctgccg tcattaaaat cttacgacga gaaaaacggt ctgaaataac tccgccaaag
     7621 ggattgacga gaatagatgt gacgagctca gaaatctgat acattcctaa aactgtctgt
     7681 cctatagtcc ccatagaagc caaccagaca ctatttccat aatcatagag catatttccc
     7741 attttattga tagccccacg gctaatcaac tgcactgcat agcgattcat attaaagctc
     7801 ctctcaaatt ttgaaactat tgtatcaaaa ccgaaaggag ctttttattt tttcccttat
     7861 ttgggaaaat taacttttga caaatttttc gtagtgttcc tgataatagg ctacttgctc
     7921 tggaagacct aacacatcaa aaatatgcat ggcctcttgc atctgcttac agccttcttt
     7981 acactgtcct ttttgatata aggcaaaacc ttttaaataa tggaaaacat tacgctcata
     8041 aagcttaata cctttgtcaa taatcttctc tgtataagcc tcaaaatagt tggcattata
     8101 aaaagaagaa tgctctaaac aatgctggta acaattgagg gccaaaatta acactaatct
     8161 cttatggcga ctaatctctt ggtaaaattc ctccctctcc ataacttctc taccaatccg
     8221 agtgacatag tctacatcgt agaaactata gaggttaccg aaaagaatca actcatacat
     8281 ggtccattct tctgttttga agagataatc tgctacctta tccaaatcat cctgcttcat
     8341 atcataactc gcatctcttt gacaaatcag accttgtagc aaaatccagt tcagctcaaa
     8401 ataaagggga gtcgtcgaac tcttagactt ttcaagttgt tctctttgaa gcttttgaaa
     8461 acctgcaata tcgtttgaat agtaaagtgg gataatctgt gccatcatag acacatgttc
     8521 atgattatga aaattcctta ccttatccat gaaattttcg attgttacat gaatgttatc
     8581 caaaatctca aagaaacggg agactgccag gtcagactcc ccaagctcaa agcgagataa
     8641 ctgagaggta gagcaggatt cgcctgctgc ttcctttaaa gaataatttc cacttgttcg
     8701 aaattcacga aatacttttc caagatgttc catctttaca cctgctctga taattcttcc
     8761 cactcaagca tagcttcttc ctgacgatgg ctgattttgt ccagctcagt ctgtaattcc
     8821 atgagtttgt cggcatcgtt tgtttccaac atttgttcag aaatggcttg gctttgactt
     8881 tctagctctt caatttcagc ttctagactt tcgatttgtc gcatgagttt gcgaacttct
     8941 ttttgacttt ctttctgggc ctgatagtca ttgactggac ttgcttcctt tgcttgattg
     9001 ctagttgaag cttcctcagt ctgactcatt tctgctgttg ctttcttctc aacatagtag
     9061 tcgtaatctc caaggtagag agttgaacca ttctcagaca attccaaaac atgagttgcc
     9121 acacgattga taaagtaacg atcatgactg acaaaaagca aggtaccatc aaagtcaatc
     9181 aaggcatttt ctagcacttc cttactatca atatccaagt ggttggtcgg ctcatccaga
     9241 atcaaaaagt tattgttttc catagacaat ttagctaaaa gcaaacgagc tttttcgcca
     9301 ccagatagca tgccgactga ttttttaaca tcatctcctg agaaaaggaa ggctccaaga
     9361 cggttgcgga tttcaacttc tggtgtcagt ttgaaatcat tccagagttc atccagcacc
     9421 gtattacttg gtgtcagctt gctttgggtt tggtcatagt aaccaacctc aacattagcg
     9481 ccaaagcgct tttctccctt gataaaagga atctggtcca caatagactt gataaaggtt
     9541 gacttgccga taccatttgg accaacgata gcgacagcat tcatcttacg aagatctagg
     9601 ttgataggtt gtgacaagac ttccccgtca taaccaatag cagtattttc aacagtcaaa
     9661 acaacattgc ccgacgtttt ttcagactgg aaggtcatgt tggctgcttt cttgccagct
     9721 tcaggcttgt ccaaacgctc cattttttct agttgtttac ggcgagattg agcacgttta
     9781 gtcgttgaag cacgaactag attgcgattg acaaagtctt ccagagcagc gatttccttc
     9841 tgttgctttt catagttttt tgcctcagta gctagctttt gctccttcaa ttcgacaaaa
     9901 cgagagtaat tccccacata gcgatccaag gaatgcttgg tcaaatctag cgtaattgtc
     9961 gcaaccttgt ccaagaaata acggtcgtgg ctgacgataa tgagggcacc gctatagttt
    10021 accaagtaat tctctagcca ggcgatggtt tcaatatcca agtggttagt tggctcgtcc
    10081 aagaccaaga gattgggctt ttcaaggagc attttggcaa gtgccaaacg agtattttga
    10141 ccaccagaaa gctcagcaat tttcatctgc cacatagact cgtcaaactt gaatccattc
    10201 aaaatcgctc gaatatcagc ttcataggta aagccgcctg cttggcgaaa attctcagat
    10261 aagtggtcgt aatctgacat cagtttatcc aattcatcgc cagacttttc acccatctcc
    10321 aactccatct gacgcagttg tctctccgtc cgacgcaaat tattaaagac atgaagcatt
    10381 tcatcgtaga tggtattttc agactcaaaa cggctatctt gggctaggta agacagagaa
    10441 atatcttttt tcttattgat ttctccgcta gttggctcct cttctccaac taaaatcttc
    10501 aaaagagtag acttacctgc accatttttc ccaacaagag caatccgatc tcgttcatca
    10561 acctgcaggt tgatattatc gaaaagaacc tctcctgcaa aagaacgttc aattttatta
    10621 gcttgtaaaa taatcataag agtagtatag catgtttccc taaggcattc aagataatcg
    10681 taagtctttt agtacaactt ttataacata aaataaacta aattatgtat attttatatt
    10741 agattccttc actatcttgt tggattttct aaccagctaa tcttgtttca aatagttatc
    10801 gcacaagtct attatttaat tcttttcatt atttacgtac
//
LOCUS       DAVEHY010000054        10576 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVEHY010000054 DAVEHY010000000
VERSION     DAVEHY010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.054"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            57..861
                     /locus_tag="VUZ44_001999"
     CDS             join(57..425,427..861)
                     /locus_tag="VUZ44_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU0320856.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQIPRKSSKLKPLIAEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            910..1374
                     /locus_tag="VUZ44_002000"
     CDS             910..1374
                     /locus_tag="VUZ44_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU0320857.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            1532..1957
                     /gene="lacA"
                     /locus_tag="VUZ44_002001"
     CDS             1532..1957
                     /gene="lacA"
                     /locus_tag="VUZ44_002001"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU0320858.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1988..2503
                     /gene="lacB"
                     /locus_tag="VUZ44_002002"
     CDS             1988..2503
                     /gene="lacB"
                     /locus_tag="VUZ44_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU0320859.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            2514..3443
                     /locus_tag="VUZ44_002003"
     CDS             2514..3443
                     /locus_tag="VUZ44_002003"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU0320860.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            3445..4425
                     /gene="lacD"
                     /locus_tag="VUZ44_002004"
     CDS             3445..4425
                     /gene="lacD"
                     /locus_tag="VUZ44_002004"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU0320861.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4659..5495
                     /locus_tag="VUZ44_002005"
     CDS             4659..5495
                     /locus_tag="VUZ44_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU0320862.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5531..5848
                     /locus_tag="VUZ44_002006"
     CDS             5531..5848
                     /locus_tag="VUZ44_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU0320863.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5850..7544
                     /locus_tag="VUZ44_002007"
     CDS             5850..7544
                     /locus_tag="VUZ44_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU0320864.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7759..9165
                     /gene="lacG"
                     /locus_tag="VUZ44_002008"
     CDS             7759..9165
                     /gene="lacG"
                     /locus_tag="VUZ44_002008"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU0320865.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9255..9467
                     /locus_tag="VUZ44_002009"
     CDS             9255..9467
                     /locus_tag="VUZ44_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU0320866.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(9746..10507)
                     /locus_tag="VUZ44_002010"
     CDS             complement(9746..10507)
                     /locus_tag="VUZ44_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU0320867.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         3402 a         1818 c         2131 g         3225 t
ORIGIN      
        1 tccagtattt gacaatatta gacttcctgc gaaacaaaat atggtatagt agttccatga
       61 attatgaagc aagtaaacaa ctaactgatg cacgatttaa gcgtcttgtt ggtgttcaac
      121 gcacgacttt tgaagagata ttagctgtat taaaaacagc ttatcaactt aaacacgcaa
      181 aaggtggacg aaaacctaaa ttaagcctag aagactttct tatggccact cttcaatatg
      241 tgcgagaata tcgaacttat gaagaaattg cggctgattt tggtatccac gaaagcaact
      301 taatccgtcg gagccgatgg gttgaagtaa ctcttgttca aagtggtgtt acgatttcaa
      361 gaactcctct cagttctgag gacacggtaa tgattgatgc gacggaagta caaatcaatc
      421 gccctaaaaa aacaattagc gaattattct ggtaaaaaga aatttcacgc tatgaaggct
      481 caagcgattg tcacaagtca agggagaatt gtttctttgg atatcgctgt gaactattgt
      541 catgatatga agttgttcaa aatgagtcgc agaaatatcg gacaagctgg taaaatcttg
      601 gctgacagtg gttatcaagg gctcatgaag atatatcctc aagcacaaat tccacgtaaa
      661 tccagcaaac tcaagccgct aatagctgaa gataaagcct ataaccatgc gctatctaag
      721 gatagaagca aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat gttttcaaca
      781 acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgagtgc tggtattatc
      841 aatcatgaac taggattcta gttttgcagg aagtctaata aagaaactag caaggtcagg
      901 ccttacttta ttggtggaca tccaggattt aattgtcttc tacttgatga tgaagtctat
      961 gaagattatt atctagagtt tgagaaagaa gagatttgct ctgttccacg tcctttccca
     1021 gaaacaggta tgttggattt ccaagataga agtccatggc tagagggaca aaaagaaata
     1081 gatcttagtt atgatctttt cagcacagat gcagtgactt tggatgaatt gcaatctcga
     1141 acaattgccc ttcgttctct taaacatgat aagggattga aagtgcattt tgcagaattt
     1201 ccaaacctca tcatctggtc aactttgaac aagggacctt tcattacctt tgaaccatgg
     1261 tctggcttgt caacattcct tgaagaagga gatcatttag aagataagaa gaatgtttgt
     1321 ctcttagaag ccaatcaggt tgaagaatta gggtttgaga tagaagtttt ataaaaaaag
     1381 taaaaaataa ataacaaaaa caaacacaaa ctgttgactt cttcaaacaa tagtagtata
     1441 ttatgtttgt gaggactaat tgactgtttt ttaaagacag ccaatacact gctggaatcc
     1501 agcatagaaa aaataaaaag gagtatacaa tatgtctatt gttatcggtg cagatgctgc
     1561 aggtttgaga ttgaaagaag ttgtgaaaga cttcttagaa aaagaaaact tccaccttgt
     1621 ggatgttaca gctgaaggtc aagactttgt tgatgtgact ctcgctgttg ctgcagaagt
     1681 aaacaaagaa gaacaaaacc ttggtatcgt gattgatgct tatggagctg gtccatttat
     1741 ggttgcaact aagatcaaag gaatggttgc tgcagaagta tctgacgaac gttcagctta
     1801 tatgactcgt ggccacaaca actcacgtat gatcactatg ggtgcacaac ttgttggtga
     1861 tgaattggct aaaaacatcg ctaaaggatt tgttaacggt aaatacgatg gtggacgtca
     1921 tcaaatccgg gtcgacatgt tgaacaaaat gggctaatta gattacagta agaaaggtaa
     1981 gttaaaaatg agaattgcaa ttggatgcga ccacatcgta acagatgaaa aaatggcggt
     2041 ttcagaattt ttgaaatcaa aaggatatga agtcattgac tttggtacat atgaccatac
     2101 acggactcac tacccaatct ttggtaaaaa agtaggggaa gctgtaacta gcggccaagc
     2161 tgatcttggg gtatgtatct gtggtactgg tgttggtatc aacaacgctg taaataaagt
     2221 tccaggtgtt cgttctgcct tggttcgtga tatgacaaca gccctttatg ctaaagaaca
     2281 attgaacgct aacgttatcg gctttggtgg taagattact ggtgaattgc ttatgtgtga
     2341 tatcatcgaa gctttcattc atgctgaata caaaccatct gaagaaaaca agaaattgat
     2401 tgcgaaaatt gaacaccttg aaagtcacaa tgctcaacaa acagacgcaa acttctttac
     2461 agaattcctt gaaaaatggg atcgcggaga ataccacgac taagaggtga cctatgattt
     2521 taacagtcac aatgaaccca tccattgata tttcctatcc cttggatgag ttgaagattg
     2581 atactgtcaa tcgtgtggtg gatgtaacca aaacggctgg tggtaaggga ctcaatgtta
     2641 cccgagtact ttcagaattt ggcgattctg ttcttgctac tggtttagtg ggtggcaaac
     2701 ttggtgagtt tttggttgaa catatcgata atcaagtaaa gaaagatttc ttctcaattc
     2761 agggagaaac tcgtaactgt atcgctattc tccacggaga caaccaaaca gaagttcttg
     2821 aaaaaggtcc tgaagtattg gaacaggaag gtcaagactt tttggaacat ttcaaaaaac
     2881 tcttggagtc agttgaagta gtggccatct caggtagtct gccagctggc cttccagttg
     2941 attactatgc gagcttggta gaacttgcta atcaagctgg caagcctgta gtcttggact
     3001 gctcaggtgc agcacttcag gctgttcttg aatcacccca taaaccaaca gtcatcaaac
     3061 caaataatga agaattgtct cagcttcttg gaagagaagt ttctgaggat ttggatgaat
     3121 taaaagaagt acttcaagaa cctttgtttg cagggattga atggattatc gtttcacttg
     3181 gtgccaacgg tacttttgcc aaacatggtg acactttcta caaggtagat attcctagaa
     3241 ttcaggtggt aaatcctgtt ggatctggag actctactgt ggcaggaatt tcttcaggac
     3301 ttcttcacaa agaatcggat gcagaattac tcatcaaggc aaatgtcctt ggtatgctca
     3361 atgctcaaga aaaaatgact ggtcatgtca acatggccaa ctatcaagct ctatatgatc
     3421 aattaatagt aaaagaggta taaaatggct ttaacagaac aaaaacgtgt acgcttagaa
     3481 aaactttctg atgaaaatgg tatcatctca gctcttgcat ttgaccaacg tggtgctttg
     3541 aaacgcctca tggctcaaca ccaaacagaa gaaccaactg tggcccaaat ggaagaactt
     3601 aaagtcttgg tagcagatga attgactaaa tacgcttcat ctatgcttct tgaccctgag
     3661 tatggacttc cagcaactaa agctcttgat gaaaaagctg gtcttctcct tgcttatgaa
     3721 aaaacaggtt atgacacaac aagcacaaaa cgcttgccag actgcttgga tgtttggtct
     3781 gcaaaacgta ttaaagaaga aggtgcagat gcagttaaat tcttgcttta ctatgatgta
     3841 gatagctcag acgaactcaa tcaagaaaaa caagcctaca tcgaacgcat cggttctgag
     3901 tgtgtggctg aagatatccc attcttcctt gaaatccttg cttacgatga aaaaattgcg
     3961 gatgcaggtt ctgtagaata cgcgaaagta aaaccacaca aagttatcgg cgctatgaaa
     4021 gtcttttcag acccacgctt taacattgat gtcttgaaag ttgaagttcc tgttaacatt
     4081 aaatatgttg aaggcttcgc tgaaggtgaa gtagtttata cacgtgaaga agcagcagcc
     4141 ttcttcaaag cgcaagatga agcaacgaac ttgccataca tctacttgag tgctggtgta
     4201 tcagctaaac tcttccaaga tactcttgta tttgctcatg aatcaggtgc aaactttaac
     4261 ggagttcttt gtggccgtgc tacatgggca gggtcagttg aagcttacat caaagatggt
     4321 gaagcagcag ctcgcgaatg gcttcgcaca actggatttg aaaacattga tgagctcaat
     4381 aaggttcttc aaacaacagc gacttcatgg aaagaacgtg tgtaagaaag tcctcctagt
     4441 ttaggaacat gaatctaaaa aaatttaaaa aaagttgtat gtaaaggttt acaaaataac
     4501 ttacttgtgc tatacttaaa tcacaagtta atacaaggtg agtgttacta agtaatatta
     4561 ggcatgatca caggtgaatt agaaatcagc tgattttcta gttcatttgt ggtcattttt
     4621 tgtactcata tacctttaaa atataaaagg aggttgacat gtatcgaatt ctaaatccaa
     4681 tgaatcacaa tgtctcgctt gtcagaaatg ataagggaga agaggtgatt gtaattggta
     4741 aggggattgc attcggaaag aagaaggggg atttgattgc tgaaaatcag gttgagaaaa
     4801 tctttcggat gaagaccgaa gagtccagag aaaactttat ggctcttctc aaagatgttc
     4861 cgcttgattt tatcacagtg acctatgaaa tcattgataa gctatcaaag aaatatcatt
     4921 atccgattca agagtatctc tatgtaacct tgacagatca tatttactgt tcttatcaag
     4981 ctctaactca aggaaggtac aaggatagta atctgccaga tatttccgct aagtatcctg
     5041 tcgcttttca aatcgcaaat gaagcttttg aaatttaccg tcagaagcta gcagatcatt
     5101 ttcctgagga cgaaattatt cggattgctt atcatttcat taatgctgaa ggtgaaaatg
     5161 aagtggaact tgtggagtcg attgataaga ggaaagaaat tctcaggaat gttgaagaag
     5221 ttttaacgga ctatgcaatt caacgaacta aaaagaataa ccatttctat gatcgcttta
     5281 tgatccattt gaattatttc ttggattatt tagacagatc tagagatgat aaccaatcac
     5341 ttctggatat ggaagatcat attaaacaat cctatccaaa agccttcgag attggttcca
     5401 agatctatga tgtgattacg caacatacgg gtcttgattt gtataaaagt gaacgagttt
     5461 atctagttct acatatccaa cgtttattgt cataaaaatt tatttaaaac tatataagga
     5521 gaattctatc atgaatagag aagaagtaac attgttaggt tttgaaatcg tagcctatgc
     5581 tggcgatgct cgttcaaaac tattggaagc cttgaaggct gctgaagctg gtgattttga
     5641 aaaagcggac gctctggtag aggaagctgg tagctgtatt gcagaggctc accacgcgca
     5701 aacaagtcta ttgactaagg aagcttctgg tgaggactta gcgtatagtg tgaccatgat
     5761 gcatggtcaa gatcacttga tgacaactat cttgttaaaa gacctaatgc accatttaat
     5821 tgaactttac aagagaggag ttaaataaaa tggataagtt aataattttt attgagaaag
     5881 gaaagccttt ctttgaaaaa ttatcgagaa atatatactt aagagcgata aaagatggtt
     5941 ttatttccag tatgccagca gtattattct caagtatttt tatactaata gctgctgtgc
     6001 ccaatatttt tgggtttaaa tggtctgatg aacagttagc ttttattttg aaaccttaca
     6061 actactcaat gggaatttta gctctcttag tagctgggac aactgcaaaa tcgttaacag
     6121 attcagttaa tacacgtagt atggagaaaa ccaaccaaat caactacatg tcaacttttt
     6181 tagcagctgt tgttggattg ttaatactgg cagctgatcc aattgaaggt ggatttgcta
     6241 atggtctttt aggtactaga ggattactta ctgcattttt ggcagctttt attacagtaa
     6301 atatctataa agtatgtatt aaaaataatg taaccattag acttcctgaa gaggttccac
     6361 caaatattgc acaagttttt aaagatgtta ttccgtttgc cttatctgtt ctttcaatat
     6421 atggattgga tttaattgtt agaaatattt ttggtacaaa tgtagcagaa tctgttggta
     6481 aaatattagc tcctctattt tcagctactg atggttatat cggtttagct attgtatttg
     6541 gtgcttatgc tttcttttgg tttgttggaa ttcatgggcc atctgttgta gaacctttaa
     6601 ttgtagctat cagttatgca aatatagaag ctaatgttca gcttgtgcaa gctggtatgc
     6661 acgcagataa aattttaaat ccagttactc aaacttttgt tgtaacaatg ggtggtactg
     6721 gtgcaacact agtagttcca tttatgttta tgtggttatg taaatcaaaa agaaatagaa
     6781 ttgtcggacg tgcgtctgta gttcctactt tctttggcgt aaatgaacca atcctatttg
     6841 gtgctccaat tgttttaaat cctatcttct ttattccgtt tgttactgct cctattatca
     6901 atgtttggat tatgaaattt tttgtagatg ttctacaaat gaatagtttc agtattattt
     6961 taccttggac aacacctgct ccaattggta ttgttatggg aacggcgctg gctccattgt
     7021 cattcgtctt ggctataact ttaatcatta tcgacacttt aatctattat ccatttgtta
     7081 aagtttatga ccatcaaatt ttagaagaag aacggaaagg aaactcttca tctgaattga
     7141 aagaaaaagt tgctgcaaac ttcaacactg caaaagcgga tgctattctt gaaaaagcgg
     7201 gtgtcgatgc agcacaaaat accatcactg aagaaacaaa tgtcctcgtt ctctgtgctg
     7261 gtggaggtac aagtggactc cttgcaaatg ctttgaataa ggcagcagca gaatacaatg
     7321 tccctgtgaa agcagcagca ggtggctatg gtgctcaccg tgaaatgttg ccagagtttg
     7381 atcttgttat ccttgcccct caagttgctt caaactttga agatatgaag gcagaaacag
     7441 ataagctcgg tattaaactt gctaagacag aaggcgctca atacatcaaa ttaactcgtg
     7501 atggaaaagg tgccctagca ttcgtacaag agcaattcga ttaaggctag agactctgaa
     7561 acagtctccc atcgttacgg aaatcgctat ggcgaatttc ctaatcgcct tattaattcg
     7621 tcggtaaaaa gatatcgttt ttacctcctc atgtcacaat tcagtgactt ggcacaagaa
     7681 gtgagatgga gaagcatggc tcactgactc ctctcctctc acttttactt tatttaaatc
     7741 aagaaatagg tgaaaaaaat gacaaaaaca cttccaaaag actttatttt cggtggcgca
     7801 acagctgctt atcaagcaga aggtgctaca catactgatg gaaaaggacc agttgcttgg
     7861 gataaatatc ttgaggataa ctactggtac actgccgaac cagctagtga tttttacaat
     7921 cgatatccag ttgacctcaa gctagcagaa gagtatggtg tcaatggtat tcgaatttct
     7981 attgcttggt cacgtatttt cccgactggt tacggccaag taaatgctaa aggtgttgag
     8041 ttttatcata atttatttgc agagtgtcac aaacgtcatg ttgagccctt tgtaactctt
     8101 catcactttg acactccaga agctctccac tcaaatggag acttcttaaa ccgtgaaaat
     8161 atcgaacatt ttgtagacta cgctgccttc tgttttgaag aatttccaga agtaaactat
     8221 tggacaacct ttaatgaaat tggaccaatc ggtgatggtc aatatttggt tgggaaattc
     8281 cctccaggta tccagtacga ccttgccaaa gtctttcaat cacaccacaa tatgatggtg
     8341 tctcatgcac gcgcggtaaa attgtacaaa gagaaaggct ataaagggga aattggtgtt
     8401 gttcacgccc tgccaactaa atatcctcta gatcctgaaa atccagcaga tgttcgtgca
     8461 gctgagttgg aagatatcat ccacaataaa ttcatcttag acgcaactta tctaggtcgc
     8521 tattcagctg aaaccatgga aggtgtcaac catatcttat cagtcaatgg tggtagtttg
     8581 gatcttcgtg aagaagattt tacagcatta gaagctgcaa aagacttgaa tgatttccta
     8641 ggaatcaact actatatgag tgactggatg gaagcctttg atggagaaac tgaaattatc
     8701 cataatggta aaggtgaaaa aggaagctct aagtatcaaa tcaaaggtgt tggtcgtcgt
     8761 gtagctcctg actatgtacc acgcacggat tgggattgga ttatctaccc tcaaggtttg
     8821 tatgaccaaa tcatgcgcgt gaagaaagat tatcctaact ataagaaaat ctacatcact
     8881 gaaaatggtc ttggatataa agatgagttc gttgataaca ctgtttacga tgatggtcgt
     8941 attgattacg tgaaacaaca cttggagatc ttgtctgatg cgattgcaga tggagctaat
     9001 gtaaaaggtt acttcatttg gtcattaatg gatgtcttct catggtcaaa cggttatgag
     9061 aaacgttatg gtctcttcta cgtagatttt gaaactcaag aacgttatcc taagaaatca
     9121 gctcactggt acaagaaagt agcggaaact cagattatag actagtagaa ttagtcatta
     9181 gatatagaat tttagtgagt caaaaagatg ttcaaagatt ttatccaatc tatttatgaa
     9241 aaaaagttta tattataaat ttcgaaaaat gctctcaaat accgtgtttg acgagtgaag
     9301 aattgaaaag tcttggaaaa tggtatgtct cgactggtaa agaatggatt tgtcattcag
     9361 atgatgagct ggaagaattt aaaaatctat ttttaaattt tatcaatcct gaagaatggg
     9421 atactatctc ctttgattca gattttatgc cgtttcaaca atcgtaacca atttctcaaa
     9481 aaagttaaat cttatattta gtactctgta aaactcttat ctaatcacgt tgcttatact
     9541 caatgaaaat caaagagcaa ctttaaacta ggaagcgagt cgcagatttc tcaatgtata
     9601 gctttgagga attgggcaaa aagtctttga tatagaaaaa agcatagtat caggtgtttc
     9661 aacacctgat actatgcttt ttattgtggg aagatttact ttttttcttc tgaaattgag
     9721 ttgttaccca ggctctttca gtttattaag gcttgatgac tttaatgtgt ttagatagct
     9781 taaaaaggat tgaatcactt agtttagaat ctgaaacaat agtatcaaga tttgatatat
     9841 tataaaaagt ataaaaatca aacttattga acttactatg atctgcgagt aaatattttt
     9901 tattagaatt atttaaagcg atgcgttgag cctctccctc ttcctcgcta aaagtagcta
     9961 gagctccgtt ttgaatacca ttacagctaa cgaaagcttt agaaaattgg agattagaga
    10021 gattttgtag agtcaatgtg ccaacaaaag cacctgtaat atcgcgataa tttccaccta
    10081 tcaaaatcaa atctgttaat tttcgttcgc ttaaaatcag aaaaacaggt agactgttgg
    10141 ttacgacgcg gatattgtca ataggcaact cacgcgcaaa aaactctaat gttgttcctg
    10201 gtccaatgaa aatagtttct ctttcttcta ctagactgcc tgcaaaatgg gctatttctt
    10261 gtttttctgc cgtttggagg gcttgttttt caatatttga tcgctcatta gtcaaaaggg
    10321 agttggttcg aagtttttca gctccaccat gcacacgaat cagcaaatct ttatcagcta
    10381 attcctgtaa atagcgcctt gcagtcatat ctgaaacggc tatttcgtcc ataatctgtt
    10441 taactgttat ggttccttta ctatttacta tctctaaaat tttggttaat ttttcttgtt
    10501 tgagcatatt atcacctcgt ttcctactac tatcttacca taaacaaact catcattcaa
    10561 atacaaaaac aacaaa
//
LOCUS       DAVEHY010000055        10219 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVEHY010000055 DAVEHY010000000
VERSION     DAVEHY010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.055"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            660..1031
                     /locus_tag="VUZ44_002011"
     CDS             660..1031
                     /locus_tag="VUZ44_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEU0320868.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            1039..1251
                     /locus_tag="VUZ44_002012"
     CDS             1039..1251
                     /locus_tag="VUZ44_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320869.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            2133..3191
                     /locus_tag="VUZ44_002013"
     CDS             2133..3191
                     /locus_tag="VUZ44_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320870.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIIKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            3505..4482
                     /locus_tag="VUZ44_002014"
     CDS             3505..4482
                     /locus_tag="VUZ44_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320871.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     SGIAVFYKESQTTNNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            4953..5327
                     /locus_tag="VUZ44_002015"
     CDS             4953..5327
                     /locus_tag="VUZ44_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU0320872.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            5535..6437
                     /locus_tag="VUZ44_002016"
     CDS             5535..6437
                     /locus_tag="VUZ44_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320873.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLMKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            6493..6825
                     /locus_tag="VUZ44_002017"
     CDS             6493..6825
                     /locus_tag="VUZ44_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU0320874.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            6822..7550
                     /locus_tag="VUZ44_002018"
     CDS             6822..7550
                     /locus_tag="VUZ44_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320875.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLLLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            8685..9188
                     /locus_tag="VUZ44_002019"
     CDS             8685..9188
                     /locus_tag="VUZ44_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320876.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLCEFIGDIFYSKITSCC
                     IVAKDLSKNTMKLDVIFFEDRNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            9474..>10219
                     /locus_tag="VUZ44_002020"
     CDS             9474..>10219
                     /locus_tag="VUZ44_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEU0320877.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPQAVEKSSSE
                     KKYDEAKAKSDAAKKNYDEAKKKAAEAQKKYEDDQKRTEAKAEKERKASEKIAEATKE
                     VQQAYLAYLQASNESQRKEADKKIKEATQRKDEAEAAFATIRTTIVVPEPSELAETKK
                     KAEEAKAEEKVAKRKYDYATLKLALAKKEVEAKELEIEKLQYEISTLEQEVATAQHQV
                     DNLKKLLAGADPDDGTEVIEAKLKKGEAEL"
BASE COUNT         3470 a         1294 c         1881 g         3574 t
ORIGIN      
        1 taaaattcac tttagttact tgacagttat tatattttcg ctcataatat agataaaagg
       61 atgggatagg agtttaaaaa tttgaaagcg ctatccataa tcgtaacgca taattttctc
      121 cttttcgtga aaaaagttaa cgtaattttg aaatgagctt aataagaggt actatgtagg
      181 tagaaaataa agataggaga aaaagtatga ataaaaaaat attttgtatt ctagtatgta
      241 ttatatcatt gattagtcta gctataatct ttccatgggg ctggtcgata taatgtaagg
      301 gagcttgagt tgttagtaga ggataaaatg ttaagagtaa tagtagttat tcaatcttta
      361 gtaataatac tgcttgctgt tgctttatta ttatctcgga aaaactttga ttcgttaaat
      421 gttgttctta taatgatgat cgtatcacaa ttgttgttat tagtatattt gataaaatca
      481 gggaatcagt gattagctgt tatttgaatt aagtaaactg ttaagcttca agcagtaact
      541 ggttttaaat atttaaaata agataaagga aggaagtcta atttaggtaa ctaaacaaag
      601 cctgcgatca cttgttagga aaccatccta agcatgctta ataaaaaagg agaaaataaa
      661 tggaacttgt attaccaaat aattatgttg tgattgatga agaagagatg atgtaccttg
      721 atgggggggc tatatatata cccaggtggg caattacagg agccattact ggtgcagcat
      781 atgcagcatt agcagcagca ggaggtggag gccttcaact agttcttgca tcttatggat
      841 tacgctccgc actggtagct gggattgtta aaggtttagg agtattagga attcatattg
      901 gaaatgcttt tgcaaatact gttattagaa gtattgcatc tgctggaatt ggtgctggag
      961 ctgattggat ttttaccaat attattgatg gctgggatgg gcgacgtgat aatcaattga
     1021 gaataggata ataatcttat gttgattgtt ttaatttcag ttattgttgc attcctgtat
     1081 cataaaatta cagagtatgt caacaacagg aaaattgata ttgttatttt tctatcattg
     1141 ctgatttctc attttatttg gaattactat tttttaccaa ttgaaatatt gatagcaatc
     1201 agtggagcaa atttattatt aagtttttta aaaaaattac agattaaata atattattcc
     1261 atatgacata tcaactaggt cattagattt tattgaagat ataaattaaa aacgaggttg
     1321 ggaaaaaact caatttgaaa gtgagattga gtaaatcttt ctatctatat aacgtatatc
     1381 atcaatattt ttgaacacct gataatatgc acttttctta ttttaaagat tttttgcctt
     1441 tcttcatttc ttgaatgaat cggagagatg actttattta ggtgtttgac attactatag
     1501 ataggattta gcagtactaa tatgaactca tattataggt gcagacttaa attttggaag
     1561 caagctaaag gatatcttat ctaggtaact aagtgctata acaagatata ttggtggagt
     1621 tagtatggca actattacta atgctcttaa tattgcggct actgttgctg aagtcttctc
     1681 attaggagga gccattgcat atggtttaga tatcgtagac ggtaaatttg atgggtattt
     1741 atgggcgtaa aattatagct atgaaacatt tttttgcagg aattggtgaa attcattttt
     1801 tgttattttt attatatcta agcatgtctg ctagtccaat tattggacta gtgattggat
     1861 atactaaaat aaatctaata aattctatta ttatagctct tggtatgata ttggtattaa
     1921 ttttggtatt atcaagagtg tatagaaaat atttttatag agacgatgat gactaaagtt
     1981 tttatcaata atttgggctc cttgtcaact gtagtgggtt gaagaaaagc taacgtctgg
     2041 ggaaggggtt aaagctttgc tttatcaaat attgacttac agagttgctc tattgtattg
     2101 atgtattctt agtaaataat atggtgtttt gaatgaaaga tgatcagaaa tatttattag
     2161 cgggacttta ttcgcttcta gttgcaatat tttattttcc attgattgag tccaagggga
     2221 tttttgtaag tatattgatg gcggttttac ttttatattt aatatacttc attgcaacag
     2281 tcattcatat tgtgataatt aagtttataa taaaaaaatc ttttaagtat ttggttctat
     2341 atccatttac ttatgatggg agctggagat ttcaacctat aaacttactc tactttccag
     2401 aaatggtgag agatgtcatt ccgattaatt tagttcaaga atattgccaa ggacaacctt
     2461 acggactgtt aaaaaagatg ctgaaaagaa ttcgattgtc acgagagata tctttactcc
     2521 tggctaccat tatcgtctat ttttttacgc atagaattct acctctttca gtatttacgt
     2581 tcatattttc ttacatattg ctatttgcac aatcttattt gggtggtaat accgcttgga
     2641 ttggaaatag aagattaata atagatgatg aatttgaaaa aatcttgctt tcaaaaagtt
     2701 atataaaaga aatatcatct gcacgatact cagaatactt gacatgtgaa tacaaaaacc
     2761 ttacaccaat catattgtta gctatttttg aaaatttgct tgactcctac ttgcttcaga
     2821 atcagagtga ggttgactta gatatttttt ataaagtttt acctttgctt tataaagaaa
     2881 aatatactat gggattcaat tactttgtaa gtttaaatta tttactatat aaggttggat
     2941 ttttgggaat catttacgat aatgaagcat taagagattt gtcaaaacaa tatttaaaca
     3001 aaaatatttc ggaattacaa gatggttctt tcgagggcgg tatacaagat gctgttgctt
     3061 ctaaacaaat agtagttata aatgaattta tagcttgttt aaattccaga tgcgtgccat
     3121 cccaatatga tagatttttt tataaagata gaccttatat tttttccaga aagagtccta
     3181 ttaaggggtg aaaatttgtt acatttggat taacaagtgt cctagggatt agaaataact
     3241 ctagtatagc tagatatttt tgagtaacta gaaatatcat taggctaccc atatgattgc
     3301 cagaaaagat ggctgatgaa tcttatttat actgttgcag taggcgttgt ctaggataaa
     3361 taagctatct tgatggggga gattggaata attttagtag aaacattaaa ggattatgga
     3421 caagtagcgc aggattaggt gatgcaatgt gctaagttgg cttggtgtta gcagtagtat
     3481 tatttaacaa tggaaagtag actaatgaaa aataagcgtt atttttttga cacaatttta
     3541 ataattttac tgcttataag cacgatattt tgtgtcagcc cagtatttat aaaattggac
     3601 atcttaggaa ctccctctca tgccatctta acctttgtat tggcgatacc gttattctat
     3661 attttgtctc aatgcttaca tactttgcta ttactagttt cctcaatctt ttgtaaatta
     3721 agaccaattt atttttattt tatatttgtg atcattatag gagctaggaa atactatcga
     3781 attctctttc accaactaat gggatttagt tcaggaatag cagtgtttta taaggagagt
     3841 caaacaacta acaatctgtt taaattttac tacttcttgt actttacaac actaatttca
     3901 tactattttt tctttacttt tgtgtatgac aaaccgttgc ttttgcctct tattccgttt
     3961 tctattatca tagcattagt acaaaaactt tatagaattg agaatcaaca attatttctg
     4021 ttaaaatcaa aggtactaac aatactggaa tctaagaggg attgtgagtt taatcttcag
     4081 gattatcatg aaatttggaa attgcaatca aaatctgagt tgccatgcgt ggctttatct
     4141 tatatcagtt tgatcaagcc atatctttca gagagcgtgc gtgaacaaat tgatttatta
     4201 gaagttaagc gatttaaaaa aataaatcat ccaatatcac tttatggtat gttggatgtt
     4261 ataaaattaa atctatattt acggcattat aatgaaaaaa ataaatatga atcaatgtta
     4321 aataaaattt tagaggtaag accagacttt gttttaatcg agcagaatat tgatgatagt
     4381 ttaaatagct cgcaaccatt atctttatct ttagccattt cagaaatcca acttttgctt
     4441 gaagtgtata tggggatcaa acatgtttca attaggagat aaaactagaa taacatttgc
     4501 tattataggg gcaagttgca tattagtcag tatgtatctt attccactta ttaaaactga
     4561 gaataaattt tgggaaatac ttttatttat attaggtgta ttgctaattg gaattgcgtt
     4621 actaagtcaa aaaaaataaa ttttgtgtta gtgaatacgt aattattact attgactgtt
     4681 ttatggtgga aagcatccat agctttttgt aaaataatct gattggctaa tatttgcagt
     4741 aggtgttgtc tatgataaag aaacctatct tgattggatt ttagaactgt taagtttcaa
     4801 gcaataattg gttttaaacc ttaggtaacc tataaaaaca aataaggtag agaaaggata
     4861 tcttatttag gtaactaagt actataaaca cagtcgacaa tcacttgtta ggaaaccatc
     4921 ctaactatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca aataattatg
     4981 ttgttcttga gcaagaagag atgatgtatc ttgatggggg attttctatt ccgagatggc
     5041 ctgttgcaac agccattaat atagctttta atggtgtttt aggtggagga gcaatcagtc
     5101 tagttagaaa ttatattcgt aattatggtt tgcggcgagt tacaagcgca attgctggag
     5161 cagctgcaag atatgttggg gtacgagttg caaatagagt ggcaggattt gcactgtctg
     5221 ctattaatgg atttgcagct tggatgtcaa ttggcgatgc tattacaaca atctgggcca
     5281 acaatgatgt aaataggaga gacccaaatt taaacgcctt gtggtaacta gatatgggta
     5341 ttaaaatgga aaaaattttt gttattattt tttttgtatg tctatttata tcatccataa
     5401 cttttttagc ctatgatttt gttagcgaag aaataaaaaa gttgattatt tggatgaatg
     5461 tcgttttttt gattttaatc atagcaatga taatttatcc aaaattaaga aaatgataag
     5521 gacactgtaa aattatgata cgtaaactaa tcattttttt attaatgctc cctctttttg
     5581 tcttgtggct agagttgcat ttgttagtga gtaacttgca attgaatcta gaaattcccc
     5641 ttgattttgt ggttagtacg agtcttgctt tctgtagttt gattttatca aaaatagttt
     5701 tagacatact atacgcattg aaagatttgt acaagaaaga agctcttatt acgatttttc
     5761 cttttatttt tataggcagg aagaaagtaa atgtgaggtt ctcgccctat ttttcattcc
     5821 atcgtaaaag tttgtcgcct gatgatttaa gatctaggat tatatggagt tttattcttg
     5881 aaattgctat tattctagta tttattttaa aaattccttt tgcaatcatc atgcttacta
     5941 caatattttt ctggactata atggatatca atcatctcgt ttttaataag acggaatttc
     6001 tttttaatca aaataaatgg gaaaaagaag attcgtttga aagcgatttg atgaaaacgt
     6061 taaaggataa gatacaaaaa tcagagctaa gttattctga cttaatgtct cttcagctgt
     6121 atgatgcgat gaaccaatcc acctttttaa cggatagtga actttttgag gatattttga
     6181 aaaaaatcga agattctcat aacacccttc tgtgtacagg tcttgtcgag ttactgctgt
     6241 atgaaatgtc tattagtaac aataacaact ggtccaacaa ggttgataaa attaggatac
     6301 acctcatcag aatcaatcaa ttagattttt tctattatac aagttggtta aggcaaaatt
     6361 ttgatttctg tatgaataga gagtatcata aaatgaaatc tcggaaatta ttactgagta
     6421 ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa tgaaacaatt tcaactaagg
     6481 aggagaaaac aaatggaact tgtattacca aataattatg ttgtgattga tgaagaagaa
     6541 atgatgtatc ttgatggggg agcttattta agcaagcgtg cttgtcaagg aatttgcgta
     6601 gctttagcta tgagttcagg aacttttata gcattagctg gagctgcagt tttaaccaaa
     6661 aaactaataa actatattaa ggttggaggt cttggaggct ggcttattgg tgcagcagca
     6721 ggaaaaatag cttactgtat tggatatggt gctcttaata gaggttgtga tattagcggg
     6781 aacccttatc cttgggatgg atttatatct gcgacagtaa gatgaataat gtagataaga
     6841 ttcgaaaaat acatattatc gtatgttggg tgtatatatt tttatcattc agggcgatta
     6901 taaatgacac ggagtatttt ttgcttattt ttttagcttt tatctactca atagtatcac
     6961 tacctctata ttctgtgaaa aataaaatag tatctatctg tctagccata aattcgattc
     7021 tgttaatgag tttccccatt ttaatcaata agtttttccc agaaagtttt ttgacttata
     7081 ccgtattaat aagtgttttt attacagagt tgataatttt tcatttaatt gggaaagatt
     7141 ttgatattaa attgactaac gaatataaga aaattagtca gtttagaagc aaggtgtctc
     7201 aatctccttg gataaaatat ttagagattt ctagttttat attaactata tttccatcta
     7261 ttctttatgg tacagttgat aatcatgtac tgactcttat ctttttgata aaaatttgtg
     7321 cagataccac gataaaattt ttattcatca gattatttga cacaagtact ttaatgaaga
     7381 ggagaatatt ttttcttttc gcattggatg ttatagctta cttattgtta ggatatcttt
     7441 tagtgattca aaaagcaggc tatttgtttt cggttttact tcttttttct aatttttcag
     7501 ttccatttat caaagaaaag gaattcgaat tatttaaaaa tagcaagtaa tagaaacata
     7561 ggttaaatct tagaacggct taaaatcaga tatgataaag ggaaatagtc ttatctaggt
     7621 aactaagtgc tacaaacaca atcgaggatc acttgttagg attacatttt aatcatgctt
     7681 aataagaatg gagaattcct atggggattg tattactctg aactttcgaa taccttagtt
     7741 ctcgtgattt tgagctattc tagctttaga atccttcaga atgtaaaatt ttaagcagtc
     7801 aaagacttag aatagcctga aaacatttat tttatagcaa ttctaaactt agaattgctc
     7861 atatatatgt atttgagctg ctcgatagtt aggacagctc tattctgaga aatctgagct
     7921 atcaatgctt cagaatagta tttcgccaat ggtttttatt gaagaggtga ttgtgttatg
     7981 atagtctaaa ataaaattga tttaatagag taaatggaga atcgttacat gaaacatttt
     8041 tttgcaggaa ttggtgagat aaaacttgtt ggctacttat tgtatatatg tgtaggacta
     8101 gcccctcttt ttcatatata tgtcataggt tcggaactga gttttgtgaa aatagtgtta
     8161 tctattttgg gagttatatt tgtaagtatg ttaactattg ctcgaattta tcggactttt
     8221 ctataaagaa tagtttggac ttgaactgta tctaaaaaca gaggttggta gattatcagc
     8281 ctctttcttg tcgttgaaaa gagtgagata tattgacttt tgaaaaaaag atgtcataat
     8341 tgagttggga taaacctaaa agtaatatag tagattgaat ctggaatagt ccgttatgac
     8401 tgttaaaata tttctagaaa ttaatttgac tttcctaatc gatttgttca catcttgttt
     8461 caatctacta tactttctcg ttaaaccgtt cggcaattca tggtgacatg gacacatagt
     8521 agtaagcaca ctatgtggct tggcagagct aaaaactgtt cccttgcgat aagcctaata
     8581 agcacaacat agggagttag agaagccgac tctaatcaac cactttgggc aatagtgaga
     8641 actgccctgt gcttttttat tttgaaaaaa tatggagttt gtcgttgaaa ttacttgatt
     8701 gtattttgga ctatcaagaa agattcaatg gaaaaacatg tcaagtatca acgaattata
     8761 agtatttaga gattttcaaa gtgaattttt gcttgactga tttacatcat ttatttggct
     8821 tacacaaaat cacacgagat tatgctagtc aaacaaaacc tgctattcaa gctggtgttt
     8881 ttattttaga agattttaga aatatcctat tgtacaatga tgtaatcgaa aggatatctt
     8941 tatgtgagtt tatcggcgat attttctatt ctaaaataac aagttgttgc atcgtagcta
     9001 aggatttatc taaaaatact atgaaattgg acgtcatatt ttttgaggat agaaataaaa
     9061 gatccgcagt tttaggttta cgaagagaca aaagcggagt atttaaacca gttactctac
     9121 attttacaag cgctaagaaa tatgctaaag ttcgtaaaac agatgtgaaa gaaatgaaat
     9181 ggctataaag attgtccgca ggcttaagct tgcgtttttt gttgtttaac gaaattaaaa
     9241 aacaagctct ctcatcggaa atgtttttat aggaatgaag gaagatgatg ctatgtttaa
     9301 aaagagaatc gaaaagggca aaagtagtgt ctttatcttt ttggagtaga agcttatgat
     9361 atagaaattt gtaataaaaa tgtaatataa aacatttgac aaatatttac ggggggagta
     9421 tacttaatat aagtatagtc taaaaatgac tatcagaaaa gaggtaaatt tagatgaata
     9481 agaaaaaaat gattttaaca agtctagcca gcgtcgctat cttaggggct ggttttgtta
     9541 cgtctcaacc tacttttgta agagcagaag aagctccaca agctgttgag aaatcttcat
     9601 cagagaagaa atatgatgaa gcaaaagcaa aatctgacgc tgctaagaag aattacgacg
     9661 aagctaaaaa gaaagcagca gaagctcaga aaaagtatga agatgatcag aagagaactg
     9721 aggcaaaagc ggaaaaagaa agaaaagctt ctgaaaagat agctgaggca acaaaagaag
     9781 ttcaacaagc gtacctagct tatctacaag ctagcaacga aagtcagaga aaagaggcag
     9841 ataagaagat aaaagaagct acgcaacgca aagatgaggc ggaagctgca tttgctacta
     9901 ttcgaacaac aattgtagtt cctgaaccaa gtgagttagc tgagactaag aaaaaagcag
     9961 aagaagctaa agcagaagaa aaagtagcta agagaaaata tgattatgca actctaaagc
    10021 tagcactagc gaagaaagaa gtagaggcta aggaacttga aattgaaaaa cttcaatatg
    10081 aaatttctac tttggaacaa gaagttgcta ctgctcaaca tcaagtagat aatttgaaaa
    10141 aacttcttgc tggtgcggat cctgatgatg gcacagaagt tatagaagct aaattaaaaa
    10201 aaggagaagc tgagctaaa
//
LOCUS       DAVEHY010000056        10038 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVEHY010000056 DAVEHY010000000
VERSION     DAVEHY010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.056"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(22..225)
                     /locus_tag="VUZ44_002021"
     CDS             complement(22..225)
                     /locus_tag="VUZ44_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320878.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(218..1300)
                     /locus_tag="VUZ44_002022"
     CDS             complement(218..1300)
                     /locus_tag="VUZ44_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU0320879.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1426..2208)
                     /locus_tag="VUZ44_002023"
     CDS             complement(1426..2208)
                     /locus_tag="VUZ44_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU0320880.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2208..3551)
                     /locus_tag="VUZ44_002024"
     CDS             complement(2208..3551)
                     /locus_tag="VUZ44_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU0320881.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILEAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3650..4966)
                     /locus_tag="VUZ44_002025"
     CDS             complement(3650..4966)
                     /locus_tag="VUZ44_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU0320882.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5159..6385
                     /locus_tag="VUZ44_002026"
     CDS             5159..6385
                     /locus_tag="VUZ44_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU0320883.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6584..8158
                     /locus_tag="VUZ44_002027"
     CDS             6584..8158
                     /locus_tag="VUZ44_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU0320884.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8422..9210
                     /gene="codY"
                     /locus_tag="VUZ44_002028"
     CDS             8422..9210
                     /gene="codY"
                     /locus_tag="VUZ44_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU0320885.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9210..9785
                     /locus_tag="VUZ44_002029"
     CDS             9210..9785
                     /locus_tag="VUZ44_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU0320886.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELFE"
     gene            9867..9952
                     /locus_tag="VUZ44_002030"
     tRNA            9867..9952
                     /locus_tag="VUZ44_002030"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9901..9903,aa:Leu,seq:aag)
BASE COUNT         2892 a         1900 c         2246 g         3000 t
ORIGIN      
        1 catcttttga tagatgactt cttaatcaat tatcatttcc attgttgttt cttggggttt
       61 catcccttgt ctttgataaa agcggagagc accctcgtta tcattccaga cacttagggt
      121 tagattattg cagccaattt ctttagcata atagcagaaa aatgacaata aaatagcccc
      181 tagatatttt gaaaggaaag cataggggct atatagttta atcaaaataa agcaaatctt
      241 tgctggtgct tgtaaagagg tcgaagccat ccttggtaac aacaccgcag tcttcaatac
      301 gaacaccgac tttaccaggg atatagatac ctggttcaac agagaagcac atgccttctt
      361 cgatgaccat gtcgtttcct tccatgatag atgggaattc atggacatcc ataccgatac
      421 catgcccgag acggtggttg aagtactcac cataaccagc tttttcgatg acctcacggg
      481 cagcgcggtc cacttcatga gcagtcacac ctggcttgat aaagtcaaga gcagcttgtt
      541 gggcttcaag agtcaagttg taaatatctt tcttgaattg gtctggtttg ccgacagcga
      601 ctgtacgagt catatctgac gcatagccat tgaccagaac acccaggtca aagaggagaa
      661 gagcatcatt ttcaacctta ttagctgctg gaatgccgtg tggattcgca gcattatcac
      721 cagtcaagac catggtatca aagctcattt cgtaaccttc acgtttcatg gcaaagtcaa
      781 tttgtgcgat gatatctgtc tcagtcttat caagagaaat attgtcaaaa ccaacatgaa
      841 cagccttgtc agcataaaga cctgcaacca tcattttttg cacttcatca gctgatttga
      901 tgaggcgcat gcgttggata cgaggagtga ggttgtcaaa ctcagcagtc tcaaaaactg
      961 ttttcaaacc atggtatttg gtcaagatga gattgtcaaa ctcaacagcg acacgtttga
     1021 agtcaagttg tggaagagca tgtttgattt tttgccatgg attttcagaa tcgacatagc
     1081 ccactactgg gaaggaaacg gtgctacttg cacgttctac ttcaagagct gggacaaaga
     1141 ggagaggttc ctgatctgct aggacaaaga ggaacatttg gcgttcatgg ggatcactgt
     1201 aaaaaccagt gaggtaattg attgtgacgg ggtcagatac gacagcgacg tctagttttt
     1261 ctgattcaag atatgttagg atttgttgta atttagacat atgctacctt ctttctatcc
     1321 ctctattttg gcaaaaaatg agagaaaatg caagggagaa gggtaaaaga aaagacaaaa
     1381 aactccgaca agataacgga gttctttgat atcattttcc tttgtttaag aaaagtcagc
     1441 cttgcttttg acgtcactgt actcttcagc gatttcttgg ctgaggatat cctcataggc
     1501 agggagttgg atatcctgac catatttctt cttgagggca gtagtaacta ggcgataagc
     1561 cagattggca ttacgagaga ggataggccc gtggaagtag gaaccaaaga cattcttata
     1621 atgaacccct tcaccgacct tttcttcgtt gtttccattt ccatagacaa cctgtcccag
     1681 cggtttttgg tcatcagaga ggaaggtacg gccttggtga ttttcaaatc catagtaggt
     1741 ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata aaacggttat tggtctggtt
     1801 gagcgtgtag tgtcccatga cccctagccc ttcgatacgt tttcctgaag cttcaacata
     1861 atattgaccc aatagttgga aaccaccgca gatagccaga actacaccgt cgttttggat
     1921 gtagttgtca atgctctctt ttttagcagg taggtcgtct gcaatgatac tttgttcaaa
     1981 gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt tcatcaaagt catcatggag
     2041 agaaacgatg tcaacggtca catgggctcc cagtttttca gccacatact tgagcatgag
     2101 gatgtttcca ttgtccccgt aggtattcat gagatttccg tagaggtggg caatgttgag
     2161 ctgatagggg taattgccat cttttgagga aagtgaagta taaaccatta gttcatctcc
     2221 tttctaacaa tctgacgact agccagcagt tcacgaaatt ccagcatggc agtataagtt
     2281 gccagaatat aggcatgctt gcagtcttga ttctcaatgg tcttgagaac ttgctccaga
     2341 ttactcgttt cagtgatttt ctcagctgga tagccagtca ctcggaggcg acgagcgatt
     2401 tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt ccatgtcagt gatttgttca
     2461 aagtctgcat cccagatcca gctagtgtca attccatctg catagttggc attaaggagg
     2521 acagataggc taaatggata aggtgctagt ttgatcattt cgatagcttg ggttgcaccg
     2581 actggatttt taatcaagac aagggtacat tccttgtcac cgatatgaaa ggtttcttgg
     2641 cgtccaaaga cagcacggct cttgtcaaat ccctgtttga tgagttgcga atcggcacct
     2701 aggaaacggg cgatggccac agcagctagg gcgttataga tattatagag cccgccgatt
     2761 tggataccgt attcttggcc gtctatgaca aagcgagagc gattgttggt caactcaacc
     2821 agttttgtca aacgatagtc gagatcagga cgtttgcatc cacaaccttc acagatatag
     2881 gcacccaagt ttgcataggt attatgctca tatttgagga tgccttggca gtcaggacag
     2941 agaatccctt cggtattgta gtgagccagt tgggctggtc ctttttccaa gtcaaaacca
     3001 aaatactcta tagggtttgg aatagttggc ttgtagaaaa gtggactgtc tccgttaagg
     3061 agaacagtag cagttggaac tttccgaatg gcttccaata tcatgttata ggtagtatag
     3121 atttcaccga aacggtccat ctggtcacgg aagatattag taatgacaaa aagactaggc
     3181 tggatatagt cacagatacg agatagactg gcttcgtcaa tttcgaggac ggcaatattt
     3241 ttcccagttt ttgaagattt ggctgttagg aaggttgttg caatccctgt aatcatgttg
     3301 gcaccgcttg ggttggttag aacttgacca taaacctctt ttaaaatgcc gacagtgagg
     3361 gcagttgtca gggtttttcc atttgttcca gtgacaacga caatctcgta gttcttagct
     3421 aggttttgta aaatatcttt atcaaattga agggcgactt tacctgggag cgtacttcca
     3481 cgtccaagac ggcttaaaac gaagtgggaa gaacgcccag caagaaggcc caaagtagtt
     3541 tttaagttca tgtttctatt atatcacaaa agagggaaaa gacagatttg gtgtttcgta
     3601 gaagtaaaaa cagcccaaag agggctgtca gttaagatga gatttcaact taaatcgcaa
     3661 acaagtcatt caagttctca gccaaggttg ggtgagtgaa gatttgtttt gtgaagtaag
     3721 tgtaaggaat cttgttgtcc atagcaacag taatgatgtt gatgatttct tgagaacctt
     3781 ctgagaagat gcttgctcca agaatttctt ttgtttcagt attgacaaca gctttgaagg
     3841 caccgcgaag gtctccattt acgtgaccac gaggcattgc tgcaacgggg atttccttaa
     3901 cagcgtatgg aagtttcaaa tcagctgctt ggctttcagt caaaccaact tgtgaaagtg
     3961 caggtgtgat gaacatagta tttggcacat tgagacggtc ttcaagtgtg tagctgccat
     4021 ctccagcaag gtagctgtaa acaacacgga agtcatcaag tgaaatgtaa gtaaattgaa
     4081 ggccaccgtt gacatctcca actgcaaaga caccaggaac gtttgtttga cagtgtttgt
     4141 ctactttaat agcaccacgt tcagttagtt caatatctgt attttcaagt tgaagtggtt
     4201 ctacatttgg tttgcgtcca gttgcgtaga gaagggcgtc gaaacggtaa gtttcgtctt
     4261 cagttacgac aagcacttgg tcaccatcgt ttttgatttc agtagtatgg atattttgaa
     4321 gcaattcaat gccatcttct tccatgtatt gtttagcaag agctgcgatg gaaggttctg
     4381 cacgaggtag gaatgtatcc aaggcatcta ggactgtgac cttgcttcca agtttgttgt
     4441 aaaggccggc aaattcaaga ccgatatttc cgccaccaag gattccaagt ttttcaggta
     4501 atttgtccaa gctttggata cctgttgagt caaagatgtt tttgcttgta gcaagtccag
     4561 ggattggcaa gacgtttgaa acagcaccag tgttgatgac gattgtttca gcagtcagtt
     4621 ctttcttttc atcaccagct tggatttcga tgactttatt tgaaaggaag tgagcttccg
     4681 catcaaagat atctacgcct gtaccagcaa cagtcgcata gtttttaccg ttgaggcgac
     4741 cagtgatcgt gtttttagta gcaatgactt cttcaaaaga caagtccttt tcagcagcaa
     4801 ctagcaaggt tttagttggg atacaaccaa tgttgataca agttccaccg tacatagcct
     4861 tgctgcgttc aacgagggca acttttttgc cagctgaagc caatttacct gctagtgttt
     4921 taccagcttt accaaatcca ataacaatta aatcgtatgt taacatttat cttcctccta
     4981 ttcgaatttc attctagcac aagaaaaaaa cttttgcaca attctgctac ggaaaagaca
     5041 gaaaaagata aaaacgcttt ccagacaaaa aactagtaat tttttgacaa gcttgataaa
     5101 ctaaaatcct atctattttt atataagata gaataaatgt tcgaaaatag gaggttttat
     5161 gaaatcgaat cgttatatta ttgcctttgc tggggtcatt ttacacttaa tgctgggttc
     5221 gacttatgct tggagtgttt atcgtaaccc tattattgaa aaaacgggat gggatcaggc
     5281 ttctgttgcc ttcgccttta gtctagcaat cttttgtttg ggcttatcgg ctgcatttat
     5341 ggggcgtttg gtagaaaaat ttggtccgaa agtcatggga agtctatctg cttttctata
     5401 cgcaggtgga aatatcttaa caggatttgc aatagaccgt caggagctgt ggttgttgta
     5461 tctcgcttat ggcattttag gtgggcttgg tttgggagca ggctatatta cccctgtgtc
     5521 gacgattata aaatggtttc ctgataaacg tggtctcgca acaggtttag cgattatggg
     5581 gtttggtttt gcttctttat tgactagtcc catagcgcaa cacctcatcg caggggtagg
     5641 gcttgtagaa actttttata ttttaggagc aagttacttt attatcatgc tcctagcttc
     5701 acaattcatt aagcgtccaa atgagcaaga gcttgcaatt ttatcttctt cagggaaaga
     5761 aaaaacagcc tctttgacgc aaggaatggc tgcaaatcag gctctaaaaa gcaatcggtt
     5821 ttatatgctt tggattattt tctttatcaa catagcttgt ggtttaggct taatttcagc
     5881 ggcatcgcca atggcacagg agatggctgg cttgtctaca agtcatgcag cagtaatggt
     5941 gggtgttttg gggattttca atggatttgg tcgcttgctc tgggcgagtt tgtctgacta
     6001 tatcggtcgc cctctaacct ttagtatatt actgcttgtc aatcttttct tttctctctc
     6061 actttggctc tttacagatt ccgttttatt tgtagttgct atgtctattt tgatgacttg
     6121 ctatggagct ggtttttctt tgattccagc ttatctcagt gatatttttg gaaccaagga
     6181 attggccgct ctgcatggtt atattttaac agcttgggca atggctggtt tagcgggacc
     6241 tattttatta gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt
     6301 tctcatttta tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa
     6361 agaaagtcaa aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt
     6421 cttgtgttat actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc
     6481 aacacgattt tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag
     6541 ccctataggg tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt
     6601 aaacttgtct gctgatttgc tagcagaaat tgaaaaagct ggttttgtag aagctagtcc
     6661 tatccaagaa caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca
     6721 gactggtaca ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga
     6781 agaagcgact atccaagcct tggtcatcgc tccaactcgt gaactagctg tccaaagtca
     6841 agaagaactc ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg
     6901 atcaagcatt gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac
     6961 tccaggtcgc ctcttggact tgattaaacg caaggccttg aaattacaag acattgaaac
     7021 ccttatcctt gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc
     7081 cattatttcc cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga
     7141 tgccatcaaa cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc
     7201 taaggaattg acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa
     7261 atttgacacc atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg
     7321 tcgtaccaaa cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc
     7381 agaaggaatt catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa
     7441 aaatggcaat cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc
     7501 aggtgtgacc catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg
     7561 tatcggtcgt acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa
     7621 cgaaatgggt taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa
     7681 acctgcaagt gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga
     7741 acgtgatttt gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg
     7801 caaattggct gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt
     7861 ccaagaccca gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa
     7921 accatcaggt aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga
     7981 cgaccgtcga gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag
     8041 tcgtggcaac gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg
     8101 caatacttta agcgaaaagc aaacaggctt tgttattcgt aacaagggcg ataaataaga
     8161 aaaagcggtt caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat
     8221 aaaattatta tattatcttt tataatgtta tgatacaaaa aaataggcaa cttgtcaata
     8281 gaaaaggaac aatttaatta aaaatattct ggtttttaat taaattgtaa gtcaatgcaa
     8341 gtcaataagg aattttcaga taattattga aaaagagacg tttttatgtt ataatgatag
     8401 cgattaaatt cgaggtgaaa aatggcacat ttattagaaa aaactagaaa aattacatca
     8461 attttgaaac gctcagagga gcagttgcag gatgagcttc cttacaacgc tattacgcgt
     8521 cagttagcgg atattattca ttgcaatgcc tgcattatca atagtaaggg acgtctgctt
     8581 ggctatttta tgcgttataa aacaaataca gatcgcgtag agcaattctt ccaaactaag
     8641 attttcccag atgactacgt tcaaggggct aatatgattt acgaaacaga agcaaacttg
     8701 cctgttgagc atgatatgag tattttccct gttgagagta gagatgattt tccagatggc
     8761 ttgacgacta ttgcaccgat tcatgtatcg gggattcgcc ttggttcttt gattatttgg
     8821 cgtaatgata aaaaattcga agatgaggac ttggttcttg ttgagattgc cagtaccgtt
     8881 gttgggattc agcttcttaa cttccaacgt gaagaagatg agaaaaatat tcgtcgtcgt
     8941 actgctgtca ccatggcggt caataccctt tcttactccg aactccgtgc tgtttcagca
     9001 attttagggg aattaaatgg aaatgaaggg aagttgactg cgtcagtgat tgcagatcgt
     9061 atcggaatca ctcgctctgt gattgtcaat gctcttcgta aacttgagtc tgcggggatt
     9121 attgaaagtc gctcacttgg aatgaaggga acctatctta aggtcttgat ttcagatatt
     9181 tttgaagaag tgaagaaaag agattactaa tgacaaaggc tttaatttcg attgattata
     9241 cagaagattt tgttgctgat agtgggaaac taacagcagg tgctccagct caggcgattt
     9301 cggatgccat cagcaaggta actcgattag cttttgaacg aggagattat atcttcttta
     9361 ctattgatgc tcatgaagaa aacgattgtt tccatccgga aagtaagtta tttcctcctc
     9421 ataatctgat tgggacgagt ggacggaatt tatatggaga tttggggatc ttttatcaag
     9481 agcatggttc agacagtcgt gtcttttgga tggataaacg ccattactca gctttttcag
     9541 ggactgacct agatattcgt ttgagagagc gtagagtgtc taccgttatc ttaacaggtg
     9601 tcttgacgga tatctgtgtc ctacatacag ctatagatgc ctataatcta ggatatgaca
     9661 tcgagattgt taaaccagct gttgcttcca tctggcctga aaatcatcaa tttgccctag
     9721 gtcatttcaa aaatacactc ggagctaagt tagtagatga aaatctaaat gaactttttg
     9781 agtaacctgg ttggtgaaaa tgaaaaaatt tgaaaaaaag tgttgacaag catcccaaaa
     9841 gttgatatac tagtaaagta atcgacgcgg ggatggcgga attggcagac gcgcaggact
     9901 aaggatcctg tgaccgcttt aggtcgtgag ggttcaagtc cctctctccg cataggaaaa
     9961 gagctagcta aagctagctc ttttgtattt ctctaaaaaa ttagaatcca gtcaaatgta
    10021 gtggagaatc agcgaaaa
//
LOCUS       DAVEHY010000057         9403 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVEHY010000057 DAVEHY010000000
VERSION     DAVEHY010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.057"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            1..195
                     /locus_tag="VUZ44_002031"
                     /pseudo
     CDS             1..195
                     /locus_tag="VUZ44_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(329..1297)
                     /locus_tag="VUZ44_002032"
     CDS             complement(329..1297)
                     /locus_tag="VUZ44_002032"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU0320887.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALSEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1442..1984)
                     /locus_tag="VUZ44_002033"
     CDS             complement(1442..1984)
                     /locus_tag="VUZ44_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU0320888.1"
                     /translation="MDQLLGVLFPDSTFLNAFESAIVAPLVEEPLKLLPLVFVLALIP
                     VRKLKSLFLLGIASGLGFQMIEDIGYIRTDLPEGFDFTISRILERIISGIASHWTFSG
                     LAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAIPVVTAI
                     ALYGFYHAYCFVEKHNELMT"
     gene            complement(1988..2287)
                     /locus_tag="VUZ44_002034"
     CDS             complement(1988..2287)
                     /locus_tag="VUZ44_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320889.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFHIGKKWELPKKVLILSLLGAICSFTSLLLFGIYNHRRKSSKV"
     gene            complement(2312..2809)
                     /locus_tag="VUZ44_002035"
     CDS             complement(2312..2809)
                     /locus_tag="VUZ44_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU0320890.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     AVVEL"
     gene            complement(2882..4243)
                     /gene="radA"
                     /locus_tag="VUZ44_002036"
     CDS             complement(2882..4243)
                     /gene="radA"
                     /locus_tag="VUZ44_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU0320891.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4257..4772)
                     /locus_tag="VUZ44_002037"
     CDS             complement(4257..4772)
                     /locus_tag="VUZ44_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU0320892.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGEMLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4774..5217)
                     /locus_tag="VUZ44_002038"
     CDS             complement(4774..5217)
                     /locus_tag="VUZ44_002038"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU0320893.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            complement(5277..5370)
                     /gene="ffs"
                     /locus_tag="VUZ44_002039"
     ncRNA           complement(5277..5370)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VUZ44_002039"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5403..5870)
                     /locus_tag="VUZ44_002040"
     CDS             complement(5403..5870)
                     /locus_tag="VUZ44_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU0320894.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(6071..7357)
                     /locus_tag="VUZ44_002041"
     CDS             complement(6071..7357)
                     /locus_tag="VUZ44_002041"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU0320895.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7588..7824)
                     /locus_tag="VUZ44_002042"
     CDS             complement(7588..7824)
                     /locus_tag="VUZ44_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU0320896.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            8090..8886
                     /locus_tag="VUZ44_002043"
                     /pseudo
     CDS             8090..8886
                     /locus_tag="VUZ44_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8921..9403)
                     /locus_tag="VUZ44_002044"
                     /pseudo
     CDS             complement(8921..9403)
                     /locus_tag="VUZ44_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3014 a         2236 c         1509 g         2644 t
ORIGIN      
        1 aaggaaatca tcgccaaact ggactacgac gccccatctt gccctgagtg cggaaaccaa
       61 ttgaagaaat atgactttca aaaaccttct aaaattcctt atcttgaaac gactggtata
      121 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
      181 gtcgctgaaa cttctgatga cgtacagtca tatttcttct ctttttatta tatcacagtt
      241 ttaaatctag ctttactaga ttcaccgcta ctatctattt attcggaaaa aagacgaaaa
      301 aacctgagaa tcatctcagg cttggtcatt aaattttttt ctcaatatcg aaaagtggag
      361 aaagtggtcg tttttcatga atacgtacga tagcatcccc taggagatga gcgattgaaa
      421 tctgctcaat cttatcaatc aaacgctctt ctggcagata gatggtatcc aaaacaacca
      481 atttcttaat agctgatttt tggatattgt ccgtagcagg accagaaaga actgggtgcg
      541 tacagcttgc atagacttca acagcaccag cttccgaaag agcatctgcc gcatgacaaa
      601 tcgttccagc ggtatcaatc atatcatcaa tcaagataca agtcttgcct tcaaccttac
      661 cgatgatgtt cataacttca ctagtattca tcttatcaac gctacgacgt ttatcaataa
      721 tagcgataga tgttttcaaa aattctgcca acttacgagc acgagtcacc cctccatggt
      781 ccgggctgac aaccacatag tcagaaccaa ccataccacg acgctcaaaa taatctgcaa
      841 tcagaggagc acccatcaaa tgatccacag gaatatcaaa gaatccttga atttgcgcag
      901 catgcaagtc gatggtcaat aaacgatcca ctccagctac ttcaagcata tttgcgacaa
      961 gttttgaagt gattggctca cgcgctctcg cctttctatc ctgacgtgca tacccatagt
     1021 aaggcatgac aacattgaca gattctgcac tcgcacgctt caaagcatct accataatca
     1081 aaatttcaag cagattgtca tttacaggcg aactagttga ttgtaggata aagacgtgtt
     1141 tcccacggat tgattcttca atgttgacct gaatctctcc atctgaaaat tggcgaacac
     1201 ttgatttccc caactctatc ccaatctcct gcgctacacg ttctgccaat tctttattag
     1261 aagaaagggc aaacagcttt aaatcagaaa aagacatgat ttcctccggt atatatgtat
     1321 aacttgtgct tttcacaaga ttttccatct accattgtag cgctttttgc actatttttc
     1381 aatcaaaaat aaaagaaggg caccatattt gtacccttgc atcattcttt tgaaaaatat
     1441 tctaggtcat caactcattg tgtttctcaa caaagcaata agcatgataa aaaccataga
     1501 gagcaatagc cgtaaccact ggaatcgcta aaggcaactc tgtttccaac tccacaaaag
     1561 gagagttaaa caagaagtga gttcccaagg ctaaacctag aaaaataagg ccctgtttct
     1621 tgccaacctt ctgtccttta taggctctgt aaagcaagta aacacctact acagctagac
     1681 ctgaaaaagt ccagtgagag gcaattcctg agatgatacg ctctaaaatt cgcgaaatag
     1741 taaagtcaaa gccctctggc aaatccgtac gaatataacc aatatcctca atcatttgga
     1801 atcccaaacc ggaagcaatt ccaagtaaaa acaaagattt taattttcgc acaggaatca
     1861 aagccaaaac aaaaacaagt ggcaataatt tcaagggttc ttctaccaaa ggagccacaa
     1921 tagcactttc aaaggcattt aaaaatgtac tatctgggaa aagaaccccc agtaactggt
     1981 cgatttttta taccttagat gactttcgtc tgtgattata gattccaaat agtaagagag
     2041 aagtaaagga acagattgct cccaataaag acagaatcaa aaccttcttt ggcaattccc
     2101 attttttccc aatatggaag agaaaataaa gagccggaat catgtaaaag agagctagaa
     2161 agatagaaac tcccattagt ccatattccg cacctgacct cgaaccgtcc gtatagtaga
     2221 tggtttcata ctgtaaacca atacatagca ataaaataaa aataaataaa atactgcttt
     2281 tcttcataca ctttctttct aaatgaagta tttataattc tacgactgcc atacttcctg
     2341 tatcaacatt gtaaatggca ccagagataa tgacatcgtc tggtattagg ggagactcga
     2401 taagcagttg catatcctcg cgtacactct cttctatatc ttggaagggc aagaagtcct
     2461 ggtctgacac atctacacct aattcctctt ttaaatactc ctgaaaaggt tcattttcaa
     2521 aggtctgagc accacagtct gtatggtgca ataccacaat ctctcttgtc cccatttgtt
     2581 gctgggaaat aactagcgaa cgaatcatgt cttcagtcac tcgaccacct gcattccgca
     2641 agatatgagc atccccaagt gccaagccca gagcttgcgc aacgtgcaga cgagagtcca
     2701 tacaggtcac aatagctact cttgttttgg gtttaagtgg cagatttaac tgcccatgta
     2761 gggcaacata agcctgatta gcttgcataa actgttcaaa atacgacacg attccctcct
     2821 tgaaaatttg atagtcaaat atttctccta tcttatcatt tttaagagaa tttgtcacgg
     2881 attatgcaaa gacctttttc aaaacttcct gaatcgttgt cacgccaatg acctgaattt
     2941 ccttaggcag agtgattcct gtcaaggaat tcttaggtac ataaatctta gtaaagccca
     3001 gtttagcagc ttcgttgatg cgttgctcaa tacgattcac gcgccgaatc tctcctgtca
     3061 agcccagttc tccgacaaaa cattcctgag gattagttgg cttgtctttg tagctcgaag
     3121 caatagcaac tgcaacagcc aagtcaatcg caggttcatc caatttaaca ccaccagcag
     3181 atttgagata ggcatcctga ttttgcaaga gaagccctgc ccgtttttcc aaaacagcca
     3241 taatcaagct agcacggtta aaatcaagtc ctgtcgtagt acgcttggca tttccaaaca
     3301 tggtcggtgt taccaaagcc tgaacctccg ccaaaatcgg acgcgtccct tccatggtta
     3361 caacgatgga ggaaccagtc gccccatcca aacgctcttc taggaaaact tgactcggat
     3421 tgagtacctc aaccaagccg cccgactgca tctcaaaaat cccaatctca ttagtggaac
     3481 caaaacgatt tttgaccgct ctcaaaatac gaaaggtgtg gtgacgctcc ccttcaaagt
     3541 aaagcaccgt atccaccata tgctccaaca tacgaggccc agccaaggtt ccttctttgg
     3601 tcacatgacc tacgataaag atggcaatgt tattggtctt ggccaactgc atgagttcag
     3661 cggtcacttc acgcacctga gaaacagacc cctgcacccc tgaaatctca ggagacatga
     3721 tggtctggat ggaatcaata atgagaaagt ctggctggat acgctccact tctgcacgaa
     3781 cactctgcat attggtctct gcatagagat aaaactcact atcaatatca cctaagcgct
     3841 ctgcacgtag tttaatctgc tgggcagact cctccccact gacatagaga actgtcccca
     3901 cttgggacaa ctgggttgag acttgtagga gaagagttga tttcccaatc ccaggatccc
     3961 caccgatgag gacgagactt cctggtacca ctccgcctcc aagcacacgg ttgaattcct
     4021 ccatctccgt cttagttcga ttgacattga tggaagtcac ctcagctagt ttcatgggct
     4081 tggttttctc acctgtcaag gacacacgcg cattcttgac ctcggcaacc tcaacctctt
     4141 ccacaaaaga agaccaagac ccacagttgg ggcaacgtcc cagatattta ggagaattat
     4201 acccacaatt ttgacataca aatgtcgctt ttttctttgc gatgacaaac ctctttctat
     4261 atctctaact cacactcaat cacttggcaa aaatcaatct tctcatttgg cacaaactgg
     4321 cgcatgagca ttcgatgagc aacaactacc acagtctgat gttctcgata cttagacata
     4381 cattctagaa accgagactt catttccgta gctgtctcat attgaatagg actattagga
     4441 agcatctccc ccttgttttc taaaaacagt cttctagctg tttcaaagtt ttctattcct
     4501 gttttataga cctgccattc atgtaataaa ggctctactc ttaaaggaag acccgtagca
     4561 cagaccacat acgaagccgt ttctaaagct cttgtgactg cagaagatac gattatttca
     4621 gctgacgaga gtaaaggatt tttgctcaat ttctggactt gctgccgtcc catctcagac
     4681 aagggtgcca aatctatccc aaatcctata taagaacgct cctctaactc acggtaatct
     4741 ggctccccat gacgtacaaa gataatcttc attctagtgc cctgtcgatc caaatccacc
     4801 agttcgaacg ccaccagctg catctccatc tgcaattaag aaagtagcaa aaacagcctg
     4861 gacaatacgc tccccaactt caagaacaac ctcttggtct gtgatattct tcatctgcgc
     4921 aaaaatatgc ccttcatttc caggatttcc ataataatcc ccatcaatga ccccaactga
     4981 gttaattaaa accaagccct tcttacgagg atttgaagaa cgatcataga ggtagagaac
     5041 ctcagtcggc tgcatataag ccttaacccc tgtcggaacc aagacaatct ctcctggcgc
     5101 aacaactgta cgcacagcaa cctttaagtc gtaaccagcc gcatgcgctg tctcacgctt
     5161 gggcaataaa ttttcatctg taaaactcga aaccaattca aaaccacgaa ttttcataat
     5221 tttctctttt ctattatcat ttattctaga ttattctatc ttatttattc ggaaaaagca
     5281 cgaaaaaaga gcacacaatt caaatcgctt agggctgctg gattcctccc ctgacccgct
     5341 tcacgcagaa ctgttgctcc actatttatt atatcacatt cctattcatt ttaaaagcaa
     5401 aattattttt tccgtctatt tctaaaaaaa tcctgcatga tagctgcgca ttcatcttcc
     5461 aaaattccta tttcaacctc cacacgatgg ttaagacgct catctgtcaa gatatcgtac
     5521 aaactcccag cagcgccaaa tttctggttt ttagccccat agaccacatt tggaatgcgg
     5581 gcaagcccaa tcgccccact acacatgaca caaggttcaa tggtcacaaa aagtgtgcaa
     5641 tccagcaagc gccagctctc ctcactcaag ttcgcatcct ctatagccat aatttccgca
     5701 tgcataaccg ctcgctgtaa ttcctcacgc gcattatgcc cacgaccaat gatttcccca
     5761 tctttgacaa tcacacaacc aattggaatt tcatcgtgtt caagagcaat ctcagcctct
     5821 ctcaaagcct ccctcataaa gacttctttt tcttcaagcg tataatacat ctcttttctc
     5881 ttttcctact tatcgatttt attattatat catgaatccc aacacaaaaa aagccaccga
     5941 atgcggtgac tctataggga gattattatg aaaaagaaaa gtttaggata tttgttacaa
     6001 caagttagga ggtcttcttg taaccgtcta tagtataccc gacctatctt aaacaaatct
     6061 taaaaatctc ttaggaccaa acactttcta aaatatttgt ttgttcacga ccaggaccta
     6121 ctgagaaagt agaaatacga acgccaacca attcactcac acgacgaaca tagttacgcg
     6181 cattctcagg aagatcttcc aaattgcgaa ctccggtaat atcttctgac caacctggca
     6241 actcttcata gataggcttg caacgtttca attgctcaag actagctgga tagtagtcaa
     6301 tacgttgacc atcaagatca taggccacac agattttcac agtatccaaa ccgctcaaaa
     6361 catcaataga gttcaaagaa aggttagtaa taccagaaac acgacggcta tgacgcatca
     6421 caactgagtc aaaccaacct acacgacgtg gacgaccagt tgttgtacca tactcatgac
     6481 ccacttcacg gatacgttct cccacttcat caaacaactc agttgggaaa ggaccatctc
     6541 ctacacgact cgtataagct ttacatacac ctacaacctt gtcaatcttg cttggaccga
     6601 caccagaacc aattgtcaca ccaccagcta cagggtttga tgacgtaaca aatggataag
     6661 taccttggtc gatatctagc ataacacctt gtgcaccttc aaaaagcaca cgtttgccat
     6721 tatcaagcgc atcattcaag ataacagatg tatctatcac gtatttcttg atttgttgac
     6781 catattcgta atattcttca aaaatatcat cgaaaacaat cgctttactg tcatacaatt
     6841 tttcaaaaag acgattcttt tcagcaaggt tacgttctaa acgctcacgg aaaatatctt
     6901 tatctaaaag atctgcaata cgaattccaa cacgagcagc cttgtccata taagctggac
     6961 caattccctt aattgtcgta ccaatcttat tgtcgccctt agcttcttct tgcaagcgat
     7021 ccaactcgat atgataaggc aaaataacat gcgcacgatc agaaatacgc aagttatcag
     7081 ttgttacacc ttcctcatga agatagctca actcttttac aagagattta ggatttacaa
     7141 ccataccatt cccaatgaca gatatttttt cagggaagaa aatcccagat ggaatcaagt
     7201 gcaacttaaa tttcttaccg tcaatcacaa tcgtgtgacc agcattatca ccaccttggt
     7261 aacgtgcaat cacttctgca ttcgctgaaa ggaagtctgt aatcttccct ttaccttcat
     7321 caccccattg ggtacctaca acaacaactg aagtcataat cttgtctgag ccctcaggct
     7381 cttcctttct cacatacatg gcaggactct cacctgcaat tatatcttac aatttattat
     7441 aataaaaaat cgccttttta tcaagaagaa acaatagaaa gatttgctat ttccaactat
     7501 taaaaaatga tttagaaaaa ttactagcta tttactatca tctttccata aaagagtaaa
     7561 ttagttcgga aatttactaa aattacctca acaagaaata aacccccgat tcattaccaa
     7621 tttttcaaga tacaaacgat aagcaacacg ataatggtaa acaataaaat ccttacgaca
     7681 accaatgcca tatctcacta aataataaat taaaaattta aaatgaacat gttcccagtc
     7741 aaaattatca ccaaatgtag gaccatactc ttcttcaata ctatcataga aattagccat
     7801 ctgctcataa attttttgta acataatcaa atactccttt tcttttttat aaacttattc
     7861 taacaaaaaa ttttacacat tcactatcaa ttcctgaatt gttaaaatac cagcctcaac
     7921 aagataaaaa taggaaaagt tgacaaaata gaaacaaatt tgctacctaa atttcaaaaa
     7981 attaaagttc taaaaagacc gccttaaaac ttttgggtaa gtcctattag aactataata
     8041 tttttatata ggtattatgg ttctgatttt ctagtataaa aaaattcaaa ctagaattct
     8101 tcttagaaaa ggccgtttta agtgctatca ttgctcaaaa atggagctcg ctgagacttc
     8161 tatcgtcaag aagaatcatc aaattccttg tatcatcaac caaaagattg ctcagaagct
     8221 aattgaaaag acttctatga ccgacattga tcatcagttg tctatttcaa cttcaactgt
     8281 cattcgcaag atcaataatt ttcactttga gcatgatttt tcgcgtcttc ctgagattat
     8341 gtcctaggac gttgaaacag tccggggagt gactgtttca atcggggatg gagatgagct
     8401 ttattgctca ggactttgat aaactcaata tcataactgt tcttgagagc agaacacaag
     8461 ccatcatccg aaatcccatg aatacaaggc tatcaagcgc tactggaagc tcattcaaca
     8521 agatagtcag aaactgagtg ataaacgatt ttatcgccct acttttcgta tgcacttgac
     8581 taataaagaa attctagata aacttttgag ctattccgaa gacttgaaac accactataa
     8641 tctctatcag ctcttgcttt tccacctctg tttcaaactt tgtttaaaac cttcctcaaa
     8701 gataaagaga aaatcgtcaa cgcccttcaa ttaccttatt ccaacgccaa actggaagcc
     8761 accaataatc tcatcaaact tatcaagcac aatgcctttg gttttaggaa ctttgaaaac
     8821 ttcaaaaaag aaaggacgaa atttgtcctt tctagatctt cgctttcttc aacccactac
     8881 agttgacaaa gaaccgaaaa atgtctcgcc tctaatatag tcaattgaaa caagaacaag
     8941 agaaaagagc ctcgtaaaag gtattgcaac ttggtaatac ctttttgagg ttctttttga
     9001 tataagccca tgttttctca ataggattgt actcaggtga gtagggagga agaggtaaaa
     9061 gtttatgccc aaactcctcg cataaaagtt ctaacttacc cattctatgg aatcttgcat
     9121 tatccataat aataaccgat ggtgtggtta atgttggtaa gagaaacttc tgaaaccaag
     9181 cttcaaaaaa gtcgctcgtc accatctctt cgtaagtcat tggagcgatt aactcaccat
     9241 ttgttagacc tgcaaccaaa gaaatcctct gatatcttct tccagatact ttacctctta
     9301 ttaactgacc ttttaatgag cgaccatatt ctcgataaaa ataagtatcg aatcctgttt
     9361 catcaatcta aacaggtgct aggtgcttta aactattaaa att
//
LOCUS       DAVEHY010000058         8681 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVEHY010000058 DAVEHY010000000
VERSION     DAVEHY010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8681
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.058"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(220..702)
                     /gene="greA"
                     /locus_tag="VUZ44_002045"
     CDS             complement(220..702)
                     /gene="greA"
                     /locus_tag="VUZ44_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU0320897.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(773..2428)
                     /gene="mltG"
                     /locus_tag="VUZ44_002046"
     CDS             complement(773..2428)
                     /gene="mltG"
                     /locus_tag="VUZ44_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU0320898.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2509..3003)
                     /locus_tag="VUZ44_002047"
     CDS             complement(2509..3003)
                     /locus_tag="VUZ44_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320899.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(3000..3464)
                     /locus_tag="VUZ44_002048"
     CDS             complement(3000..3464)
                     /locus_tag="VUZ44_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320900.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEEILLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3474..4808)
                     /locus_tag="VUZ44_002049"
     CDS             complement(3474..4808)
                     /locus_tag="VUZ44_002049"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU0320901.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4819..5436)
                     /locus_tag="VUZ44_002050"
     CDS             complement(4819..5436)
                     /locus_tag="VUZ44_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU0320902.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5484..8582)
                     /locus_tag="VUZ44_002051"
     CDS             complement(5484..8582)
                     /locus_tag="VUZ44_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU0320903.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFAVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
BASE COUNT         2380 a         1979 c         1655 g         2667 t
ORIGIN      
        1 actatacatc taatactcaa taaaaatcaa agagcaaact aggaaactag ccgcaggttg
       61 ctcaaaacac tgttttgagg ttgtagatga aactgacgaa gtcagtaacc atacatacgg
      121 caaggcgacg ctgacgtggt ttgaagagat tttcgaagag tagcaaaatg gaaaaaggag
      181 tgagtgaagc acatcgcctc cccactcctt tttctgtttt taggctgttt tttcaacctt
      241 caagattttt acatcatagc taccaacagg cgtttcaatg gttgctgtat cacctgtttt
      301 cttgccaatc aaggcctgcc caattgggct ttcatttgaa accttacctg caaaggcatc
      361 cgcaccagct gaacctacga taatataaac ttcttcttcg tcctcaccaa tttcttggat
      421 ggtgactgtt ttaccaatcg ctacttcgtc ctgggcaact gcgtcgctat tgacgatttc
      481 agcatagcgg atttttgttt ctaagctaga gatttgtcct tcgacaaagg cttgttcatc
      541 cttagctgct tcgtactcac tgttttctga aaggtcaccg tatgaacggg caatcttaat
      601 gcgttctacc acttctggtc gacgaaccaa tttcaattct tctaattctt tttcaagttt
      661 ttccttttcc tcaagggtca taggatatgt tttttctgcc atttttctca actttcttct
      721 gataatattt tctaaagaaa attatgtgaa gtatcacata attttagttt gtttagttta
      781 atttgctgtt gacatgttca gcgacattgc ggtcgtggtc ttcttgattg ttagcatagt
      841 agaccttgcc ttctgtgaca tctgctacaa agtagaggtt atcgctctta gtttgattga
      901 tgcttgactc aatcgcatcc agacttggac tatcgactgg accaggcatg agacctacat
      961 ttttataaac attataaggt gaatcaatgt tggtatcaat cgcaacatcc tcagctagac
     1021 tgatattttg ccccagtttt ccttgggcat acaagattgc aatattactt tgaagtggca
     1081 tatcacgatt caaacgattg tagaatacac ctgcaatgag cttacgatct tctgtcttgg
     1141 caccttcttt ttcgaccaag gaagcaatgg tcaacaactc attgacagtc aagtttttag
     1201 atttgatagt actatagtaa ggagataggt tcttatccat agcagctaac atctcatcaa
     1261 tcaagctctc aatagttgtg ctttccttga tagagtatgt agctgggaaa aggtatcctt
     1321 ccaaacgata acgcgcaccg ctgtctttta caggcaaact ttccagtaaa gtaggatatt
     1381 tcgctactgc ttgactgata aacgtctcat cttgaacttt agccaagaaa gcctccgctg
     1441 tcaaagactc tttgaagtca ccttgcaatt gacccacagt ttgagcaatc tgatccaagg
     1501 tataaccttc tggaattgtc aaagtcgcaa gtacaggttc ttgcggttca tctgttccac
     1561 ctttttgcaa ctctttgagt aagtcttctg tactcatact cttttgcaaa ttgtagtaac
     1621 ctgctttcaa gtcggtataa tttttatact tggcataaaa actaaaaatc agaccatgct
     1681 ttaccaaacc agctttttca agcgtcgtac cgatttcttg aacgtttgaa ccttctggaa
     1741 ttccaaccgt cacatatttc ttagaattag catcgatagg taataaggaa tctagcacgt
     1801 actggtaacc aaagtaacca cctgctgaga gcaaggcaag gaatacaagg aatgaaatca
     1861 caaaagcttt cacatgtgac ttcttctctt tcttaggctt aacgggtttt gctccttctc
     1921 tacggctacg acgtgatgta tctctgatga tatccactgt ttctgtagca ggcgtaggtg
     1981 tttctggacc tgcttgttct gcttttttct ctgccgtcgt ataggaaaca gctacccttg
     2041 ttggggtttc attgtattct ctttcaagtt tcttaggtct aacaggacct ggacctggtc
     2101 ttgatccact ttcttccgct ggagaagaag gtacatcttg acttggatga cttggaacac
     2161 caggagtttc tctttgaatc tcatctgctg gagaagctgg tacaccttga cttgggtgag
     2221 taggcacggt aggagctttt ctcataatct cctctaccgt tgacaaggaa tcagccatga
     2281 gttcttcagc tgaaggttca tttgcaggag tgcgaactac tgcctcatct tctttcagaa
     2341 cttcatcata gccttttact ttttctaaat ctctcagaat ctgctcttta aagcttaatt
     2401 tctcttcttc tcttgacttt tcactcaaaa gtttttcctc cttgttgata atccataata
     2461 ttatatctta aaagtccaaa aaaagcaatc tatgatactt ttcctaactt attttttcat
     2521 ttcccagacc atatcatacc atgtttcccc tgcaaaggtt gactgggact ggccttcgtt
     2581 gacaaatcca tgtttttcat aataggcgat gagatagtca tgacaggtta gattaatgcc
     2641 atctctctca tcttcaagag caacttcttt caaggctgtc agcaatttct gacccagtcc
     2701 gagtccctgt gcctccttgg caatagacag acaggtcaca gagatataac caccaggctc
     2761 atgactatag tcttttattt cttctgtaaa agactggtct tgcagatggc ggtgcaggcc
     2821 aactggtcct tcgatataac ccatgattct tccttctttt tcagcaacca gaaaagaggt
     2881 ctgaatttct ctcaaatgtg cttcaaagac agaaggagga atggcttctt cgaccgaaaa
     2941 attttcaaat tcaagttcaa caatccgatc caaatcttct aatcttgctt gtctgatttt
     3001 cattgttcct ccagataaaa gggattaaac caaatcatac tatagccctg gctagttgca
     3061 tagagcaaaa tttcttcttc atcaacaaaa ccgttcattt caaaatagga aagcagctca
     3121 tcaggactct ccaaacgaat ccctttgtaa tccagctcaa ctgccacctc tttcaaggct
     3181 gcaagaagaa gtgttcccag gccctgtctc tgatggtcag actcgatgac taaagaatgt
     3241 acttttagac attgcggatt gtctgactgg ggacttgata aaatatagcc taaaagttga
     3301 ttttcatccc tagctagaag aaaggtatcc gcacacttac ggatactttc ttctaaaata
     3361 tgggaaagtt gctgcttttc agctggaaaa gacgaggtct gaagtgcccc tatctcaggc
     3421 aaatcaaact tgcttgcctg aatgatctta attggaattt ccatgggaac atcctattga
     3481 acattgcttg tcaagttaga caagagacgc tcaaatgagt attcataggt ttggatgtct
     3541 cctgctccca taaagacgta aacagcattg tcatggtcta ggagtggaga aacattttca
     3601 acagtaatca cttggtgttt tttgttgatt ttattggcta ggtcttctac cttaacgtca
     3661 ccatgatcta cttcacgagc cgagccataa atttgcgcta gataaacagc atctgcttgg
     3721 tttaaagcat gggcaaagtc gtccaacagg gcaatggttc ttgtaaaggt atgcggttga
     3781 aagactgcta caatttcctt gcttgggtat ttctgacgag ccgcatccaa ggtcgcaata
     3841 atttctgttg gatgatgggc aaagtcatca ataatcactg tatcattgac aattttctca
     3901 gtgaaacgac gtttaacacc ggcaaatgtt ttcaagtgct cacgcaccaa gttcaaatca
     3961 aatcctgctg tgtaaagaag accaataacg gctgtcgcat tcatgatatt gtgacgacca
     4021 aaggttggaa tgtggaattg ccccaagttt tgtccacgga aatgaacggt gaaggttgaa
     4081 ccagttgttg aacgaagaag atcactagct acaaagtcat tgccttcagc ttcaaaacca
     4141 taataataaa ttggtgcatc agacgtaatc ttacgcaatt cagcatcttc accatagaca
     4201 aaaagaccct tggtaatttg tttggcatag tcgttaaagg cattgaaaac atcctcgaga
     4261 cttgtgaaat aatctggatg gtcaaagtca atgttggtga taatagagta ttctgggtgg
     4321 taaggcatga agtgacgctc atattcgtca gattcaaaga caaaatattt ggcattagcc
     4381 gaaccacgac ctgtcccatc tccaatcaag aagctggtat ctgtaatgtg agacaagaca
     4441 tgagacaaca tacctgtcgt tgaagttttt ccatgtgctc ctgctactcc catgctaaca
     4501 aagtcacgca taaagctacc tagaaactca tggtaacgtt tgtagctgat accattttgg
     4561 tccgcatagg caatttcgac gttgttatct ggacgaaagg catttccagc gataatttcc
     4621 atatcaccgt ctagattctt ttcatcaaaa ggaagaatgg taattcctgc ctgctcaaga
     4681 ccgcgttggg taaagtagta cttttcaaca tctgatccct gaaccttgtg ccccatctgg
     4741 tgcaacatca aggccaaggc actcatccct gatcccttaa ttccgataaa atgatatgtc
     4801 tttgacatgt tttctcccct attctgtcat tctggtcaga ttcaactctt gggcaacccg
     4861 acgttcttgt tctgtttgtt tacttttttt attgtagatt tggctcttct ttagaaaatc
     4921 ataattgttt ttctttggag caggtgctga cacttcttca ttcttggtag ggatagaatg
     4981 aacttcttcc gccaagatat aatgagactg ggtcaatttt tggctatatt tgacaaattc
     5041 accaggattt tccttttgga aaggagttgt cggttgattg ccctgtctaa ctagactggg
     5101 ctgagaatga cgtctcgcaa ggctgaaatc ctgagttagg tagttagcag agcgtttctt
     5161 tttcaagtcc gcacgcgctt cttcacgcgc cacctccgca tagctctttc cttctttttt
     5221 aacccctaaa ggagcctttt taggtttttc gacttgcttt tcaatcggtt ttactggttt
     5281 ttcttcagta ataggagccc attctaaata atttttatct cgatactcac ccttgatatt
     5341 actgatcaga tcagactcat catagagatt catgactggc atttcagtca acatgacctc
     5401 gtcatctgac accaatggaa atcgttcttg tttcattttc tatttccttt caacacttca
     5461 ttatagcgta ttgtcttgat ttttcaagtg ctggcttcag aaattcccaa aatttctcta
     5521 atttctgcta gggtcagact accacgtgac tctgtgccat ccaatacttg tgacaccaga
     5581 tgtttctttt gttcttggag ttcctgaatt ttttcttcaa tggttccctt ggtcaccaag
     5641 cgatagacct caaccgtttc ttcctgaccc atccgatggg cacggccaat ggcttgcgct
     5701 tccaccgcag gattccacca aaggtcaacc aagatcactg tatctgcacc tgtcaggttc
     5761 agaccgaccc caccagcctt gagggaaatc agaaaggcat ctctttctcc ttggttaaag
     5821 gccttggtca tgtcttgtct ttccttggct ggggttgaac ccgtaatttt aaaggatgtc
     5881 aggcccaagt ctggcagttc ttgttcaatt ttttccaaca ttcccttgaa ctgagagaaa
     5941 atcaagacac ggtgtccgcc gtctgccacc tgtaccagta gatctcggag actatctagt
     6001 ttgccgctgg ctccctgata atcttccata aacagggcag gagtgtcaca tatttgacgc
     6061 aagcgcatca aaccagataa aatttccaca cgacttcgct gaaattcctg ttctgacact
     6121 tgagccagat ggtctcgcat ctgttgtaac tgggcaaggt aaatagcctt ttgctggtct
     6181 tccagttcat ttttataaac cacctcaatc aagtctggca attcagtcag aacttcttct
     6241 ttcttgcgtc gcatcacgaa aggcttgata aactgagcca ctcgctctgc tggcaatttc
     6301 ataaattctt tcttgcttgg caaaagtccg ggcatgacga tttggaaaat agaccacaac
     6361 tcacccagat ggttttcaat cggagttcct gacaaggcaa agaccgacgg caccacaaat
     6421 tgtctcaagg tctgggcaat cttggtctgg gcatttttca tgacctgagc ctcatctaag
     6481 aaaaggaagt caaaggccat cccctgataa aactcactgt cctgacggaa ggtggcatag
     6541 ctagtcacat agatttgatg gctctcggca agaatctcct cacgacttgc tttcaaacca
     6601 tgaacaacag ccacatccaa ctgtggggca aatttctgaa actcatctgc ccagttgtaa
     6661 atcaaacctg acggagcgag aatcaaaacc cgactttctt ttgtcacttg actagtcaaa
     6721 aaagcaatgg tctgaagggt tttcccaagt cccatatcat cagccaaaat cccaccaaaa
     6781 ccataatgat ggagcatctg caaccagcca attccctttt cctgataatc tcgcaagtca
     6841 gcctgaacct gagttgcctg tcgaggaaag tcctctggat gtgtcaaatc ctgggccaga
     6901 ttctggaatt cttgtgaaaa agaaacacgg tctcgccctt caaagagatg agctaaactg
     6961 taggccaagg atttccgagc ctgcaaggtc ccatctttta attcaaattg ccccagttcc
     7021 tgtagatttt ggcgaatttt cttggtttct tcatcgaaaa agtaaacttg attagacgaa
     7081 tcaatataaa aatcctgatt ggcaaccaag gcctgcatgg cttggtcgat ttcctcctgg
     7141 gcaatatctt gaaaatcaaa ctggatttcc aagagacctc ccttggaggc aatctgcacc
     7201 tgaggactcg ctaggctata aagctcttct agtttatctg ataggtcaac atgcccgagt
     7261 ttttcaaaga ctggaatgat atcatgaaaa aaatgataga cagactccgc ttttaaggcc
     7321 tgacgccaag attgaaaatc ggcttcaaag cccgcagcca aacagacttg gaaaattctt
     7381 tcttctaagt ccgcgtcact tgaaaatggt aattcttcta gctcttgtcg gctagatacc
     7441 tgtctatttc cataatcaaa ctgaatttct aaacgaatcc gattatcttc ttccctgtca
     7501 aagtaaaaag agggcgcaaa agttttgatt tgtagacgtt ctggagctga aacggtgccc
     7561 atctggataa aaagagtcag acaggaggcc aatttgtctc gatcactgct atcaaattgc
     7621 aggtatttct ttccttgttg acccacaggt aacgctttaa tttccttgag aagacgcatc
     7681 tgctggtctg ttaaaaaata aacctgacct ttatggaaaa gtactgctcc ctgataaaag
     7741 acattgaccc taggactctc actgatttcc atttcaaaat agtccgagta ttctgttact
     7801 gcaaaggcaa atagattggc atcagcatgc atatcctgaa aaagcagggt ttggtagcta
     7861 tccacttgat ggtcaaattg aaaatggggc aaggccatca gtaaattcac accctgctca
     7921 aaaaaggtca gagggaaaaa gaggtgccga ccttggtttt ggaaaaagag gtctgaaacc
     7981 agcccttcct ccgttagtcc gtgcaagaaa gtcaaaagtt cttggctggc atcatcaaag
     8041 gcttcccaag aaagagactc ctcataaatc ttgccaatca tatacgactt tctctgctcg
     8101 acaatcctta aaaaaagtgg aatatcccga atgacatagt atttttggct attgatttgg
     8161 ccgattctca gagtccacaa gatatgattg gttcctgctt ccacctgacc cacagctgat
     8221 aactcatagg cgcattctga ttttggagat aaaattcgat ccaaaaactt gccacccaag
     8281 gtcaccttgg tttcaacagc ctctttttct tcatgacctt cttccagact ccacaagatt
     8341 tcctgaccac gctcatcatt tttcagaaaa tgctctagcg ctgccaaatg cacacagtaa
     8401 cccctctttt gaaaaaaatc acaggcacaa aaaaccaaat catcctctaa actatagcgc
     8461 agttcttctt ctgcaacgcg agcgtagagc cgattgttct tttccttgat gatatcaacc
     8521 ttaccagttt cataaagggc aacaccttcg atacgaattt tccccggaat caatttagcc
     8581 atattttcac ctttacctta tctttttatt ataccatatt ttcgcctatg aaaatagcct
     8641 tctaggaaga cttttctcct agaaggctgg atttttaacg t
//
LOCUS       DAVEHY010000059         7183 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVEHY010000059 DAVEHY010000000
VERSION     DAVEHY010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7183
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.059"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            317..6751
                     /locus_tag="VUZ44_002052"
     CDS             317..6751
                     /locus_tag="VUZ44_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU0320904.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         2804 a          988 c         1384 g         2007 t
ORIGIN      
        1 gactacgtca gttccatcta caacctcaaa acagtgtttt gagcaacctg cggctagttt
       61 cctagtttgc tctttgattt tcattgagta ctaatcttat tttttaacgt gtgctaaaaa
      121 ataaattaat gcatgttaat ttttcttgaa ttaaattttt ttaaatgata tactgttttt
      181 atggagagat aacaattata tataaatgta ctactctatt tcctagataa tacttagtaa
      241 aactttttat aacaaaggct agcaaagtta aagtttatta tctattggaa gttaaataaa
      301 tatgtaagga attaaaatga aaaaaagtac agtattgtca ttaaccacag ctgcagttat
      361 tttagcagcc tatgccccta atgaggtagt cttagcagac acatctagct ctgaagatgc
      421 tttaaacatc tctgataaag aaaaagtagt attagataag gaaacagaaa ataaagagaa
      481 acatgaagat attcataatg ctatagaaac ttcaaaggat actgaagaaa agaaaacaac
      541 agttattgag gaaaaagaag ttgttagtaa aaatcctgtg atagacacta aaactagcaa
      601 tgaagaagca agaatcaaag aagattccaa tcaatcccaa ggagataatg cacactcgtc
      661 tgcaaataaa ggcacagaaa atccgaaaaa agaagataga cttgtctata ttgctgaatt
      721 taaagataaa gaatctggag aaaaagcaat caagcaacta tccaatctta agaatacaaa
      781 agttttatat acttatgata gaatttttaa cggtagtgcc atagaaacaa ctccagataa
      841 cttggacaaa attaaacaaa tagaaggtat tacatcggtt gaaagggcac aaaaagtcca
      901 acccatgatg aatcatgcca gaaaggaaat tggagttgag gaagctattg attacctaaa
      961 gtctatcaat gctccgtttg ggaaaaattt tgatggtaga ggtatggtca tttcaaatat
     1021 cgatactgga acagattata gacataaggc tatgagaatc gatgatgatg ccaaagcctc
     1081 aatgagattt aaaaaagaag acttaaaagg aactgataaa aattattggt tgagtgataa
     1141 aatccctcat gcgttcaatt attataatgg tggcaaaatc actgtagaaa aatatgatga
     1201 tggaagggat tattttgacc cacatgggat gcatattgca gggattcttg ctggaaatga
     1261 tactgaacaa gatatcaaaa actttaacgg catagatgga attgcaccta atgcacaaat
     1321 tttctcttac aaaatgtatt ctgacgcagg atctgggttt gcgggtgatg aaacaatgtt
     1381 tcatgctatt gaagattcta tcaaacacaa cgttgatgtt gtttcggtat catctggttt
     1441 tacaggaaca ggtcttgtag gtgagaaata ttggcaagct attcgggcat taagaaaagc
     1501 aggcattcca atggttgtcg ctacgggtaa ctatgcgact tctgcttcaa gttcttcatg
     1561 ggatttagta gcaaataatc atctgaaaat gaccgacact ggaaatgtaa cacgaactgc
     1621 agcacatgag gatgcgatag cggtcgcttc tgctaaaaat caaacagttg agtttgataa
     1681 agttaacata ggtggagaaa gttttaaata cagaaatata ggggcctttt tcgataagaa
     1741 taaaatcaca acaaatgaag atggaacaaa agctcctagt aaattaaaat ttgtatatat
     1801 aggcaagggg caagaccaag atttgatagg tttggatctt aggggcaaaa ttgcagtaat
     1861 ggatagaatt tatacaaagg atttaaaaaa tgcttttaaa aaagctatgg ataagggtgc
     1921 acgcgccatt atggttgtaa atactgtaaa ttactacaat agagataatt ggacagagct
     1981 tccagctatg ggatatgaag cggatgaagg tactaaaagt caagtgtttt caatttcagg
     2041 agatgatggt gtaaagctat ggaacatgat taatcctaat aaaaaaactg aagtcaaaag
     2101 aaataataaa gaagatttta aagataaatt ggagcaatac tatccaattg atatggaaag
     2161 ttttaattcc aacaaaccga atgtaggtga cgaaaaagag attgacttta agtttgcacc
     2221 tgacacagac aaagaactct ataaagaaga tatcatcgtt ccagcaggat ctacatcttg
     2281 ggggccaaga atagatttac ttttaaaacc cgatgtttca gcacctggta aaaatattaa
     2341 atccacgctt aatgttatta atggcaaatc aacttatggc tatatgtcag gaactagtat
     2401 ggcgactcca atcgtggcag cttctactgt tttgattaga ccgaaattaa aggaaatgct
     2461 tgaaagacct gtattgaaaa atcttaaggg agatgacaaa atagatctta caagtcttac
     2521 aaaaattgcc ctacaaaata ctgcgcgacc tatgatggat gcaacttctt ggaaagaaaa
     2581 aagtcaatac tttgcatcac ctagacaaca gggagcaggc ctaattaatg tggccaatgc
     2641 tttgagaaat gaagttgtag caactttcaa aaacacggat tctaaaggtt tggtaaactc
     2701 atatggttcc atttctctta aagaaataaa aggtgataaa aaatacttta caatcaagct
     2761 tcacaataca tcaaacagac ctttgacttt taaagtttca gcatcagcga taactacaga
     2821 ttctctaact gacagattaa aacttgatga aacatataaa gatgaaaaat ctccagatgg
     2881 taagcaaatt gttccagaaa ttcacccaga aaaagtcaaa ggagcaaata tcacatttga
     2941 gcatgatact ttcactatag gcgcaaattc tagctttgat ttgaatgcgg ttataaatgt
     3001 tggagaggcc aaaaacaaaa ataaatttgt agaatcattt attcattttg agtcagtgga
     3061 agaaatggaa gctctaaact ccaacgggaa gaaaataaac ttccaacctt ctttgtcgat
     3121 gcctctaatg ggatttgctg ggaattggaa ccacgaacca atccttgata aatgggcttg
     3181 ggaagaaggg tcaagatcaa aaacactggg aggttatgat gatgatggta aaccgaaaat
     3241 tccaggaacc ttaaataagg gaattggtgg agaacatggt atagataaat ttaatccagc
     3301 aggagttata caaaatagaa aagataaaaa tacaacatcc ctggatcaaa atccagaatt
     3361 atttgctttc aataaccaag ggatcaacgc tccatcatca agtggttcta agattgctaa
     3421 catttatcct ttagattcaa atggaaatcc tcaagatgct caacttgaaa gaggattaac
     3481 accttctcca cttgtattaa gaagtgcaga agaaggattg atttcaatag taaatacaaa
     3541 taaagaggga gaaaatcaaa gagacttaaa agtcatttcg agagaacact ttattagagg
     3601 aattttaaat tctaaaagca atgatgcaaa gggaatcaaa tcatctaaac taaaagtttg
     3661 gggtgacttg aagtgggatg gactcatcta taatcctaga ggtagagaag aaaatgcacc
     3721 agaaagtaag gataatcaag atcctgctac taagataaga ggtcaatttg aaccgattgc
     3781 agaaggtcaa tatttctata aatttaaata tagattaact aaagattacc catggcaggt
     3841 ttcctatatt cctgtaaaaa ttgataacac cgcccctaag attgtttcgg ttgatttttc
     3901 aaatcctgaa aaaattaagt tgattacaaa ggatacttat cataaggtaa aagatcagta
     3961 taagaatgaa acgctattcg cgagagatca aaaagaacat cctgaaaaat ttgacgagat
     4021 tgcgaacgaa gtttggtatg ctggcgccgc tcttgttaat gaagatggag aggttgaaaa
     4081 aaatcttgaa gtaacttacg caggtgaggg tcaaggaaga aatagaaaac ttgataaaga
     4141 cggaaatacc atttatgaaa ttaaaggtgc gggagattta aggggaaaaa tcattgaagt
     4201 cattgcatta gatggttcta gcaatttcac aaagattcat agaattaaat ttgctaatca
     4261 ggctgatgaa aaggggatga tttcctatta tctagtagat cctgatcaag attcatctaa
     4321 atatcaaaag cttggcgaga ttgcagaatc taaatttaaa aatttaggaa atggaaaaga
     4381 gggtagtcta aaaaaagata caactggggt agaacatcat catcaagaaa atgaagagtc
     4441 tattaaagaa aaatctagtt ttactattga tagaaatatt tcaacaatta gagactttga
     4501 aaataaagac ttaaagaaac tcattaaaaa gaaatttaga gaagttgatg attttacaag
     4561 tgaaactggt aagagaatag aggaatacga ttataaatac gatgataagg gaaatattat
     4621 tgcttatgac gatggtagtg ccttacaata tgaaactgaa aaacttgacg aaataaaatc
     4681 aaaaatttat ggcgttctaa gcccatctaa agatggacac tttgaaattc ttggaaagat
     4741 aagcaatgtt tctaaaaatg ccaaggtata ttatggaaat agctataaat cgatagaaat
     4801 caaagcgact aagtatgact cacattcaaa aacgatgaca tttgatttat acgctaatat
     4861 taatgatatt gtggatggat tagcttttgc tggagatatg cggttttttg ttaaagatga
     4921 taatcgaata aaagctgaaa ctaaaattag aatgcctgaa aaaaataagg aaactaaagc
     4981 agaatatccc tatgtatcaa gttatgggaa tgtaatcgaa ttaggagaag gagatctttc
     5041 aaagaacaaa ccagacaatt taactaaaat ggaatctggt aaaatctatt ctgattcaga
     5101 aaaacaacaa tatctgttaa aggataacat cattctaaga aaaggctatg cactaaaagt
     5161 gactacctat aatcctggaa aaacggatat gttagaagga aatggagtct atagcaagga
     5221 agatatagca aaaatacaaa aggccaatcc taatctaaga gtcctttcag aaacaacaat
     5281 ttatgctgat agtagaaatg ttgaagatgg aagaagtacc caagctgtat taatgtcggc
     5341 tttggacggc tttaacatta taaggtatca agtgtttaca tttaaaatga acgataaagg
     5401 ggaagctatc gataaagacg gaaatcttgt gacagattct tctaaacttg tattatttgg
     5461 taaggatgat aaagaataca ctggagagga taagtccaat gtagaagcta taaaagaaga
     5521 tggctccatg ttatttattg ataccaaacc agtaaacctt tcaatggata agaactactt
     5581 taatccatct aaatctaata aaatttatgt acgaaatcca gaattttatt taagaggtaa
     5641 gatttctgat aagggtggtt ttaactggga attgagagtt aatgaatcgg ttgtagataa
     5701 ttatttaatc tacggagatt tacacattga taacactaga gattttaata ttaagctgaa
     5761 tgttaaagac ggtgacatca tggactgggg aatgaaagac tataaagcaa acggatttcc
     5821 agataaggta acagatatgg atggaaatgt ttatcttcaa actggctata gcgatttgaa
     5881 tgctaaagca gttggagtcc actatcagtt tttatatgat aatgttaaac ccgaagtaaa
     5941 cattgatcct aagggaaata ctagtatcga atatgctgat ggaaaatctg tagtctttaa
     6001 catcaatgat aaaagaaata atggattcga tggtgagatt caagaacaac atatttatgt
     6061 aaatggaaaa gaatatacat catttgatga tattaaacaa ataacagaca agacactaaa
     6121 cattaagatt gttgtaaaag attttgcaag aaatacaacc gtaaaagaat tcattttaaa
     6181 taaagatacg ggagaggtaa gtgaattaaa acctcatagg gtaactgtga ccattcaaaa
     6241 tggaaaagaa atgagttcaa cgatagtgtc ggaagaagat tttattttac ctgtttataa
     6301 gggtgaatta gaaaaaggat accaatttga tggttgggaa atttctggtt tcgaaggtaa
     6361 aaaagacgct ggctatgtta ttaatctatc aaaagatacc tttataaaac ctgtattcaa
     6421 gaaaatagag gagaaaaagg aggaagaaaa taaacctact tttgatgtat cgaaaaagaa
     6481 agataaccca caagtaaacc atagtcaatt aaatgaaagt cacagaaaag aggatttaca
     6541 aagagaagat cattcacaaa aatctgattc aactaaggat gttacagcta cagttcttga
     6601 taaaaacaat atcagtagta aatcaactac taacaatcct aataagttgc caaaaactgg
     6661 aacagcaagc ggagcccaga cactattagc tgccggaata atgtttatag taggaatttt
     6721 tcttggattg aagaaaaaaa atcaagatta agacaaaagc tatagaaaaa aatggtttat
     6781 gtactgagat tagatagtga ggtgatgaca tagttttgtg aaaacggcca tttataactc
     6841 aattatttag tttacttcac ttcactattg atactatttg gagttattaa tggacttagt
     6901 ttagataact aatgaattga ttgaaagggt tagtattgac aatattggtc atattgatta
     6961 gaaaatagag tctatcaaaa tttaaaggct aatagaggtg atgagacaat ttcaaggaat
     7021 taagtagcgt ttggttgctt aattcctttt tatttggaag gaagtttttc gtaaccgccc
     7081 aataacgaag tctattggac ggttacgata tgatcactga cttcgtcagt cttatctaca
     7141 acctcaaaac tgtgttttga gcaacctgcg gctagcttcc tag
//
LOCUS       DAVEHY010000060         7097 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVEHY010000060 DAVEHY010000000
VERSION     DAVEHY010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.060"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(38..1429)
                     /gene="argH"
                     /locus_tag="VUZ44_002053"
     CDS             complement(38..1429)
                     /gene="argH"
                     /locus_tag="VUZ44_002053"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU0320905.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAYHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TIGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(1458..2654)
                     /locus_tag="VUZ44_002054"
     CDS             complement(1458..2654)
                     /locus_tag="VUZ44_002054"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU0320906.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQIGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKEN
                     GVPIPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPSSLYDENLATYTSADTFDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            complement(2671..3477)
                     /locus_tag="VUZ44_002055"
     CDS             complement(2671..3477)
                     /locus_tag="VUZ44_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU0320907.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3684..4325)
                     /locus_tag="VUZ44_002056"
     CDS             complement(3684..4325)
                     /locus_tag="VUZ44_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU0320908.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4322..6430)
                     /locus_tag="VUZ44_002057"
     CDS             complement(4322..6430)
                     /locus_tag="VUZ44_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU0320909.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHALLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6482..6769)
                     /locus_tag="VUZ44_002058"
     CDS             complement(6482..6769)
                     /locus_tag="VUZ44_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU0320910.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
BASE COUNT         2135 a         1622 c         1173 g         2167 t
ORIGIN      
        1 caatcgacca acctcttatt ctgaacccat cactccatca ctttttagct tcattcgctt
       61 tcttagcgac tgcaatctgg tattcgactt ggtcaaaccc tgtgcctccc aaggaatttc
      121 gtctttgaac agcagtttta ggttgcaagt agacatagat atcctcggta atgagagaat
      181 gataggtttg taattcctcc aaagtccaat cttgaagatt tttagcagac ttgatagagt
      241 ctagcactaa tcttcccaca acctcatgag cttctctaaa tggcaagcct ttccctgcca
      301 aataatctgc caactcagtt gcatttgaaa agtccttctc tgttgattct tgcatttttt
      361 ccttgtttac ctgcaaacta gataacatac ctgccaacac atcgagggaa tttaaaatcg
      421 tttcgaccgt atcaaacatt ccttccttat cttcttgcaa atccttatta taagctaaag
      481 gcaaggactt catgactgtc aacagtccaa acaaatgccc ataaactctg ccagtctttc
      541 ctcgaatcaa ctcagccata tctggatttt tcttttgggg cataatagag gaacctattg
      601 taaacgtatc tgacaaggta atgaattggt actcaaaact acaccaatta atcatttctt
      661 cgcaaaaacg actcatatgc atcatgagta tgctggcatt tgatagaaat tctaagataa
      721 aatcgcggtc actaacagca tccaaagaat ttgtataagg ttgcttaaac tccagcaaat
      781 cgctagacaa ttggcgatca atggggaaag tcgttcctgc caaagctgcc gcacctaaag
      841 ggcataggtc tgtatgcttc tggttaaatt caaaacgttc actgtctctt tgaaacatat
      901 tgtagtaagc catcaggtgg taggcaaaac taataggctg ggcatgttgc agatgggtat
      961 agcccggcat gatcgtcgcc acatgatttt ccgccaagtc taataaaaca cccttaagat
     1021 gagccagttt atctaggaca tagcctagtt gttccttgag atacaagtgc atatctgtcg
     1081 caacttggtc atttcgagaa cgagccgtat gtaacttccc tgcaagggga ccaatttttt
     1141 ctgtcagcaa cacttccata ttcatatgaa tatcttcgtt tgcgatatca aagtcaagtt
     1201 gacctgcctc tagctcttct aaaagctctt tcaagcctac ttgaatcttt tctgactcct
     1261 ccaaactcaa aatgcccgtc tgacccaaca tctgaacgtg ggctaaagaa ccaatcacat
     1321 caaatttagc taatttctgg tcaaaagata tactcgcacc aaagcgctct acccagtctt
     1381 cgacagtacc ttcaaagcga ccaccccata attttgtatt cttagccata tcacatccac
     1441 ctctctatcc aatcgtccta tttggcgctt ttttgaacct cagaatgaac cttggttgga
     1501 agtccccata acttaataaa gccaacagcc gcatcttggt caaaggtatc tgcactagta
     1561 tacgtcgcca aattttcatc gtaaagagaa cttggtgatt tccgagccac gacctgagcg
     1621 ctccccttat acagtttgac ttttgcagtc ccattgacaa ctttttgagt ctctttaata
     1681 taagcaatca aggcttgtgt agccgaacta aaccacaaag cattataaat gagatttgat
     1741 aattcatttt ctatgattgg tttaaaatga gccacttctc tcacaagcgt caagtcctca
     1801 atttccttat gagctgtcag cagggtcact gcacctggac actcatagat ttctcttgat
     1861 ttaatcccaa ccaagcgatt ttccacgtgg tcaatccgtc caaccccatg ttttccagct
     1921 atttcattga gtttttgaat caaatctgcc aattttaaca cttctccatt gagggaaact
     1981 ggaacacctt cactaaactc aatctcaatg tattctggca tatctggagc ttgctctgga
     2041 gaagttgtga tgccaaaggc ttcttctgga gcctgattcc atggattttc caaaatacca
     2101 cactcattgg cacgtcccca aagattttgg tcgacagagt agggattgtc aaggtcagca
     2161 ggaataggca ccccattttc cttggcataa taaatttctt cctcccgaga ccatttccat
     2221 tcacgaactg gagcaatcac ttttaaattg agatccaagg ctgcaatcga tacttcaaaa
     2281 cgtacttggt cattcccctt accggtacaa ccatgagcaa ttgtagtcgc tcctatctga
     2341 tgcgctattt caaccaattt tttagaaatc agagggcggc tcaaggcaga taccaaggga
     2401 tacttttgtt cataataggc atgtgactga tgagccacta gcacataatc tgtagcaaat
     2461 tcgtccttaa catcaatgac ataagattcg actgccccaa ccttaagagc cttatcatgg
     2521 atgaaatcta agtctttccc ttcacccaca tccatacaaa ctgcaacaac atcatagtct
     2581 ttcttcagcc aggtaatagc aactgatgtg tctaaaccgc cagaataggc caaaattact
     2641 ttttctttac tcatgttctt ttccttcttt ctatttttca atggacgctt taaaggcatc
     2701 ctcaatgagt ttgtctaatt ccccagactc cttcaacttt tgaatggttt tatcgactgc
     2761 ctctttcaat tccttgctat cttttttcat ggctaccgca taggaatcat cttgctcttt
     2821 ttcaaaattg aggtctgcga ttgctaaatc aggattattt tccacaaatc ccttggcaac
     2881 gggttcttca aaaataacgg catccacttg ccctgatttt aaatctgtga ttaaattccc
     2941 atttttaggc agagatacga gggaagaatt ttgtagcaaa tctttcgcca tcgtctcttg
     3001 aatcgaacct ttctgcgctc cgaccttttt ctgcgccaaa tcgttgacag actgataagt
     3061 ggctaaatca gattttttga caatgagttt attttttgca gtatagtagg gagttgaaaa
     3121 atcaaacacc ttgctccgtt catctgtctt agaaacacct gatatggcaa ggtcagcttt
     3181 tcctgattga acgctagcca gtacattgtc aaaactcata ggagatagtt ccaattcgac
     3241 acctagttct gttgcgatag ccttggctaa ttcgatatct gaacccacaa tctgattttt
     3301 cccatcaacc actttttggt attcaaatgg agcaaaatct ggattgaggg ctacaaccaa
     3361 ttttcctttg gacttgatgg cttcaattcc agccgattga ttgttgctac aagcaaatag
     3421 tagggggagc atcactaaac caaacatcgt catcaacacc ttcttcatct tattcataac
     3481 aaagtctcct ttatgtttat tctttttggt tgtataaata atactcctat actcatcctt
     3541 tgtcaagcct aaattgaaaa aattttcaat ttgaaacaaa aaaaacctag aaatactaca
     3601 taaaatgtca ttcctaggcg tatttatgct atttttctct ggaaaacatg agtattcagc
     3661 cagtcaaaag gagctgaatg aactcatttt ccctcgccca attcaatgac acgatgacat
     3721 tgttgggcta cataagcatc gtgggtcacg ataatgactg ttttcccttc tcgattcatc
     3781 tctaagagaa acttcaagac caaatctcta ttttcaggat ccagcgaacc tgtaggttca
     3841 tcggctaaaa tcagctggct gggttttaag atggctctag caactgcaat tcgttgttgt
     3901 tcgcccccag acaactcgga gaccctttga tgcaaagtag ctgacaaacc tactctctct
     3961 aaaatctctt ccaccttttt gagcttgtct ttcttaggca atttcacata tttcagcgcc
     4021 agcatgagat tgtactcgac cgtttcatca tcaatcaggg caaaattttg aaacagataa
     4081 gagatatgtt cacggattat tgtttgcgac ttagcagaat taaccgctag atttgtctga
     4141 ccaaaaatct cataccgtcc gctataatca ccatctatca aacccaataa atttaacaag
     4201 gtcgacttcc cactaccact cttaccaaca atagctacca aatccccctg atcaatcctg
     4261 agagataagt tatccaaaat cacttttccc ccaatggttt tggtaatatt tttcaactca
     4321 atcataagat gccccctttc aataactcta ctagacttct tttctccatc ctagaagcta
     4381 agcctagcac aaatagtata tccagacatg taaaacctgc aaacagcagg agtggcaaga
     4441 gcgcatgggc aaagaaaatc aagactagaa gagggaaact atagcccagc aagagcagaa
     4501 cgaggagagg acggtagcga tcgaccagtt tccaccccat aaacttcttg gtaatgatat
     4561 ccctgcgctt caataagaaa gttgttacta gtaagaagta ggaaatcatc atgctaagga
     4621 gaccaaacaa agcaaagagt aggttaaaat tccgaacagc atctcgataa gaatccactt
     4681 tctcttgttg aatggcttga atagatgaaa attttaaata atttccatct gacaatttct
     4741 caactaactc tgtaatctct ttttgatgtt gaaccgtatt ttcaatttta atcggattat
     4801 ttaagccagt tgttgacagg gaggctttct catcccacat catatcagaa tcattgacca
     4861 agctaataat tggattggag agattttcct ttcgcttatc actatatggg aaaaatgacc
     4921 aatctccttc ataataggca atctcgacat ccatctcctc tatcgttcgt ttttgctgct
     4981 cttcatactt catcgaatga aaggcaatta acttccccaa gagctgattt ttatcttctt
     5041 cacctttcgt acttgctggc atcaaaataa cttttttaat accggtatct ggtagcttga
     5101 atcccttgct ctttagaaaa ttgcgattgg catagtaaac atccaccgta tctgttaact
     5161 gatattgctg aatctgttct gattggacaa aattttttac aggaagactg ctactctgca
     5221 catagcccgc ctgcgttttt tctaccaaat cctgataaaa tcgatagaaa taatctgtag
     5281 atttccctga ccctgctagc tcttcttgcc acagattatc attgagtttg aaggtttcta
     5341 aggtcaggta attaccttga cttacccact gttgctgata agcaagttct ttgttttctt
     5401 gttctaaact tctgcccacc ccaatcagta aggccgtcag taaaatagtt gtccctattt
     5461 tcatcacata attgaagata agaccaaatt tgaaagatga aaaacctttc agcagagagc
     5521 tgattgtcat tttttggatt aagaggtaag tcaaccaact gataaagaga taaagctgca
     5581 acagcaaaaa atgagacaac cacagcatag gaaacaaatc ttttggctta taatcaagca
     5641 agaaaaacac gcctagattg atcacaagag ccccacctag gaggaggtaa aggttgcctt
     5701 ttacaacatc agctaaaaca gccctatctt gaaaaccaag taatttttgt accccaactc
     5761 ttttcatctc catcatcggt tgatacactg tcactaacac aagaagcaaa atagccaaga
     5821 caaaaacaat ggcagataaa agcaaatctc gatttatgac ttccactgca cttttgtagg
     5881 tcggctctag caaggtagcc tggtctatct tgaaaaaatc gctccatttc tgtacaatcc
     5941 tatccttgtc catctcttgt gtagaagtta tcgtatagcg accatttaaa ctacgagatg
     6001 tatccttgat ataggtttga aaagtcataa gctgaatagg tttggctttt agaaaggtcg
     6061 gaatcgtacc aagtttattg gaaatttctt tattactata gactccttca ccatctgtgg
     6121 taaaatcaag agaagaaatc ccaaactctt ggtaggggaa ggtatcttta tcaaaaacac
     6181 cagacttgac cacctcatca ccactgtctg ttttgatgat ggagacttta tactcctttg
     6241 atacatcctc aaaaaatcga agaacagacg ctgcaggttc gttaatatct ttcaaataca
     6301 aatccaaaga atctacagtc tttcccattt cttgaatccg aaccacttct cgtgtatagt
     6361 ttacattaaa aacaaaaaaa gtggtacaca gaagcaggag taacatacag aaattactga
     6421 tttttttcat aaaagtgcct ccactacagt tttccctctc caaataggag agggaagaat
     6481 tttactcaaa tccatagaaa tattccattc ctgttggcgg aatcttggtg agggaagctc
     6541 tagcccatgc ctcaggtttt gcataatcct tagaggttct acccccatgt ctaacagttg
     6601 ctgtatgata tcgagtagaa tgtaagtaat cagaatatcc aaaagttcct gtccaaccta
     6661 ctccatagtt ccattgacca ccctcaaccc atactgctaa agcatttgta gtagcaagta
     6721 taccacatac cattaaagat gcaacaccaa ttttaactaa ttttctcatg atttatttct
     6781 tctattatcg agagctgttc cgtaaaaaca gctatagtaa tttatcaaca agtatcgtag
     6841 tccattggac tcaccttcct tctatctcat ttcatttttt aacaacgaac ttactcttaa
     6901 ccgggagaat ggtgcgcttc tgtatcaggt ccttgaacaa ccagagtagt attaagcaca
     6961 ctctaactat tactcaagaa tcagtccaat aaacaatatg gatagcgctt tcaaattttt
     7021 aaactcctat cccgtccttt tatctatata ataagtgaaa atataataac tgtcaagtaa
     7081 tcgaagtgaa ttttata
//
LOCUS       DAVEHY010000061         7030 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVEHY010000061 DAVEHY010000000
VERSION     DAVEHY010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.061"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            108..407
                     /locus_tag="VUZ44_002059"
                     /pseudo
     CDS             108..407
                     /locus_tag="VUZ44_002059"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(685..1455)
                     /locus_tag="VUZ44_002060"
     CDS             complement(685..1455)
                     /locus_tag="VUZ44_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU0320911.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGYLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(1470..2096)
                     /locus_tag="VUZ44_002061"
                     /pseudo
     CDS             complement(1470..2096)
                     /locus_tag="VUZ44_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            complement(2002..2604)
                     /locus_tag="VUZ44_002062"
     CDS             complement(2002..2604)
                     /locus_tag="VUZ44_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU0320912.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSTGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            complement(2614..2931)
                     /locus_tag="VUZ44_002063"
     CDS             complement(2614..2931)
                     /locus_tag="VUZ44_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU0320913.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(2948..3265)
                     /locus_tag="VUZ44_002064"
     CDS             complement(2948..3265)
                     /locus_tag="VUZ44_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU0320914.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(3280..4176)
                     /locus_tag="VUZ44_002065"
     CDS             complement(3280..4176)
                     /locus_tag="VUZ44_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU0320915.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(4179..5441)
                     /locus_tag="VUZ44_002066"
     CDS             complement(4179..5441)
                     /locus_tag="VUZ44_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU0320916.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            5721..6899
                     /locus_tag="VUZ44_002067"
     CDS             5721..6899
                     /locus_tag="VUZ44_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU0320917.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT         2451 a         1473 c          995 g         2111 t
ORIGIN      
        1 agtttctata gtaaaatgaa ccaaaaatag tacacgttgc ggtataatgt tcttgtggca
       61 tattcattag attttcgtaa aaagttctct cctatttgtg agcgaacagg tatagtcaat
      121 tgattgtcag tttgaagacc aagagtcgta aggcaaagga tatggcagaa tccatccaag
      181 ggtggctggc acaatttcta gtgaacctct ttaaatctat tacgtttgac tgtggaaaag
      241 agttttcaaa atggaaagat atttccaatc atcacgatag tgagagcttt tttgcgaatc
      301 taggatgtcc aagacagcgg tgtctcaacg aacattcaaa tagactttta aggtgtcatg
      361 acttgccaaa gcagacagat ttcaacgaag tcagtcaaga attttaggct gggtaaaaac
      421 tcaatttcag gagaaaatga aataaatatt cccacaataa aacgcatagt atcaaagttt
      481 ttccaacacc tgatattata cattttttaa ttttaaagac tttttcccag cctcaagaaa
      541 tcacatccca cctaaatcct ttggatacca aatacctcat caggtatttt ctgagttggt
      601 aagactgtct agcttaattt gacaaatgga gggcgttaaa tccagttttt acaggaagtc
      661 tatttaaata ttttcacact gaccttacaa aatatgaaat aaattatata aagtcattcc
      721 catgacaaag aataacatcc ctttaaaaca gtatcttacc caattttcag gtaagacttt
      781 tgatacaacc gtccccaata cccctccgca tatagaagca agaaaaataa ctggaacagg
      841 tgctaaatga tactgattta aacctgtaac cacaacaatt gtagccaaat gagacagctg
      901 ggaaaagaaa ataattgcaa gagaatacat cgttgcttct tttatcgaaa tagaaaaaaa
      961 caccatcaat aaagatacat tgagcggacc accaccaatc cctaaaaaac tagaaatcaa
     1021 gcccaataga agaccacaaa tcatatagaa tcctatctta tcaaattgat aagttttttt
     1081 aaaatctgtt aaaacaaatg atacaagtaa catcacaaat agtaaaatca tttgaacaat
     1141 agatactagc cgtactgata attgagataa caaaacttga aaaataagat aacctagaaa
     1201 tcctcctaaa acagaagaaa aggataccgt aaaaatcaat ctccatttta tctctttact
     1261 ttgtgaaaat cttttgattg ttgaaataat cgccattata aaaacagaga aactagaata
     1321 aaaagcaata tcactgaccg aatggtatcc aaaactatcc ataagtggct taattataat
     1381 tccaccaccc atgcctgata tagaacccaa tccactagct attataatga ttagaaaata
     1441 aataatctca accacttttt aagtccatcc tattctttca aacatctaaa acctagatgg
     1501 ctactagtgg aagtagaaat acatccattt ctagcagcta ctcggtatcg attacaataa
     1561 gaacaatgac ataaaaagga acctcctctg atagcatact cctcatcttg tatcccatat
     1621 tttggtaact catagtcatc ttcattaaaa ctagctaata aggtatatct cggattgcga
     1681 caccattccc aaacattccc aatcatttga tatagaccaa aatcattagg taaaaattca
     1741 tagacaggag ccgttcctat aaatccatct aaggcagtat tttcataagg aaatcttcct
     1801 tgccaagtat tggcatgata atatccacct tctaaaagag tatctcccca aagatattca
     1861 gattgtcttc ctcctctagc agcatattcc cactgtgctt cagtcggtaa agacattccg
     1921 ctccaattac agaaagccaa tgcatcttct aaagcaacat gaactactgg atggtcttct
     1981 aaacccacta gattactgtt ctcaccgtag ggatgtttcc agcaagcgtt cggaacttgt
     2041 aaccaccacg gagccccagc aggatgagga tatccctccc tttctgcctc tggcattaat
     2101 atggtttcct ggaatcacat tcccaatagt taccatcaga tttttaccat caaatgctag
     2161 attatcaatt ccttgtaaga tctgatctaa tttcacatct cctacatttg ccaaagggaa
     2221 actctttgta actgtacttc caatcgaaat gacaaacgaa gcaagtgata ccaaaccagt
     2281 agaaactgta tcaaccttgt aaatcttagc gatattcact cccaagcaat agatgaacaa
     2341 caaggaaaca attggtatac ttcccttgaa taccaaatta ttgatgtcaa caagccactg
     2401 aaaggttttc gtaatacttt ctaggtgaaa ttgttgtggt aaatccacta gaaaagcatt
     2461 taataacaaa gcaatggaac ctgtcataat aacaggcata gtccccacaa atgaatcacg
     2521 taaagcaact aaaaacttct gattcccaac tttcattgca attggagaaa gtttttcttg
     2581 cattttatcc aacattgtat tcataccaaa ctcctaattt ttttcaaatc gttcgtatac
     2641 ttctaccact tctttcgcca agtcaacaaa agtcagactc gtcattaaat gatcttgcgc
     2701 gtgtaccatc aagaggctaa ttgatgtttt ttccccctgt gcctctcttg tcaacatttc
     2761 tgtttgagcc ttatgcgcct gtaataaggc agcattcgca tcagctaatc ttcgattggc
     2821 tttagagaaa tccccttttt ttgctgcctg aatagcctcc atagcattac ttttggcttc
     2881 cccaccatac ataattagcc ccattacaga ttctaaatta ctttcatcca taacattctc
     2941 ctcaatctta gtctaataaa ctttcagcta aatctaaaac tttagaacca ttcatcattc
     3001 cgtaatctgt catcggaata accgccacag gaatctgtct atcttttagt ttttcttgaa
     3061 agtcccctag taaatagcga acttgaggac ctaaaagcaa cacatttact tcttttgttg
     3121 ctacaatttc ttctgcttca ggagctggaa ctgcaaaaat ttctgcatcc aaccccttat
     3181 cttctgctgc cttttgcatc tttgtcacta gcagacttgt actcatacct gctgcacatg
     3241 ctaacataat tgttacttta gccatagctt actcctttat cacctattta ctgacctagc
     3301 caagcgagat actgtatgtc tcactcctct aattgccttg ctcaatgcat aaatattatc
     3361 gactgttgcc agtcccccat atcctgcgtc acctatatgt tgaatatcaa ctccacaaat
     3421 tttatttcta agtgcaattt ccttgatagt atctgtatca gatgtttctt ggctagtacc
     3481 aatagcactc aatacaagac cacccttact atgaacgaga tcaacgactt cacgcaactc
     3541 ttggtcatga aaggctggaa cggttccaac tgctggaaca agtatcacat ccgcacctgc
     3601 ttccaacaat tgctctgcga cagaaagctc tgccacaggc tcattcactc ctgccccgtg
     3661 cattttacca gctataatca aacctgagaa attctcttta gcagattgaa ctgctttgat
     3721 aatctcttga ttgctaactc ctgttccagg atttccagtc aaacagacaa agtcaaaacc
     3781 taactcctct attcgattca atgtttcaac actagcaaca cgacctgcaa caatttcctg
     3841 tgtttcctct agcatctttg cagatgggtc aatcggttcc aaatttacac caattggaca
     3901 agcaacaagc tggtgtaagc gatgaataac atcatcacct gaactatcca aagcataaat
     3961 tttaggctca aaaacatcaa cacaattcaa taaaatcata tcagctccaa aagctctagc
     4021 aatttcagaa ttagttatat ccccaacaaa tgtctcacga gtaactacat tttcagatag
     4081 aacaactcta ccttcacttg ctaaaatact ttgttttaat tcttcagcat tcatctgtaa
     4141 tatctcagat ggatttgcac taattaaacg tttcattctc aatcctccaa taacttaaac
     4201 cgtttttcaa tagctattac aaatggtaaa taaagtaaga catccaaaac aatcaataca
     4261 atttgtaata atgaaccaga aatacttcct gtagcaagta aaccacttat aacaggtggc
     4321 atagtccaac ctggatctgt ataagttagc ggaaccaaac ctgatgccat tgctccccac
     4381 gctactagta agttaaacat tggagctaag ataaatggaa ctagtaacaa aatgttcaaa
     4441 acaataggaa cgccaaacat tgctggttca tttatattaa ataatccagg tataacagtt
     4501 ataggtgcca aagtttttag ttgtttacta gctttcttct tatgtgctaa atatcctaac
     4561 gcaagaacta aacctatggt tgcaccaccg ccacctatga atacaaaatt atccataaat
     4621 acgctagtaa aaatatttgg aagagtttct ccagtttgat aagctacttt atttgcatct
     4681 agattagcta accataacgg tttcataact gcattaacaa catttcctcc gtgtaatcct
     4741 acaaaccaaa aactactatt aaggaaaatt aagataagaa gaccaataac attatttcct
     4801 aaaagtccaa gtggacctcc caaagctact tgagcaattt catgaagatt aggtaaactt
     4861 aatttatcta aagttgcata aacaatcaac caaccaacaa tagtcactgc accaggaata
     4921 atggcactaa agcttttaga tactgctggt ggaacaccat ccggcatttt tatctgtata
     4981 ttatgattta taaaccattg gtagatatag ccattaatca atcctaaaat catagcaaca
     5041 aataaacctt ttgatgccat gaaagcggta ggcattcctg ctccagcctc tcctctaatg
     5101 aaaggcgtaa ctgtaataaa agatgataat gacacaatac cagcaggaat accatcaact
     5161 ttgtattgtc tagccataaa gtaagcgata ccaaaactag ctacaagacc aagtaatcca
     5221 aaactactat caacaccctt ccataaatag tcagcaacac caatatcacc cagatatttt
     5281 tcccatcctg gaataggaaa acttgcaata accattagta atgaacctat caacaataaa
     5341 ggtatagtta gagtaatacc gtctcgaata gaaaccaacg ctttattatt acccaatcta
     5401 gccgctactg gaagtaactt ttcttgtaat aatttttcca taaccttttc ctcttaaata
     5461 tattttatta tcaaaagtta tcaattatct ttattttttg acgtcaagtt gttatttgat
     5521 tatcttttgt tatttatatt ttacaactat aagaaagcct tgtcaaggat ttgtgtaaac
     5581 atttgattat tttttattat caatatataa taaaaagaga ccagtaagta atgaaaagct
     5641 taaaaaaatt aacatctaca tttatccata gcaaaaaatc ataggatttt aagaatctga
     5701 caactaggaa gaaaactaat atgaccttat ctaagaaaca attacaacta agagctaaaa
     5761 tactggaaac agtttacaca ttaggtccca tttcacgaat tgaaatcgct actaaaacag
     5821 gaataacacc tgcaacaact agcagtatca caaatgatct gattaaagaa aatattctct
     5881 tagaacttgg tgaagacgaa cacgatacaa gcgtagggag aaaaaaaatc ctgctagaca
     5941 ttcaagctaa acgattttac tacattggtt gtgaactatc tgaaaaacat ttcacttttg
     6001 ctttaggaga taatctagga aatatcttaa aggaagagaa agaaattgtt actaaacagt
     6061 taatccaaga aaagggaaat caactcatta accagacact aaagcaattc ttaaataact
     6121 gctctgatta tgaaatagaa gcaattggaa tcgcgctacc tggtcgctat ttagataatt
     6181 ataaaataac aacaaacaat cctttatggc aacatatcga cttagaaatg attcaatccc
     6241 actttgataa gcctttgttt ttctctaaca atgttaactg tatggctata ggtaaacgcc
     6301 tatttagtcg ccaacagaat gaccctaatt ttgcttattt tcattttgct agaggtatgc
     6361 actgttctta tatctacgac ggaaacattt atgggaaagg aaatctaatg attggagaaa
     6421 tagggcatac agttgtttca tctgagggag aagaatgtag ctgcgggcgc aagggatgct
     6481 tacaaacttt tgctggagaa tcttggttaa tcaaaaaatc aaaaattcta tatcatcaat
     6541 ctccctattc tctacttcct agtttagtca aaaatgccga tgatattgat atccaagtta
     6601 ttttaaccgc ttatcaatta ggtgacactg gaataatcac acttatccat caagccttac
     6661 tctatcttag tcaaaccatt ttaaatatca gtatgatgat tgactctcaa aaaatctacc
     6721 tacatagtcc tttactaaca aatcaacaca tcatccaaaa actatatagt gaaatgaact
     6781 acaaacccaa actgctctat aatcgcctac ctgaagtcat tattgaacct tacaatgatt
     6841 ttacagccgc acactcagct attgcacttt gtttgtatca tacaattcta cattcttaat
     6901 tttctattac atttaataaa taggctaaaa agagggagta tatcataaaa agcgaataaa
     6961 cctgttttct gaaaatcaga attctgtttt gttcgctttc tttatatttg gaattatact
     7021 cctatctccc
//
LOCUS       DAVEHY010000062         6988 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVEHY010000062 DAVEHY010000000
VERSION     DAVEHY010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.062"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            127..333
                     /locus_tag="VUZ44_002068"
                     /pseudo
     CDS             127..333
                     /locus_tag="VUZ44_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            233..679
                     /locus_tag="VUZ44_002069"
     CDS             233..679
                     /locus_tag="VUZ44_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU0320918.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(817..2121)
                     /gene="eno"
                     /locus_tag="VUZ44_002070"
     CDS             complement(817..2121)
                     /gene="eno"
                     /locus_tag="VUZ44_002070"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU0320919.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2285..2731
                     /locus_tag="VUZ44_002071"
     CDS             2285..2731
                     /locus_tag="VUZ44_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU0320920.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2728..3837)
                     /locus_tag="VUZ44_002072"
     CDS             complement(2728..3837)
                     /locus_tag="VUZ44_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU0320921.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVEYLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTYGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLDLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKVSD
                     ADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAVFS
                     ILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3999..4823)
                     /locus_tag="VUZ44_002073"
                     /pseudo
     CDS             complement(3999..4823)
                     /locus_tag="VUZ44_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
     gene            complement(4813..6741)
                     /gene="glgB"
                     /locus_tag="VUZ44_002074"
     CDS             complement(4813..6741)
                     /gene="glgB"
                     /locus_tag="VUZ44_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU0320922.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         2126 a         1529 c         1229 g         2104 t
ORIGIN      
        1 gtaaaatgaa ataagaatag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt agaggtgtac tattttagtt tcaatctact atattctcaa atttcctacg
      121 cccgcgatgg acaatgcaag attccataga atgggtaagc tagaactttt atgtgaagag
      181 tttgggcata aacttttacc tcttcttccc tactcacctg agtacaatcc tattgagaaa
      241 acatgggctc atatcaaaaa gcacctcaaa aaggtattac caagttgcaa taccttttac
      301 gaggctcttt tgtcttgttc ttgtttcaat tgactatata aattgtctaa gcgaaacaac
      361 cgataagaat tggcacaaaa gcgaccgtat ttttgttacc aatacaggaa aaccagttca
      421 tagttctatc ttgagcaagt ctctccagcg agcaaacgaa cgccttaaaa aaccaattcc
      481 caaacatctg tcccctcaca tcttcagaca caccactatt agcatcttat cagaaaataa
      541 aattccttta aaaacaatca cggacagggt tggtcattcc gactctgaag tcactacttc
      601 catctacacc cacgtcacaa agaacatgaa agatgaagca atcaatgtac tggataaagt
      661 tatgaaaaag attttttaaa aagttttgcc ccttttttgt cctctaaata caaaaatagc
      721 ccttcggata aaatccgagg ggctagaaac gttgttaaat caacggccga acttttgaat
      781 ttcatggttc gggataaaat agttcactga actattttat tttttaaggt tgtagaatga
      841 tttcaatcca cgatattcag ctacttcacc aagttggtct tcgatacgaa gcaattggtt
      901 gtatttagcg atgcggtctg tacgtgaaag tgaaccagtc ttgatttgtc ctgcgttagt
      961 tgcaactgcg atatcagcga ttgttgaatc ttcagtttca cctgaacggt gtgatacaac
     1021 agcagtgtaa ccagcttctt tagccatttc gatagcttca aaagtttcag taagagtacc
     1081 gatttggtta actttgataa ggattgagtt agcagcacct tcttggatac cacgtgcaag
     1141 gtagtcagtg tttgttacga agaagtcgtc accaacaagt tgtactttct taccaagacg
     1201 ttcagtaaga gctttccaac catcccagtc gttttcatcc ataccatctt caatagtgat
     1261 gattgggtat ttgttaacca attcttcaag gtagtcgatt tgttctgcag atgtacgaac
     1321 agcagcacct tcaccttcaa atttagtgta gtcgtaaact ttacgttctt tatcgtagaa
     1381 ttctgatgaa gcacagtcaa atccaataaa tacgtcttta cctggtacat atccagcagc
     1441 ttcaatcgca gcaaggatag tttcaacacc atcttcagtt ccttcgaaac gaggagcgaa
     1501 tccaccttcg tcacctacgg cagtttccaa accacgtgat ttaaggattt tcttaagagc
     1561 gtggaagatt tcagcaccgt aacgaagggc ttctttaaat gttggcgcac caactggcaa
     1621 gatcatgaac tcttggaaag cgattggagc gtcagagtga gaaccaccgt tgatgatgtt
     1681 catcattgga gttggaagaa ctttagtgtt gaatccacca aggtagctgt aaagtgggat
     1741 ttcaaggtag tcagcagcag cacgagctac agcgatagac acaccgagga ttgcattcgc
     1801 acccaattta cctttgttag gagtaccgtc aagtgcgatc atagcacggt caatagcttg
     1861 ttgatcacgt acatcgtagc caatgatagc ttcagcaatg atgttgttta cgttgtcaac
     1921 agctttttgt gtaccaagac caccgtaacg agatttgtca ccgtcgcgaa gttcaactgc
     1981 ttcgtgttca ccagtagaag ctcctgatgg aaccatacca cgtccgaaag cacctgattc
     2041 agtgtaaact tctacttcaa gtgttgggtt accgcgtgag tctaggactt cgcgagcgta
     2101 aacatcagta ataattgaca ttttttactc tccttatgag ttaaattttt tacacctcta
     2161 taatacctta aaacccctcc tttttcaaga aaaaacgtta tctttgtgca acttttcctt
     2221 aactttataa agtaatcgct ttcttttgtc tgttttattc taacttttat gatatactgt
     2281 tttcatgaca gatttatcaa aacaattact tgaaaaagct catggtgggt taaaaataaa
     2341 tccggatgag caaagacgct atcttggtac ttttgaggaa agagttcttg gatatgtaga
     2401 tattgacaca gcaaatagcc ctcagttaga aaaaggcttt ttatttattt tagaaaacct
     2461 tcaggaaaaa gcagagccac tatttgtgaa gatttcacca actatcgaat ttgataagca
     2521 agttttctac ttaaaagaag caaaagaaac tgatagtcaa gccaccatag tatctgaaga
     2581 gcatattact tctccttttg gcctggttat tcatagcaat gcaccagttc aagtagaaga
     2641 aaaagacctt cgacttgctt ttccaaaact ttgggaagtt aaaaaggaag aaccagccaa
     2701 aacatcctta tggaagaaat ggtttagcta aatcttgcac atatttaata agtgcccaat
     2761 attggcagcc gtgcgctcca gatagagact ggcatttttc aaactatctt ctaaaggttc
     2821 acttttctcc aaaatagaaa agacagcttg gatattttca aatggtaggg gaggtaaatc
     2881 ttcagcaaga ctaccgcaaa tagcaataac aggaactcca acaggggttc tttttgcaac
     2941 acctataggc gctttcccag caaagctttg actatcaagt cttccttctc caacaacaac
     3001 caagtcagca tctgaaactt tcttatcaaa gttgattaag tccaagcagg tatcaattcc
     3061 agacacgata cttgcctgag caaaggcaca caaaccacca gcaaggcctc cacctgctcc
     3121 tttaatttct aatgttgcag gtgagaattt ttcataaaaa tcttggatcg cctgatctac
     3181 gactgcaaac atagtcggat gtagaccttt ttgattgcca aaagtgtaag tcgcaccttg
     3241 atgaccacat aagggactca cgacatctgc tagaatatga atttgaacac cttcaggaat
     3301 tttatagcaa ttttctgttg aaacagaagc taagtctaat aaggattgac cggaagcagg
     3361 caagacattt ccatccctat cataaaattg ataacctaaa ccagcagcaa tccccagtcc
     3421 tccatcatta ctggccgtgc caccaacacc gatataaata tctttaatcc ctttagaaat
     3481 gagatggaga atcaactctc caataccata agtttggatt tgaagtggat ttcgtttctc
     3541 tagcggaatt tttccaagac caaccaagtc agctacttca aatagtgcca gttccccttt
     3601 ttgaaaatag cgcatggctt ctttttgtcc aaaagggtct gtcacttgga tccatttttc
     3661 ttttaggtca agagaatgtc ggatagcatc tacagtacct tctcccccat caccaacagg
     3721 gcagaggaga tattctacat ctgctatcga ttgttggaag cctcttttta ttgcttcagc
     3781 tacctgttga gctgtcaagc tttccttaaa cgaatctggt gcaattacaa tcttcatatt
     3841 ttccctcatt ctaaacagtc aatcaaagga agaacttcta aaaaatccct cttgtcaaca
     3901 tgatgtggta tttctttttt gagcacttct ttggcacaaa aggcgattcc taactccgcc
     3961 gacttcaaca ttaatagatt attgacccca tcaccgaagt aaatcttcca ttgacggtta
     4021 cgactatcca aggcattttc tggagaaata tactccatgt tcgcttccca aagtgactca
     4081 atagtaccaa catctttcca ataaccacta aattcgtaag cataaacact ttcacctgac
     4141 tcaaggtaat ttggaatgac atttttacca aagtctgaca tgccaacctt gctcttttca
     4201 gcagcgacta acatattacg aaggcgttgc caatcaaaaa tgtagattcc catagaagct
     4261 tttgtagatt taggttgagc tggtttttct tcaaattcaa caatacgatt gttagcatct
     4321 gtgttcatga taccaaaacg gcttgcttct ttaagaggga cgtctaaaac tgctactgtc
     4381 aagctggcat tattatcctt atgagactgg agcatatcat catagtccat tttgtagatg
     4441 tggtccccag acaaaatcaa gacatactca ggattgacac tgtcgatata gtcgatattt
     4501 tggtaaatag cgtgactagt cccctcaaac caacgatttc cttcacttgc agaataaggt
     4561 tgaagaatag agacacctga attaataccg tctagtcccc agcttgaacc attcccaata
     4621 tggttgttga gagcaagtgg ttgatactgt gtaacgaccc caacattgtg aatccctgag
     4681 ttggcacagt ttgatagggc aaagtcaatg atacggtagc gcccaccaaa ttgcacagct
     4741 ggttttgcga tgctttgagt gagtttaccg agacgagttc cttgcccacc agcaagaatc
     4801 aaagctaaca tttcattttt cattttctac tcctttttgg tttttatttg tgacggtttt
     4861 agtagatttc aagcgacgtt tgattttcca tacacttgct cccatagccg gtagggtaaa
     4921 ggttaaggtc tgctcataat ctttccatag tccttcttgc gtttgaacag tttgattatg
     4981 ttctttccaa acgcctcccc actcttccaa ctcagtattc catacttctt cgtaaattcc
     5041 tgcaacgggt agtccgattg taaaatcttt ccgctcaaca ggtaccatat taaagataca
     5101 gactaacatt tctccctttt tacccttacg aataaaggaa agaacactct ggtctcgatt
     5161 atccgcatca atgatttcaa taccatcata gctggtatca atttcccaca gacagcgatg
     5221 atctttgtaa aactggttta gctgagaagc gaaatacttc atcttagcat tcattgggtc
     5281 ttctaggtta gaccattcca actgttcttc agatttccat tctaggaatt gaccgtattc
     5341 gctacccatg aagagcaatt tcttaccagg gtgacaaatt tggtacgtat agagattgcg
     5401 caagcctgca aattgattgt aacgatctcc ccacatctta tgcatcatac tcttcttgcc
     5461 atgaaccact tcatcgtgcg agaatggcaa gagataattc tccttgaaaa catacataaa
     5521 gctgaaagtc accaggttaa agtcatattt acgatagatc ggatcttctt cgtagaaacg
     5581 gaggatatca ttcatccagc ccatgttcca tttgtagtca aatcctagac caccaatctc
     5641 tttcattccc gtaatcttgg tcgcagacga actttcttct gcaatcatca tcacatctgg
     5701 atattctaac ttaataacct cattcaagcg ctgaaggaaa taataacctt catagttgag
     5761 atttccgcca tctttattag gtgtccatgg agcatcatca tagtccaaat agagcatgtt
     5821 gctaacagca tccacacgaa taccatccaa atgatagaca tcaatccaat gcttaatgca
     5881 agaaattaag aaggactgga cttcattttt tccaaggtca aaattaaggg caccccaacc
     5941 atggttatga gccttattat ggtcttggta ttcaaaagtc ggtgtcccat cataataggc
     6001 taaggcatca tcgttgatgg taaagtgacc tggtacccag tccacaataa ccccaatatt
     6061 atgggtatga cactcctcga caaaatcttg aaactcctct ggtcggccat aagcatgctc
     6121 taaagcgaag taacccataa gctgataccc ccaactcaag cccaaaggat gggacatcaa
     6181 gggcataaac tcaatatgag tatagttcat ctcaactagg taaggaatga gttcatcttt
     6241 caattgggca aaactataag gactgccatc aggatttctc ttccaagagc cagcatgaac
     6301 ctcgtaaata ttgacaggac gttcagcaaa gccccaacgt tttcttcgtg ccagccaaag
     6361 tccatccctc catttcttat caggaagctc tgttacgatt gcccctgttc ctggacgagc
     6421 ctcatacctg acagcaaaag ggtcaatctt catcagttga tgaccatttt gacgtgtgac
     6481 atgatatttg taaatatgcc cttcttgagc catattggta aagacttccc agaccccaaa
     6541 gtcatttctt accattggaa tctgattttc aatccaattg gtaaaatcac caaccaagtg
     6601 aacagcctga gcattaggtg cccaaacacg gaaggtatag ccatactctc catttagttc
     6661 ttccctatgt gctcctagat aatgttggag ataaaaattt tcacccgtca taaaggtttt
     6721 taatgcttct ctattatcca tatactccct ttctcatgta agcgttttct atgtttttat
     6781 tatactacct ttttagagaa gattcaagta aattactata cttctttaat tattttgaaa
     6841 atctacaaca agttcactta ctcgttcaat tgtaaatcaa tattttttca aaaaattgcg
     6901 aaaacacctt tctttttcta ctatagtgaa atgaaataaa acatgcgcaa atcgattaag
     6961 gaatttaatc taatttctaa caatgtct
//
LOCUS       DAVEHY010000063         6240 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVEHY010000063 DAVEHY010000000
VERSION     DAVEHY010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6240
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.063"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(58..1791)
                     /gene="ptsP"
                     /locus_tag="VUZ44_002075"
     CDS             complement(58..1791)
                     /gene="ptsP"
                     /locus_tag="VUZ44_002075"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU0320923.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(1797..2060)
                     /locus_tag="VUZ44_002076"
     CDS             complement(1797..2060)
                     /locus_tag="VUZ44_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU0320924.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            2411..2629
                     /gene="nrdH"
                     /locus_tag="VUZ44_002077"
     CDS             2411..2629
                     /gene="nrdH"
                     /locus_tag="VUZ44_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU0320925.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            2710..4869
                     /gene="nrdE"
                     /locus_tag="VUZ44_002078"
     CDS             2710..4869
                     /gene="nrdE"
                     /locus_tag="VUZ44_002078"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU0320926.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            5057..6019
                     /gene="nrdF"
                     /locus_tag="VUZ44_002079"
     CDS             5057..6019
                     /gene="nrdF"
                     /locus_tag="VUZ44_002079"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU0320927.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
BASE COUNT         1850 a         1342 c         1164 g         1884 t
ORIGIN      
        1 aaattctttt taaaatatca aaaaaatccc tgtaactgag ttgcagggac ttttcgatta
       61 atcaaaatta acgtattctt tttgaagttc aagaacttct tccattgttg agcattctgt
      121 aagggcacgg tttgcgtact cttccatctt agctgtgtcg agtttcttca tcaagctgcg
      181 tgtacgaagt acagatgttg ctgacataga gaactcatcc aagcccattc cgacaagaag
      241 aggaacagct tgttggtcac cagccatctc accacacata ccagcccatt taccttcagc
      301 gtgagctgct ttgatcacat tgttaatcaa gcgtaggatt gatgggttgt atggttggta
      361 aaggtatgaa acttgttcgt tcatacggtc tgctgccatt gtatattgga tcaagtcgtt
      421 tgtaccaatt gagaagaagt caacttcttt agcaaattgg tctgcaagca tagccgctgc
      481 aggaatctcg atcatgatac caacttggat gttatccgca actgcaacac cttcagcaag
      541 aaggtttgct ttttcttcat caaagactgc tttcgctgca cggaattctt tcaagagcgc
      601 aaccattggg aacatgatac gcaattgacc gtgaacagac gcacgaagaa gagcacggat
      661 ttgtgtgcgg aacatagcat ctccagtctc agagatagag atacgaagag cacggaatcc
      721 aaggaatggg ttcatttcgt gaggcatatc gaagtaagga agttccttat ctccaccgat
      781 atccattgta cgaacgacaa caggtttacc gttcattcct tcaagaacag ccttgtatgc
      841 ttcatactgc tcatcttcag ttgggaagtc ttgagaatcc atgtacaaga actctgtacg
      901 gtaaagtcca acagcttctg caccgttgtt gttaacacct tcaacgtctt ttggagtacc
      961 aatattggca gccaactcga agtgtttacc gtcagcagtc actgtttgag catctttcaa
     1021 aagtgcccat tcagcttttt gtttcgcata ggcttcacca gctgctttaa attctgccgc
     1081 ttgttcatct gttgggttga taatcacttc tccagtgatc ccgttaacag caaggatgtc
     1141 accgtcttta acgatttcag tgatgttgtt tgtacctaat acagcagcaa tttcaagtgt
     1201 acgtgccatg atagctgagt ggcttgtacg tccaccgatg ttggttacaa aagcttttac
     1261 aaagtttttg tccaattgag ctgtatcaga tggtgtcaag tcatgtgcaa tcacaatcac
     1321 ttcttcattg atagaagctg ggtttggcaa ttttttacca agaaggtttg ccaatacacg
     1381 ttttgtcacg tcgcggatat ccgctgcgcg ttcttgcatg tatgggttgt cttccatgcc
     1441 ttcaaagata gtgataaaca tatctgtaac ttctttcaga cctgcttctg cattcacttt
     1501 cttcgcacgg atagtttcct tgatttggct gatcatttct gggtcagcaa gaaccattaa
     1561 gtgagcatca aaaacttgag ctgcttcttc accgagcgta cctactgctt tctcgcgaat
     1621 aacagaaagc tcgtcttgtg atgcctgtag agcggcatca aggcgagctt cttctgcgtt
     1681 tgtatcttcg actgtaatag tctcaaatga caaatccggc tgaacgagta gatatgcttt
     1741 tgcaactgca acaccgtcag atgctgcgat tcctttaagc atttctgtca tttcccttat
     1801 gccaatcctt ctttttccat tgtttctgag attgcagcga tagcgtcatc tgcatctgca
     1861 ccttcagctg agatagttac gtcagcacct tgaccaacac caagactcat aacacccata
     1921 attgatttaa ggttaactga tttacctttg tactcaagag tgatatctga agcaaatttg
     1981 ctagcagttt gtaccaacaa tgttgctgga cgtgcgtgaa tacctgtttc tgccactacg
     2041 tggaaatctt tagaagccat agtttgactc tccttttgtt ctttcttttt ttgagttata
     2101 tgtgataacc cttacaattt agtattatac catcttctag gatttttttc aagcattttc
     2161 tggattttcc ttcaatttcc tttcagataa cttgctgaaa atcttctatc ctagataaca
     2221 aaacacagga tatagtttct tcaaaaacaa tttataggat aatcattgct atttcacaat
     2281 acaaacacta tatattgtgt ttatatatga aaacaacaaa agaacaccac tatatttagt
     2341 ttaaatcatt gacaaaattt tattttctga tatactaaga tagtattaaa ttttgaagag
     2401 gagttacaca atggtaaccg tttattctaa aaacaattgt gtccaatgta aaatgaccaa
     2461 gcgtttcttg gacagtaata atgtctctta tcgtgaaatc aatcttgatg agcaacctga
     2521 gtacgtcgat caagttaaag agctcggttt tagcgcagct cctgttatcc aaacaccaac
     2581 tgaagtcttt tcaggtttcc aaccaggaaa actgaaacaa ttagcataat cttagtacat
     2641 catccagaag aaactgcttt tagggctaac ttagaagcct ttcttttgta attagataag
     2701 ggaaatttta tgggattaaa acatcttgaa gacgtgactt acttccgtct taataacgaa
     2761 attaaccgtc ctgttaatgg acaaatcatg cttcataaag acaaggaagc cttggatgct
     2821 ttctttaaag aaaatgtagt tccaaacact atggtttttg attcaatcaa agacaaaatc
     2881 aattacctca ttgaacacaa ctacatcgaa acagccttta tcaagaaata ccgtccagag
     2941 ttcttggaag aattagctca atttatcaaa gaccaaaact tccaattcaa gtcattcatg
     3001 gcagcttata aattttacaa tcaatatgcc ttaaagacta atgacggtga atactatctt
     3061 gaaaatatgg aagaccgtgt cttcttcaac gccctttatt tcgctgatgg gaatgaagct
     3121 gttgcaatcg atattgccaa tgaaatcatc caccaacgct accaacctgc tactccttcc
     3181 ttcttgaatg ctggacgtgc tcgccgtgga gagttggtat cttgtttcct aatccaagtg
     3241 acggatgata tgaactctat cggacgttct atcaactcag ctcttcaact ttcacgtatt
     3301 ggtggtggtg tgggaattac cctcagcaac cttcgtgaag ctggtgcacc tatcaaaggc
     3361 tatgaaggag ctgcttcagg tgtcgttcct gttatgaagc tttttgaaga cagcttctct
     3421 tactccaacc aattggggca acgtcaaggt gccggtgttg tctacctcaa cgtctttcac
     3481 ccagatatca tcgctttcct ttcaactaag aaagaaaacg ctgatgaaaa agtacgtgtc
     3541 aagactctat cacttggtgt tgtagtacct gataaattct acgaattggc tcgtaaaaat
     3601 gaagaaatgt acctcttcag cccttactct gtagaaaaag aatacggtgt gccattcaat
     3661 tacatcgaca ttactgaaaa atacgatgaa ttggtcgcaa atccaaatat tcgcaagaca
     3721 aaaatcaagg cgcgggattt ggaaactgaa atctctaaat tgcaacaaga gtctggctat
     3781 ccttatgtag tcaacatcga tacggctaac cgtgcaaatc ctgttgatgg aaagattatc
     3841 atgagtaact tgtgttctga gattcttcaa gttcaagaac caagcttgat caacgatgct
     3901 caagaattcc ttcaaatggg aacagatgtt tcatgtaacc tgggttcaac caacgtggtt
     3961 aacatgatga cttcacctga ttttggtcgt tctatccgtg ctatggttcg tgcccttact
     4021 ttcgttacag atagttcaca tatcgtagct gtaccaacga ttgaccatgg aaatagccaa
     4081 gcccacacct ttggtctcgg tgccatggga ctgcacagct accttgccca acaactcatt
     4141 gaatatggtt cacctgagtc tgttgaattt acaagcatct actttatgct tatgaactac
     4201 tggaccttgg tagagtcaaa caatattgcg cgtgaacgtg gtattacctt ccacaacttt
     4261 gaaaaatcag actatgctaa cggaagttac tttgacaagt atgtaactgg tgaatttgtt
     4321 ccaacatcag accgtgttaa agaactcttc aaaaatgtct ttatccctgg tgttgctgat
     4381 tgggctgaac ttcgcgacaa ggttcaagaa gatggtcttt accaccaaaa tcgccttgct
     4441 gtagcgccaa atggttctat cagctatatc aacgacgttt ctgcttctat ccacccgatt
     4501 acgcaacgta tcgaagaacg ccaagagaag aaaattggta aaatctacta ccctgctgct
     4561 ggcttgtcta cagaaaccat tccttactac acttctgcct acgatatgga tatgcgtaaa
     4621 gtcatcgatg tttacgctgc tgcgactgaa cacgtggatc aaggactttc actcaccctc
     4681 ttcatgcgta gtgacattcc aaaaggcctt tacgaatgga agagggaaaa taaacaaacg
     4741 acacgtgact tgtccatcct tcgtaactat gcctttaaca agggaatcaa gtctatctac
     4801 tacgtccgta cctttacaga tgacggtgga gaagtcggcg ccaaccaatg tgaaagctgt
     4861 gtgatttagt ttctagcata gaaacattat ttttccctaa gcagcactga taaaatcaaa
     4921 tctactatgt cataacataa tttatgtaac attttaaaag tcgggcttcc gactttttgt
     4981 gcgatactcc tatagaatta tggtaaagta gaaataattg tgagttcgca atactaaaca
     5041 cagaaagaga ttttaaatgg aaacttacta caaagccatt aactggaatg ccatcgaaga
     5101 tgtcatcgac aaatcaactt gggaaaaact gacggagcaa ttttggctcg atacacgtat
     5161 tcccttatca aacgacttgg atgactggag aaagctatct aacaaagaga aagacttggt
     5221 cggaaaagtt tttggtggtt taacccttct tgacactatg caatctgaaa ctggggttca
     5281 agcccttcgc gcagacatcc gtacaccaca tgaggaagct gttttcaata acatccaatt
     5341 tatggaatct gtccacgcta aatcttactc atcaatcttt tctaccttga atactaaggc
     5401 tgagattgaa gaaattttcg aatggaccaa taccaatcct tacctacaaa agaaggctga
     5461 gattgtcaac gaaatctacc taaacggcag cccacttgaa aagaaagttg ccagcgtctt
     5521 cctcgaaacc ttcctcttct actctggttt cttcactccc ctctactatc tcggtaacaa
     5581 caaactagcc aacgttgcag aaatcattaa attgattatt cgtgacgagt ctgttcacgg
     5641 aacctacatt ggttacaaat tccaacttgg tttcaatgaa ttgcctgaag aagagcaaga
     5701 aaaactcaaa gaatggatgt acgacctact ctatactctt tatgaaaatg aagaaggcta
     5761 cacagagagt ctttatgacg gtgttggttg gactgaagag gttaaaacct tccttcgcta
     5821 caatgccaat aaagctctca tgaacatggg acaagatcca cttttcccag attcagctga
     5881 agatgtcaac ccaatcgtta tgaacggtat ttcaacagga acttccaacc atgacttctt
     5941 ctctcaagtc ggaaatggtt accttcttgg cgaagttgaa gccatgcaag atgatgacta
     6001 caactacggt ttggactaat actcttcgaa aatcaaattc aaaccacgtc agcttcgcct
     6061 tgccgtactc aagtacagcc tgcggctagc ttcctagttt gctctttgat tttcattgag
     6121 tataattctc caccactctt aaccatcaaa aagtaaacta gaaacaacaa aataataact
     6181 taataaaaat atcgaaagtt ttgaaaataa acctcgatat ttttgttttt gttttatttt
//
LOCUS       DAVEHY010000064         6202 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVEHY010000064 DAVEHY010000000
VERSION     DAVEHY010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6202
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.064"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            1..124
                     /locus_tag="VUZ44_002080"
                     /pseudo
     CDS             1..124
                     /locus_tag="VUZ44_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            279..479
                     /locus_tag="VUZ44_002081"
     CDS             279..479
                     /locus_tag="VUZ44_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320928.1"
                     /translation="MVVSASASSTSPQAQEQVDKSELRALSQELDQHLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            504..920
                     /locus_tag="VUZ44_002082"
     CDS             504..920
                     /locus_tag="VUZ44_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320929.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1151..1858
                     /gene="ccdA2"
                     /locus_tag="VUZ44_002083"
     CDS             1151..1858
                     /gene="ccdA2"
                     /locus_tag="VUZ44_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU0320930.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1869..2426
                     /gene="sdbB"
                     /locus_tag="VUZ44_002084"
     CDS             1869..2426
                     /gene="sdbB"
                     /locus_tag="VUZ44_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU0320931.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2801..4192
                     /locus_tag="VUZ44_002085"
     CDS             2801..4192
                     /locus_tag="VUZ44_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU0320932.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4335..5252
                     /gene="adcAII"
                     /locus_tag="VUZ44_002086"
     CDS             4335..5252
                     /gene="adcAII"
                     /locus_tag="VUZ44_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU0320933.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLDRVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5260..>6202
                     /gene="phtB"
                     /locus_tag="VUZ44_002087"
     CDS             5260..>6202
                     /gene="phtB"
                     /locus_tag="VUZ44_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU0320934.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     NQAGQKAENLTPDEVSKREGISAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPH"
BASE COUNT         1891 a         1134 c         1316 g         1861 t
ORIGIN      
        1 tgaattaatc gctccaatga cttacgaaga gacgatgacg agcgactttt ttgaagcttg
       61 gtttcagaag tttctcttac caacattaac cacaccatcg gttattatat taaaacgaaa
      121 taagaatagg acaaatcgat caggacagta aaatcgaatt ctaacaatgt tttagaagtc
      181 catatgtact attctagttt caatatacca taactgctcc tagtcaacct gcaagtcctg
      241 tcccagctcc aagctcagct ccgactcaag atcctagagt ggtagtaagc gcttcggcta
      301 gctcaacgag cccacaagct caagagcaag ttgacaagtc tgaacttcgt gccttgagtc
      361 aagagttaga ccaacacttg aaagctttgg caacagtatc tgatccgaaa atcgatgcaa
      421 ccaaggctgt cctcctagat gctcaaaaag ctccggaaga tagtgccttg acagagtaag
      481 gtctgcatac tgcagtagag tctgtgaagg ctgccttgga ctctctcaaa gatgtgaaag
      541 caaatgctag cgacagcaag cctgcacagg acaagaagga tgcaaaacaa ggaacggaag
      601 atagtaagga ttcagataag atgactgaaa caaactcagt tccggcagga gtgattgtgg
      661 tcagtctact tgccctccta ggcgtgattg ccttctggct gattcgccgt aagaaagagt
      721 cagaaatcca gcaattaagc acggaattaa tcaaggttct aggacagcta gatgcagaaa
      781 aagcggataa aaaagtcctt gccaaagccc aaaaccttct ccaagaaacc cttgatttcg
      841 tgaaagaaga aaatggctca gcagagacag aaactaaact agtagaggag cttaaagcaa
      901 tccttgacaa actcaagtaa aacatgattt atgaaatgtc agacttaaaa gacattttcg
      961 ttcacaaaag cagcgacgag taatccttgt cgttgctttt tggctatttt gggggataag
     1021 atccgccttg actagcaaaa gaaaagattg gtccaatagt gcccgatacg attttgcgta
     1081 gcagaaagct tacaaataaa attgaatata gtaaaatagg attagaatta ttaagaaagt
     1141 tggttcttta ttggaaacga tagtattttt aatctctgtt tttctagcag gtgttttatc
     1201 ctttttttct ccttgtattt ttcctcttct gccagtctat gctgggattt tattggatga
     1261 tcaagaaagt gcaaaaagct tttctttgtt tgggagaaag gttctctggt caggcttgat
     1321 tcgaacactt tgctttatcg ctggtatctc tctcattttc tttattctag gctttggtgc
     1381 tggttacttt ggtcatattc tctatgcaaa ttggtttcga tatggcatgg gagctattat
     1441 tatcattttg ggtcttcacc agatggaaat ttttcatttg aagaaattag aagttcaaaa
     1501 aagttttacc tttaaaaaat cagattctaa tcgttattgg tcagcttttt tacttggtat
     1561 tacctttagc tttggttgga caccttgtat tggtccagtt ttaagttctg ttttagcact
     1621 tgcggcttct ggaggcaatg gcgcttggca aggagcgatt tatactctca tttacactct
     1681 gggcatggcc cttcctttct tggtattggc actagcttca ggtctagtca tgccatattt
     1741 tagtaaaatc aagcgtcata tgatgctact aaagaaaatt ggtggtttcc tcattgtttt
     1801 aatgggaatt ttgttactat taggacaagt aaatgttcta gctggaattt ttgaataaag
     1861 gaggacaaat gaaaaaagta atgtttgctg gcttaagtct cttgtcatta gttgtattga
     1921 tggcctgtgg tgaggaagaa actaaaaaga ctcaagcagc acaacagcca aaacaacaaa
     1981 cgactgtaca acaaattgct gttggaaaag atgctccaga ctttacattg caatccatgg
     2041 atggcaaaga agttaagtta tctgatttta agggtaaaaa ggtttacttg aagttttggg
     2101 cttcatggtg tggtccatgc aagaaaagta tgccagagtt gatggaacta gcggcgaaac
     2161 cagatcgtga tttcgaaatt cttactgtca ttgcaccagg aattcaaggt gaaaaaactg
     2221 ttgagcaatt cccacaatgg ttccaggaac aaggatataa ggatatccca gttctttatg
     2281 ataccaaagc aaccaccttc caagcttatc aaattcgaag cattcctaca gaatatttaa
     2341 ttgatagcca aggaaagatt ggaaagattc aatttggtgc tatcagtaat gcggatgcag
     2401 aagcagcatt taaagaaatg aactagaatc gataaaatct gattacaaga tgtagtcaga
     2461 ttttggtaac ttctaaaact aacttccagt ttcccacaac ctagctttta gtatgagaaa
     2521 aacgcgtgac atcagtggaa atccgtctta gactaacttc cactggtttt ctttttcttg
     2581 atatataagg gttcaaaagc gaaaagactc agaaaaaagt gcacgacaaa tagccctaaa
     2641 acagagtcgt tttagagtaa cttccagttt tgggagagag atggaagtta ctttgagaag
     2701 ttacggtagt cagatttttt tagaaaaaca ttttataaat attcacatat ctcctatatt
     2761 tatggtaaaa tagaatcatc agtttatttt ggagtcaaag atgaatatat ttagaacaaa
     2821 gaatgttagt ttagataaaa cagagatgca taggcatttg aagttatggg atttgatttt
     2881 gctgggtatc ggagccatgg tagggacagg cgtctttaca atcacaggta ctgcagctgc
     2941 aacacttgct ggcccagccc tagtgatttc aatcgttatt tctgccttgt gtgtgggatt
     3001 atcagccctc ttttttgcag aatttgcctc gcgagtaccc gctacaggag gtgcctatag
     3061 ttacctctat gctatcttag gagaattccc tgcctggttg gctggttggt taaccatgat
     3121 ggagttcatg acagccatat caggcgtagc ttcgggttgg gcagcttatt ttaaaggctt
     3181 gctctctcaa tatgggatag cccttcctca ggctttaaat ggtaccttta atcctcaagc
     3241 agggacattt gttgatttat tgcctattct tgtcttggtc ttggtgactt cgcttgtttt
     3301 actaaatgcc aaggcagcct tacgctttaa ttcgattcta gttattttga aattttccgc
     3361 tttagctctc tttgttttag taggaatttg gaatattaag tttgataatt ggagcaattt
     3421 tgctccttac ggctttggac aaatctatgg agctagtact ggtattatgg ctggtgcgtc
     3481 cttgatgttc ttcggttttt tgggatttga atccatctct atggctgtag atgaagtcaa
     3541 gactcctcaa aaaaatattc ctagagggat tgtcttatcg ctttctatcg taaccattct
     3601 ctatgccttg gtgacccttg ttttgactgg tgtggttcac tatagtcatt taaatgtcga
     3661 tgatgccgtt gcctttgccc ttcgtagtgt tgggattagt tgggcagcca actatgtgtc
     3721 attagtggct atcttgacct tgattacagt ttgtatttcg atgacctatg ccctatcgcg
     3781 tatgatttac agtttagcac gtgacggctt agtgcctgct gcctttaagg aactgacgaa
     3841 gactagcaag gtaccaaaga atgctactat cttgacaggt ctagcttcag cagtagcagc
     3901 aggaatgttc ccactagcca gtattgcagc ctttttaaat atttgtacct tagcctactt
     3961 gatcatgctg gcttatggtc tgattcgctt acggaaagaa aaaggaatgc ccaaagctgg
     4021 ggaatttaaa acaccattgg tacctctgtt accaatttta tcgatcatca tttgtttatc
     4081 cttcatgtta cagtataata tgaacacctg gattgctttc ctagttgcgt tgttagtagg
     4141 aagtattatt tacttcactt atggctataa gcattctacc atagaagaat aaagtgaaag
     4201 tctattgagt tgttgacact cagcagattt ttatatgtga aagaaatttc aaattttttc
     4261 taaaaatatc ttgacagatt aaattttcag gagtagaata tttactagtt aattaaatgg
     4321 ttaaggagtt gttcatgaag aaacaaaatt tatttttagt cctgttaagt gtctttcttt
     4381 tgtgcttggg ggcttgtggt caaaaggaaa gtcagacagg aaaggggatg aaaattgtga
     4441 ccagttttta tcctatctac gctatggtta aggaagtatc tggtgacttg aatgatgttc
     4501 ggatgattca gtcaagtagt gggattcact cctttgaacc ttcggcaaat gacatcgcgg
     4561 ccatctatga tgcagatgtc tttgtttacc attctcatac gctagaatct tgggcaggaa
     4621 gtttagatcc caatctaaaa aaatctaaag tgaaggtttt agaggcttca gagggaatga
     4681 ctttagaccg cgtcccagga ctagaggatg tggaagcagg ggatggagtt gatgaaaaaa
     4741 cgctctatga ccctcacact tggctagatc ctgaaaaagc tggagaagaa gcccaaatta
     4801 tcgctgataa actttcagag gtggatagtg agcataaaga gacttatcaa aaaaatgcgc
     4861 aagcctttat caaaaaagct caggaattga ctaagaaatt ccaaccaaaa tttgaaaaag
     4921 cgactcagaa aacatttgta acacaacata cagccttttc ttatctagcg aagagatttg
     4981 ggcttaatca acttggtatt gcaggtatct ctcctgaaca agaaccaagt ccacgacaac
     5041 taacagaaat tcaggaattt gttaagacct ataaggttaa aacgattttt acagaaagta
     5101 acgcttcttc aaaagtagct gaaactcttg tcaaatcaac aggtgtgggt cttaaaactc
     5161 tgaatccttt agagtcagac ccacaaaatg acaagaccta tttagaaaat cttgaagaaa
     5221 atatgagtat tctagcagaa gaattaaagt gaggaaagaa tgaaaatcaa taaaaaatat
     5281 ctagcaggtt cagtggcagt ccttgcccta agtgtttgtt cctatgaact tggtcgtcac
     5341 caagctggtc aggttaagaa agagtctaat cgagtttctt atatagatgg taatcaggct
     5401 ggtcaaaagg cagaaaattt gacaccagat gaagtcagta agagggaggg gatcagcgcc
     5461 gaacaaatcg tcatcaagat tacggatcaa ggttatgtga cctctcatgg agaccattat
     5521 cattactata atggcaaggt cccttatgat gccatcatca gtgaagagct cctcatgaaa
     5581 gatccgaatt atcagttgaa ggattcagac attgtcaatg aaatcaaggg tggttatgtc
     5641 attaaggtaa acggtaaata ctatgtttac cttaaggatg cggcccatgc ggacaatatt
     5701 cggacaaaag aagagattaa acgtcagaag caggaacgca gtcataatca caactcaaga
     5761 gcagataatg ctgttgctgc agccagagcc caaggacgtt atacaacgga tgatgggtat
     5821 atcttcaatg catctgatat cattgaagat acgggcgatg cctatatcgt tcctcacggc
     5881 gaccattacc attacattcc taagaatgag ttatcagcta gcgagttagc tgctgcagaa
     5941 gcctattgga atgggaagca gggatctcgt ccttcttcaa gttctagtta taatgcaaat
     6001 acagctcaac caagattgtc agagaaccac aatctgactg tcactccaac ttatcatcaa
     6061 aatcaagggg aaaacatttc aagcctttta cgtgaattgt atgctaaacc cttatcagaa
     6121 cgccatgtgg aatctgatgg ccttattttc gacccagcgc aaatcacaag tcgaaccgcc
     6181 agaggtgtag ctgtccctca tg
//
LOCUS       DAVEHY010000065         6043 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVEHY010000065 DAVEHY010000000
VERSION     DAVEHY010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.065"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(1..447)
                     /locus_tag="VUZ44_002088"
                     /pseudo
     CDS             complement(1..447)
                     /locus_tag="VUZ44_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(827..1687)
                     /locus_tag="VUZ44_002089"
     CDS             complement(827..1687)
                     /locus_tag="VUZ44_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU0320935.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1703..2980)
                     /locus_tag="VUZ44_002090"
     CDS             complement(1703..2980)
                     /locus_tag="VUZ44_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU0320936.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2973..3524)
                     /locus_tag="VUZ44_002091"
     CDS             complement(2973..3524)
                     /locus_tag="VUZ44_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU0320937.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3540..4799)
                     /locus_tag="VUZ44_002092"
     CDS             complement(3540..4799)
                     /locus_tag="VUZ44_002092"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU0320938.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGERDLRGASIKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         1843 a         1348 c          984 g         1868 t
ORIGIN      
        1 ccttgacttg tgacaatcgc ttgagccttc atagcgtgaa atttcttttt accagaataa
       61 ttcgctaatt ctttttttag ggcgattggt ttttacttcc gtcgcatcaa tcattaccgt
      121 gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacca ctttgaacaa gagttacttc
      181 aacccattgg ctccgacgga ttaagttgct ttcgtgaata ccaagatcag ccgcaatttg
      241 ttcataagtt cgatattctc gcacatattg aagagtggcc ataagaaggt cttctaggct
      301 taatttaggt tttcgtccac cttttgcatg tttaagttga taagctgttt ttaatacagc
      361 taacatctct tcaaaagtgg tacgctgaac atcaacaaga cgcttaaatc gtgcatcagt
      421 tagttgttta cttgcttcat cattcataga actactatac catgttttgt ttcgcaggaa
      481 gtataatata aaaaaataaa tttaagattg gcaatacgaa cgttaaacag aattccattt
      541 ctctttttag aatcaaaacg acaatattgt gaaatctcta caggaacaat agactgcgac
      601 actaaaatat cctcccttag ttttacttta ctaatagtat ataggaggag agccctgaat
      661 cctagaccct ttgttatgat gcgcttacaa acagagttgg aaaaaatctt aaaagcagaa
      721 aaacgcatga tatcagcccc taacacttga tacaatacgt tttattatga aaagatctac
      781 tggatttttt atcaaaataa acttccagta gtcttttcac tttttattaa taagttcctt
      841 cttcaccttg gctagtcaag ataacaggtc catctttcgt aatgacaaat tggtgttcat
      901 actgacatga caatccaccg tcaatggtct tatgcgccca accagttttc atatctgtat
      961 caatttccca atcgcctgta ttgatcattg gttcaatggt taagaccatt ccttcacgaa
     1021 gacggagtcc acgacctgca ataccatagt taggaaccat tggttcttcg tgcatagttg
     1081 ggccaacacc atgaccaacc aaatcacgca ctacaccgta accacgactt tcagcgtatt
     1141 cttgaatagc cgcaccgata tcaccgatac gatttccaac aacagcttgc tcaataccct
     1201 tgtacatagc ttctttggtt acatccatca agtttttgac ttcttcggac ggtgtaccaa
     1261 cagcataagc ccaacatgag tctgctaaac caccagaata gctctgagta tattttttca
     1321 tttgttcaac attgttgaag tttaattttg agacattcag gtcagattta gcaatgggac
     1381 ctcccaaaac catatcaact ttgagcaaat caccatcttt caagatataa tgacgaggga
     1441 aagcgtgagc cacttcatcg ttaagagagc aacaggtagc ataaggatag tccatcatgg
     1501 caccgtcaac cccaatctga agtggaagga aattttcttc tttacaacga cggcggacat
     1561 attcttcaac ttcccacata tctacgcctg gcttaatcaa atcacgtaag cctatatgaa
     1621 tacttgctag aaaatcacca gccttgtcca tagcttcgat ttcacgagct gattttaatg
     1681 ttatcatctt ttctcctagt ttctaattaa ttttaacagt cacatttgct tttgaaacaa
     1741 tctggtgacc atgataaata tcgtaatcaa ttatagctga ccgtctcgta tgatgaataa
     1801 tccgtgcctg aatgcgcaat atatcatcta tctgaacagc ctgcaaaaag tagatcagca
     1861 tctgctcgat aatgagattg cgaccactat taacaactaa atcttgggtc atgtgggtca
     1921 gaatttctgc caatacacca ttagccaaaa ctccattttt ttctagcata aagggttcca
     1981 ctgtaatgac tacttcatca tggtgataag agagcttttg tccaatctgc tcagaaaaag
     2041 ttggtagagc cgaaacttgg gaacggctca tcttctccat gacatctcgt cgcgtcacaa
     2101 cgccaagcaa agtttgattg cttcgaacaa ctggtaccat ttcaaagtct tctgcgatca
     2161 tccgttgact cacattggca atatttgtcg ataatccaac caaaaataga ctacgagaca
     2221 taaccttatc aattgtcgtg cttggtgatt tatcaccagc gtctctcatg gttacaacgc
     2281 caacaacgac ctgatgttga ttgataacag ggaaacggct gctacgattc ttacgaacca
     2341 agtccaaata atctttaact gtatctgtct ctctcagaaa accatactca tgactagggc
     2401 gataaagttt ctcaactgtc agaatatcag tcttgatttg gacatttgac aaggctttat
     2461 tgatcatggt cgcgacggta aaggtatcat gcttacttct tagaacagga atcccttttt
     2521 gattggccag tttaagcaca tcatcatgaa cctgaaatcc ccctgtaacc agaactgcat
     2581 tttcattttc caaggctagc aactgaatac gggttcggtc tccgacaatc aagagccccc
     2641 catcatgaag gtaagacaag atattttgtt cagtcatggc accaattgaa aacttactaa
     2701 attctctctc taaaccttct tgcccagcca gaacctcaga agaagtcact tctgcaattt
     2761 cagcaaacgt taatctctct atagcaactt tctgggattt aacacgaatt gttccacttc
     2821 taggacgggt ctccacaatt ccacggtttt cagcttcttt aatagcccga taggctgttc
     2881 catcactaac tcctagatga ttcgaaatgc tacgaacact gaccctttta cctactggta
     2941 attcctccaa atagcttaga atttcctgat gcttactcat tgaactctcc ttttacatac
     3001 cgaaattcaa gataatcccg catttttctt gtgtaacgat cacttccctt aaactgacgg
     3061 aacaaactaa atccagactt aagagcaact ctttggctag cttcattttc aaggtgggta
     3121 atgatagata attgttttaa gccaaattcc tcaaaagaaa gctgacaaat ttttctaaca
     3181 acctctgtca taaatccttg cgaccaagca tcttttctca aaaaatagcc aagctcagct
     3241 tcttttttga tttcatctaa cttctcaaat ttaatagaac caatcatttg ttgatttttc
     3301 tggtcacaaa ttgcccacac tcccaaaggg gacttcataa agtaattggc cagtgcatat
     3361 tgactttctt ccagacttgc ctgcgttggg aaaataaatt gaagattttc tggatttgaa
     3421 gctatctcgc ggaagtcctg actatcacta aaaaagaaag gacgcaaata caagcgatcc
     3481 gtttcaaaaa aagaaaacat tgctaatttg gtccaaatat tcataaacat ctctacggtt
     3541 taatcctcaa caagtctaat atccgctcct aaattacgta atttttcgat aatatcagaa
     3601 taaccacgta agataaactc gatattggta atttcagttt taccttcagc cataagccca
     3661 gcaatgacta gtgcagcccc agctcttaag tcggtcgctt taatactggc cccacgtaaa
     3721 tcacgttcac ccgtgtacaa aatatgacca tttgttgtcg aaatatccgc atccatcttt
     3781 gctagttcaa aaacatgatt tacacgtttt tcgtaaatcg tatcgacaat tgtaccacga
     3841 ccattcgctc ttagtaaaag aggggtaagc ggttgttgca aatcagttgc aaagcctggg
     3901 taaggagctg tcttaatatt gattgctttc aaattagact gttcctcgac aaaaatgctg
     3961 tcttcagata cagtcattct cactcccatt tcttccaact tagcaataaa cccttccagg
     4021 tgttcgtaaa gaacattatt tatacgaatt cctttaccaa ctgcagcagc taaagatata
     4081 tatgttccag cttcaatgcg gtctggaatc acctgatgac gtgtcccatg taatctttca
     4141 acaccatcaa taatgatgat attagttcct gccccacgga tatgggcacc catattattc
     4201 aagagagtag ctacatcaat aatctcaggt tcacgggctg cattttcaat aatagtacga
     4261 ccatttgctt taaccgcagc aatcatcgta ttaatcgttg ctcccacact aaccgtatcc
     4321 atgtaaatac ttgcaccatg aagtcctgta tctttagcag ataacttcat gttatctccc
     4381 tcgtagctag cagtggcacc catagcttca aacgccttaa ggtgtaagtc aatcggacga
     4441 ggaccaagat cacatcctcc cggtagacca actgtcgctt caccaaaacg gcctaagagg
     4501 ctcccataaa aatagtaaga tgcacgaaga ctgttaattt taccataagg cattggaata
     4561 ttttgaacac ctcttggatc aatctccaag acatcgtcat aacgcttaac agtagctccc
     4621 attaattcca tgatttcgac aagactggct acatccgaaa tatctggaac acaatccaaa
     4681 gtcaccacat catcagccaa tataatagct ggaattaagg ccacaacact atttttagca
     4741 ccactaatag taatttcacc ttgcagtggt aatccaccat tgataacaat ttttctcatt
     4801 ctaagttttc aatactcttt caagatttct aataaggtct tcaaaataaa gtatatcata
     4861 aatttatcct tttttccatc cttttcaatt ttattggata aatcagagtt gacgagttag
     4921 taactgaatt actaatactc aatgaaaatc aaagatcaaa ctaggaaact agccgcaggt
     4981 tgctcaaaac actgttttga ggttgtagat ggaactgacg tagtcagtat cctacacata
     5041 cggcaaggcg atattgacgt gatttgaaga gattttcgaa gagtataatc tttctcgaat
     5101 cgctattgcc ccttttttat cccctaaaac tgagtaggat ctaagactag atctcttatc
     5161 taagtatcgg aatacggctg ttcaactaaa ttttagcaag aacttctccc cttctctcag
     5221 ttcacagaag cgttttatac ataccgtcct atcagacaat ctattttaaa gataaccgtg
     5281 actcaggatc acttctatct gtcgttttct ctttatagtg atagacctca cgggataagt
     5341 cgtacatctt tcctcgtgta tacaagatat aaggacgtta aaaggttaca gtgaaaatag
     5401 aaaatcttag tacgaattca attactctcg tgatttacgc atataggtta cgactacctt
     5461 tttggacttt agagtttgag acccccttat ccgctatata cgccttacta tcacgttcct
     5521 gttcgtaaag ccacgatttc gctatccctt cctctgacga ttcttatttc cagcgtcaga
     5581 cttaaaacgg tctatcccca gaccgtttta atccactacc tcacgatagt cgggcttggg
     5641 aatcgctatt tgactcgccg agaactttga catcagatat actataacaa attgaaataa
     5701 gaatcaaaca atttaatttt gaaattcaaa tcaatttata acaatatagt tgattgaaac
     5761 tagaatagta cacctctgct tctaaaacat tgttagaaat cgattttact gtcctgatcg
     5821 atttgtcctg ttctcatttc attttactat attttagaag atatgctgtg ctattccaga
     5881 ttcagtttgc tatacatgcc tgtcgtacca caaaatcccg tgtctgatga ggcacgggat
     5941 ttttggctct ataatatttg tagtgggtaa atcccttata gatattatgg agtctatttt
     6001 tgtgtagaaa aaaagtccca tatgacctat aatgaaaagc gat
//
LOCUS       DAVEHY010000066         6030 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVEHY010000066 DAVEHY010000000
VERSION     DAVEHY010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.066"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            106..948
                     /locus_tag="VUZ44_002093"
     CDS             106..948
                     /locus_tag="VUZ44_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU0320939.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            1221..1981
                     /locus_tag="VUZ44_002094"
                     /pseudo
     CDS             1221..1981
                     /locus_tag="VUZ44_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
     gene            2352..3269
                     /gene="glyQ"
                     /locus_tag="VUZ44_002095"
     CDS             2352..3269
                     /gene="glyQ"
                     /locus_tag="VUZ44_002095"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU0320940.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQDCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            3481..5517
                     /locus_tag="VUZ44_002096"
     CDS             3481..5517
                     /locus_tag="VUZ44_002096"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU0320941.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFRGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            5559..5816
                     /locus_tag="VUZ44_002097"
     CDS             5559..5816
                     /locus_tag="VUZ44_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU0320942.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         1863 a         1083 c         1361 g         1723 t
ORIGIN      
        1 aaataggtct gttagatatt tgacagactt attttttaca gaatatagta ctacttaaaa
       61 aatgttttat gctataattg atgaataaaa tagaaggaga agcatatgaa tacctatcaa
      121 ttaaataatg gagtagaaat tccagtattg ggatttggaa cttttaaggc taaggatgga
      181 gaagaagcct atcgtgcagt gttagaagcc ttgaaggctg gttatcgtca tattgatacg
      241 gcggcgattt atcagaatga agaaagtgtt ggtcaagcaa tcaaagatag cggagttcca
      301 cgtgaagaaa tgttcgtaac taccaagctt tggaatagtc agcaaaccta tgagcaaact
      361 cgtcaagctt tggaaaaatc tatagaaaaa ctgggcttgg attatttgga tttgtatttg
      421 attcattggc cgaacccaaa accgctcaga gaaaatgacg catggaaaac tcgcaatgcg
      481 gaagtttgga gagcgatgga agacctctat caagaaggga aaatccgtgc tatcggcgtt
      541 agcaattttc ttccccatca tttggatgcc ttgcttgaaa ctgcaactat cgttcctgcg
      601 gtcaatcaag ttcgcttggc gccaggtgtg tatcaagatc aagtcgtagc ttactgtcgt
      661 gaaaagggaa ttttattgga agcttggggg ccttttggac aaggagaact gtttgatagc
      721 aagcaagtcc aagaaatagc agcaaatcac ggaaaatcgg ttgctcagat agccttggcc
      781 tggagcttgg cagaaggatt tttaccactt ccaaaatctg tcacaacctc tcgtattcaa
      841 gctaatcttg attgctttgg aattgaactg agtcatgagg agagagaaac cttaaaaacg
      901 attgctgttc aatcgggtgc tccacgagtt gatgatgtgg atttctagaa aatcataaaa
      961 agaattgtac attattctaa tttttgatat aatagtcagc aggaaagaaa gtcttatggc
     1021 gttcttcaag cgagcttggg atagtgggag ccaagtaggg caaaataaag ggctggcgct
     1081 ttctgtagta ttttcaaaaa caatgaagta ataaattagg gtggaaccgc gtttctgacg
     1141 cccctaggtt aaatcaacct aggattgtca gatgtggttc ttttgcttat tcagtctatt
     1201 gtgtgaaaga aaggagagcc gtggacaacc tttatcttgt aaaagacgat agtcaactag
     1261 ctacatttcg tgattttgca gtaagaaata ctgaaaagtt gaaagattat caatcttttt
     1321 taaagaatga acttgcagtc tgtgatttac cgcaagctgt tatttggtca gattttaatg
     1381 ctgctacaca gattattagg gaaagtgctg ttccaaccta tacaaataat agacgagtgg
     1441 ttatgacgcc tgatttagct gtttggaaag aattgtattt gtatcagttg atggactacg
     1501 agtgttctga gcaaactcaa gcaatagaaa gtcactatca ttctttatct gaaaatttcc
     1561 tcttacagat tgtaggacat gagttagctc attggtcgga cattttttag atgattttga
     1621 tggttatgac tcttatatct ggttcgaaga ggggatggtt gaatatatta gtcgcaagta
     1681 tttcttgaca gaagaggaat ttcaagcgga aaaaatttgt aatcaatctc tcgtagaact
     1741 ttttcagaag aagtatagtt ggcattcatt gaatgatttt ggttcttcga cttatgataa
     1801 gaactatgca agtatttttt atgaatactg gcgcagcttt ttgacagtag ataagttggt
     1861 agaaaattta ggtagtgtac aagcggtctt agattcttat catttatggg caaatacaga
     1921 aaaaactttt cccttgttag attggtttgt tcagcagaaa ttaattgaaa aagaaatata
     1981 aaaactaaag gagtaaacaa tgtctaagaa attaacattt cactgcatca gtggcagaga
     2041 cctccttaca gtcgggctgc tccacgctca gcactagagt gcctgagcta gacgcagtac
     2101 taactcgtct tgcctcgtat gatcgacgag gcagactcgt gtcgcaagta attatttttt
     2161 attaaggagt attcaatgtc taagaaatta acatttcact gcgtcagtgg cagaaacctc
     2221 cttacagtcg gactgcccta cgctcagcac tagagtgcct gagctagacg cagtactaac
     2281 tcgtcttgcc tcgtataatc gacgaggcag actcgtgtcg caagaaatta ttttttatta
     2341 aggagtattc aatgtctaag aaattaacat ttcaagaaat tattttgact ttgcaacaat
     2401 tttggaatga ccaagattgt atgcttatgc aggcttatga taatgaaaaa ggtgcgggga
     2461 caatgagtcc ttacactttc cttcgtgcta tcggacctga gccatggaat gcagcttatg
     2521 tagagccatc acgtcgtcct gctgacggtc gttatgggga aaaccctaac cgtctctacc
     2581 aacaccacca attccaggtg gtcatgaagc cttctccatc aaatatccaa gaactttacc
     2641 ttgagtcttt ggaaaaattg ggaatcaatc ctttggagca cgatattcgt tttgttgagg
     2701 acaactggga aaacccatca actggttcag ctggtcttgg ttgggaagtt tggcttgacg
     2761 gaatggaaat cactcagttc acttatttcc aacaagtcgg tggattggca actggccctg
     2821 tgactgcgga agttacctat ggtttggagc gcttggcttc ttacattcaa gaagtagact
     2881 ctgtctatga tatcgagtgg gctgatggtg taaaatacgg agaaatcttt atccagcctg
     2941 agtatgagca ctcaaaatat tcatttgaaa tttcggacca agaaatgttg cttgaaaact
     3001 ttgataagtt tgaaaaagaa gctggtcgtg cattagaaga aggcttggta caccctgcct
     3061 atgactatgt tctcaaatgt tcacatacct ttaatctgct tgacgcgcgt ggtgccgtat
     3121 ctgtaacaga gcgtgcaggc tatatcgctc gtatccgtaa cttggcccgt gtcgtagcca
     3181 aaacctttgt cgcagaacgc aaacgcctag gctacccact tttggatgaa gaaacaagag
     3241 ctaaactcct agcagaagac gcagaataaa gagagtgaca aattacgaaa atgggcgaac
     3301 agagtgagcc ctgagccagt tgccgcagtg atgaaggtat ccttagtgaa actaaggata
     3361 ctaggcaaaa ttggagactt ttggctccaa ttttagcaat gaaacaacga agttggttgc
     3421 ttgcgtgcca atcacataag gcaaactgga aaataaaaag atacttttcg gagaaaaaac
     3481 atgacaaaaa acttattagt agaactcggt cttgaagaat taccagccta tgttgttacg
     3541 ccaagtgaaa aacaactagg cgaaaaaatg gcagccttcc tcaagggaaa acgcctgtct
     3601 tttgaagcca ttcaaacctt ctcaacacca cgtcgtttgg ctgttcgtgt aactggtctt
     3661 gcagacaaac agtctgattt gacagaagat ttcaggggtc cagcaaagaa aattgcctta
     3721 gatagtgatg gaaacttcac caaagcagct caaggatttg tccgtggaaa aggcttgact
     3781 gttgaagata tcgaattccg tgaaatcaag ggtgaagaat atgtctatgt cactaaggaa
     3841 gaagttggtc aagcagttga agccattgtt cctggtgttg tagatgtctt gaagtcattg
     3901 actttccctg tcagcatgca ctgggctgga aatagctttg aatacatccg ccctgttcac
     3961 actttaactg ttctcttgga tgagcaagag tttgacttgg atttccttga tatcaaggga
     4021 agtcgtgtga gccgtggcca tcgtttcttg gggaaagaaa ccaaaattca gtcagcattg
     4081 agctatgaag aagaccttcg taagcagttt gtaatcgcag atccatgtga acgtgagcaa
     4141 atgattgttg accaaatcaa ggaaattgag gcaaaacatg gtgtacgtat cgaaattgat
     4201 gcggatttgc tgaatgaagt cttgaatttg gttgaatacc caactgcctt catgggaagt
     4261 tttgatgcta aataccttga agttccagaa gaagtcttgg tgacttctat gaaggaacac
     4321 cagcgttact ttgttgttcg tgatcaagat ggaaaactct tgccaaactt catttctgtt
     4381 cgtaacggaa acgcagagcg tttgaaaaat gtcatcaaag gaaatgaaaa agtcttggta
     4441 gcccgcttgg aagacggaga attcttctgg cgtgaagacc aaaaattggt gatttcagat
     4501 cttgttgaaa aattaaacaa tgtcaccttc catgagaaga ttggttccct tcgtgaacac
     4561 atgattcgta cgggtcaaat cactgtactt ttggcagaaa aagctggttt gtcagtggat
     4621 gaaacagttg accttgctcg tgcagcagcc atttacaagt ttgacttgtt gacaggtatg
     4681 gttggtgaat ttgacgaact ccaaggaatt atgggtgaaa aatacaccct tcttgctggt
     4741 gaaactccag cggtggcagc tgctattcgt gaacactaca tgcctacatc agctgaagga
     4801 gaacttccag agagcaaggt cggcgcagtt ctagccattg cagacaaatt ggatacgatt
     4861 ttgagtttct tctcagtagg attgattcca tcaggttcta atgaccctta tgcccttcgt
     4921 cgtgcaactc aaggtgtggt tcgtatcttg gatgcctttg gttggcacat tgctatggat
     4981 gagctgattg atagccttta tgcattgaaa tttgacagtt tgacttatga aaataaagca
     5041 gaggttatgg actttatcaa ggctcgtgtt gataagatga tgggctctac tccaaaagat
     5101 atcaaggaag cagttcttgc aggttcaaac tttgttgtgg cagatatgtt ggaagcagca
     5161 agtgctctcg tagaagtaag caaggaagaa gattttaaac catctgttga atcactttct
     5221 cgtgccttta acctggctga gaaggcagaa ggggttgcta cagttgattc agcactattt
     5281 gagaatgacc aagaaaaagc tttggcagaa gcagtagaaa cactcgtttt atcaggacct
     5341 gcaagtcagc aattgaaaca actctttgcg cttagcccag tcattgatgc tttctttgaa
     5401 aatactatgg taatggctga agatcaggct gtccgtcaaa atcgtttggc aatcttgtca
     5461 caactaacca agaaagcagc taagtttgct tgttttaacc aaattaacac taaataaaat
     5521 ttgataaacg gactttatct tattacaaag gagaagaaat ggatccgaaa aaaattgctc
     5581 gtatcaatga gcttgctaaa aagaaaaaaa cagaaggctt aacaccagaa gaaaaagtgg
     5641 aacaagccaa actacgtgag gagtacatcg aaggttatcg ccgcgctgtt cgtcaccaca
     5701 ttgaaggaat caaaattgtg gacgaagaag gaaacgatgt tacaccagaa aaactacgcc
     5761 aagtacaacg tgaaaaagga ttacatggcc gtagtcttga tgacccaaat tcataataat
     5821 actcttcgaa aatcaaattc aaaccacgtc agcttcacct tgccgtactt aagtacagcc
     5881 tgcggctagc ttcctagttt gctctttgat tttcattgag tataagtatt ctttctttta
     5941 acaaggatag atgaaacgat aacaaagaga ctagcagttt gtgtttgtta gtcttttttc
     6001 gctaaaaaag gaaccataat ggttcctaaa
//
LOCUS       DAVEHY010000067         5813 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVEHY010000067 DAVEHY010000000
VERSION     DAVEHY010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.067"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(252..632)
                     /locus_tag="VUZ44_002098"
     CDS             complement(252..632)
                     /locus_tag="VUZ44_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEU0320943.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(778..2130)
                     /locus_tag="VUZ44_002099"
     CDS             complement(778..2130)
                     /locus_tag="VUZ44_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEU0320944.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLVKLRAKEAIFEKFEQSLNEKYNRMSNSGEEQEYYGKVEYYLSQLNSENYNN
                     STQYSKIQDEYTKLNKITAERNQLDADLQTLQNELLQLQQQGDSPSLSDTTSADDKAK
                     LETKILEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(2127..2594)
                     /locus_tag="VUZ44_002100"
     CDS             complement(2127..2594)
                     /locus_tag="VUZ44_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU0320945.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(2587..4806)
                     /locus_tag="VUZ44_002101"
     CDS             complement(2587..4806)
                     /locus_tag="VUZ44_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU0320946.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIHKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYENMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            5272..>5813
                     /locus_tag="VUZ44_002102"
     CDS             5272..>5813
                     /locus_tag="VUZ44_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0320947.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGK"
BASE COUNT         1908 a         1156 c          797 g         1952 t
ORIGIN      
        1 taatctacca acctcttgtt tttaaataca tttcaagtcc aaactattct ttatagaaaa
       61 aagtcctata aattcgagca atagttaaaa tacaaacaaa tataattccc aaaatagata
      121 acactatttt cacaaaattc atttcagaac ctattatata tacgtgaaaa aaaggggcta
      181 ttcctacaca tatatacaat aaataactta caaagtttat ttcaccaatt cctgcaaaaa
      241 aatgtttcat tttaagcaaa aatataacca tctaagctac cgtcagccca atcagcccca
      301 tatgcgattg ctccacctag tgaaaatcca gtaacagtta gtgcaacgtt tagtgcagta
      361 ttgactaaat ggccagctgc actacctaca tgtttaatta ttaaactacg taatgttctc
      421 gtaatagccc ctctattagc tgagatagct ttttttatcg cataagcaga ataaattgtt
      481 gcaccaccac tatagatggc caaacctaca tccagaactg ttgcaaaact acctctacta
      541 ttccaccagt tacgaccaac accaccccca tcaagataca tcatctcttc ttgctcaaga
      601 gcaacataat tatttggtaa tacgagttcc atttattttc tcctttttta ttaagcatgg
      661 ttaggatagt ttcctaacaa gtgagcatcg actttgttta tagcacttag ttacctagat
      721 aagatatctt ccctttatct tactttattt tataggtgac ttaatgttta aaaccaatta
      781 ttgcttgaaa cttaacattt ccaaaatcca atcaagatag gtttctttat catagacaat
      841 ccgcacttca actggcatat ccttttggag gacgactgtc tcacttccat gttttagagt
      901 taaggtttct aattctatca tgactttata aagactaata ttgccctctt tcgtttcttg
      961 ggaaattgtt cctgaatcaa tctgtctgac ttgtcccttt agtgttccat atttttgact
     1021 atttacacca gtaatagcaa catcagcttt tgctcctttc gaaacacgag aaatatcact
     1081 cgcaagtaca aaagcttcta catagtaacc tttttctttc cctgaaactt ctgctatcgt
     1141 ttgcccctgc tgaatagaca ttccttgttt caaaggtacc aaataatgca gagtaccttc
     1201 atttggcgct aatatactat gagctttatc ttgacctgtt gccactccaa gattagcctc
     1261 aagctctgta atacttttat tgttgtttga acgagcagta cctaactcac taactaattg
     1321 agcataaata ttataagcct gagaagttgg atcattatag gtacggttca tatctttaat
     1381 attgctttgt tgactatcaa tctcgctatt cttagaagta atatttgttt ttaatgcttc
     1441 gatttttgtt gttatttcta atatcttagt ttctaactta gctttatcat cagctgatgt
     1501 cgtatctgat aaggaagggg agtctccttg ctgttgaagt tgaagcaatt cattttgtag
     1561 agtttgcaag tcggcatcta actgatttct ttcagctgtt attttattca acttcgtata
     1621 ttcatcctga atctttgaat actgggtact attattataa ttttccgaat ttaactgaga
     1681 taggtagtat tcaactttcc cataatattc ctgttcttca ccagaattag acatacggtt
     1741 gtatttctca tttaatgatt gttcaaattt ttcaaagata gcttcttttg cacgtaactt
     1801 caccaattgt ttatttaaag agctcgcttg taaaccttct tgtccacttg ataacgaaat
     1861 aatgacatct ccagcattta ccatatctcc ttctgactta tgtaaagtaa ctaccttccc
     1921 tgaaccaatt gctgatagga actctgtacc tgttataact gaatttccat tcgcttttac
     1981 aatatagttt ttgggtatat aagctgcgcc aaccaatgca ccgcttaaga taatagcagt
     2041 tgaaataatg agaataaacg caaaagctgg tggtctctta tcaaagaaaa tacgagaata
     2101 acgtaattct gatttattat ataatttcat aggcttacaa ttggtctaaa aatatctact
     2161 accatttttt caggagaaga attaacataa actgtataga caatcccatc cgtttgaata
     2221 tcattttcat agacatatag atccaattta gaatacgcat actgtagata ctctggactg
     2281 tcttcaaaac gaacatataa acaatatgga acagagatag aatcctgtac atcataaatg
     2341 ttactgtact gttgagcatt atgagcttga atataaaact caaaatcagt cgttattaat
     2401 ccatcatcat gaatagtagt accacaactt tttacaatta atggaccaaa aatttgtgct
     2461 tttaacaact gcaaatgttg atgaaattta ttaatttcct gatctacatc ttctactttt
     2521 gtatcatgta actttttaca gataactgac tttagtacca gttttttatt atcttttacc
     2581 tctaacttag ccataagtaa cctcctctgt atctaacaca gcctgtgact gaatttgttg
     2641 attcacttga acgctctgca aaccaaccat tctagcatac tttccatttt tcgccattag
     2701 ttcttcatga gtcccatatt ccacaatagt cccattttct aaaaagcata tcttatcaca
     2761 tcgaagaatt gtagacagcc tgtgggctac tacaattgtt gtcttatcca ttattttatt
     2821 aaagattaaa tcctgaataa tctgttcact aaatgaatct aagttagagg ttgcctcatc
     2881 aaatatatac aaatcagctt tactcagtag tgctcttgca atagccaatc gttgtttctc
     2941 tccacccgag aaattttgac cgccttcttc tacaaaggag ccataacgat tttgaagacg
     3001 ttgaatcgta tcatgaatac caacaatacg acaaactctc accatattct catatgtaac
     3061 agaaggatta ccaattttta gattatcaat aattgtccct gtaaagagtt ctatggtctg
     3121 aggaatgtag gaaattttct tacgtagttt accatagtca agatctgata agtcattttc
     3181 tcctatacga attttcccct cactcggatt tataaatctt aataacaaac gaactagcgt
     3241 actttttcct gctccgcttt ctccaacaaa agctattttt tctccttgtt taattcgcaa
     3301 attaaagtcc ttgataacag gagggcgtga accataggca aatgttacat ctttaaattc
     3361 aatgtcatca cataaggtga agtctctaat actataatcc aaggcaatgt cttcacgatc
     3421 tacttccatc aattcttgaa gccgactaac cgcaacctgt acctcttgaa aggttaactg
     3481 caagccaact aaattctgaa taggttctgt aaaatattga cttaatgtct gaaaaaccaa
     3541 gaggtcccca atagtcattt ttccatcaat gataaataag gcgcccactc ccataaataa
     3601 taacccaccc atggttgagg tcattgaaga tattgtagat tgaatattct gcaaaacacc
     3661 ctctttataa ccaatttcta aagtgtgaac aaatttttct tcaattttgt ttaaacgttg
     3721 ttcctcatca tgctgagact taatggtatc aatgttacga atagattcaa ttaactgtga
     3781 attaagaagt ccatttgctt ccatttgttc atgattaatt tttttataag gctttttaaa
     3841 acagtatata agaatgatgt taacaataac cataaaaact aatatcagaa ataaagattg
     3901 attaatagtc caaaggacaa ccgcactaat aactgacaag gtgatatcca tgactaatga
     3961 aatagagact gacgtaaaca cattctttat cgtcatcgca tcttgaaatc ttgttaaaac
     4021 atcaccaact ctacgacttc caaaaaaact ataaggaaga tgaataatat ggtcataata
     4081 tcccattaaa accggtatat caatttttcg agatagaaac aaaagaacgt gctgacgaaa
     4141 tgcagataga agagtctgta agaacgacac tattccaaat actatcaaaa acatatacag
     4201 actatttttt aaagcatatg gaatcacctc gtccatgata acttttgaaa agagactcga
     4261 taaaatacca atgatactta aaacaaagga agctaatatg actgtactaa tcaatccttt
     4321 ttgattaaaa attaaccttc caaataaatc aagaagtcct tttcccttta gtttccctct
     4381 ttcaaaatcc gaatttggaa ccataaaaag agtaatacct tgataaattt ctcccagttc
     4441 gtcacttgac atcttgtgta tgccactagc agggtctgct acgtagaact tactattcct
     4501 tttgatacta tgtaatacca caaaatgatt ttgacctaaa tcattcttaa cttgaagaat
     4561 cgcaggaaat gttaattttg gagtcaaatc ttccagtgct actcgaacag cttttactgt
     4621 aaaattcaac ttattcagac ctgaaacaat accactgaca gtcgttccat acatgtctgt
     4681 accaataatt tccctaatct tcatgattga tagttccttt ttgtaagata aaagaactgt
     4741 tgaaacaact gccgcagcac aatctgactg gtcatgttgc atcgtacaag gatatttttt
     4801 taacatagaa atactcaatt ctttagaatt aatctaactt ttctttgatg tcacccaaac
     4861 ctcaatcact gcccagtagt tcttgaatta atttattttc aaccgtatca ttctttgttc
     4921 ttgatatctt tccaagcatt gtagtacagc agatttttgc ccaaggactg agcctccttt
     4981 aacaactcaa actcccttac attatatcgg ccagccccat ggaaagatta tagccagact
     5041 aatcaataat ataatacata ctagaataca aaatattttt ttattcatac tttttctcct
     5101 atctttattt tctacctaca tagtacctct tattaagctc attttaaaat tacgttaact
     5161 tttttcacaa atttatttcg actttctttt ttacttttta cattgctatg atacaatatt
     5221 tttaacaaaa ttttattgtt tgttaacttt tttcacgaaa aggagaaaat catgcgttat
     5281 gatttcggaa aggtctataa agaaatacgt gagtcaaagg ggctgaccca agaagaggtc
     5341 tgtgggggtg ttctctcaag aaccagctta tcaaaaatcg aaagtggcaa gacaacccca
     5401 aaatatgaaa atatggaatt tcttctccgt caaatcaata tgagttttga agagtttgaa
     5461 tatatctgtc aactttatca accaagtcaa cgcacagaga ttatgcaaac ctatctcaat
     5521 atgcgttcca ttatcgggac cagcgatctt gtcaatttat ttcaaaaatg ccaagactac
     5581 ctcaagaccc accacgatct ccctatagaa gaaatcagag atatgcttga agttgttatt
     5641 tatctccgtc aacacggggc aggggaacta tcaaaacacg cagaacaggt tgtcaaaaaa
     5701 ctttggaaaa aaattgaaaa acaagataca tggtatgaga gtgatctaaa aatcctcaat
     5761 accattcttt tcagttttcc cattgaatac ctccatctca tcactggaaa aat
//
LOCUS       DAVEHY010000068         5416 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVEHY010000068 DAVEHY010000000
VERSION     DAVEHY010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.068"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            159..1166
                     /gene="gap"
                     /locus_tag="VUZ44_002103"
     CDS             159..1166
                     /gene="gap"
                     /locus_tag="VUZ44_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU0320948.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(1234..2070)
                     /locus_tag="VUZ44_002104"
     CDS             complement(1234..2070)
                     /locus_tag="VUZ44_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU0320949.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            2196..4391
                     /locus_tag="VUZ44_002105"
     CDS             2196..4391
                     /locus_tag="VUZ44_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU0320950.1"
                     /translation="MKLDELFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQSLAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            4444..4596
                     /gene="rpmG"
                     /locus_tag="VUZ44_002106"
     CDS             4444..4596
                     /gene="rpmG"
                     /locus_tag="VUZ44_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU0320951.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            4606..4782
                     /gene="secE"
                     /locus_tag="VUZ44_002107"
     CDS             4606..4782
                     /gene="secE"
                     /locus_tag="VUZ44_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU0320952.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            4837..5373
                     /gene="nusG"
                     /locus_tag="VUZ44_002108"
     CDS             4837..5373
                     /gene="nusG"
                     /locus_tag="VUZ44_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU0320953.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         1682 a          962 c         1180 g         1592 t
ORIGIN      
        1 acagtcttaa aaagaaacta acatagaaaa acaatggcca tacttgcaat tcaactcaaa
       61 tagttgtata ataggtttgt tgaaaggtga tttgtagtga ttcaagttac tcttttcaca
      121 ataaaaattt catgattttc ataaggagga aatcactaat ggtagttaaa gttggtatta
      181 acggtttcgg acgtatcggt cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg
      241 aagttacacg catcaacgac cttacagatc cagttatgct tgcacacttg ttgaaatacg
      301 acacaactca aggtcgtttc gacggtactg ttgaagttaa agaaggtgga tttgaagtta
      361 acggtaaatt catcaaagtt tctgctgaac gtgatccaga acaaatcgac tgggctactg
      421 acggtgtaga aatcgttctt gaagctactg gtttctttgc taagaaagaa gcagctgaaa
      481 aacaccttaa aggtggagct aaaaaagttg ttatcactgc tcctggtgga aacgacgtta
      541 aaacagttgt attcaacact aaccacgacg ttcttgacgg tactgaaaca gttatctcag
      601 gtgcttcatg tactacaaac tgcttggctc caatggctaa agctcttcaa gacaactttg
      661 gtgttgttga aggattgatg actactatcc acgcttacac tggtgaccaa atgatccttg
      721 acggaccaca ccgtggtggt gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc
      781 ctaactcaac tggtgctgca aaagctatcg gtcttgtaat cccagaattg aatggtaaac
      841 ttgatggatc tgcacaacgc gttccaactc caactggatc agttactgaa ttggtagcag
      901 ttcttgaaaa gaacgttact gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg
      961 aatcatacgg ttacacagaa gatccaatcg tatcttcaga tatcgtaggt atgtcttacg
     1021 gttcattgtt tgacgcaact caaactaaag ttcttgacgt tgacggtaaa caattggtta
     1081 aagttgtatc atggtacgac aacgaaatgt catacactgc acaacttgtt cgtactcttg
     1141 aatacttcgc aaagattgct aaataattct tgagttgata gaaagcaagg ctttgtggtc
     1201 ttgctttttt atatggaaaa atggatgaca cgatcatcca ttctttttta attctttttc
     1261 aaatgtattt gaaagggtag tgaaagttag cctctctaaa gtaagtgggt gggtaaagga
     1321 aagtcggaag gcatgaagca taagccggct tgtctttgat ttactattat agagagggtc
     1381 tcccaggata ggaagattat gatgcaaaag gtgcacacga atctgatggg ttcgccctgt
     1441 ctttagcttg caatgagcca aggaagtctt gtttgagaat tgctttaatc tgcttacatg
     1501 cgtttcagca tattgcccat tttttgcatc aactattctt tttctacgat catggcgatc
     1561 acgtccaatt ttgtctctga aaacaagttc ttttctgttg atatttccat caactagagc
     1621 ccaatattct ctagaaatct cttttttctc caataagcga ttgagaatgg gcaggataaa
     1681 aggatttttg gcaaagagaa ctaagccact ggtttccatg tccagacgat gaacgacata
     1741 gcaggtttgg ccaacatagg tactgacatg gttaagaagg gcaatttcgt ttggttgatt
     1801 accatgcgtt ttcatcccct ctggtttgtt tacaataatc aagtgttgat cttgataaac
     1861 ttcctgcact aagtctgggt tgccccaagg gatcgtcttt tgggaataat cttcctcgtc
     1921 aaaagtcaac tggcaaacat ctccaggatt tacgatttcg ttccagtgga cttcttcttg
     1981 atttatcaaa atatgtttct tgattctcaa aaaatgacgg atttttctag ggatgaggag
     2041 ttgttcctca agtaattgct ttaccgtcat ttgaggtaga gaggcgggta atgtaaatgt
     2101 gaattgcata cagatattgt aacaaaaaaa gccctatttg gataggaaat agctaaattc
     2161 ttgtcttcct atgatgaaga tgataaaata aacgcatgaa attagatgaa ttatttgaga
     2221 aatttctttc tctttttaaa aaagaaacaa gtgaactaga ggactctgat tctactatct
     2281 tacgtcgctc tcgtagtgat cgaaaaaaat tagcccaagt aggtccgatt cgaaaattct
     2341 ggcgtcgtta tcatctaaca aagattatcc ttatactagg tttgagtgca ggattgctag
     2401 ttggaatcta tttgtttgct gtagccaagt cgaccaatgt caatgatttg caaaatgcct
     2461 tgaaaactcg gactcttatt tttgaccgtg aagaaaaaga ggctggtgcc ttgtctggtc
     2521 aaaagggaac ctatgttgag ctgactgaca tcagtaaaaa cttgcagaat gctgttattg
     2581 cgacagaaga ccgttctttc tataaaaatg acgggattaa ctatggccgt ttcttcttgg
     2641 ctattgtcac tgctggacgt tcaggtggtg gctctaccat tacccaacag ctggctaaaa
     2701 acgcctattt atcgcaggat caaactgttg agagaaaagc gaaagaattt ttccttgcct
     2761 tagaattaag caaaaaatat agtaaggagc aaattctaac catgtacctt aacaacgctt
     2821 attttggaaa tggtgtgtgg ggtgtagaag atgcgagtaa gaaatacttt ggagtttctg
     2881 catcagaagt gagtctggat caagctgcga ctctggcagg gatgctcaag gggccggaac
     2941 tgtataatcc cttgaattcc gtagaagatt ctactaatcg gcgcgatact gtcttgaaga
     3001 atatggttgc agcaggatat attgataaaa accaagaaac cgaagctgct gaagttgata
     3061 tgacttcgca attgcacgat aagtatgaag gaaaaatctc agattaccgt tacccctctt
     3121 attttgatgc ggtggttaat gaagctgttt ccaagtataa tctaacagag gaagagattg
     3181 tcaataatgg ctaccgcatt tacacagagc tggaccaaaa ctaccaagca aatatgcaga
     3241 ttgtttatga aaacacatcg ctatttccga gggcagagga tggaacgttt gctcaatcag
     3301 gaagtgtagc tctcgaaccg aaaacagggg gagttcgtgg agttgtcggt caagttgctg
     3361 acaatgataa aactggattc cggaatttca actatgcaac ccaatcaaag cgtagtcctg
     3421 gttctacaat taagccttta gttgtttata caccagcagt tgaagcaggc tgggctttga
     3481 ataagcagtt ggataaccat accatgcagt atgatagcta taaggttgat aactatgcag
     3541 ggatcaaaac aagtcgagaa gttcctatgt atcaatcctt ggcagaatcg cttaatctac
     3601 ctgctgttgc cactgttaat gatttgggtg ttgacaaggc ttttgaggca ggcgaaaaat
     3661 tcggactcaa catggaaaag gtcgaccgtg ttcttggtgt cgccttggga agcggtgttg
     3721 aaaccaaccc tcttcaaatg gctcaagcat acgctgcctt tgcaaatgaa ggtttaatgc
     3781 ctgaagctca ttttattagt agaattgaaa atgctagtgg acaagttatt gcgagtcata
     3841 aaaattcaca aaaacgggtg attgataagt ctgtagctga caagatgacc agtatgatgt
     3901 tggggacttt caccaacggt accggtatta gttcatcgcc tgcagactat gtcatggcag
     3961 ggaaaactgg aacaactgaa gcagttttca atccggagta cacaagtgac cagtgggtaa
     4021 ttggttatac tccggatgta gtgattagcc actggcttgg ctttccgacc actgatgaaa
     4081 atcactatct agctggctct acttcaaacg gtgcagctca tgtctttaga aacattgcca
     4141 ataccatttt accttatacg ccaggaagta cctttacggt tgaaaatgct tataagcaaa
     4201 atggaattgc accagccaat acaaaaagac aagtacaaac caatgataat agccagacag
     4261 atgataattt gtctgatatt cgagggcgtg cgcaaagtct agtagatgag gctagccggg
     4321 ctatctcaga tgcgaagatt aaggaaaagg ctcaaacaat atgggattcg atagtcaatc
     4381 tatttcgcta agatgcttgt caaagcctag ctttcttgtt ataatggata agatggaggc
     4441 gttatggcac taaaaaaagc aagcctagct tgtgcggttt gtggttcgag aaactattca
     4501 atcaagatca gcggaaaccc caagcctaca cgactagaag taaataaatt ttgtaagcat
     4561 tgtggcaagt acactacaca cagagaaacg agataggaga gagcgatgcg ttttattgga
     4621 gatattttta gacttcttaa agacacaaca tggccaactc gcaaggaaag ctggagagat
     4681 tttcgttcta tcatggaata cacagctttc tttgtagtaa ttatttacat ttttgaccag
     4741 ttgattgttt caggtttgat tcgatttatt aacatttttt agaagattag tggagttaat
     4801 tacactagaa atcttctatt tatgaaagga aatatcatgg atagttttga taaaggatgg
     4861 tttgttttac aaacttattc tggttatgaa aataaggtga aagaaaatct attacaacgt
     4921 gcacaaacct acaatatgtt ggataatatt ctacgcgttg aaattccaac acaaacagtg
     4981 caagttgaaa aaaatggaaa gagaaaagaa gtagaagaaa atcgctttcc aggttatgtt
     5041 cttgtagaaa tggtcatgac agatgaagct tggtttgttg ttcgaaacac accaaatgtt
     5101 acaggatttg tcggatcaca cgggaacaga tcaaaaccaa ctccattatt ggaacaagaa
     5161 attcgtgaca ttttggtatc tatgggacaa actgttcaag aatttgattt cgatgttgag
     5221 attggtcaaa ctgtacgtat tattgatggt gcttttgcag actacactgg taagattaca
     5281 gaaattgata ataacaaagt gaaaatgatt atctctatgt ttggtaatga cacagttgca
     5341 gaagtaaacc taaaccaaat cgcagaatta taaccctgag agaggctgga gcctctcttt
     5401 tttgtgcagt ttagga
//
LOCUS       DAVEHY010000069         5124 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVEHY010000069 DAVEHY010000000
VERSION     DAVEHY010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.069"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            254..1799
                     /locus_tag="VUZ44_002109"
     rRNA            254..1799
                     /locus_tag="VUZ44_002109"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1851..1923
                     /locus_tag="VUZ44_002110"
     tRNA            1851..1923
                     /locus_tag="VUZ44_002110"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1884..1886,aa:Ala,seq:tgc)
     gene            2048..4949
                     /locus_tag="VUZ44_002111"
     rRNA            2048..4949
                     /locus_tag="VUZ44_002111"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5026..>5124
                     /gene="rrf"
                     /locus_tag="VUZ44_002112"
     rRNA            5026..>5124
                     /gene="rrf"
                     /locus_tag="VUZ44_002112"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1457 a         1036 c         1497 g         1134 t
ORIGIN      
        1 tatggtatgt tgcgtcagga gcacttgatg aaaaaaagtt taaaaaaact taaaaatctt
       61 caaaaaagtg ttgacaagcg aaagcagttg tgatatacta atatagttgt cgcttgagag
      121 aagcaagtga caaagacctt tgaaaactga acaagacgaa ccaatgtgca gggcgctaca
      181 acataagttg tagtactgaa caatgaaaaa acaataaatc tgtcagtgac agaaatgagt
      241 gagaactcaa acttttaatg agagtttgat cctggctcag gacgaacgct ggcggcgtgc
      301 ctaatacatg caagtagaac gctgaaggag gagcttgctt ctctggatga gttgcgaacg
      361 ggtgagtaac gcgtaggtaa cctgcctggt agcgggggat aactattgga aacgatagct
      421 aataccgcat aagagtagat gttgcatgac atttgcttaa aaggtgcact tgcatcacta
      481 ccagatggac ctgcgttgta ttagctagtt ggtggggtaa cggctcacca aggcgacgat
      541 acatagccga cctgagaggg tgatcggcca cactgggact gagacacggc ccagactcct
      601 acgggaggca gcagtaggga atcttcggca atggacggaa gtctgaccga gcaacgccgc
      661 gtgagtgaag aaggttttcg gatcgtaaag ctctgttgta agagaagaac gagtgtgaga
      721 gtggaaagtt cacactgtga cggtatctta ccagaaaggg acggctaact acgtgccagc
      781 agccgcggta atacgtaggt cccgagcgtt gtccggattt attgggcgta aagcgagcgc
      841 aggcggttag ataagtctga agttaaaggc tgtggcttaa ccatagtagg ctttggaaac
      901 tgtttaactt gagtgcaaga ggggagagtg gaattccatg tgtagcggtg aaatgcgtag
      961 atatatggag gaacaccggt ggcgaaagcg gctctctggc ttgtaactga cgctgaggct
     1021 cgaaagcgtg gggagcaaac aggattagat accctggtag tccacgctgt aaacgatgag
     1081 tgctaggtgt tagacccttt ccggggttta gtgccgtagc taacgcatta agcactccgc
     1141 ctggggagta cgaccgcaag gttgaaactc aaaggaattg acgggggccc gcacaagcgg
     1201 tggagcatgt ggtttaattc gaagcaacgc gaagaacctt accaggtctt gacatccctc
     1261 tgaccgctct agagatagag ttttccttcg ggacagaggt gacaggtggt gcatggttgt
     1321 cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa cgagcgcaac ccctattgtt
     1381 agttgccatc attcagttgg gcactctagc gagactgccg gtaataaacc ggaggaaggt
     1441 ggggatgacg tcaaatcatc atgcccctta tgacctgggc tacacacgtg ctacaatggc
     1501 tggtacaacg agtcgcaagc cggtgacggc aagctaatct cttaaagcca gtctcagttc
     1561 ggattgtagg ctgcaactcg cctacatgaa gtcggaatcg ctagtaatcg cggatcagca
     1621 cgccgcggtg aatacgttcc cgggccttgt acacaccgcc cgtcacacca cgagagtttg
     1681 taacacccga agtcggtgag gtaaccgtaa ggagccagcc gcctaaggtg ggatagatga
     1741 ttggggtgaa gtcgtaacaa ggtagccgta tcggaaggtg cggctggatc acctcctttc
     1801 taaggataag gaactgcgca ttggtcttgt ttagtcttga gaggtcttgt ggggccttag
     1861 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
     1921 ccattggtga gagatcacca agtaatgcac attgaaaatt gaatatctat atcaaatagt
     1981 aacaagaaaa taaaccgaaa acgctgtagt attaataaga gtttatgact gaaaggtcag
     2041 aaaataaggt taagttaata agggcgcacg gtggatgcct tggcactagg agccgacgaa
     2101 ggacgtgaca aacgacgata tgccttgggt agctgtaagt aagcgatgat ccagggattt
     2161 ccgaatgggg gaacccaaca ggtaatacct gttacccaca tctgttaagg atgtgaggag
     2221 gaagacgcag tgaactgaaa catctaagta gctgcaggaa gagaaagcaa aagcgattgc
     2281 cttagtagcg gcgagcgaaa cggcagaagg gcaaaccgaa gagtttactc ttcggggttg
     2341 taggactgca atgtggactc aaagattata gaagaatgat ttgggaagat cagccaaaga
     2401 gagtaatagc ctcgtattta aaatagtctt tgtacctagc agtatcctga gtacggcggg
     2461 acacgtgaaa tcccgtcgga atctgggagg accatctccc aaccctaaat actccctagt
     2521 gaccgatagt gaaccagtac cgtgagggaa aggtgaaaag caccccggga ggggagtgaa
     2581 atagaacctg aaaccgtgtg cctacaacaa gttcgagccc gttaatgggt gagagcgtgc
     2641 cttttgtaga atgaaccggc gagttacgtt atgatgcgag gttaagttga agagacggag
     2701 ccgtagggaa accgagtctg aatagggcgc cttagtatca tgacgtagac ccgaaaccat
     2761 gtgacctacc catgagcagg ttgaaggtgc ggtaagacgc actggaggac cgaaccaggg
     2821 cacgttgaaa agtgcttgga tgacttgtgg gtagcggaga aattccaaac gaacttggag
     2881 atagctggtt ctctccgaaa tagctttagg gctagcgtcg acattagaga ttcttggagg
     2941 tagagcactg tttgggtgag gggtccatcc cggattacca atctcagata aactccgaat
     3001 gccaatgaat tatggtcggc agtcagactg cgagtgctaa gatccgtagt cgaaagggaa
     3061 acagcccaga ccaccagcta aggtcccaaa ataattgtta agtggaaaag gatgtggggt
     3121 tgcacagaca actaggatgt tagcttagaa gcagctattc attcaaagag tgcgtaatag
     3181 ctcactagtc gagtgaccct gcgccgaaaa tgtaccgggg ctaaaacaat ttaccgaagc
     3241 tgtggatacc tttataggta tggtaggaga gcgttctatg tgtgatgaag gtataccgtg
     3301 aggagtgctg gaacgcatag aagtgagaat gccggtatga gtagcgaaag acaggtgaga
     3361 atcctgtcca ccgtaagact aaggtttcca ggggaaggct cgtccgccct gggttagtcg
     3421 ggacctaagg agagaccgaa aggtgtatcc gatggacaac aggttgatat tcctgtacta
     3481 gagtatgtag tgatggaggg acgcagtagg ctaactaaag cagacgattg gaagagtctg
     3541 tctaagcagt gaggtgtgaa ttgagtcaaa tgcttaattc tataacattg agctgtgatg
     3601 gggagcgaag tttagtagcg aagttagtga cgtcacactg ccaagaaaag cttctagcgt
     3661 ttaaacatac tctacccgta ccgcaaaccg acacaggtag tcgaggcgag tagcctcagg
     3721 tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt cgggagaagg
     3781 ggtgctgact taaagtcagc cgcagtgaat aggcccaagc aactgtttat caaaaacaca
     3841 gctctctgct aaatcgtaag atgatgtata gggggtgacg cctgcccggt gctggaaggt
     3901 taagaggagt gcttagcgta agcgaaggta tgaattgaag ccccagtaaa cggcggccgt
     3961 aactataacg gtcctaaggt agcgaaattc cttgtcgggt aagttccgac ccgcacgaaa
     4021 ggcgtaatga tttgggcact gtctcaacga gagactcggt gaaattttag tacctgtgaa
     4081 gatgcaggtt acccgcgaca ggacggaaag accccatgga gctttactgc agtttgatat
     4141 tgagtgtctg taccacatgt acaggatagg taggagtcta agagatcggg acgccagttt
     4201 cgaaggagac gctgttggga tactaccctt gtgttatggc cactctaacc cagataggtg
     4261 atccctatcg gagacagtgt ctgacgggca gtttgactgg ggcggtcgcc tcctaaaagg
     4321 taacggaggc gcccaaaggt tccctcagaa tggttggaaa tcattcgcag agtgtaaagg
     4381 tataagggag cttgactgcg agagctacaa ctcgagcagg gacgaaagtc gggcttagtg
     4441 atccggtggt tccgtatgga agggccatcg ctcaacggat aaaagctacc ctggggataa
     4501 caggcttatc tcccccaaga gttcacatcg acggggaggt ttggcacctc gatgtcggct
     4561 cgtcgcatcc tggggctgta gtcggtccca agggttgggc tgttcgccca ttaaagcggc
     4621 acgcgagctg ggttcagaac gtcgtgagac agttcggtcc ctatccgtcg cgggcgtagg
     4681 aaatttgaga ggatctgctc ctagtacgag aggaccagag tggacttacc gctggtgtac
     4741 cagttgtctt gccaaaggca tcgctgggta gctatgtagg gaagggataa acgctgaaag
     4801 catctaagtg tgaaacccac ctcaagatga gatttcccat gattatatat cagtaagagc
     4861 cctgagagat gatcaggtag ataggttaga agtggaagtg tggcgacaca tgtagcggac
     4921 taatactaat agctcgagga cttatccaaa gtaactgaga atatgaaagc gaacggtttt
     4981 cttaaattga atagatattc aattttgagt aggtattact cagagttaag tgacgatagc
     5041 ctaggagata cacctgtacc catgccgaac acagaagtta agccctagaa cgccggaagt
     5101 agttgggggt tgccccctgt gaga
//
LOCUS       DAVEHY010000070         4876 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVEHY010000070 DAVEHY010000000
VERSION     DAVEHY010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.070"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            53..415
                     /locus_tag="VUZ44_002113"
     CDS             53..415
                     /locus_tag="VUZ44_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU0320954.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     STINVLELLDKSQPFEEE"
     gene            1460..2452
                     /locus_tag="VUZ44_002114"
     CDS             1460..2452
                     /locus_tag="VUZ44_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU0320955.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2454..3272
                     /locus_tag="VUZ44_002115"
     CDS             2454..3272
                     /locus_tag="VUZ44_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU0320956.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3274..4059
                     /locus_tag="VUZ44_002116"
     CDS             3274..4059
                     /locus_tag="VUZ44_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU0320957.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4157..4375
                     /locus_tag="VUZ44_002117"
     CDS             4157..4375
                     /locus_tag="VUZ44_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU0320958.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4360..4521
                     /locus_tag="VUZ44_002118"
     CDS             4360..4521
                     /locus_tag="VUZ44_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU0320959.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
BASE COUNT         1400 a          798 c         1025 g         1653 t
ORIGIN      
        1 acctgcggct agtttcctag tttgctcttt ggttttcatt gagtataaca cattgttaga
       61 agttggttta aatttcctaa tcagtttgtt cacatttacc ttcgatatat tatatcccat
      121 agttaaggtt ggtcatacag atgattatag ccatggagcc gtaaaactta gtgtttcttt
      181 agttgacaaa gatgccatga aaaaaatatc tgtaactgta ataggatatt ttgaaataaa
      241 tatagatgaa aatatcaccg atattctata cgtaaatggt actgctattc tttatcctta
      301 tttacgttct attgtttcaa tagtttcggc aattgatagc agtgaagcaa tgttgctatc
      361 taccattaat gttttagagt tactagataa atctcaacct tttgaagaag aataatttat
      421 tagctcacta aattgagggt aaggaaaagt aaaagcagta agaaaaatgt cttgcattat
      481 acagcaactt tttgggaatg agtagatgga ttgaataaaa tttgattaag agtggatgat
      541 ttatctgtag attattattg gacagttagt cttgaagtag tctaagaatt aggttataat
      601 cagtagaagc cttgctaata atgaggaggt tagtttatgt atagtagact gaatctaaaa
      661 tagtacgaaa caattgctaa aacatttata gaaattaatt ttactttccc aatcgatttg
      721 ttctcatctt atttcaatcc gctatatatt atggtatcga atcttcatca gaatgataaa
      781 attaatcaat taatatctga ttacaaacag aatatgaaag ctttttatat cactattgaa
      841 aaatttatac gagatgatga aagccttaag tgttatttta caaaggttat ttcaagtcgt
      901 tccaaggtaa caagtctaga tcagattgaa gctgataaaa cgatacaaag aaaatattca
      961 agtgagctaa aaaaatttat tggattttat aatgagatta tttgtgagga aaatagtttc
     1021 ctacatgtac gaaagaggtg gtcgagttgg tttaggtagt cggtgcgtga gttgataatt
     1081 ctcagggtat ggacttcttt ttcatgaatg aggtaaaaga gcaggtattg tttagagaca
     1141 atcattctga gcatattttc tggatagagg gagtatccga ttttatgatc aaagttaata
     1201 ccgccctctg gtgagaagat gagtaggttg gtaatttaaa ctattaaaca gaatttttga
     1261 ttaaaagtat tatttcatga gagaaatcct aatttcacaa tctataggca aacgcttgca
     1321 tttcgttttt tattggacta taataggttg gtataaagcc ttctgtagta ataaaatgta
     1381 gaaggtgtag aaagtaagga tttagaatat ttgtagttaa aaacacaatg ttgctattcc
     1441 ttacgatagg gagatagata tggcaatgat agaagtggaa catcttcaga aacattttgt
     1501 gaagattgtt aaggaaccgg gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa
     1561 gcagaccttt gaagcggtca aggatttgac ctttgaggtt ccaaaagggc agattttagg
     1621 atttatcggg gcaaatggtg ctgggaagtc gacaaccatt aaaatgctga caggaatttt
     1681 gaaaccaaca tctggttttt gtcggattaa cggcaagatt ccccaggaca atcggcaaga
     1741 ttatgtcaaa gatattggcg tagtctttgg acaacgcacc cagctatggt gggatttggc
     1801 tctgcaagag acctacactg tcttaaaaga gatttatgat gtgccaaact cgctctttca
     1861 taagcgtatg gactttttga atgaagtctt ggatttgaag gactttatca aggatcccgt
     1921 gcggactctt tcactgggac aacggatgcg agcggatatt gcggcctcct tgctccacaa
     1981 tcccaaggtt ctttttttag atgagccgac cattggtttg gacgtttcgg ttaaggataa
     2041 tattcgtcgg gcaattactc agatcaatca agaggaagaa actaccattc ttttgaccac
     2101 tcacgatttg agtgatattg agcaactttg tgatcggatt ttcatgattg acaaggggca
     2161 aaagattttt gatggaacgg tgagccaact caaggagacc tttggtaaga tgaagactct
     2221 ctcttttgaa ctgctaccag gtcaaagtca tctcgtctct cactatgaag gtctgtctga
     2281 tatgaccatt gatagacaag gaaacagcct caacattgaa tttgatagtt ctcgctacca
     2341 gtcagctgac attatcaagc aaaccctatc tgattttgaa atccgcgatt tgaagatggt
     2401 ggatacggat attgaggata ttatccgtcg cttctaccga aaggagctct aggatgatca
     2461 aattgtggag acgttataaa ccctttatca atgcaggggt tcaggagttg attacttacc
     2521 gagtcaactt tattctctat cggattggcg atgtcatggg ggcttttgtg gccttttatc
     2581 tctggaaggc tgtctttgat tcttcgcaag agtctttgat tcagggcttc agtatggcgg
     2641 atatcaccct ctacatcatc atgagttttg tgaccaatct tctgactaga tccgattcgt
     2701 cctttatgat tggggaggag gtcaaggatg gctccattat catgcgtttg ttgcgaccag
     2761 tgcattttgc ggcctcctat cttttcaccg agcttggttc caagtggttg atttttatca
     2821 gcgttggcct tccattttta agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta
     2881 ttgtagaggt gctaggatta actgtccttt atctttttag cttaacgctc gcctatctga
     2941 ttaacttttt ctttaatatt tgctttggat tttcagcctt tgtgtttaaa aatctttggg
     3001 gttccaacct acttaagact tccatagtgg cttttatgtc ggggagtttg attcccttgg
     3061 cattctttcc aaaggttgtt tcagatattc tctccttttt gcctttttcg tccttgattt
     3121 atactccagt tatgatcatt gttggaaaat acgatgccag tcagattctt caggcactcc
     3181 ttttgcagtt cttctggctc ttagtgatgg tgggattgtc tcagttaatt tggaaacggg
     3241 tccagtcctt tatcaccatt caaggaggtt agtatgaaaa aatatcaacg aatgcatctg
     3301 atttttatca gacaatacat caaacaaatc atggaatata aggtggattt tgtggttggt
     3361 gtcttgggag tctttctggc tcaaggcttg aatctcttgt ttctcaatgt catctttcaa
     3421 catattccat tcctagaagg ctggaccttt caagagatag ctttcattta tggattttcc
     3481 ttgattccca agggaatgga ccatctcttt tttgacaatc tctgggcact agggcaacgc
     3541 ctagtccgaa aaggagagtt tgacaagtat ctgactcgtc ccatcaatcc tctctttcac
     3601 atcctagttg aaacctttca gattgatgcc ttgggtgaac tcttagtcgg tggtatttta
     3661 ttgggaacaa cagtgaccag cattgtttgg actcttccaa aattcctgct tttcctagtt
     3721 tgtattcctt ttgcgacctt gatttatact tctcttaaaa tcgcaacagc cagtatcgcc
     3781 ttttggacta agcagtcagg cgccatgatt tacatcttct atatgttcaa tgactttgct
     3841 aagtatccga tttctattta caattctctt cttcgttggt tgattagctt tatcgtgcct
     3901 ttcgccttta cagcctacta tccagctagc tatttcttac aggaaaagga tgtgttcttt
     3961 aacgtaggag gtttgatgtt gatttctctg gttttctttg ttatttccct taaactttgg
     4021 gataagggct tagattccta cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat
     4081 caagaaagga acttatgatg tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc
     4141 agttgtcgtt gaggttttga aggatttgcc agaatggttt ggaatcccag aaagcacaca
     4201 agcctatata gaaggaacca cgacactgca agtttggacc gcctatcagg agagtgattt
     4261 gactggattt gtaaggttat cctattcgag tgaagattgt gcagagattg attgtctcgg
     4321 cgtaaaaaag cttatcaagg tagaaaaatt gggagccaat tgcttgctac tttagagagt
     4381 gaagctcgta aaaaagttgg ttatctgcag gtcaaaacag tggcagaagg ttctaataaa
     4441 gattatgatc gaacaaatga cttttatcga ggtcttggct ttaaaaagtt agagattttt
     4501 tctcagctat ggaatccgta aaatccttgt cagattttga ttaaaaagct tgaataatat
     4561 tacttgacat ctattctcag agtgccatac tgtaagtgta atcgccgatt tagctcagtt
     4621 ggtagagcaa ggcactcgta aagcctaggt tataggtaga taaacgactg aggagttgaa
     4681 aaaatagata ggtagaagat aaccgttaag ccttattctt agcggttatt tatattgttt
     4741 aatagcgctg atatttcatc aattatgcct gttttcgtgt ttctggtagt tgttcaagtt
     4801 tattgctact atttttgatg gtatgaatgt gcttataatg tatcccggtt aacgaaagtt
     4861 ttggacttat actcat
//
LOCUS       DAVEHY010000071         4613 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVEHY010000071 DAVEHY010000000
VERSION     DAVEHY010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.071"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..1542)
                     /locus_tag="VUZ44_002119"
     CDS             complement(<1..1542)
                     /locus_tag="VUZ44_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEU0320960.1"
                     /translation="MFKVLRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNGTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASINAAVFSGNMIVNGAPAINASLNIA
                     KSETKVYTGTGKDSFYNIPIYYQLTVTNDGSKLTFTYTVTYVNPTTKILGNLSNMRPG
                     YSIYNTGTSTQTMLTLGSGLGIPSGVKNSITDKNGRQVRYYNTSTMTKRGSGYTWVNG
                     AQMNGWYAKKEYGLTSSWTVPITGTDTSFTFTPYAAKTDRIGINYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASASASTSASASASTSASESASTSASASASTSA
                     SASASTSASVSASTSASASASTSASASASTSASASASTSASASASTSASESASTSASV
                     SASTSA"
     gene            complement(1540..1653)
                     /locus_tag="VUZ44_002120"
                     /pseudo
     CDS             complement(1540..1653)
                     /locus_tag="VUZ44_002120"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(1900..2361)
                     /locus_tag="VUZ44_002121"
     CDS             complement(1900..2361)
                     /locus_tag="VUZ44_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320961.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     DRYLYRPYAGAPRGEKVYGKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2328..2429)
                     /locus_tag="VUZ44_002122"
     CDS             complement(2328..2429)
                     /locus_tag="VUZ44_002122"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320962.1"
                     /translation="MKGGHRHVEAAKVFDVGVRTLFTWEKKDVNKGT"
     gene            2740..3120
                     /locus_tag="VUZ44_002123"
     CDS             2740..3120
                     /locus_tag="VUZ44_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU0320963.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3220..3441
                     /locus_tag="VUZ44_002124"
     CDS             3220..3441
                     /locus_tag="VUZ44_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU0320964.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3458..3772
                     /gene="trxA"
                     /locus_tag="VUZ44_002125"
     CDS             3458..3772
                     /gene="trxA"
                     /locus_tag="VUZ44_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU0320965.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4077..4610
                     /gene="queF"
                     /locus_tag="VUZ44_002126"
     CDS             4077..4610
                     /gene="queF"
                     /locus_tag="VUZ44_002126"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU0320966.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         1375 a          967 c          886 g         1385 t
ORIGIN      
        1 agcacttgtt gatgctgaga ctgacgcact cgttgatgcc gattcagacg ctgaggtgct
       61 tgctgaggct gacgcactcg ttgatgctga agctgaagca cttgtcgacg ctgaagccga
      121 cgcacttgtg cttgctgaag ctgaagcact tgtgcttgct gagactgatg cactggttga
      181 cgctgaagcc gaggcactgg tacttgctga ggctgaagca ctcgttgatg cggattcaga
      241 cgcacttgtt gatgctgaag ccgacgcact cgttgatgct gaagccgacg cacttgttga
      301 tgctgaagct gaggcgcttt gactagcact tactgagagt gacttagact gtgaaagtga
      361 ctgactggtc gtgctagatt caactacctt tcctctaccc ttgaagtagt taattccaat
      421 tctatctgtt ttagcagcgt aaggggtaaa tgtaaaggat gtatccgttc cagtaattgg
      481 tacagtccaa gatgatgtta atccatattc tttcttagca taccaaccat tcatttgggc
      541 accatttacc caagtatacc cactaccccg cttcgtcatt gtagatgtat tatagtatcg
      601 aacctgtcta ccatttttgt cagtaatgga gttctttaca cctgaaggga taccaagacc
      661 actgccaagg gttaacattg tttgtgttga agtacctgta ttatagatag aatacccagg
      721 acgcatattt gaaagattac caagaatctt tgttgtagga ttcacatacg taaccgtata
      781 ggtaaaggtc aattttgaac catcatttgt cactgtcaat tgatagtaaa ttggaatatt
      841 ataaaatgaa tctttacctg tacccgtgta aacttttgtc tcacttttag caatgtttag
      901 acttgcatta attgcaggag cgccatttac aatcatattg ccagaaaaaa cagcagcatt
      961 tatagaagcc agcaattgct cgatggaatc cactgaacgc ttgcgtcgct tagcataaga
     1021 ttggagattg acatttgtaa ctgatgctac ataatcacta gctggtttct tacgatcttc
     1081 ttcgaccttc ttagcagttg cttctgtagc ggcagctgtt tgtgaaccta ccacagtaga
     1141 tgatgcagag atacttgtcg aagccgatgt acttgctgat tctgatgcac ttgtactcgc
     1201 tgaggtcgaa gcgctggttg aggctgactc agatgcagat gtacttgccg actctgaagc
     1261 tgacaaacta gttgaactcg ctgaattact tgtagatatc gtacctagaa ctactgtacc
     1321 atttgttgcc aaagcatccg ttttctctac agttttttca agtactgctg actcatttgt
     1381 aaataccttc gtttgagttg caacggttcc acttatgaca gttcccgcag caactatccc
     1441 cttgaggata tcaagcccag taattgaatg acttacttta tcttctaccg tttcggtcat
     1501 gacctgagta gtatcaacac cacctcgcaa gaccttaaac aagccaaaaa gagaagtcga
     1561 ggcccgtagc caatgcttcc ctgatttgat taatttgaac cgagttactc ggtctgtttc
     1621 tctatattca cccttctgac gtctaaaaaa tattttgaaa tttcctttcg agtattattt
     1681 tcatgtatgg atataaataa attaccatac tataattata gaatagggaa cccaaaatag
     1741 caagaaactt gaggtatttt tgctaaaaaa aaaaaagcat tttactattt tgtatatata
     1801 tatatatatt ataagataag ttttttataa agacacgcaa atgagtataa atcagctaat
     1861 ttttggttta tattcctatt tttatgcata attattcttt cattctctaa tttgtgaatc
     1921 aatatatctg attagaaaac taccattgag tttttgctcc acctcattag tccgctcaaa
     1981 acgccgtccg ctaatcttgc catagacttt ctcccctcta ggagcccctg cataaggacg
     2041 atagaggtag cggtcgattc ccgtttcgtc aatatatagg actggtaaat cttttaggtt
     2101 atccaaaata tcaagaaact cagaaacttt ctcaggcttt tgttccctaa aactggtcgt
     2161 cttttttaaa atgaccttaa tctgctttaa aactgcccat acggagggca aagcacaatc
     2221 aaaacgggcc gcaatttccc gtaaaaaagc gtctggatga gcctctacaa aggctttcaa
     2281 ttcttctaaa gggatcttac gctttttgac gactcgcttt ttccgctcta agttcccttg
     2341 tttacgtctt tcttttccca cgtgaagaga gttctgacgc cgacatcaaa aactttggcc
     2401 gcctcgacat gtctgtgccc tcctttaatg gaatctaatg ctccttgttt aaaatcagta
     2461 ctatatgcat agctttatta gaccatgctt attttaaact aagcaactat agatagagaa
     2521 atgaaataaa atctgaattc gaatgtgata aggagttaga aattgaaaca ataggattcc
     2581 cccattattc acacaaaaat aaaaccacta aaaaacagag cttgccagca ttcttgaaaa
     2641 gtagtataat tattgcatgc gcaatcatct tatgacgcaa agactgcccg ttaatggact
     2701 ttcttctata attatgactc taaaaagaaa ggagacacta tgacctattt ggaaaaatgg
     2761 tttgacttca atcggcgtca gaaagaaatt gaaagtctct tggaagagac cattgcccaa
     2821 cagagcgagc aaagtctgac cttgaaagag ttctacctgc tctactatct ggacttggct
     2881 gaagaaaaat ctctacgcca gattgatctg ccagataagc ttcatctgag tccaagcgca
     2941 gtttctagga tggtggctcg cttggaagct aaaaattgcg gtctactcag tcgcatgtgt
     3001 tgccatcaag atagacgctc tagttttatc tgcctgacaa atgatgggca aaagacactg
     3061 gcctcgctac aaaagactgt cgaagaaagc ttggaagcag gtttggattt cttgatttaa
     3121 gatgatttta aaaaaaagtt gcgtgcgcaa tcatttttct tgacattctc ttttataagg
     3181 agtaaaataa agttagcatt aaacaaagga gttttaaaca tgattgaaat tacctatata
     3241 gatgccagca agaacgaaag aactgtgact ttcgagtctt atgaagactt tgaacgttcg
     3301 caacaagctt gccttatcgg cgtcgcagac tactaccctg tccaaaaatt aacttacaag
     3361 ggtcataatt tggactacca tgggacttat ggagatatct tcttctatct catgaaacaa
     3421 gatttaagcc aatataacta aaaaaaggag aaatacaatg gcaaaagcaa ttacagatgc
     3481 aacattcgaa caagaaacaa aagacggttt ggtcttagta gacttctggg caacttggtg
     3541 tggtccatgt cgtatgcaag gtccaatctt ggacaaattg tctgaagaac tttcagaaga
     3601 tgtcttgaaa atcgttaaaa tggacgttga tgaaaatcca aatacagctc gtgcttttgg
     3661 aatcatgtct attccaactc ttctcttcaa aaaagacggc caagttgtca aacaagttgc
     3721 aggtgttcac acagcagaac aaatcaaggc catcattgct gaattgagct aatcaaacga
     3781 gagaccaagt actttctttg gtctcttttt tcttgccctt tgccattttt caaaaaatat
     3841 gctagactat agtagattga aactagaata gtacacctct acttctaaaa cattgttaga
     3901 aatcgattta actgtcctga tcgatttgtc ctgttcttat ttcattttac tatataagta
     3961 gaatattacg acgtttggga tatgccatcg ctaaaaaaac tcgatttggt attttttagc
     4021 tccctaatgg gagctttttg cgtgctctga acatttccca ttttggaagg agtactatga
     4081 aacatcaatc agccttggtc gtctttagtg gtggtcaaga ttcaacaacc tgccttttct
     4141 gggccatgca acactatgaa acagtcgaag ctgtcacctt tgcctacggc caacgtcatc
     4201 acctcgaaat tcaaattact agagaaatcg ctaaggaaca gggcattcgt caccatatcc
     4261 tcgatatgtc tctgctggga caaatcactg ctcagccaga ctttgcgacg attcatattt
     4321 cctacattcc tgacaagctc tgtgtcgagt caaaatccct caaactatat ctatttagct
     4381 accgaaacca cggagatttc cacgaaaact gtatcaacac catcgggaaa gacttggtca
     4441 acttgctaga ccctcgctat ttagaagtct ggggaaaatt cactccgcgc ggtggcattt
     4501 caatcgaccc ctactacaac tacggtaagc aaggaactaa gtatgagggc ttggcagaac
     4561 aacgcctctt ccaacacgac ctttatccag agaaaattga caaccgctaa agt
//
LOCUS       DAVEHY010000072         4013 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVEHY010000072 DAVEHY010000000
VERSION     DAVEHY010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.072"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            24..1307
                     /locus_tag="VUZ44_002127"
     CDS             24..1307
                     /locus_tag="VUZ44_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU0320967.1"
                     /translation="MVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKE
                     KIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLF
                     YILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLAEQQRIIEAIESALEKVDE
                     YAESYNRLEQLDKKFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFE
                     EGKIKKKDLDISIVSQGDDSSYYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIP
                     IYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIY
                     HENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELL
                     TKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            1364..2161
                     /gene="psrA"
                     /locus_tag="VUZ44_002128"
     CDS             1364..2161
                     /gene="psrA"
                     /locus_tag="VUZ44_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU0320968.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            2172..2780
                     /locus_tag="VUZ44_002129"
     CDS             2172..2780
                     /locus_tag="VUZ44_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU0320969.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(2728..4005)
                     /locus_tag="VUZ44_002130"
     CDS             complement(2728..4005)
                     /locus_tag="VUZ44_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU0320970.1"
                     /translation="MRIKSIYWNFGQNKPEKSFRYIDTSSIDRKKNIINYKNLQYLSP
                     EQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIASTAFIVLDTLLNETYLKY
                     YLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQRIVEAIESALEKVDEY
                     AESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEE
                     GKIKKKDLDISIVSQGDDNSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGV
                     RIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDK
                     DYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTT
                     LSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
BASE COUNT         1397 a          596 c          662 g         1358 t
ORIGIN      
        1 gggagtgggt gaggttttct acattggttg aaattgtcag aggtggctct ccacgaccaa
       61 tcaaagatta tcttacttct gaagtagatg gaataaattg gataaaaata ggtgatactg
      121 aaaagggtga aaagtatata aataatgtta aagaaaaaat caaaaaatca gggcttaaca
      181 aaactagatt tgtaaaaaaa ggtacatttt tgttaactaa ttctatgagt tttggtagac
      241 cttatatttt gaatgttgat ggtgcaatac acgatggatg gttggctatt tcgaactatg
      301 aaaactcatt aaataaagat tacctattct atattctttc atcaaatgta gtttattctc
      361 aatttctatc tctaattagt ggagctgttg tgaaaaactt gaatagtgat aaagttgctt
      421 ctattcttat ccctctccct ccgctagctg aacaacaacg cataatagaa gcaatcgaat
      481 cagctttaga aaaagtagat gaatatgctg aaagttataa tagactagaa cagctagata
      541 aaaaatttcc agataaacta aaaaaatcta ttcttcaata tgctatgcaa ggaaaattag
      601 ttgaacaaga cccaaatgat gaatcagtcg aagttttact tgaaaaaata cgagcagaaa
      661 aacaaaaact ctttgaagaa ggcaagatta aaaagaaaga tttggacatt tctattgttt
      721 cccaaggaga tgatagctct tattatgagg aagtaccttg tgaaatacca gaaagttggg
      781 aatgggtgag gttaaacgat ataacctcct acattcaaag agggaagtct ccaaaatatt
      841 caaatattcc tatataccct gtgattgctc agaaatgtaa tcaatggtct ggcttttcta
      901 ttgacttagc aagatttatt gatcccgaaa cagttcatag ttaccagaaa gaaagattac
      961 taagagatgg tgatttaatg tggaattcaa caggtctagg tacgttagga cgattagcta
     1021 tttaccatga aaataaaaat ccttatggct gggctgttgc agatagccat gttacagtta
     1081 taagagtctt atcgggagtt attaattgcc atttcatcta taattttctt tcctctccta
     1141 ttgttcagtc agttattgaa gaaaaagcgt cgggtagtac aaaacaaaaa gaattattaa
     1201 cgaaaactat aaaagaatat ttaatccccc tcccacccct tcctgaacaa tccagaatcg
     1261 ttgataaaat cgaacaattt ttcgcccata ttgacgcact aatttagtat aatagtttta
     1321 cgtgcggtgg aatttctatc aaacataaga taggagtttt acgttgaaag attttgaatt
     1381 acatttgaag aaagctggtt tagctgaaaa tactgtgcgt tcgtaccttt atggtgttcg
     1441 atttttcttg gagaattacg aactcaaaat ggaagattta tttgaataca aaggatattt
     1501 attagacaat tttaaaccta aaactgtcaa tttgcgacta caaggagtaa ataaatatct
     1561 ggcttttatt ggtcatgatg atttgaaatt aaaatttgtc aaagtacagc aaaaaccgtt
     1621 tttagaagat gtcattagcc atgctgatta cctttttctt aaacgtagtt tgaaaaaaga
     1681 tggtatttta aaatggcatt ttgtcgtttg gtttttaggt gcaactgggg ctcgtgtaag
     1741 tgaacttatt aaactaaaag tagagcatgt agaaatcggt tattttgaca tttactcaaa
     1801 aggtggtaaa attcgtagac tgtacattcc taaaaaatta agaaatagtt gtcttagttg
     1861 gttagaatca gaaaatcgcc gaagtggtta tttatttttg aataaattta acgaaccaat
     1921 tacagcaaga ggagttgctc aacagttaaa aaattatgct gataaataca aaatgaatcc
     1981 taaagtaatt taccctcatt cttttaggca tttatttgct aagaattttt tagcgaagta
     2041 taatgatatt gccttgcttg cagatttgat gggacacgaa agtatagaaa ctactcgaat
     2101 ttatctaagg aaaacagcta ctgaacaaca aaatattgta gataaaattg ttaattggta
     2161 aaaaataaca ggtggtcaaa ctgactacct gctatttttg tgattatggc tcttattatg
     2221 ggaacaaaga cgaaacaacc tcttatccta tatatgaaat cccagaagca tggagatata
     2281 ttaaatttgc tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta
     2341 ctttttgggg aactgaaata ccttgggtat ctatatcaga tatgcctata tctggttatg
     2401 taactaatac gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt
     2461 cacctaaagg aactttatta atgagtttta aattatctat tggaaaagtt gccatattgg
     2521 atattcctgc cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa
     2581 atattatcag agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa
     2641 aagatgctat caaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta
     2701 tttctaatca tgaagagatg aaaagaatca tttccaaagt tgatttactt tttcaaaaag
     2761 tttctcaact ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag
     2821 ctcgctcagt gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc
     2881 tttcaattgt ttataaaata acggagagga caagttaaat aatagaaatt ttgaaataat
     2941 ctctgaactt tcgaatggtg ttaattggaa aataaatcca ccagccacaa caccatcata
     3001 gtctttatcg attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat
     3061 tagctgatta tgttttaaat aaacttgctc agaggagatg aattgtgtat caatgtagta
     3121 atcgttatcc aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaac
     3181 acctttatta ttaatgctta aatcgccctt cttgtaagaa agacctgtat tcattgaaaa
     3241 aatatctttt atttttataa caacccaatt cataggtata ttcccataat aagagttatc
     3301 atctccttgg gaaacaatag aaatgtccaa atctttcttt ttaatcttgc cttcttcaaa
     3361 gagtttttgt ttttctgctc gtattttttc aagtaaaact tcgactgatt catcatttgg
     3421 gtcttgttca actaattttc cttgcatagc atattgaaga atagattttt ttagtttatc
     3481 tggaaattct ttatctagct gttctagtct attataactt tcagcatatt catctacttt
     3541 ttctaaagct gattcgattg cttctactat tcgttgttgt tcggatagtg gggggagagc
     3601 aattaataat agattaaaat tataatcatt gattgcagga taacttgttc cagtagattt
     3661 attattaaca cgattgataa aattatctga taataaataa tatttcaaat atgtttcgtt
     3721 aagtaaagta tccaaaacaa taaatgctgt actagctatc aaatactctt taagttctct
     3781 aactacagca atatttttta gatatggtct aactgttgaa aataagacac tattctgcga
     3841 aactaatttt ctagcacggg aaggcgcttg ttcaggtgaa agatattgta gatttttgta
     3901 gttgattatg ttcttttttc tatcaatact agacgtatct atatacctaa aggatttctc
     3961 tggcttattt tgcccaaaat tccaataaat tgattttatc ctcacccact ccc
//
LOCUS       DAVEHY010000073         3760 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVEHY010000073 DAVEHY010000000
VERSION     DAVEHY010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.073"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            198..2648
                     /gene="phtA"
                     /locus_tag="VUZ44_002131"
     CDS             198..2648
                     /gene="phtA"
                     /locus_tag="VUZ44_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU0320971.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQQTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            2806..>3760
                     /locus_tag="VUZ44_002132"
     CDS             2806..>3760
                     /locus_tag="VUZ44_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU0320972.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QAAQKTENLTPDEVSKKEGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITS"
BASE COUNT         1328 a          701 c          763 g          968 t
ORIGIN      
        1 ttcaagaaaa tctttcttat agaaagtcca accttgaaaa agtagtggtc agaacaaaaa
       61 atacttaaat ggttcataaa attcttgaca agttggagat ttaggagtaa actattaacc
      121 agttaagtaa tagagaggag tttctgcaat ttagaaatga attgcaacta gaaatatcaa
      181 atagaaagag agtttcgatg aaaattaata agaaatacct tgttggttct gcggcagctt
      241 tgattttaag tgtttgttct tacgagttgg gactgtatca agctagaacg gttaaggaaa
      301 ataatcgtgt ttcctatata gatggaaaac aagcgacgca aaaaacggag aatttgactc
      361 ctgatgaggt tagcaagcgt gaaggaatca atgctgagca aatcgtcatc aagataacag
      421 accaaggcta tgtgacttca catggggacc actatcatta ttacaatggg aaggttcctt
      481 atgacgctat catcagtgaa gaattgctga tgaaggatcc aaactaccag ctaaaagacg
      541 aggatattat cagtgaaatc aagggtggtt atgttatcaa ggtagatgga aaatactatg
      601 tttaccttaa ggatgctgcc cacgcggata acgtccgtac aaaagaggaa atcaatcgac
      661 aaaaacaaga gcatagtcaa catcgtgaag gtgggactcc aagaaacgat ggtgctgttg
      721 ccttggcacg ttcgcaagga cgctatacta cagatgatgg ttatatcttt aatgcttctg
      781 atatcataga ggatactggt gatgcttata tcgttcctca tggagatcat taccattaca
      841 ttcctaagaa tgagttatca gctagcgagt tagctgctgc agaagccttc ctatctggtc
      901 ggggaaatct gtcaaattca agaacctatc gccgacaaaa tagcgataac acttcaagaa
      961 caaactgggt accttctgta agcaatccag gaactacaaa tactaacaca agcaacaaca
     1021 gcaacactaa cagtcaagca agtcaaagta atgacattga tagtctcttg aaacagctct
     1081 acaaactgcc tttgagtcaa cgccatgtag aatctgatgg ccttattttc gacccagcgc
     1141 aaatcacaag tcgaacagct agaggtgttg cagtgccaca cggagatcat taccacttca
     1201 tcccttactc tcaaatgtct gaattggaag aacgaatcgc tcgtattatt ccccttcgtt
     1261 atcgttcaaa ccattgggta ccggattcaa ggccagaaca accaagtcca caacagactc
     1321 cggaacctag tccaggcccg caacctgcac caaatcttaa aatagattca aattcttctt
     1381 tggttagtca gctggtacga aaagttgggg aaggatatgt attcgaagaa aagggcatct
     1441 ctcgttatgt ctttgcgaaa gatttaccat ctgaaactgt taaaaatctt gaaagcaagt
     1501 tatcaaaaca agagagtgtt tcacacactt taactgctaa aaaagaaaat gttgctcctc
     1561 gtgaccaaga attttatgat aaagcatata atctgttaac tgaggctcat aaagccttgt
     1621 ttgaaaataa gggtcgtaat tctgatttcc aagccttaga caaattatta gaacgcttga
     1681 atgatgaatc gactaataaa gaaaaattgg tagatgattt attggcattc ctagcaccaa
     1741 ttacccatcc agagcgactt ggcaagccaa attctcaaat tgagtatact gaagacgaag
     1801 ttcgtattgc tcaattagct gataagtata caacgtcaga tggttacatt tttgatgaac
     1861 atgatataat cagtgatgaa ggagatgcat atgtaacgcc tcatatgggc catagtcact
     1921 ggattggaaa agacagcctt tctgataagg aaaaagttgc agctcaagcc tatactaaag
     1981 aaaaaggtat cctacctcca tctccagacg cagatgttaa agcaaatcca actggagata
     2041 gtgcagcagc tatttacaat cgtgtgaaag gggaaaaacg aattccactc gttcgacttc
     2101 catatatggt tgagcataca gttgaggtta aaaacggtaa tttgattatt cctcataagg
     2161 atcattacca taatattaaa tttgcttggt ttgatgatca cacatacaaa gctccaaatg
     2221 gctatacctt ggaagatttg tttgcgacga ttaagtacta cgtagaacac cctgacgaac
     2281 gtccacattc taatgatgga tggggcaatg ccagtgagca tgtgttaggc aagaaagacc
     2341 acagtgaaga tccaaataag aacttcaaag cggatgaaga gccagtagag gaaacacctg
     2401 ctgagccaga agtccctcaa gtagagactg aaaaagtaga agcccaactc aaagaagcag
     2461 aagttttgct tgcgaaagta acggattcta gtctgaaagc caatgcaaca gaaactctag
     2521 ctggtttacg aaataatttg actcttcaaa ttatggataa caatagtatc atggcagaag
     2581 cagaaaaatt acttgcgttg ttaaaaggaa gtaatccttc atctgtaagt aaggaaaaaa
     2641 taaactaatg aaaaatgaaa gtctcgataa agaggctttc atttttatta tgtatatatg
     2701 taaaattctt gacaagcaat attaaaaaga gtaaactatt aactagttaa ttaaccggtt
     2761 tattacttta tagtgaatca aatatacttg agaaaagagg aaagaatgaa aatcaataaa
     2821 aaatatctag ctgggtcagt agctacactt gttttaagtg tctgtgctta tgaactaggt
     2881 ttgcatcaag ctcaaactgt aaaagaaaat aatcgtgttt cctatataga tggtaaacaa
     2941 gcagcacaaa aaacggagaa tctgactcct gatgaggtca gtaaaaaaga aggtatcaat
     3001 gccgaacaaa tcgtcatcaa gataacagac caaggctatg tgacttcaca tggggaccac
     3061 tatcattatt acaatgggaa ggttccttat gacgctatca tcagtgaaga attgctgatg
     3121 aaggatccaa actaccagct aaaagacgag gatattatca gtgaaatcaa gggtggttat
     3181 gttatcaagg tagatggaaa atactatgtt taccttaagg atgctgccca cgcggataat
     3241 gtccgtacaa aagaagaaat caatcggcaa aaacaagaac atagtcagca tcgtgaagga
     3301 gggacttcag caaacgatgg tgcggtagcc tttgcacgtt cacagggacg ctacaccaca
     3361 gatgatgggt atatcttcaa tgcatctgat atcattgagg acacgggtga tgcttatatc
     3421 gttcctcacg gcgaccatta ccattacatt cctaagaatg agttatcagc tagcgagttg
     3481 gctgctgcag aagccttcct atctggtcgg gaaaatctgt caaatttaag aacctatcgc
     3541 cgacaaaata gcgataacac tccaagaaca aactgggtac cttctgtaag caatccagga
     3601 actacaaata ctaacacaag caacaacagc aacactaaca gtcaagcaag tcaaagtaat
     3661 gacattgata gtctcttgaa acagctctac aaactgcctt tgagtcaacg ccatgtagaa
     3721 tctgatggcc ttattttcga cccagcgcaa atcacaagtc
//
LOCUS       DAVEHY010000074         3414 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVEHY010000074 DAVEHY010000000
VERSION     DAVEHY010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.074"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..270
                     /locus_tag="VUZ44_002133"
     CDS             <1..270
                     /locus_tag="VUZ44_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320973.1"
                     /translation="VTHYKYYRAENSHLIYADYFEMKLQKLLKDDTKVFEKSTFKFVE
                     GYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(625..1158)
                     /locus_tag="VUZ44_002134"
     CDS             complement(625..1158)
                     /locus_tag="VUZ44_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU0320974.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1247..2023)
                     /gene="recX"
                     /locus_tag="VUZ44_002135"
     CDS             complement(1247..2023)
                     /gene="recX"
                     /locus_tag="VUZ44_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU0320975.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2061..>3414
                     /gene="rlmD"
                     /locus_tag="VUZ44_002136"
     CDS             2061..>3414
                     /gene="rlmD"
                     /locus_tag="VUZ44_002136"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU0320976.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1118 a          581 c          595 g         1120 t
ORIGIN      
        1 gttacccact acaaatatta tagagccgaa aattcacatc taatatatgc agactacttt
       61 gaaatgaaat tacaaaaatt attaaaagat gacacaaaag tttttgaaaa atctacattc
      121 aaatttgtag aaggatataa aatatacctg acagaatcta aagaatctgg aattaaacaa
      181 atggacaatg tcataaaata ttttgagttt attgaatcta aaagtattgc tttatatttt
      241 caaaaacgat taaatgagct gatagattaa atatcatttt ctctgttaag atattgtttt
      301 taaaatattg tactaaatga ttgatgctat gtggaaatac aaaaaaatgt ttttgatacg
      361 aagttgacct gtatttttta tactaatcat tttcgtattt tttgtattaa acgatataag
      421 tttgttgtaa acttacaagg aataaagaca ttaaaaaata acagtatatc tatttgtttt
      481 atatatttta cgaattttgc ataaatctct ttctagtaat gtgttgtaac tctgctataa
      541 tagatttatt cctttttgtg tttacacaat ttattttata ctaccaaaaa aaggtcagga
      601 ttttgttcct gacctttgac aactttaccg attctttagt tctacatagc gcttgtacca
      661 aatgtttaca taggcttctg agaaaggacc acgtccattg ttaatccaat caacaagaat
      721 tttgacatgt tcttttaaaa tatagtccaa gtcatcagaa taattcattt tgcgtttgtg
      781 acgctcgtac tcttcaacgt ccaagagacg tttttcccca tctgtaaaaa ttttaacatc
      841 caaatcgtaa tcaatatact tcagtgcttc ttcatccaga tagtaggggc tagccatatt
      901 gcaatagtaa gaagttccat tatcacgaat catggcaatg atattaaacc aatatttctt
      961 gtgaaagtaa acaatagccg gttctcgagt gacccaacga cgaccatcac tttcggtaac
     1021 aagtgtatga tcgttgacac caataatggc gttttctgtt gtttttagta ccatggtgtc
     1081 ccgccaagtt cggtggagac tcccatcatg cttataactt tgaattgtaa taaagtcgcc
     1141 ttcttttgga agcttcataa ctaaccaact ttctacaatt tataagttta tcatttacta
     1201 ttgtaccata aaattaccta aaatctgtga atttcacttg gaaatattaa agatattctc
     1261 taagagcgct tgctatatcc gaaaaatcgt agccctttcg tgctaaaact tgagttaaac
     1321 gctgcttcag ttcgtatcct tcatactttc gagcatactt agtatattgc ttatcaagtt
     1381 ccttgaagat gagttcttga gtcgtttctt ggtcaacttg gctatctaag tcgtcaaagg
     1441 caattttagc atcagaataa gagaagccct tgttagtcaa gttctggata atcttatctt
     1501 gcagggcacg agctggaagt tttccctcat attttttcaa tagtttattg gctacacgtt
     1561 gagcaacttc cgaaaaatca aaatcattca agatttcttc tatagtagat tttgaaattc
     1621 ctttttgtgc taatttctga gtcagtacat aaggtccctt gtctcctgaa agttgattgg
     1681 cattgatgat agcataagcg tactgaccat cattaatcca cttatcttct ttaagattag
     1741 caataacttg agaaacgatg tttttatcaa tatcgtattt tttcagatat tctctgactt
     1801 ctttttcagt gcgtgcttta aaggataagt ggtagagggc cagattctta ccataagaaa
     1861 attgagcaaa gtcttgaatc tctttcaatt cctcttcgct tatcacctta tctctcgata
     1921 acataaaacg aacaattgta tcttcggtga tatagcattt gtcgccatta tcaagctcca
     1981 tcagatagag tctttttttc ttttcaagtt ttgtgatttt catagctcta ttataactca
     2041 aaatgtgata agataggggt atgaatctga aagtgaaaca aaaaatacca ttaaaaatca
     2101 agcgcatggg aattaacggt gagggaatcg gcttttacca aaaaacatta gtctttgtac
     2161 caggagctct caaaggcgaa gatatctatt gtcagattac ttctattaga cgcaactttg
     2221 ttgaagcaaa attactgaag gtcaacaaga agtctaaatt tcgaattgtg ccatcttgta
     2281 ctatttataa tgaatgcgga ggctgccaaa tcatgcacct gcattatgat aagcagctgg
     2341 agttcaagac ggacttactt catcaagcgc tgaaaaaatt tgctcctgca ggatatgaaa
     2401 attatgaaat tcgtccaact attggaatgc aggaaccaaa atattacaga gctaagttac
     2461 aatttcagac ccgaaaattt aaaaatcagg tcaaggcggg cttatatgca caaaactctc
     2521 actatttagt agagttgaaa gactgcctgg tacaagataa ggaaacccaa gtgattgcta
     2581 atcgcttagc agaattactt acttatcacc agattccaat cacggatgag agaaaagttc
     2641 taggtgtccg tactattatg gtccgacgcg cgagaaagac cggacaggtt cagattatta
     2701 ttgttacaaa ccgccagctt aatttaactc aattggtaaa agagttggtt aaagatttcc
     2761 cagaagttgt gacagtagct gttaatacaa atacagctaa aaccagtgag atatatggtg
     2821 aaaagacaga gattatctgg gggcaagaga gtattcaaga aggtgtactc aattatgaat
     2881 tttcactatc ccctcgagct ttttatcaac taaatcctga gcaaacagaa gtcctctata
     2941 gcgaagcagt aaaagcgctg gatgttgata aagaagacca tttgattgac gcttattgtg
     3001 gagttggaac gattggattt gcctttgcaa agaaagtaaa aacactcaga ggtatggata
     3061 ttattccaga agctattgaa gatgccaagc gaaatgctaa aagaatggga tttgacaata
     3121 ctcattatga agctggaacg gcagaagaga ttattcctcg ttggtacaag gaaggctacc
     3181 gagcagatgc tttgattgtt gacccaccac gtacaggtct ggatgataag ttattagata
     3241 ctattcttac ttatgtacca gaaaaaatgg tttatatttc ttgtaatgtt tcgaccttgg
     3301 ctcgtgattt ggtacgctta gtagaagtct atgatcttca ttatatccag tcggtcgata
     3361 tgttcccaca tacagctcga actgaagctg ttgtaaaatt aataaaaaaa gttt
//
LOCUS       DAVEHY010000075         3163 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVEHY010000075 DAVEHY010000000
VERSION     DAVEHY010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3163
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.075"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            421..750
                     /locus_tag="VUZ44_002137"
     CDS             421..750
                     /locus_tag="VUZ44_002137"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320977.1"
                     /translation="MSISFRTNTSMMNIAYKNRDLSDEEFKEEAHQFRDKEIKILEEK
                     LKELNISCKVVGINSIKDMNEYKEIMENVNQAKEELKRIDELIAVRSSRIDFLEDKTL
                     RITGNQR"
     gene            1213..1689
                     /locus_tag="VUZ44_002138"
     CDS             1213..1689
                     /locus_tag="VUZ44_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320978.1"
                     /translation="MNKKFLKCGTLFLISCSILGSTIPAVTVFSDEVTITYNSENNSE
                     KNELYNQLSAEKKGQFDELVSNLNLSEQEQLDLLQQYKEEHPRRAKRGIKSAIIKKVA
                     RFLAAKVGQKSVVEITDYLFEWQDNLEAGAENYLVQYGWDRNIAHWTIKTVSFIFL"
     gene            2176..3138
                     /locus_tag="VUZ44_002139"
     CDS             2176..3138
                     /locus_tag="VUZ44_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEU0320979.1"
                     /translation="MEKWENQDKILLDKNKRGKDRNWRGRKLLSLKLADIFKELGYRE
                     TLIERVETCGDTLRFIRREDGSLRLYQAYFCKNKLCPMCNWRRSMKYSYQTSQIVDEA
                     IKEQPKGRFLFLTLTVKNVPGKELNATISQLTQSFDRLFRRAKVKKNLIGFLRSVEVT
                     HNQEEETYHPHIHVLMMVKSSYFSGAGDNYVSQEEWGRMWEQSLKVDYVPIVDIRSVK
                     EIGKGLKGAILETAKYPIKPIKLDVENKQVVGDLYNGLYRKRQLGYGGLFKEIRKRLQ
                     LSNVENGDLVYISDDNDEMSKGTKIVAIWNATKQNYFVKNKGWN"
BASE COUNT         1118 a          364 c          652 g         1029 t
ORIGIN      
        1 aaaaaaaaga gtaaaataga cttgattttt ttgagtttag atgtatattg aaggtgtgaa
       61 aattaaaaag atagctatgt ttttttctgg gtatacttgt tggggtattt attgttctat
      121 tttttagaaa ttattttgtt ttacttttgg aatatatttt tggttaaaaa gcaccctcta
      181 aaaagggtgc tttttgtgcg gttattcgca cgaaagttct ctgcaagagt tcctcggaag
      241 agcgtttgta ttttgattgt acgtcaaaac tataaaaaca tttactcttt gtcaaagagt
      301 agcagaaaag ctagaataaa atttttaatt ttattctagc taatagtgca agtaatagct
      361 tttgtagctt gcctcttgtc tgaataacgg acaagaggca ggagtttgta tttgttctaa
      421 atgagtattt catttagaac aaatacatcg atgatgaaca ttgcttacaa gaatagagat
      481 ttgagtgatg aagaatttaa agaagaagct catcagttta gagataaaga gataaaaata
      541 ctcgaagaaa aattaaagga acttaatatt tcttgtaagg ttgttggaat aaatagtata
      601 aaagatatga acgagtataa agagattatg gaaaatgtta atcaagcaaa agaggaatta
      661 aagagaatag atgaattaat agccgtcagg agctccagaa ttgatttttt agaggataaa
      721 acccttagaa ttacaggaaa ccaaagatga gcttaaaaac gaaatggaga gcctaaaaag
      781 agatttatct ttttttagaa acgaaaatac tcgactgaaa aatgtagttt cagattgtat
      841 caaggtagta tttttggggt atttttagta gaaagtatat tgtaatttct gagcgattta
      901 tgccgtgaaa gctacttgac cgtaagctag atcaaagtac gctagtcagg gacgagccga
      961 aaggctgtag cgtttcggag cggcacggac aaagtacgtc gacctaggtt acttgcggtc
     1021 aagtagacca tggaataaaa caagcgggta tgatataaaa aagttatcgg caaaccgaaa
     1081 tatagacttg tttttttgtt tataaaaatg tattattata ttgagaataa gattgtttaa
     1141 tttatttaga gaggagtgta agttgatcag taaacgattt taattctgcc tttaaataac
     1201 aaggagtttg ttatgaataa aaaatttttg aaatgtggta ctttattttt gatttcttgt
     1261 tctattttag gaagtactat tcctgcagtt acagtatttt ctgatgaagt aacaattact
     1321 tataattcag agaataattc agaaaaaaat gaattatata atcaactttc tgctgaaaaa
     1381 aaaggacagt ttgatgagtt ggtaagtaat ttgaatttga gcgaacaaga acaattagac
     1441 ttgttgcagc agtataaaga ggaacatcct cggcgagcta aaagggggat aaaatcagct
     1501 ataataaaaa aagtcgctcg tttccttgct gctaaagtag gacaaaaaag tgtagtggag
     1561 ataactgact atttatttga atggcaagac aatttagaag ctggagcgga gaattatctt
     1621 gtacaatatg gttgggatag aaatattgct cactggacaa taaagacagt tagctttatt
     1681 ttcttataag tcattatgaa taaagcttgg ttattttgga gtgtcatagt cttatatttt
     1741 tttataaagt tttttgataa agttttagat ataaagcttt ttggttctat tcaaatatgg
     1801 ctagataatc tccctattcc gatgaaaata ctgttaacaa tagcattagt tttgttttta
     1861 ttcattgtat ttccatatag aggaaaacgg taaaaacggt aattagatat ataaaaggag
     1921 ctgaaagctc cgtaaaaaac ctactcgaag agtaggtttt ttcttatctt gatactagta
     1981 ggaaataact ctcatgctat ttttagggtt tcgacagggt ctaaaccctt gatactactg
     2041 actttttagg taaaaaaatg cccttgactt ttttcaacgg atcttttata atttagttgt
     2101 tcagaaaaaa ttataaaaag agaaaaaagg caaaggtatt tttgtatttc tttgtaatta
     2161 caggtaaatt ataacatgga gaagtgggaa aatcaagata aaattctttt agataaaaat
     2221 aaaagaggca aggatagaaa ctggcgagga cgaaaattat taagtttgaa attggcagat
     2281 atttttaaag agttaggtta tagggaaacc ttgatagaac gcgttgagac ttgtggagat
     2341 actcttcgat ttattcgtcg agaagatggg agtttgcgtt tatatcaagc ctatttttgt
     2401 aagaataaat tgtgtcctat gtgtaattgg agacggtcaa tgaaatattc ttatcaaaca
     2461 tctcagatag ttgatgaagc aattaaagaa caaccaaaag ggcgttttct tttcttgact
     2521 ttgactgtga aaaatgttcc aggtaaagaa ttgaacgcga caattagcca actaactcag
     2581 tcctttgacc gtctttttag acgggcaaag gtaaagaaaa atctaatcgg gtttttacgt
     2641 tcggttgagg tgactcataa tcaagaagaa gagacctatc accctcatat ccatgttttg
     2701 atgatggtta agtctagcta ttttagtggg gctggagata attatgtatc tcaagaagaa
     2761 tgggggcgga tgtgggaaca gtcgcttaag gttgactatg tgccaatagt tgatattcgg
     2821 tcagttaaag aaataggaaa aggtcttaaa ggggcaattc ttgaaacggc aaaatatcca
     2881 attaagccga ttaagttaga tgttgaaaac aagcaagttg ttggtgattt gtataatggg
     2941 ttatatcgta aacggcaatt gggttacggt ggattgttta aagaaattcg gaagagattg
     3001 caactgtcta atgtcgaaaa tggagatctg gtttatattt ctgatgacaa tgatgaaatg
     3061 tcaaaaggta caaaaatagt cgcgatttgg aatgcgacta aacaaaacta ttttgtaaaa
     3121 aataagggtt ggaattaaag tatcaactct tttattataa cat
//
LOCUS       DAVEHY010000076         2814 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVEHY010000076 DAVEHY010000000
VERSION     DAVEHY010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.076"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            1..833
                     /locus_tag="VUZ44_002140"
                     /pseudo
     CDS             1..833
                     /locus_tag="VUZ44_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(919..1206)
                     /gene="tnpB"
                     /locus_tag="VUZ44_002141"
                     /pseudo
     CDS             complement(919..1206)
                     /gene="tnpB"
                     /locus_tag="VUZ44_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1467..1766)
                     /locus_tag="VUZ44_002142"
     CDS             complement(1467..1766)
                     /locus_tag="VUZ44_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU0320980.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1931..2382)
                     /locus_tag="VUZ44_002143"
                     /pseudo
     CDS             complement(1931..2382)
                     /locus_tag="VUZ44_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            2464..2814
                     /locus_tag="VUZ44_002144"
                     /pseudo
     CDS             2464..2814
                     /locus_tag="VUZ44_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          871 a          505 c          554 g          884 t
ORIGIN      
        1 acgtggtggt cgtaaccatg catatatgac agttgaggaa gagaaagcct ttcttgcccg
       61 ccatttgaag gctgcagagg caggagaatt tgttacaatt gatgccttat ttcaggctta
      121 taaaaaggag ttaggtcgtt cctacacacg tgatgccttc tatcaactgt tgaagcacca
      181 tggttggcga aatattatgc cacgtccaga acatcctaag aaagcagacg ctcaaaccat
      241 tgttgcgtct aaaaataaaa tctcaattca agaagataag aaagcgcttt aaatatagta
      301 gacgttttcg taaggttcgc ttgatgtacc aagatgaggc tggtttcggt agaatcagta
      361 aactgggatc ttgttgggct ccaataggag taggtccaca tatccatagt cactatatac
      421 gagaatttcg ctattgttat ggagctgttg atgcccatac aggcgaatca tttttcttaa
      481 tagctggtgg atgtaatact gagtggatga acgccttttt agaagagctt tcacaagctt
      541 atccagatga ttatctttta ctcgttatgg acaatgctat atggcaaaaa tcaagtatct
      601 taaagattcc gactaatatt ggctttgcat ttattcctcc atacacacca gagatgaacc
      661 ccattgaaca agtgtggaaa gagattcgta aatgtggatt taagaataaa gcctttcgaa
      721 ctttggaaga tgtcatgaat caacttcaag atgtcataca aggactggag aaggaggtga
      781 taaagtccat cggtaatcgg agatggaata gaatgctttt tgaaagcaga tgagtataaa
      841 aagaaagtcc tcatttcaat agaaatcacg actttctgat agatttattt ttggagtgat
      901 agaaaagccc ttcatcagtc aatctacttg ttcaggtgcg agagctttga catccttttc
      961 tgcacttagc caagtcagtt ttccgttctc aaagcgttta tatagtagcc aaaatccttg
     1021 accatcccag taaagggctt taaagcggtc tttacgtcca ccacaaaaga gaaagacttg
     1081 accggagaaa gaatccaatt caaagtgggt tttaactaca taggctaatg agtctattcc
     1141 ctacctcata tctgtcttac cacaaacaag gtgaacttga cctaaatcac ttagttgaat
     1201 tatcatagta caataccttt cctccgataa ttatttttta tctagtatac tggaagttgg
     1261 ggaattagga tagatacctt gttatgacgc gcttacgtaa cttgtaacta gctgcctagt
     1321 ttgatctttg cttcttcatt gattagcagt agatttcaaa atgataaaaa cgcataatag
     1381 tgggtgtaga aactcttgtt actatgcgtt ttgttatgga aagacttatt ggactttctc
     1441 tcaaatcgag tttttactca attttcttac ttgattggga ttgaaattcc aattaatttc
     1501 tctgagtaga gtgtcttgat attggcttca tcaacagagg tcttatcaat tttacgtttc
     1561 aagaaaaatt cttgaatggt ttcgatttca ggctcacgaa tagcacggtg tttgtttgag
     1621 atgaggattt catagtgaag cggagcttgg gtaaaaataa catctgtatt ccctgcagaa
     1681 taaacctcaa caagggttgc atcggtactt tctagttgac tttttacaag ttgcgagtgt
     1741 gagtttgtcg tattgataag cttcataata tttcctccga ttttctaatt ctattataac
     1801 actttttgaa tagagtcgct tgatttatac tcaatgaaaa tcaaagagca aactaggaag
     1861 ctagccgcag gctatacttg agtacggtaa ggcgacgctt acgtgatttg aattttattt
     1921 tcgaagagta ttagccaatc ttatgctgtt ttttccaaga ttcaatggcc catttatggc
     1981 taccacgttt aaggtttttg atagcctcgt caatagggaa ccaggcaata tgattaaagt
     2041 tttctagtgg cttttgtact tctttgaaag gagttgcttc atagaggtag gcaggattgt
     2101 agtagtaggt atcacgatga cgagaataga aatattcgtc agcttgtccg taataggtac
     2161 caatttctgc tgtgaaacca agctcttcaa tcaactcacg ctttagggct tcctgatgat
     2221 tttcacctgc ttcaattttt ccacatggta ggaaccaagc accatttggt tcttgaacaa
     2281 gaacaatttg tttttgttca ggattaggga taactgcata tacgccatag cgagcaatat
     2341 agtctgtatt cacttttttt ctccgaaagt tgggtttgcc attgcatttt cctcattatc
     2401 tagtatcgtt attattatag taaaatgaac caaaaatagt acacaatgtg gtataatctt
     2461 cttatggcat attcaataga ttttcgtaaa aaagttctct cttattgtga gcgaataggt
     2521 agtataacag aagcatcaca cgttttccaa atctcacgta ataccattta tggctggtta
     2581 aagctaaaag agaaaacagg agagctaaac caccaagtaa aaggaacaaa accaagaaaa
     2641 gttgatagag atagacttaa aaactatctt actgacaatc cagatgctta tttgactgaa
     2701 atagcttctg actttggctg tcatccaact accatccact atgcgctcaa agctatgggc
     2761 tacactcgaa aaaaagaacc acacctacta tgaacaagac ccagaaaaag tagc
//
LOCUS       DAVEHY010000077         2174 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVEHY010000077 DAVEHY010000000
VERSION     DAVEHY010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2174
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.077"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            123..662
                     /locus_tag="VUZ44_002145"
     CDS             123..662
                     /locus_tag="VUZ44_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU0320981.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            729..1139
                     /locus_tag="VUZ44_002146"
     CDS             729..1139
                     /locus_tag="VUZ44_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU0320982.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1255..>2174
                     /gene="pavB"
                     /locus_tag="VUZ44_002147"
     CDS             1255..>2174
                     /gene="pavB"
                     /locus_tag="VUZ44_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU0320983.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFLVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININVLVAKETVEKAVK"
BASE COUNT          668 a          412 c          485 g          609 t
ORIGIN      
        1 ttttgaggtt gcagatagaa ctgacgaagt cagtaacatc tatacggcaa ggcgacgttg
       61 acgcggtttg aagagatttt cgaagagtat aagaaaaaat cagtccccta aaggagtaga
      121 ttatgaagtt attgtctatc gcaatttcta gctataatgc agcagcctat cttcattact
      181 gtgtggagtc gctagtgatt ggtggtgagc aagttgggat tttgattatc aatgacgggt
      241 ctcaggatca gactcaggaa atcgctgagt gtttagctag caagtatcct aatatcgtta
      301 gagccatcta tcaggaaaat aaatgccatg gcggtgcggt caatcgtggc ttggcagagg
      361 cttctgggcg ctattttaaa gtagttgaca gtgatgactg ggtggatcct cgtgcctact
      421 tgaaaattct tgaaaccttg caggaacttg agagcaaagg tcaagaggtg gatgtctttg
      481 tgaccaattt tgtctatgaa aaggaagggc agtctcgtaa gaagagtatg agttacgatt
      541 cagtcttgcc tgttcggcag atttttggct gggaccaggt cggaaatttc tccaaaggcc
      601 agtataccat gatgcactcg ctgatttatc ggacagattt gttgcgtgct agccagttct
      661 aactgcctga acatactttt tatgtcgata atctctttgt ctttacgccc cttcagcagg
      721 tcaagaccat gtactatctg cctgtcgatt tctatcgtta tttgattggg cgtgaggacc
      781 agtctgtcaa tgagcaagtg atgattaagt gcattgacca gcaactcaag gtcaatcgac
      841 tcttggtaga ccaacttgat ttgtcccaag tgagtcatcc caaaatgcga gaatatctgc
      901 tgaatcatat tgaaatcacg acggtgattt ccagtaccct gctcaaccga tctggaacag
      961 cggagcatct ggcaaaaaaa cgccaattgt ggacctatat tcagcagaaa aatccagaag
     1021 tctttcaggc tattcgtaag accatgttga gccgtttgac caaacattct gtcttgccag
     1081 atcgcaaact gtccaatgtc gtctatcaaa tcaccaaatc tgtttatgga tttaattaat
     1141 ataagtgttt tataagaggg atttaagaaa aattttaact ttttcttagt cctttttaat
     1201 ttcaggagat tatactagag tcatcaaata aagaaagact ctaaggagaa tcctatgaaa
     1261 ttcaatccaa atcaaagata tactcgttgg tctattcgcc gtctcagtgt cggtgttgcc
     1321 tcagttgttg tggctagtgg cttcttagtc ctagttggtc agccaagttc tgtacgtgcc
     1381 gatgtggtca atccgacccc aggtcaagtc ttacctgaag agacatcggg aacgaaagag
     1441 ggtgacttat cagaaaaacc aggagacacc gttctcactc aagcgaaacc tgagggcgtt
     1501 actggaaata cgaattcact tccgacacct acagaaagaa ctgaagtgag cgaggaaaca
     1561 aactcttcta gtctggatac actttttgaa aaagatgaag aagctcaaaa aaatccagag
     1621 ctaacagatg tcttaaaaga aactgtagat acagctgatg tggatgggac acaagcaagt
     1681 ccagcagaaa ctactcctga acaagtaaaa ggtggagtga aagaaaatac aaaagacagc
     1741 atcgatgttc ctgctgctta tcttgaaaaa gctgaaggga aaggtccttt cactgccggt
     1801 gtaaaccaag taattcctta tgaactattc gctggtgatg gtatgttaac tcgtctatta
     1861 ctaaaagctt cggataatgc tccttggtct gacaatggga ctgctaaaaa tcctgcttta
     1921 cctcctcttg aaggattaac aaaagggaaa tacttctatg aagtagactt aaatggcaat
     1981 actgttggta aacaaggtca agctttaatt gatcaacttc gcgctaatgg tactcaaact
     2041 tataaagcta ctgttaaagt ttacggaaat aaagacggta aagctgactt gactaatcta
     2101 gttgctacta aaaatgtaga catcaacatc aatgtattag ttgctaaaga aactgtcgaa
     2161 aaagctgtta aaga
//
LOCUS       DAVEHY010000078         1966 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVEHY010000078 DAVEHY010000000
VERSION     DAVEHY010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1966
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.078"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(69..245)
                     /locus_tag="VUZ44_002148"
                     /pseudo
     CDS             complement(69..245)
                     /locus_tag="VUZ44_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            580..>1966
                     /gene="pcpA"
                     /locus_tag="VUZ44_002149"
     CDS             580..>1966
                     /gene="pcpA"
                     /locus_tag="VUZ44_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU0320984.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDEKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT          718 a          276 c          310 g          662 t
ORIGIN      
        1 gtacgctgaa caccaacaag actcttaaat cgtgcatcag ttagttgttt acttgcttca
       61 taattttgtt tcgcagggag tctattgact ctttggtagg tgtcaatgtt tttttcatct
      121 atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt ttcccagaaa
      181 gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc aaattttaag
      241 tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa gttgagtgat
      301 aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt aacccacttt
      361 aatttctttt ttaacacgtg ttaaaaaaga aattaaagtg ggttaatttt ccttgactta
      421 aaatttaaaa atgatatact gtgtttatgg agagatgaca atttataaaa tgtactactc
      481 tattctacta gataatgatt gaataaaact ttttataaca acggctagca aagttataat
      541 tttatatcta ttagaaaata aatatgtaag gaaatttaaa tgaaaaaaac tacaatatta
      601 tcattaacta cagctgcggt tattttagca gcatatgtcc ctaatgaacc aatcctagca
      661 gatactccta gttcggaagt aatcaaagag actaaagttg gaagtattat tcaacaaaat
      721 aatatcaaat ataaggttct aactgtagaa ggtaacatag gaactgttca agtgggtaat
      781 ggagttactc ctgtagagtt tgaagctggt caagatgaaa aaccattcac gattcctaca
      841 aaaatcacag taggtgataa agtatttacc gttactgaag tagctagtca agcttttagt
      901 tattatccag atgaaacagg tagaattgtc tactatccta gctctattac tatcccatca
      961 agcataaaaa aaatacaaaa aaaaggcttc catggaagta aagctaaaac tattattttt
     1021 gacaaaggca gtcagctgga gaaaattgaa gatagagctt ttgatttttc tgaattagaa
     1081 gagattgaat tgcctgcatc tctagaatat attggaacaa gtgcattttc ttttagtcaa
     1141 aaattgaaaa agctaacctt ttcctcaagt tcaaaattag aattaatatc acatgaggct
     1201 tttgctaatt tatcaaattt agagaaacta acattaccaa aatcggttaa aacattagga
     1261 agtaatctat ttagactcac tactagctta aaacatgttg atgttgaaga aggaaatgaa
     1321 tcgtttgcct cagttgatgg tgttttgttt tcaaaagata aaactcaatt aatttattat
     1381 ccaagtcaaa aaaatgacga aagttataaa acgcctaagg agacaaaaga acttgcatca
     1441 tattcgttta ataaaaattc ttacttgaaa aaactcgaat tgaatgaagg tttagaaaaa
     1501 atcggtactt ttgcatttgc ggatgcgatt aaacttgaag aaattagctt accaaatagt
     1561 ttagaaacta ttgaacgttt agccttttac ggtaatttag aattaaaaga acttatatta
     1621 ccagataatg ttaaaaattt tggtaaacac gttatgaacg gtttaccaaa attaaaaagt
     1681 ttaacaattg gtaataatat caactcattg ccgtccttct tcctaagtgg cgtcttagat
     1741 tcattaaagg aaattcatat taagaataaa agtacagagt tttctgtgaa aaaagataca
     1801 tttgcaattc ctgaaactgt taagttctat gtaacatcag aacatataaa agatgttctt
     1861 aaatcaaatt tatctactag taatgatatc attgttgaaa aagtagataa tataaaacaa
     1921 gaaactgatg tagctaaacc taaaaagaat tctaatcagg gagtag
//
LOCUS       DAVEHY010000079         1920 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVEHY010000079 DAVEHY010000000
VERSION     DAVEHY010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.079"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            6..434
                     /locus_tag="VUZ44_002150"
     CDS             6..434
                     /locus_tag="VUZ44_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320985.1"
                     /translation="MPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPI
                     TRKEISNWHIKASQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTFLS
                     GKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            529..958
                     /locus_tag="VUZ44_002151"
                     /pseudo
     CDS             529..958
                     /locus_tag="VUZ44_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1029..1187
                     /locus_tag="VUZ44_002152"
     CDS             1029..1187
                     /locus_tag="VUZ44_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU0320986.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            1280..1920
                     /locus_tag="VUZ44_002153"
                     /pseudo
     CDS             1280..1920
                     /locus_tag="VUZ44_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          607 a          362 c          416 g          535 t
ORIGIN      
        1 ctcctattcc taaagcccct ttagcgcata actttggctc agcttctatt atcgctcaca
       61 ccatccatca gaagtttaat ctgaaggtac ccaattatcg ccaagaagaa gattgggcta
      121 ggatgggttt accaatcaca cgtaaggaaa tctctaattg gcatatcaag gcgagtcaat
      181 actatttgga gcccctttat aacctcttgc gagagagact attgactcag cccttacttc
      241 atgcggatga aacttcttat agggtgctag agagtgatag tcagctgact tactattgga
      301 cttttttgtc aggtaaagca gagaaacaag ggattacgct ttaccaccat gatcagtgtc
      361 gaagtggttc agtagtacaa gaattcctag gagattattc tggctatgtg cattgtgata
      421 ttttgcggca gtaacttagg actttagtcc tctagttctg cctatgcgat agcagtccaa
      481 ggtttaggag caaggcgacg ctaagcttgg taaacttcga accgctcgtc tgcttatcgt
      541 caactggaag aagctgaact tgttggatgt tgggcgcatg tgagaaggaa gttttttgaa
      601 gcgccccccc aagcaagcgg ataaatcatc cttaggagct aaaggtttag cttattgtga
      661 tcagttattt tccttggaaa gagactggga ggctttgcca gctgatgaac gactacagaa
      721 acgtcaagaa catctccagc ccttaatgga agacttcttt gcttagtgcc ggcgtcagtc
      781 agttttagca ggttcaaaac taggaagggc aattgaatac agcctcaagt atgaagaaac
      841 ctttaagacc attttgaaag acggacatct ggtcctttcc aataatctag ctgaacgcgc
      901 cattaaatca ttggttatgg gacggagtaa aagagtccag tggactcttt tagcctaagc
      961 tcagtttaaa aaagcgaggg tggttatttt ctcaaagttt tgaaggagct aaagcaagag
     1021 ctattattat gagtttgttg gaaacagcta aacgtcatca attaaatagc gagaaatatc
     1081 tatcctatct tctagaatgt cttccaaacg aggaaactct cgtaaacaaa gaggttttag
     1141 aggcttattt accatggact aaagttgtac aagaaaagtg caaataagaa atctccagat
     1201 taggaactat ccgtgagttc tccagtctgg agatttttca atagacttcc tgcgaaacaa
     1261 aatatggtat aatagttcta tgaatgatga agcaagtaaa caactaaccg atgcacgatt
     1321 taagcgtctt gttggtgttc aacgcacgac ttttgaagag atgttagctg tattaaaaac
     1381 agcttatcaa cttaaacacg caaaaggtgg acgaaaacct aaattaagtc tagaagacct
     1441 tcttatggcc actcttcaat atgtgcgaga atatcgaact tatgaacaaa ttgcggctgt
     1501 ttttggtatt cacgaaagca acttaatccg tcggagccaa tgggttgaag taactcttgt
     1561 tcaaagtggt gttacgattt caagaactcc tctcagttct gaggacacgg taatgattga
     1621 tgcgacggaa gtaaaaatca atcgccctaa aaaaagaatt agcgaattat tctggtaaaa
     1681 agaaatttca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt
     1741 tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt cgcagaaata
     1801 tcagacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc
     1861 ctcaagcaca aacttcacgt aaatccagca aactcaaacc gctaacaatt gaagataaag
//
LOCUS       DAVEHY010000080         1866 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVEHY010000080 DAVEHY010000000
VERSION     DAVEHY010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.080"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VUZ44_002154"
     CDS             complement(3..968)
                     /locus_tag="VUZ44_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU0320987.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VUZ44_002155"
     CDS             complement(1086..1499)
                     /locus_tag="VUZ44_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU0320988.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VUZ44_002156"
     CDS             complement(1496..1732)
                     /locus_tag="VUZ44_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU0320989.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          544 a          364 c          276 g          682 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttat gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
     1861 caattg
//
LOCUS       DAVEHY010000081         1521 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVEHY010000081 DAVEHY010000000
VERSION     DAVEHY010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1521
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.081"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            1..471
                     /locus_tag="VUZ44_002157"
                     /pseudo
     CDS             1..471
                     /locus_tag="VUZ44_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            532..1495
                     /locus_tag="VUZ44_002158"
                     /pseudo
     CDS             532..1495
                     /locus_tag="VUZ44_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
BASE COUNT          469 a          247 c          317 g          488 t
ORIGIN      
        1 cttaagaatt ttaatagttt aaagcaccta gcacctgttt agattgatga aacaggattc
       61 gatacttatt tttatcgaga atatggtcgc tctttaaaag gtcagttaag aagaagatat
      121 tagaggattt ctttggttgc aggtctaacc aatggtgagt taatcgctcc aatgacttac
      181 gaagagacga tgacgagcga cttttttgaa gcttggtttc agaagttttt cttaccaaca
      241 ttaaacacac catcggttat tattatggat aatgtaagat tccatagaat ggggaagcta
      301 gaatttttat gcgaggagtt tgggcataaa cttttacctc ttcctcccta ctcgcctgag
      361 tacaatccta ttgagaaaac atgggctcat atcaaaaagc acctcaaaaa ggtattacca
      421 agttgcaata ccttttacga ggctcttttg tcttgttctt gtttcaattg actatatatc
      481 acggatacag ttgggaaaga agctattaat tatttggaga gtccttttgg gatgaacatg
      541 tcaaatatta ctatcagatg ggcaagaaat ggatctgagt caaacgatgc cttcttatgc
      601 tcaagtagtg agtctttatg atgatacaag tatctctgtt agtaataatg agacggacaa
      661 agtgttggct ggatccctct atactgatac aaatgaacag ggattaacga ttccaagcag
      721 tttactaaaa aattggaatg aacagacagg aaaaaatttg acagctaatg atcttattgg
      781 caaatcagtc tcagccagca ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt
      841 tcaaacgaag attgtacgtg taatcaatga tgaagatgac atggaggaca gcaacagttt
      901 catgctgtct catcaaatgg aaacgatttt gaaagaggct ggatttacga aagctgtatc
      961 ttattttatc ttggaactca aagatccatc acagacaaaa gtagtaacag aagaattaca
     1021 gaaaaataag aagtatactg tgctttctca acagagagtt cttgatattg tgattacctt
     1081 tattcgtgtt attcagggat tattgattgt gctttcatca caagctattg tggtagcagc
     1141 ggttatgatt ggtatcatta tttacatcaa tatcatgcaa cgttccaagg aaataggtgt
     1201 catgaaagca gttggttatc agaatcgtga tgtcaaagga atttttattt acgaggctat
     1261 ctggattgta ggcatcgcct tgctgctggc atttttggtt gcacaagggg tgggaagttt
     1321 ggcgaatgcg attgtaagtc acttttaccc atccatcact aaggtttttg aattaaatct
     1381 tttatctgtt ttaggaactc tagttttcgc tctattactt ggttatgtct cagcctactt
     1441 cccggcgcgt aagattagta aaatggatcc tgtagaaccg ttacgctatg aatagtaagg
     1501 gattccttga tttacagtct t
//
LOCUS       DAVEHY010000082         1492 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVEHY010000082 DAVEHY010000000
VERSION     DAVEHY010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.082"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..909)
                     /gene="pspC"
                     /locus_tag="VUZ44_002159"
     CDS             complement(<1..909)
                     /gene="pspC"
                     /locus_tag="VUZ44_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HEU0320990.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEKEGST
                     QAATSFNRGNGSQAEQRGELDLERDKAMKAVSEYVGKMVRDAYVKSDRKRHKNTVALV
                     NQLGNIKNRYLNEIVHSTSKSQLQELMMKSQSEVDEAVSKFEKDSFSSSSSGSSTKPE
                     TPQPENPEHQKPTTPSPDTKPSPQPEGKKPSVPDINQEKEKAKLAVVTYMSKILDDIQ
                     KHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFK
                     KGLTQDTPKEPGNKKPSAPKPGMQPSP"
     gene            1112..>1492
                     /locus_tag="VUZ44_002160"
     CDS             1112..>1492
                     /locus_tag="VUZ44_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320991.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKNSMTDIAHQL"
BASE COUNT          419 a          297 c          250 g          526 t
ORIGIN      
        1 aggacttggt tgcatacctg gttttggagc agatggtttt ttgttacctg gttcttttgg
       61 tgtgtcctga gttaagcctt ttttgaattt agtcacaact gcatccatgt ctgcaaatat
      121 cttgtggact gtattttcaa tttctacttt ggtatttaca ttatcaattt cagaaagagc
      181 ttgcttttta agctcatcaa gctccttaat aagagcaaca atctgacgat gtttttcttt
      241 ctgcagatga tgtttttgta tatcatctaa aatcttgctc atgtaggtta ctacagcaag
      301 cttagctttt tctttttcct gattaatgtc tggtacgctt ggtttcttgc cttctggttg
      361 agggcttggt ttggtatccg gagatggagt tgttggtttt tgatgctctg gattttccgg
      421 ctgcggagtt tctggtttag tggaggatcc tgaacttgac gaagaaaatg agtccttttc
      481 aaatttagac acagcttcat ctacttctga ttgactcttc atcatcagtt cctgtagttg
      541 gctttttgag gttgaatgaa ctatttcatt caaatacctg ttcttaatgt ttcccaactg
      601 gttaactaga gctacagtat ttttatgtcg ttttctatct gattttacat aggcatctct
      661 caccattttt cctacatatt cactgaccgc tttcattgcc ttatctcgtt ctaaatcgag
      721 ttctccacgt tgttctgcct gacttccatt tcccctatta aaagaagtgg ctgcttgggt
      781 acttccctct ttctctgtcg catgtacaac acttcccata aaaagactgg caacagctac
      841 gctagctact cctacactaa atttacgaat ggaataacgc attcttcgct catgatttga
      901 tttaaacatg tctatattct ccataatttt aattaactac agtatatcct gctaatatga
      961 attgtatatg aaatttgcta cattatttgg ctctataata tttgtagtgg gtaaatcccc
     1021 tatggatatt atggagccta ttttgtgtag aaaaaaagtc ccatatgacc tataatgaaa
     1081 agcgacaaaa caactcatta gaaagattca tatggaacaa ttacatttta tcacaaaatt
     1141 actagacatt aaagacccta atatccagat tttagacatc atcaataaag atacacacaa
     1201 ggaaatcatc gccaaactgg actacgacgc cccatcttgc cctgagtgcg gaagtcaaat
     1261 gaagaaatat gactttcaaa aaccttctaa aattccttat cttgaaacaa ctggtatgcc
     1321 tactagaatt ctccttagaa agcgtcgatt caagtgctat cactgttcaa aaatgatggt
     1381 cgctgaaact tctatcgtca agaaaaatca ccaaattcct cgtattatca accaaaaaat
     1441 tgcgcaaaag ttaattgaaa agaattctat gaccgatatt gcccatcagc tg
//
LOCUS       DAVEHY010000083         1406 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVEHY010000083 DAVEHY010000000
VERSION     DAVEHY010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.083"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(1..738)
                     /locus_tag="VUZ44_002161"
                     /pseudo
     CDS             complement(1..738)
                     /locus_tag="VUZ44_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(662..856)
                     /locus_tag="VUZ44_002162"
     CDS             complement(662..856)
                     /locus_tag="VUZ44_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0320992.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLREQVAYLTQKLYGKSSEKSVCPF
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1026..1376)
                     /gene="tnpB"
                     /locus_tag="VUZ44_002163"
                     /pseudo
     CDS             complement(1026..1376)
                     /gene="tnpB"
                     /locus_tag="VUZ44_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          409 a          282 c          250 g          465 t
ORIGIN      
        1 atctcctagg aattcttgta ctactgaacc acttcgacac tgatcatggt ggtaaagcgt
       61 aatcccttgt ttctctgatt tacctgacaa aaaagtccaa tagtaagtca gctgactatc
      121 actttctaag acccgataag aggtttcatc tgcatgaaga agagcttgtt ctaacaactt
      181 ttctcataaa aggttataaa gagactctaa atagtattga ctcgtcttga tatgccaatt
      241 agaaatttcc ttacgtgtga ttggtaaacc catcttagcc caatcttctt cttagcgata
      301 attgggtacc ttcagattaa acttctgatg gatggtgtga gcgataatag aggctgaacc
      361 aaggctatgc gccaaagggg ctttagggac aggagctttt acaattttat cacttggatt
      421 tttatcactg catgcttggc atttgtaagc gtgttggata tgatccactc tttttaattg
      481 cgcaggaata aagaccaatt cttgtcgttg aaggctcgct ccaatctctt ttaaatcgtc
      541 ctgacaatca gggcaaatgc tctcttctac ttgatgatga acttcttctg aatcaaattg
      601 ggcaagaata gcttgacgtt tccctttagc tttcttacgt ttataggtga tttcttctct
      661 ttcaactggg taagtcagag tcttcttcca tattttgttc ctcttcaaaa agactgagtt
      721 gtccaaaagg gcaaacactt ttctcagagg attttccata gagcttttgc gttagataag
      781 ccacttgttc acgcagaagg gaaagttcat tagtgagact atcaattata gcactctgtt
      841 gttgaatgat tttcaatctt ctcccataga ctttcctcct tatttcctaa ctttattata
      901 tagtgtattg aatctataac agtacacctt gactgctaaa atatttctat aaattaattt
      961 gacttttctg atagagatgt tcatatctta tttcaattca ctatactaaa aagaaagtcc
     1021 tcatttcaat agaaatcacg actttctgat aaatttattt tgggagtgat agaaaagccc
     1081 ttcataagcc agtctatttg ttcaggtgtg agagctttga catcctttta tgtactggac
     1141 caagtcagtc tgccgttctc aaagcgttta tatagtagcc aaaatccttg accatcccag
     1201 taaagggctt taaagcggtc tttacgtcca ccacaaaaga gaaaaacttg accggagaaa
     1261 ggatctaatt caaaatgggt tttaaccaga taagccagtg aatcaatgcc ttgcctcata
     1321 tccgttttcc cacatacgag atagacctgc cctaggctag atagatgaat tgtcatagag
     1381 caacacctta tccaaaagct gttcta
//
LOCUS       DAVEHY010000084         1356 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVEHY010000084 DAVEHY010000000
VERSION     DAVEHY010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1356
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.084"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..382)
                     /locus_tag="VUZ44_002164"
     CDS             complement(<1..382)
                     /locus_tag="VUZ44_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEU0320993.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KNPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDL"
     gene            complement(386..718)
                     /locus_tag="VUZ44_002165"
     CDS             complement(386..718)
                     /locus_tag="VUZ44_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU0320994.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            complement(722..1021)
                     /locus_tag="VUZ44_002166"
     CDS             complement(722..1021)
                     /locus_tag="VUZ44_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320995.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEIEKGE"
     gene            complement(1030..1293)
                     /locus_tag="VUZ44_002167"
     CDS             complement(1030..1293)
                     /locus_tag="VUZ44_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0320996.1"
                     /translation="MKENGEFIRCKNVSDDFYMYRDVQKRPVIVNGRRQFKDVETVWA
                     FNQWGGTIATINVAVLLNHEFYIMKFDAEGNPDWTVPTVEPKE"
BASE COUNT          323 a          326 c          261 g          446 t
ORIGIN      
        1 ccaagtcgtc tgtatcaaga gtcttcggca aacctgcttc atctgctaga ttgcgtaaga
       61 gttcgatata aaggcggtag tccgtcatga actcttcttt agttgaatgg ctttcaatca
      121 gttcaaccgc tgcgtaactc tcagtattcc aaccgccccc aacatcccaa cttccgttgt
      181 tcacaggacc tacttgcatg acacggccat ttccgacaac atgtgaaaag aaccctagtt
      241 cagggttctt tctatagtgg taatcagcct cattttgagc tgttgagtta cggttgcctg
      301 ttgagtgggc gtgtacttgt cgataaggct gcaccccaac ctggggcaag cctgttcgta
      361 gtctgtttct atcgatatcc attccctatc gtcctttcca tgcgtcattc atctgcttca
      421 ctgctgactc tacgaaggtg tctaagtctt tgtcagtcat gctaatattg tattttgtaa
      481 gctcagcacg gactttagcg cgagcctgtg ccagtttttc atctcccttg tagccagttt
      541 cagcagctac ctgctccacg gcattaactg cgttcttagc caagatttca acaatcttga
      601 tagtcttttc tccacctttt ttgacgaggt attccttgac tgccttgact gcgataccag
      661 ccaaaataac aaggatgctg attgctccat tagtaatgat ttcagtaatt tgttgcattt
      721 gttattctcc tttttcgatt tcttccatgc ggtcgttcat gcgaaccatt tctttttgaa
      781 tgtctccgac cgtgtgagtg attgtggtta attctgtagt ggtcttttct aggtgagtca
      841 tcaaacgctc ttctcgtcta ttagagtcgg cctttgattg ctcgtgcaaa tccataatct
      901 tcttctctcg cttgtccgaa gtcttgataa gatatcgaat gataataaaa aaaagcaaga
      961 taaacaaaat cgcccaagct acctgacttt gagcgatttt ttcagcttct tcaattggca
     1021 tacaacctcc tattctttag gttctaccgt tggaaccgtc cagtcaggat tgccctctgc
     1081 atcaaatttc atgatataga attcatgatt caacagaacg gctacgttga ttgttgcgat
     1141 tgtaccaccc cactgattga acgcccaaac ggtttcaaca tccttgaatt ggcgacggcc
     1201 atttacaatc acaggacgtt tttgaacgtc acgatacata tagaagtcat cgcttacatt
     1261 cttgcaacga atgaactctc cattttcttt catgtagcgc aaagcactcg caagatcaaa
     1321 tggttctgtg atttttgtaa ggtctagtaa gttatc
//
LOCUS       DAVEHY010000085         1198 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVEHY010000085 DAVEHY010000000
VERSION     DAVEHY010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1198
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.085"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            432..1142
                     /gene="deoD"
                     /locus_tag="VUZ44_002168"
     CDS             432..1142
                     /gene="deoD"
                     /locus_tag="VUZ44_002168"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU0320997.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
BASE COUNT          353 a          214 c          268 g          363 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa aggaattgac cccaccctaa
      181 aagtagtggg aaaaagatag ttgatctagc gagcatcgct cactgcgccc aactcctatt
      241 ttcccttcgc tttttgatgg gtttggtatc tttctcaata taaaatataa aataaagaaa
      301 ggtagagcgt gtgttttgat ttgaacacga gcggaaaact cggaaaatag ataatctgac
      361 tgaaaaatca ggatttctcg tcaggttcct aattttcagt cgttttcttc tcgctctttg
      421 tatcataaat tatgtctatc catattgctg ctcagcaggg tgaaattgct gataaaattc
      481 ttcttcctgg ggatcctctt cgtgctaagt ttattgcgga gaatttcctt gatgatgctg
      541 tttgttttaa cgaagtgcgt aacatgtttg gttacactgg tacttacaag ggtcactgtg
      601 tatctgtcat gggaactggg atgggaatgc catctatttc gatttatgcg cgtgagttaa
      661 tcgtagacta cggtgtgaag aaattgattc gtgtgggaac tgcaggttct ttgaatgaag
      721 aggttcatgt tcgtgaatta gttttggcgc aggcggctgc aaccaactca aacatcgttc
      781 gtaatgactg gccacagtac gattttccac aaattgctag ctttgatttg cttgataaag
      841 cctaccatat cgccaaaaaa cttggtatga ctactcacgt tgggaacgtt ttgtcatctg
      901 atgtctttta ctcaaattac tttgaaaaga atatcgagct tggtaaatgg ggagtcaagg
      961 ctgtggaaat ggaagcagca gctctttact atcttgctgc ccaataccat gttgatgcgc
     1021 tagctatcat gaccatctct gatagcttgg tcaatccaga cgaagacaca actgcagaag
     1081 aacgtcaaaa taccttcact gatatgatga aggttggttt ggaaaccttg attgcagaat
     1141 aattatagcc aaaaaggggc tctttgtcaa ctgtagtggg ttgaaaaaaa gctaagct
//
LOCUS       DAVEHY010000086         1194 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVEHY010000086 DAVEHY010000000
VERSION     DAVEHY010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.086"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..>1194
                     /gene="pspC"
                     /locus_tag="VUZ44_002169"
     CDS             <1..>1194
                     /gene="pspC"
                     /locus_tag="VUZ44_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEU0320998.1"
                     /translation="AKVESEKAEAIRLEEIKTDREEAKRKADAKLKEAVEKNAANSEQ
                     GEPKRRVKRGVLGEPATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEA
                     KKKAEDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELVNEEAKPRNEEKIKKAK
                     AKVESEKAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAE
                     EPNPAPAPKPEKPADQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKPEQPAPAPK
                     TGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWFQYNGSWYYLNANGD
                     MATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNSNGAMVTGWLQNNGSWYYLNAN
                     GSMAT"
BASE COUNT          474 a          237 c          281 g          202 t
ORIGIN      
        1 aagcgaaagt tgagagtgaa aaagctgagg ctataaggtt agaagaaatc aagacagatc
       61 gtgaagaagc taaacgaaaa gcagatgcta agttgaagga agctgttgaa aagaatgcag
      121 cgaattcaga gcaaggtgaa ccaaagaggc gggtaaaacg aggagttctt ggagagccag
      181 caacacctga taaaaaagaa aatgatgcga agtcttcaga ttctagcgta ggtgaagaaa
      241 ctcttccaag cccatccctg aaaccagaaa aaaaggttgc agaagctgag aagaaggttg
      301 aagaagctaa gaaaaaagcc gaggatcaaa aagaagaaga tcgccgtaac tacccaacca
      361 atacttacaa aacgcttgaa cttgaaattg ctgagtccga tgtgaaagtt aaagaagcgg
      421 agcttgaact agtaaacgag gaagctaaac ctcgaaacga ggaaaaaatt aagaaagcaa
      481 aagcgaaagt tgagagtgaa aaagctgagg ctacaaggtt agaaaaaatc aagacagatc
      541 gtaaaaaagc agaagaagaa gctaaacgaa aagcagcaga agaagataaa gttaaagaaa
      601 aaccagctga acaaccacaa ccagcgccgg ctcctcaacc agaaaaacca gctgaagagc
      661 ctaatccagc tccagctcca aaaccagaga agccagctga tcaaccaaaa gcagaaaaac
      721 cagctgatca acaagctgaa gaagactatg ctcgtagatc agaagaagaa tataatcgct
      781 tgactcaaca gcaaccgcca aaaccagagc aaccagctcc tgcaccaaaa acaggctgga
      841 aacaagaaaa cggtatgtgg tacttctaca atactgatgg ttcaatggcg acaggatggc
      901 tccaaaacaa tggctcatgg tactacctca acagcaatgg cgctatggcg acaggatggt
      961 tccaatacaa tggttcatgg tactacctca acgctaatgg tgatatggcg acaggatggt
     1021 tccaatacaa tggttcatgg tactacctca acgctaatgg tgatatggcg acaggatggc
     1081 tccaatacaa tggttcatgg tactacctaa acagcaatgg tgctatggta acaggatggc
     1141 tccaaaacaa tggctcatgg tactacctaa acgctaacgg ttcaatggca acag
//
LOCUS       DAVEHY010000087          958 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVEHY010000087 DAVEHY010000000
VERSION     DAVEHY010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.087"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..899
                     /gene="lytB"
                     /locus_tag="VUZ44_002170"
     CDS             <1..899
                     /gene="lytB"
                     /locus_tag="VUZ44_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEU0320999.1"
                     /translation="KNETVDGYQLESDGKWLGGKATNENAAYYQVVPVTANVYDSDGE
                     KLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGH
                     RFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDDFKLENPFLFKDLTEATNYSAE
                     ELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNN
                     FFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASD
                     PYWGEKIASVMMKINEKLGGKD"
BASE COUNT          316 a          147 c          215 g          280 t
ORIGIN      
        1 cgaaaaatga gacagtagat ggttatcagc ttgaaagcga tggtaaatgg cttggaggaa
       61 aagctacaaa tgaaaatgct gcttactatc aagtagtgcc tgttacagcc aatgtttatg
      121 attcagatgg tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg
      181 atagaaaaag tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga
      241 aaacagaaga tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg
      301 atggccaccg tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc
      361 tttctgatat ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatgatt
      421 ttaagcttga gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg
      481 aagaattgga taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg
      541 gcgctacttt taaggaagcc gaagaacatt accatatcaa tgccctttat ctccttgccc
      601 atagtgccct agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct
      661 ttggcattac agcctatgat acgacccctt acctttctgc caagacattt gatgatgtgg
      721 ataagggaat tttaggtgca accaagtgga ttaaggaaaa ttatatagat aggggaagaa
      781 ctttccttgg aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg
      841 gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa gctaggtggc aaagattagt
      901 actataagtg aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaa
//
LOCUS       DAVEHY010000088          914 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVEHY010000088 DAVEHY010000000
VERSION     DAVEHY010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.088"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..>914
                     /locus_tag="VUZ44_002171"
     CDS             <1..>914
                     /locus_tag="VUZ44_002171"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0321000.1"
                     /translation="AEAEALVDADSDAEVLAEAEALVDAEADALVLAEAEALVDAEAE
                     ALVDADSDALVLAEAEALVDADSEALVDAETEALVLAEADALVDAEADALVDAEAEAL
                     VLAEAEALVDADSEALVDAETEVLVEAKAEALVEAEAEALVDADADALVDAEADALVD
                     AEAEADVDADSDALVDAEAEALVDADADALVLAEADALVDADADALVDAEADALVDAD
                     ADALVDAEAEALVDAEAEALVLADSDALVDAEAEALVDAEAEALVDAEAEALVDAEAE
                     ALVDAEADALVDADADALVDAEADALVE"
BASE COUNT          177 a          198 c          313 g          226 t
ORIGIN      
        1 ttgctgaagc tgaggcgctt gtcgatgcag attcagacgc tgaggtgctt gctgaggctg
       61 aagcacttgt tgatgcggaa gctgatgcac tagtacttgc tgaagctgaa gcgcttgtcg
      121 atgctgaggc tgaggcactt gttgatgcgg attcagacgc acttgtgctt gctgaggccg
      181 aggcactggt tgatgcggat tcagaggcac tggttgacgc tgagactgaa gcacttgtgc
      241 ttgctgaagc tgacgcactt gtcgatgctg aggctgacgc actggttgac gctgaagctg
      301 aggcgctggt acttgctgag gctgaggcac ttgttgatgc ggattcagag gcactggttg
      361 acgctgagac tgaagtactc gttgaggcta aagctgaggc actcgttgag gctgaagccg
      421 aagcactcgt tgatgcggat gctgacgcac tcgttgatgc ggaagccgac gcacttgttg
      481 acgctgaggc tgaggcagac gttgatgctg attcagacgc acttgttgat gctgaagccg
      541 aggcgcttgt tgatgcggat gctgacgcac tggtgcttgc tgaagctgat gcactcgttg
      601 atgcggatgc tgacgcactg gttgacgctg aggctgacgc actcgttgat gcggatgctg
      661 acgcactggt tgacgctgag gctgaagcac tcgttgatgc ggaagccgag gcactggtgc
      721 ttgctgattc agatgcactt gtcgatgctg aagccgaggc acttgtcgac gctgaggctg
      781 aggcactggt tgatgctgaa gctgaagcac ttgttgatgc tgaagctgaa gcacttgttg
      841 atgctgaggc tgacgcactc gttgatgcgg atgctgacgc actggttgac gctgaggctg
      901 acgcacttgt tgag
//
LOCUS       DAVEHY010000089          857 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVEHY010000089 DAVEHY010000000
VERSION     DAVEHY010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.089"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(1..857)
                     /locus_tag="VUZ44_002172"
                     /pseudo
     CDS             complement(1..857)
                     /locus_tag="VUZ44_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          269 a          140 c          186 g          262 t
ORIGIN      
        1 gaatagtgta gttgaagggc gttgacgatt ttctctttgt cctttagaaa ggctttaaag
       61 acagtctgaa aaagaggatg aacctgcttt agattgtcct caatgagtcc gaaaaatttc
      121 tccggtttct tattctgaaa gtgaaacagc aagagttgat agagctgata gtggtgtttc
      181 aagtcttctg aatagcttaa aatcttgtct aaaatctctt tattggttaa gtgcatacga
      241 aaagtaggac gataaaatcg cttatcactc agtttacggc tatcctgttg tatgagcttc
      301 cagtagcgct tgatagcctt gtattcatgg gattttcgat gaaactgatt catgatttga
      361 acacgcacac gactcatagc acggctaaga tgttgtacaa tatgaaagcg ttcaagaacg
      421 attttagcat tcgggagtga aacagtctgg gagactgttt cagcctgagt ctagaaattt
      481 gaaagcgaag ctgtttagcc aagtcatagt aaggactaaa catatccata gtaatgattt
      541 tgacgcgaca tcggacaact ctatcatatt taagaaagtg atctcggatg acagcttgtg
      601 ttctaccctc aagaacagtg atgatattga gattgttaaa atcttgcgca atgaagctca
      661 tctttccctt tgtaaaagca tactcatccc aagatataat ctcaggaaga caagaaaaat
      721 catgtttaaa gtgaaaatca ttgagcttac gaataacagt tgaagttgag atggaaagct
      781 gatgggcaat atcggtcata gaaatctttt caatcaactt ttgagcagtc ttttggttga
      841 tgatacgagg gatttgg
//
LOCUS       DAVEHY010000090          844 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVEHY010000090 DAVEHY010000000
VERSION     DAVEHY010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.090"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..769)
                     /locus_tag="VUZ44_002173"
     CDS             complement(<1..769)
                     /locus_tag="VUZ44_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000878975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chordopoxvirus G3 family protein"
                     /protein_id="HEU0321001.1"
                     /translation="MVLADSDALVLADSDALVLAEAEALVDADSDAEVLAEAETLVDA
                     EADALVLADSDALVLAEADVLVDAEADVLVDAEAEALVLAEAEALVLAEADALVDAEV
                     EALVLAEAEALVDAETEALVDAEAEALVDADSDAEVLAEADALVDAEADALVDAEAEA
                     LVLAEAEALVLAETDALVDAEAEALVDADSEALVLAEAEALVDAEAEALVLAEAEALV
                     DADSDAEVLAEAETLVDAEADALVLAEAEALVDAEAEA"
BASE COUNT          217 a          269 c          191 g          167 t
ORIGIN      
        1 ctgcctcagc ctcagcatcg acaagcgctt cagcttcagc aagtactagt gcatcagctt
       61 ccgcatcaac aagtgtctca gcctcagcaa gcacctcagc atctgaatca gcgtcaacca
      121 gtgcttcagc ctcagcaagt accagtgctt cagcttccgc atcaacgagt gcttcggcct
      181 cagcaagtac aagtgcctct gaatccgcat caaccagtgc ctcggcttca gcgtcaacca
      241 gtgcatcagt ctcagcaagc acaagtgctt cagcttcagc aagcacaagt gcttcggctt
      301 cagcgtcgac aagtgcgtca gcttcagcat caacgagtgc gtcagcctca gcaagcacct
      361 cagcgtctga atcggcatca acaagtgctt cggcttcagc atcaacaagt gcttcagtct
      421 cagcatcaac gagtgcttca gcttcagcaa gcacaagcgc ctcgacttcc gcatcaacga
      481 gtgcgtcagc ctcagcaagc acaagtgctt cagcttcagc aagcacaagc gcctcggctt
      541 cagcatcaac gagtacgtca gcttccgcat caacgagtac gtcagcttca gcaagtacca
      601 gtgcatcaga gtcagcaagt accagtgcgt cggcttcagc gtcgacaagt gtctcagcct
      661 cagcaagcac ctcagcatct gaatcagcgt caaccagtgc ttcagcctca gcaagtacaa
      721 gtgcatcaga gtcagcaagt accagtgcat cagagtcagc aagtaccagt gcctcggctt
      781 cagcgtcaac cagtgcatca gagtcagcaa gtaccagtgc gtcggcttca gcgtcgacaa
      841 gtgc
//
LOCUS       DAVEHY010000091          735 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVEHY010000091 DAVEHY010000000
VERSION     DAVEHY010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.091"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(23..110)
                     /locus_tag="VUZ44_002174"
     tRNA            complement(23..110)
                     /locus_tag="VUZ44_002174"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(74..76),aa:Ser,seq:gct)
     gene            complement(117..190)
                     /locus_tag="VUZ44_002175"
     tRNA            complement(117..190)
                     /locus_tag="VUZ44_002175"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(154..156),aa:Ile,seq:gat)
     gene            complement(226..296)
                     /locus_tag="VUZ44_002176"
     tRNA            complement(226..296)
                     /locus_tag="VUZ44_002176"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Gly,seq:tcc)
     gene            complement(316..388)
                     /locus_tag="VUZ44_002177"
     tRNA            complement(316..388)
                     /locus_tag="VUZ44_002177"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(353..355),aa:Phe,seq:gaa)
     gene            complement(392..465)
                     /locus_tag="VUZ44_002178"
     tRNA            complement(392..465)
                     /locus_tag="VUZ44_002178"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(429..431),aa:Met,seq:cat)
     gene            complement(476..565)
                     /locus_tag="VUZ44_002179"
     tRNA            complement(476..565)
                     /locus_tag="VUZ44_002179"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(527..529),aa:Ser,seq:tga)
     gene            complement(576..649)
                     /locus_tag="VUZ44_002180"
     tRNA            complement(576..649)
                     /locus_tag="VUZ44_002180"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(613..615),aa:Ile,seq:cat)
     gene            complement(663..735)
                     /locus_tag="VUZ44_002181"
     tRNA            complement(663..735)
                     /locus_tag="VUZ44_002181"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(700..702),aa:Met,seq:cat)
BASE COUNT          206 a          206 c          167 g          156 t
ORIGIN      
        1 gagttacaaa ctctcattaa aacggagaat aagggattcg aacccttgcg ccagttaccc
       61 gacctaacga tttagcaaac cgtcctcttc agcctcttga gtaattctcc aattaatggg
      121 cacgagtgga ctcgaaccac cgacctcacg cttatcaggc gtgcgctcta accacctgag
      181 ctacgcgccc aagttaaaaa acttggtaat ttgaacaaag ttcaaagcgg gtgacgagaa
      241 tcgaactcgc gacaacagct tggaaggctg tagttttacc actaaactac acccgcataa
      301 atactatcaa taaaatggcg cgagacggaa tcgaaccgcc gacacatgga gcttcaatcc
      361 attgctctac caactgagct accgagcctt attgcgggag caggatttga acctacgacc
      421 ttcgggttat gagcccgacg agctaccgag ctgctccatc ccgcgttaat ataaaaggag
      481 gatgtgggat tcgaacccac gcacgctttt acacgcctga cggttttcaa gaccgttccc
      541 ttcagccgga cttgggtaat cctccaatat tcaaatggac cttgtaggac ttgaacctac
      601 gaccactcgg ttatgagccg agagctctaa ccagctgagc taaaggtccg acaagatcat
      661 tatagcggcg aaggggatcg aacccccgac ctcccgggta tgaaccggac gctctagcca
      721 gctgagctac accgc
//
LOCUS       DAVEHY010000092          729 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVEHY010000092 DAVEHY010000000
VERSION     DAVEHY010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.092"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..>729)
                     /locus_tag="VUZ44_002182"
     CDS             complement(<1..>729)
                     /locus_tag="VUZ44_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEU0321002.1"
                     /translation="MSWDEYAFTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRY
                     DRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQF
                     ERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHY
                     QIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPLFQTVFKTFLKNKEKIVNALQLPYSNA
                     KLEATNNLIKLIKRNAFGFRNFENF"
BASE COUNT          225 a          117 c          157 g          230 t
ORIGIN      
        1 gaagttttca aagtttcgaa aaccaaaggc attgcgtttg ataagtttga tgagattatt
       61 ggtcgcttcc aatttggcgt ttgaataggg tagttgaagg gcgttgacga ttttctcttt
      121 gttctttaga aaggttttaa agacagtctg aaaaagagga tgaacctgct tcagattgtc
      181 ctcaatgagt ccgaaaaatt tctcagggtc tttgttctga aagtgaaaaa gtaagagttg
      241 atagatctga tagtggtgtt tcaagtcttc tgaatagctt aaaatcttgt caagaatttc
      301 tttatttgtt aagtgcatgc gaaaagtagg gcgataaaaa cgtttatcgc tgagtttacg
      361 actatcctgt tggatgagtt tccagtaacg cttgatagcc ttgtattcat gagattttcg
      421 ttcaaactga ttcataattt gaacacgaaa acgactcatg gcacggctga gatgttggat
      481 aatatggaaa cgatctagaa cgattttagc acacggaaaa agctgtttag ccaagtcata
      541 gtaaggacta aacatatcca tcgtaatgat tttcacttga caacgaacgg ctctatcgta
      601 gcgaagaaag tgatttcgga tgacagcttg tgttctgcct tcaagaacag tgataatatt
      661 aagattatca aaatcttgcg caatgaaact catctttccc ttagtgaagg catactcatc
      721 ccaagacat
//
LOCUS       DAVEHY010000093          692 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVEHY010000093 DAVEHY010000000
VERSION     DAVEHY010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.093"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VUZ44_002183"
     tRNA            complement(74..147)
                     /locus_tag="VUZ44_002183"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VUZ44_002184"
     tRNA            complement(157..242)
                     /locus_tag="VUZ44_002184"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VUZ44_002185"
     tRNA            complement(250..321)
                     /locus_tag="VUZ44_002185"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VUZ44_002186"
     tRNA            complement(344..416)
                     /locus_tag="VUZ44_002186"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VUZ44_002187"
     tRNA            complement(435..516)
                     /locus_tag="VUZ44_002187"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VUZ44_002188"
     tRNA            complement(522..594)
                     /locus_tag="VUZ44_002188"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VUZ44_002189"
     tRNA            complement(619..691)
                     /locus_tag="VUZ44_002189"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVEHY010000094          616 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVEHY010000094 DAVEHY010000000
VERSION     DAVEHY010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.094"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..>616)
                     /locus_tag="VUZ44_002190"
     CDS             complement(<1..>616)
                     /locus_tag="VUZ44_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU0321003.1"
                     /translation="ISRLESGEFTPGADFLNALAKKLKVSMDYFFDEQVVEKVEELSE
                     FKKLAQTFITNRNYESLKYIYELENVKAHRLSLADKIYMEWIKSLIDFYFYGQKEDAI
                     VRLEGVLSQLSVSDLNYLQVSNTLFNFYYDIGDLGRFNKIREKLEYQVNHLNLSTIEE
                     LELSIKFNYNVCRYLWLQKNIEEAITKITATIKQCKAYRTNYLLA"
BASE COUNT          199 a          117 c           83 g          217 t
ORIGIN      
        1 cagccaaaag ataattcgtt ctgtaagcct tacattgttt tatagtagct gtaattttag
       61 taatagcttc ttcaatattt ttctgtaacc atagataacg acaaacgttg tagttaaact
      121 taatagatag ttctaactct tcgattgtac tcaaattgag gtgatttact tgatactcta
      181 gtttttcacg aattttattg aaacgaccta aatctccaat atcataataa aaattgaata
      241 gggtgtttga aacttggaga tagttcaaat cagatacact taactgtgat aataccccct
      301 ctaatcgtac aatcgcatct tctttctgtc cgtaaaaata aaaatctatc agagatttta
      361 tccattccat gtagatttta tctgctaaag ataggcggtg agcttttaca ttctccaatt
      421 catatatata tttcaaagac tcataattgc gatttgtaat aaatgtctgt gctaatttct
      481 taaattctga taactcctca actttctcta caacctgctc atcaaaaaaa taatccatac
      541 tgacttttaa cttcttagca agggcattca ggaaatccgc tccaggggta aactctccgc
      601 tctctaatcg actgat
//
LOCUS       DAVEHY010000095          591 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVEHY010000095 DAVEHY010000000
VERSION     DAVEHY010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.095"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..>591
                     /locus_tag="VUZ44_002191"
     CDS             <1..>591
                     /locus_tag="VUZ44_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0321004.1"
                     /translation="AKQVEALSRTKNELSGVKSAQATYEETTTRRLSELTNLANGKAS
                     KSELTQTAEELASRIASVQVGGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVS
                     DSPVTGFDKAIRLTSSNARDQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQA
                     NDNSGISPIFTLKDETWTKLSFTSARNRAGVASIGYV"
BASE COUNT          179 a          117 c          164 g          131 t
ORIGIN      
        1 gccaagcaag ttgaagcact tagccggact aaaaatgaac tgtctggcgt gaagtcagcg
       61 caagcgacgt atgaggagac gacgactcgt agactgtcag aactgaccaa cttggccaat
      121 ggtaaagcca gcaagtcaga actcacgcag acagctgagg agctggctag tcggatagcg
      181 agtgtgcagg tcgggggtag gaattatatc cggggtacaa agcgcatgat gctagccaga
      241 ggattgtggg catcaggtac ttttagaccg tcaggcgctg ggacggcaaa gacgattgat
      301 gtatcagaca gtccagtaac tggctttgat aaagcgatac gattgacctc aagcaatgct
      361 agagaccaaa taggtattgc tcaagatgga ttttatatct cgcaaggcac atacacgatg
      421 tcttgttggg tcaaaggcag aagaggtcaa aaggtcaagc tacaaactta ttggcaagcc
      481 aatgataatt cgggtatttc gcccatcttt acattaaagg atgaaacttg gacaaagcta
      541 tcgtttacta gcgctagaaa tagggctgga gtcgcatcaa ttggctatgt g
//
LOCUS       DAVEHY010000096          583 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVEHY010000096 DAVEHY010000000
VERSION     DAVEHY010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.096"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..>583
                     /locus_tag="VUZ44_002192"
     CDS             <1..>583
                     /locus_tag="VUZ44_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU0321005.1"
                     /translation="DDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDG
                     YIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQD
                     SGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWF
                     DEGLYEAPKGYTLEDLLATVKYYVEHPNERPHS"
BASE COUNT          185 a          124 c          128 g          146 t
ORIGIN      
        1 tggatgatat tcttgccttc ttagctccga ttcgtcatcc agaacgttta ggaaaaccaa
       61 atgcgcaaat tacctacact gatgatgaga ttcaagtagc caagttggca ggcaagtaca
      121 caacagaaga cggttatatc tttgatcctc gtgatataac cagtgatgag ggggatgcct
      181 atgtaactcc acatatgacc catagccact ggattaaaaa agatagtttg tctgaagctg
      241 agagagcggc agcccaggct tatgctaaag agaaaggttt gacccctcct tcgacagacc
      301 atcaggattc aggaaatact gaggcaaaag gagcagaagc tatctacaac cgcgtgaaag
      361 cagctaagaa ggtgccactt gatcgtatgc cttacaatct tcaatatact gtagaagtca
      421 aaaacggtag tttaatcata cctcattatg accattacca taacatcaaa tttgagtggt
      481 ttgacgaagg cctttatgag gcacctaagg ggtatactct tgaggatctt ttggcgactg
      541 tcaagtacta tgtcgaacat ccaaacgaac gtccgcattc aga
//
LOCUS       DAVEHY010000097          452 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVEHY010000097 DAVEHY010000000
VERSION     DAVEHY010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.097"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            22..>452
                     /locus_tag="VUZ44_002193"
     CDS             22..>452
                     /locus_tag="VUZ44_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0321006.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHF"
BASE COUNT          161 a          104 c           64 g          123 t
ORIGIN      
        1 caactcatta gaaagattca tatggaacaa ttacatttta tcacaaaact actcgatatc
       61 aaagacacaa atatccaaat tatagatgtc gtcaataggg attcacacaa agaaatcatc
      121 gccaaactgg actacgacgc accatcttgc cctgattgtg gaagtctaat gaagaaatat
      181 gactttcaaa aaccgtctaa gatcccttac ctcgaaacaa ctggtatgcc ttctagaatt
      241 ctccttagaa aacgccgttt caagtgctat cactgttcaa aaatgatggt tgctgagact
      301 cccctggtaa agaaaaatca ccaaatccct cgtatcatca accaaaaaat tgctcaaaag
      361 ttaattgaaa aaatttctat gactgatatt gcccatcagc tggccatttc aacttcaact
      421 gtcattcgca agctcaatga ctttcacttt ga
//
LOCUS       DAVEHY010000098          426 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVEHY010000098 DAVEHY010000000
VERSION     DAVEHY010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.098"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..237)
                     /locus_tag="VUZ44_002194"
     CDS             complement(<1..237)
                     /locus_tag="VUZ44_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU0321007.1"
                     /translation="MKILNIELANVEQTDLGFEHWVDVTYQVPILKNEYTVKLLLLME
                     CRIEDQEVIEYLVSTWKYRDLVLHSVRMYEIEKSE"
BASE COUNT          143 a           97 c           49 g          137 t
ORIGIN      
        1 ctcactcttt tctatctcat acatccttac cgaatgcaac acgagatcac gatacttcca
       61 agtgctgacc agatactcaa taacctcttg gtcctctatc ctgcattcca taagtaataa
      121 tagtttgacc gtgtattcat tcttcaaaat cggaacctga taagtcacat ctacccaatg
      181 ctcaaaacct aagtctgtct gctctacatt tgctagttca atatttaaaa tcttcatttt
      241 tattcctcct acttatctat tcgtaaaaga agataaaaag ttatgaaaaa atcattactt
      301 ttttaattca gacagtactt tcagagcaat tttgttaatg tcaacaaaat tggcaaccaa
      361 gcgatttaat actatttgtt gacgccaaca agtcaatttt cagacaaaca aaaaaaccgc
      421 aagcct
//
LOCUS       DAVEHY010000099          366 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVEHY010000099 DAVEHY010000000
VERSION     DAVEHY010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.099"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            complement(<1..>366)
                     /locus_tag="VUZ44_002195"
     CDS             complement(<1..>366)
                     /locus_tag="VUZ44_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU0321008.1"
                     /translation="QHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSD
                     KRFYRPTFRMHLTNKEILDKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNL
                     KQAHPIFQTVFKTFLKDKEK"
BASE COUNT          107 a           64 c           77 g          118 t
ORIGIN      
        1 cttttcttta tctttgagga aggttttaaa gacagtctga aaaataggat gagcctgctt
       61 aagattgtcc tcaataagtc cgaaaaattt ctctggttcc ttattctgga agtgaaacag
      121 caagagctga tagagctgat agtggtgttt caagtcttct gaatagctca aaagcttgtc
      181 taaaatctct ttattggtta aatgcatacg aaaagtagga cgataaaatc gcttatcact
      241 cagtttacgg ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
      301 ggattttcga tgaaactgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      361 atgttg
//
LOCUS       DAVEHY010000100          349 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVEHY010000100 DAVEHY010000000
VERSION     DAVEHY010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.100"
                     /strain="307"
                     /db_xref="taxon:1313"
BASE COUNT          149 a           39 c           63 g           98 t
ORIGIN      
        1 taaaagttcg gtgaaagaat attttgagac ggcatatttt ctatacaaac ttgaggagaa
       61 catgtcaatg actctgaaag ttgagcatta cattgcagat ataacagaat aatgaatacg
      121 gtgttcaagt gagcatcgtt tttcaaacct agttcagata caaaaaagta tcaaacaaaa
      181 aaaaataaaa aaacattata aaaaaattga caagctaatt ttgaagtgat aaaataaatg
      241 caagaaaaca aaaggagagg tatatgagaa gtttgtttaa gaaaatagtt gctgtattag
      301 ttattggctt aattctgtta ggaattgcga gaacacctca agttcataa
//
LOCUS       DAVEHY010000101          339 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVEHY010000101 DAVEHY010000000
VERSION     DAVEHY010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.101"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            231..>339
                     /locus_tag="VUZ44_002196"
     CDS             231..>339
                     /locus_tag="VUZ44_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU0321009.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGL"
BASE COUNT          115 a           53 c           76 g           95 t
ORIGIN      
        1 taccttagtc aagaattaga tgtttcacta tgtttgagta agttgatgat ttcatttgat
       61 aacaggtttg aaactgttag gctaggtggc caaggctaat catagccttg gtttagctga
      121 aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca
      181 cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag atgcaagaac
      241 attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt gagcggtgga
      301 agaatgaaaa taagtccaat cgtgaaattg caggcttgt
//
LOCUS       DAVEHY010000102          323 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVEHY010000102 DAVEHY010000000
VERSION     DAVEHY010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.102"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..>323
                     /locus_tag="VUZ44_002197"
     CDS             <1..>323
                     /locus_tag="VUZ44_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU0321010.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVI"
BASE COUNT          128 a           32 c           60 g          103 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tat
//
LOCUS       DAVEHY010000103          309 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVEHY010000103 DAVEHY010000000
VERSION     DAVEHY010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.103"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            <1..279
                     /locus_tag="VUZ44_002198"
     CDS             <1..279
                     /locus_tag="VUZ44_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU0321011.1"
                     /translation="LDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHE
                     TLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          123 a           44 c           68 g           74 t
ORIGIN      
        1 ttagactata tccgtaaaca ggaaagtcag aagcgtagat acgataaaga accctatgaa
       61 gaagtgggtg agatcagtca tcgtataagt gaggggggtc tctggctaga tgattattat
      121 ctctttcatg aaacactaag agattataga aacaaacaaa gtaaagagaa acaagaagaa
      181 ctagaacgcg tcttaagcaa tgaacgattt cgagggcgtc aaagagtatt aagagactta
      241 cgcattgtgt ttaaggagtt tactatccgt acccattagt aagtcatgca aaaaaaatga
      301 aaaaaatta
//
LOCUS       DAVEHY010000104          293 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 307
            SAMEA2446393-rid19717173.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVEHY010000104 DAVEHY010000000
VERSION     DAVEHY010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446393
            Sequence Read Archive: ERR540357
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929349.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929349.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:42:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,199
            CDSs (total)                      :: 2,155
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 39 of 135
            Pseudo Genes (multiple problems)  :: 26 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446393-rid19717173.denovo.104"
                     /strain="307"
                     /db_xref="taxon:1313"
     gene            62..>293
                     /locus_tag="VUZ44_002199"
     CDS             62..>293
                     /locus_tag="VUZ44_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU0321012.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPIL"
BASE COUNT           96 a           56 c           59 g           82 t
ORIGIN      
        1 tacattgctg aagcaaccgc ttaatcttgt ctattaaaaa ataaaatcgg aggaaatcca
       61 aatgattaaa attcttgctg cctgcggtgc aggtgttaac tcaagtcacc aaattaaaag
      121 tgctctagaa gaagaacttt caaaccgtgg ttatgatgtt cactgtgatg cagtcatggt
      181 gaaagatgta aacgaagacc ttatgaaagg ttacgatatc tttacaccaa tcgctgcaac
      241 agaccttggt tttgaaccag gtatcccagt tatcgaagct gggccaatct tat
//
